KR102204426B1 - Image acquisition system and image acquisition method using the same - Google Patents

Abstract

The present invention relates to an image acquisition system in which a surgical microscope and an optical coherent tomography apparatus are combined so that a surface image and a tissue tomography image of a lesion site can be acquired at once, and an image acquisition method using the same. An embodiment of the present invention is a light source that irradiates light to an object to be photographed, a microscope that obtains a surface image of the object to be photographed, an optical coherent tomography apparatus that obtains a tomographic image of the object to be photographed, and formed on one surface of the microscope. And a coupling means for coupling the microscope and the optical coherent tomography apparatus, and a mirror connected to the coupling means and capable of adjusting an angle.

Description

Image acquisition system and image acquisition method using the same {IMAGE ACQUISITION SYSTEM AND IMAGE ACQUISITION METHOD USING THE SAME}

The present invention relates to an image acquisition system and an image acquisition method using the same, and in more detail, a surgical microscope and an optical coherent tomography apparatus are combined to obtain a surface image and a tissue tomography image of a lesion at a time. It relates to an image acquisition system and an image acquisition method using the same.

Medical equipment that can acquire tissue images of the inside of the human body includes an X-ray (X-ray) imager, a magnetic resonance imager (MRI), a computed tomography (CT), and an ultrasound imager. Among these, interest in optical coherence tomography (OCT), which has a simpler structure than a computed tomography or magnetic resonance imaging device, and can provide a higher resolution than an ultrasonic imaging device, has recently been rapidly increasing.

Optical Coherence Tomography (OCT) is a high-tech medical device that examines tomography images and cross-sections of living tissues. It transmits light and uses the time difference of the light reflected in the tissue to obtain a tomography image of high resolution. Refers to the device to be obtained. In general, OCT is a high-definition imaging system that combines light with low coherence with an interferometer to generate a tissue cross-sectional image of about 10 μm resolution.

Meanwhile, since a surgical microscope is composed only of a light source and various lenses that provide light, there is a limitation in providing only a surface image of a lesion area. Therefore, in the case of using the optical coherent tomography apparatus together with a surgical microscope in surgery, it is possible to effectively analyze subtle pathological changes within the lesion by acquiring a tissue image as well as a surface image of the lesion.

For example, in the process of laryngeal microsurgery, if the surface of the laryngeal lesion is observed under a microscope, and in addition, the process of obtaining a biological tissue image of the laryngeal lesion using an optical coherent tomography device is performed, effectively performing laryngeal microsurgery. can do.

However, in general, both the optical coherence tomography apparatus and the surgical microscope are large and expensive, and pain is accompanied when observing a lesion site inside the human body such as the larynx using them. Accordingly, obtaining a surface image and a tomography image of a lesion site by using an optical coherent tomography apparatus and a surgical microscope separately has a problem in terms of cost and time. In addition, there is a problem that the patient's pain is doubled because it requires two image acquisition processes.

International Publication WO-1999-059016, 1999-11-18

The present invention was conceived to solve the above problems, and the technical problem to be achieved by the present invention is that an optical coherent tomography apparatus is combined with a surgical microscope to obtain a surface image and a tissue tomography image of a lesion site at once. It is to provide a type of image acquisition system.

Another technical problem to be achieved by the present invention is to provide an image acquisition method capable of acquiring a surface image and a tissue tomography image of a lesion area at once using an image acquisition system in which an optical coherent tomography device is combined with a surgical microscope. To provide.

The technical problem to be achieved by the present invention is not limited to the technical problems mentioned above, and other technical problems that are not mentioned can be clearly understood by those of ordinary skill in the technical field to which the present invention belongs from the following description. There will be.

In order to solve the above technical problem, an embodiment of the present invention includes a light source that irradiates light to an object to be photographed, a microscope that obtains a surface image of the object to be photographed, and optical coherence tomography to obtain a tomographic image of the object to be photographed. It provides an image acquisition system including an apparatus, a coupling means formed on one surface of the microscope and coupling the microscope and the optical coherent tomography apparatus, and a mirror connected to the coupling means and capable of adjusting an angle.

In an embodiment of the present invention, further comprising an exposure means for exposing the object to be photographed existing inside the human body so that the microscope and the optical coherent tomography apparatus obtain a surface image and a tomography image of the object, respectively. can do.

In one embodiment of the present invention, the exposure means may be a laryngoscope.

