JP7019160B2 - Chemical injection device and injection needle used for the device - Google Patents

Description

The present invention relates to a drug solution injecting device for injecting a drug solution into a patient and an injection needle used in the device.

Conventionally, as a method of detachably connecting a syringe and an injection needle, a tapered convex portion provided at the tip of the syringe and a tapered concave portion provided at the hub of the injection needle are frictionally engaged with the syringe. A method of detachably connecting the injection needle to and from the injection needle (luer lock type) is known (see, for example, Patent Document 1). This method is useful in that it can achieve excellent sealing between the syringe and the needle, but in order to achieve such sealing, a tapered protrusion provided at the tip of the syringe. Since the diameter of the portion needs to be slightly larger than the diameter of the tapered concave portion provided on the hub of the injection needle, a space is inevitably created between the tapered convex portion and the tapered concave portion. Become. It has been known that the chemical solution injection device cannot inject the chemical solution in this space, so that this space becomes a dead space. When injecting expensive chemicals such as biotechnology drugs, the cost of the chemicals lost by this dead space cannot be ignored. Therefore, when injecting an expensive chemical solution, the above-mentioned conventional tapered convex portion provided at the tip of the syringe and the tapered concave portion provided at the hub of the injection needle are frictionally engaged with each other. By not adopting a method (luer lock type) in which the syringe and the injection needle are detachably connected to each other, a measure for avoiding the above-mentioned problem itself has been taken exclusively (for example, Patent Document 1). reference).

Japanese Patent No. 4328064

The present invention has been made to solve the above-mentioned problems by an approach different from the conventional one, and to inject the drug solution without wasting the drug solution even when a space is created between the syringe and the injection needle. It is an object of the invention to provide a drug infusion device that enables and an injection needle used in the device.

The syringe of the present invention is a syringe needle detachably attached to the tip of the syringe, and the syringe and the syringe needle are the syringe when the syringe needle is attached to the tip of the syringe. It is configured to create a space between the syringe and the syringe needle, which comprises a hub for receiving the tip of the syringe and at least one needle protruding from the tip of the hub. Each of the at least one needle has a hollow portion, the filler has at least one through hole, and the filler comprises a filler for filling at least a part of the space. When the syringe needle is attached to the tip of the syringe, the drug solution filled in the chamber of the syringe passes through the at least one through hole of the filler and of the at least one needle. It is configured to flow into each of the hollow portions.

In one embodiment of the invention, the tip of the syringe is provided with a tapered ridge, and the hub is frictionally engaged with the tapered ridge provided at the tip of the syringe. It has a matching tapered recess, and the space is configured to be created by frictional engagement between the tapered protrusion and the tapered recess.

In one embodiment of the invention, the filler may comprise a compressible and deformable material.

In one embodiment of the invention, the material may be silicone rubber.

In one embodiment of the invention, the filler is configured to compress and deform in the space.

In one embodiment of the invention, the tapered recess may have at least one fitting ridge that mates with the at least one through hole in the filler.

In one embodiment of the present invention, the tip of the syringe is provided with a drug solution outlet that leads the drug solution to be filled in the chamber to the syringe, and at least one through hole of the filler. The inner diameter of each of the above is larger than the inner diameter of each hollow portion of the at least one needle and smaller than the inner diameter of the chemical liquid outlet portion.

The drug solution injection device of the present invention is a drug solution injection device for injecting a drug solution, and the drug solution injection device includes a syringe and an injection needle detachably attached to the tip of the syringe, and the syringe is the syringe. The injection needle fills at least a portion of the space, including a hub for receiving the tip of the syringe, at least one needle protruding from the tip of the hub, and a chamber filled with the drug solution. Each of the at least one needle has a hollow portion, the filler has at least one through hole, and the filler has the injection needle of the syringe. When attached to the tip, the drug solution filled in the chamber of the syringe passes through the at least one through hole in the filler into the hollow portion of each of the at least one needle. It is configured to flow.

