WO2003030706A2 - Device for introducing into hollow organs of the body - Google Patents

Device for introducing into hollow organs of the body Download PDF

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Publication number
WO2003030706A2
WO2003030706A2 PCT/EP2002/011242 EP0211242W WO03030706A2 WO 2003030706 A2 WO2003030706 A2 WO 2003030706A2 EP 0211242 W EP0211242 W EP 0211242W WO 03030706 A2 WO03030706 A2 WO 03030706A2
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WO
WIPO (PCT)
Prior art keywords
measuring device
measuring
blood
hollow body
pressure
Prior art date
Application number
PCT/EP2002/011242
Other languages
German (de)
French (fr)
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WO2003030706A3 (en
Inventor
Werner Schregel
Original Assignee
Werner Schregel
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Werner Schregel filed Critical Werner Schregel
Priority to EP02782853A priority Critical patent/EP1434519A2/en
Priority to JP2003533745A priority patent/JP2005504599A/en
Priority to AU2002346970A priority patent/AU2002346970A1/en
Priority to US10/492,278 priority patent/US20050020890A1/en
Publication of WO2003030706A2 publication Critical patent/WO2003030706A2/en
Publication of WO2003030706A3 publication Critical patent/WO2003030706A3/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0082—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes
    • A61B5/0084—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes for introduction into the body, e.g. by catheters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/021—Measuring pressure in heart or blood vessels
    • A61B5/0215—Measuring pressure in heart or blood vessels by means inserted into the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/026—Measuring blood flow
    • A61B5/0265—Measuring blood flow using electromagnetic means, e.g. electromagnetic flowmeter
    • A61B5/027—Measuring blood flow using electromagnetic means, e.g. electromagnetic flowmeter using catheters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A61B5/1459—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters invasive, e.g. introduced into the body by a catheter
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/026—Measuring blood flow
    • A61B5/0275—Measuring blood flow using tracers, e.g. dye dilution
    • A61B5/028—Measuring blood flow using tracers, e.g. dye dilution by thermo-dilution

