JPH09225008A - Medical liquid preparation apparatus - Google Patents

Abstract

PROBLEM TO BE SOLVED: To achieve a safe and accurate repeated preparation by saving labor, by a method wherein a controller for a preparation pump device is arranged separately from an information processor for information on prescription or the like and a working control signal of the preparation pump device is applied by reading from a reader to avoid artificial mistakes. SOLUTION: A controller 3 for a clean room A applies a command signal to a preparation pump device 1 when it receives medicine information of each medical liquid, patient information, information for prescription or information for operation or control of pumps from a computer 7d (information processor) on the side of an office room C so that the valve of a corresponding suction port alone is opened which corresponds to each kind of medical liquid indicated in a prescription. A label reader 5 reads a previously prepared code chart and sends a working control signal for the preparation pump device 1 to the preparation pump device 1 through the controller 3 while reading the contents of a label, printed by a label printer 6 and stuck on a preparation container 10, by an optically reading system to provide informations on the prescription necessary for the controller 3.

Description

Detailed Description of the Invention

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a chemical liquid preparation device for mixing and filling various chemical liquids such as infusion liquid into a container according to a prescription by an automatic operation instead of manually.

[0002]

2. Description of the Related Art When preparing a medicinal solution having a desired composition according to a patient's prescription such as intravenous infusion or various injections, conventionally, each end of a tube which can be individually opened and closed by a clamp is hung on a hanger. Connected to each of the various liquid medicine containers, join the other end of each tube, and connect to the preparation container such as an infusion bag.While weighing the preparation container, open and close each clamp to obtain the kind of liquid medicine according to the prescription. A fixed amount was poured into the preparation container and mixed. In addition, as another method, the individual liquid medicine containers are weighed first, and the discharging operation is performed so that the predetermined amount according to the prescription remains in each, and then the total remaining amount is transferred to the preparation container to complete the preparation. Methods are also known.

[0003]

In the conventional chemical liquid blending method, since the injection of each chemical liquid into the blending container relies on gravity falling by gravity, it takes time to blend, and the blending result is also manually measured. Since most of the manual work operations such as visual judgment are complicated, the work is complicated to avoid the occurrence of measurement error and the error of confirmation. Furthermore, it is difficult to confirm because it is an essentially transparent chemical solution preparation. Yes, there is a risk that if a wrong label is attached to the mixing container due to an error, it may lead to a serious mistake, and since the label is mostly handwritten, there is a possibility of typographical error or misreading. There was a problem that it lacked objectivity because people also performed such confirmation.

An object of the present invention is to perform labor-saving, safe and accurate repeated preparation even for complicated prescriptions that are subtly different for each patient depending on age, sex, weight, medical condition, etc. It is an object of the present invention to provide a chemical liquid preparation device capable of performing automatic preparation with high efficiency from preparation to completion, including input, inspection, and process check.

[0005]

In order to achieve such an object, the chemical liquid blending device according to the present invention is predetermined in accordance with the opening / closing operation of the valve by the command signal when the operation control signal and the command signal are received. A blending pump device that selectively sucks the drug solution from a plurality of suction ports that receive the supplied type of drug solution and sends the drug solution to the blending container, and the blending container is weighed and fed into the blending container from the blending pump. A weighing device that outputs an electrical measurement signal indicating the weight of the drug solution, an input device for inputting drug information, patient information, prescription information, and operation signals of each drug solution supplied to each suction port, and operation In accordance with the input of the signal, the type of liquid medicine according to the prescription and the prescription amount thereof and the corresponding suction port are specified based on the above information, and the pump operation control corresponding to the specified contents is specified. An information processing device for generating information, a storage device for storing each information input from an input device and pump operation control information designated and generated by the information processing device, and an output for displaying processing contents by the information processing device Apparatus, and at least a part of each of the information and the pump operation control information from the information processing apparatus, and the command signal to open only the valve of the suction port corresponding to each type of liquid medicine according to the prescription. The amount of the drug solution to be fed from the blending pump device to the blending container is given based on the measurement signal from the weighing machine and the theoretical mass value obtained from the specific gravity value and the prescription amount of the designated type of drug solution while being given to the device. A control device and a reading device for giving an operation control signal of the blending pump device to the blending pump through the control device by reading a code table are provided. It is characterized by a door.

