AR003417A1 - Derivados de acido arilsulfonil hidroxamico y composicion que contiene los mismos. - Google Patents

Derivados de acido arilsulfonil hidroxamico y composicion que contiene los mismos.

Info

Publication number
AR003417A1
AR003417A1 ARP960102226A AR10222696A AR003417A1 AR 003417 A1 AR003417 A1 AR 003417A1 AR P960102226 A ARP960102226 A AR P960102226A AR 10222696 A AR10222696 A AR 10222696A AR 003417 A1 AR003417 A1 AR 003417A1
Authority
AR
Argentina
Prior art keywords
composition containing
hydroxamic acid
arilsulfonil
acid derivatives
peirodontal
Prior art date
Application number
ARP960102226A
Other languages
English (en)
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/IB1995/000279 external-priority patent/WO1996033172A1/en
Application filed by Pfizer filed Critical Pfizer
Publication of AR003417A1 publication Critical patent/AR003417A1/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/92Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with a hetero atom directly attached to the ring nitrogen atom
    • C07D211/96Sulfur atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Un compuesto derivado de ácido arilsulfonil hidroxámico de la fórmula (I) en la que R1, R2, R3, R4, R5, R6, R7, R8, R9 y Ar son como se han definido enla memoria descriptiva, útil para el tratamiento de un trastorno seleccionado entre el grupo formado por artritis, cáncer,ulceración del tejido, reestenosis,enfermedad peirodontal,epidermólisis vesicular, escleritis y otras enfermedades caracterizadas por la actividad de metaloproteinasa de la matriz, así comoSIDA, septicemia, choque séptico yotras enfermedades que implican la producción del factor de necrosis de tumor (TNF). Se provee también unacomposición que contienen dichos compuestos.
ARP960102226A 1995-04-20 1996-04-17 Derivados de acido arilsulfonil hidroxamico y composicion que contiene los mismos. AR003417A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/IB1995/000279 WO1996033172A1 (en) 1995-04-20 1995-04-20 Arylsulfonyl hydroxamic acid derivatives as mmp and tnf inhibitors

Publications (1)

Publication Number Publication Date
AR003417A1 true AR003417A1 (es) 1998-08-05

Family

ID=51982970

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP960102226A AR003417A1 (es) 1995-04-20 1996-04-17 Derivados de acido arilsulfonil hidroxamico y composicion que contiene los mismos.

Country Status (2)

Country Link
KR (1) KR100194258B1 (es)
AR (1) AR003417A1 (es)

Also Published As

Publication number Publication date
KR960037658A (ko) 1996-11-19
KR100194258B1 (ko) 1999-06-15

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