KR102313585B1 - Injection module and inject medicine device comprising the same - Google Patents

Abstract

Disclosed is a drug injection device. A drug injection device according to an embodiment includes a detection member including a hollow formed along the longitudinal direction, the void communicating with the hollow is formed on the surface; and a biosensor connected to the detection member and configured to sense a concentration of a target biological material.

Description

Needle head and drug injection device including the same

The following embodiment relates to a needle head for user convenience and a drug injection device including the same.

Conventional insulin-dependent patients had to measure blood glucose at each time point, such as fasting, after lunch, before dinner, after dinner, and before going to bed, with a self-measured blood glucose device. In the insulin-dependent patient, when blood glucose control is necessary from the above-described blood glucose measurement results, an insulin syringe is used to determine and inject an appropriate amount of insulin, thereby managing blood glucose.

For the above-described blood sugar management, a self blood sugar measuring device, an insulin cartridge, an insulin injection device, and the like are required. In addition, insulin-dependent patients had to accurately record the measured blood sugar level and the amount of insulin injected, and show the record to a specialist to receive feedback.

For example, an insulin-dependent patient can check the current blood sugar level through a self-monitoring device by dropping blood collected by piercing the skin through a lancet to check their current blood sugar level on a test strip. Thereafter, when it is confirmed through the self-monitoring device that blood glucose control is necessary, the insulin-dependent patient can prepare an insulin injector. Insulin-dependent patients should manually set the dose on their insulin injector as recommended by their doctor. In addition, insulin-dependent patients have to place an insulin injector on the skin to be injected and then manually inject it. Furthermore, insulin-dependent patients should directly record the measured blood glucose level and insulin injection amount on a blood glucose control record sheet.

The drug injection device according to an embodiment may measure blood glucose and perform insulin injection in a single invasive process.

The drug injection device according to an embodiment can minimize the discomfort felt by the user in the invasive process for use.

A drug injection device according to an embodiment includes a needle head for insertion into an invasive site in the skin, wherein the needle head includes a first needle member having a longitudinal direction; and a second needle member having a longitudinal direction parallel to the first needle member and slidable in the longitudinal direction.

In one side, the first needle member may include a hollow formed along the longitudinal direction, and the second needle member may be disposed in the hollow.

In one side, the end of the first needle member may include a cutting edge (cutting edge) shape.

In one side, the second needle member may include a through hole penetrating the inside along the longitudinal direction.

In one side, the second needle member may be formed of a porous material that allows the target biological material to pass through the through hole from the outer surface in one direction.

In one side, the reaction layer is applied to the second needle member, comprising an enzyme that reacts with the target biological material; and a biosensor including a sensing electrode for generating an electrical signal according to the reaction of the enzyme.

In one side, at least a portion of the outer surface of the second needle member may be in contact with the outer surface of the first needle member.

The drug injection device according to an embodiment includes a hollow formed along the longitudinal direction and has a first needle member for invasion into the invasive site in the skin, and a longitudinal direction parallel to the first needle member along the longitudinal direction A needle head comprising a second needle member sliding operation; an analysis unit connected to the needle head and analyzing the user's biometric information; and a drug supply unit connected to the needle head and supplying a drug into the user's body.

In one side, based on a cross section perpendicular to the longitudinal direction, the second needle member may be located in the hollow of the first needle member.

In one side, the drug of the drug supply unit may be injected into the invasive site through the hollow of the first needle member.

In one side, the second needle member may include a suction port formed therein along the longitudinal direction to suck the user body fluid sample in the invasive site.

In one aspect, the needle head may further include a biosensor for sensing biomaterial information from the body fluid in the invasive site.

In one side, the needle head may further include a support for supporting the first and second needle members, and the biosensor may be disposed on the support.

In one side, further comprising a control unit for controlling the operation of the needle head, the control unit through the sliding operation of the second needle member, it is possible to adjust the pressure in the hollow of the first needle member.

In one side, the control unit moves the second needle member toward the support part in the process of sucking the user's body fluid sample through the hollow, and in the process of injecting the drug into the user's body through the hollow, the second The needle member may be moved in the direction of the invasion site.

The drug injection device according to an embodiment may minimize the user's inconvenience by performing blood glucose level measurement and insulin injection through a single invasion.

The drug injection device according to an embodiment may remove a gap between the biomaterial measurement time point and the drug injection time point.