In this case, the patient information may include administration contraindicated drug information, and the information processing device displays a warning on the output device based on the administration contraindication drug information and the drug information and / or prescription information. It is also possible to do so.

[0007] The drug information may include unusable information indicating a combination of drugs that are inconvenient for treatment or mixing, and is output to the output device by the information processing device based on the unusable information and the prescription information. It is also possible to display a warning.

Further, the control device may be provided with a label printer which prints a label to be attached to the preparation container in correspondence with the prescription information.

In this case, the control device has a function of inhibiting the operation of the blending pump when the reading result of the label attached to the blending container before the blending by the reading device and the prescription information do not match. Good.

In a preferred embodiment of the invention described below, a compounding pump device, a weigher, a controller,
The reading device is installed in a clean room, and the input device, the information processing device, the storage device, and the output device are configured by an electronic computer system using a personal computer installed outside the clean room. And the control device are connected to each other via a data communication means as an interface, for example, a wired communication system using a cable or, particularly preferably, a wireless communication system such as optical communication or electromagnetic wave communication. Further, the control device in the clean room can be configured by another personal computer like the information processing device.

[0011]

DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS FIG. 1 shows an outline of the system configuration of a drug solution preparing device according to a preferred embodiment of the present invention. In FIG. 1, in a clean room A, a compounding pump device 1, an electronic scale 2 as a weighing machine, a control device 3 including a personal computer, a display device 4, a label reading device 5, and a label printer 6 are installed, and a glass window is provided. In the office B separated from the clean room A by the partition B, a keyboard 7a as an input device, a display device 7b and a printer device 7c as output devices, a computer 7d having a storage device and an information processing device built therein.
And a computer 7d in the office C and a control device 3 in the clean room A are installed.
Are coupled to each other via optical communication couplers 8a and 8b connected to the interface boards so that data communication can be performed through the glass window of the partition wall B.

When receiving the operation control signal and the command signal from the control device 3, the compounding pump device 1 is supplied with a plurality of chemical liquids of a predetermined type according to the opening / closing operation of the built-in valve by the command signal. It is a metering pump that selectively sucks a drug solution from a suction port and sends it out to a preparation container. In the illustrated example, various drug solution package containers 9 suspended on a hanger are connected to a plurality of suction ports by tubes, and a pump discharge port. Is connected to the preparation container 10 via a tube.

The blending container 10 is placed on the measuring table of the electronic scale 2. The electronic balance 2 weighs the blending container 10 to measure the weight of the chemical liquid fed from the blending pump device 1 into the blending container 10. The electric measurement signal shown is sent to the control device 3 through the interface cable.

The control device 3 receives drug information, patient information, prescription information, and pump operation control information of each drug solution from the computer (information processing device) 7d on the office C side, and for each drug solution of the type according to the prescription. A command signal is given to the compounding pump device 1 so as to open only the valve of the corresponding suction port, and based on the measurement signal from the electronic balance 2 and the theoretical mass value obtained from the specific gravity value and the prescribed amount of the specified type of chemical liquid. The amount of the chemical liquid to be sent from the compounding pump device 1 to the compounding container 10 is calculated, and the result is displayed on the display device 4
In addition, the label printer 6 executes a print output including an optical reading code such as a bar code in the form of an affixed label. The sticky label printed by the label printer 6 is stuck on the mixing container 10, and the mixing of the liquid medicine in the mixing container is read by the label reading device 5 with the print code of the label stuck on it, and if the prescription data does not match, it is controlled. The device 3 will operate without error by inhibiting the operation of the pump 1.

The label reading device 5 gives an operation control signal of the blending pump device to the blending pump device 1 through the control device 3 by reading a code table prepared in advance, and at the same time, the label printer 6 prints the blending container 10 for printing. The content of the sticky label stuck on the label is read by an optical reading method, and information about necessary prescription is given to the control device 3.