In an embodiment of the present invention, the photographing unit of the microscope is formed in a photographing direction so as to face the horizontal direction of the object, and the photographing unit of the optical coherent tomography apparatus is in a direction perpendicular to the photographing direction of the photographing unit of the microscope. When the photographing direction is formed and the microscope photographs the photographing object, the mirror is inclined at a predetermined angle so that it disappears from the field of view of the microscope, and the optical coherent tomography apparatus photographs the photographing object, the The mirror may be inclined at a specific angle so that the shape of the object to be photographed is reflected and incident on the photographing unit of the optical coherent tomography apparatus.

In an embodiment of the present invention, a display device that overlaps or separates and displays a surface image of the object to be photographed obtained by the microscope and a tomographic image of the object to be photographed obtained by the optical coherent tomography apparatus may be further included. I can.

In one embodiment of the present invention, when a predetermined area is displayed in the surface image or the tomography image, the display device may display the same area as the predetermined area in the tomographic image or the surface image, respectively.

In addition, another embodiment of the present invention for solving the above technical problem is a microscope, an optical coherent tomography apparatus coupled to the microscope, the microscope and the optical coherent tomography apparatus through angle adjustment An image acquisition method using an image acquisition system including a mirror for acquiring and a display device for displaying an image acquired by the microscope and the optical coherent tomography apparatus, wherein (a) the control unit comprises the microscope and the optical interference Matching the field of view of the sexual tomography apparatus, (b) obtaining a surface image of the surgical object by the control unit using the microscope, and obtaining a tomography image of the surgical object using the optical coherent tomography apparatus And (c) the controller displays the surface image and the tomography image on the display device.

In another embodiment of the present invention, in the step (a), the control unit aligns the optical axis of the microscope and the optical coherent tomography apparatus by matching the focus of the microscope and the optical coherent tomography apparatus to the same sample. Forming a look-up table configured to match the magnification information of the microscope and magnification information of the optical coherent tomography apparatus by the control unit, and the control unit converts magnification information of the microscope into the optical coherent tomography It may include a process of setting the magnification of the optical coherent tomography apparatus according to the magnification information of the microscope transmitted to the photographing apparatus and transmitted using the look-up table.

In another embodiment of the present invention, in the step (b), the controller tilts the mirror at a predetermined angle to disappear from the view of the microscope, and then acquires a surface image of the object to be photographed using the microscope. And, after the controller tilts the mirror at a specific angle so that the shape of the object to be photographed is reflected by the mirror and incident on the photographing unit of the optical coherent tomography apparatus, the optical coherent tomography apparatus It may include a process of obtaining a tomography image of the object to be captured.

In another embodiment of the present invention, the step (c) is a step in which the control unit superimposes or separates the surface image and the tomographic image on the display device, and the display device includes the surface image or the tomographic image When a predetermined area is displayed in the tomography image or the surface image, the same area as the predetermined area may be displayed.

According to the present invention, an optical coherent tomography device can be attached to and detached from a surgical microscope, and a surface image and a tissue image of a lesion site are used using an image acquisition system in which an optical coherent tomography device is combined with the surgical microscope. It is possible to obtain all at once, and accordingly, it is possible to perform the surgery effectively.

In addition, according to the present invention, using an optical coherent tomography apparatus having a long working distance, it is possible to obtain a high-resolution image of the microstructure of the lesion site, and to effectively diagnose the disease at the lesion site at an early stage, and after surgery. It is possible to immediately diagnose the presence of lesions at the surgical site.

The effects of the present invention are not limited to the above effects, and should be understood to include all effects that can be inferred from the configuration of the invention described in the detailed description or claims of the present invention.

1 is a block diagram showing the configuration of an image acquisition system according to an embodiment of the present invention.
2 is a schematic diagram schematically showing a partial configuration of an image acquisition system according to an embodiment of the present invention.
3 is a diagram illustrating a configuration diagram applicable to an image acquisition system according to an embodiment of the present invention.
4 and 5 are diagrams illustrating an analysis result of a photographed object photographed using an image acquisition system according to an embodiment of the present invention.
6 is a flowchart illustrating a procedure of an image acquisition method using an image acquisition system according to another embodiment of the present invention.
7 is a diagram showing a detailed process of step (a) of the image acquisition method shown in FIG. 6.
FIG. 8 is a diagram illustrating a detailed process of step (b) of the image acquisition method shown in FIG. 6.