Effects of the drug injection device according to an embodiment are not limited to those mentioned above, and other effects not mentioned will be clearly understood by those skilled in the art from the description below.

The following drawings attached to this specification illustrate a preferred embodiment of the present invention, and serve to further understand the technical spirit of the present invention together with the detailed description of the present invention, so the present invention is limited to the matters described in those drawings It should not be construed as being limited.
1 is a use state diagram of a drug injection device according to an embodiment.
2 is a perspective view of a drug injection device according to an embodiment.
3 is a block diagram of a drug injection device according to an embodiment.
4 is a block diagram of a drug injection device according to an embodiment.
5A is a partial perspective view of a drug injection device according to an embodiment.
5B is a partial perspective view of a drug injection device according to an embodiment.
Figure 5c is a partial cross-sectional view of the drug injection device of Figure 5b.
6 is a cross-sectional view taken along line VI-VI of FIG. 5 .
FIG. 7 is a cross-sectional view taken along line VI-VI of FIG. 5 .
8 is a partial perspective view of a drug injection device according to an embodiment.
9 is a cross-sectional view taken along line IX-IX of FIG. 8 .
FIG. 10 is a cross-sectional view taken along line IX-IX of FIG. 8 .
11 is an operation diagram of a drug injection device according to an embodiment.
12 is an operation diagram of a drug injection device according to an embodiment.
13 is a partial perspective view of a drug injection device according to an embodiment.

Hereinafter, embodiments will be described in detail with reference to exemplary drawings. In adding reference numerals to the components of each drawing, it should be noted that the same components are given the same reference numerals as much as possible even though they are indicated on different drawings. In addition, in the description of the embodiment, if it is determined that a detailed description of a related known configuration or function interferes with the understanding of the embodiment, the detailed description thereof will be omitted.

In addition, in describing the components of the embodiment, terms such as first, second, A, B, (a), (b), etc. may be used. These terms are only for distinguishing the components from other components, and the essence, order, or order of the components are not limited by the terms. When it is described that a component is “connected”, “coupled” or “connected” to another component, the component may be directly connected or connected to the other component, but another component is between each component. It will be understood that may also be "connected", "coupled" or "connected".

Components included in one embodiment and components having a common function will be described using the same names in other embodiments. Unless otherwise stated, a description described in one embodiment may be applied to another embodiment, and a detailed description in the overlapping range will be omitted.

1 is a use state diagram of a drug injection device according to an embodiment.

Referring to FIG. 1 , a drug injection device 1 according to an embodiment may be used to sense information of a biological material in a body of a user U and inject a drug into the body U of the user. The drug injection device 1 may be used in such a way that it is invaded into the user U's body. The drug injection device 1 may penetrate the skin of the user U and be inserted into the body. Hereinafter, the body part of the user U to which the drug injection device 1 is invaded is expressed as an 'invasive site (A)'.

The drug injection device 1 may sense biomaterial information in the body of the user (U). The drug injection device 1 may be in contact with the user U's body fluid to sense information on the target biological material in the body fluid, for example, the concentration of the biological material in the body fluid. For example, the drug injection device 1 may sense a blood glucose rate in a body fluid. The drug injection device 1 may inject a drug into the body of the user U through the invasive site. The drug injected by the drug injection device 1 may include a material associated with a target biological material. For example, when the target biomaterial information is a blood glucose level, the drug injected into the body of the user U through the drug injection device 1 may be insulin for reducing the blood glucose level. However, this is an example, and the target biomaterial sensed by the drug injection device 1 and the type of the injected drug are not limited thereto.

Figure 2 is a perspective view of a drug injection device according to an embodiment, Figure 3 is a configuration diagram of the drug injection device according to an embodiment.

2 and 3 , the drug injection device according to an embodiment may include a needle head 10 and a body 11 .

The needle head 10 may be inserted into the user's body invasive site. The needle head 10 may contact the body fluid of the invasive site for information sensing of the target biological material, or may inject a drug into the user's body through the invasive site. The needle head 10 may be connected to the body 11 .

