AR029493A1 - A SILICONE HYDROGEL MONOMERO FORMULATION AND METHODS TO STABILIZE AN INITIATING SYSTEM AND A SILICONE HYDROGEL MONOMERO FORMULATION - Google Patents

A SILICONE HYDROGEL MONOMERO FORMULATION AND METHODS TO STABILIZE AN INITIATING SYSTEM AND A SILICONE HYDROGEL MONOMERO FORMULATION

Info

Publication number
AR029493A1
AR029493A1 ARP010101318A ARP010101318A AR029493A1 AR 029493 A1 AR029493 A1 AR 029493A1 AR P010101318 A ARP010101318 A AR P010101318A AR P010101318 A ARP010101318 A AR P010101318A AR 029493 A1 AR029493 A1 AR 029493A1
Authority
AR
Argentina
Prior art keywords
formulation
silicone hydrogel
monomero
stabilize
methods
Prior art date
Application number
ARP010101318A
Other languages
Spanish (es)
Original Assignee
Johnson & Johnson Vision Care
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Johnson & Johnson Vision Care filed Critical Johnson & Johnson Vision Care
Publication of AR029493A1 publication Critical patent/AR029493A1/en

Links

Classifications

    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B1/00—Optical elements characterised by the material of which they are made; Optical coatings for optical elements
    • G02B1/04—Optical elements characterised by the material of which they are made; Optical coatings for optical elements made of organic materials, e.g. plastics
    • G02B1/041—Lenses
    • G02B1/043—Contact lenses
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F2/00—Processes of polymerisation
    • C08F2/46—Polymerisation initiated by wave energy or particle radiation
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F230/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and containing phosphorus, selenium, tellurium or a metal
    • C08F230/04—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and containing phosphorus, selenium, tellurium or a metal containing a metal
    • C08F230/08—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and containing phosphorus, selenium, tellurium or a metal containing a metal containing silicon
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F290/00—Macromolecular compounds obtained by polymerising monomers on to polymers modified by introduction of aliphatic unsaturated end or side groups
    • C08F290/08—Macromolecular compounds obtained by polymerising monomers on to polymers modified by introduction of aliphatic unsaturated end or side groups on to polymers modified by introduction of unsaturated side groups
    • C08F290/14—Polymers provided for in subclass C08G
    • C08F290/148—Polysiloxanes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S524/00—Synthetic resins or natural rubbers -- part of the class 520 series
    • Y10S524/916—Hydrogel compositions

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Polymerisation Methods In General (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Dental Preparations (AREA)
  • Eyeglasses (AREA)
  • Materials For Medical Uses (AREA)

Abstract

La formulacion monomérica de hidrogel de silicona se prepara mezclando una mezcla formadora de hidrogel de silicona, un iniciador de acilfosfina, y un ácido. Los sistemas iniciadores de acilfosfinas y las formulaciones usados en la fabricacion de lentes oftálmicos son estabilizados por la disminucion del pH del sistema o por el agregado de un ácido a la mezcla de monomero para fabricar lentes oftálmicas. La estabilidad del sistema iniciador incrementa el tiempo de trabajo de la formulacion ya que reduce la necesidad de preparar los materiales de partida y la posibilidad de introducir variaciones lote a lote y variaciones intra-lote en la produccion de lentes.The monomeric silicone hydrogel formulation is prepared by mixing a silicone hydrogel-forming mixture, an acylphosphine initiator, and an acid. The acylphosphine initiator systems and the formulations used in the manufacture of ophthalmic lenses are stabilized by the decrease in the pH of the system or by the addition of an acid to the monomer mixture to manufacture ophthalmic lenses. The stability of the initiator system increases the working time of the formulation as it reduces the need to prepare the starting materials and the possibility of introducing batch-to-batch variations and intra-batch variations in the production of lenses.

