NO20051100L - Pyrazolsammensetninger anvendelige som GSK-3-inhibitorer - Google Patents

Pyrazolsammensetninger anvendelige som GSK-3-inhibitorer

Info

Publication number
NO20051100L
NO20051100L NO20051100A NO20051100A NO20051100L NO 20051100 L NO20051100 L NO 20051100L NO 20051100 A NO20051100 A NO 20051100A NO 20051100 A NO20051100 A NO 20051100A NO 20051100 L NO20051100 L NO 20051100L
Authority
NO
Norway
Prior art keywords
inhibitors
gsk
compositions useful
compounds
protein kinase
Prior art date
Application number
NO20051100A
Other languages
English (en)
Inventor
Marion W Wannamaker
Cornelia J Forster
Larry C Park
Yung-Mae Yao
Original Assignee
Vertex Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vertex Pharma filed Critical Vertex Pharma
Publication of NO20051100L publication Critical patent/NO20051100L/no

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    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Abstract

Foreliggende oppfinnelse tilveiebringer en forbindelse med formel I: eller et farmasøytisk aJcseptabelt derivat derav. Disse for- bindelsene er proteinkinaseinhibitorer, spesielt OSK-3-pat- tedyxproteinkinaseinhibltorer. Oppfinnelsen tilveiebringer også farmasøytisk akseptable sanmensetninger omfattende forbindelsene ifølge oppfinnelsen og fremgangsmåter for an- vendelse av disse forbindelsene og sammensetningene ved be- handlingen av ulike proteinkinasemedierte forstyrrelser.
NO20051100A 2002-08-02 2005-03-01 Pyrazolsammensetninger anvendelige som GSK-3-inhibitorer NO20051100L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US40096702P 2002-08-02 2002-08-02
PCT/US2003/023950 WO2004013140A1 (en) 2002-08-02 2003-07-31 Pyrazole compositions useful as inhibitors of gsk-3

Publications (1)

Publication Number Publication Date
NO20051100L true NO20051100L (no) 2005-05-02

Family

ID=31495907

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20051100A NO20051100L (no) 2002-08-02 2005-03-01 Pyrazolsammensetninger anvendelige som GSK-3-inhibitorer

Country Status (26)

Country Link
US (2) US7491730B2 (no)
EP (1) EP1532145B1 (no)
JP (3) JP4733388B2 (no)
KR (1) KR20050032105A (no)
CN (2) CN101037438A (no)
AR (1) AR040773A1 (no)
AT (1) ATE339419T1 (no)
AU (2) AU2003257078B2 (no)
BR (1) BR0313176A (no)
CA (1) CA2494100C (no)
CO (1) CO5700772A2 (no)
DE (1) DE60308387T2 (no)
DK (1) DK1532145T3 (no)
EA (1) EA200500299A1 (no)
EC (1) ECSP055640A (no)
ES (1) ES2273043T3 (no)
HK (1) HK1081186A1 (no)
IL (1) IL166620A (no)
MX (1) MXPA05001367A (no)
NO (1) NO20051100L (no)
NZ (2) NZ538426A (no)
PL (1) PL374967A1 (no)
PT (1) PT1532145E (no)
TW (1) TWI324157B (no)
WO (1) WO2004013140A1 (no)
ZA (1) ZA200501124B (no)

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