JPS57206665A - Novel 2,4(1h,3h)-quinazolinedione derivative - Google Patents

Novel 2,4(1h,3h)-quinazolinedione derivative

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Publication number
JPS57206665A
JPS57206665A JP9157281A JP9157281A JPS57206665A JP S57206665 A JPS57206665 A JP S57206665A JP 9157281 A JP9157281 A JP 9157281A JP 9157281 A JP9157281 A JP 9157281A JP S57206665 A JPS57206665 A JP S57206665A
Authority
JP
Japan
Prior art keywords
alkyl
halogen
compound
quinazolinedione
novel
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP9157281A
Other languages
Japanese (ja)
Inventor
Masayuki Ishikawa
Akiko Sugimoto
Masao Eguchi
Fujinori Sasaki
Katsuhiko Goto
Soyao Moriguchi
Hisashi Ebisawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to JP9157281A priority Critical patent/JPS57206665A/en
Publication of JPS57206665A publication Critical patent/JPS57206665A/en
Pending legal-status Critical Current

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  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:The 2,4(1H,3H)-quinazolinedione derivative of formulaI(R1 and R3 are alkyl; R2 is alkoxycarbonyl; R1WR3 bond to the 5, 6 and 7-positions or 6, 7 and 8-positions of the nucleus; R4 is H, halogen, alkyl, CF3, or nitro; X is alkylene; Y is N or CH; R5WR7 are H, halogen, alkyl, or alkoxy; R8 and R9 are H or alkyl; m is 0W3; n is 0 or 1).
EXAMPLE: 6-Ethoxycarbonyl-5,7-diemthyl-1-[ 2-( 4-phenylpiperidino )ethyl ]-3-( o- chloropheyl)-2,4(1H,3H)-quinazolinedione.
USE: A vasodilator, a blood flow improving agent, a hypotensor, and an antiarteriosclerotic agent.
PROCESS: The compound of formulaIcan be prepared by reacting the compound of formula II with the compound of formula III (Z is halogen) in the presence of an alkali metal hydride or an alkali metal amide.
COPYRIGHT: (C)1982,JPO&Japio
JP9157281A 1981-06-16 1981-06-16 Novel 2,4(1h,3h)-quinazolinedione derivative Pending JPS57206665A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP9157281A JPS57206665A (en) 1981-06-16 1981-06-16 Novel 2,4(1h,3h)-quinazolinedione derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP9157281A JPS57206665A (en) 1981-06-16 1981-06-16 Novel 2,4(1h,3h)-quinazolinedione derivative

Publications (1)

Publication Number Publication Date
JPS57206665A true JPS57206665A (en) 1982-12-18

Family

ID=14030236

Family Applications (1)

Application Number Title Priority Date Filing Date
JP9157281A Pending JPS57206665A (en) 1981-06-16 1981-06-16 Novel 2,4(1h,3h)-quinazolinedione derivative

Country Status (1)

Country Link
JP (1) JPS57206665A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6407116B1 (en) 1997-09-16 2002-06-18 Takeda Chemical Industries, Inc. Nitrogenous fused-ring compounds, process for the preparation of the same, and drugs

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6407116B1 (en) 1997-09-16 2002-06-18 Takeda Chemical Industries, Inc. Nitrogenous fused-ring compounds, process for the preparation of the same, and drugs

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