Definitions

  • the invention relates to a device for insertion into hollow body organs, in particular in blood vessels, consisting of an essentially elongated instrument with at least one measuring device located in an end of the device which is closed in the region of the end of the device inserted into the hollow body organ, in particular the bloodstream.
  • Known devices are designed as catheters and are used to dispense liquids in hollow body organs such. B. to inject blood streams or to take samples from hollow body organs. Special instruments are required for insertion into the hollow organ of the body, since the catheters are, for example, not suitable for penetrating tissue layers due to their flexible design.
  • a measuring device is partially provided in the catheters. Using this known measuring device, amounts of air in liquids, such as. B. in blood. If the operator wants z. B. get more information about the composition of the blood or the amount of air detected, the correspondingly detected gas or blood must be extracted. The surgeon also receives none, for example, using the previously known device further information. For example, if the surgeon wants to get more information about blood pressure, he has to use other instruments, some of which have to be inserted into the patient's body.
  • the object of the invention is therefore to improve and specify a previously known device that is more versatile.
  • a suitable measuring device for measuring the composition and / or the properties of the blood.
  • the body's own laboratory values e.g. Hemoglobin, oxygen saturation, electrolytes, blood gases, viscosity are determined.
  • concentration of gases or chemicals e.g. Medications or indicator dyes to be determined so that when the values fall below certain values, the missing substances can be added in an optimal dosage that is tailored to the patient to be treated.
  • the measuring device can be inserted in a channel closed at the end, it does not come into contact with the medium to be examined, such as, for. B. blood and is recyclable. After use, the measuring device can be easily pulled out of the inlet or the channel and simply inserted into a new device.
  • the measuring device can be designed as an optical measuring device and the instrument can be made of a material that is transparent to the measurement of optical radiation and enables an optical measurement, at least in the area of the measuring device.
  • the Instrument for example, have a window that enables optical detection. It is Z. B. also possible that the entire instrument consists of an optically transparent material.
  • the instrument can have a semi-permeable membrane in the measuring range.
  • a semi-permeable membrane allows ions to pass through for the examination of the body's laboratory values; however, the passage of blood, proteins, infectious agents or other substances is prevented, so that the measuring device is nevertheless recyclable.
  • measuring devices are conceivable, consisting of a transmitter and a receiver, it being possible to draw conclusions about the substance to be examined on the basis of the refraction behavior of emitted and received light beams.
  • Optical measuring devices are also conceivable in which light beams of different wavelengths are emitted and at least partially reflected, so that conclusions about substances in the blood are possible.
  • Measuring devices suitable for spectroscopy are also conceivable.
  • the measuring device can also be integrated in a chip, designed as a chip or connected to it.
  • a suitable measuring device can be provided for measuring the temperature of the blood flowing in the bloodstream and / or values that can be determined by temperature measurement (s), in particular the flow rate.
  • the instrument consists of a material that enables temperature measurement.
  • this measuring device can be used together with a measuring device.
  • device for measuring the composition and / or the properties of the blood can be provided in a device according to the invention. Since the measuring device can be inserted in a channel closed at the end, it does not come into contact with the medium to be examined, such as, for. B. blood and is recyclable. After use, the measuring device can be easily pulled out of the insertion and can easily be inserted into a new device.
  • the measuring device can be designed as a temperature measuring device and / or as a heat flow sensor.
  • the temperature measuring device consists, for example, of temperature sensors arranged at a distance from one another, a temperature sensor being spaced apart from the medium to be measured via an additional insulating material.
  • the measured difference allows conclusions to be drawn about the flow rate, which in turn provides an indication of the blood flow to the organs. In this way, the volume can also be determined.
  • B. is promoted by the heart within a certain time interval.
  • Thermocouples for example, can be used as the temperature measuring device.
  • the measuring device can also be integrated in a chip, designed as a chip or connected to it.
  • a suitable measuring device can be provided for measuring hemodynamic parameters of the blood and / or values that can be determined by pressure measurement (s).
  • This measuring device can be used together with a measuring device for measuring the The composition and / or the properties of the blood and / or a measuring device for measuring the temperature and / or values which can be determined by temperature measurement can be provided in the device according to the invention. Since the measuring device can be inserted in a channel closed at the end, it does not come into contact with the medium to be examined, such as, for. B. blood and is recyclable. After use, the measuring device can be easily pulled out of the insertion and can easily be inserted into a new device.
  • Hemodynamic parameters are understood to mean, for example, blood pressure, cardiac rhythm or cardiac output.
  • Particles in the blood such as e.g. B. embolisms, blood clots, bone fragments, bone cement or fats can be determined.
  • conclusions can be drawn about the flow rate and the cardiac output by measuring such quantities.
  • the measuring device can be designed for the measurement of pressure, in particular of reflected sound pressure of a sound generator, and the instrument can have an area that transmits pressure at least in the area of the measuring device.
  • the pressure measuring device can be designed as a pressure sensor, in particular a piezo element. However, pressure transducers operating on a magnetic basis or pressure transducers designed as microphones are also conceivable.
  • the pressure measuring device can also be designed as an ultrasound probe. It is possible for a plurality of such measuring devices to be arranged at a distance from one another in the longitudinal direction. In this case, one makes use of the so-called "Doppler effect", in which the frequency change between the waves emitted by the receiver and received by the receiver is determined.
  • the measuring device can also be integrated in a chip, designed as a chip or connected to it.
  • the data determined or measured by the respective measuring device and / or the chip can be passed in different ways to a control and display device located outside the device, so that the user can record the data relevant to him. In the simplest embodiment, this is done via a cable connection. Transmission via radio or infrared is also conceivable. If a chip is provided, a memory is advantageous since the data can then also be archived. It is also possible that - if the data does not have to be read simultaneously - it can only be called up after the treatment and then analyzed.
  • a device that generates and sends out pulses preferably cardiac pacemaker pulses, can also be provided in the instrument.
