KR20170010714A - Method, device and non-transitory computer-readable recording medium for measuring photoplethysmography signal - Google Patents
Method, device and non-transitory computer-readable recording medium for measuring photoplethysmography signal Download PDFInfo
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- KR20170010714A KR20170010714A KR1020160023632A KR20160023632A KR20170010714A KR 20170010714 A KR20170010714 A KR 20170010714A KR 1020160023632 A KR1020160023632 A KR 1020160023632A KR 20160023632 A KR20160023632 A KR 20160023632A KR 20170010714 A KR20170010714 A KR 20170010714A
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- light
- wavelength range
- illuminance
- pulse wave
- wave signal
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- 238000000034 method Methods 0.000 title claims abstract description 24
- 238000013186 photoplethysmography Methods 0.000 title description 5
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims description 23
- 229910052760 oxygen Inorganic materials 0.000 claims description 23
- 239000001301 oxygen Substances 0.000 claims description 23
- 239000008280 blood Substances 0.000 claims description 10
- 210000004369 blood Anatomy 0.000 claims description 10
- 238000012937 correction Methods 0.000 claims description 4
- 230000001678 irradiating effect Effects 0.000 claims description 3
- 238000004590 computer program Methods 0.000 claims description 2
- 230000005693 optoelectronics Effects 0.000 description 30
- 238000004891 communication Methods 0.000 description 18
- 230000006870 function Effects 0.000 description 12
- 238000004364 calculation method Methods 0.000 description 10
- 238000010586 diagram Methods 0.000 description 10
- 230000036772 blood pressure Effects 0.000 description 3
- 238000007796 conventional method Methods 0.000 description 3
- 238000005259 measurement Methods 0.000 description 3
- 102000001554 Hemoglobins Human genes 0.000 description 2
- 108010054147 Hemoglobins Proteins 0.000 description 2
- 206010020772 Hypertension Diseases 0.000 description 2
- 238000012545 processing Methods 0.000 description 2
- 235000019592 roughness Nutrition 0.000 description 2
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- 238000007792 addition Methods 0.000 description 1
- 230000036760 body temperature Effects 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 238000002059 diagnostic imaging Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000002599 functional magnetic resonance imaging Methods 0.000 description 1
- 239000008103 glucose Substances 0.000 description 1
- 230000004217 heart function Effects 0.000 description 1
- 230000001631 hypertensive effect Effects 0.000 description 1
- 230000031700 light absorption Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
- 230000029058 respiratory gaseous exchange Effects 0.000 description 1
- 239000004984 smart glass Substances 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 210000000106 sweat gland Anatomy 0.000 description 1
- 230000002123 temporal effect Effects 0.000 description 1
- 210000000707 wrist Anatomy 0.000 description 1
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
- A61B5/14551—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters for measuring blood gases
- A61B5/14552—Details of sensors specially adapted therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
- A61B5/0075—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by spectroscopy, i.e. measuring spectra, e.g. Raman spectroscopy, infrared absorption spectroscopy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
- A61B5/024—Detecting, measuring or recording pulse rate or heart rate
- A61B5/02416—Detecting, measuring or recording pulse rate or heart rate using photoplethysmograph signals, e.g. generated by infrared radiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
- A61B5/14551—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters for measuring blood gases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
- A61B5/7235—Details of waveform analysis
- A61B5/725—Details of waveform analysis using specific filters therefor, e.g. Kalman or adaptive filters
Abstract
Description
The present invention relates to a method, apparatus and non-transitory computer readable recording medium for measuring a photoelectrically-pulsating pulse signal.
Recently, the rapid development of science and technology has improved the quality of life of the whole human being, and many changes have occurred in the medical environment. In the past, medical images such as X-ray, CT, and fMRI were taken in the hospital, and it was possible to read the images only after several hours or several days.