INDUSTRIAL APPLICABILITY According to the present invention, there is provided a drug solution injection device capable of injecting a drug solution without wasting the drug solution even when a space is created between the syringe and the injection needle, and an injection needle used for the device. It is possible.

Disassembled vertical sectional view of the chemical solution injection device 100 in a state where the chemical solution injection device 100 of one embodiment of the present invention is disassembled. Longitudinal sectional view of the engaging portion between the syringe 10 and the injection needle 30 in a state where the injection needle 30 is attached to the tip of the syringe 10. Longitudinal sectional view of the injection needle 30 according to one embodiment of the present invention. Longitudinal sectional view of the injection needle 30 according to one embodiment of the present invention.

Hereinafter, embodiments of the present invention will be described with reference to the drawings.

FIG. 1 is an exploded vertical sectional view of the chemical solution injection device 100 in a state where the chemical solution injection device 100 according to one embodiment of the present invention is disassembled.

The drug solution injection device 100 includes a syringe 10 and an injection needle 30 that is detachably attached to the tip of the syringe 10.

The syringe 10 includes a syringe 12 having a chamber 13 filled with a drug solution and a plunger 20 inserted into the chamber 13 of the syringe 12.

The tip of the syringe 12 (that is, the tip of the syringe 10) is provided with a tapered protrusion 11.

The tip end portion of the chamber 13 communicates with a chemical liquid outlet portion 14 formed in the tapered convex portion 11. An opening 15 is provided at the rear end of the chamber 13.

The plunger 20 is configured to be able to be inserted into the chamber 13 via the opening 15. The plunger 20 is movable along the longitudinal axis of the syringe 12. A piston 21 is joined to the plunger 20. By moving the plunger 20 along the longitudinal axis of the syringe 12, the piston 21 also moves along the longitudinal axis of the syringe 12.

An operation unit 22 is provided at the rear end of the plunger 20. By pulling the operation unit 22, it is possible to perform an operation of pulling the plunger 20 with respect to the syringe 12. By pushing the operation unit 22, it is possible to perform an operation of pushing the plunger 20 with respect to the syringe 12.

A protrusion 23 is provided at the tip of the plunger 20. When the plunger 20 moves to the tip of the chamber 13, the protrusion 23 functions to shield the space of the chemical liquid outlet portion 14 formed in the tapered convex portion 11. This makes it possible to significantly reduce the amount of the drug solution that remains in the space of the drug solution lead-out unit 14 without being supplied to the injection needle 30 (see FIG. 2).

The chemical liquid lead-out unit 14 is, for example, a circular hole. In this case, the chemical liquid lead-out unit 14 may have an arbitrary inner diameter. In one embodiment, the inner diameter of the chemical solution lead-out unit 14 is about 1.5 to about 2.5 mm, but the present invention is not limited thereto. However, the chemical liquid lead-out unit 14 is not limited to the circular hole. The chemical liquid lead-out unit 14 may be a hole having an arbitrary shape other than the circular hole. For example, the chemical liquid lead-out unit 14 may be a triangular hole, a polygonal hole having a quadrangle or more, or an elliptical hole.

FIG. 2 is a vertical cross-sectional view of an engaging portion between the syringe 10 and the injection needle 30 in a state where the injection needle 30 is attached to the tip of the syringe 10.

