AP1707A - Contraceptive medicament based on a progesterone and an oestrogen and method for producing the same. - Google Patents
Contraceptive medicament based on a progesterone and an oestrogen and method for producing the same.Info
- Publication number
- AP1707A AP1707A APAP/P/2002/002485A AP2002002485A AP1707A AP 1707 A AP1707 A AP 1707A AP 2002002485 A AP2002002485 A AP 2002002485A AP 1707 A AP1707 A AP 1707A
- Authority
- AP
- ARIPO
- Prior art keywords
- oestrogen
- progesterone
- producing
- same
- relates
- Prior art date
Links
- 239000003433 contraceptive agent Substances 0.000 title abstract 3
- 230000002254 contraceptive effect Effects 0.000 title abstract 3
- 239000000262 estrogen Substances 0.000 title abstract 2
- RJKFOVLPORLFTN-LEKSSAKUSA-N Progesterone Chemical compound C1CC2=CC(=O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H](C(=O)C)[C@@]1(C)CC2 RJKFOVLPORLFTN-LEKSSAKUSA-N 0.000 title 2
- 239000003814 drug Substances 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 229960003387 progesterone Drugs 0.000 title 1
- 239000000186 progesterone Substances 0.000 title 1
- 239000000203 mixture Substances 0.000 abstract 3
- VOXZDWNPVJITMN-ZBRFXRBCSA-N 17β-estradiol Chemical compound OC1=CC=C2[C@H]3CC[C@](C)([C@H](CC4)O)[C@@H]4[C@@H]3CCC2=C1 VOXZDWNPVJITMN-ZBRFXRBCSA-N 0.000 abstract 1
- 229930182833 estradiol Natural products 0.000 abstract 1
- 229960004911 nomegestrol Drugs 0.000 abstract 1
- -1 nomegestrol ester Chemical class 0.000 abstract 1
- 231100000252 nontoxic Toxicity 0.000 abstract 1
- 230000003000 nontoxic effect Effects 0.000 abstract 1
- 239000000583 progesterone congener Substances 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/30—Oestrogens
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Endocrinology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Gynecology & Obstetrics (AREA)
- Reproductive Health (AREA)
- Diabetes (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Steroid Compounds (AREA)
- Orthopedics, Nursing, And Contraception (AREA)
Abstract
The invention relates to the field of chemistry and more particularly, to that of therapeutic chemistry. The invention relates particularly to novel contraceptive compositions formed from a progestative agent and an oestrogen. The invention relates specifically to novel pharmaceutical contraceptive compositions characterised in that they contain, as active principles, a nomegestrol ester and oestradiol in combination or as a mixture with an inert, non-toxic, pharmaceutically acceptable vehicle which is suitable for oral administration.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/FR1999/002587 WO2001030355A1 (en) | 1999-10-25 | 1999-10-25 | Contraceptive medicine based on a progestational agent and an oestrogen and preparation method |
| PCT/FR2000/002952 WO2001030358A1 (en) | 1999-10-25 | 2000-10-24 | Contraceptive medicament based on a progesterone and an oestrogen and method for producing the same |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AP2002002485A0 AP2002002485A0 (en) | 2002-06-30 |
| AP1707A true AP1707A (en) | 2007-02-26 |
Family
ID=9542725
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| APAP/P/2002/002485A AP1707A (en) | 1999-10-25 | 2000-10-24 | Contraceptive medicament based on a progesterone and an oestrogen and method for producing the same. |
Country Status (21)
| Country | Link |
|---|---|
| EP (2) | EP2020236B1 (en) |
| JP (1) | JP5484646B2 (en) |
| KR (1) | KR100549625B1 (en) |
| CN (1) | CN1205936C (en) |
| AP (1) | AP1707A (en) |
| AU (1) | AU784478B2 (en) |
| BR (1) | BR0014952A (en) |
| CA (1) | CA2388857C (en) |
| CR (1) | CR6627A (en) |
| CZ (1) | CZ301982B6 (en) |
| ES (1) | ES2565688T3 (en) |