  • the device can be integrated in a chip, designed as a chip or connected to it.
  • at least one infusion or suction channel the end region of which in the bloodstream has at least one opening, can be provided. This proves to be advantageous since liquids can then be aspirated via the instrument or drugs or solutions can be injected into the hollow body in question.
  • the device is rigid and has a tip at the end to be inserted into the hollow body organ.
  • the instrument according to the invention is also suitable for tissue layers such. B. to penetrate the skin so that it does not require a separate instrument for inserting the device according to the invention into the hollow body to be examined.
  • the closed end channel or another closed channel can be used for therapeutic temperature influencing, for. B. by means of an introduced heating and / or cooling element or introduction of a particularly circulating tempering medium.
  • the cooling element can, for example, be brought to the desired temperature before insertion.
  • a temperature control medium is advantageously circulated in the temperature control element, so that the temperature control medium can be continuously brought to the desired temperature by a corresponding temperature control device.
  • the temperature control medium it is also possible for the temperature control medium to be fed directly into the channel.
  • a partition wall extending along the channel is preferably provided in the channel.
  • the partition preferably has a recess in the region of the closed end, so that the channel has an approximately U-shaped course and thus the temperature control medium, such as z. B. a hot or cold saline solution can circulate.
  • the instrument according to the invention is suitable for both venous and arterial use.
  • the instrument according to the invention can also be used for examination in the heart.
  • FIG. 1 is a side view of a device according to the invention
  • FIG. 2 shows a section through a device with an infusion or suction channel and at least one integrated measuring device
  • FIG 3 shows a section through a device with an infusion or suction channel and a channel closed at the end, in which at least one recyclable measuring device is inserted, and
  • FIG. 4 shows a section through a device with an infusion or suction channel and two channels closed at the ends, in each of which at least one measuring device is inserted.
  • FIG. 1 shows a device 1, which consists of an essentially tubular instrument.
  • the device 1 is a catheter which is inserted into a bloodstream (not shown), one end 2, with which the device 1 is inserted into a bloodstream, being designed in the manner of a truncated cone.
  • Measuring devices 3 are provided at a distance from the end 2 of the device 1.
  • the measuring devices 3 are advantageously arranged in such a way that the radiation angles - if they are provided, for example, for measuring the gas and / or drug concentration - overlap so that the entire vascular volume of the bloodstream can be monitored.
  • measuring devices 3 there are a total of three measuring devices 3 in the device 1, advantageously a measuring device for measuring the composition and / or properties of the blood, a measuring device for measuring the temperature and / or values that can be determined by temperature measurement, and a measuring device for measuring hemodynamic parameters and / or of values that can be determined by pressure measurement.
  • the device 1 Since the device 1 is simultaneously designed as a catheter, there are lateral openings 4 between the measuring devices 3 and the end 2 of the device 1 and in the area of the end 2, an end opening 5 is provided which is connected to an infusion or suction channel 6, as shown in FIG. 2.
  • the other end of the device 1 is connected to a conventional infusion or suction device, not shown, for the infusion or suction channel 6, and to a control and display device, also not shown, for the measuring devices 3.
  • the device 1 Before an operative intervention, the device 1 is inserted with its end 2 into a bloodstream (not shown) and placed at the desired examination site. Via the openings 4 and 5, substances such as. B. drugs, injected or aspirated samples, while measurements can be made on the measuring device 3 at the same time.
  • FIG. 2 shows a variant of the device 1 according to the invention, in which the measuring devices 3 are permanently integrated in the device 1.
  • the measuring device 3 shown by way of example in FIG. 2 consists of a receiver and a transmitter, which are arranged at an angle to one another.
  • the waves emitted by the transmitter are reflected by the liquid or any air bubbles present and received again by the receiver.
  • the reflected medium i. H. Liquid or air bubbles
  • differences in the frequency of the transmitted and received waves so that by means of this technique, e.g. B. particles in the blood such. B. bone fragments can be detected.
  • the measuring devices 3 shows an embodiment of the device 1 in which the measuring devices 3 are located in a device 1 arranged end closed channel 7 are located. Since the channel 7 is closed at the end, the measuring devices 3 arranged and displaceable therein do not come into contact with the liquid to be monitored and flowing around the device 1. After the operation, the measuring devices 3 are pulled out of the channel (7) of the device 1 and can be used in a new device 1 and thus reused without the need for expensive sterilization. Here too, the infusion or suction channel 6 is arranged in the other half of the device 1.
  • the various required measuring devices 3 can optionally be introduced in the device 1 with a channel 7, so that each device 1 can be optimally adapted to the specific application.
  • the infusion or suction channel 6 is arranged in the center, with channels 7 closed on both ends being provided on both sides of the infusion or suction channel. Measuring devices 3 are introduced into these channels 7. No further explanation is required that several measuring devices 3 can be provided in each channel 7.
  • a pulse generating and emitting device can be provided in the channel 7. This is useful, for example, in cardiac surgery in which cardiac activity is to be stabilized.
  • the device 1 shown in FIGS. 1 to 4 is a catheter. It goes without saying lent that the device 1 can also be designed as a needle, in which case the end 2 is pointed. In such an embodiment, the device 1 is also suitable for piercing tissue.
  • drugs can be added in doses, while the drug concentration in the relevant body organ is determined at the same time.
  • the device 1 is designed as a needle, no lateral openings 4 are required.

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  • Health & Medical Sciences (AREA)
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Abstract

The invention relates to a device for introducing into hollow organs of the body, in particular into blood vessels. Said device consists of a substantially longitudinal instrument comprising a measuring device that is located in a closed channel in the vicinity of the device end that is introduced into the hollow organ of the body, in particular the blood vessel. The aim of the invention is to improve a device known per se and to widen its range of application. To achieve this, the device is provided with a measuring device that is suitable for measuring the composition and/or the characteristics of the blood, and/or a measuring device that is suitable for measuring the temperature of the blood flowing in the blood vessel and/or values that can be determined by temperature measurements, in particular the flow rate, and/or a measuring device for measuring haemodynamic parameters of the blood and/or values that can be determined by pressure measurements.