The injection needle 30 includes a hub 31 and a needle 33 protruding from the tip of the hub 31. The hub 31 has a tapered recess 32. The tapered concave portion 32 is configured to frictionally engage with the tapered convex portion 11 provided at the tip end portion of the syringe 12. Here, in order to realize a high sealing property between the syringe 10 and the injection needle 30 in order to prevent the drug solution from leaking to the outside, the tapered convex portion 11 provided at the tip of the syringe 12 It is necessary to make the size (for example, the outer diameter of the convex portion 11) equal to or slightly larger than the size of the tapered concave portion 32 provided in the hub 31 of the injection needle 30 (for example, the inner diameter of the concave portion 32). There is. Therefore, a space is inevitably generated between the tapered convex portion 11 and the tapered concave portion 32. Since the chemical solution injection device 100 cannot inject the chemical solution in this space, this space is a dead space. The injection needle 30 is at least a part of this dead space (that is, a space created between the tapered convex portion 11 and the tapered concave portion 32 when the injection needle 30 is attached to the tip of the syringe 10). Further includes a filler 40 for filling.

The shape of the tapered recess 32 can be any shape as long as it can be frictionally engaged with the tapered protrusion 11 provided at the tip of the syringe 10. In one embodiment, the shape of the tapered recess 32 is preferably a substantially conical shape from the viewpoint of manufacturing cost, engagement accuracy, and the like, but the present invention is not limited thereto. For example, the shape of the tapered recess 32 may be a triangular pyramid or a quadrangular pyramid. In one embodiment, the inner diameter of the tapered recess 32 is about 3-4 mm at the tip, but the present invention is not limited thereto.

In the embodiment shown in FIGS. 1 and 2, a tapered convex portion 11 (for example, a luer lock type convex portion) is provided at the tip of the syringe 12, and the hub 31 of the injection needle 30 is provided. Although an example in which the tapered recess 32 (for example, a luer lock type recess) is provided in the above is described, the present invention is not limited to this. When the injection needle 30 is attached to the tip of the syringe 10, the convex portion 11 and the concave portion 32 can have any shape as long as a space is created between the convex portion 11 and the concave portion 32. For example, the convex portion 11 may be a male screw-shaped convex portion (for example, a lure tip type convex portion), or the concave portion 32 may be a female screw-shaped concave portion (for example, a lure tip type concave portion). good. As long as the filling 40 for filling at least a part of the space (dead space) generated between the convex portion 11 provided at the tip of the syringe 12 and the concave portion 32 provided at the hub 31 of the injection needle 30 is included. The injection needle 30 containing such a filler 40 is within the scope of the present invention, and the drug solution injection device 100 including such an injection needle 30 is within the scope of the present invention.

The material of the filler 40 can be any material. In one embodiment, the material of the filler 40 is preferably a material that is compressively deformable. For example, the compressionally deformable material is selected from the group consisting of silicon rubber, fluororubber, nitrile rubber, butyl rubber, urethane rubber, fluororubber, natural rubber, elastomer, and elastomer material. By constructing at least a part of the filler 40 with a material that can be compressed and deformed, it is generated between the convex portion 11 and the concave portion 32 when the convex portion 11 of the syringe 10 and the concave portion 32 of the hub 31 are engaged with each other. Even if there is a difference in the size of the space (dead space), the dead space can be suitably filled by the compression deformation of the filling material 40. This makes it possible to reduce the amount of the chemical solution that remains in the dead space without being supplied to the needle 33. In other embodiments, the material of the filler 40 may be plastic, metal, or the like that is not compressionally deformed.

The shape and size of the filler 40 are at least a part of the space (dead space) created between the convex portion 11 and the concave portion 32 when the convex portion 11 of the syringe 10 and the concave portion 32 of the hub 31 are engaged with each other. Can be of any shape and size as long as it can be filled. In one embodiment, as shown in FIG. 2, the filler 40 is a cylinder having a size that almost completely fills the space (dead space) generated between the convex portion 11 and the concave portion 32. However, the present invention is not limited thereto. For example, the shape of the filler 40 may be a triangular cylinder or a polygonal cylinder such as a square cylinder. Further, the size of the filling 40 may be smaller than the size of the dead space. In one embodiment, the shape and size of the filler 40 is, for example, a cylinder having an outer diameter of about 3-5 mm and a height of about 3-5 mm.