The computer 7d in the office C receives necessary information from the keyboard 7a, for example, drug information of each drug solution supplied to each suction port of the compounding pump device 1, patient information, prescription information, and the like. Command signals necessary for operation can also be input from the keyboard 7a.
The computer 7d designates the type of liquid medicine according to the prescription, the prescription amount thereof, and the corresponding suction port based on each of the above information in response to the input of the operation command signal, and also generates pump operation control information corresponding to the designated content. Optical communication coupler 8
a, 8b to the control device 3 and also the keyboard 7
The information input from a and the pump operation control information designated and generated by the information processing in the computer are stored in the built-in storage device, and the necessary processing contents are displayed on the display device 7b.
And the management record form is printed out from the printer device 7c.

The chemical liquid preparation operation by the preparation device having the above construction is as follows. That is, after turning on the power of each device, the environment of the computer 7d is set and the setup operation is executed. This work is mainly performed in the office C, and there are registration of drug information and patient information of each drug solution by operating the keyboard 7a and registration of prescription information as a daily work.

In the registration of drug information, formulation classification, component composition, form, and other information of various drug solutions to be used, and unusable information consisting of drug components that are not allowed to be mixed or used in combination with the drug solution. Enter. The registration number of each drug solution is automatically given in sequence, along with the drug name (product name),
As the classification, for example, a basic solution, an amino acid solution, a fat emulsion, an electrolyte solution, a calcium agent, water, or any of the other seven classifications (used to specify the order of mixed injection by a pump) is input.

Further, the specific gravity value of each chemical liquid necessary for accurate weighing calculation based on the measurement result of the weighing device (here, electronic scale) is input, and the pH value, EN ratio, osmotic pressure ratio, etc. are input as necessary. Enter the required information. Type of package (soft bag, glass bottle,
Used to determine pump rotation speeds such as syringes and spike types (low speed, medium speed, high speed) and viscosity correction values Type N: Soft bag, etc. = high speed, type V: glass bottle = medium speed, type L: High-viscosity fat agent = medium speed, type D: mini vial = low speed, type S: syringe = low speed),
Volume (content of the container, subtract from this value when the pump is running, stop the pump when the remaining amount is zero), viscosity correction value (the pump rotation speed of the reference volume with water as 1 and the same amount of each chemical solution) Input the ratio with the pump rotation speed required for the operation.

Since this viscosity correction value needs to be corrected not only by the viscosity of the liquid chemical itself but also by the form of the container when a plurality of types of liquid chemicals are co-injected by the metering pump, it is measured in advance for each drug contained in the container. Is required.
This measurement is performed as follows by operating the pump 1 by the control device 3 in the clean room A under the condition that the pump 1 is correctly calibrated with the liquid medicine in the container whose viscosity correction value is known.

That is, a predetermined amount of the chemical liquid is discharged from the target chemical liquid container by the pump 1, the actual measurement value of the chemical liquid is obtained from the measured value of the electronic scale, and the theoretical weight value is calculated by the controller from the specific gravity value and the discharge amount of the chemical liquid. The viscosity correction value = theoretical value / actual measurement value is calculated by the control device 3 and stored in the storage device.

Furthermore, the composition of each chemical solution (the quantity of the ingredient per 1 mL or the quantity of the ingredient per container), the name of the ingredient, the unit, and the prescription upper limit value are input, and the unusable information corresponding to the chemical solution is entered. , Specific drug components that cause problems in mixing or treatment such as changes in drug effects due to mixing and / or enhancement of side effects and reference numbers (file numbers) of information contents that cause inevitable reasons and other special notes, for example, in advance for each drug name Enter using the data given in. The input drug information is stored in the storage device as drug master data, ingredient list master data, and unusable drug master data.

When registering patient information, the patient identification number (ID
Number), health insurance card number, name and reading, weight,
Enter the gender, date of birth (age), first visit date, ward / room name, prescription doctor, administration repellent drug (select from drug list), disease name, medical history, and other special notes, and store as patient master data. Save to.

