WO2013145998A1 - Liquid administration set - Google Patents

Liquid administration set Download PDF

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Publication number
WO2013145998A1
WO2013145998A1 PCT/JP2013/054767 JP2013054767W WO2013145998A1 WO 2013145998 A1 WO2013145998 A1 WO 2013145998A1 JP 2013054767 W JP2013054767 W JP 2013054767W WO 2013145998 A1 WO2013145998 A1 WO 2013145998A1
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WO
WIPO (PCT)
Prior art keywords
inner cylinder
assembly
liquid
plunger
administration set
Prior art date
Application number
PCT/JP2013/054767
Other languages
French (fr)
Japanese (ja)
Inventor
滋晃 冨家
正臣 今井
学 有延
Original Assignee
テルモ株式会社
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by テルモ株式会社 filed Critical テルモ株式会社
Publication of WO2013145998A1 publication Critical patent/WO2013145998A1/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M5/2033—Spring-loaded one-shot injectors with or without automatic needle insertion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3202—Devices for protection of the needle before use, e.g. caps

Definitions

  • the present invention relates to a liquid administration set.
  • a liquid administration set that is assembled and used at the time of use is known (for example, see Patent Document 1).
  • the conventional liquid administration set described in Patent Document 1 includes a cartridge in which a chemical solution is stored, a cartridge retainer, an administration device in which a plunger and the like are stored, and a needle device having a double-ended needle.
  • the cartridge In assembling the liquid dosing set, first, the cartridge is inserted into the cartridge retainer, the proximal end of the cartridge retainer is screwed into the dispensing device, and the needle device is screwed into the distal end of the cartridge retainer. .
  • An object of the present invention is to provide a liquid administration set that can be easily assembled.
  • the present invention provides a first assembly that is filled with a liquid and a first assembly that is mounted when in use, and performs an operation of discharging the liquid from the first assembly in the mounted state.
  • a liquid dosing set comprising two assemblies,
  • the first assembly includes a cylindrical outer cylinder,
  • a double-ended needle that is attached to the distal end of the outer cylinder, has a distal needle tip on the distal side, and has a proximal needle tip on the proximal side;
  • An inner cylinder that has a cylindrical shape, has a mouth for discharging the liquid on the tip side, and can move along the axial direction of the outer cylinder in the outer cylinder;
  • a gasket capable of moving along the axial direction of the inner cylinder in the inner cylinder;
  • a sealing portion that is attached to the mouth portion of the inner cylinder, seals a space surrounded by the inner cylinder and the gasket, and allows the proximal end needle tip of the double-ended needle to be pierced;
  • the body A cap that covers at least the tip side needle tip of the double-ended needle of the first assembly body;
  • the second assembly includes a casing having an opening for inserting the first assembly on a distal end side;
  • a plunger that is installed so as to be movable in the axial direction with respect to the casing, and when the liquid administration set is used in the mounted state, a plunger that presses the gasket and moves it in a distal direction.
  • An inner cylinder pressing portion that moves in the distal direction, A second engagement portion supported in the casing and capable of engaging with the first engagement portion at the time of mounting;
  • the proximal needle tip penetrates the sealing portion from a first position where the proximal needle tip of the double-ended needle does not penetrate the sealing portion with respect to the outer cylinder.
  • the inner cylinder Before the mounting, the inner cylinder is located at the first position, At the time of mounting, when the second assembly is moved in the distal direction relative to the first assembly, the inner cylinder is pressed by the inner cylinder pressing portion and moved to the second position, The proximal end needle tip of the double-ended needle pierces the sealing portion, the lumen of the double-ended needle communicates with the inner cylinder, the first engaging portion and the second engaging portion; Is engaged, and the engagement prevents the outer cylinder and the inner cylinder from moving in the distal direction with respect to the casing, and the liquid administration set is configured to be in the mounted state. It is.
  • the second assembly has a biasing means for biasing the plunger in the distal direction.
  • the plunger is moved in the distal direction together with the gasket by the urging force of the urging means, and the liquid is discharged from the double-ended needle. preferable.
  • the first assembly has a plunger pressing portion that presses the plunger and moves it in the proximal direction during the mounting
  • the second assembly has a third engagement portion supported in the casing
  • the plunger has a fourth engagement portion that can be engaged with the third engagement portion during the mounting
  • the casing is provided with an operation member that performs an operation of releasing the engagement between the third engagement portion and the fourth engagement portion.
  • the first assembly has a cylindrical shape with a distal end side closed by a distal end wall, and has a packaging body that houses the first assembly main body therein.