| HK (1) | HK1048600A1 (en) |
| HU (1) | HU230467B1 (en) |
| IL (2) | IL149141A0 (en) |
| MX (1) | MXPA02004083A (en) |
| NO (1) | NO330885B1 (en) |
| NZ (1) | NZ518308A (en) |
| OA (1) | OA12071A (en) |
| RU (1) | RU2258512C2 (en) |
| WO (2) | WO2001030355A1 (en) |
| ZA (1) | ZA200203399B (en) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2754179B1 (en) | 1996-10-08 | 1998-12-24 | Theramex | NOVEL HORMONONAL COMPOSITION AND ITS USE |
| WO2001030356A1 (en) | 1999-10-25 | 2001-05-03 | Laboratoire Theramex | Hormonal composition based on a progestational agent and an oestrogen and use thereof |
| FR2814074B1 (en) * | 2000-09-15 | 2003-03-07 | Theramex | NOVEL TOPICAL ESTRO-PROGESTIVE COMPOSITIONS WITH SYSTEMIC EFFECT |
| KR100975350B1 (en) * | 2002-11-29 | 2010-08-12 | 재단법인서울대학교산학협력재단 | Transformed cloned cows producing human lactoferricin and methods for producing the same |
| SV2006002165A (en) * | 2004-07-07 | 2006-05-09 | Wyeth Corp | CYCLICAL PROGESTINE REGIMES AND KITS REF. AM101677 |
| EP1893182B8 (en) * | 2005-05-26 | 2012-04-04 | Teva Women's Health, Inc. | Oral dosage forms comprising progesterone and method of making and using the same |
| CN103877059A (en) * | 2014-03-26 | 2014-06-25 | 邵娜 | Nomegestrol acetate tablet and preparation process thereof |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2754179A1 (en) * | 1996-10-08 | 1998-04-10 | Theramex | NOVEL HORMONONAL COMPOSITION AND USE THEREOF |
Family Cites Families (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4390531A (en) | 1981-08-10 | 1983-06-28 | Syntex Pharmaceuticals International Ltd. | Method of contraception using peak progestogen dosage |
| US4921843A (en) | 1988-10-20 | 1990-05-01 | Pasquale Samuel A | Contraception system and method |
| US4628051A (en) | 1983-09-26 | 1986-12-09 | Ortho Pharmaceutical Corporation | Triphasic oral contraceptive |
| IE61236B1 (en) | 1986-07-15 | 1994-10-19 | American Home Prod | Combination dosage form for pre-menopausal women |
| ATE209919T1 (en) | 1987-09-24 | 2001-12-15 | Jencap Res Ltd | CONTRACEPT PACKS CONTAINING ESTROGEN AND PROGESTIN |
| IE71203B1 (en) | 1990-12-13 | 1997-02-12 | Akzo Nv | Low estrogen oral contraceptives |
| IE62665B1 (en) | 1990-12-17 | 1995-02-22 | Akzo Nv | Contraceptive regimen |
| US5532416A (en) | 1994-07-20 | 1996-07-02 | Monsanto Company | Benzoyl derivatives and synthesis thereof |
| DE4344462C2 (en) | 1993-12-22 | 1996-02-01 | Schering Ag | Composition for contraception |
| FR2737411B1 (en) * | 1995-08-01 | 1997-10-17 | Theramex | NOVEL HORMONAL DRUGS AND THEIR USE FOR CORRECTING ESTROGENIC DEFICIENCIES |
| DE19529767A1 (en) | 1995-08-12 | 1997-02-13 | Huels Chemische Werke Ag | Amphiphilic compounds with several hydrophilic and hydrophobic groups based on amino succinic acid derivatives |
| US5902914A (en) | 1995-08-14 | 1999-05-11 | Alliedsignal Inc. | Process for the preparation of halogenated alkanes |
| AUPN479995A0 (en) | 1995-08-15 | 1995-09-07 | Leon Kruss Technology Pty Limited | Lightweight cementitious composition |
| US5654494A (en) | 1995-08-18 | 1997-08-05 | Alliedsignal Inc. | Process for the manufacture of 1,1,1,2-tetrafluoroethane |
| US5530167A (en) | 1995-08-21 | 1996-06-25 | Eastman Chemical Company | Process for the preparation of 1,4-butenediol |
| DE19536742A1 (en) | 1995-10-02 | 1997-04-03 | Teves Gmbh Alfred | Wiper blade for a windshield wiper device of a vehicle |
| DE19536744A1 (en) | 1995-10-02 | 1997-04-03 | Teves Gmbh Alfred | Wiper blade with interchangeable wiper rubber for a vehicle wiper |
| DE19536745A1 (en) | 1995-10-02 | 1997-04-03 | Teves Gmbh Alfred | Wiper blade for a windshield wiper device of a vehicle, in particular a motor vehicle |
