AP2613A - Combination of a bis-thiazolium salt or a precursor thereof and atremisinin or a derivative thereof for treating acute malaria - Google Patents

Combination of a bis-thiazolium salt or a precursor thereof and atremisinin or a derivative thereof for treating acute malaria

Info

Publication number
AP2613A
AP2613A AP2010005353A AP2010005353A AP2613A AP 2613 A AP2613 A AP 2613A AP 2010005353 A AP2010005353 A AP 2010005353A AP 2010005353 A AP2010005353 A AP 2010005353A AP 2613 A AP2613 A AP 2613A
Authority
AP
ARIPO
Prior art keywords
atremisinin
precursor
bis
derivative
combination
Prior art date
Application number
AP2010005353A
Other languages
English (en)
Other versions
AP2010005353A0 (en
Inventor
Laurent Fraisse
Henri Vial
Sharon Aurore Wein
Original Assignee
Sanofi Aventis
Centre Nat Rech Scient
Univ Montpellier Ii
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39705083&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AP2613(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sanofi Aventis, Centre Nat Rech Scient, Univ Montpellier Ii filed Critical Sanofi Aventis
Publication of AP2010005353A0 publication Critical patent/AP2010005353A0/en
Application granted granted Critical
Publication of AP2613A publication Critical patent/AP2613A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/426—1,3-Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/357—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
    • A61K31/37—Coumarins, e.g. psoralen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/06—Antimalarials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AP2010005353A 2008-02-06 2009-02-05 Combination of a bis-thiazolium salt or a precursor thereof and atremisinin or a derivative thereof for treating acute malaria AP2613A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0800618A FR2926993B1 (fr) 2008-02-06 2008-02-06 Association entre un sel de bis-thiazolium ou l'un de ses precurseurs et l'artemisinine ou l'un de ses derives pour le traitement du paludisme
PCT/FR2009/000129 WO2009115666A2 (fr) 2008-02-06 2009-02-05 Association entre un sel de bis-thiazolium ou l'un de ses precurseurs et l'artémisinine ou l'un de ses derives pour le traitement du paludisme severe

Publications (2)

Publication Number Publication Date
AP2010005353A0 AP2010005353A0 (en) 2010-08-31
AP2613A true AP2613A (en) 2013-03-13

Family

ID=39705083

Family Applications (1)

Application Number Title Priority Date Filing Date
AP2010005353A AP2613A (en) 2008-02-06 2009-02-05 Combination of a bis-thiazolium salt or a precursor thereof and atremisinin or a derivative thereof for treating acute malaria

Country Status (40)

Country Link
US (1) US8304440B2 (de)
EP (1) EP2252286B1 (de)
JP (1) JP5469095B2 (de)
KR (1) KR20100137442A (de)
CN (1) CN101980706B (de)
AP (1) AP2613A (de)
AR (1) AR070581A1 (de)
AT (1) ATE521347T1 (de)
AU (1) AU2009227092B2 (de)
BR (1) BRPI0907484A2 (de)
CA (1) CA2714184A1 (de)
CL (1) CL2009000264A1 (de)
CO (1) CO6300843A2 (de)
CR (1) CR11613A (de)
CY (1) CY1112113T1 (de)
DK (1) DK2252286T3 (de)
EA (1) EA022711B1 (de)
EC (1) ECSP10010381A (de)
ES (1) ES2372148T3 (de)
FR (1) FR2926993B1 (de)
HK (1) HK1152892A1 (de)
HR (1) HRP20110858T8 (de)
IL (1) IL207442A0 (de)
JO (1) JO2820B1 (de)
MA (1) MA32128B1 (de)
MX (1) MX2010008653A (de)
MY (1) MY150776A (de)
NI (1) NI201000135A (de)
NZ (1) NZ587232A (de)
PA (1) PA8815101A1 (de)
PE (1) PE20091410A1 (de)
PL (1) PL2252286T3 (de)
PT (1) PT2252286E (de)
RS (1) RS52046B (de)
SI (1) SI2252286T1 (de)
TW (1) TWI402071B (de)
UA (1) UA99510C2 (de)
UY (1) UY31640A1 (de)
WO (1) WO2009115666A2 (de)
ZA (1) ZA201005611B (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2951945B1 (fr) * 2009-11-05 2013-08-09 Sanofi Aventis Composition pharmaceutique
CN105705177B (zh) 2013-11-08 2019-10-22 艾克塞拉医疗公司 使用吸附介质诊断感染性疾病的方法
US10714230B2 (en) * 2017-12-06 2020-07-14 C3Nano Inc. Thin and uniform silver nanowires, method of synthesis and transparent conductive films formed from the nanowires
CN110604733A (zh) * 2019-09-19 2019-12-24 同济大学 青蒿素类药物与其它药物联用在制备抗疟疾药物中的应用

