KR20170010713A - Method, device and non-transitory computer-readable recording medium for measuring photoplethysmography signal - Google Patents
Method, device and non-transitory computer-readable recording medium for measuring photoplethysmography signal Download PDFInfo
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- KR20170010713A KR20170010713A KR1020160023600A KR20160023600A KR20170010713A KR 20170010713 A KR20170010713 A KR 20170010713A KR 1020160023600 A KR1020160023600 A KR 1020160023600A KR 20160023600 A KR20160023600 A KR 20160023600A KR 20170010713 A KR20170010713 A KR 20170010713A
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- wavelength range
- illuminance
- pulse wave
- wave signal
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- 238000000034 method Methods 0.000 title claims abstract description 27
- 238000013186 photoplethysmography Methods 0.000 title description 5
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims description 24
- 229910052760 oxygen Inorganic materials 0.000 claims description 24
- 239000001301 oxygen Substances 0.000 claims description 24
- 239000008280 blood Substances 0.000 claims description 11
- 210000004369 blood Anatomy 0.000 claims description 11
- 238000004364 calculation method Methods 0.000 claims description 9
- 230000001678 irradiating effect Effects 0.000 claims description 4
- 238000004590 computer program Methods 0.000 claims description 2
- 230000005693 optoelectronics Effects 0.000 description 26
- 238000004891 communication Methods 0.000 description 18
- 230000006870 function Effects 0.000 description 14
- 238000010586 diagram Methods 0.000 description 9
- 238000005259 measurement Methods 0.000 description 4
- 230000036772 blood pressure Effects 0.000 description 3
- 238000007796 conventional method Methods 0.000 description 3
- 102000001554 Hemoglobins Human genes 0.000 description 2
- 108010054147 Hemoglobins Proteins 0.000 description 2
- 206010020772 Hypertension Diseases 0.000 description 2
- 238000012545 processing Methods 0.000 description 2
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- 238000007792 addition Methods 0.000 description 1
- 230000036760 body temperature Effects 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 238000002059 diagnostic imaging Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000002599 functional magnetic resonance imaging Methods 0.000 description 1
- 239000008103 glucose Substances 0.000 description 1
- 230000004217 heart function Effects 0.000 description 1
- 230000001631 hypertensive effect Effects 0.000 description 1
- 238000005286 illumination Methods 0.000 description 1
- 230000031700 light absorption Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
- 230000000541 pulsatile effect Effects 0.000 description 1
- 230000036387 respiratory rate Effects 0.000 description 1
- 239000004984 smart glass Substances 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 210000000106 sweat gland Anatomy 0.000 description 1
- 210000000707 wrist Anatomy 0.000 description 1
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
- A61B5/14551—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters for measuring blood gases
- A61B5/14552—Details of sensors specially adapted therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
- A61B5/024—Detecting, measuring or recording pulse rate or heart rate
- A61B5/02416—Detecting, measuring or recording pulse rate or heart rate using photoplethysmograph signals, e.g. generated by infrared radiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
- A61B5/14551—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters for measuring blood gases
Abstract
Description
The present invention relates to a method, apparatus and non-transitory computer readable recording medium for measuring a photoelectrically-pulsating pulse signal.
Recently, the rapid development of science and technology has improved the quality of life of the whole human being, and many changes have occurred in the medical environment. In the past, medical images such as X-ray, CT, and fMRI were taken in the hospital, and it was possible to read the images only after several hours or several days.
However, after 10 years of medical imaging, a Picture Archive Communication System (PACS) has been introduced, which allows images to be transmitted to a monitor screen of a radiologist and then read out immediately. In addition, many ubiquitous healthcare-related medical devices that can confirm their blood sugar and blood pressure at any time without going to a hospital are widely used, and blood glucose patients or hypertensive patients use them in their own homes or offices. In particular, in the case of hypertension, which is the main cause of the invention of various diseases and the prevalence is increasing, a system for continuously measuring blood pressure and informing it in real time is needed, and various types of studies related thereto have been tried.