  • the cap is formed on the tip wall; It is preferable that a base end portion of the package constitutes the plunger pressing portion.
  • the plunger has a protrusion that protrudes laterally with respect to its axis, In the mounting, it is preferable that the protrusion is pressed by the plunger pressing portion when the second assembly is moved in the distal direction with respect to the first assembly.
  • the casing has a cylindrical shape whose proximal end is closed by a proximal wall,
  • the third engagement portion is preferably formed on the proximal end wall.
  • the first engagement portion is provided on the proximal end side of the outer cylinder.
  • the casing is provided with a plurality of longitudinally extending arms extending in the axial direction, It is preferable that the second engaging portion is provided on each of the arm portions.
  • the proximal end portion of the inner cylinder protrudes in the proximal direction from the proximal end portion of the outer cylinder, It is preferable that the inner cylinder pressing portion presses a proximal end portion of the inner cylinder.
  • the inner cylinder pressing portion is disposed on an outer periphery of the plunger.
  • the liquid is preferably a chemical solution.
  • the first assembly is inserted into the opening of the casing from the base end side, and the first assembly is attached to the second assembly, thereby enabling the use, that is, Can be assembled.
  • the assembly can be performed easily and rapidly.
  • the member discarded after use can be reduced compared with the past.
  • FIG. 1 is a cross-sectional view showing a liquid cartridge which is a first assembly in the first embodiment of the liquid administration set of the present invention.
  • FIG. 2 is a cross-sectional view showing an administration device which is a second assembly in the first embodiment of the liquid administration set of the present invention.
  • 3 is a cross-sectional view taken along line AA in FIG.
  • FIG. 4 is a cross-sectional view showing an operating state in use in the first embodiment of the liquid administration set of the present invention.
  • FIG. 5 is a sectional view taken along line BB in FIG.
  • FIG. 6 is a cross-sectional view showing an operating state when the liquid administration set shown in FIG. 4 is used.
  • FIG. 7 is a cross-sectional view showing an operating state when the liquid administration set shown in FIG. 4 is used.
  • FIG. 8 is a cross-sectional view showing an operating state when the liquid administration set shown in FIG. 4 is used.
  • FIG. 9 is a cross-sectional view showing an operating state when the liquid administration set shown in FIG. 4 is used.
  • 10 is a cross-sectional view showing an operating state when the liquid administration set shown in FIG. 4 is used.
  • 11 is a cross-sectional view taken along line CC in FIG. 12 is a cross-sectional view showing an operating state when the liquid administration set shown in FIG. 4 is used.
  • FIG. 13 is a perspective view which shows the administration device which is the 2nd assembly in 2nd Embodiment of the liquid administration set of this invention.
  • FIG. 1 is a cross-sectional view showing a liquid cartridge which is a first assembly in the first embodiment of the liquid administration set of the present invention.
  • FIG. 2 is a cross-sectional view showing an administration device which is a second assembly in the first embodiment of the liquid administration set of the present invention.
  • 3 is a cross-sectional view taken along line AA in FIG.
  • FIG. 4 is a cross-sectional view showing an operating state in use in the first embodiment of the liquid administration set of the present invention.
  • FIG. 5 is a sectional view taken along line BB in FIG. 6 to 10 are sectional views showing an operating state when the liquid administration set shown in FIG. 4 is used.
  • 11 is a cross-sectional view taken along line CC in FIG. 12 and 13 are sectional views showing an operating state when the liquid administration set shown in FIG. 4 is used.
  • the upper side in FIGS. 1 to 13 is referred to as “base end (rear end)”, the lower side is referred to as “tip”, and the vertical direction is referred to as “axial direction” or “longitudinal direction”.
  • a liquid administration set 1 includes a liquid cartridge 2 that is a first assembly filled with a liquid, and the liquid cartridge 2 is mounted when in use. And an administration device 3 which is a second assembly for performing an operation of discharging the liquid from the cartridge 2. That is, the liquid administration set 1 is a medical instrument used when a liquid is administered (injected) into a living body in an assembled state in which the liquid cartridge 2 and the administration device 3 are assembled.
  • the liquid is appropriately selected according to the purpose of use. For example, hematopoietic agents, vaccines, hormone preparations, anti-rheumatic agents, anti-cancer agents, anesthetics, anticoagulants, etc. are mainly injected subcutaneously. Chemicals.
  • the liquid cartridge 2 As shown in FIGS. 1 and 5, the liquid cartridge 2 includes a liquid cartridge body 20 and a package 8 that houses the liquid cartridge body 20.