The main body 11 may include a housing 111, a display 112, a manipulation unit 113, a drug supply unit 114, a driving unit 115, an analysis unit 117, a control unit 116, and a communication unit (not shown). can

The housing 111 may form the exterior of the main body 11 . The housing 111 accommodates the components of the drug supply device therein, and may support each component so that the accommodated components are positioned in place. The housing 111 may be gripped by a user. The housing 111 may have a shape that is easy for a user to grip, for example, a pen shape as shown in FIG. 2 . However, since the above-described shape of the housing 111 is only an example, the shape of the housing 111 is not limited thereto.

The display 112 may be disposed on the outer surface of the housing 111 . The display 112 may display the information related to the drug supply device to the outside, so that the user can recognize the related information. For example, the display 112 may display the user's biometric information analyzed through the drug supplying device or information related to the operation of the drug supplying device. The display 112 may display the displayed information in various types of visual representations such as text, symbols, and graphs. In addition to the visual display displayed through the display 112 , an auxiliary display, for example, an auditory display through a speaker, or a tactile display through vibration may be simultaneously implemented in the drug injection device 1 .

The manipulation unit 113 is disposed on the outer surface of the housing 111 and may be operated by a user. The manipulation unit 113 may receive input information by a user's control action, and transmit the received manipulation information to the control unit 116 to be described later. The drug injection device 1 may be operated by the operation information transmitted to the control unit 116 .

The drug supply unit 114 may accommodate the drug therein. The drug supply unit 114 may receive the drug in various ways. For example, a drug cartridge in which a drug is stored may be inserted into the drug supply unit 114 . In this case, the drug cartridge may be replaced in the drug supply unit 114 when the stored drug is exhausted. On the other hand, the drug supply unit 114 may include a receiving chamber for accommodating the drug supplied from the outside. The drug supply unit 114 may be connected to the needle head (10). In this case, a drug delivery path connecting the drug supply unit 114 and the needle head 10 may be formed in the body 11 . Accordingly, the drug of the drug supply unit 114 may move to the needle head 10 according to the operation of the drug injection device 1 to be injected into the invasive site.

The driving unit 115 may control the discharge of the drug contained in the drug supply unit 114 . In other words, the driving unit 115 may apply an external force of the drug storage unit so that the drug is discharged from the drug supply unit 114 to the needle head 10 . Depending on whether the driving unit 115 operates, the discharge of the drug discharged from the drug storage unit may be controlled.

The analysis unit 117 may analyze the user's biometric information. The analysis unit 117 is electrically connected to the needle head 10 , and may analyze information of the biological material obtained through the needle head 10 . The analyzer 117 may analyze the user's biometric information based on the target biomaterial information sensed by the biosensor 104, which will be described later. For example, the analysis unit 117 may obtain a digital value corresponding to the amount of the target biomaterial by analog-to-digital converting (ADC) the electrical signal generated by the biosensor 104 . have. At the same time, the analysis unit 117 may acquire target data related to user biometric information by correcting and analyzing the obtained digital value. For example, the analysis unit 117 may obtain information about the user's blood glucose level through the biosensor 104 , and may obtain evaluation data on the user's health condition based on the information.

The analysis unit 117 may determine a supply amount of a drug to be injected to the user, based on the analyzed biometric information. For example, the analyzer 117 may determine an insulin injection amount suitable for the user based on the measured blood glucose level. The analysis unit 117 determines the insulin supply amount through an algorithm for insulin compared to the analyzed blood glucose level, or insulin suitable for the user based on data input from an external server, for example, the doctor's evaluation data based on the user's medical record. The dosage can be determined. Since the insulin dose may vary individually depending on the user's weight, medication, and health condition, the analysis unit 117 may determine the dose of the drug customized for each individual through storage information of the user's body data. However, the method of determining the amount of drug supply through the analysis unit 117 is not limited to the above-described example, and may be determined in various ways.

The control unit 116 may control the operation of the drug supply device. The controller 116 may control the operation of the driving unit 115 according to, for example, a drug supply amount determined through the analysis unit 117 . Therefore, the amount of the drug discharged from the drug supply unit 114 to the needle head 10, that is, the amount of the drug injected into the user's body can be controlled.

The communication unit (not shown) may establish communication with an external server and a mobile terminal. For example, the communication unit may establish wireless communication with the mobile terminal, and may establish communication with an external server (eg, a cloud server) via the mobile terminal. The communication unit may transmit biometric information to an external server via the mobile terminal and receive injection information from the external server.

4 is a block diagram of a drug injection device according to an embodiment.

