ZA842801B - Ultrasound contrast agent containing microparticles and gas micro-bubbles - Google Patents

Ultrasound contrast agent containing microparticles and gas micro-bubbles

Info

Publication number
ZA842801B
ZA842801B ZA842801A ZA842801A ZA842801B ZA 842801 B ZA842801 B ZA 842801B ZA 842801 A ZA842801 A ZA 842801A ZA 842801 A ZA842801 A ZA 842801A ZA 842801 B ZA842801 B ZA 842801B
Authority
ZA
South Africa
Prior art keywords
bubbles
contrast agent
agent containing
containing microparticles
ultrasound contrast
Prior art date
Application number
ZA842801A
Inventor
Jurgen Hilmann
Lothar Lange
Ingfried Zimmermann
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of ZA842801B publication Critical patent/ZA842801B/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/22—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
    • A61K49/222—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
    • A61K49/223—Microbubbles, hollow microspheres, free gas bubbles, gas microspheres
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/39—Markers, e.g. radio-opaque or breast lesions markers
    • A61B2090/3925—Markers, e.g. radio-opaque or breast lesions markers ultrasonic

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Radiology & Medical Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physics & Mathematics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Acoustics & Sound (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Cosmetics (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Investigating Or Analyzing Materials By The Use Of Ultrasonic Waves (AREA)
  • Fire-Detection Mechanisms (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
  • Manufacturing Of Micro-Capsules (AREA)

Abstract

1. Contrast medium containing microparticles and gas bubbles for ultrasound diagnostics, characterised in that it contains microparticles of a solid surface-active substance, optionally in combination with microparticles of a non-surface-active solid, in a liquid carrier.
ZA842801A 1983-04-15 1984-04-13 Ultrasound contrast agent containing microparticles and gas micro-bubbles ZA842801B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3313946A DE3313946A1 (en) 1983-04-15 1983-04-15 MICROPARTICLES AND GAS BUBBLES CONTAINING ULTRASONIC CONTRASTING AGENTS

Publications (1)

Publication Number Publication Date
ZA842801B true ZA842801B (en) 1984-11-28

Family

ID=6196665

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA842801A ZA842801B (en) 1983-04-15 1984-04-13 Ultrasound contrast agent containing microparticles and gas micro-bubbles

Country Status (12)

Country Link
EP (1) EP0122624B1 (en)
JP (1) JPS59205328A (en)
AT (1) ATE36958T1 (en)
AU (1) AU566928B2 (en)
CA (1) CA1239092A (en)
DE (2) DE3313946A1 (en)
DK (1) DK165171C (en)
FI (1) FI81264C (en)
IE (1) IE57272B1 (en)
NO (1) NO161356C (en)
NZ (1) NZ207853A (en)
ZA (1) ZA842801B (en)

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US5137928A (en) * 1990-04-26 1992-08-11 Hoechst Aktiengesellschaft Ultrasonic contrast agents, processes for their preparation and the use thereof as diagnostic and therapeutic agents
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GB9200387D0 (en) * 1992-01-09 1992-02-26 Nycomed As Improvements in or relating to contrast agents
GB9200388D0 (en) * 1992-01-09 1992-02-26 Nycomed As Improvements in or relating to contrast agents
IL104084A (en) 1992-01-24 1996-09-12 Bracco Int Bv Long-lasting aqueous suspensions of pressure-resistant gas-filled microvesicles their preparation and contrast agents consisting of them
HU225495B1 (en) * 1993-12-15 2007-01-29 Bracco Research Sa Gas mixtures useful as ultrasound contrast media
DE4406474A1 (en) * 1994-02-23 1995-08-24 Schering Ag Gas-containing microparticles, agents containing them, their use in ultrasound diagnostics, and methods for producing the particles and agents
DE19510690A1 (en) 1995-03-14 1996-09-19 Schering Ag Polymeric nano- and / or microparticles, processes for their production, and use in medical diagnostics and therapy
DE19543077C2 (en) * 1995-11-13 1997-10-16 Schering Ag Use of gas-containing metal complexes as ultrasound contrast agent
DE19602930A1 (en) * 1996-01-18 1997-07-24 Schering Ag Porous matrices made of low molecular weight substances for the generation of stable gas bubble suspensions, their use as ultrasound contrast agents and processes for their production
DE19813174A1 (en) * 1998-03-25 1999-05-27 Schering Ag Gas-filled microparticles, used for administering biologically active substances
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US6254852B1 (en) 1999-07-16 2001-07-03 Dupont Pharmaceuticals Company Porous inorganic targeted ultrasound contrast agents
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Also Published As

Publication number Publication date
IE840835L (en) 1984-10-15
AU2680584A (en) 1984-10-18
NO841489L (en) 1984-10-16
EP0122624B1 (en) 1988-09-07
JPS59205328A (en) 1984-11-20
FI81264B (en) 1990-06-29
FI81264C (en) 1990-10-10
DE3473828D1 (en) 1988-10-13
CA1239092A (en) 1988-07-12
IE57272B1 (en) 1992-07-01
DK78984A (en) 1984-10-16
AU566928B2 (en) 1987-11-05
DK165171B (en) 1992-10-19
EP0122624A2 (en) 1984-10-24
DK165171C (en) 1993-03-01
EP0122624A3 (en) 1986-11-20
FI841462A0 (en) 1984-04-12
ATE36958T1 (en) 1988-09-15
DK78984D0 (en) 1984-02-20
JPH0425934B2 (en) 1992-05-06
NO161356B (en) 1989-05-02
DE3313946A1 (en) 1984-10-18
FI841462A (en) 1984-10-16
NZ207853A (en) 1988-01-08
NO161356C (en) 1989-08-09

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