  • the liquid cartridge body 20 includes an outer cylinder 4, a double-ended needle 7 attached to the tip of the outer cylinder 4, an inner cylinder 5 that can move along the axial direction of the outer cylinder 4 within the outer cylinder 4, and an inner cylinder 5 is provided with a gasket 6 that can move along the axial direction of the inner cylinder 5, and a sealing portion 9 that is attached to the tip of the inner cylinder 5.
  • the constituent materials of the outer cylinder 4, the inner cylinder 5, and the package 8 are not particularly limited.
  • Polycarbonate such as polycarbonate, acrylic resin, acrylonitrile-butadiene-styrene copolymer, polyethylene terephthalate, polyethylene naphthalate, etc., butadiene-styrene copolymer, polyamide (for example, nylon 6, nylon 6/6, nylon 6/10, nylon
  • resins such as 12
  • resins such as polypropylene, cyclic polyolefin, polyester, and poly- (4-methylpentene-1) are preferable because they are easy to mold.
  • the outer cylinder 4 is composed of a bottomed cylindrical member, and a mouth part 41 having a diameter reduced with respect to the body part of the outer cylinder 4 is integrally formed at the tip side bottom part, that is, the center part of the tip wall. ing. A double-ended needle 7 is attached to the mouth portion 41.
  • the side wall of the outer cylinder 4 has a cylindrical shape.
  • the base end portion of the outer cylinder 4 is provided with a pair of long arm portions 42 extending in the base end direction from the base end portion and arranged to face each other via the inner cylinder.
  • a protrusion (first engagement portion) 43 is formed at the base end portion of each arm portion 42.
  • the outer surface of the protrusion 43 is an inclined surface whose thickness gradually decreases in the proximal direction.
  • the double-ended needle 7 has a sharp distal end needle tip 71 at the distal end and a sharp proximal end needle tip 72 at the proximal end. Then, the living body can be punctured with the distal needle tip 71, and the sealing portion 9 provided in the mouth 51 of the inner cylinder 5 described later can be pierced with the proximal needle tip 72. Further, the lumen portion (hollow portion) of the double-ended needle 7 communicates with the inner cylinder 5 in a state in which the proximal needle tip 72 is pierced through the sealing portion 9, and the flow path through which the liquid from the inner cylinder 5 passes. Function as. And in the state which punctured the biological body with the tip side needle tip 71, a liquid is inject
  • the constituent material of the double-ended needle 7 is not particularly limited, and is made of, for example, a metal material such as stainless steel, aluminum or an aluminum alloy, titanium or a titanium alloy.
  • An inner cylinder 5 is inserted into the outer cylinder 4 so as to be movable along the axial direction of the outer cylinder 4.
  • the inner cylinder 5 is composed of a bottomed cylindrical member, and a mouth 51 for reducing the diameter of the inner cylinder 5 and discharging the liquid liquid is formed at the bottom of the tip side, that is, at the center of the tip wall.
  • the protrusion is integrally formed.
  • a sealing portion 9 through which the proximal end needle tip 71 of the double-ended needle 7 can be pierced is installed in the mouth portion 51, and the mouth portion 51 is sealed with the sealing portion 9. In this way, the space surrounded by the inner cylinder 5 and a gasket 6 described later is sealed by the sealing portion 9.
  • the side wall of the inner cylinder 5 has a cylindrical shape in this embodiment.
  • the inner cylinder 5 has a proximal needle tip 72 from the first position where the proximal needle tip 72 of the double-ended needle 7 does not penetrate the sealing part 9 with respect to the outer cylinder 4. , And can be moved to a second position where the lumen of the double-ended needle 7 and the inner cylinder 5 communicate with each other.
  • the inner cylinder 5 In an unused state, that is, before the liquid cartridge 2 that is the first assembly is mounted on the administration device 3 that is the second assembly that performs the operation of discharging the liquid from the liquid cartridge 2, the inner cylinder 5 is The base end portion of the inner cylinder 5 protrudes in the base end direction from the base end portion of the outer cylinder 4 (see FIGS. 1 and 5).
  • a gasket 6 having a gasket body 60 made of an elastic material is housed (inserted) so as to be slidable (movable) along the axial direction of the inner cylinder 5.
  • a plurality (two in this embodiment) of ring-shaped protrusions 61 are formed on the entire outer periphery of the gasket body 60, and these protrusions 61 are in close contact with the inner peripheral surface of the inner cylinder 5.