However, after 10 years of medical imaging, a Picture Archive Communication System (PACS) has been introduced, which allows images to be transmitted to a monitor screen of a radiologist and then read out immediately. In addition, many ubiquitous healthcare-related medical devices that can confirm their blood sugar and blood pressure at any time without going to a hospital are widely used, and blood glucose patients or hypertensive patients use them in their own homes or offices. In particular, in the case of hypertension, which is the main cause of the invention of various diseases and the prevalence is increasing, a system for continuously measuring blood pressure and informing it in real time is needed, and various types of studies related thereto have been tried.
On the other hand, biometric information such as electrocardiogram, heart rate, body temperature information, oxygen saturation, electromyogram, sweat gland activity, foot volume, respiration rate as well as blood pressure is not limited to the biomedical information obtained from two or more contact points (necessarily physically attached) A technique capable of properly processing and measuring a bio-signal obtained from various points of the human body is required in order to obtain bio-information.
In particular, PhotoPlethysmoGraphy (PPG) signals are used to measure various biological information related to cardiac function, including oxygen saturation in blood (SpO2). According to the conventional optoelectronic pulse wave signal measuring technique, there is a technical restriction that a shielding structure is indispensably required in order to prevent an error caused by an external light source.
Hereinafter, the case of calculating the oxygen saturation in the blood using the optoelectronic pulse wave signal will be described in more detail as an example.
BACKGROUND ART As a conventional technique for measuring oxygen saturation (SpO2) in blood using a photoelectric pulse wave signal, visible light rays (for example, red light, green light, etc.) reflected from a human body and infrared light are detected, A technique of calculating oxygen saturation based on a photoelectric pulse wave signal according to each of visible light and infrared light has been introduced. In this conventional technique, the light absorption rate by oxygen hemoglobin (HbO2) in blood is higher than that of visible light It is based on the principle that it appears higher in light.
1 is an exemplary diagram illustrating an environment in which oxygen saturation is measured according to the prior art. 1, in the conventional
In order to accurately measure the optoelectronic pulse wave signal (and furthermore, the degree of oxygen saturation), the brightness (i.e., illuminance) of the light sensed by the
Thus, the present inventors propose a technique that can accurately measure the photoelectric pulse wave signal (and furthermore, oxygen saturation) in an environment in which the brightness of ambient light is not constant due to an external light source.
It is an object of the present invention to solve all the problems described above.
Further, the present invention is characterized in that the light of the first wavelength range and the light of the second wavelength range are irradiated to the user's body through the first filter section and the second filter section, respectively, and through each of the first filter section and the second filter section The light of the first wavelength range and the light of the second wavelength range which are incident through the first filter portion and the second filter portion, respectively, And a second photoelectric pulse wave signal corresponding to the light of the second wavelength range detected above and the first photoelectric pulse wave signal corresponding to the light of the first wavelength range detected above, And if the difference between at least one of the first illuminance and the second illuminance measured above and the predetermined reference illuminance is equal to or greater than a predetermined level, at least one of the first illuminance and the second illuminance, Relative relationship between reference illuminance A method and an apparatus capable of accurately measuring the optoelectronic pulse wave signal in an environment in which the brightness of the ambient light is not constant due to the external light source by correcting at least one of the first optoelectronic pulse wave signal and the second optoelectronic pulse wave signal, And a non-temporal computer-readable recording medium.
In order to accomplish the above object, a representative structure of the present invention is as follows.