Referring to FIG. 4 , the drug injection device 1 according to an embodiment may include a detachable needle head 10 and a body 11 .

The needle head 10 and the body 11 may be physically connected. For example, a first fastening part (not shown) may be formed on the main body 11 , and a second fastening part (not shown) capable of being fastened with the first fastening part may be formed on the needle head 10 . The first fastening part and the second fastening part may be connected to each other by a fastening structure, for example, a screw method. On the other hand, the first fastening part and the second fastening part are fastened to each other through magnetic coupling, thereby physically connecting the needle head 10 and the main body 11 .

The needle head 10 and the body 11 may be electrically connected at the same time as the physical connection. The body 11 and the needle head 10 may include a first connector 1181 and a second connector 1182 that are electrically connected, respectively. The first connector 1181 and the second connector 1182 are electrically connected in a state in which the main body 11 and the needle head 10 are fastened to each other, thereby transferring information of the needle head 10 to the main body 11 . Alternatively, the signal of the body 11 may be transmitted to the needle head 10 . For example, information on the target biological material sensed by the needle head 10 may be transmitted to the main body 11 or the needle head 10 may be operated according to an operation signal of the main body 11 . In addition, power may be supplied from the body 11 to the needle head 10 .

The needle head 10 needs to be periodically replaced according to contamination or damage due to the nature of the needle head 10 in contact with the user's body fluid. When the needle head 10 can be fastened to the main body 11, the user can replace the used needle head 10 by separating it from the main body 11, so that the maintainability of the drug injection device 1 is improved. can

The needle head 10 may include a support 103 , a detection member 101 , and a biosensor 104 .

The support part 103 may support the detection member 101 . The support 103 may be directly connected to the body 11 . The support part 103 may be provided with a second fastening part that can be fastened to the first fastening part provided on the main body 11 , and a second connector 1182 electrically connected to the first connector 1181 may be disposed. .

The detection member 101 may be used to extract a user's bodily fluid sample. The detection member 101 may be directly inserted into the user's skin invasive site. In other words, the detection member 101 may penetrate the user's skin and invade the body. The detection member 101 may have a longitudinal direction protruding from the support part 103 in one direction. The end of the detection member 101 may be formed in a form capable of penetrating the skin and invasive. For example, the end of the detection member 101 may have a shape that forms an oblique line with respect to the longitudinal direction with respect to the longitudinal direction.

The biosensor 104 may sense information on the target biological material, for example, the concentration of the target biological material, from the bodily fluid sample extracted through the detection member 101 . When the target biomaterial is glucose in the body fluid, the biosensor 104 may sense the user's blood glucose level. The biosensor 104 may be disposed on the support 104 . However, unlike this, the biosensor 104 may be directly attached to the detection member 101 .

The biosensor 104 may generate an electrical signal by reacting with a target biomaterial in a body fluid. For example, the biosensor 104 may be a transducer that reacts with a target biomaterial to generate an electrical signal corresponding to the concentration of the biomaterial in the user's body. However, this is only an example, and various known methods may be applied to the method by which the biosensor 104 senses information on the target biomaterial.

Hereinafter, the needle head 10 portion of the drug injection device 1 according to an embodiment will be described in detail. In describing the drug injection device 1, the contents overlapping with those described above will be omitted.

Figure 5a is a partial perspective view of the drug injection device according to an embodiment, Figure 5b is a partial perspective view of the drug injection device according to an embodiment, Figure 5c is a partial cross-sectional view of the drug injection device of Figure 5b, Figure 6 is 5A is a cross-sectional view taken along line VI-VI, and FIG. 7 is another cross-sectional view taken along line VI-VI of FIG. 5A.

5A to 6 , the drug injection device according to an embodiment may be inserted into the invasive site of the user's body through the needle head 10 . The needle head 10 may include a detection member 101 and a support 103 supporting the detection member 101 .

The detection member 101 may have a longitudinal direction protruding from the support part 103 in one direction. The detection member 101 may include a hollow 1011 penetrating the inside along the longitudinal direction. The hollow 1011 may extract a bodily fluid sample from the invasive site into which the detection member 101 is inserted. For example, the detection member 101 may suck the bodily fluid sample from the bodily fluid of the invasive site through a capillary action. On the other hand, as a negative pressure is applied to the hollow 1011 of the detection member 101, the body fluid sample in the invasive site may be sucked.