Registration of prescription information, which is carried out as a daily work, is executed according to the flow shown in FIG. 2 after the program of the system is activated and the input operator name and the like are input. In the following description, the storage device specifically includes a storage medium such as a hard disk, a floppy disk, an optical disk, and a magneto-optical disk, and the storage information is the patient list master data, drug master data, ingredient list master data described above. It shall be stored as various databases such as.

First, the dispensing number is automatically input or manually input, the dispensing date is input, and the prescription information registration operation is started. In the first step 201, the patient name is entered. Here, enter the patient ID number described in the prescription to be entered, or click the patient list icon displayed on the display device 7b to display the screen. Select the corresponding patient name from the patient name list displayed above. As a result, in step 202, the patient list master is checked, and if there is matching data in the master, necessary patient information such as the patient's name, age, administration repellent drug, and disease name is fetched from the master data. The process proceeds to the next step 204 of inputting the prescription drug name. In the case of a new patient who is not in the patient list master, the process proceeds to step 203, the same patient information registration work as described above is performed, and then the process returns to step 201 to perform the patient name input work again.

When inputting the prescription information, in reality, there is a relatively high proportion of continuous prescriptions having the same content as the previous prescription, so confirmation of differences in medication and prevention of erroneous input and work. In order to improve efficiency, the previous prescription content is displayed in a window on the screen in step 204, the previous prescription content is compared with the prescription content to be used for input in step 205, and when both are the same content, In step 206, the desired content in this window display is clicked on with the mouse, and the prescription information for this time is copied and input. When the copy input is completed, the input data is fetched by clicking the icon based on the display on the screen in step 207.
As a result, the prescribed drug and its prescribed amount are stored as prescription list data. In this way, when the same data as the previous prescription content is fetched in step 207, in step 220, the registration of one prescription information is completed by clicking the new registration icon on the screen.

On the other hand, if the content of the prescription of this time is different from the content of the prescription of the previous time in the screen display in step 205, the process proceeds to step 208 to input the prescription drug name. In this case, the difference between the content of the current prescription and the content of the previous prescription on the screen can be easily confirmed before the input work, and the error of the prescription issuer can be checked.

In step 208, when a drug name to be prescribed is selected from the drug list displayed on the screen, whether or not it is registered in the drug master is checked in step 2
If it is determined in step S09 that it has not been registered, the process proceeds to step 210, the same drug master data registration work as before is performed, and then the process returns to step 208 to again input the prescription drug name. It should be noted that, for the prescription information input work, it is possible to omit most of the keyboard input work by adopting a method of prescription stylization and reading recognition by a scanner, and also to prevent errors due to erroneous input. There is no end.

If the entered drug name is registered, the process proceeds to step 211, and the entered drug is mixed with another drug previously entered by collating with the unusable information in the drug information of the master data. Alternatively, it is confirmed that the combination is not a therapeutically unusable combination. If the medicine is not usable, a warning display is executed in step 212, and this warning is reported to the operator by a buzzer sounding, and
On the display screen, for example, the drug name of the partner who cannot be used and the unreasonable reason, for example, the side effect enhancement type and the information number such as a text name of reference information including the detailed content thereof are displayed.

Step 21 if not a non-usable drug
Then, the process proceeds to step 3, and the collation with the patient information in the master data confirms that the input drug is not the administration repellent drug. Step 214 if repellent
The warning display is executed by the operator, and this warning is also notified to the operator on the display screen and by the buzzer sounding.

If it is determined in step 213 that the drug is not a repellent drug to be administered, the process proceeds to step 215, and the entered drug prescription amount is entered from the ten-key on the keyboard. The component amounts are calculated based on the component list data, and it is confirmed that none of them exceeds the upper limit value.
If there is a component exceeding the upper limit value, a warning display is executed in step 217, and this warning is reported to the operator on the display screen and by the buzzer sounding.