Description

Professor Dr. med. Werner Schregel, Heidedyk 44, 47802 KrefeldProfessor Dr. med. Werner Schregel, Heidedyk 44, 47802 Krefeld
Einrichtung zum Einführen in KörperhohlorganeDevice for insertion into hollow body organs
Die Erfindung betrifft eine Einrichtung zum Einführen in Körperhohlorgane, insbesondere in Blutbahnen, bestehend aus einem im wesentlichen länglich ausgebildeten Instrument mit zumindest einer in einem im Bereich des in das Körperhohlorgan, insbesondere die Blutbahn, eingeführten Endes der Einrichtung geschlossenen Kanal befindlichen Messeinrichtung .The invention relates to a device for insertion into hollow body organs, in particular in blood vessels, consisting of an essentially elongated instrument with at least one measuring device located in an end of the device which is closed in the region of the end of the device inserted into the hollow body organ, in particular the bloodstream.
Bekannte Einrichtungen sind als Katheter ausgebildet und werden dazu verwendet, Flüssigkeiten in Körperhohlorgane wie z. B. Blutbahnen zu injizieren oder Proben aus Körperhohlorganen zu entnehmen. Zum Einführen in das Körperhohlorgan sind spezielle Instrumente erforderlich, da die Katheter aufgrund ihrer flexiblen Ausbildung beispielsweise nicht zum Durchdringen von Gewebeschichten geeignet sind. Teilweise ist in den Kathetern eine Messeinrichtung vorgesehen. Mittels dieser bekannten Messeinrichtung können Luftmengen in Flüssigkeiten, wie z. B. in Blut, detektiert werden. Will der Operateur z. B. nähere Informationen über die Zusammensetzung des Blutes oder auch der detektierten Luftmenge erhalten, muss das entsprechend detektierte Gas oder das Blut abgesaugt werden. Auch erhält der Operateur mittels der vorbekannten Einrichtung beispielsweise keine weitergehenden Informationen. Will der Operateur beispielsweise nähere Informationen über den Blutdruck erhalten, muss er sich weiterer Instrumente bedienen, die teilweise zusätzlich in den Körper des Patienten eingeführt werden müssen.Known devices are designed as catheters and are used to dispense liquids in hollow body organs such. B. to inject blood streams or to take samples from hollow body organs. Special instruments are required for insertion into the hollow organ of the body, since the catheters are, for example, not suitable for penetrating tissue layers due to their flexible design. A measuring device is partially provided in the catheters. Using this known measuring device, amounts of air in liquids, such as. B. in blood. If the operator wants z. B. get more information about the composition of the blood or the amount of air detected, the correspondingly detected gas or blood must be extracted. The surgeon also receives none, for example, using the previously known device further information. For example, if the surgeon wants to get more information about blood pressure, he has to use other instruments, some of which have to be inserted into the patient's body.
Aufgabe der Erfindung ist es daher, eine vorbekannte Einrichtung dahingehend zu verbessern und anzugeben, die vielseitiger einsetzbar ist.The object of the invention is therefore to improve and specify a previously known device that is more versatile.
Diese Aufgabe wird dadurch gelöst, dass zur Messung der Zusammensetzung und/oder der Eigenschaften des Blutes eine geeignete Messeinrichtung vorgesehen ist . Mittels einer solchen Messeinrichtung können beispielsweise körpereigene Laborwerte, wie z.B. Hämoglobin, SauerstoffSättigung, Elektrolyte, Blutgase, Viskosität, ermittelt werden. Es ist auch möglich, die Konzentration von Gasen oder chemischen Stoffen, wie z.B. Medikamenten oder Indikatorfarbstoffen, zu ermitteln, so dass bei Unterschreiten gewisser Werte die fehlenden Substanzen in optimalen auf den zu behandelnden Patienten abgestimmten Dosierung zugegeben werden können. Da die Messeinrichtung in einem endseitig geschlossenen Kanal einführbar ist, kommt sie nicht in Kontakt mit dem zu untersuchenden Medium, wie z. B. Blut und ist insoweit wiederverwertbar. Nach dem Gebrauch kann die Messeinrichtung aus der Einführung bzw. dem Kanal problemlos herausgezogen werden und einfach in eine neue Einrichtung eingeführt werden.This object is achieved in that a suitable measuring device is provided for measuring the composition and / or the properties of the blood. With such a measuring device, for example, the body's own laboratory values, e.g. Hemoglobin, oxygen saturation, electrolytes, blood gases, viscosity are determined. It is also possible to adjust the concentration of gases or chemicals, e.g. Medications or indicator dyes to be determined so that when the values fall below certain values, the missing substances can be added in an optimal dosage that is tailored to the patient to be treated. Since the measuring device can be inserted in a channel closed at the end, it does not come into contact with the medium to be examined, such as, for. B. blood and is recyclable. After use, the measuring device can be easily pulled out of the inlet or the channel and simply inserted into a new device.
Die Messeinrichtung kann als optische Messeinrichtung ausgebildet sein und das Instrument kann zumindest im Bereich der Messeinrichtung aus einem für die zur Messung optischer Strahlung durchlässigen und eine optische Messung ermöglichenden Material bestehen. Hierzu kann das Instrument beispielsweise ein Fenster aufweisen, das eine optische Erfassung ermöglicht. Es ist z. B. auch möglich, dass das ganze Instrument aus einem optisch durchlässigen Material besteht .The measuring device can be designed as an optical measuring device and the instrument can be made of a material that is transparent to the measurement of optical radiation and enables an optical measurement, at least in the area of the measuring device. For this, the Instrument, for example, have a window that enables optical detection. It is Z. B. also possible that the entire instrument consists of an optically transparent material.
Alternativ kann das Instrument im Messbereich eine semi- permeable Membran aufweisen. Eine solche Membran ermöglicht zwar ein Passieren von Ionen für die Untersuchung der körpereigenen Laborwerte; jedoch wird ein Durchtritt von Blut, Eiweißen, Infektionserregern oder anderen Stoffen verhindert, so dass die Messeinrichtung gleichwohl wiederverwertbar ist .Alternatively, the instrument can have a semi-permeable membrane in the measuring range. Such a membrane allows ions to pass through for the examination of the body's laboratory values; however, the passage of blood, proteins, infectious agents or other substances is prevented, so that the measuring device is nevertheless recyclable.
Denkbar sind beispielsweise Messeinrichtungen, bestehend aus einem Sender und einem Empfänger, wobei aufgrund des Brechungsverhalten von ausgesendeten und empfangenen Lichtstrahlen Rückschlüsse auf den zu untersuchenden Stoff gemacht werden können. Auch sind optische Messeinrichtungen denkbar, bei denen Lichtstrahlen unterschiedlicher Wellenlänge ausgesandt und zumindest partiell reflektiert werden, so dass Rückschlüsse auf im Blut befindliche Stoffe möglich sind. Auch Spektroskopie geeignete Messeinrichtungen sind denkbar. Die Messeinrichtung kann auch in einen Chip integriert, als Chip ausgebildet bzw. mit diesem verbunden sein.For example, measuring devices are conceivable, consisting of a transmitter and a receiver, it being possible to draw conclusions about the substance to be examined on the basis of the refraction behavior of emitted and received light beams. Optical measuring devices are also conceivable in which light beams of different wavelengths are emitted and at least partially reflected, so that conclusions about substances in the blood are possible. Measuring devices suitable for spectroscopy are also conceivable. The measuring device can also be integrated in a chip, designed as a chip or connected to it.