Hereinafter, the present invention will be described in detail with reference to the accompanying drawings. However, the present invention may be implemented in various different forms, and therefore is not limited to the embodiments described herein. In addition, the accompanying drawings are for easy understanding of the embodiments disclosed in the present specification, and the technical idea disclosed in the present specification is not limited by the accompanying drawings, and all modifications included in the spirit and scope of the present invention It should be understood to include water, equivalents or substitutes. In the drawings, parts irrelevant to the description are omitted in order to clearly describe the present invention, and the size, shape, and shape of each component shown in the drawings may be variously modified, and for the same/similar parts for the entire specification The same/similar reference numerals are attached.

The suffixes "module" and "unit" for components used in the following description are given or used interchangeably in consideration of only the ease of preparation of the specification, and do not have meanings or roles that are distinguished from each other by themselves. In addition, in describing the embodiments disclosed in the present specification, when it is determined that a detailed description of related known technologies may obscure the subject matter of the embodiments disclosed in the present specification, the detailed description thereof has been omitted.

Throughout the specification, when a part is said to be "connected (connected, contacted, or bonded)" with another part, it is not only "directly connected (connected, contacted, or bonded)", but also another member in the middle. It also includes the case of being "indirectly connected (connected, contacted or bonded)" between them. In addition, when a part is said to "include (equipment or prepare)" a certain component, it does not exclude other components, but may further "include (equip or prepare)" other components unless otherwise stated. Means you can.

The terms used in the present specification are only used to describe specific embodiments, and are not intended to limit the present invention. The expression in the singular includes a plurality of expressions unless the context clearly indicates otherwise, and components implemented in a distributed manner may be implemented in a combined form unless there is a specific limitation. In this specification, terms such as "comprise" or "have" are intended to designate the presence of features, numbers, steps, actions, components, parts, or a combination thereof described in the specification, but one or more other features. It is to be understood that the presence or addition of elements or numbers, steps, actions, components, parts, or combinations thereof, does not preclude in advance.

1 is a block diagram showing the configuration of an image acquisition system (hereinafter, “image acquisition system 100”) according to an embodiment of the present invention, and FIG. 2 is a schematic diagram of a partial configuration of the image acquisition system 100 It is a schematic diagram shown.

Referring to FIG. 1, the image acquisition system 100 includes a microscope 120 that obtains a surface image of an object to be photographed, an optical coherent tomography apparatus 130 that obtains a tomographic image of an object to be photographed, and one surface of the microscope 120. It is formed and includes a coupling means 140 for coupling the microscope 120 and the optical coherent tomography apparatus 130, and a mirror 150 connected to the coupling means 140 and capable of adjusting an angle, and It may further include a light source 110 for irradiating light.

In addition, as shown in FIG. 2, the photographing unit of the microscope 120 is formed in a photographing direction so as to face the horizontal direction of the object, and the photographing unit of the optical coherent tomography apparatus 130 A photographing direction may be formed in a vertical direction. The photographing unit of the microscope 120 and the photographing unit of the optical coherent tomography apparatus 130 may be lenses to which light reflected from the object to be photographed is incident, respectively.

Here, the mirror 150 may be tilted at a predetermined angle so that it disappears from the field of view of the microscope 120 when the microscope 120 photographs the object to be photographed, and the optical coherent tomography apparatus 130 photographs the object to be photographed. In this case, it may be inclined at a specific angle so that the shape of the object to be photographed is reflected and incident on the photographing unit of the optical coherent tomography apparatus 130. In addition, the mirror 150 may be connected to the lower end of the coupling means 140, but is not limited thereto.

For example, the mirror 150 may be formed so as to be in close contact with the imaging unit of the optical coherent tomography apparatus 130 horizontally when the microscope 120 photographs the object to be photographed to obtain a surface image. When the photographing apparatus 130 photographs the photographing object and obtains a tomography image, it may be tilted at an angle of about 45 degrees so that the light reflected from the photographing object may enter the photographing unit of the optical coherent tomography apparatus 130.

Meanwhile, referring to FIG. 3 showing a configuration diagram applicable to the image acquisition system 100, the optical coherent tomography apparatus 130 includes a Swept Source Laser, one or more couplers, one or more circulators, one or more mirrors, and one or more. It may be formed of a collimation lens, WDM coupler, beam expander, galvanometer, etc., but is not limited thereto. In addition, the optical coherence tomography apparatus 130 may be connected to a dual balanced detector, a digitizer, a computer, a visible (guide) laser, and the like.