On the other hand, biometric information such as electrocardiogram, heart rate, body temperature information, oxygen saturation in blood, electromyogram, sweat gland activity, foot volume, respiratory rate, etc., as well as blood pressure, are obtained from two or more contact points (not necessarily physically attached) It is required to provide a technique capable of appropriately processing and measuring a living body signal obtained from various points of the human body in order to obtain the living body information.
In particular, PhotoPlethysmoGraphy (PPG) signals are used to measure various biological information related to cardiac function, including oxygen saturation (SpO 2 ) in the blood. According to the conventional optoelectronic pulse wave signal measuring technique, there is a technical restriction that a shielding structure is indispensably required in order to prevent an error caused by an external light source.
Hereinafter, the case of calculating the oxygen saturation in the blood using the optoelectronic pulse wave signal will be described in more detail as an example.
BACKGROUND ART [0002] A conventional technique for measuring oxygen saturation (SpO 2 ) in blood using a photoelectric pulse wave signal is a technique for detecting visible light (for example, red light, green light, etc.) and infrared light reflected from a human body, A technique of calculating the oxygen saturation based on the optoelectronic pulse wave signal according to each of visible light and infrared light has been introduced. In this conventional technique, the light absorption rate by oxygen hemoglobin (HbO 2 ) And that it appears higher in the infrared light than in the infrared light.
1 is an exemplary diagram illustrating an environment in which oxygen saturation is measured according to the prior art. 1, in the conventional
In order to accurately measure the optoelectronic pulse wave signal (and furthermore, the degree of oxygen saturation), the brightness (i.e., illuminance) of the light sensed by the
Thus, the present inventors propose a technique that can accurately measure the photoelectric pulse wave signal (and furthermore, oxygen saturation) in an environment in which the brightness of ambient light is not constant due to an external light source.
It is an object of the present invention to solve all the problems described above.
Further, the present invention is characterized in that the light of the first wavelength range and the light of the second wavelength range are irradiated to the user's body through the first filter section and the second filter section, respectively, and through each of the first filter section and the second filter section The light of the first wavelength range and the light of the second wavelength range which are incident through the first filter portion and the second filter portion, respectively, And a second photoelectric pulse wave signal corresponding to the light of the second wavelength range detected above and the first photoelectric pulse wave signal corresponding to the light of the first wavelength range detected above, The light of the first wavelength range irradiated to the user's body and the light of the second wavelength range irradiated to the user's body are measured so that the difference between at least one of the first illuminance and the second illuminance measured above and the predetermined reference illuminance is less than a predetermined level, At least one of the light in the wavelength range It is another object of the present invention to provide a method, apparatus, and non-transitory computer readable recording medium capable of accurately measuring a photoelectric pulse wave signal in an environment in which the brightness of ambient light is not constant due to an external light source.
In order to accomplish the above object, a representative structure of the present invention is as follows.
According to one aspect of the present invention, there is provided a method for measuring a PPG signal, comprising the steps of: irradiating light in a first wavelength range and light in a second wavelength range through a first filter section and a second filter section, Wherein the first filter unit and the second filter unit respectively detect light in a first wavelength range and light in a second wavelength range that are incident through the first filter unit and the second filter unit, Measuring a first illuminance and a second illuminance, respectively, the illuminance of each of the light of the first wavelength range and the light of the second wavelength range incident through each of the first wavelength ranges and the first illuminance and the second illuminance, And generating a second optoelectronic pulse wave signal corresponding to the detected light in the second wavelength range, wherein in the step of irradiating, at least one of the measured first illuminance and the second illuminance, Set baseline It is less than a predetermined level difference between, a method for adjusting at least one of the brightness of the first light and the second wavelength range of the wavelength range of light to be irradiated with respect to the body of the user is provided.