  • the gasket body 60 has a concave portion on the proximal end side, and when the plunger 12 of the administration device 3 to be described later presses the gasket 6 and moves in the distal direction, the plunger main body 60 contacts the plunger 12.
  • the contact part 62 which contacts is inserted.
  • the space surrounded by the gasket 6, the inner cylinder 5, and the sealing portion 9 is filled with liquid. Then, with the proximal needle tip 72 of the double-ended needle 7 penetrating the sealing portion 9, the liquid in the inner cylinder 5 is pushed out from the double-ended needle 7 by the gasket 6 moving toward the distal direction. That is, it can be discharged.
  • the material constituting the gasket body 60 and the sealing portion 9 is not particularly limited.
  • various rubber materials such as natural rubber, butyl rubber, isoprene rubber, butadiene rubber, styrene-butadiene rubber, and silicone rubber, polyurethane-based materials, Examples thereof include various thermoplastic elastomers such as polyester, polyamide, olefin, and styrene, or elastic materials such as a mixture thereof.
  • constituent material of the contact portion 62 is not particularly limited, and examples thereof include the same constituent materials as those of the outer cylinder 4.
  • the package 8 has a cylindrical shape with the tip side closed by a tip wall 81.
  • the side wall of the package 8 has a cylindrical shape in this embodiment.
  • the liquid cartridge main body 20 is accommodated in the package 8. That is, a cap portion 811 having a cylindrical shape is formed on the surface on the proximal end side of the distal end wall 81 so as to protrude toward the proximal end side, and the liquid cartridge main body is formed on the cap portion (cap) 811.
  • the mouth part 41 of the 20 outer cylinders 4 is fitted.
  • the liquid cartridge main body 20 is detachably attached to the cap portion 811 of the package 8, and the distal end needle tip 71 of the double-ended needle 7 is covered with the cap portion 811.
  • the base end portion of the package 8 constitutes a plunger pressing portion that presses the plunger 12 and moves it in the base end direction when the liquid cartridge 2 is mounted.
  • Such a liquid cartridge 2 is attached to the administration device 3 at the time of use.
  • the liquid cartridge 2 is inserted from the proximal end side into an opening 101 of the casing 10 described later of the administration device 3, and the liquid cartridge 2 is attached to the administration device 3.
  • this mounting is also simply referred to as “mounting of the liquid cartridge 2”.
  • the liquid cartridge 2 is preliminarily filled with liquid, but this is not limiting, and the liquid cartridge 2 is not filled with liquid.
  • the liquid cartridge 2 is filled with liquid during use. It may come to be.
  • the administration device 3 includes a casing 10 having an opening 101 into which the liquid cartridge 2 is inserted on the distal end side, an operation member 17 provided outside the casing 10, and a casing.
  • the cylinder 11, the plunger 12, the support member 13, the inner cylinder pressing member 14, the pair of protruding pieces 15, and the coil spring 16 are all housed in the casing 10, but a part of them is housed. Even when projecting to the outside, it is assumed to be accommodated in the casing 10.
  • the casing 10 has a function of a gripping part that is gripped during use, and has a cylindrical shape in which a base end side is closed by a base end wall 102.
  • most of the proximal end wall 102 is curved so as to be convex toward the proximal end, and has a dome shape.
  • the side wall of the casing 10 has a cylindrical shape in the present embodiment.
  • a pair of protruding pieces 15 are formed on the surface of the proximal end wall 102 of the casing 10 so as to protrude toward the distal end side.
  • Each protrusion piece 15 is arrange
  • a protrusion (third engaging portion) 151 is formed at the tip of each protruding piece 15.
  • a cylindrical body 11 having a cylindrical shape whose base end side is closed by a base end wall 111 is fixed to the distal end side of each protruding piece 15.
  • the cylinder 11 is arranged so that the central axis thereof coincides with the central axis of the casing 10. Further, an opening 112 is formed in the central portion of the base end wall 111, and a plunger 12 described later can pass through the opening 12.
  • the plunger 12 is supported so as to be movable in the axial direction, and the support member 13 that engages with the protrusion 43 of the liquid cartridge 2 when the liquid cartridge 2 is mounted. Is fixed.
  • the support member 13 includes a pair of base portions 130 fixed to the base end wall 111 of the cylindrical body 11, four struts 131 formed so as to protrude from the base portions 130 two in the axial direction, and the distal ends of the struts 131. It has a pair of long arm parts 132 which are located on the side and extend in the axial direction, and a pair of connecting parts 133 which connect each support 131 and each arm part 132. Two struts 131 and one arm part 132 are connected by a connecting part 133. The pair of arm portions 132 are disposed so as to oppose each other via the plunger 12.
