UY28526A1 - Miméticos de glucocorticoides, métodos de preparación composiciones farmacéuticas y usos de los mismos - Google Patents

Miméticos de glucocorticoides, métodos de preparación composiciones farmacéuticas y usos de los mismos

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Publication number
UY28526A1
UY28526A1 UY28526A UY28526A UY28526A1 UY 28526 A1 UY28526 A1 UY 28526A1 UY 28526 A UY28526 A UY 28526A UY 28526 A UY28526 A UY 28526A UY 28526 A1 UY28526 A1 UY 28526A1
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UY
Uruguay
Prior art keywords
methods
pharmaceutical compositions
same
preparation pharmaceutical
compounds
Prior art date
Application number
UY28526A
Other languages
English (en)
Inventor
Pingrong Liu
Hidenori Takahashi
Younes Bekkali
Rajashekhar Betageri
Michel J Emmanuel
Abdelhakim Hammach
Original Assignee
Boehringer Ingelheim Pharma
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Publication date
Application filed by Boehringer Ingelheim Pharma filed Critical Boehringer Ingelheim Pharma
Publication of UY28526A1 publication Critical patent/UY28526A1/es

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    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
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    • A61K31/47—Quinolines; Isoquinolines
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Abstract

Compuestos de Fórmulas (IA), (IB), (IC), y (ID) en las cuales R1, R2, R3, R4, R5 y R6 son como se definen respectivamente en la presente para las Fórmulas (IA), (IB), (IC) y (ID), o un tautómero,profármaco, solvato o una sal de los mismos; composiciones frmacéuticas que contienen tales compuestos, y métodos para modular la función del receptor de glucocorticoides y métodos para tratar un estado o un cuadro patológico mediado por la función del receptor de glucocorticoides o caracterizado por procesos inflamatorios, alérgicos o proliferativos en un paciente que utiliza estos compuestos.
UY28526A 2003-09-24 2004-09-20 Miméticos de glucocorticoides, métodos de preparación composiciones farmacéuticas y usos de los mismos UY28526A1 (es)

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