Bei einem anderen Ausführungsbeispiel der Erfindung kann zur Messung der Temperatur des in der Blutbahn fließenden Blutes und/oder von durch Temperaturmessung (en) bestimmbaren Werten, insbesondere der Flussgeschwindigkeit, eine geeignete Messeinrichtung vorgesehen sein. Das Instrument besteht dabei zumindest im Messbereich aus einem Material, das eine Temperaturmessung ermöglicht. Selbstverständlich kann diese Messeinrichtung zusammen mit einer Messein- richtung zur Messung der Zusammensetzung und/oder der Eigenschaften des Blutes in einer erfindungsgemäßen Einrichtung vorgesehen sein. Da die Messeinrichtung in einem endseitig geschlossenen Kanal einführbar ist, kommt sie nicht in Kontakt mit dem zu untersuchenden Medium, wie z. B. Blut und ist insoweit wiederverwertbar. Nach dem Gebrauch kann die Messeinrichtung aus der Einführung problemlos herausgezogen werden und kann einfach in eine neue Einrichtung eingeführt werden.In another exemplary embodiment of the invention, a suitable measuring device can be provided for measuring the temperature of the blood flowing in the bloodstream and / or values that can be determined by temperature measurement (s), in particular the flow rate. At least in the measuring range, the instrument consists of a material that enables temperature measurement. Of course, this measuring device can be used together with a measuring device. device for measuring the composition and / or the properties of the blood can be provided in a device according to the invention. Since the measuring device can be inserted in a channel closed at the end, it does not come into contact with the medium to be examined, such as, for. B. blood and is recyclable. After use, the measuring device can be easily pulled out of the insertion and can easily be inserted into a new device.
Dabei kann die Messeinrichtung als Temperaturmesseinrichtung und/oder als Wärmeflusssensor ausgebildet sein.The measuring device can be designed as a temperature measuring device and / or as a heat flow sensor.
Sofern beispielsweise die Flussgeschwindigkeit gemessen werden soll, besteht die Temperaturmesseinrichtung beispielsweise aus im Abstand zueinander angeordneten Temperatursensoren, wobei ein Temperatursensor über einen zusätzlichen Isolierstoff von dem zu messenden Medium beabstandet ist. Die gemessene Differenz erlaubt Rückschlüsse auf die Flussgeschwindigkeit, die wiederum ein Hinweis auf die Durchblutung der Organe liefert. So kann auch das Volumen bestimmt werden, das z. B. innerhalb eines bestimmten Zeitintervalls vom Herzen gefördert wird. Als Temperaturmesseinrichtung können beispielsweise Thermoelemente eingesetzt werden.If, for example, the flow velocity is to be measured, the temperature measuring device consists, for example, of temperature sensors arranged at a distance from one another, a temperature sensor being spaced apart from the medium to be measured via an additional insulating material. The measured difference allows conclusions to be drawn about the flow rate, which in turn provides an indication of the blood flow to the organs. In this way, the volume can also be determined. B. is promoted by the heart within a certain time interval. Thermocouples, for example, can be used as the temperature measuring device.
Die Messeinrichtung kann auch in einen Chip integriert, als Chip ausgebildet bzw. mit diesem verbunden sein.The measuring device can also be integrated in a chip, designed as a chip or connected to it.
Bei einer weiteren Ausführungsform der Erfindung kann zur Messung hämodynamischer Parameter des Blutes und/oder von durch Druckmessung (en) bestimmbaren Werten eine geeignete Messeinrichtung vorgesehen sein. Diese Messeinrichtung kann zusammen mit einer Messeinrichtung zur Messung der Zusammensetzung und/oder der Eigenschaften des Blutes und/oder einer Messeinrichtung zur Messung der Temperatur und/oder von durch Temperaturmessung bestimmbaren Werten in der erfindungsgemäßen Einrichtung vorgesehen sein. Da die Messeinrichtung in einem endseitig geschlossenen Kanal einführbar ist, kommt sie nicht in Kontakt mit dem zu untersuchenden Medium, wie z. B. Blut und ist insoweit wiederverwertbar. Nach dem Gebrauch kann die Messeinrichtung aus der Einführung problemlos herausgezogen werden und kann einfach in eine neue Einrichtung eingeführt werden.In a further embodiment of the invention, a suitable measuring device can be provided for measuring hemodynamic parameters of the blood and / or values that can be determined by pressure measurement (s). This measuring device can be used together with a measuring device for measuring the The composition and / or the properties of the blood and / or a measuring device for measuring the temperature and / or values which can be determined by temperature measurement can be provided in the device according to the invention. Since the measuring device can be inserted in a channel closed at the end, it does not come into contact with the medium to be examined, such as, for. B. blood and is recyclable. After use, the measuring device can be easily pulled out of the insertion and can easily be inserted into a new device.
Unter hämodynamischen Parametern werden beispielsweise Blutdruck, Herzrhythmus oder Herzminutenvolumenstrom verstanden. Auch können durch eine solche Messeinrichtung im Blut befindliche Partikel, wie z. B. Embolien, Blutgerinsel, Knochensplitter, Knochenzement oder Fette bestimmt werden. Gleichzeitig können durch Messung derartiger Größen Rückschlüsse auf die Flussgeschwindigkeit und das Herzminutenvolumen gemacht werden.Hemodynamic parameters are understood to mean, for example, blood pressure, cardiac rhythm or cardiac output. Particles in the blood, such as e.g. B. embolisms, blood clots, bone fragments, bone cement or fats can be determined. At the same time, conclusions can be drawn about the flow rate and the cardiac output by measuring such quantities.
Die Messeinrichtung kann für die Messung von Druck, insbesondere von reflektiertem Schalldruck eines Schallerzeugers, ausgebildet sein und das Instrument kann zumindest im Bereich der Messeinrichtung einen eine Druckübertragung weitergebenden Bereich aufweisen.The measuring device can be designed for the measurement of pressure, in particular of reflected sound pressure of a sound generator, and the instrument can have an area that transmits pressure at least in the area of the measuring device.
Die Druckmesseinrichtung kann als Druckaufnehmer, insbesondere Piezoelement , ausgebildet sein. Es sind aber auch beispielsweise auf magnetischer Basis arbeitende Druckaufnehmer oder als Mikrofon ausgebildete Druckaufnehmer denkbar. Die Druckmesseinrichtung kann ebenfalls als Ultraschall- sonde ausgebildet sein. Dabei ist es möglich, dass mehrere derartiger Messeinrichtungen in Längsrichtung im Abstand zueinander angeordnet sind. In diesem Fall macht man sich den sogenannten "Dopplereffekt" zu nutzen, bei dem die Frequenzänderung zwischen den von dem Empfänger ausgestrahlten und von dem Empfänger empfangenen Wellen ermittelt wird.The pressure measuring device can be designed as a pressure sensor, in particular a piezo element. However, pressure transducers operating on a magnetic basis or pressure transducers designed as microphones are also conceivable. The pressure measuring device can also be designed as an ultrasound probe. It is possible for a plurality of such measuring devices to be arranged at a distance from one another in the longitudinal direction. In this case, one makes use of the so-called "Doppler effect", in which the frequency change between the waves emitted by the receiver and received by the receiver is determined.
Die Messeinrichtung kann auch in einen Chip integriert, als Chip ausgebildet bzw. mit diesem verbunden sein.The measuring device can also be integrated in a chip, designed as a chip or connected to it.
Die von der jeweiligen Messeinrichtung und/oder dem Chip ermittelten bzw. gemessenen Daten können auf unterschiedliche Weise an eine außerhalb der Einrichtung befindliche Steuer- und Anzeigeeinrichtung geleitet werden, so dass der Benutzer die für ihn relevanten Daten erfassen kann. In der einfachsten Ausführungsform erfolgt dies über eine Kabelverbindung. Eine Übertragung über Funk oder Infrarot ist ebenfalls denkbar. Sofern ein Chip vorgesehen ist, ist ein Speicher von Vorteil, da dann die Daten zusätzlich noch archiviert werden können. Ebenfalls ist es möglich, dass - sofern die Daten nicht simultan abgelesen werden müssen - diese erst nach der Behandlung abgerufen und dann analysiert werden können.The data determined or measured by the respective measuring device and / or the chip can be passed in different ways to a control and display device located outside the device, so that the user can record the data relevant to him. In the simplest embodiment, this is done via a cable connection. Transmission via radio or infrared is also conceivable. If a chip is provided, a memory is advantageous since the data can then also be archived. It is also possible that - if the data does not have to be read simultaneously - it can only be called up after the treatment and then analyzed.
