KR20040098400A - Healthcare hand,skinwashing compositions - Google Patents

Abstract

PURPOSE: Provided is a hand cleansing composition which has excellent skin stability, storage stability, antibacterial activity and cleansing and rinsing properties. Therefore, the composition is useful for cleansing hands of persons working for medical services. CONSTITUTION: A hand cleansing composition comprises 50 wt.% of lower alcohol as a sterilizing agent, 15-35 parts by weight of water as a diluent, 0.05-5 parts by weight of carbomer as a thickening agent, 0.1-2 parts by weight of tocopherol acetate(vitamin E) as a skin condition controlling agent, 0.1-10 parts by weight of glycerine and 0.2-4 parts by weight of propylene glycol as a moisturizing agent, 0.3-1 parts by weight of isopropyl myristate as an emollient, an appropriate amount of aminomethyl propanol as a pH controlling agent. The composition further contains 62 parts by weight of methanol and a small amount of fragrance, and has a viscosity of 4000-12000 centipoise, and a pH value of 7-8.5.

Description

Composition for hand skin cleaning {HEALTHCARE HAND, SKINWASHING COMPOSITIONS}

The present invention relates to a health care skin cleanser composition containing a lower alcohol as a main solution for cleaning, and more particularly, used in the hand cleaning of health care workers mainly with excellent skin stability, preservation stability, antimicrobial activity, detergency, and rinsability. It relates to a skin care composition for health care.

One example of the known technology for the conventional hand cleaner is the volatilizing cleaner disclosed in Korean Patent Laid-Open No. 2000-64060. This includes 60-73% ethyl alcohol, 0.1-0.24% acrylic acid, 4.0-5.0% triethanolamine, 0.01-0.02% carbomer, 1-3 %% para-chloro- meta-xylenol (PCMX). And 2.5-3.5% by volume of Aloe Vera homogeneously mixed to dilute 10-15% by volume of purified water to prepare a gel or lotion type. The complex toxic component of ethyl alcohol and PCMX not only has excellent sterilizing effect, but also because of the volatilization of alcohol, it does not need to be naturally dried in a few seconds after washing, so it does not need to be wiped with towels or paper towels. It is a detergent.

Another known technique is the antimicrobial alcohol gel disclosed in US Pat. No. 4,956,170. It is a high alcohol content antimicrobial gel composition, based on the total weight, ethanol 60-75%, thickener 0.4-2%, diisopropanol neutralizer 15-100%, hydrocarbon emollient 0.5-2.5% and other fatty acid esters, fatty alcohols And a gel-like composition having a viscosity of about 10,000-100,000 CPs as a composition comprising polyhydric alcohol and the like and containing at least 20% water as the remainder. Such a composition has an antimicrobial effect, which is useful for use as a hand cleaner in a hospital, etc. Also, the composition is easily dried due to the volatility of the alcohol contained therein, whereas the skin lubricating ingredient remains on the skin to prevent roughening.

In addition, hand sanitizers are often used for disinfection, sterilization, and skin protection as personal hygiene, and have recently been developed for the protection of hand skin for medical, beauty, hygiene, caregivers, cooks, and housewives.

The present invention relates to a skin sterilizing cleansing composition for health care free of hand dirt, which is most suitable for sterilizing and cleaning of skin, especially hands.

Intra-hospital infection in hospitals has been an important task comparable to the treatment of patients' diseases.

Intra-hospital infections in hospitals have been reported to infect other patients through the hands of doctors and nurses, and must be completely disinfected before the treatment of one patient before the treatment of another patient.

In this case, ethanol solutions of cationic fungicides such as benzalkonium chloride and chlorohexazine gluconate are widely used as disinfectants. However, it is generally practiced to wash hands with fatty acid soap to remove hand dirt before using the disinfectant to improve the effectiveness of the disinfectant. This fatty acid soap has strong degreasing power, which is easy to cause hand dirt, and because it is anionic, if it is not sufficiently washed with water, it reacts with a cationic fungicide, which is a disinfectant, and significantly reduces its effect. Many medical sites do not know the reaction of cations and anions, and many of them do not wash well with water, which not only impairs the effectiveness of the disinfectant but also causes hand dirt from fatty soaps. . Dirty hands have a vicious cycle because they have a lot of bacteria and are prone to secondary infections.

Against this background, for medical workers who have to disinfect their hands several times daily to prevent infection in the hospital, they can be used safely without worrying about hand dirt and have sufficient sterilization effect. There is a need for a disinfectant cleaner that is free of ionic reactions with cationic fast-drying disinfectants.

The present invention has been made to solve the above problems, and its purpose is to have sufficient disinfecting power and at the same time have proper degreasing power and proper detergency without sticking, without causing hand dirt even in high frequency of use. To provide a cleaning composition for sterilization without fear of reaction with a cationic fast-drying type disinfectant which is widely used. Sterilizing and cleaning composition used here is not limited to hand sterilization cleaning, it can be widely used in medical sites, elderly homes, and general homes, such as skin disinfection during surgery and beddings such as medical equipment and bedroom sheets. It is to provide a sanitary cleaning composition, in particular a hand sanitary cleaner.