The detection member 101 may have a void 1012 communicating with the hollow 1011 formed therein may be formed on the surface. The detection member 101 may be formed of a porous material such that a plurality of pores 1012 are formed. For example, the detection member 101 may include fluorinated ethylene propylene (FEP).

The detection member 101 may permeate the body fluid of the invasive site into the hollow 1011 through the plurality of pores 1012 . In this case, the detection member 101 may transmit the target biological material in the body fluid in one direction from the outside toward the hollow 1011 . In other words, the body fluid outside the detection member 101 may flow into the hollow 1011 through the void 1012 , while the material inside the hollow 1011 may pass through the void 1012 to the outside of the detection member 101 . discharge can be prevented. For example, in the process of extracting and sensing the user's bodily fluid, the detection member 101 prevents the compound generated through a chemical reaction in the sensing process from being discharged to the outside through the void 1012, so that the compound enters the user's body. reverse injection can be prevented.

Meanwhile, in FIG. 5A , the hollow 1011 of the detection member 101 communicates with the end, but unlike the hollow 1011 , the hollow 1011 does not communicate up to the end of the detection member 101, as shown in FIGS. 5B and 5C . As described above, it may be formed only inside the detection member 101 .

As shown in FIGS. 5B and 5C , when the hollow 1011 does not penetrate to the end of the detection member, that is, when the site to be inserted into the user's body is sealed, the user's body fluid is only passed through the hollow 1012 through the hollow 1011 can be introduced into the When the size of the pore 1012 is limited to a specific range, only a component that can pass through the void 1012 among the components of the user's body fluid may be introduced into the hollow 1011 . In addition, since the material inside the hollow 1011 can also be discharged to the outside of the hollow 1011 only through the pores 1012 , it is possible to effectively prevent the reverse discharge of a material having an increased molecular size according to a chemical reaction.

Referring to FIG. 7 , the biosensor 104 may be disposed inside the detection member 101 ′. For example, the biosensor 104 may be attached to the inner wall of the detection member 101 forming the hollow 1011 . The biosensor 104 may react with the target biological material in the bodily fluid introduced into the hollow 1011 to sense information on the target biological material, for example, the concentration of the target biological material. When the target biomaterial is glucose, the biosensor 104 may sense the user's blood glucose information. The biosensor 104 may include a reaction layer 1042 and a sensing electrode 1041 .

The reaction layer 1042 may be applied to the inner surface of the detection member 101 ′. The reaction layer 1042 may include an enzyme that reacts with a target biological material. For example, the enzyme of the reaction layer 1042 may chemically react with glucose in the body fluid component.

The sensing electrode 1041 may generate an electrical signal by a chemical reaction of an enzyme. The electrical signal generated by the sensing electrode 1041 may be a signal for a blood glucose level in the body. The signal generated by the sensing electrode 1041 may be transmitted to the analysis unit in the main body. The sensing electrodes 1041 may be provided as a pair. In this case, one electrode may function as a detection electrode for measuring the concentration of the target biological material in the body fluid, and the other electrode may function as a reference electrode for measuring a reference value of the target biological material.

As such, when the biosensor 104 is disposed inside the detection member 101', that is, in the hollow 1011, the biosensor 104 is not exposed to the outside of the detection member 101', so the invasive process damage can be prevented. In addition, when the biosensor 104 is directly disposed in the hollow 1011 , since it directly contacts the target biological material among the body fluids introduced into the hollow 1011 , the information on the target biological material is more accurate than that of an indirect measurement method. can be sensed.

8 is a partial perspective view of a drug injection device according to an embodiment, FIG. 9 is a cross-sectional view taken along line IX-IX of FIG. 8, and FIG. 10 is a cross-sectional view taken along line IX-IX of FIG.

8 to 9 , the needle head 20 of the drug injection device according to an embodiment may include a support 203 , a detection member 201 and an injection member 202 .

The support part 203 may be connected to the main body and support the detection member 201 and the injection member 202 .

The detection member 201 may be inserted into the invasive site in the skin and perform a function of extracting body fluid from the invasive site. The detection member 201 may have a longitudinal direction protruding from the support part 203 in one direction. The detection member 201 may include a hollow 2011 formed therein along the longitudinal direction. A plurality of pores 2012 communicating with the hollow 2011 may be formed on the surface of the detection member 201 . The plurality of pores 2012 may allow the body fluid outside the detection member 201 to penetrate into the hollow 2011 . In this case, the void 2012 may prevent the material inside the hollow 2011 from being reversely transmitted to the outside of the detection member 201 .