ARP010101318A 2000-03-22 2001-03-21 A SILICONE HYDROGEL MONOMERO FORMULATION AND METHODS TO STABILIZE AN INITIATING SYSTEM AND A SILICONE HYDROGEL MONOMERO FORMULATION AR029493A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US09/532,234 US6414049B1 (en) 2000-03-22 2000-03-22 Stable initiator system

Publications (1)

Publication Number Publication Date
AR029493A1 true AR029493A1 (en) 2003-07-02

Family

ID=24120922

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP010101318A AR029493A1 (en) 2000-03-22 2001-03-21 A SILICONE HYDROGEL MONOMERO FORMULATION AND METHODS TO STABILIZE AN INITIATING SYSTEM AND A SILICONE HYDROGEL MONOMERO FORMULATION

Country Status (13)

Country Link
US (1) US6414049B1 (en)
EP (1) EP1268581B1 (en)
JP (1) JP2003528178A (en)
KR (1) KR100746500B1 (en)
CN (1) CN1222551C (en)
AR (1) AR029493A1 (en)
AU (2) AU2001249321B2 (en)
BR (1) BR0109481A (en)
CA (1) CA2404118A1 (en)
DE (1) DE60107402T2 (en)
HK (1) HK1050018B (en)
TW (1) TWI257396B (en)
WO (1) WO2001070824A2 (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7052131B2 (en) * 2001-09-10 2006-05-30 J&J Vision Care, Inc. Biomedical devices containing internal wetting agents
US6822016B2 (en) 2001-09-10 2004-11-23 Johnson & Johnson Vision Care, Inc. Biomedical devices containing internal wetting agents
US6414049B1 (en) 2000-03-22 2002-07-02 Johnson & Johnson Vision Care, Inc. Stable initiator system
US6908978B2 (en) 2001-11-02 2005-06-21 Bausch & Lomb Incorporated High refractive index polymeric siloxysilane compositions
US6776934B2 (en) * 2001-11-02 2004-08-17 Bausch & Lomb Incorporated Method for polymerizing lenses
US6936641B2 (en) * 2002-06-25 2005-08-30 Johnson & Johnson Vision Care, Inc. Macromer forming catalysts
ATE526597T1 (en) * 2005-08-09 2011-10-15 Coopervision Int Holding Co Lp MANUFACTURING PROCESS AND CONDITIONS FOR SILICONE HYDROGEL POLYMER CONTACT LENSES
CN101595139B (en) * 2007-01-17 2012-08-22 可乐丽则武齿科株式会社 Polymerizable monomer-containing composition
CN102666731B (en) * 2009-12-04 2014-12-31 道康宁公司 Stabilization of silsesquioxane resins
WO2016143565A1 (en) * 2015-03-12 2016-09-15 旭硝子株式会社 Method for producing laminate, laminate and photocurable composition
US10676575B2 (en) * 2016-10-06 2020-06-09 Johnson & Johnson Vision Care, Inc. Tri-block prepolymers and their use in silicone hydrogels
US10996491B2 (en) 2018-03-23 2021-05-04 Johnson & Johnson Vision Care, Inc. Ink composition for cosmetic contact lenses
US11891526B2 (en) 2019-09-12 2024-02-06 Johnson & Johnson Vision Care, Inc. Ink composition for cosmetic contact lenses
CN112708056B (en) * 2020-10-30 2022-10-18 科之杰新材料集团河南有限公司 Viscosity-reducing polycarboxylate superplasticizer for concrete member and preparation method thereof

