JPS5767602A - Preparation of pullulan for expanding plasma - Google Patents
Preparation of pullulan for expanding plasmaInfo
- Publication number
- JPS5767602A JPS5767602A JP14295380A JP14295380A JPS5767602A JP S5767602 A JPS5767602 A JP S5767602A JP 14295380 A JP14295380 A JP 14295380A JP 14295380 A JP14295380 A JP 14295380A JP S5767602 A JPS5767602 A JP S5767602A
- Authority
- JP
- Japan
- Prior art keywords
- pullulan
- molecular weight
- average molecular
- weight
- fraction
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
PURPOSE: To obtain a pullulan in high yield having a specific molecular weight useful as an plasma expander for preventing and remedying traumatic shocks caused by bleeding, excellent in safety, obtained by hydrolyzing a raw material pullulan partially, followed by fractionation.
CONSTITUTION: A raw material pullulan is partially hydrolyzed with an acid (lactic acid, etc.) or an enzyme (e.g., α-amylase, etc.), and fractionated with a hydrophilic organic solvent (e.g., methanol, etc.), to give a pullulan fraction, which is decolored with active carbon, etc. and desalted. The fraction is filtered by a membrane filter, concentrated of further dried, to give the desired pullulan having a ratio of weight-average molecular weight to number-average molecular weight of ≤1.5 and a weight-average molecular weight of 30,000W90,000.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP14295380A JPS5767602A (en) | 1980-10-15 | 1980-10-15 | Preparation of pullulan for expanding plasma |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP14295380A JPS5767602A (en) | 1980-10-15 | 1980-10-15 | Preparation of pullulan for expanding plasma |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP15613481A Division JPS57141401A (en) | 1981-10-02 | 1981-10-02 | Production of pullulan with narrowed molecular weight distribution |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5767602A true JPS5767602A (en) | 1982-04-24 |
JPS6121481B2 JPS6121481B2 (en) | 1986-05-27 |
Family
ID=15327485
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP14295380A Granted JPS5767602A (en) | 1980-10-15 | 1980-10-15 | Preparation of pullulan for expanding plasma |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5767602A (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS57141401A (en) * | 1981-10-02 | 1982-09-01 | Hayashibara Biochem Lab Inc | Production of pullulan with narrowed molecular weight distribution |
US5518902A (en) * | 1992-08-20 | 1996-05-21 | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo | High pullulan content product, and its preparation and uses |
-
1980
- 1980-10-15 JP JP14295380A patent/JPS5767602A/en active Granted
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS57141401A (en) * | 1981-10-02 | 1982-09-01 | Hayashibara Biochem Lab Inc | Production of pullulan with narrowed molecular weight distribution |
JPH0248561B2 (en) * | 1981-10-02 | 1990-10-25 | Hayashibara Seibutsu Kagaku Kenkyusho Kk | |
US5518902A (en) * | 1992-08-20 | 1996-05-21 | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo | High pullulan content product, and its preparation and uses |
Also Published As
Publication number | Publication date |
---|---|
JPS6121481B2 (en) | 1986-05-27 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
JPS5296791A (en) | Preparation of composition including enzymes or microorganisms | |
JPS5386090A (en) | Preparation of l-lysine by fermentation | |
JPS5767602A (en) | Preparation of pullulan for expanding plasma | |
JPS5391189A (en) | Preparation of d-n-carbamoyl-alpha-amino acids | |
JPS5466604A (en) | Polysaccharide m-30-c | |
JPS5329978A (en) | Cultivation medium | |
JPS55125101A (en) | Preparation of graft-modified starch | |
JPS52114092A (en) | Preparation of l-arginine by fermentation process | |
KR910011164A (en) | Manufacturing method of instant ginseng soft capsule | |
JPS5341482A (en) | Preparation of marine methanol-assimilable bacterial cells | |
JPS57141401A (en) | Production of pullulan with narrowed molecular weight distribution | |
JPS5439952A (en) | Method of producing purified water | |
JPS5648891A (en) | Preparation of polysaccharide | |
JPS5779863A (en) | Preparation of crab meatlike food from krill | |
KR900016458A (en) | Novel strain Saccharomyces, Saccharomyces cerevisiae JY10035 and ethanol production method using the same | |
JPS55108293A (en) | Production of proteopolysaccharide with antitumorigenic activity | |
JPS5234984A (en) | Production of adenine derivatives by fermentation process | |
JPS5362895A (en) | Preparation of 5'-inosinic acid by fermentation | |
JPS5394023A (en) | Preparation of anti-tumor polysaccharide | |
JPS55114288A (en) | Production of cholesterol esterase | |
JPS533592A (en) | Separation of protein from yeast cells | |
JPS5394021A (en) | Preparation of anti-tumor polysaccharide | |
JPS5750886A (en) | Novel l-arginine oxydase, its preparation, and bacteria capable of producing the same | |
JPS5542564A (en) | Production of antitumorigenic substance | |
JPS5394020A (en) | Preparation of anti-tumor polysaccharide |