The injection member 202 may protrude from the support part 203 to have a longitudinal direction parallel to the detection member 201 . The injection member 202 may be disposed inside the detection member 201 , that is, in the hollow 2011 of the detection member 201 . Based on a cross section perpendicular to the longitudinal direction, the injection member 202 may be located inside the detection member 201 as shown in FIG. 9 . In this case, the injection member 202 may have a circular cross-sectional shape coaxial with the detection member 201 . The injection member 202 may include an injection hole 2021 passing through the interior in the longitudinal direction. Through the injection hole 2021, the injection member 202 may inject the drug into the invasive site.

Since the detection member 201 and the injection member 202 have parallel longitudinal directions, they can be simultaneously inserted into the user's body. That is, the detection member 201 and the injection member 202 can be inserted into the user's body through a single invasion. Accordingly, the function of extracting the bodily fluid sample through the detection member 201 and the function of injecting the drug through the injection member 202 can be performed with only one invasion. According to this structure, since the extraction of the user's body fluid and the drug injection are performed through a separate member, mixing of the drug and the body fluid sample can be prevented. In addition, since the number of invasions for performing each function is limited to one, discomfort or pain felt by the user during the invasion process can be minimized.

Referring to FIG. 10 , the biosensor 204 may be disposed inside the hollow 2011 of the detection member 201 . The biosensor 204 may sense information on the target biological material by reacting with a target biological material, for example, glucose, among the bodily fluid sample introduced into the hollow 2011 . The biosensor 204 may include a reaction layer 2042 including an enzyme that reacts with a target biomaterial, and a sensing electrode 2041 connected to the reaction layer 2042 and generating an electrical signal according to the reaction of the enzyme. have.

The reaction layer 2042 may be applied to the outer surface of the injection member 202 . Since the injection member 202 is disposed inside the detection member 201 , that is, in the hollow 2011 through which the bodily fluid sample is introduced, the reaction layer 2042 may react with the bodily fluid sample introduced into the hollow 2011 . . Since a plurality of voids 2012 communicating with the outer surface are formed on the inner surface of the detection member 201, when the reaction layer 2042 is applied to the outer surface of the injection member 202, the attachment area can be more stably secured. have.

11 is an operation diagram of the drug injection device according to an embodiment, and FIG. 12 is an operation diagram of the drug injection device according to an embodiment.

11 and 12 , the needle head 20 of the drug injection device according to an embodiment may include a support 203 , a detection member 201 and an injection member 202 .

The detection member 201 and the injection member 202 may have parallel longitudinal directions protruding from the support part 203 in one direction. The detection member 201 may include a hollow formed along the longitudinal direction, and a plurality of voids communicating with the hollow may be formed on the outer surface. The detection member 201 may permeate the body fluid of the invasive site into the hollow through the pores formed on the surface.

The injection member 202 may be located inside the detection member 201 . The injection member 202 may include an injection hole passing through the interior in the longitudinal direction. The drug may be injected into the invasive site through the inlet.

By sliding the injection member 202 along the longitudinal direction, the length protruding from the support 203 can be adjusted. Since the injection member 202 occupies a volume inside the hollow of the detection member 201 , the pressure inside the hollow can be adjusted according to the sliding of the injection member 202 . For example, when the injection member 202 slides in the direction of the support part 203 , the pressure in the hollow of the detection member 201 may decrease. In the state in which the detection member 201 is inserted into the invasive site, as shown in FIG. 11 , when the protrusion length d2 of the injection member 202 with respect to the support 203 is reduced according to the sliding of the injection member 202, The pressure inside the hollow of the detection member 201 may decrease, so that the body fluid may flow into the hollow.

On the other hand, the injection member 202 may have a longer protrusion length d3 than the length d1 of the detection member 201 with respect to the support 203 by sliding in the direction of the invasion site as shown in FIG. 12 .