According to another aspect of the present invention, there is provided an apparatus for measuring a PPG signal, the apparatus comprising: a light source for emitting light in a first wavelength range and light in a second wavelength range through a first filter unit and a second filter unit, A first light receiving portion for detecting light in a first wavelength range and light in a second wavelength range incident through the first filter portion and the second filter portion, respectively, And a second illuminance measuring unit for measuring a first illuminance and a second illuminance, respectively, which are the illuminance of the light in the first wavelength range and the light in the second wavelength range incident through the second light receiving unit, the first filter unit and the second filter unit, A first illuminance sensor, a second illuminance sensor, a first photoelectric pulse wave signal according to the light of the first wavelength range to be sensed, and a second photoelectric pulse wave signal corresponding to the light of the second wavelength range to be sensed, And a second illuminance measurement step A controller for adjusting the brightness of at least one of the light in the first wavelength range and the light in the second wavelength range irradiated to the human body of the user so that a difference between at least one of the degrees and the preset reference illuminance is less than a predetermined level, Is provided.
In addition, there is provided another non-transitory computer readable recording medium for recording a computer program for carrying out the method and apparatus for implementing the invention.
According to the present invention, it is possible to accurately measure the optoelectronic pulse wave signal even in an environment where the brightness of the ambient light is not constant due to the external light source.
According to the present invention, it is possible to enhance the accuracy of various biometric information that can be derived from the optoelectronic pulse wave signal.
Further, according to the present invention, by adopting a configuration in which the brightness of light irradiated to the human body is adaptively adjusted, spatial restriction can be prevented from occurring due to the conventional shielding structure, and furthermore, It is possible to easily mount the optoelectronic pulse wave signal measuring device even in a wearable device having a restriction.
1 is a diagram illustrating an exemplary environment in which a photoelectric pulse wave signal is measured according to a conventional technique.
2 is a diagram schematically showing a configuration of an overall system according to an embodiment of the present invention.
3 is a diagram illustrating an internal configuration of an optoelectronic pulse wave signal measuring apparatus according to an embodiment of the present invention.
FIG. 4 is an exemplary illustration of an apparatus for measuring a pulsatile pulse wave signal according to an embodiment of the present invention. FIG.
5 is a diagram illustrating a process of measuring a photoelectrically-converting pulse wave signal and oxygen saturation according to an embodiment of the present invention.
The following detailed description of the invention refers to the accompanying drawings, which illustrate, by way of illustration, specific embodiments in which the invention may be practiced. These embodiments are described in sufficient detail to enable those skilled in the art to practice the invention. It should be understood that the various embodiments of the present invention are different, but need not be mutually exclusive. For example, certain features, structures, and characteristics described herein may be implemented in other embodiments without departing from the spirit and scope of the invention in connection with an embodiment. It is also to be understood that the position or arrangement of the individual components within each disclosed embodiment may be varied without departing from the spirit and scope of the invention. The following detailed description is, therefore, not to be taken in a limiting sense, and the scope of the present invention is to be limited only by the appended claims, along with the full scope of equivalents to which such claims are entitled, if properly explained. In the drawings, like reference numerals refer to the same or similar functions throughout the several views.
Hereinafter, preferred embodiments of the present invention will be described in detail with reference to the accompanying drawings, so that those skilled in the art can easily carry out the present invention.
Configuration of the entire system
The overall system for measuring the optoelectronic pulse wave signal according to an embodiment of the present invention will be described in detail as follows.
2 is a diagram schematically showing a configuration of an overall system according to an embodiment of the present invention.
2, the overall system according to an exemplary embodiment of the present invention may include a
The
Next, an optoelectronic pulse wave
The function of the optoelectronic pulse wave
Finally, the
Also, according to an embodiment of the present invention, the
Configuration of photoelectric pulse wave signal measurement device
Hereinafter, the internal configuration of the optoelectronic pulse wave
3 is a diagram illustrating an internal configuration of an optoelectronic pulse wave signal measuring apparatus according to an embodiment of the present invention.
3, an optoelectronic pulse wave
FIG. 4 is a diagram illustrating an example of a photoelectric pulse wave signal measuring apparatus according to an embodiment of the present invention.