When it is determined in step 216 that there is no component exceeding the upper limit value, it is displayed on the screen,
In step 218, the input data is fetched by clicking the icon based on the display on this screen. As a result, the prescribed drug and its prescribed amount are stored as prescription list data.

When the loading operation is completed in step 218, a display requesting selection of whether to finish the prescription drug input work or continue is displayed on the screen in step 219, and if the continue icon is clicked, the process returns to step 208. Therefore, the same input is repeated for the next drug, and when all the input for each drug described in the prescription is completed in this way, at the end step 220, a new registration icon on the screen is clicked to make one prescription. Complete registration of information.

Each drug solution is enclosed in a drug package container 9, and a label on which information indicating the content is printed by an optical reading code such as a bar code is attached to each package container 9. These chemical solution package containers 9 are carried from the storage into the clean room A and connected to the individual suction ports of the blending pump device 1 by tubes. Which container 9 is connected to which suction port is set by the computer 7d. To do.

In this port setting operation, a port setting window is opened on the display screen of the display device 7b,
This is accomplished by selecting the drug to be assigned from the drug list in the state where the prescription list and the registered drug list are displayed, selecting the suction port to be assigned by number, and clicking the setting icon. As a result, the computer 7d creates port setting information for instructing which medicine package container 9 is connected to which suction port and used medicine information for each prescription.

When the input and registration of each information and the port setting are completed as described above, the computer 7d is instructed to start communication. As a result, necessary information is sent from the computer 7d to the control device 3 in the clean room A via the communication couplers 8a and 8b.

In the dispensing operation in the clean room A, the control device 3 is operated by reading the operation command code by the label reading device 5. That is, a code table of various command contents is prepared in the form of, for example, a bar code, and a desired command signal is given to the control device 3 by reading the code of the necessary command contents with the reading device 5.

First, the reading device 5 gives a command to the control device 3 to cause the label printer 6 to print out the label to be attached to the compounding container 10 corresponding to each prescription based on the prescription information received from the computer 7d. This sticky label contains control information and collation information necessary for compounding in the form of an optical reading code such as a barcode. The pasted label printed by the label printer 6 is pasted on the blending container 10, and the blending of the liquid medicine into the blending container is accurately controlled by the control device 3 by reading the print code of the label pasted on it with the label reading device 5. Will be done.

The controller 3 is operated in the same manner to display the port setting contents on the display device 4 based on the port setting information received from the computer 7d, and the drug information for each combination of the drug package container and the port number. The bar code including the number and the numerical print of the port number are printed out from the label printer 6 in the form of an attached label. The affixed label is affixed to the tube of the port number corresponding to the number printed on the label by the dispensing operator in the clean room A.

The connection work between the medicine package container 9 and each suction port is executed according to the flow shown in FIG. First, in step 301, a port setting diagram is displayed on the screen of the display device 4. Next, when the label attached to the tube is read by the reading device 5 in step 302, the control device 3 determines in step 303 whether or not it is the designated tube, and if it is different, the tube is reconfirmed in step 304. In the case of the designated tube, in step 305, the predetermined drug package container 9 is connected to the tube connected to the suction port according to the port instruction diagram.

Next, in step 306, the label attached to the connected container 9 is read by the reading device 5, and in step 307, the control device 3 determines whether or not the medicine is compatible with the port number. In the case of non-conformity, a display requesting reconfirmation of the connection between the drug package container 9 and the tube is displayed in step 308, and if incorrect connection is avoided by performing confirmation work based on it, the process returns to step 306 again. If they match, the record of the remaining amount of the medicine in the control device 3 is updated from zero to the predetermined amount of the container, and it is determined in step 309 whether or not the inside of the tube is filled with the medicine liquid to discharge the air. If it is necessary to satisfy the condition, the pump is operated in step 310, but if it is not necessary, it is determined in step 311 whether or not there is any remaining tube to be connected, and if any, the process returns to step 301 and the same operation is performed. Repeatedly, if not remaining, the process ends in step 312.