The present invention contains more than 50% by weight of lower alcohol, as a thickener, carbomer, skin condition control agent, tocopheryl acetate (vitamin E) as a moisturizing agent, glycerin, propylene glycol, isopropanmyristate as emollient, pH adjuster Provided is a hand skin cleansing composition for health care containing water as an iminomethylpropanol and diluent and containing other small amounts of fragrance.

As the lower alcohol to be blended in the composition of the present invention, methanol, ethanol, propanol, isopropanol, butanol, isobutanol can be used, and ethanol or isopropanol is particularly preferable.

The skin cleaning composition according to the present invention is mainly used as a skin cleansing composition for hand washing, and can be used by all chefs, doctors, nurses, caregivers, housewives, patients, and the general public.

The composition of the present invention is 50-80% by weight of ethyl alcohol, 0.05 to 5% by weight carbomer, 0.1-2% by weight tocopherol acetate (vitamin E), 0.1-10% by weight glycerin, 0.2-4% by weight propylene glycol %, Isopropyl myristate 0.3-1% by weight, iminomethylpropanol amount, 15-35% by weight of water, fragrance amount is a composition for hand skin cleansing.

The cleaning composition according to the present invention comprises 50-80% by weight of ethyl alcohol, preferably 60-70% by weight, carbomer 0.05-5% by weight, skin conditioning agent, tocopherol acetate (vitamin) as a moisturizing agent. E) 0.1-2% by weight, 0.1-10% by weight glycerin as moisturizer, 0.2-4% by weight propylene glycol as moisturizer, preferably 0.2-2% by weight, isopropyl myristate 0.3-1% by emollient %, iminomethylpropanol as a pH adjuster, 15-40% by weight of water as a diluent, and a preservative, a pigment and a flavoring skin cleanser.

Ethyl alcohol is the most common fungicide and can be used in the range of 60-95% by volume and is an antimicrobial active ingredient approved by the FDA.

The detergent of the present invention exhibits antibacterial activity against various bacteria, antifungal activity against yeast and fungi, and has good skin conditioning and skin moisturizing effect.

The present invention will be described in more detail with reference to the following preferred embodiments of the present invention, but the present invention is not limited thereto.

Example 1.

0.05-5 parts by weight of carbomer was added to 15-35 parts by weight of water, while stirring, 0.1-2 parts by weight of tocopherol acetate (vitamin E), 0.1-10 parts by weight of glycerine, 0.2-4 parts by weight of propylene glycol, isopropyl Add 0.3-1 part by weight of myristate, an appropriate amount of iminomethylpropanol, 62 parts by weight of methanol, and an appropriate amount of perfume.

The condenser is placed in a container and the mixture is stirred for 2 minutes at a paddle mixer 30rpm and a homomixer 3600rpm while slowly adding the above raw materials.

A cleaning composition is obtained, which is transparent and has a viscosity of 4,000 to 12,000 centipoise (gel) and a pH of 7-8.5.

Example 2.

The antimicrobial efficacy of the composition obtained in the above examples is tested in vitro.

Exposure sterilization was performed for 15 seconds against microorganisms, yeast and fungi such as Salmonella, Vibrio, Escherichia coli, Enterococci, E. coli, Pneumococcal, Pseudomonas aeruginosa, and black mold. Inoculating materials such as microorganisms and bacterial spore viruses were added to the test composition, and then a portion of the sample was lifted and placed in a neutralizing medium for l5 seconds, and then microbial survival rate was measured by standard plate counting technique.

The percentage reduction of test microorganisms after 15 seconds exposure was greater than 99.99%, indicating a high reduction in gram-positive, gram-negative bacteria, yeast and fungi.

In addition, 50 individual panelists, including hospital workers, nursing workers, patients, and housewives, were randomly selected for personal sensory examination of sanitary cleansing composition. After 15 seconds, l5 minutes after applying this cleaning product to their hands and skin. After checking the condition of dryness, texture, and stickiness, the result is fast drying, good feeling and no stickiness (45 persons). After 3 days a day, it is applied to the hands and skin for 15 days. A good result (41 people) was obtained with a good smell, no rust and stickiness, and a smooth texture.

The present invention has sufficient disinfecting power and moderate degreasing power and proper detergency without stickiness and stickiness, and does not cause hand dirt even when the frequency of use is high. To provide a sterile cleaning composition.

The cleaning agent according to the present invention provides a very good antibacterial activity and antifungal activity, has a moderate detergency, no stickiness and stickiness, and a hand skin cleanser with a soft feeling after use.

Claims (2)

It contains more than 50% by weight of lower alcohol, carbomer as a thickener, skin conditioner, tocopheryl acetate (vitamin E) as a moisturizer, glycerin, propylene glycol, emollient Rossi isopropyl myristate, iminomethyl as a pH regulator Hand skin cleansing composition containing water as propanol and diluent and other small amount of fragrance 0.1-2 parts by weight of tocopherol acetate (vitamin E), 0.1-10 parts by weight of glycerol, 0.2-4 parts by weight of propylene glycol, isopropyl, while adding 0.05-5 parts by weight of carbomer to 15-35 parts of water Skin wash with a viscosity of 4,000 to 12,000 centipoise (gel) and a pH of 7-8.5 prepared by mixing and stirring while gradually adding 0.3-1 part by weight of Myristate, an appropriate amount of iminomethylpropanol, 62 parts by weight of methanol, and an appropriate amount of perfume. Manufacturing method of molten composition