  • a protrusion (second engaging portion) 134 is formed at the tip of each arm portion 132.
  • the protrusions 43 and the protrusions 134 of the liquid cartridge 2 are engaged so that the protrusions 134 are outside the protrusions 43.
  • tip direction of the outer cylinder 4 with respect to the support member 13 is blocked
  • the inner surface of the protrusion 134 is an inclined surface whose thickness gradually decreases in the distal direction. Further, as described above, since the outer surface of the protrusion 43 is also an inclined surface, the protrusion 43 and the protrusion 134 can smoothly engage with each other.
  • the plunger 12 is on the central axis of the casing 10 and is disposed between the pair of base portions 130 and between the four support columns 131, and is supported by the base portions 130 and the support columns 131 so as to be movable in the axial direction. Yes.
  • the plunger 12 abuts on the gasket 6 and presses the gasket 6 to move in the distal direction.
  • the plunger 12 has projecting portions 121 projecting laterally and on both sides with respect to the shaft. Further, a protrusion 122 (fourth engagement portion) is formed at the proximal end portion of the plunger 12.
  • the protrusion 122 has a conical portion on the tip side. That is, the surface on the distal end side of the protrusion 122 is an inclined surface whose outer diameter gradually decreases in the proximal direction. Thereby, the protrusion 151 and the protrusion 122 can engage smoothly.
  • a coil spring 16 that biases the plunger 12 in the distal direction. Is installed.
  • the coil spring 16 is installed in a slightly contracted state or a natural state.
  • the protruding portion 121 is pressed in the proximal direction by the proximal end portion of the package 8 of the liquid cartridge 2. .
  • the plunger 12 moves in the proximal direction against the urging force of the coil spring 16 and the coil spring 16 contracts.
  • the protrusions 151 of the pair of protruding pieces 15 and the protrusions 122 of the plunger 12 are engaged with each other, whereby the movement of the plunger 12 in the distal direction with respect to the casing 10 is prevented, and the coil spring 16 is kept contracted. Is done.
  • the protruding portion 121 of the plunger 12 abuts on the connecting portion 133 of the support member 13, thereby preventing the plunger 12 from moving in the distal direction.
  • an inner cylinder pressing member 14 that presses the inner cylinder 5 of the liquid cartridge 2 and moves it in the distal direction when the liquid cartridge 2 is mounted is fixed in the casing 10, that is, in the cylinder 11. .
  • the inner cylinder pressing member 14 is provided so as to connect a pair of support portions 141 having a longitudinal shape, which are provided so as to face each other via the plunger 12, and the base end portions of the respective support portions 141. And an inner cylinder pressing portion 142.
  • the inner cylinder pressing portion 142 is a portion that presses the proximal end portion of the inner cylinder 5, and is disposed on the outer periphery of the plunger 12. That is, an opening 143 is formed in the central portion of the inner cylinder pressing portion 142, and the plunger 12 is inserted through the opening.
  • a part of the surface of the bottom plate 102 of the casing 10 is a flat surface, and the operation member 17 is installed on the flat portion of the bottom plate 102 so as to be movable in the left-right direction in FIG.
  • the operation member 17 performs an operation of releasing the engagement between the protrusion 122 of the plunger 12 and the protrusion 151 of the pair of protruding pieces 15.
  • the operation member 17 includes a base 171, a finger-like portion 172 having a plate shape fixed to the base portion 171, and a protruding portion 173 having a plate shape formed in the finger-holding portion 172.
  • the protruding portion 173 protrudes from the finger holding portion 172 in a direction perpendicular to the finger holding portion 172. Then, the width W of the protrusion 173 gradually increases from the right side to the left side in FIG.
  • the operating member 17 is arranged so that the protruding portion 173 is positioned between the pair of protruding pieces 15. In the unused state, the operation member 17 is not in contact with the pair of protruding pieces 15.
  • the projecting portions 173 abut against the pair of projecting pieces 15, and the projecting portions 173 widen the distance between the pair of projecting pieces 15. It has become.
  • the engagement between the protrusion 122 of the plunger 12 and the protrusion 151 of the pair of protruding pieces 15 is released (see FIGS. 10 and 11).
  • a liquid dosing set 1 composed of an unused liquid cartridge 2 and a dosing device 3 shown in FIGS. 1 to 3 is prepared.
  • the inner cylinder 5 of the liquid cartridge 2 is located at the first position as shown in FIGS. 1 and 5, and the proximal end needle tip 72 of the double-ended needle 7 is sealed.
