AR004223A1 - COMPOSITIONS TO INHIBIT THE ADDING OF PLATELETS AND THE USE OF THE SAME IN THE MANUFACTURE OF A MEDICINAL PRODUCT. - Google Patents
COMPOSITIONS TO INHIBIT THE ADDING OF PLATELETS AND THE USE OF THE SAME IN THE MANUFACTURE OF A MEDICINAL PRODUCT.Info
- Publication number
- AR004223A1 AR004223A1 ARP960104786A ARP960104786A AR004223A1 AR 004223 A1 AR004223 A1 AR 004223A1 AR P960104786 A ARP960104786 A AR P960104786A AR P960104786 A ARP960104786 A AR P960104786A AR 004223 A1 AR004223 A1 AR 004223A1
- Authority
- AR
- Argentina
- Prior art keywords
- manufacture
- effective
- platelets
- inhibit
- compositions
- Prior art date
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
La invención es una composición farmacéutica para inhibir la agregación de plaquetas, para administrarla intra-venosamente a un paciente, que comprende:a) una cantidad farmacéuticamente efectiva de una compuesto que tiene la fórmula (I), donde: R4 es arilo, alquilo C1-10 ó arilalquilo C1-10; R5 es (II),donde R8 es hidroxi o alquiloxi C1-10; p es cero ó uno; y m es un número entero desde dos hasta seis; por ej. ácido 2-S-(n-butilsulfonilamino)-3-[4-(4-(piperidin-4-il)butiloxi)fenil]propiónico: b) una cantidad farmacéuticamente aceptable de un tampón citrato, efectivo para proveer un pH desde alrededor de5 hasta alrededor de 7; y c) una cantidad farmacéuticamente aceptable de un agente ajustador de tonicidad, efectivo para hacer a la formulaciónsustancialmente isotónica con la presión osmótica del sistema biológico del paciente. Se describe además el uso de la misma en la manufactura de unmedicamento.The invention is a pharmaceutical composition for inhibiting platelet aggregation, for intravenous administration to a patient, comprising: a) a pharmaceutically effective amount of a compound having formula (I), where: R4 is aryl, C1-alkyl -10 or C1-10 arylalkyl; R5 is (II), where R8 is hydroxy or C1-10 alkyloxy; p is zero or one; and m is an integer from two to six; for example 2-S- (n-Butylsulfonylamino) -3- [4- (4- (piperidin-4-yl) butyloxy) phenyl] propionic acid: b) a pharmaceutically acceptable amount of a citrate buffer, effective in providing a pH from about from 5 to around 7; and c) a pharmaceutically acceptable amount of a tonicity adjusting agent, effective to render the formulation substantially isotonic with the osmotic pressure of the patient's biological system. The use of it in the manufacture of a drug is also described.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US590795P | 1995-10-27 | 1995-10-27 | |
GBGB9603721.3A GB9603721D0 (en) | 1996-02-22 | 1996-02-22 | Composition for inhibiting platelet aggregation |
Publications (1)
Publication Number | Publication Date |
---|---|
AR004223A1 true AR004223A1 (en) | 1998-11-04 |
Family
ID=10789191
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP960104786A AR004223A1 (en) | 1995-10-27 | 1996-10-17 | COMPOSITIONS TO INHIBIT THE ADDING OF PLATELETS AND THE USE OF THE SAME IN THE MANUFACTURE OF A MEDICINAL PRODUCT. |
Country Status (2)
Country | Link |
---|---|
AR (1) | AR004223A1 (en) |
GB (1) | GB9603721D0 (en) |
-
1996
- 1996-02-22 GB GBGB9603721.3A patent/GB9603721D0/en active Pending
- 1996-10-17 AR ARP960104786A patent/AR004223A1/en unknown
Also Published As
Publication number | Publication date |
---|---|
GB9603721D0 (en) | 1996-04-24 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN1561209A (en) | Pharmaceutical compositions containing beta-lapachone, or derivatives or analogs thereof, and methods of using same | |
AU5262300A (en) | New use of compounds as antibacterial agents | |
NO2000010I1 (en) | Pharmaceutically acceptable salts of esomeprazole | |
GEP20053595B (en) | Cyclopentanoindoles, Compositions Containing Such Compounds and Methods of Treatment | |
EP0693924A4 (en) | METHODS FOR -i(IN VIVO) DELIVERY OF BIOLOGICS AND COMPOSITIONS USEFUL THEREFOR | |
FI872864A (en) | Process for the preparation of pharmaceutically active benzimidazole compounds | |
JPS6191131A (en) | Method and composition for preventing adsorption of pharmaceutical | |
AR006598A1 (en) | "ANTI-FUNGOUS COMPOSITIONS, ITS USE IN THE MANUFACTURE OF MEDICINES AND A PROCEDURE FOR THE PREPARATION" | |
ATE202931T1 (en) | MEDICINAL PREPARATIONS CONTAINING TAXAN DERIVATIVES | |
AR033688A1 (en) | RECONSTITUABLE PARENTERAL COMPOSITION | |
ES2104845T3 (en) | LIPOPHYL COMPOSITIONS OF SALTS OF OLIGOSACCHARID ANTIBIOTICS. | |
AR030039A1 (en) | PHARMACEUTICAL COMPOSITION THAT INCLUDES A SELECTIVE INHIBITOR DRUG OF CYCLOOXYGENASA-2, ITS USE IN THE MANUFACTURE OF A MEDICINAL PRODUCT TO TREAT OR PREVENT AFFECTIONS THROUGH CYCLOOXYGENASE-2 AND METHOD TO MAKE SUCH MEDICINAL PRODUCT | |
KR910014124A (en) | Swallowable Dosage Units Containing Colloidal Bismuth Subcitrate (CBS) | |
ATE110723T1 (en) | GASGASIC ACID INHIBITOR COMPOUNDS AND METHOD OF PREPARATION. | |
GEP20032970B (en) | Pharmaceutical Compositions of Tizoxanide and Nitazoxanide | |
ATE13488T1 (en) | GALLIUM CHLORIDE, A NEW ANTI-CANCER AGENT. | |
AR004223A1 (en) | COMPOSITIONS TO INHIBIT THE ADDING OF PLATELETS AND THE USE OF THE SAME IN THE MANUFACTURE OF A MEDICINAL PRODUCT. | |
ATE352287T1 (en) | WATER-BASED LIQUID PHARMACEUTICAL COMPOSITIONS IN SUSPENSION FORM FOR ORAL ADMINISTRATION OF IBUPROFEN | |
MX9803275A (en) | Pharmaceutical compositions containing platelet aggregation inhibitors. | |
ATE24398T1 (en) | MEDICINAL FORMULATION FOR ORAL USE CONTAINING AN ANTIBIOTIC GLYCOSIDE AND AN EXCIPIENTS. | |
ATE256134T1 (en) | SULFATED PHOSPHATIDYLINOSITOLS, THEIR PRODUCTION AND USE | |
YU81101A (en) | Polymorphs of a crystalline azabicyclo (2,2,2) octan-3-amine citrate and their pharmaceutical compositions | |
ATE223700T1 (en) | NEW INJECTABLE MEDICINAL PREPARATIONS CONTAINING RAMOPLAN | |
DE69211743D1 (en) | Medicinal product containing aureobasidine | |
AR011137A1 (en) | DERIVATIVES OF 4-AMINOETOXIINDAZOL, ITS USE FOR THE PREPARATION OF A MEDICINAL PRODUCT AND PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM |