JPH09201334A - Ophthalmological device - Google Patents

Ophthalmological device

Info

Publication number
JPH09201334A
JPH09201334A JP8013409A JP1340996A JPH09201334A JP H09201334 A JPH09201334 A JP H09201334A JP 8013409 A JP8013409 A JP 8013409A JP 1340996 A JP1340996 A JP 1340996A JP H09201334 A JPH09201334 A JP H09201334A
Authority
JP
Japan
Prior art keywords
interference pattern
surface layer
hue
eye
image
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP8013409A
Other languages
Japanese (ja)
Other versions
JP3556033B2 (en
Inventor
Takayoshi Suzuki
孝佳 鈴木
Misao Makino
美佐雄 牧野
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kowa Co Ltd
Original Assignee
Kowa Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kowa Co Ltd filed Critical Kowa Co Ltd
Priority to JP01340996A priority Critical patent/JP3556033B2/en
Publication of JPH09201334A publication Critical patent/JPH09201334A/en
Application granted granted Critical
Publication of JP3556033B2 publication Critical patent/JP3556033B2/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B3/00Apparatus for testing the eyes; Instruments for examining the eyes
    • A61B3/10Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
    • A61B3/101Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions for examining the tear film

Abstract

PROBLEM TO BE SOLVED: To provide an ophthalmological device in which conditions of a lacrimal liquid surface layer of a subject eye can be objectively evaluated. SOLUTION: An image of interference patterns formed in a lacrimal liquid surface layer is picked up by a CCD camera 7, and diagnosis of a subject eye is made based on the interference patterns. In the image of the interference patterns, plural areas are set by an area setting means 13, and a color phase of each area is operated by a color phase operating device 9. Evaluation of the lacrimal liquid surface layer is performed by a grade determining circuit 10 based on the operated color phase. In this constitution, grading which conventionally has been made by a diagnoser can be performed by image processing, thereby subjectivity is not included in diagnosis, but reliability can be improved.

Description

【発明の詳細な説明】Detailed Description of the Invention

【0001】[0001]

【発明の属する技術分野】本発明は、眼科装置に関し、
特に被検眼の涙液表層を観察することにより、ドライア
イを診断することのできる眼科装置に関するものであ
る。
TECHNICAL FIELD The present invention relates to an ophthalmologic apparatus,
In particular, the present invention relates to an ophthalmologic apparatus capable of diagnosing dry eye by observing the surface layer of tear fluid of an eye to be examined.

【0002】[0002]

【従来の技術】近年、VDT(visual display termina
l)作業者の増加や冷暖房による部屋の乾燥などにより
ドライアイ患者が増加している。ドライアイになると角
膜上皮障害や結膜障害、その他にも種々の眼科疾患を併
発するおそれがあり、ドライアイの診断は眼科診断の上
で重要なテーマとなっている。
2. Description of the Related Art In recent years, VDT (visual display termina)
l) The number of dry eye patients is increasing due to the increase of workers and the drying of rooms by air conditioning. When dry eye occurs, corneal epithelial disorder, conjunctival disorder, and various other ophthalmic diseases may occur at the same time. Diagnosis of dry eye is an important theme in ophthalmic diagnosis.

【0003】従来は、生体染色検査(ローズベンガル
法、フルオレセイン法)、涙液量検査(シルマーテス
ト、綿糸法、BUT、クリアランステスト)などにより
ドライアイの診断を行なっていたが、薬物点眼や異物接
触を伴うため被検者の苦痛は避けられなかった。そこ
で、特開昭62−222143号、特開平7−1361
20号、特願平6−189734号等に記載されたよう
に、被検眼に光を照射して涙液層での干渉縞を観察する
方法が試みられている。これら装置では、被検眼の涙液
表層で形成される干渉模様(虹色に変化するカラーの干
渉模様)のカラー画像が受光光学系の光電変換素子によ
り光電変換され、その干渉模様のカラー画像が表示手段
に表示されるので、診断者はこの干渉模様を観察するこ
とにより涙液表層の状態を知り、ドライアイの簡易的診
断を行なうことができる。
Conventionally, the diagnosis of dry eye has been performed by a vital stain test (Rose Bengal method, fluorescein method), a tear volume test (Schirmer test, cotton thread method, BUT, clearance test), etc. The suffering of the subject was unavoidable because of the contact. Then, JP-A-62-222143 and JP-A-7-1361
No. 20, Japanese Patent Application No. 6-189734, etc., a method of irradiating the eye to be examined with light to observe interference fringes in the tear film has been attempted. In these devices, a color image of an interference pattern (interference pattern of a color that changes to a rainbow color) formed on the surface of the tear fluid of the eye to be examined is photoelectrically converted by the photoelectric conversion element of the light receiving optical system, and a color image of the interference pattern is obtained. Since the information is displayed on the display means, the diagnosing person can know the state of the surface layer of the tear fluid by observing the interference pattern, and can make a simple diagnosis of dry eye.

【0004】[0004]

【発明が解決しようとする課題】しかし、従来の装置で
は、そのための診断には、画面の色模様を診断者が直接
見て、ドライアイのグレードを評価しており、診断者の
主観に頼るため、グレード分けも見る人によって異なる
という問題があった。
However, in the conventional apparatus, the diagnosis for that purpose is made by the diagnostician directly looking at the color pattern on the screen to evaluate the grade of the dry eye and depends on the subjectivity of the diagnostician. Therefore, there was a problem that grade classification also differs depending on the viewer.

【0005】本発明は、このような問題点を解決するた
めになされたもので、被検眼の涙液表層の状態を客観的
に評価できる眼科装置を提供することをその課題とす
る。
The present invention has been made to solve the above problems, and an object thereof is to provide an ophthalmologic apparatus capable of objectively evaluating the state of the surface layer of the tear fluid of the eye to be examined.

【0006】[0006]

【課題を解決するための手段】本発明は、この課題を解
決するために、被検眼の涙液表層で形成される干渉模様
を撮像し、その干渉模様に基づいて被検眼を診断する眼
科装置において、前記干渉模様の撮影像に複数個のエリ
アを設定する手段と、前記各エリアの色相を演算する手
段と、前記演算された色相に基づいて涙液表層を評価す
る手段とを設ける構成を採用した。
In order to solve this problem, the present invention takes an interference pattern formed on the surface layer of the tear fluid of the eye to be examined, and diagnoses the eye to be examined based on the interference pattern. In the configuration, a configuration is provided in which a means for setting a plurality of areas in the captured image of the interference pattern, a means for calculating the hue of each area, and a means for evaluating the tear surface layer based on the calculated hue are provided. Adopted.

【0007】このような構成では、従来診断者が行って
いたグレード分けを画像処理によって行うことができる
ため、診断に主観が入らず、信頼性が高くなる。
With such a configuration, since the grade classification conventionally performed by a diagnostician can be performed by image processing, subjectivity is not included in the diagnosis and reliability is improved.

【0008】[0008]

【発明の実施の形態】以下、図を参照して本発明の実施
形態を説明する。
DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS An embodiment of the present invention will be described below with reference to the drawings.

【0009】図1は、本発明に係わる眼科装置の概略構
成を示し、同図において、符号1で図示するものは、被
検眼Eを照明するための白色光源でハロゲンランプ等に
よって構成される。白色光源1から射出された光は、照
明視野を制限するマスク2を通過後、レンズ3、ハーフ
ミラー4、レンズ5を介して被検眼E上の所定点Pを照
明する。点Pの位置は被検眼Eの角膜上の涙液最表層の
脂質層に選択される。なお、白色光源1は調光回路(不
図示)により光量が調節できるようになっている。
FIG. 1 shows a schematic configuration of an ophthalmologic apparatus according to the present invention. In FIG. 1, a reference numeral 1 is a white light source for illuminating an eye E to be inspected and is constituted by a halogen lamp or the like. The light emitted from the white light source 1 passes through the mask 2 that limits the illumination visual field, and then illuminates a predetermined point P on the eye E through the lens 3, the half mirror 4, and the lens 5. The position of the point P is selected as the outermost lipid layer of the tear fluid on the cornea of the eye E to be examined. The light amount of the white light source 1 can be adjusted by a light control circuit (not shown).

【0010】点Pからの反射光(涙液最表層の脂質層の
表面及び裏面での反射光)は脂質層の厚みその他の状態
により種々の干渉模様を形成する。この干渉模様を形成
する反射光はレンズ5、ハーフミラー4、レンズ6を介
してカラーCCDカメラ7に受光され、干渉模様のカラ
ー画像がCCDカメラ7により光電変換され、そのRG
Bビデオ信号がビデオ記憶装置8に記憶される。この記
憶された干渉模様の像は、モニタ12で表示されるとと
もに、RGBビデオ信号情報に基づき各エリア内の色相
を演算する色相演算装置9に入力される。この色相演算
装置9は、グレード判別回路10に接続されており、干
渉模様の色相に基づいてドライアイのグレードが判別さ
れる。その結果は出力表示回路11において表示され、
またモニタ12にも表示される。また、ビデオ記憶装置
8には、エリア(ポイント)設定装置13が接続されて
おり、干渉模様の画面領域を複数のエリアに分割するこ
とができる。
Reflected light from point P (reflected light on the front and back surfaces of the outermost lipid layer of the tear fluid) forms various interference patterns depending on the thickness of the lipid layer and other conditions. The reflected light forming the interference pattern is received by the color CCD camera 7 via the lens 5, the half mirror 4, and the lens 6, and the color image of the interference pattern is photoelectrically converted by the CCD camera 7, and its RG
The B video signal is stored in the video storage device 8. The stored interference pattern image is displayed on the monitor 12 and is also input to the hue calculation device 9 that calculates the hue in each area based on the RGB video signal information. The hue calculation device 9 is connected to the grade determination circuit 10 and determines the dry eye grade based on the hue of the interference pattern. The result is displayed on the output display circuit 11,
It is also displayed on the monitor 12. Further, an area (point) setting device 13 is connected to the video storage device 8, and the screen area of the interference pattern can be divided into a plurality of areas.

【0011】このような構成において、白色光源1が点
灯され、マスク2、レンズ3、ハーフミラー4、レンズ
5を介して光源からの光が被検眼角膜上の涙液層の最表
層である脂質層に投光される。その表面と裏面からの反
射光がレンズ6を介してカラーCCDカメラ7のCCD
受光面に受光され、干渉模様のカラー像が受像される。
このような干渉模様が図2に図示されており、例えば、
(A)は健常者の干渉模様を、(B)はドライアイの患
者の干渉模様を示している。
In such a structure, the white light source 1 is turned on, and the light from the light source through the mask 2, the lens 3, the half mirror 4, and the lens 5 is the outermost layer of the tear film on the cornea of the eye to be examined. It is projected on the layer. The reflected light from the front surface and the back surface passes through the lens 6 and the CCD of the color CCD camera 7
The light is received by the light receiving surface, and a color image having an interference pattern is received.
Such an interference pattern is shown in FIG.
(A) shows an interference pattern of a healthy person, and (B) shows an interference pattern of a dry eye patient.

【0012】色相演算装置8は、RGBビデオ信号情報
に基づきエリア設定装置13により設定された各エリア
内の色相を演算する。すなわち、各ポイントが設定され
ると、そのポイントに対応する画像がビデオ記憶装置8
から読み出され、色相演算装置8は、そのポイントでの
画像の色相を以下の演算によって求める。
The hue calculator 8 calculates the hue in each area set by the area setting device 13 based on the RGB video signal information. That is, when each point is set, the image corresponding to the point is stored in the video storage device 8.
The hue calculation device 8 obtains the hue of the image at that point by the following calculation.

【0013】R=IR/(IR+IG+IB) G=IG/(IR+IG+IB) B=IB/(IR+IG+IB) ここで、R,G,Bはそれぞれ赤色の色相、緑色の色
相、青色の色相を意味し、IR、IG、IBはそれぞれ
Rビデオ信号電圧、Gビデオ信号電圧、Bビデオ信号電
圧を意味する。
R = IR / (IR + IG + IB) G = IG / (IR + IG + IB) B = IB / (IR + IG + IB) where R, G and B mean red hue, green hue and blue hue, respectively, and IR , IG and IB mean R video signal voltage, G video signal voltage and B video signal voltage, respectively.

【0014】上記ポイントの画面上の配置は、例えば図
3に示すようになっている。ここでは、所定ポイントの
大きさは1画素分としたが、例えば10画素を1ブロッ
クとしてR,G,Bの演算を行ってもよい。またここで
は、ポイント数は12個としたが、このポイント数は多
いほど良好な結果が得られる。
The arrangement of the points on the screen is as shown in FIG. 3, for example. Here, the size of the predetermined point is one pixel, but the calculation of R, G, B may be performed, for example, with 10 pixels as one block. Although the number of points is 12 here, the larger the number of points, the better the result.

【0015】色相演算装置により演算された各色相R、
G、Bの数値結果が図4に示されている。この表から、
ポイント6、10の2ヶ所で赤成分(R)が強く出てお
り、この部分では干渉模様が赤色であることが、また他
のポイントではR、G、Bのレベル値に差が大きく出て
いないので、白色に近い干渉模様であることが理解でき
る。
Each hue R calculated by the hue calculation device,
The numerical results of G and B are shown in FIG. From this table,
The red component (R) is strong at two points 6 and 10, and the interference pattern is red at this part. At other points, there is a large difference in the R, G, and B level values. Since there is no interference pattern, it can be understood that the interference pattern is close to white.

【0016】このような演算結果に基づいてグレード判
別回路10において、以下のような判別が行なわれる。
The grade determination circuit 10 makes the following determination based on the result of such calculation.

【0017】全てのポイントでR,G,Bが0.3以上
のとき……グレード1 2つ以上の複数ポイントで、Rが0.5以上を示し、尚
且つ別の全てのポイントではR,G,Bが5未満である
とき……グレード2 2つ以上の複数ポイントで、Rが0.5以上を示し、尚
且つ別の2つ以上の複数ポイントで、Bが0.5以上を
示したとき……グレード3 このグレード分けの例にしたがって、上記の結果を判別
すると、2つ以上のポイントでRが0.7を示してお
り、グレード2に相当している。
When R, G and B are 0.3 or more at all points ... Grade 1 R is 0.5 or more at two or more points, and at all other points R, G and B When G and B are less than 5 ... Grade 2 R is 0.5 or more with two or more points, and B is 0.5 or more with another two or more points. When ... grade 3 When the above result is discriminated according to this grade classification example, R shows 0.7 at two or more points, which corresponds to grade 2.

【0018】このグレード分けはあくまで例に過ぎな
い。R,G,Bの組み合わせを多く行えば、グレード数
はさらに増やすことが可能になる。また、このようなグ
レード分けにより被検眼のドライアイの評価付けを行な
うことが可能になる。
This grading is merely an example. The number of grades can be further increased by increasing the number of combinations of R, G, and B. Further, such grade classification makes it possible to evaluate the dry eye of the subject's eye.

【0019】このようなグレードの判別結果は、出力表
示装置11に表示され、またモニタ12に表示される。
The result of grade discrimination is displayed on the output display device 11 and also on the monitor 12.

【0020】[0020]

【発明の効果】以上説明したように、本発明では、被検
眼の涙液表層で形成される干渉模様の撮影像に複数個の
エリアを設定し、各エリアの演算された色相に基づいて
涙液表層を評価するようにしているので、従来診断者が
行っていたグレード分けを画像処理によって行うことが
できるため、診断に主観が入らず、信頼性が高くなる、
という優れた効果が得られる。
As described above, according to the present invention, a plurality of areas are set in the photographed image of the interference pattern formed on the tear liquid surface layer of the eye to be inspected, and tears are calculated based on the calculated hue of each area. Since the liquid surface layer is evaluated, it is possible to perform grade classification, which was conventionally performed by a diagnostician, by image processing.
An excellent effect is obtained.

【図面の簡単な説明】[Brief description of drawings]

【図1】本発明の眼科装置の全体構成を示す概略構成図
である。
FIG. 1 is a schematic configuration diagram showing an overall configuration of an ophthalmologic apparatus of the present invention.

【図2】図1の眼科装置で観察される干渉模様の像を示
した説明図である。
FIG. 2 is an explanatory diagram showing an image of an interference pattern observed with the ophthalmologic apparatus of FIG.

【図3】設定されたポイントを示す説明図である。FIG. 3 is an explanatory diagram showing set points.

【図4】各ポイントでの色相値を示す表図である。FIG. 4 is a table showing hue values at each point.

【符号の説明】[Explanation of symbols]

1 白色光源 7 CCDカメラ 8 ビデオ記憶装置 9 色相演算装置 10 グレード判別回路 11 出力表示装置 12 モニタ 13 エリア設定装置 1 White Light Source 7 CCD Camera 8 Video Storage Device 9 Hue Calculator 10 Grade Discrimination Circuit 11 Output Display Device 12 Monitor 13 Area Setting Device

Claims (1)

【特許請求の範囲】[Claims] 【請求項1】 被検眼の涙液表層で形成される干渉模様
を撮像し、その干渉模様に基づいて被検眼を診断する眼
科装置において、 前記干渉模様の撮影像に複数個のエリアを設定する手段
と、 前記各エリアの色相を演算する手段と、 前記演算された色相に基づいて涙液表層を評価する手段
と、 を設けたことを特徴とする眼科装置。
1. An ophthalmologic apparatus which images an interference pattern formed on a tear liquid surface layer of an eye to be inspected and diagnoses the eye to be inspected based on the interference pattern, wherein a plurality of areas are set in a captured image of the interference pattern. An ophthalmologic apparatus comprising: a unit, a unit that calculates a hue of each area, and a unit that evaluates a tear surface layer based on the calculated hue.
JP01340996A 1996-01-30 1996-01-30 Ophthalmic equipment Expired - Lifetime JP3556033B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP01340996A JP3556033B2 (en) 1996-01-30 1996-01-30 Ophthalmic equipment

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP01340996A JP3556033B2 (en) 1996-01-30 1996-01-30 Ophthalmic equipment

Publications (2)

Publication Number Publication Date
JPH09201334A true JPH09201334A (en) 1997-08-05
JP3556033B2 JP3556033B2 (en) 2004-08-18

Family

ID=11832343

Family Applications (1)

Application Number Title Priority Date Filing Date
JP01340996A Expired - Lifetime JP3556033B2 (en) 1996-01-30 1996-01-30 Ophthalmic equipment

Country Status (1)

Country Link
JP (1) JP3556033B2 (en)

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US9339177B2 (en) 2012-12-21 2016-05-17 Tearscience, Inc. Full-eye illumination ocular surface imaging of an ocular tear film for determining tear film thickness and/or providing ocular topography
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