JPS57206665A - Novel 2,4(1h,3h)-quinazolinedione derivative - Google Patents
Novel 2,4(1h,3h)-quinazolinedione derivativeInfo
- Publication number
- JPS57206665A JPS57206665A JP9157281A JP9157281A JPS57206665A JP S57206665 A JPS57206665 A JP S57206665A JP 9157281 A JP9157281 A JP 9157281A JP 9157281 A JP9157281 A JP 9157281A JP S57206665 A JPS57206665 A JP S57206665A
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- halogen
- compound
- quinazolinedione
- novel
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
NEW MATERIAL:The 2,4(1H,3H)-quinazolinedione derivative of formulaI(R1 and R3 are alkyl; R2 is alkoxycarbonyl; R1WR3 bond to the 5, 6 and 7-positions or 6, 7 and 8-positions of the nucleus; R4 is H, halogen, alkyl, CF3, or nitro; X is alkylene; Y is N or CH; R5WR7 are H, halogen, alkyl, or alkoxy; R8 and R9 are H or alkyl; m is 0W3; n is 0 or 1).
EXAMPLE: 6-Ethoxycarbonyl-5,7-diemthyl-1-[ 2-( 4-phenylpiperidino )ethyl ]-3-( o- chloropheyl)-2,4(1H,3H)-quinazolinedione.
USE: A vasodilator, a blood flow improving agent, a hypotensor, and an antiarteriosclerotic agent.
PROCESS: The compound of formulaIcan be prepared by reacting the compound of formula II with the compound of formula III (Z is halogen) in the presence of an alkali metal hydride or an alkali metal amide.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP9157281A JPS57206665A (en) | 1981-06-16 | 1981-06-16 | Novel 2,4(1h,3h)-quinazolinedione derivative |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP9157281A JPS57206665A (en) | 1981-06-16 | 1981-06-16 | Novel 2,4(1h,3h)-quinazolinedione derivative |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS57206665A true JPS57206665A (en) | 1982-12-18 |
Family
ID=14030236
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP9157281A Pending JPS57206665A (en) | 1981-06-16 | 1981-06-16 | Novel 2,4(1h,3h)-quinazolinedione derivative |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS57206665A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6407116B1 (en) | 1997-09-16 | 2002-06-18 | Takeda Chemical Industries, Inc. | Nitrogenous fused-ring compounds, process for the preparation of the same, and drugs |
-
1981
- 1981-06-16 JP JP9157281A patent/JPS57206665A/en active Pending
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6407116B1 (en) | 1997-09-16 | 2002-06-18 | Takeda Chemical Industries, Inc. | Nitrogenous fused-ring compounds, process for the preparation of the same, and drugs |
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