  • the stop portion 9 is not pierced, and the proximal end portion of the inner cylinder 5 protrudes from the proximal end portion of the outer tube 4 in the proximal direction.
  • the casing 10 is gripped, and the liquid cartridge 2 is inserted into the opening 101 of the administration device 3 from the proximal end side.
  • the alignment is performed so that the projection 134 of the arm portion 132 on the administration device 3 side corresponds to the projection 43 of the arm portion 42 on the liquid cartridge 2 side.
  • the administration device 3 is pressed in the distal direction, the administration device 3 is moved in the distal direction with respect to the liquid cartridge 2, and the liquid cartridge 2 is attached to the administration device 3.
  • the following operation occurs, and the liquid cartridge 2 is attached to the administration device 3.
  • the protruding portion 121 of the plunger 12 of the administration device 3 comes into contact with the proximal end portion of the packaging body 8 of the liquid cartridge 2, and the packaging body 8.
  • the protruding portion 121 is pressed in the proximal direction by the proximal end portion. 6 and 7, the plunger 12 moves in the proximal direction against the biasing force of the coil spring 16, and the coil spring 16 contracts.
  • the movement of the administration device 3 causes the projections 43 of the liquid cartridge 2 and the projections 134 of the administration device 3 to engage with each other. Thereby, the movement to the front-end
  • the movement of the administration device 3 causes the inner cylinder pressing portion 142 of the inner cylinder pressing member 14 of the administration device 3 to come into contact with the proximal end portion of the inner cylinder 5 of the liquid cartridge 2.
  • the inner cylinder pressing portion 142 presses the inner cylinder 5 in the distal direction.
  • the inner cylinder 5 moves in the distal direction, that is, moves to the second position, and the proximal needle tip 72 of the double-ended needle 7 penetrates the sealing portion 9, The lumen of the double-ended needle 7 and the inner cylinder 5 communicate with each other.
  • the protrusion 122 of the plunger 12 of the liquid cartridge 2 passes between the protrusions 151 of the pair of protruding pieces 15 of the administration device 3, moves to the proximal side of the protrusion 151, and A gap is formed between the protrusion 122 and the protrusion 151.
  • the plunger 12 moves in the distal direction by the urging force of the coil spring 16, and the projections 151 and the projections 122 are engaged with each other. The movement of the plunger 12 in the distal direction is prevented, and the coil spring 16 is kept contracted (see FIG. 9).
  • the package 8 is pulled in the distal direction, and the package 8 is removed from the liquid cartridge body 20.
  • the mounting of the liquid cartridge 2 is completed.
  • the double-ended needle 7 projects from the distal end of the casing in the distal direction.
  • the urging force of the coil spring 16 moves the plunger 12 in the distal direction, and the gasket 6 is pressed in the distal direction together with the plunger 12, and the gasket 6 moves in the inner cylinder 5 in the distal direction.
  • the liquid in the inner cylinder 5 is discharged
  • the liquid cartridge 2 is removed from the administration device 3 and discarded.
  • this liquid administration set 1 just by inserting the liquid cartridge 2 into the opening 101 of the casing 10 from the proximal end side and moving the administration device 3 in the distal direction with respect to the liquid cartridge 2,
  • the liquid cartridge 2 can be attached to the administration device 3. That is, the liquid administration set 1 can be assembled. Thereby, the assembly can be performed easily and rapidly.
  • positioning means for positioning the projection 134 of the arm portion 132 on the administration device 3 side and the projection 43 of the arm portion 42 on the liquid cartridge 2 side when the liquid cartridge 2 is mounted may be provided.
  • This positioning means can be constituted by, for example, a groove provided in one of the liquid cartridge 2 and the administration device 3 and a protrusion or rib provided in the other.
  • the number of the protrusions 134 on the administration device 3 side is two, but is not limited thereto, and may be three or more.
  • the number of the protrusions 43 on the liquid cartridge 2 side is two, but the number is not limited thereto, and may be three or more.
  • the number of protrusions 134 on the administration device 3 side and the number of protrusions 43 on the liquid cartridge 2 side are the same, but they may be different.
  • the protrusion 134 on the administration device 3 side may be formed over the entire circumference of the outer cylinder 4. That is, the first engaging portion may be a rib formed over one circumference of the outer cylinder 4.
  • the 1st engaging part is provided in the outer cylinder, in this invention, not only this but the 1st engaging part is provided in the inner cylinder, for example. Also good.
  • FIG. 13 is a perspective view which shows the administration device which is the 2nd assembly in 2nd Embodiment of the liquid administration set of this invention.