After a predetermined medicine container 9 is connected to each suction port, the port number is designated in order as needed, and the pump 1 is operated to discharge the air in the tube for each medicine. In this case, the port number is specified by reading the command code table by the reading device 5, and a discharge amount command of 0.5 to 50 mL is similarly given by reading the command code table according to the tube volume, and the valve switching of the specified port is performed. The pump 1 is operated so that the chemical solution is filled up to the part. After performing this operation for all ports, proceed to the next calibration operation.

The calibration is an operation for calibrating the volume of the drug solution, which changes depending on the environmental conditions such as the temperature at the time of dispensing, by the theoretical value and the measured value of the weight. This is because the dispensing pump device of the present invention quantifies the discharge amount (capacity) based on the weight measurement value by the electronic balance 2. In the calibration operation, similarly to the above-mentioned viscosity correction value, after the air discharge operation of the tube is completed, water is supplied by designating the port to which the package container serving as the basic liquid for preparation is connected.

First, an empty container such as a graduated cylinder is placed on the electronic scale 2, a calibration start command is read from the command code table, and the control unit 3 is operated to cancel the tare weight from the measured value of the electronic scale 2. deep. Read the port number of the drug solution container that should be calibrated from the command code table, and use the bar code on the code table
The amount of liquid to be fed is instructed within the range of 30 mL to operate the pump 1 to inject it into the graduated cylinder.

The pump 1 discharges the specified amount of the liquid medicine and sends it to the graduated cylinder, and its theoretical mass is the product of the specific gravity of the specified liquid medicine (taken from the medicine master data) and the indicated liquid amount, The measured mass is given by the measured value of the electronic balance 2. The control device 3 determines the correction coefficient f from these values.
= Theoretical mass / actually measured mass is calculated, and in the subsequent dispensing, an operation control signal is set to the pump 1 as a liquid delivery command value to the pump 1 with a value obtained by multiplying the prescription amount for each drug by the correction coefficient f. give.

For example, the indicated chemical liquid is water and the specific gravity is 1, the indicated liquid feeding amount is 10 mL, and the measured mass by the electronic balance is 10.
In the case of 2 g, the correction coefficient f is 10 / 10.2. = 0.980.
Becomes Therefore, 0.980 is added to the prescribed amount of each prescribed drug solution.
The value obtained by multiplying by becomes the corresponding pump discharge amount command value.

When the above preparatory work is completed, dispensing for each prescription is executed. Dispensing operation is performed according to the flow shown in FIG. 4 and FIG. Figure 4 shows the first half of the dispensing flow,
FIG. 5 shows the second half of the subsequent flow. In addition, prior to the start of the dispensing flow, when the previous calibration operation or tube connection work or the dispensing of the preceding prescription, the drug solution that last operated the pump is different from the basic solution that is the main drug on the prescription. , It is necessary to fill the tubes up to the preparation container with the basic liquid on the new prescription,
In such a case, the control device 3 displays a message on the screen of the display device 4, and the reading device 5 reads the bar code of the command code table according to the message to operate the pump 1 by a required discharge amount,
Perform the operation to discard the remaining old chemical solution.

When the tube is filled with the basic liquid on the prescription, the understanding code in the command code table is read. As a result, step 401 of FIG. 4 is started, and the patient designated by the first prescription according to the prescription message displayed on the display device 4 by the data transmitted from the computer 7d on the office C side to the control device 3. The compounding container 10 is connected to the discharge port of the pump 1. Next, in step 402, the mixing container 10 is set on the electronic scale 2.

In step 403, the label reading device 5 reads the print code of the label attached to the blending container 10 on the electronic scale 2. Thereby, the control device 3
It is determined whether or not the compounding container 10 is a container for infusion of the patient instructed by the prescription (step 404).

If the data does not match the infusion container of the designated patient, the operation of the pump 1 is prohibited and step 40
In step 5, confirmation of the mixing container 10 is executed, and the process returns to step 401. If it matches the designated patient's infusion container, the process proceeds to step 406, the electronic balance 2 is automatically reset to zero, and the process proceeds to step 407.