Um ein erfindungsgemäßes Instrument beispielsweise auch zur Stabilisierung der Herzfrequenz bei Operationen einsetzen zu können, kann in dem Instrument zusätzlich eine Impulse, vorzugsweise Herzschrittmacherimpulse, erzeugende und aussendende Vorrichtung vorgesehen sein.In order to be able to use an instrument according to the invention for stabilizing the heart rate during operations, for example, a device that generates and sends out pulses, preferably cardiac pacemaker pulses, can also be provided in the instrument.
Dabei kann die Vorrichtung in einem Chip integriert, als Chip ausgebildet bzw. mit diesem verbunden sein. Zusätzlich kann zumindest ein Infusions- bzw. Absaugkanal, dessen in der Blutbahn befindlicher Endbereich zumindest eine Öffnung aufweist, vorgesehen sein. Dies erweist sich als vorteilhaft, da dann über das Instrument Flüssigkeiten abgesaugt bzw. Medikamente oder Lösungen in das betreffende Körperhohlorgan injiziert werden können.The device can be integrated in a chip, designed as a chip or connected to it. In addition, at least one infusion or suction channel, the end region of which in the bloodstream has at least one opening, can be provided. This proves to be advantageous since liquids can then be aspirated via the instrument or drugs or solutions can be injected into the hollow body in question.
Als zweckmäßig erweist sich, wenn die Einrichtung starr ausgebildet ist und an dem in das Körperhohlorgan einzuführenden Ende eine Spitze aufweist. Bei einer solchen Ausführungsform ist das erfindungsgemäße Instrument auch dafür geeignet, Gewebeschichten wie z. B. die Haut zu durchdringen, so dass es keines separaten Instrumentes zum Einführen der erfindungsgemäßen Einrichtung in das zu untersuchende Körperhohlorgan bedarf .It proves to be expedient if the device is rigid and has a tip at the end to be inserted into the hollow body organ. In such an embodiment, the instrument according to the invention is also suitable for tissue layers such. B. to penetrate the skin so that it does not require a separate instrument for inserting the device according to the invention into the hollow body to be examined.
Der endseitig geschlossen ausgebildete Kanal oder ein weiterer geschlossen ausgebildeter Kanal kann zur therapeutischen Temperaturbeeinflussung, z. B. mittels eines eingeführten Heiz- und/oder Kühlelementes oder Einbringen eines insbesondere zirkulierenden Temperiermediums, vorgesehen sein. Das Kühlelement kann beispielsweise vor dem Einführen auf die gewünschte Temperatur gebracht werden. Vorteilhafterweise wird in dem Temperierelement ein Temperiermedium in einem Kreislauf geführt, so dass das Temperiermedium durch eine entsprechende Temperiereinrichtung fortwährend auf die gewünschte Temperatur gebracht werden kann. Es ist aber auch möglich, dass das Temperiermedium direkt in den Kanal geleitet wird. In diesem Fall ist vorzugsweise in dem Kanal eine sich längs des Kanals erstreckende Trennwand vorgesehen. Die Trennwand weist vorzugsweise im Bereich des geschlossen ausgebildeten Endes eine Aussparung auf, so dass der Kanal einen in etwa U- förmigen Verlauf aufweist und so das Temperiermedium, wie z. B. eine heiße oder kalte kochsalzhaltige Lösung, zirkulieren kann.The closed end channel or another closed channel can be used for therapeutic temperature influencing, for. B. by means of an introduced heating and / or cooling element or introduction of a particularly circulating tempering medium. The cooling element can, for example, be brought to the desired temperature before insertion. A temperature control medium is advantageously circulated in the temperature control element, so that the temperature control medium can be continuously brought to the desired temperature by a corresponding temperature control device. However, it is also possible for the temperature control medium to be fed directly into the channel. In this case, a partition wall extending along the channel is preferably provided in the channel. The partition preferably has a recess in the region of the closed end, so that the channel has an approximately U-shaped course and thus the temperature control medium, such as z. B. a hot or cold saline solution can circulate.
Es bedarf keiner näheren Erläuterung, dass das erfindungs- gemäße Instrument sowohl zur venösen als auch zur arteriellen Verwendung geeignet ist. Selbstverständlich kann das erfindungsgemäße Instrument auch zur Untersuchung im Herzen eingesetzt werden.No further explanation is required that the instrument according to the invention is suitable for both venous and arterial use. Of course, the instrument according to the invention can also be used for examination in the heart.
Im Folgenden wird ein in den Zeichnungen dargestelltes Ausführungsbeispiel der Erfindung erläutert. Es zeigen:An exemplary embodiment of the invention illustrated in the drawings is explained below. Show it:
Fig. 1 eine Seitenansicht auf eine erfindungsgemäße Einrichtung,1 is a side view of a device according to the invention,
Fig. 2 einen Schnitt durch eine Einrichtung mit einem Infusions- bzw. Absaugkanal und zumindest einer integrierten Messeinrichtung,2 shows a section through a device with an infusion or suction channel and at least one integrated measuring device,
Fig. 3 einen Schnitt durch eine Einrichtung mit einem Infusions- bzw. Absaugkanal und einem endseitig geschlossenen Kanal, in dem zumindest eine wiederverwertbare Messeinrichtung eingeführt ist, und3 shows a section through a device with an infusion or suction channel and a channel closed at the end, in which at least one recyclable measuring device is inserted, and
Fig. 4 einen Schnitt durch eine Einrichtung mit einem Infusions- bzw. Absaugkanal und zwei endseitig geschlossenen Kanälen, in denen jeweils zumindest eine Messeinrichtung eingeführt ist .4 shows a section through a device with an infusion or suction channel and two channels closed at the ends, in each of which at least one measuring device is inserted.
In sämtlichen Zeichnungen werden für gleiche bzw. gleichartige Bauteile die gleichen Bezugszeichen verwendet. Fig. 1 zeigt eine Einrichtung 1, die aus einem im Wesentlichen rohrförmigen Instrument besteht. In dem dargestellten Ausführungsbeispiel handelt es sich bei der Einrichtung 1 um einen Katheter, der in eine nicht dargestellte Blutbahn eingeführt wird, wobei ein Ende 2, mit dem die Einrichtung 1 in eine Blutbahn eingeführt wird, kegelstumpfartig ausgebildet ist.The same reference numerals are used in all drawings for the same or similar components. 1 shows a device 1, which consists of an essentially tubular instrument. In the exemplary embodiment shown, the device 1 is a catheter which is inserted into a bloodstream (not shown), one end 2, with which the device 1 is inserted into a bloodstream, being designed in the manner of a truncated cone.
Im Abstand zum Ende 2 der Einrichtung 1 sind Messeinrichtungen 3 vorgesehen. Die Messeinrichtungen 3 sind vorteilhafterweise so angeordnet, dass die Abstrahlwinkel - sofern sie beispielsweise zur Messung der Gas- und/oder Medikamentenkonzentration vorgesehen sind - sich überlappen, damit das ganze Gefäßvolumen der Blutbahn überwacht werden kann.Measuring devices 3 are provided at a distance from the end 2 of the device 1. The measuring devices 3 are advantageously arranged in such a way that the radiation angles - if they are provided, for example, for measuring the gas and / or drug concentration - overlap so that the entire vascular volume of the bloodstream can be monitored.