According to one aspect of the present invention, there is provided a method for measuring a PPG signal, comprising the steps of: irradiating light in a first wavelength range and light in a second wavelength range through a first filter section and a second filter section, Wherein the first filter unit and the second filter unit respectively detect light in a first wavelength range and light in a second wavelength range that are incident through the first filter unit and the second filter unit, Measuring a first illuminance and a second illuminance, respectively, the illuminance of each of the light of the first wavelength range and the light of the second wavelength range incident through each of the first wavelength range and the second wavelength range, Generating a second optoelectronic pulse wave signal in accordance with the detected pulse wave signal and the light in the second wavelength range to be sensed; and calculating a difference between at least one of the measured first illuminance and the second illuminance and a predetermined reference illuminance, Set level , At least one of the first photoelectric pulse wave signal and the second photoelectric pulse wave signal is corrected with reference to a relative relationship between at least one of the measured first illuminance and the second illuminance and the predetermined reference illuminance The method comprising the steps of:
According to another aspect of the present invention, there is provided an apparatus for measuring a PPG signal, the apparatus comprising: a light source for emitting light in a first wavelength range and light in a second wavelength range through a first filter unit and a second filter unit, A first light receiving portion for detecting light in a first wavelength range and light in a second wavelength range incident through the first filter portion and the second filter portion, respectively, And a second illuminance measuring unit for measuring a first illuminance and a second illuminance, respectively, which are the illuminance of the light in the first wavelength range and the light in the second wavelength range incident through the second light receiving unit, the first filter unit and the second filter unit, A first illuminance sensor and a second illuminance sensor for generating a first photoelectric pulse wave signal corresponding to the light in the first wavelength range to be sensed and a second photoelectric pulse wave signal corresponding to the light in the second wavelength range to be sensed, Of the first and second illuminance measured, With reference to a relative relationship between at least one of the first illuminance and the second illuminance being measured and the predetermined reference illuminance, when the difference between the at least one and the preset reference illuminance is equal to or greater than a predetermined level, And a calculation unit for correcting at least one of the pulse wave signal and the second photoelectric pulse wave signal.
In addition, there is provided another non-transitory computer readable recording medium for recording a computer program for carrying out the method and apparatus for implementing the invention.
According to the present invention, it is possible to accurately measure the optoelectronic pulse wave signal even in an environment where the brightness of the ambient light is not constant due to the external light source.
According to the present invention, it is possible to enhance the accuracy of various biometric information that can be derived from the optoelectronic pulse wave signal.
In addition, according to the present invention, it is possible to prevent a spatial restriction from occurring due to the conventional shielding structure by employing a configuration that adaptively corrects a signal according to the sensed light based on the illuminance to be measured. Further, It is possible to easily mount the optoelectronic pulse wave signal measuring device even in a wearable device having a small size and shape limitation.
1 is a diagram illustrating an exemplary environment in which a photoelectric pulse wave signal is measured according to a conventional technique.
2 is a diagram schematically showing a configuration of an overall system according to an embodiment of the present invention.
3 is a diagram illustrating an internal configuration of an optoelectronic pulse wave signal measuring apparatus according to an embodiment of the present invention.
FIG. 4 is a diagram illustrating an exemplary view of an optoelectronic pulse wave signal measuring apparatus according to an embodiment of the present invention.
5 is a diagram illustrating a process of measuring a photoelectrically-converting pulse wave signal and oxygen saturation according to an embodiment of the present invention.
The following detailed description of the invention refers to the accompanying drawings, which illustrate, by way of illustration, specific embodiments in which the invention may be practiced. These embodiments are described in sufficient detail to enable those skilled in the art to practice the invention. It should be understood that the various embodiments of the present invention are different, but need not be mutually exclusive. For example, certain features, structures, and characteristics described herein may be implemented in other embodiments without departing from the spirit and scope of the invention in connection with an embodiment. It is also to be understood that the position or arrangement of the individual components within each disclosed embodiment may be varied without departing from the spirit and scope of the invention. The following detailed description is, therefore, not to be taken in a limiting sense, and the scope of the present invention is to be limited only by the appended claims, along with the full scope of equivalents to which such claims are entitled, if properly explained. In the drawings, like reference numerals refer to the same or similar functions throughout the several views.
Hereinafter, preferred embodiments of the present invention will be described in detail with reference to the accompanying drawings, so that those skilled in the art can easily carry out the present invention.
Configuration of the entire system
The overall system for measuring the optoelectronic pulse wave signal according to an embodiment of the present invention will be described in detail as follows.
2 is a diagram schematically showing a configuration of an overall system according to an embodiment of the present invention.
2, the overall system according to an exemplary embodiment of the present invention may include a
The
Next, an optoelectronic pulse wave
The function of the optoelectronic pulse wave
Finally, the
Also, according to an embodiment of the present invention, the
Configuration of photoelectric pulse wave signal measurement device
Hereinafter, the internal configuration of the optoelectronic pulse wave
3 is a diagram illustrating an internal configuration of an optoelectronic pulse wave signal measuring apparatus according to an embodiment of the present invention.
3, an optoelectronic pulse wave
FIG. 4 is a diagram illustrating an exemplary view of an optoelectronic pulse wave signal measuring apparatus according to an embodiment of the present invention.
First, according to an embodiment of the present invention, the
According to an embodiment of the present invention, the light in the first wavelength range and the light in the second wavelength range, which are emitted from the
Next, according to an embodiment of the present invention, the
According to an embodiment of the present invention, light in the first wavelength range and light in the second wavelength range, which are sensed by the
Next, in accordance with an embodiment of the present invention, the
Next, in accordance with an embodiment of the present invention, the
According to an embodiment of the present invention, when the difference between at least one of the measured first illuminance and second illuminance and the predetermined reference illuminance is equal to or greater than a predetermined level, And at least one of the first photoelectric pulse wave signal and the second photoelectric pulse wave signal may be corrected with reference to a relative relationship between at least one of the first illuminance and the second illuminance and the predetermined reference illuminance.
Specifically, the
Therefore, according to the present invention, it is possible to accurately measure the optoelectronic pulse wave signal in an environment in which the brightness of the ambient light is not constant due to the external light source, without employing the conventional shielding structure causing spatial limitation .
According to the embodiment of the present invention, the calculating
Specifically, the calculating
For example, the oxygen saturation computation model according to an embodiment of the present invention may include a first photoelectric pulse wave signal (i.e., a signal based on red light) and a second photoelectric pulse wave signal (i.e., And a signal based on the oxygen concentration of the hemoglobin in the blood). However, it should be noted that the oxygen saturation calculation model according to the present invention is not necessarily limited to those listed above, but may be modified within the scope of achieving the object of the present invention.
5 is a diagram illustrating a process of measuring oxygen saturation according to an embodiment of the present invention.
5, the first
5, the first
5, the
5, the
Next, the
The
The embodiments of the present invention described above can be implemented in the form of program instructions that can be executed through various computer components and recorded in a non-transitory computer readable recording medium. The non-transitory computer readable medium may include program instructions, data files, data structures, etc., either alone or in combination. The program instructions recorded on the non-transitory computer-readable recording medium may be those specially designed and constructed for the present invention or may be those known to those skilled in the computer software arts. Examples of non-transitory computer-readable media include magnetic media such as hard disks, floppy disks and magnetic tape, optical recording media such as CD-ROMs, DVDs, magneto-optical media such as floppy disks magneto-optical media), and hardware devices specifically configured to store and execute program instructions such as ROM, RAM, flash memory, and the like. Examples of program instructions include machine language code such as those generated by a compiler, as well as high-level language code that can be executed by a computer using an interpreter or the like. The hardware device may be configured to operate as one or more software modules for performing the processing according to the present invention, and vice versa.
While the present invention has been particularly shown and described with reference to exemplary embodiments thereof, it is to be understood that the invention is not limited to the disclosed exemplary embodiments, but, on the contrary, Those skilled in the art will appreciate that various modifications, additions and substitutions are possible, without departing from the scope and spirit of the invention as disclosed in the accompanying claims.
Therefore, the spirit of the present invention should not be construed as being limited to the above-described embodiments, and all of the equivalents or equivalents of the claims, as well as the following claims, I will say.
