AR034712A1 - Forma de dosificacion de nucleo suave, de revestimiento fragil - Google Patents

Forma de dosificacion de nucleo suave, de revestimiento fragil

Info

Publication number
AR034712A1
AR034712A1 ARP020102441A ARP020102441A AR034712A1 AR 034712 A1 AR034712 A1 AR 034712A1 AR P020102441 A ARP020102441 A AR P020102441A AR P020102441 A ARP020102441 A AR P020102441A AR 034712 A1 AR034712 A1 AR 034712A1
Authority
AR
Argentina
Prior art keywords
dosage form
soft nucleus
fragile coating
particles
fragile
Prior art date
Application number
ARP020102441A
Other languages
English (en)
Original Assignee
Mcneil Ppc Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mcneil Ppc Inc filed Critical Mcneil Ppc Inc
Publication of AR034712A1 publication Critical patent/AR034712A1/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/485Morphinan derivatives, e.g. morphine, codeine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/192Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4402Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 2, e.g. pheniramine, bisacodyl
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806Coating materials
    • A61K9/282Organic compounds, e.g. fats
    • A61K9/2826Sugars or sugar alcohols, e.g. sucrose; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806Coating materials
    • A61K9/2833Organic macromolecular compounds
    • A61K9/286Polysaccharides, e.g. gums; Cyclodextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2072Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A61K9/2081Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50

Abstract

Una forma de dosificación oral para suministrar agentes activos que tiene un núcleo suave con partículas de un agente activo, los cuales tienen un tamano promedio mayor a aproximadamente 50 micrones, y una cubierta frágil que encierra el núcleo suave, en donde la relación en peso de partículas a cubierta es de aproximadamente 1.0:0.5 a aproximadamente 1.0:15
ARP020102441A 2001-06-29 2002-06-28 Forma de dosificacion de nucleo suave, de revestimiento fragil AR034712A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US09/896,052 US7914811B2 (en) 2001-06-29 2001-06-29 Brittle-coating, soft core dosage form

Publications (1)

Publication Number Publication Date
AR034712A1 true AR034712A1 (es) 2004-03-17

Family

ID=25405545

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP020102441A AR034712A1 (es) 2001-06-29 2002-06-28 Forma de dosificacion de nucleo suave, de revestimiento fragil

Country Status (9)

Country Link
US (1) US7914811B2 (es)
EP (1) EP1273291A1 (es)
JP (1) JP2003095927A (es)
KR (1) KR20030009137A (es)
CN (1) CN1394598A (es)
AR (1) AR034712A1 (es)
BR (1) BR0202491A (es)
CA (1) CA2391439C (es)
MX (1) MXPA02006603A (es)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6773744B1 (en) * 2000-11-06 2004-08-10 Hershey Foods Corporation Confectionary products, low fat chocolate and chocolate-like products and methods for making them
US20030203019A1 (en) * 2002-04-30 2003-10-30 Cornelius John Mark Coated conditioners for use in foods and pharmaceuticals
US20040052851A1 (en) * 2002-09-16 2004-03-18 Graff Allan H. Modified release oral dosage form
US20080213363A1 (en) * 2003-01-23 2008-09-04 Singh Nikhilesh N Methods and compositions for delivering 5-HT3 antagonists across the oral mucosa
US7838029B1 (en) * 2003-07-31 2010-11-23 Watson Laboratories, Inc. Mirtazapine solid dosage forms
EP1582221A1 (en) * 2004-03-31 2005-10-05 Chiesi S.A. Pharmaceutical oral compositions with a taste masking effect
US7811604B1 (en) 2005-11-14 2010-10-12 Barr Laboratories, Inc. Non-effervescent, orally disintegrating solid pharmaceutical dosage forms comprising clozapine and methods of making and using the same
WO2007058644A1 (en) * 2005-11-15 2007-05-24 Wm. Wrigley Jr. Company Methods of producing coated products including active agent and products regarding same
US7767248B2 (en) * 2007-02-02 2010-08-03 Overly Iii Harry J Soft chew confectionary with high fiber and sugar content and method for making same
EP2124907B1 (en) 2007-03-19 2018-05-30 Vita Sciences, Llc Transdermal patch and method for delivery of vitamin b12
US20090011079A1 (en) * 2007-07-02 2009-01-08 Bestsweet, Inc. Hard Coated Confectionary Having A Consumable Soft Chewing Core With An Active And Method For Making Same
JP2011505142A (ja) * 2007-11-29 2011-02-24 キャドバリー アダムス ユーエスエー エルエルシー 微粒子コーティング加工
CN102439587A (zh) * 2009-04-23 2012-05-02 托马斯·F.·小奎恩 用于提交法律文件的系统和方法
US9375033B2 (en) 2014-02-14 2016-06-28 R.J. Reynolds Tobacco Company Tobacco-containing gel composition
US9474699B2 (en) * 2014-03-31 2016-10-25 Johnson & Johnson Consumer Inc. Compostions and methods for enhancing the topical application of a basic benefit agent
US9468606B2 (en) * 2014-03-31 2016-10-18 Johnson & Johnson Consumer Inc. Compostions and methods for enhancing the topical application of an acidic benefit agent
RU2017101050A (ru) 2014-06-16 2018-07-16 Джонсон энд Джонсон Консьюмер Инк. Композиции и способы повышения эффективности местного нанесения окрашенного косметического средства
US20190022013A1 (en) 2015-12-19 2019-01-24 First Time Us Generics Llc Soft-chew tablet pharmaceutical formulations
EP3389628A4 (en) 2015-12-19 2019-08-07 Dixit, Manesh A. PHARMACEUTICAL FORMULATIONS OF MOUSE CHEESE TABLETS
EP3612570A4 (en) 2017-04-17 2021-01-13 The University of Chicago POLYMER MATERIALS FOR DELIVERING SHORT CHAIN FATTY ACIDS TO THE INTESTINAL FOR HUMAN HEALTH APPLICATIONS AND DISEASE TREATMENT