  • the left side in FIG. 13 is described as “upper end (rear end)” on the upper side, “front end” on the lower side, and “axial direction” or “longitudinal direction” on the vertical direction.
  • the second embodiment is the same as the first embodiment except that the configuration of the administration device 3 is different.
  • the administration device 3 is configured to manually move the plunger 12.
  • the administration device 3 includes a casing 10, a plunger 12 provided in the casing, a pair of arm portions 132, and an inner cylinder pressing member 14.
  • a disc-shaped flange 123 is formed at the base end portion of the plunger 12.
  • liquid administration set of the present invention has been described based on the illustrated embodiment.
  • the present invention is not limited to this, and the configuration of each part is replaced with an arbitrary configuration having the same function. can do.
  • other arbitrary structures and processes may be added to the present invention.
  • the present invention may be a combination of any two or more configurations (features) of the above embodiments.
  • the liquid dosing set includes a first assembly that is filled with a liquid, and the first assembly is mounted during use, and the liquid is discharged from the first assembly in the mounted state.
  • a liquid dosing set comprising a second assembly for operation,
  • the first assembly includes a cylindrical outer cylinder, A double-ended needle that is attached to the distal end of the outer cylinder, has a distal needle tip on the distal side, and has a proximal needle tip on the proximal side;
  • An inner cylinder that has a cylindrical shape, has a mouth for discharging the liquid on the tip side, and can move along the axial direction of the outer cylinder in the outer cylinder;
  • a gasket capable of moving along the axial direction of the inner cylinder in the inner cylinder;
  • a sealing portion that is attached to the mouth portion of the inner cylinder, seals a space surrounded by the inner cylinder and the gasket, and allows the proximal end needle tip of the double-ended needle to be pierced;
  • the body A cap that covers at least the tip side needle tip of the double-ended needle of the first assembly body;
  • the second assembly includes a casing having an opening for inserting the first assembly on a distal end side;
  • a plunger that is installed so as to be movable in the axial direction with respect to the casing, and when the liquid administration set is used in the mounted state, a plunger that presses the gasket and moves it in a distal direction.
  • An inner cylinder pressing portion that moves in the distal direction, A second engagement portion supported in the casing and capable of engaging with the first engagement portion at the time of mounting;
  • the proximal needle tip penetrates the sealing portion from a first position where the proximal needle tip of the double-ended needle does not penetrate the sealing portion with respect to the outer cylinder.
  • the inner cylinder Before the mounting, the inner cylinder is located at the first position, During the mounting, when the second assembly is moved in the distal direction with respect to the first assembly, the inner cylinder is pressed by the inner cylinder pressing portion and moved to the second position, The proximal end needle tip of the double-ended needle pierces the sealing portion, the lumen of the double-ended needle communicates with the inner cylinder, the first engaging portion and the second engaging portion; Is engaged, and the engagement prevents the outer cylinder and the inner cylinder from moving in the distal direction with respect to the casing, and the mounting state is established.
  • the first assembly is inserted into the opening of the casing from the proximal end side, and the first assembly is attached to the second assembly, thereby enabling the use, that is, Can be assembled.
  • the assembly can be performed easily and rapidly.
  • the member discarded after use can be reduced compared with the past. Therefore, it has industrial applicability.

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Abstract

This liquid administration set (1) is provided with: a liquid cartridge (2) filled with a liquid; and an administration device (3) to which the liquid cartridge (2) is installed at the time of use, and that, in the state of installation thereof, performs an operation of discharging the liquid from the liquid cartridge (2). The liquid cartridge (2) is provided with a liquid cartridge main body (20) and a wrapping body (8), and the liquid cartridge main body (20) is provided with: an outer tube (4); a double-ended needle (7) installed at the tip of the outer tube (4); an inner tube (5); a gasket (6); and a sealing section (9) installed at the tip of the inner tube (5). The administration device (3) is provided with: a casing (10) having at the tip side an opening (101) through which the liquid cartridge (2) is inserted; and, provided in the casing (10), a tube body (11), a plunger (12), a support member (13), an inner tube pressing member (14), a pair of protruding pieces (15), and a coil spring (16).

Description

液体投与セットLiquid dosing set
　本発明は、液体投与セットに関するものである。 The present invention relates to a liquid administration set.
　使用時に組み立てて使用する液体投与セットが知られている（例えば、特許文献１参照）。 A liquid administration set that is assembled and used at the time of use is known (for example, see Patent Document 1).