As an embodiment of the image acquisition system 100, the coupling means 140 may include one or more panels attached to the microscope 120 and a mounting hole in which the optical coherent tomography apparatus 130 is mounted. In addition, the optical coherent tomography apparatus 130 may be coupled to the coupling means 140 so that the lens of the optical coherent tomography apparatus 130 is in a vertical direction with the lens of the microscope 120. The coupling means 140 includes a first panel having one side attached to the microscope 120, and a second panel and a second panel having one side attached to the upper side of the other side of the first panel and formed to be smaller than the first panel. A third panel attached to the other surface, a holder connected to extend in the vertical direction of the third panel, and including a mounting hole in which the optical coherent tomography apparatus 130 is mounted, and attached to the lower side of the other surface of the first panel However, it may include a fourth panel formed with “b” and a fifth panel attached to the bottom of the fourth panel.

Referring back to FIG. 1, the image acquisition system 100 displays a surface image of an object to be captured by the microscope 120 and a tomography image of the object to be captured by the optical coherent tomography apparatus 130 by overlapping or dividing it. A display device 160 may be further included.

In this regard, referring to FIGS. 4 to 7 shown to describe the analysis result of an object captured using the image acquisition system 100, the display device 160 is a surface image acquired by the microscope 120. Alternatively, when a predetermined region is displayed in the tomography image obtained by the optical coherent tomography apparatus 130, the same region as the predetermined region may be displayed in the tomography image or the surface image, respectively.

Specifically, FIG. 4 is a surface image 401 of the microscope 120 obtained by photographing an excised dog's larynx (vocal cord) using the image acquisition system 100, and a tomography image of the optical coherent tomography apparatus 130 (402; 403; 404; 405;).

Referring to FIG. 5, when moving a pointer (red part) on the tomographic image 402 of the axial plane of FIG. 5 to display several parts, a coronal plane 403 and a sagittal plane plane) 404, and in real time in the 3D image 405, the same area as the portion displayed in the tomographic image 402 of the axial plane is displayed.

Image Acquisition System In addition, the image acquisition system 100 exposes the object to be photographed inside the human body so that the microscope 120 and the optical coherent tomography apparatus 130 obtain a surface image and a tomography image of the object, respectively. It may further include an exposure means (not shown). In this case, the exposure means may be formed in a mirror-like shape, and the object to be photographed may be a vocal cord or larynx region or a peripheral region thereof.

For example, the exposure means may be a laryngoscope 170. The laryngoscope 170 is formed in the form of a head mirror that is attached to the observer's forehead and reflects light into the mouth of the observer, and a long bag with a mirror at the end. It receives the light reflected from the head mirror and sends it to the larynx while reflecting the shape of the larynx. It may include a pharyngoscope.

In this way, when the image acquisition system 100 includes the laryngoscope 170, the working distance of the microscope 120 is increased, and a surface image and a tomographic image of the larynx can be acquired at once, so that laryngeal surgery can be effectively performed. , Using an optical coherent tomography apparatus having a long working distance, it is possible to obtain a high-resolution image of the microstructure of tissues inside the human body, such as the larynx, to diagnose laryngeal diseases early and effectively, You can immediately diagnose whether the lesion remains.

In addition, conventionally, diseases in lesions such as the larynx were diagnosed and treated with expensive equipment such as MRI or CT, but when the image acquisition system 100 is used, optical coherence tomography, which is relatively inexpensive compared to MRI or CT The device can be used to diagnose or treat a disease in a lesion area such as the larynx at low cost. In addition, unlike the method of determining whether there is a disease in the larynx by performing anesthesia and inserting a laryngoscope directly into the larynx, the image acquisition system 100 has the advantage of being able to diagnose a disease in a lesion area such as the larynx without anesthesia. .

The image acquisition system 100 described so far may include a separate control unit (not shown) for controlling the operation of each component, and the control unit may be a PC-type terminal capable of communication, and the control unit Accordingly, functions of the above-described components may be implemented.

6 is a flowchart showing a procedure of an image acquisition method using an image acquisition system according to another embodiment of the present invention, and FIG. 7 is a diagram showing a detailed process of step (a) of the image acquisition method shown in FIG. 6 And FIG. 8 is a diagram illustrating a detailed process of step (b) of the image acquisition method shown in FIG. 6.

An image acquisition method using an image acquisition system according to another embodiment of the present invention is an image acquisition method using the image acquisition system 100 described with reference to FIGS. 1 to 5 above. Hereinafter, the content overlapping with the above description It should be omitted.