First, according to an embodiment of the present invention, the
According to an embodiment of the present invention, the light in the first wavelength range and the light in the second wavelength range, which are emitted from the
As described later, according to an embodiment of the present invention, the brightness of the light in the first wavelength range or the light in the second wavelength range irradiated to the user's body is determined by the brightness of the first The illuminance or the second illuminance may be adjusted in such a direction as to match the predetermined reference illuminance. That is, according to an embodiment of the present invention, the light of the first wavelength range irradiated to the human body of the user is adjusted so that the difference between at least one of the first illuminance and the second illuminance and the preset reference illuminance is less than a predetermined level And the brightness of at least one of the light in the second wavelength range can be adaptively adjusted.
For example, when the first illuminance measured by the first
Next, according to an embodiment of the present invention, the
According to an embodiment of the present invention, light in the first wavelength range and light in the second wavelength range, which are sensed by the
Next, in accordance with an embodiment of the present invention, the
Next, in accordance with an embodiment of the present invention, the
More specifically, the calculating
In addition, the
Therefore, according to the present invention, it is possible to accurately measure the optoelectronic pulse wave signal in an environment in which the brightness of the ambient light is not constant due to the external light source, without employing the conventional shielding structure causing spatial limitation .
Meanwhile, according to an embodiment of the present invention, the calculating
Specifically, the calculating
For example, the oxygen saturation computation model according to an embodiment of the present invention may include a first photoelectric pulse wave signal (i.e., a signal based on red light) and a second photoelectric pulse wave signal (i.e., And a signal based on the oxygen concentration of the hemoglobin in the blood). However, it should be noted that the oxygen saturation calculation model according to the present invention is not necessarily limited to those listed above, but may be modified within the scope of achieving the object of the present invention.
5 is a diagram illustrating a process of measuring a photoelectrically-converting pulse wave signal and oxygen saturation according to an embodiment of the present invention.
5, the first
5, the first
5, the
5, a
Next, the
The
The embodiments of the present invention described above can be implemented in the form of program instructions that can be executed through various computer components and recorded in a non-transitory computer readable recording medium. The non-transitory computer readable medium may include program instructions, data files, data structures, etc., either alone or in combination. The program instructions recorded on the non-transitory computer-readable recording medium may be those specially designed and constructed for the present invention or may be those known to those skilled in the computer software arts. Examples of non-transitory computer-readable media include magnetic media such as hard disks, floppy disks and magnetic tape, optical recording media such as CD-ROMs, DVDs, magneto-optical media such as floppy disks magneto-optical media), and hardware devices specifically configured to store and execute program instructions such as ROM, RAM, flash memory, and the like. Examples of program instructions include machine language code such as those generated by a compiler, as well as high-level language code that can be executed by a computer using an interpreter or the like. The hardware device may be configured to operate as one or more software modules for performing the processing according to the present invention, and vice versa.
While the present invention has been particularly shown and described with reference to exemplary embodiments thereof, it is to be understood that the invention is not limited to the disclosed exemplary embodiments, but, on the contrary, Those skilled in the art will appreciate that various modifications, additions and substitutions are possible, without departing from the scope and spirit of the invention as disclosed in the accompanying claims.
Therefore, the spirit of the present invention should not be construed as being limited to the above-described embodiments, and all of the equivalents or equivalents of the claims, as well as the following claims, I will say.
100: Network
200: Photoelectric pulse wave signal measuring device
210:
220:
230: illuminance sensor unit
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250:
260:
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300: device
Claims (13)
Irradiating light of the first wavelength range and light of the second wavelength range to the user's body through the first filter section and the second filter section respectively,
Wherein the first filter unit and the second filter unit respectively detect the light in the first wavelength range and the light in the second wavelength range, Measuring a first illuminance and a second illuminance, respectively, the illuminance of each of the light in the first wavelength range and the light in the second wavelength range, and
Generating a first photoelectric pulse wave signal according to the light of the first wavelength range to be sensed and a second photoelectric pulse wave signal corresponding to the light of the second wavelength range to be sensed
Lt; / RTI >
In the irradiation step,
The light of the first wavelength range and the light of the second wavelength range irradiated to the human body of the user so that the difference between at least one of the measured first illuminance and the second illuminance and the predetermined reference illuminance is less than a predetermined level, / RTI > wherein the brightness of at least one of the plurality of pixels is adjusted.