Step 407 is an automatic dispensing execution step, in which the controller 3 first sends a command signal to open only the valve of the suction port to which the chemical solution container of the basic solution is connected according to the prescription based on the prescription information. 1. Based on the measurement signal from the electronic balance, the specific gravity value of the specified type of chemical solution and the theoretical mass value obtained from the prescription amount, and the correction value given in advance, the determination of the remaining amount in step 408 is given. While performing, a predetermined amount of the basic liquid is fed into the blending container 10 from the blending pump device 1 until it is confirmed in step 410 that the prescribed amount of liquid has been fed. In this case, the feeding of the basic liquid is carried out leaving a fixed amount corresponding to the replacement amount in the tube, and this fixed amount is finally replenished in the compounding container 10 after feeding all the prescription drug liquids. Become.

Further, step 408 is a step of monitoring by the control device 3 whether or not the remaining amount of the liquid medicine container 9 connected to the suction port of the pump is larger than the amount of the liquid medicine being fed. If it becomes zero, the control device 3 displays on the screen of the display device 4 that the chemical liquid container has become empty in step 409. Therefore, the chemical liquid container 9 is replenished and replaced according to the flow of FIG. The device 3 returns to step 407 again to continue the liquid feeding, and when the liquid feeding of the prescribed amount is confirmed in step 410, the process proceeds to step 411.

Step 411 is a step for confirming the completion of the preparation of all the medicines in the prescription information by the control device 3, and, for example, calcium solution, amino acid solution, electrolyte solution, and other chemical solution after the basic solution is delivered. , Fat emulsion, etc.
Each drug solution designated by the prescription is sequentially sent to the blending container 10 by repeating from step 407, and if it is determined in step 411 that there is no drug solution to be delivered next, it remains in the tube of the basic solution in step 412. Deliver a fixed amount of basic solution.

Next, in step 413 of FIG. 5, the pump 1 is stopped to terminate the liquid feeding, and in step 414, the weighed value of the preparation container 10 of the electronic balance 2 is taken into the control device 3,
In step 415, the error is calculated. The calculation of this error is
Calculated from the total theoretical mass of the prescribed amount of each drug solution and the specific gravity and the measured weight value of the electronic balance 2, the error = (measured weight value-theoretical mass) / theoretical mass is within an allowable range, for example, ± 3%.
If it exceeds the value, a caution warning is displayed in step 416, and if the error value is within the allowable range, in step 417 the dispensing container 1 is displayed according to the display message of the display device 4.
Remove 0 from the tube to finish dispensing for this prescription.

The next step 418 is a step for determining whether or not the dispensing operation for the next prescription is necessary. If the request for the next dispensing is not communicated to the control device 3, all dispensing operations are performed in step 419. If the request for the next preparation has arrived, it is judged in step 420 whether the basic solution is the same as the basic solution at the previous preparation. If they are the same, the process directly returns to step 401 and the dispensing for the next prescription is performed in the same manner. If the basic liquid is different, the pump 1 is operated according to the flow of FIG. After replacing the inside of the tube with a new basic solution, the process returns to step 401.

In this way, when the dispensing operation for all the prescription dispensing commands sent from the office C side to the control device 3 on the clean room A side is completed, the computer 7d on the office C side records the dispensing data in the prescription data. While adding data, a series of business records are printed out from the printer 7C.

It goes without saying that the above description is only one example of the drug solution preparation using the device according to the present invention, and the present invention can be widely applied to the automatic compound preparation of various drug solutions including infusion solutions and injection solutions.