Referring to FIG. 6, an image acquisition method using an image acquisition system according to another embodiment of the present invention includes a microscope, an optical coherent tomography apparatus coupled to the microscope, and the optical coherent tomography through angle adjustment. As an image acquisition method using an image acquisition system including a mirror allowing an apparatus to acquire an image of an object to be photographed, a display device for displaying the image acquired by the microscope and the optical coherent tomography apparatus, and a control unit for controlling them, , (a) step of matching the field of view of the microscope and the optical coherent tomography apparatus by the control unit (S610), (b) the control unit acquires a surface image of the object to be operated using the microscope, and the optical interference Acquiring a tomography image of the surgical object using a gender tomography apparatus (S620), and, (c) the control unit displaying the surface image and the tomography image on the display device (S630). .

Referring to FIG. 7, in the step (a), the control unit sets the focus of the microscope and the optical coherent tomography apparatus to the same sample to match the optical axis of the microscope and the optical coherent tomography apparatus ( S611), and the process of forming a look-up table configured to match the magnification information of the microscope and magnification information of the optical coherent tomography apparatus (S612), and the controller transmits magnification information of the microscope to the optical A process of setting the magnification of the optical coherent tomography apparatus according to the magnification information of the microscope transmitted to the coherent tomography apparatus and transmitted using the lookup table (S613).

Further, referring to FIG. 8, the step (b) is a process in which the controller tilts the mirror at a predetermined angle so that it disappears from the field of view of the microscope, and then acquires a surface image of the object to be photographed using the microscope. (S621), and, after the controller tilts the mirror at a specific angle so that the shape of the object to be photographed is reflected by the mirror and incident on the photographing unit of the optical coherent tomography apparatus, the optical coherent tomography apparatus is A process of acquiring a tomography image of an object to be photographed by using (S622) may be included.

In addition, step (c) (S630) may be a step in which the control unit superimposes or separates the surface image and the tomographic image on the display device, and the display device When an area is displayed, the same area as the predetermined area may be displayed in the tomographic image or the surface image, respectively.

As an implementation example of the above-described image acquisition method, the image acquisition method may include the following preparation process and operation process.

First, as a preparation process, a sample target is prepared in order to match the field of view of the microscope and the optical coherent tomography apparatus.

Next, by measuring the sample target with a microscope, the focus of the microscope is set. Here, in order to focus the microscope, the center of the sample target is positioned at the FOV center of the microscope.

Next, the optical coherent tomography apparatus is focused by measuring the sample target with the optical coherent tomography apparatus. Here, in order to focus the optical coherent tomography apparatus, the center of the sample target is positioned at the FOV center of the optical coherent tomography apparatus.

Next, the optical axis of the microscope and the optical coherent tomography apparatus are matched using the sample target. In order to implement this, the optical coherent tomography apparatus may have a tilt function.

Next, in order to match the field of view of the microscope that changes according to the magnification of the microscope and the field of view of the optical coherent tomography apparatus, a lookup table is constructed by obtaining the magnification value of the optical coherent tomography field suitable for the microscope magnification through a calibration process. do. Here, when the magnification of the microscope is changed, the size of the field of view of the microscope is also changed.

Next, the currently set magnification information and field of view information (image information) are obtained from the microscope and input to the optical coherent tomography apparatus.

Next, the optical coherent tomography apparatus stores magnification, field of view, and focus information of the optical coherent tomography apparatus in the above lookup table by referring to the magnification and field information of the microscope.

Thereafter, as an operation process, the field information and magnification information obtained from the microscope are transmitted to the optical coherent tomography apparatus.

Next, the optical coherent tomography apparatus sets the magnification, focus, and field of view of the optical coherent tomography apparatus by referring to the magnification information of the microscope and the lookup table above. Accordingly, the field of view of the microscope and the field of view of the optical coherent tomography apparatus are matched.

Next, the mirror mounted on the optical coherent tomography apparatus is unfolded.

Next, the object to be photographed is photographed by the optical coherent tomography apparatus in the entire field of view of the optical coherent tomography apparatus or in a partial region arbitrarily set by the user.

Next, an image obtained from a microscope and an image obtained from an optical coherent tomography apparatus are displayed on a single display device. Here, as described above, the single display device may be superimposed on a microscope image to display an optical coherent tomography device image, or may be divided into a microscope image and an optical coherent tomography device image. In addition, if an arbitrary position and region are selected in the microscope image, the same position and region are also displayed in the optical coherent tomography apparatus image. Through this function, the user can view the area under the surface of the lesion area that cannot be viewed with a microscope image as an image of the optical coherent tomography apparatus. In addition, it is possible to accurately mark the location and area of the image by using a graphic annotation.