In the irradiation step,
At least one of the light in the first wavelength range and the light in the second wavelength range irradiated to the human body of the user is measured in a case where at least one of the measured first illuminance and second illuminance is less than the preset reference illuminance How to increase.
In the generating step,
Wherein at least one of the measured first illuminance and the second illuminance exceeds a predetermined reference illuminance, a reference ratio between at least one of the first illuminance and the second illuminance to be measured and the predetermined reference illuminance is referred to Thereby correcting at least one intensity of the first photoelectric pulse wave signal and the second photoelectric pulse wave signal.
Calculating oxygen saturation in blood of the user's body with reference to the first photoelectric pulse wave signal and the second photoelectric pulse wave signal,
≪ / RTI >
Wherein the first filter portion and the second filter portion selectively transmit light in the first wavelength range and light in the second wavelength range, respectively.
Wherein the first wavelength range includes a wavelength range of 490 nm to 780 nm and the second wavelength range includes a wavelength range of 800 nm to 980 nm.
A first light emitting portion and a second light emitting portion for irradiating the light of the first wavelength range and the light of the second wavelength range to the user's body through the first filter portion and the second filter portion,
A first light receiving unit and a second light receiving unit that respectively detect light in a first wavelength range and light in a second wavelength range that are incident through the first filter unit and the second filter unit,
A first illuminance sensor for measuring a first illuminance and a second illuminance, respectively, which are illuminances of light in a first wavelength range and light in a second wavelength range which are incident through the first filter portion and the second filter portion, respectively; 2 illuminance sensor,
A calculation unit for generating a first photoelectric pulse wave signal corresponding to the light of the first wavelength range to be sensed and a second photoelectric pulse wave signal corresponding to the light of the second wavelength range to be sensed,
The light of the first wavelength range and the light of the second wavelength range irradiated to the human body of the user so that the difference between at least one of the measured first illuminance and the second illuminance and the predetermined reference illuminance is less than a predetermined level, And a control unit
/ RTI >
Wherein the controller is configured to control the light of the first wavelength range and the light of the second wavelength range that are irradiated to the user's body in the case where at least one of the measured first illuminance and the second illuminance is less than the preset reference illuminance A device that increases one brightness.
The calculating unit may calculate a relative illuminance between at least one of the measured first illuminance and the second illuminance and the predetermined reference illuminance when at least one of the measured first illuminance and the second illuminance exceeds the predetermined reference illuminance And corrects the intensity of at least one of the first photoelectric pulse wave signal and the second photoelectric pulse wave signal with reference to the ratio.
Wherein the calculating unit calculates an oxygen saturation degree in the blood of the human body of the user with reference to the first photoelectric pulse wave signal and the second photoelectric pulse wave signal.
Wherein the first filter portion and the second filter portion selectively transmit light in the first wavelength range and light in the second wavelength range, respectively.
Wherein the first wavelength range includes a wavelength range of 490 nm to 780 nm and the second wavelength range includes a wavelength range of 800 nm to 980 nm.
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
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US15/215,178 US20170020421A1 (en) | 2015-07-20 | 2016-07-20 | Method, apparatus and non-transitory computer-readable recording medium for measuring photoplethysmography signals |
PCT/KR2016/007893 WO2017014550A1 (en) | 2015-07-20 | 2016-07-20 | Method and apparatus for measuring photoplethysmography signal, and non-transitory computer-readable recording medium |
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KR20150102694 | 2015-07-20 | ||
KR1020150102694 | 2015-07-20 |
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Cited By (1)
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WO2021177797A1 (en) * | 2020-03-05 | 2021-09-10 | 서울대학교병원 | Method, system, and non-transitory computer-readable recording medium for providing information about post-cardiac arrest prognosis |
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WO2021177797A1 (en) * | 2020-03-05 | 2021-09-10 | 서울대학교병원 | Method, system, and non-transitory computer-readable recording medium for providing information about post-cardiac arrest prognosis |
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