100: Network
200: Photoelectric pulse wave signal measuring device
210:
220:
230: illuminance sensor unit
240:
250:
260:
270:
300: device
Claims (11)
Irradiating light of the first wavelength range and light of the second wavelength range to the user's body through the first filter section and the second filter section respectively,
Wherein the first filter unit and the second filter unit respectively detect the light in the first wavelength range and the light in the second wavelength range, Measuring a first illuminance and a second illuminance, which are illuminances of light in the first wavelength range and light in the second wavelength range, respectively,
Generating a first photoelectric pulse wave signal according to the detected light of the first wavelength range and a second photoelectric pulse wave signal corresponding to the light of the second wavelength range to be sensed,
And if the difference between at least one of the measured first illuminance and the second illuminance and the predetermined reference illuminance is equal to or greater than a predetermined level, a relative relationship between at least one of the measured first illuminance and the second illuminance, Correcting at least one of the first photoelectric pulse wave signal and the second photoelectric pulse wave signal with reference to the relationship
≪ / RTI >
In the correction step,
If the difference between at least one of the measured first illuminance and the second illuminance and the predetermined reference illuminance is equal to or greater than a predetermined level and the difference between at least one of the measured first illuminance and the second illuminance and the predetermined reference illuminance And scaling at least one of the first photoelectric pulse wave signal and the second photoelectric pulse wave signal based on a relative ratio.
Calculating the oxygen saturation in the blood of the human body of the user with reference to the corrected first photoelectric pulse wave signal and the second photoelectric pulse wave signal,
≪ / RTI >
Wherein the first filter portion and the second filter portion selectively transmit light in the first wavelength range and light in the second wavelength range, respectively.
Wherein the first wavelength range includes a wavelength range of 490 nm to 780 nm and the second wavelength range includes a wavelength range of 800 nm to 980 nm.
A first light emitting portion and a second light emitting portion for irradiating the light of the first wavelength range and the light of the second wavelength range to the user's body through the first filter portion and the second filter portion,
A first light receiving unit and a second light receiving unit that respectively detect light in a first wavelength range and light in a second wavelength range that are incident through the first filter unit and the second filter unit,
A first illuminance sensor for measuring a first illuminance and a second illuminance, respectively, which are illuminances of light in a first wavelength range and light in a second wavelength range incident through the first filter portion and the second filter portion, respectively; 2 illuminance sensor, and
Generates a first photoelectric pulse wave signal corresponding to the detected light in the first wavelength range and a second photoelectric pulse wave signal corresponding to the light in the second wavelength range to be sensed, With reference to a relative relationship between at least one of the first illuminance and the second illuminance being measured and the predetermined reference illuminance, when the difference between the at least one and the preset reference illuminance is equal to or greater than a predetermined level, And a second photoelectric pulse wave signal for correcting at least one of the pulse wave signal and the second photo-
/ RTI >
Wherein the calculating unit calculates the difference between at least one of the measured first illuminance and the second illuminance and the predetermined illuminance when the difference between at least one of the measured first illuminance and the second illuminance and the preset reference illuminance is equal to or greater than a predetermined level, And scaling at least one of the first photoelectric pulse wave signal and the second photoelectric pulse wave signal based on a relative ratio between the reference light intensity and the reference illuminance.
Wherein the calculating section calculates the oxygen saturation degree in the blood of the human body of the user with reference to the corrected first photoelectric pulse wave signal and the second photoelectric pulse wave signal.
Wherein the first filter portion and the second filter portion selectively transmit light in the first wavelength range and light in the second wavelength range, respectively.
Wherein the first wavelength range includes a wavelength range of 490 nm to 780 nm and the second wavelength range includes a wavelength range of 800 nm to 980 nm.
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
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US15/215,127 US20170020420A1 (en) | 2015-07-20 | 2016-07-20 | Method, apparatus and non-transitory computer-readable recording medium for measuring photoplethysmography signals |
PCT/KR2016/007893 WO2017014550A1 (en) | 2015-07-20 | 2016-07-20 | Method and apparatus for measuring photoplethysmography signal, and non-transitory computer-readable recording medium |
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KR1020150102695 | 2015-07-20 | ||
KR20150102695 | 2015-07-20 |
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KR1020160023632A KR20170010714A (en) | 2015-07-20 | 2016-02-26 | Method, device and non-transitory computer-readable recording medium for measuring photoplethysmography signal |
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