| DE29515703U1 (en) | 1995-10-02 | 1996-02-08 | Föhl, Artur, 73614 Schorndorf | Rotary drive device for a belt tensioner |
| WO1997012785A1 (en) | 1995-10-02 | 1997-04-10 | Nsk Ltd. | Seat belt retractor |
| EP0770338B1 (en) | 1995-10-23 | 2002-09-25 | Honda Access Corp. | Cap body of a helmet |
| DE19540253C2 (en) | 1995-10-28 | 1998-06-04 | Jenapharm Gmbh | Multi-phase preparation for contraception based on natural estrogens |
| DE19549264A1 (en) | 1995-12-23 | 1997-06-26 | Schering Ag | Contraception procedure and kit |
| AU2815897A (en) | 1996-05-08 | 1997-11-26 | American Home Products Corporation | Oral contraceptive |
| GB9621990D0 (en) | 1996-10-22 | 1996-12-18 | Scotia Pharma Ltd | Use |
| DE19705229C2 (en) | 1997-02-12 | 1999-04-15 | Hesch Rolf Dieter Prof Dr Med | Use of three hormonal components for hormonal contraception for the treatment and / or prophylaxis of tumors of the mammary glands |
| US5898032A (en) * | 1997-06-23 | 1999-04-27 | Medical College Of Hampton Roads | Ultra low dose oral contraceptives with less menstrual bleeding and sustained efficacy |
| ATE279198T1 (en) | 1997-08-27 | 2004-10-15 | Ortho Mcneil Pharm Inc | COMBINATIONS OF ENDOMETRUM-SPAREING PROGESTAGENS AND ENDOMETRUM ATROPHIZING PROGESTAGENS WITH ESTROGENS, IN ORAL CONTRACEPTION |
| DE19739916C2 (en) | 1997-09-11 | 2001-09-13 | Hesch Rolf Dieter | Use of a combination of a progestogen and an estrogen for the continuous inhibition of ovulation and possibly simultaneous treatment and / or prophylaxis of tumors of the mammary glands |
| JP2001516720A (en) * | 1997-09-12 | 2001-10-02 | アメリカン・ホーム・プロダクツ・コーポレイション | Oral contraceptive formulation having progestin / estrogen first phase and progestin second phase |
-
1999
- 1999-10-25 WO PCT/FR1999/002587 patent/WO2001030355A1/en active Application Filing
-
2000
- 2000-10-24 EP EP08168565.3A patent/EP2020236B1/en not_active Expired - Lifetime
- 2000-10-24 CN CNB008147868A patent/CN1205936C/en not_active Expired - Lifetime
- 2000-10-24 WO PCT/FR2000/002952 patent/WO2001030358A1/en not_active Application Discontinuation
- 2000-10-24 CZ CZ20021426A patent/CZ301982B6/en not_active IP Right Cessation
- 2000-10-24 CA CA2388857A patent/CA2388857C/en not_active Expired - Lifetime
- 2000-10-24 BR BR0014952-7A patent/BR0014952A/en not_active Application Discontinuation
- 2000-10-24 MX MXPA02004083A patent/MXPA02004083A/en active IP Right Grant
- 2000-10-24 EP EP00971488A patent/EP1227815A1/en not_active Withdrawn
- 2000-10-24 HK HK03100876.6A patent/HK1048600A1/en unknown
- 2000-10-24 ES ES08168565.3T patent/ES2565688T3/en not_active Expired - Lifetime
- 2000-10-24 AP APAP/P/2002/002485A patent/AP1707A/en active
- 2000-10-24 AU AU10335/01A patent/AU784478B2/en not_active Expired
- 2000-10-24 NZ NZ518308A patent/NZ518308A/en not_active IP Right Cessation
- 2000-10-24 KR KR1020027005258A patent/KR100549625B1/en not_active Expired - Lifetime
- 2000-10-24 OA OA1200200118A patent/OA12071A/en unknown
- 2000-10-24 JP JP2001532776A patent/JP5484646B2/en not_active Expired - Lifetime
- 2000-10-24 HU HUP0203443A patent/HU230467B1/en unknown
- 2000-10-24 IL IL14914100A patent/IL149141A0/en active IP Right Grant
- 2000-10-24 RU RU2002113654/15A patent/RU2258512C2/en active
-
2002
- 2002-04-15 IL IL149141A patent/IL149141A/en active Protection Beyond IP Right Term
- 2002-04-24 CR CR6627A patent/CR6627A/en not_active Application Discontinuation
- 2002-04-25 NO NO20021948A patent/NO330885B1/en not_active IP Right Cessation
- 2002-04-29 ZA ZA200203399A patent/ZA200203399B/en unknown
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2754179A1 (en) * | 1996-10-08 | 1998-04-10 | Theramex | NOVEL HORMONONAL COMPOSITION AND USE THEREOF |
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