The filler 40 has a through hole 41. The through hole 41 is configured to allow the drug solution lead-out portion 14 of the syringe 10 and the hollow portion of the needle 33 to communicate with each other. Thereby, the chemical solution filled in the chamber 13 of the syringe 10 can be supplied to the hollow portion of the needle 33 through the chemical solution outlet portion 14 of the syringe 10 and the through hole 41 of the filler 40. The drug solution supplied to the hollow portion of the needle 33 is injected into the patient's body.

In the embodiment shown in FIGS. 1 and 2, an example in which the number of needles 33 is one and the number of through holes 41 of the filler 40 is one has been described, but the present invention is limited thereto. Not done. The number of needles 33 can be any number. The number of through holes 41 can also be any number. For example, as shown in FIG. 3, three through holes 41 (the same number as the number of needles 33) may be provided for the three needles 33. Alternatively, as shown in FIG. 4, one through hole 41 (less than the number of needles 33) may be provided for each of the three needles 33.

The size (for example, inner diameter) of the through hole 41 can be any size (for example, inner diameter) as long as the drug solution outlet portion 14 of the syringe 10 and the hollow portion of the needle 33 can be communicated with each other. In one embodiment, the inner diameter of the through hole 41 is preferably larger than the inner diameter of the hollow portion of the needle 33 and smaller than the inner diameter of the chemical liquid outlet portion 14. As a result, the chemical solution can smoothly flow from the chamber 13 of the syringe 10 to the hollow portion of the needle 33, and the amount of the chemical solution that remains in the dead space without being supplied to the hollow portion of the needle 33 can be reduced. Is. However, the present invention is not limited to this. For example, the inner diameter of the through hole 41 may be the same as the inner diameter of the hollow portion of the needle 33, or may be the same as or larger than the inner diameter of the chemical liquid outlet portion 14. In one embodiment, the inner diameter of the through hole 41 is, for example, about 0.1 to about 2.5 mm.

In one embodiment, the through hole 41 may be a circular hole, but the present invention is not limited thereto. The through hole 41 may be a hole having any shape other than the circular hole. For example, the through hole 41 may be a triangular hole, a polygonal hole having a quadrangle or more, or an elliptical hole.

The filler 40 is fixed in the recess 32 of the hub 31 by a fixing member such as an adhesive in such a manner that the through hole 41 communicates the chemical liquid lead-out portion 14 and the hollow portion of the needle 33. The method of fixing the filler 40 in the recess 32 of the hub 31 is not limited to adhesion. Other methods such as fusion and press fitting may be used to secure the filler 40 into the recess 32 of the hub 31. Further, as shown in FIG. 2, a fitting convex portion 34 that fits with the through hole 41 of the filler 40 may be provided in the concave portion 32. By fitting the through hole 41 of the filling 40 and the fitting convex portion 34, the filling 40 can be firmly fixed to the engaging recess 32. In the embodiment shown in FIG. 2, the number of fitting protrusions 34 is one, but the present invention is not limited thereto. The number of fitting protrusions 34 can be any one or more. For example, the number of fitting protrusions 34 may be any number depending on the number of through holes 41.

The hub 31 is provided with at least one through hole 35 for passing at least one needle 33. The through hole 35 is connected to a recess 32 formed inside the hub 31. In the embodiment shown in FIG. 2, the number of through holes 35 is one (the same number as the number of needles 33), but the present invention is not limited thereto. The number of needles 33 and the number of through holes 35 can be arbitrary. For example, when the number of needles 33 is three, three through holes 35 (the same number as the number of needles 33) may be provided, or when the number of needles 33 is five. , Five through holes 35 (the same number as the number of needles 33) may be provided. The needle 33 is fixed in the through hole 35 by a fixing member such as an adhesive in a state where the tip thereof protrudes from the tip of the hub 31 while being inserted into the through hole 35. The method of fixing the needle 33 in the through hole 35 is not limited to adhesion. Other methods such as fusion may be used to secure the needle 33 into the through hole 35.

The material of the needle 33 can be any material. In one embodiment, the material of the needle 33 is preferably stainless steel, aluminum, or an aluminum alloy from the viewpoint of manufacturing cost, strength, and the like, but the present invention is not limited thereto. For example, the material of the needle 33 may be a metal material such as titanium or a titanium alloy, a plastic material, or the like.

The material of the hub 31 can be any material. In one embodiment, the material of the hub 31 is preferably a thermoplastic resin such as polycarbonate, polypropylene, or ABS resin from the viewpoint of manufacturing cost and the like, but the present invention is not limited thereto. For example, the material of the hub 31 may be a metal material such as stainless steel. When a thermoplastic resin is used as the material of the hub 31, the hub 31 can be manufactured by injection molding or the like. Further, the metal needle 33 and the hub 31 made of a thermoplastic resin may be integrally molded by injection molding or the like.

The size of the hollow portion of the needle 33 (for example, the inner diameter) can be any size (for example, the inner diameter) based on the type of the chemical solution used and the conditions to which the chemical solution is administered. In one embodiment, the inner diameter of the hollow portion of the needle 33 is preferably 0.1 to 0.6 mm, but the present invention is not limited thereto. For example, the inner diameter of the hollow portion of the needle 33 may be 0.1 mm or may be 0.6 mm or more.

In one embodiment, the hollow portion of the needle 33 may be a circular hole, but the present invention is not limited thereto. The hollow portion of the needle 33 may be a hole having an arbitrary shape other than the circular hole. For example, the hollow portion of the needle 33 may be a triangular hole, a polygonal hole having a quadrangle or more, or an elliptical hole.

The chemical injection device 100 may include a cap (not shown) that protects the needle 33.

Next, a method of using the chemical injection device 100 will be described.

The syringe 10 and the injection needle 30 are engaged by frictionally engaging the convex portion 11 provided at the tip end portion of the syringe 10 and the concave portion 32 provided at the hub 31 of the injection needle 30. This completes the assembly of the chemical injection device 100.

When the convex portion 11 and the concave portion 32 are engaged, the space (dead space) generated between the convex portion 11 and the concave portion 32 is filled by the filling 40 arranged in the concave portion 32 of the injection needle 30. Will be. Further, the through hole 41 formed in the filler 40 allows the drug solution lead-out portion 14 of the syringe 10 and the hollow portion of the needle 33 to communicate with each other.

When the assembly of the drug solution injection device 100 is completed, the tip of the needle 33 is pierced into the patient's body, and the piston 21 joined to the plunger 20 is pressed via the operation unit 22 of the syringe 10. As a result, the chemical solution filled in the chamber 13 of the syringe 10 passes through the chemical solution outlet portion 14 and is supplied to the hollow portion of the needle 33 through the through hole 41 of the filler 40. As a result, the drug solution is injected into the patient's body through the hollow portion of the needle 33. By pressing the piston 21, the plunger 20 moves to the front end of the chamber 13, and the chemical injection operation is completed.

Since the space (dead space) between the convex portion 11 and the concave portion 32 is filled by the filling 40 arranged inside the concave portion 32 provided in the injection needle 30, the hollow portion of the needle 33 is filled. The only chemical solution that remains in the dead space without being supplied to the dead space is the chemical solution that is retained in the space of the through hole 41. This makes it possible to significantly reduce the amount of the chemical solution that remains in the dead space without being supplied to the hollow portion of the needle 33. Further, by shielding the chemical liquid outlet portion 14 by the protrusion 23 provided at the tip portion of the plunger 20, the amount of the chemical liquid that stays in the space of the chemical liquid outlet portion 14 without being supplied to the hollow portion of the needle 33 can be further increased. It is possible to reduce it.

As described above, the present invention has been exemplified by using the preferred embodiment of the present invention, but the present invention should not be construed as being limited to this embodiment. It is understood that the invention should be construed only by the claims. It will be understood by those skilled in the art that from the description of the specific preferred embodiments of the present invention, the equivalent scope can be carried out based on the description of the present invention and common general technical knowledge.

The present invention provides a drug solution injection device capable of injecting a drug solution without wasting the drug solution even when a space is created between the syringe and the injection needle, an injection needle used for the device, and the like. It is useful as.

10 Injection needle 11 Convex part 12 Syringe 13 Chamber 14 Chemical solution derivation part 20 Plunger 21 Piston 22 Operation part 23 Protrusion part 30 Injection needle 31 Hub 32 Concave 33 Needle 34 Fitting convex part 35 Through hole 40 Filling hole 41 Through hole

Claims (3)

An injection needle that can be attached and detached to the tip of a syringe.
The syringe comprises a syringe having a chamber filled with a drug solution and a plunger inserted into the chamber of the syringe.
The needle comprises a hub for receiving the tip of the syringe and at least one needle protruding from the tip of the hub.
The tip of the syringe is provided with a tapered protrusion.
The hub has a tapered recess that frictionally engages with the tapered protrusion provided at the tip of the syringe.
The syringe and the injection needle are configured so that when the injection needle is attached to the tip of the syringe, a space is created between the syringe and the injection needle . It is caused by the frictional engagement between the tapered convex portion and the tapered concave portion.
In the syringe and the injection needle, as the plunger of the syringe moves to the anterior end of the chamber of the syringe, the drug solution filled in the chamber of the syringe is supplied to the injection needle through the space. The space is a flow path through which the drug solution flows from the syringe to the injection needle.
The injection needle contains a filling that is filled in a part of the space, and the material of the filling is a material that is not compression-deformed.
Each of the at least one needle has a hollow portion.
The filling has at least one through hole and
The filler is such that when the needle is attached to the tip of the syringe, the drug solution filled in the chamber of the syringe passes through at least one through hole in the filler. It is configured to flow into the hollow portion of each of the at least one needle .
The tapered recess is an injection needle having at least one fitting ridge that mates with the at least one through hole in the filling . The tip of the syringe is provided with a drug solution lead-out portion that guides the drug solution to be filled in the chamber to the injection needle.
The injection needle according to claim 1 , wherein the inner diameter of each of the at least one through hole of the filling is larger than the inner diameter of each hollow portion of the at least one needle and smaller than the inner diameter of the chemical liquid outlet portion. .. A chemical injection device for injecting a chemical solution, wherein the chemical injection device is
A syringe containing a syringe having a chamber filled with a drug solution and a plunger inserted into the chamber of the syringe.
Including a needle that is detachably attached to the tip of the syringe,
The injection needle
A hub for receiving the tip of the syringe,
With at least one needle protruding from the tip of the hub
Including
The tip of the syringe is provided with a tapered protrusion.
The hub has a tapered recess that frictionally engages with the tapered protrusion provided at the tip of the syringe.
The syringe and the needle are configured to create a space between the tip of the syringe and the hub of the needle when the needle is attached to the tip of the syringe. The space is created by the frictional engagement between the tapered convex portion and the tapered concave portion.
In the syringe and the injection needle, as the plunger of the syringe moves to the anterior end of the chamber of the syringe, the drug solution filled in the chamber of the syringe is supplied to the injection needle through the space. The space is a flow path through which the drug solution flows from the syringe to the injection needle.
The injection needle contains a filling that is filled in a part of the space, and the material of the filling is a material that is not compression-deformed.
Each of the at least one needle has a hollow portion.
The filling has at least one through hole and
The filler is such that when the needle is attached to the tip of the syringe, the drug solution filled in the chamber of the syringe passes through at least one through hole in the filler. It is configured to flow into the hollow portion of each of the at least one needle .
The tapered recess is a chemical injection device having at least one fitting protrusion that fits with the at least one through hole of the filling .

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