In dem dargestellten Ausführungsbeispiel befinden sich in der Einrichtung 1 insgesamt drei Messeinrichtungen 3, wobei vorteilhafterweise eine Messeinrichtung zur Messung der Zusammensetzung und/oder der Eigenschaften des Blutes, eine Messeinrichtung zur Messung der Temperatur und/oder von durch Temperaturmessung bestimmbaren Werten und eine Messeinrichtung zur Messung hämodynamischer Parameter und/oder von durch Druckmessung bestimmbaren Werten ausgebildet ist.In the illustrated embodiment, there are a total of three measuring devices 3 in the device 1, advantageously a measuring device for measuring the composition and / or properties of the blood, a measuring device for measuring the temperature and / or values that can be determined by temperature measurement, and a measuring device for measuring hemodynamic parameters and / or of values that can be determined by pressure measurement.
Hierdurch ist es möglich, sämtliche, für einen Operateur während einer Operation wichtigen Größen und Werte mittels einer Einrichtung 1, die sich z. B. in einer Blutbahn befindet, zu bestimmen.This makes it possible to use a device 1 to measure all the values and values that are important for a surgeon during an operation. B. is in a bloodstream to determine.
Da die Einrichtung 1 gleichzeitig als Katheter ausgebildet ist, sind zwischen den Messeinrichtungen 3 und dem Ende 2 der Einrichtung 1 seitliche Öffnungen 4 sowie im Bereich des Endes 2 eine endseitige Öffnung 5 vorgesehen, die mit einem, wie in Fig. 2 dargestellt, Infusions- bzw. Absaugkanal 6 verbunden sind.Since the device 1 is simultaneously designed as a catheter, there are lateral openings 4 between the measuring devices 3 and the end 2 of the device 1 and in the area of the end 2, an end opening 5 is provided which is connected to an infusion or suction channel 6, as shown in FIG. 2.
Das andere Ende der Einrichtung 1 ist mit einer herkömmlichen nicht dargestellten Infusions- bzw. Absaugeinrichtung für den Infusions- bzw. Absaugkanal 6 sowie einer ebenfalls nicht dargestellten Steuer- und Anzeigeeinrichtung für die Messeinrichtungen 3 verbunden.The other end of the device 1 is connected to a conventional infusion or suction device, not shown, for the infusion or suction channel 6, and to a control and display device, also not shown, for the measuring devices 3.
Die Einrichtung 1 wird vor einem operativen Eingriff mit dem Ende 2 in eine nicht dargestellte Blutbahn eingeführt und am gewünschten Untersuchungsort plaziert. Über die Öffnungen 4 bzw. 5 können Stoffe, wie z. B. Medikamente, injiziert oder Proben abgesaugt werden, während gleichzeitig Messungen über die Messeinrichtung 3 vorgenommen werden können .Before an operative intervention, the device 1 is inserted with its end 2 into a bloodstream (not shown) and placed at the desired examination site. Via the openings 4 and 5, substances such as. B. drugs, injected or aspirated samples, while measurements can be made on the measuring device 3 at the same time.
Fig. 2 zeigt eine Variante der erfindungsgemäßen Einrichtung 1, bei der die Messeinrichtungen 3 fest in die Einrichtung 1 integriert sind. Die in Fig. 2 beispielhaft dargestellte Messeinrichtung 3 besteht aus einem Empfänger und einem Sender, die winklig zueinander angeordnet sind. Die von dem Sender ausgestrahlten Wellen werden von der Flüssigkeit bzw. eventuell vorhandenen Luftblasen reflektiert und vom Empfänger wieder empfangen. Dabei treten je nach dem reflektierten Medium, d. h. Flüssigkeit oder Luftblasen, Unterschiede in der Frequenz der gesendeten und empfangenen Wellen auf, so dass mittels dieser Technik, z. B. im Blut befindliche Partikel wie z. B. Knochensplitter detektiert werden können.FIG. 2 shows a variant of the device 1 according to the invention, in which the measuring devices 3 are permanently integrated in the device 1. The measuring device 3 shown by way of example in FIG. 2 consists of a receiver and a transmitter, which are arranged at an angle to one another. The waves emitted by the transmitter are reflected by the liquid or any air bubbles present and received again by the receiver. Depending on the reflected medium, i. H. Liquid or air bubbles, differences in the frequency of the transmitted and received waves, so that by means of this technique, e.g. B. particles in the blood such. B. bone fragments can be detected.
Fig. 3 zeigt eine Ausführungsform der Einrichtung 1, bei der sich die Messeinrichtungen 3 in einem in der Einrich- tung 1 angeordneten endseitigen geschlossenen Kanal 7 befinden. Da der Kanal 7 endseitig geschlossen ist, kommen die darin angeordneten und verschieblichen Messeinrichtungen 3 nicht in Kontakt mit der zu überwachenden und die Einrichtung 1 umströmenden Flüssigkeit. Nach der Operation werden die Messeinrichtungen 3 aus dem Kanal (7) der Einrichtung 1 gezogen und können in einer neuen Einrichtung 1 eingesetzt und somit wiederverwertet werden, ohne dass es einer aufwendigen Sterilisation bedarf. Auch hier ist der Infusions- bzw. Absaugkanal 6 in der anderen Hälfte der Einrichtung 1 angeordnet.3 shows an embodiment of the device 1 in which the measuring devices 3 are located in a device 1 arranged end closed channel 7 are located. Since the channel 7 is closed at the end, the measuring devices 3 arranged and displaceable therein do not come into contact with the liquid to be monitored and flowing around the device 1. After the operation, the measuring devices 3 are pulled out of the channel (7) of the device 1 and can be used in a new device 1 and thus reused without the need for expensive sterilization. Here too, the infusion or suction channel 6 is arranged in the other half of the device 1.
Je nach der Art der Operation und der somit zu überwachenden Werte können bei der Einrichtung 1 mit einem Kanal 7 wahlweise die verschiedenen erforderlichen Messeinrichtungen 3 eingeführt werden, so dass jede Einrichtung 1 optimal auf den speziellen Anwendungsfall abgestimmt werden kann.Depending on the type of operation and the values to be monitored, the various required measuring devices 3 can optionally be introduced in the device 1 with a channel 7, so that each device 1 can be optimally adapted to the specific application.
Bei der in Fig. 4 dargestellten Ausführungsform der Einrichtung 1 ist der Infusions- bzw. Absaugkanal 6 mittig angeordnet, wobei beidseits des Infusions- bzw. Absaugkanals 6 endseitig geschlossene Kanäle 7 vorgesehen sind. In diese Kanäle 7 sind Messeinrichtungen 3 eingeführt. Es bedarf keiner näheren Erläuterung, dass in jedem Kanal 7 mehrere Messeinrichtungen 3 vorgesehen sein können.In the embodiment of the device 1 shown in FIG. 4, the infusion or suction channel 6 is arranged in the center, with channels 7 closed on both ends being provided on both sides of the infusion or suction channel. Measuring devices 3 are introduced into these channels 7. No further explanation is required that several measuring devices 3 can be provided in each channel 7.
Zusätzlich kann beispielsweise in dem Kanal 7 eine Impulse erzeugende und aussendende Vorrichtung vorgesehen sein. Dies bietet sich beispielsweise bei Herzoperationen an, bei dem die Herztätigkeit stabilisiert werden soll .In addition, for example, a pulse generating and emitting device can be provided in the channel 7. This is useful, for example, in cardiac surgery in which cardiac activity is to be stabilized.
Bei der in den Fig. 1 bis 4 dargestellten Einrichtung 1 handelt es sich um einen Katheter. Es ist selbstverständ- lieh, dass die Einrichtung 1 auch als Nadel ausgebildet sein kann, wobei in diesem Falle das Ende 2 spitz ausgebildet ist. Bei einer solchen Ausführungsform eignet sich die Einrichtung 1 auch zum Durchstoßen von Gewebe.The device 1 shown in FIGS. 1 to 4 is a catheter. It goes without saying lent that the device 1 can also be designed as a needle, in which case the end 2 is pointed. In such an embodiment, the device 1 is also suitable for piercing tissue.
Nach dem Durchstoßen der Gewebeschichten können beispielsweise Medikamente dosiert zugegeben werden, während gleichzeitig die Medikamentenkonzentration in dem betreffenden Körperorgan ermittelt wird.After puncturing the tissue layers, for example, drugs can be added in doses, while the drug concentration in the relevant body organ is determined at the same time.
Sofern die Einrichtung 1 als Nadel ausgebildet ist, bedarf es keiner seitlichen Öffnungen 4. If the device 1 is designed as a needle, no lateral openings 4 are required.