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2796642A1 (fr) * 1999-07-21 2001-01-26 Centre Nat Rech Scient Precurseurs de sels de bis-ammonium quaternaire et leurs applications comme prodrogues ayant une activite anti-parasitaire
FR2884715A1 (fr) * 2005-04-20 2006-10-27 Sanofi Aventis Sa Association entre la ferroquine et un derive d'artemisinine pour le traitement du paludisme

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1058717A (zh) * 1990-08-08 1992-02-19 中国人民解放军军事医学科学院微生物流行病研究所 抗疟新药—复方蒿甲醚及其制备方法
JP2003050535A (ja) * 2001-08-07 2003-02-21 T-Zone Corp ネットワーク教育システム、ネットワーク教育方法、および、プログラム

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2796642A1 (fr) * 1999-07-21 2001-01-26 Centre Nat Rech Scient Precurseurs de sels de bis-ammonium quaternaire et leurs applications comme prodrogues ayant une activite anti-parasitaire
FR2884715A1 (fr) * 2005-04-20 2006-10-27 Sanofi Aventis Sa Association entre la ferroquine et un derive d'artemisinine pour le traitement du paludisme

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
GELB ET AL: "Drug discovery for malaria: a very challenging and timely endeavor" CURRENT OPINION IN CHEMICAL BIOLOGY, CURRENT BIOLOGY LTD, LONDON, GB, vol. 11, no. 4, 27 ao�t 2007 (2007-08-27), pages 440-445, XP022216091 ISSN: 1367-5931 *

Also Published As

Publication number Publication date
FR2926993B1 (fr) 2011-03-11
NZ587232A (en) 2012-06-29
MA32128B1 (fr) 2011-03-01
ES2372148T3 (es) 2012-01-16
RS52046B (en) 2012-04-30
AP2010005353A0 (en) 2010-08-31
AR070581A1 (es) 2010-04-21
AU2009227092A1 (en) 2009-09-24
JO2820B1 (en) 2014-09-15
NI201000135A (es) 2011-04-27
HRP20110858T1 (hr) 2012-01-31
EA022711B1 (ru) 2016-02-29
CN101980706B (zh) 2013-11-27
HRP20110858T8 (en) 2012-02-29
TWI402071B (zh) 2013-07-21
WO2009115666A3 (fr) 2009-12-23
ECSP10010381A (es) 2010-11-30
BRPI0907484A2 (pt) 2019-09-24
CY1112113T1 (el) 2015-11-04
PL2252286T3 (pl) 2012-02-29
ZA201005611B (en) 2012-06-27
CN101980706A (zh) 2011-02-23
CR11613A (es) 2010-11-22
ATE521347T1 (de) 2011-09-15
PA8815101A1 (es) 2009-09-17
JP2011514319A (ja) 2011-05-06
PE20091410A1 (es) 2009-10-14
JP5469095B2 (ja) 2014-04-09
DK2252286T3 (da) 2011-12-19
WO2009115666A2 (fr) 2009-09-24
SI2252286T1 (sl) 2012-01-31
CA2714184A1 (fr) 2009-09-24
EA201070923A1 (ru) 2011-02-28
CL2009000264A1 (es) 2010-04-09
UY31640A1 (es) 2009-08-31
MY150776A (en) 2014-02-28
KR20100137442A (ko) 2010-12-30
MX2010008653A (es) 2011-03-04
US8304440B2 (en) 2012-11-06
AU2009227092B2 (en) 2014-08-07
PT2252286E (pt) 2011-12-07
UA99510C2 (ru) 2012-08-27
EP2252286A2 (de) 2010-11-24
EP2252286B1 (de) 2011-08-24
IL207442A0 (en) 2010-12-30
US20110160254A1 (en) 2011-06-30
HK1152892A1 (en) 2012-03-16
TW201000098A (en) 2010-01-01
FR2926993A1 (fr) 2009-08-07
CO6300843A2 (es) 2011-07-21

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