In the invasive procedure, an invasive depth for extracting a bodily fluid sample and an invasive depth for injecting a drug may be different from each other. That is, the depth of penetration into the user's body may vary according to a desired function. In general, as the depth of invasion into the user's body increases, the resistance response of the user's body and the user's pain according to the invasion may increase. The injection member 202 can be inserted into the invasive site to an appropriate depth by sliding to increase the length only when performing a desired function. For example, the injection member 202 may slide to decrease in length as shown in FIG. 11 during a body fluid sample extraction process through the detection member 201 and increase in length as shown in FIG. 12 in the process of injecting a drug.

As a result, the injection member 202 can reduce the user's pain according to the user's body immune response and invasion by adjusting the depth of invasion of the invasive site through the length adjustment through the sliding operation.

13 is a partial perspective view of a drug injection device according to an embodiment.

Referring to FIG. 13 , the needle head 30 of the drug injection device according to an embodiment may include a support 303 , a detection member 301 and an injection member 302 .

The support part 303 may support the detection member 301 and the injection member 302 .

The detection member 301 has a longitudinal direction protruding from the support 303 in one direction, and may include a hollow penetrating the inside along the longitudinal direction. Through the hollow, the detection member 301 may extract a bodily fluid sample from the invasive site. The detection member 301 may include a plurality of pores formed on the outer surface to communicate with the hollow. The body fluid outside the detection member 301 may flow into the hollow through the gap.

The detection member 301 may be used to extract a bodily fluid sample from the invasive site or inject a drug into the invasive site. That is, the detection member 301 may perform both functions of inhaling a bodily fluid sample and injecting a drug through the hollow. For example, a negative pressure may be applied to the hollow of the detection member 301 when a body fluid is sucked, and a positive pressure may be applied to the hollow when a drug is injected.

The injection member 302 may adjust the pressure in the hollow of the detection member 301 . The injection member 302 may be connected to the support part 303 so as to be located inside the detection member 301 . The injection member 302 may slide along the longitudinal direction of the detection member 301 . In other words, according to the sliding operation of the injection member 302 , the pressure inside the hollow of the detection member 301 may be adjusted. For example, the injection member 302 operates to reduce the pressure inside the hollow by moving in the direction of the support 303 in the process of extracting the body fluid sample, and moves toward the invasive site in the process of supplying the drug to the invasive site. By doing so, the pressure in the hollow of the detection member 301 can be increased.

The injection member 302 may be a sensor that detects the concentration of a target biological material, for example, glucose in the user's body fluid introduced into the hollow. In this case, since the detection member 301 surrounds the outside of the injection member 302 , the detection member 301 may not be directly exposed to the outside. Accordingly, damage to the sensor of the injection member 302 in the invasive process can be prevented.

As described above, although the embodiments have been described with reference to the limited drawings, various modifications and variations are possible from the above description by those of ordinary skill in the art. For example, the described techniques are performed in an order different from the described method, and/or the described components of structures, devices, etc. are combined or combined in a different form than the described method, or other components or equivalents are used. Appropriate results can be achieved even if substituted or substituted by

1: drug injection device
10: needle head
11: body
101: detection member

Claims (16)

delete delete delete delete delete delete delete delete a detection member inserted into the invasive site of the skin, a hollow is formed therein, and a void communicating with the hollow is formed on the surface;
an injection member disposed inside the detection member and having a longitudinal direction parallel to the detection member; and
and a biosensor for detecting the concentration of a target biological material from the body fluid introduced into the hollow through the pore.
10. The method of claim 9,
Based on the cross section perpendicular to the longitudinal direction,
The injection member and the detection member have a circular cross-sectional shape having a coaxial, drug injection device.
11. The method of claim 10,

The detection member transmits only the target biological material into a space between the detection member and the injection member through the gap, a drug injection device.
11. The method of claim 10,
The biosensor is
a reaction layer comprising an enzyme that reacts with the target biological material introduced into the detection member; and
A drug injection device connected to the reaction layer and comprising a sensing electrode for generating an electrical signal according to the reaction of the enzyme.
13. The method of claim 12,
The reaction layer is applied to the outer surface of the injection member, drug injection device.
11. The method of claim 10,
The injection member is slidable along the longitudinal direction, drug injection device.
15. The method of claim 14,
A drug injection device for adjusting the internal pressure of the detection member through the sliding operation of the injection member.
11. The method of claim 10,
The injection member includes an injection hole passing through the interior along the longitudinal direction,
A drug injection device for injecting a drug into the invasive site through the injection port.

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