Claims

Ansprüche Expectations
1. Einrichtung (1) zum Einführen in Körperhohlorgane, insbesondere in Blutbahnen, bestehend aus einem im wesentlichen länglich ausgebildeten Instrument mit zumindest einer in einem im Bereich des in das Körperhohlorgan, insbesondere die Blutbahn, eingeführten Endes (2) der Einrichtung (1) geschlossenen Kanal (7) befindlichen Messeinrichtung (3), dadurch gekennzeichnet, dass zur Messung der Zusammensetzung und/oder der Eigenschaften des Blutes eine geeignete Messeinrichtung (3) vorgesehen ist.1. Device (1) for insertion into hollow body organs, in particular in blood vessels, consisting of an essentially elongated instrument with at least one in an in the area of the inserted into the hollow body organ, in particular the bloodstream, end (2) of the device (1) closed Channel (7) located measuring device (3), characterized in that a suitable measuring device (3) is provided for measuring the composition and / or the properties of the blood.
2. Einrichtung (1) nach Anspruch 1, dadurch gekennzeichnet, dass die Messeinrichtung (3) als optische Messeinrichtung (3) ausgebildet ist und das Instrument zumindest im Bereich der Messeinrichtung (3) aus einem für die zur Messung optischer Strahlung durchlässigen und eine optische Messung ermöglichenden Material besteht.2. Device (1) according to claim 1, characterized in that the measuring device (3) is designed as an optical measuring device (3) and the instrument at least in the area of the measuring device (3) from one that is transparent to optical radiation and one optical Material enabling measurement.
3. Einrichtung (1) nach Anspruch 1 oder 2, dadurch gekennzeichnet, dass die Messeinrichtung (3) in einem Chip integriert ist.3. Device (1) according to claim 1 or 2, characterized in that the measuring device (3) is integrated in a chip.
4. Einrichtung (1) zum Einführen in Körperhohlorgane, insbesondere in Blutbahnen, bestehend aus einem im Wesentlichen länglich ausgebildeten Instrument mit zumindest einer in einem im Bereich des in das Körperhohlorgan, insbesondere die Blutbahn, eingeführten Endes (2) der Einrichtung (1) geschlossenen Kanal (7) befindlichen Messeinrichtung (3), insbesondere nach einem der Ansprüche 1 bis 3, dadurch gekennzeichnet, dass zur Messung der Temperatur des in der Blutbahn fließenden Blutes und/oder von durch Temperaturmessung (en) bestimmbaren Werten, insbesondere der Flussgeschwindigkeit, eine geeignete Messeinrichtung (3) vorgesehen ist.4. Device (1) for insertion into hollow body organs, in particular in blood vessels, consisting of an essentially elongated instrument with at least one in the area of the end (2) inserted into the hollow body organ, in particular the bloodstream Device (1) closed channel (7) located measuring device (3), in particular according to one of claims 1 to 3, characterized in that for measuring the temperature of the blood flowing in the bloodstream and / or values which can be determined by temperature measurement (s), A suitable measuring device (3) is provided, in particular the flow velocity.
5. Einrichtung (1) nach Anspruch 4, dadurch gekennzeichnet, dass die Messeinrichtung (3) als Temperaturmesseinrichtung und/oder als Wärmeflusssensor ausgebildet ist.5. Device (1) according to claim 4, characterized in that the measuring device (3) is designed as a temperature measuring device and / or as a heat flow sensor.
6. Einrichtung (1) nach Anspruch 4 oder 5, dadurch gekennzeichnet, dass die Messeinrichtung (3) in einem Chip integriert ist.6. Device (1) according to claim 4 or 5, characterized in that the measuring device (3) is integrated in a chip.
7. Einrichtung (1) zum Einführen in Körperhohlorgane, insbesondere in Blutbahnen, bestehend aus einem im Wesentlichen länglich ausgebildeten Instrument mit zumindest einer in einem im Bereich des in das Körperhohlorgan, insbesondere in die Blutbahn, eingeführten Endes (2) der Einrichtung (1) geschlossenen Kanal (7) befindlichen Messeinrichtung, insbesondere nach einem der Ansprüche 1 bis 6, dadurch gekennzeichnet, dass zur Messung hämodyna- mischer Parameter des Blutes und/oder von durch Druckmessung (en) bestimmbaren Werten eine geeignete Messeinrichtung (3) vorgesehen ist.7. Device (1) for insertion into hollow body organs, in particular in blood vessels, consisting of an essentially elongated instrument with at least one end (2) of the device (1) inserted in the region of the hollow body organ, in particular into the bloodstream. Closed channel (7) located measuring device, in particular according to one of claims 1 to 6, characterized in that a suitable measuring device (3) is provided for measuring hemodynamic parameters of the blood and / or values determinable by pressure measurement (s).
8. Einrichtung (1) nach Anspruch 7, dadurch gekennzeichnet, dass die Messeinrichtung (3) für die Messung von Druck, insbesondere reflektiertem Schalldruck eines Schallerzeugers, ausgebildet ist und das Instrument zumindest im Bereich der Messeinrichtung (3) einen eine Druckübertragung weitergebenden Bereich aufweist . 8. The device (1) according to claim 7, characterized in that the measuring device (3) is designed for the measurement of pressure, in particular reflected sound pressure of a sound generator, and the instrument has, at least in the area of the measuring device (3), a region which transmits pressure ,
9. Einrichtung (1) nach Anspruch 8, dadurch gekennzeichnet, dass die Druckmesseinrichtung als Druckaufnehmer, insbesondere Piezoelement , ausgebildet ist.9. Device (1) according to claim 8, characterized in that the pressure measuring device is designed as a pressure sensor, in particular a piezo element.
10. Einrichtung (1) nach Anspruch 9, dadurch gekennzeichnet, dass die Druckmesseinrichtung als Ultraschallsonde ausgebildet ist.10. Device (1) according to claim 9, characterized in that the pressure measuring device is designed as an ultrasonic probe.
11. Einrichtung (1) nach einem der Ansprüche 7 bis 10, dadurch gekennzeichnet, dass die Messeinrichtung (3) in einem Chip integriert ist.11. Device (1) according to one of claims 7 to 10, characterized in that the measuring device (3) is integrated in a chip.
12. Einrichtung (1) nach einem der Ansprüche 1 bis 11, dadurch gekennzeichnet, dass in dem Instrument zusätzlich eine Impulse, vorzugsweise Herzschrittmacherimpulse, erzeugende und aussendende Vorrichtung vorgesehen ist .12. Device (1) according to one of claims 1 to 11, characterized in that an additional pulse, preferably pacemaker pulses, generating and transmitting device is provided in the instrument.
13. Einrichtung (1) nach Anspruch 12, dadurch gekennzeichnet, dass die Vorrichtung in einem Chip integriert ist .13. Device (1) according to claim 12, characterized in that the device is integrated in a chip.
14. Einrichtung (1) nach einem der Ansprüche 1 bis 13, dadurch gekennzeichnet, dass zusätzlich zumindest ein Infusions- bzw. Absaugkanal (6) , dessen in der Blutbahn befindlicher Endbereich zumindest eine Öffnung (5) aufweist, vorgesehen ist.14. Device (1) according to one of claims 1 to 13, characterized in that in addition at least one infusion or suction channel (6), the end region of which is located in the bloodstream and has at least one opening (5), is provided.
15. Einrichtung (1) nach einem der Ansprüche 1 bis 14, dadurch gekennzeichnet, dass die Einrichtung (1) starr ausgebildet ist und an dem in das Körperhohlorgan einzuführenden Ende (2) eine Spitze aufweist.15. Device (1) according to one of claims 1 to 14, characterized in that the device (1) is rigid and has a tip at the end to be inserted into the hollow body organ (2).
16. Einrichtung (1) nach einem der Ansprüche 1 bis 15, dadurch gekennzeichnet, dass der endseitig geschlossen ausgebildete Kanal oder ein weiterer geschlossen ausgebildeter Kanal zur therapeutischen Temperaturbeeinflussung, z. B. mittels eines eingeführten Heiz- und/oder Kühlelementes oder Einbringen eines insbesondere zirkulierenden Temperiermediums, vorgesehen ist. 16. Device (1) according to one of claims 1 to 15, characterized in that the end is closed trained channel or another closed channel for therapeutic temperature control, z. B. by means of an introduced heating and / or cooling element or introduction of a circulating temperature control medium in particular, is provided.
PCT/EP2002/011242 2001-10-08 2002-10-08 Device for introducing into hollow organs of the body WO2003030706A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
EP02782853A EP1434519A2 (en) 2001-10-08 2002-10-08 Device for introducing into hollow organs of the body
JP2003533745A JP2005504599A (en) 2001-10-08 2002-10-08 Device introduced into the hollow organ of the body
AU2002346970A AU2002346970A1 (en) 2001-10-08 2002-10-08 Device for introducing into hollow organs of the body
US10/492,278 US20050020890A1 (en) 2001-10-08 2002-10-08 Device for introducing into hollow organs of the body

Applications Claiming Priority (2)

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DE20116460.4 2001-10-08
DE20116460U DE20116460U1 (en) 2001-10-08 2001-10-08 Device for insertion into hollow body organs

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WO2003030706A2 true WO2003030706A2 (en) 2003-04-17
WO2003030706A3 WO2003030706A3 (en) 2003-12-24

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EP (1) EP1434519A2 (en)
JP (1) JP2005504599A (en)
AU (1) AU2002346970A1 (en)
DE (1) DE20116460U1 (en)
WO (1) WO2003030706A2 (en)

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US20050020890A1 (en) 2005-01-27
DE20116460U1 (en) 2002-01-17
JP2005504599A (en) 2005-02-17
EP1434519A2 (en) 2004-07-07
AU2002346970A1 (en) 2003-04-22
WO2003030706A3 (en) 2003-12-24

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