SG11202007652UA - Camk2d antisense oligonucleotides and uses thereof - Google Patents

Camk2d antisense oligonucleotides and uses thereof

Info

Publication number
SG11202007652UA
SG11202007652UA SG11202007652UA SG11202007652UA SG11202007652UA SG 11202007652U A SG11202007652U A SG 11202007652UA SG 11202007652U A SG11202007652U A SG 11202007652UA SG 11202007652U A SG11202007652U A SG 11202007652UA SG 11202007652U A SG11202007652U A SG 11202007652UA
Authority
SG
Singapore
Prior art keywords
camk2d
antisense oligonucleotides
antisense
oligonucleotides
camk2d antisense
Prior art date
Application number
SG11202007652UA
Inventor
Richard E Olson
Brian R Anderson
Peter Hagedorn
Marianne Lerbech Jensen
Ivar M Mcdonald
Stephen E Mercer
Original Assignee
Bristol Myers Squibb Co
Roche Innovation Ct Copenhagen As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co, Roche Innovation Ct Copenhagen As filed Critical Bristol Myers Squibb Co
Publication of SG11202007652UA publication Critical patent/SG11202007652UA/en

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39541Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against normal tissues, cells
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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1137Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against enzymes
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    • A61K47/64Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
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    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
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    • C12N15/113Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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    • C12N2310/32Chemical structure of the sugar
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SG11202007652UA 2018-02-21 2019-02-21 Camk2d antisense oligonucleotides and uses thereof SG11202007652UA (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201862633502P 2018-02-21 2018-02-21
US201862635954P 2018-02-27 2018-02-27
US201862665998P 2018-05-02 2018-05-02
US201862778679P 2018-12-12 2018-12-12
PCT/US2019/018947 WO2019165067A1 (en) 2018-02-21 2019-02-21 Camk2d antisense oligonucleotides and uses thereof

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SG11202007652UA true SG11202007652UA (en) 2020-09-29

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US (2) US11083444B2 (en)
EP (1) EP3755800A1 (en)
JP (1) JP2021513861A (en)
KR (1) KR20200140805A (en)
CN (1) CN112020559A (en)
AU (1) AU2019226001A1 (en)
BR (1) BR112020016347A2 (en)
CA (1) CA3091789A1 (en)
IL (1) IL276549A (en)
MX (1) MX2020008581A (en)
SG (1) SG11202007652UA (en)
WO (1) WO2019165067A1 (en)

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Publication number Priority date Publication date Assignee Title
US8172855B2 (en) 2004-11-24 2012-05-08 Abdou M S Devices and methods for inter-vertebral orthopedic device placement
US8764806B2 (en) 2009-12-07 2014-07-01 Samy Abdou Devices and methods for minimally invasive spinal stabilization and instrumentation
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