The above description of the present invention is for illustrative purposes only, and those of ordinary skill in the art to which the present invention pertains can understand that it is possible to easily transform it into other specific forms without changing the technical spirit or essential features of the present invention will be. Therefore, it should be understood that the embodiments described above are illustrative in all respects and not limiting. The scope of the present invention is indicated by the claims to be described later, and all changes or modified forms derived from the meaning and scope of the claims and their equivalent concepts should be interpreted as being included in the scope of the present invention.

Claims (10)

A microscope that acquires a surface image of an object to be photographed;
An optical coherent tomography apparatus for obtaining a tomography image of the object to be captured;
A coupling means formed on one surface of the microscope to couple the microscope and the optical coherent tomography apparatus; And
An image acquisition system comprising a mirror connected to the coupling means and adjustable in angle,
A photographing direction is formed so that the photographing unit of the microscope faces a horizontal direction of the object to be photographed,
The photographing unit of the optical coherent tomography apparatus has a photographing direction perpendicular to the photographing direction of the photographing unit of the microscope,
When the microscope photographs the object to be photographed, the mirror is inclined at a predetermined angle to disappear from the field of view of the microscope,
When the optical coherent tomography apparatus photographs the photographing object, the mirror is inclined at a specific angle so that the shape of the photographing object is reflected and incident on the photographing unit of the optical coherent tomography apparatus. .
The method of claim 1,
An image acquisition system comprising: an exposure means for exposing the object existing inside the human body so that the microscope and the optical coherent tomography apparatus obtain a surface image and a tomography image of the object, respectively.
The method of claim 2,
The image acquisition system, wherein the exposure means is a laryngoscope.
The method of claim 1,
The coupling means is an image acquisition system comprising at least one panel attached to the microscope and a mounting hole through which the optical coherent tomography apparatus is mounted.
The method of claim 1,
And a display device that overlaps or separates and displays the surface image of the object to be captured by the microscope and the tomography image of the object to be captured by the optical coherent tomography apparatus.
The method of claim 5,
The display apparatus, when a predetermined area is displayed in the surface image or the tomography image, displays the same area as the predetermined area in the tomographic image or the surface image, respectively.
A microscope, an optical coherent tomography apparatus coupled to the microscope, a mirror for allowing the microscope and the optical coherent tomography apparatus to acquire an image of an object through angle adjustment, and the microscope and the optical coherent tomography apparatus An image acquisition method using an image acquisition system including a display device displaying an acquired image and a control unit for controlling them,
(a) the control unit matching the field of view of the microscope and the optical coherent tomography apparatus;
(b) obtaining, by the controller, a surface image of the surgical object using the microscope, and obtaining a tomographic image of the surgical object using the optical coherent tomography apparatus; And
(c) the control unit displaying the surface image and the tomographic image on the display device, the method comprising:
The step (a),
A process in which the controller sets the focus of the microscope and the optical coherent tomography apparatus to the same sample to match the optical axes of the microscope and the optical coherent tomography apparatus,
A process in which the control unit forms a look-up table configured to match magnification information of the microscope and magnification information of the optical coherent tomography apparatus, and,
The control unit transmits the magnification information of the microscope to the optical coherent tomography apparatus and sets the magnification of the optical coherent tomography apparatus according to the magnification information of the microscope transmitted using the look-up table. An image acquisition method, characterized in that.
The method of claim 7,
The image acquisition system further comprises a coupling means formed on one surface of the microscope to combine the microscope and the optical coherent tomography apparatus.
The method of claim 7,
The step (b),
After the control unit tilts the mirror at a predetermined angle so that it disappears from the field of view of the microscope, the process of obtaining a surface image of the object to be photographed using the microscope, and,
After the controller tilts the mirror at a specific angle so that the shape of the object to be photographed is reflected by the mirror and incident on the photographing unit of the optical coherent tomography apparatus, the photographing object is performed using the optical coherent tomography apparatus. An image acquisition method comprising the process of obtaining a tomography image of.
The method of claim 7,
The step (c),
A step in which the control unit overlaps or separates and displays the surface image and the tomography image on the display device,
The display apparatus, when a predetermined area is displayed in the surface image or the tomography image, displays the same area as the predetermined area in the tomographic image or the surface image, respectively.

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