Family Cites Families (24)

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Publication number Priority date Publication date Assignee Title
US4271142A (en) * 1979-06-18 1981-06-02 Life Savers, Inc. Portable liquid antacids
US4260596A (en) * 1979-08-13 1981-04-07 Bristol-Myers Company Edible unit dosage form consisting of outer mannitol shell and inner liquid or gel center and method for manufacturing the same
US4327076A (en) 1980-11-17 1982-04-27 Life Savers, Inc. Compressed chewable antacid tablet and method for forming same
US4643894A (en) 1984-07-24 1987-02-17 Colorcon, Inc. Maltodextrin coating
US4684534A (en) 1985-02-19 1987-08-04 Dynagram Corporation Of America Quick-liquifying, chewable tablet
US4800087A (en) * 1986-11-24 1989-01-24 Mehta Atul M Taste-masked pharmaceutical compositions
US4828845A (en) 1986-12-16 1989-05-09 Warner-Lambert Company Xylitol coated comestible and method of preparation
US4753790A (en) * 1986-12-16 1988-06-28 Warner-Lambert Company Sorbitol coated comestible and method of preparation
US4851226A (en) 1987-11-16 1989-07-25 Mcneil Consumer Products Company Chewable medicament tablet containing means for taste masking
US5102664A (en) 1989-07-19 1992-04-07 Day Charles E Good-tasting gritty drug formulations
US5362508A (en) 1989-09-20 1994-11-08 Nabisco, Inc. Process for preparing soft centers in food products
US5075114A (en) 1990-05-23 1991-12-24 Mcneil-Ppc, Inc. Taste masking and sustained release coatings for pharmaceuticals
CA2068402C (en) 1991-06-14 1998-09-22 Michael R. Hoy Taste mask coatings for preparation of chewable pharmaceutical tablets
ATE147261T1 (de) 1992-01-13 1997-01-15 Pfizer Verfahren zur herstellung von tabletten mit hoher festigkeit
WO1993024109A1 (en) * 1992-06-04 1993-12-09 Smithkline Beecham Corporation Palatable pharmaceutical compositions
EP0662821A4 (en) 1992-09-30 1996-02-28 Ascent Pharma Inc CALCIUM POLYCARBOPHIL SPREADING POWDER.
AU1655595A (en) * 1994-04-29 1995-11-09 Mcneil-Ppc, Inc. Solid pharmaceutical dosage form containing flavored film coating
JP3482242B2 (ja) * 1994-06-10 2003-12-22 株式会社キティー 生理活性物質の封入されている微粒子及びその製法
GB9612821D0 (en) 1996-06-19 1996-08-21 Cerestar Holding Bv Sugarfree hard coatings and a method for obtaining them
AU722289B2 (en) * 1996-10-01 2000-07-27 Aptalis Pharmatech, Inc. Taste-masked microcapsule compositions and methods of manufacture
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US6060078A (en) * 1998-09-28 2000-05-09 Sae Han Pharm Co., Ltd. Chewable tablet and process for preparation thereof
US6077557A (en) 1998-11-20 2000-06-20 General Mills, Inc. Gel products fortified with calcium and method of preparation

Also Published As

Publication number Publication date
CA2391439A1 (en) 2002-12-29
BR0202491A (pt) 2003-04-29
JP2003095927A (ja) 2003-04-03
US20030017202A1 (en) 2003-01-23
US7914811B2 (en) 2011-03-29
CN1394598A (zh) 2003-02-05
CA2391439C (en) 2011-07-19
EP1273291A1 (en) 2003-01-08
MXPA02006603A (es) 2004-08-19
KR20030009137A (ko) 2003-01-29

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