[0058]

As described above, according to the present invention,
A control device for the compounding pump device and an information processing device for inputting necessary information such as prescription information are separately provided, and an operation control signal for the compounding pump is read from the control device by reading a code table by the reading device. Since it is given, it is possible to perform the control operation required for the blending operation only by operating the reader in the clean room required for the blending operation, and the externally created printed label that becomes a pollution source in the clean room. There is no need to bring in
In addition to weighing data, which is important for the blending operation, is automatically read by a weighing machine such as an electronic scale and objectively evaluated and collated. In addition, verification of connection between each port of the pump and drug supply container and prescription content and actual Since the collation with the content of the formulation is objectively checked, it is possible to avoid human error such as prescription mistakes and input mistakes. Furthermore, the information processing device and the input device are placed outside the clean room to communicate. Since it is also possible to transmit information to the control device in the clean room, especially when connecting by a wireless communication system such as light, wiring work with a special cable is not required, which is ideal for compounding operations of chemical liquids. It is possible to realize a complicated chemical compounding operation by a mechanized operation that does not cause a mistake while maintaining the environment.

[Brief description of drawings]

FIG. 1 is an explanatory diagram showing an outline of a system configuration of a chemical liquid mixing device according to a preferred embodiment of the present invention.

FIG. 2 is a flowchart showing an example of a prescription information registration operation.

FIG. 3 is a flowchart showing an example of a connecting operation between a medicine package container and each suction port of a pump.

FIG. 4 is a flowchart illustrating the first half of a dispensing operation.

FIG. 5 is a flowchart illustrating the second half of the dispensing operation.

[Explanation of symbols]

 1: Preparation pump device 2: Electronic scale (weighing device) 3: Control device 4: Display device 5: Reading device 6: Label printer 7a: Keyboard (input device) 7b: Display device (output device) 7c: Printer device 7d: Computer (information processing device, storage device) 8a: communication coupler 8b: communication coupler A: clean room C: office

Claims (7)

[Claims] 1. When the operation control signal and the command signal are received, the chemical liquid is selectively sucked from a plurality of suction ports which receive the supply of the chemical liquid of a predetermined type according to the opening / closing operation of the valve by the command signal. A blending pump device for feeding the blending container to the blending container, a weighing machine for weighing the blending container and outputting an electric measurement signal indicating the weight of the chemical liquid fed from the blending pump into the blending container, and each of the suction ports. An input device for inputting drug information, patient information, prescription information, and operation signal of each drug solution to be supplied, a drug solution of a type according to the prescription and its prescription amount based on the above information in response to the input of the operation signal, and An information processing device that specifies the corresponding suction port and generates pump operation control information corresponding to the specified contents, each information input from the input device, and the information processing device. A storage device for storing the pump operation control information specified and generated by the output device, an output device for displaying the processing content of the information processing device, and at least a part of the information and the pump operation control information from the information processing device. While giving the command signal to the compounding pump device so as to open only the valve of the suction port corresponding to each type of chemical liquid according to the prescription, the measurement signal from the scale and the specific gravity value of the chemical liquid of the designated type and Based on the theoretical mass value obtained from the prescription amount and a control device for instructing the amount of the chemical liquid to be sent from the blending pump device to the blending container, and an operation control signal of the blending pump device via a controller by reading a code table. A chemical liquid blending device, comprising: a reading device for feeding the blending pump. 2. The patient information includes administration contraindicated drug information, and the information processing device displays a warning on the output device based on the administration contraindication drug information and the drug information and / or prescription information. The chemical liquid preparation device according to claim 1. 3. The drug information includes unusable information that represents a combination of drugs that is inconvenient for treatment or mixing, and the information processing device warns the output device based on the unusable information and prescription information. It displays, The chemical | medical solution preparation apparatus of Claim 1 characterized by the above-mentioned. 4. The liquid medicine blending device according to claim 1, wherein a label printer that prints a label to be attached to a blending container corresponding to the prescription information is attached to the control device. 5. The control device prohibits the operation of the blending pump when the reading result of the label attached to the blending container before the blending by the reading device does not match the prescription information. The chemical | medical solution preparation apparatus of Claim 4. 6. A computer in which the blending pump device, the weighing device, the control device, and the reading device are installed in a clean room, and the input device, the information processing device, the storage device, and the output device are installed outside the clean room. The drug solution mixing device according to claim 1, wherein the drug solution mixing device is configured by a system, and the information processing device and the control device are connected by a communication unit. 7. The chemical liquid preparation device according to claim 6, wherein the communication unit includes a wireless communication system.