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4136250A (en) * 1977-07-20 1979-01-23 Ciba-Geigy Corporation Polysiloxane hydrogels
US4153641A (en) * 1977-07-25 1979-05-08 Bausch & Lomb Incorporated Polysiloxane composition and contact lens
US4414372A (en) 1982-06-17 1983-11-08 E. I. Du Pont De Nemours & Co. Process for preparing living polymers
US4711942A (en) 1983-11-07 1987-12-08 E. I. Du Pont De Nemours And Company "Living" polymers and process for their preparation
DE3633436A1 (en) 1986-10-01 1988-04-14 Basf Ag PHOTOPOLYMERIZABLE RECORDING MEASURES, IN PARTICULAR FOR THE PRODUCTION OF PRINTING PLATES AND RELIEF FORMS
US4740533A (en) * 1987-07-28 1988-04-26 Ciba-Geigy Corporation Wettable, flexible, oxygen permeable, substantially non-swellable contact lens containing block copolymer polysiloxane-polyoxyalkylene backbone units, and use thereof
US4771116A (en) 1987-04-30 1988-09-13 E. I. Du Pont De Nemours And Company Silylamines as additives in group transfer polymerization
US5019634A (en) 1988-02-16 1991-05-28 E. I. Du Pont De Nemours And Company Group transfer living polymer grafted to an initiator support
US5021524A (en) 1988-04-14 1991-06-04 E. I. Du Pont De Nemours And Company Initiator for group transfer polymerization
US5070215A (en) * 1989-05-02 1991-12-03 Bausch & Lomb Incorporated Novel vinyl carbonate and vinyl carbamate contact lens material monomers
US5034461A (en) * 1989-06-07 1991-07-23 Bausch & Lomb Incorporated Novel prepolymers useful in biomedical devices
US5310779A (en) * 1991-11-05 1994-05-10 Bausch & Lomb Incorporated UV curable crosslinking agents useful in copolymerization
US5358995A (en) * 1992-05-15 1994-10-25 Bausch & Lomb Incorporated Surface wettable silicone hydrogels
US5260000A (en) * 1992-08-03 1993-11-09 Bausch & Lomb Incorporated Process for making silicone containing hydrogel lenses
ZA941879B (en) * 1993-03-18 1994-09-19 Ciba Geigy Curing compositions containing bisacylphosphine oxide photoinitiators
US5760100B1 (en) 1994-09-06 2000-11-14 Ciba Vision Corp Extended wear ophthalmic lens
US5658995A (en) * 1995-11-27 1997-08-19 Rutgers, The State University Copolymers of tyrosine-based polycarbonate and poly(alkylene oxide)
SG54538A1 (en) 1996-08-05 1998-11-16 Hoya Corp Soft contact lens with high moisture content and method for producing the same
US6075065A (en) 1996-12-20 2000-06-13 Takeda Chemical Industries, Ltd. Photocurable resin composition and a method for producing the same
JPH10231340A (en) * 1996-12-20 1998-09-02 Takeda Chem Ind Ltd Photocurable composition resin composition and its production
US6367929B1 (en) * 1998-03-02 2002-04-09 Johnson & Johnson Vision Care, Inc. Hydrogel with internal wetting agent
US6031059A (en) 1998-09-30 2000-02-29 Johnson & Johnson Vision Products, Inc. Optically transparent hydrogels and processes for their production
SE9803481D0 (en) * 1998-10-13 1998-10-13 Pharmacia & Upjohn Ab Photocurable siloxane polymers
US6414049B1 (en) 2000-03-22 2002-07-02 Johnson & Johnson Vision Care, Inc. Stable initiator system

Also Published As

Publication number Publication date
WO2001070824A2 (en) 2001-09-27
HK1050018B (en) 2005-05-27
TWI257396B (en) 2006-07-01
AU4932101A (en) 2001-10-03
AU2001249321B2 (en) 2006-02-02
BR0109481A (en) 2004-01-13
EP1268581A2 (en) 2003-01-02
JP2003528178A (en) 2003-09-24
EP1268581B1 (en) 2004-11-24
CN1222551C (en) 2005-10-12
DE60107402D1 (en) 2004-12-30
DE60107402T2 (en) 2005-12-22
CA2404118A1 (en) 2001-09-27
KR100746500B1 (en) 2007-08-07
WO2001070824A3 (en) 2002-06-27
CN1430629A (en) 2003-07-16
HK1050018A1 (en) 2003-06-06
US6414049B1 (en) 2002-07-02
KR20020091146A (en) 2002-12-05

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