　特許文献１に記載の従来の液体投与セットは、薬液が収納されたカートリッジと、カートリッジ・リテーナと、プランジャ等が収納された投与デバイスと、両頭針を有する針デバイスとで構成されている。 The conventional liquid administration set described in Patent Document 1 includes a cartridge in which a chemical solution is stored, a cartridge retainer, an administration device in which a plunger and the like are stored, and a needle device having a double-ended needle.
　この液体投与セットの組み立てにおいて、まず、カートリッジをカートリッジ・リテーナに挿入し、そのカートリッジ・リテーナの基端部を投与デバイスに螺合し、さらに、カートリッジ・リテーナの先端部に針デバイスを螺合する。 In assembling the liquid dosing set, first, the cartridge is inserted into the cartridge retainer, the proximal end of the cartridge retainer is screwed into the dispensing device, and the needle device is screwed into the distal end of the cartridge retainer. .
　しかしながら、このような従来の液体投与セットでは、組立工程が多く、その組み立てが煩雑であり、組み立てに手間がかかるという問題がある。 However, such a conventional liquid dosing set has a problem that the assembly process is many, the assembly is complicated, and the assembly takes time.
特開平１１－１０４２４０号公報JP-A-11-104240
　本発明の目的は、組み立てを容易に行うことができる液体投与セットを提供することにある。 An object of the present invention is to provide a liquid administration set that can be easily assembled.
　このような目的は、下記の本発明により達成される。
　本発明は、液体が充填される第１の組立体と、使用時に、該第１の組立体が装着され、その装着状態で、前記第１の組立体から前記液体を排出する操作を行う第２の組立体とを備える液体投与セットであって、
　前記第１の組立体は、筒状をなす外筒と、
　前記外筒の先端部に装着され、先端側に先端側針先を有し、基端側に基端側針先を有する両頭針と、
　筒状をなし、先端側に前記液体を排出する口部を有し、前記外筒内で該外筒の軸方向に沿って移動し得る内筒と、
　前記内筒内で該内筒の軸方向に沿って移動し得るガスケットと、
　前記内筒の前記口部に装着され、前記内筒と前記ガスケットとで囲まれる空間を封止し、前記両頭針の前記基端側針先が刺通し得る封止部と、
　前記外筒または前記内筒に設けられた第１の係合部とを備え、前記内筒と前記ガスケットと前記封止部とで囲まれた空間に前記液体が充填される第１の組立体本体と、
　前記第１の組立体本体の前記両頭針の少なくとも前記先端側針先を覆うキャップとを具備し、
　前記第２の組立体は、前記第１の組立体を挿入する開口を先端側に有するケーシングと、
　前記ケーシングに対して、軸方向に移動可能に設置され、前記装着状態で当該液体投与セットを使用する際に、前記ガスケットを押圧して先端方向に移動させるプランジャと、
　前記ケーシング内に支持され、前記開口に前記第１の組立体を基端側から挿入して前記第１の組立体を前記第２の組立体に装着する際に、前記内筒を押圧して先端方向に移動させる内筒押圧部と、
　前記ケーシング内に支持され、前記装着の際に、前記第１の係合部と係合し得る第２の係合部と具備し、
　前記内筒は、前記外筒に対して、前記両頭針の前記基端側針先が前記封止部を刺通していない第１の位置から、前記基端側針先が前記封止部を刺通して、前記両頭針の内腔と前記内筒とが連通する第２の位置に移動可能であり、
　前記装着前は、前記内筒は、前記第１の位置に位置し、
　前記装着の際、前記第２の組立体を前記第１の組立体に対して先端方向に移動させると、前記内筒押圧部により、前記内筒が押圧されて第２の位置に移動し、前記両頭針の前記基端側針先が前記封止部を刺通して、前記両頭針の内腔と前記内筒とが連通し、前記第１の係合部と前記第２の係合部とが係合し、この係合により前記ケーシングに対して前記外筒および前記内筒が先端方向に移動することが阻止され、前記装着状態となるよう構成されていることを特徴とする液体投与セットである。 Such an object is achieved by the present invention described below.
The present invention provides a first assembly that is filled with a liquid and a first assembly that is mounted when in use, and performs an operation of discharging the liquid from the first assembly in the mounted state. A liquid dosing set comprising two assemblies,
The first assembly includes a cylindrical outer cylinder,
A double-ended needle that is attached to the distal end of the outer cylinder, has a distal needle tip on the distal side, and has a proximal needle tip on the proximal side;
An inner cylinder that has a cylindrical shape, has a mouth for discharging the liquid on the tip side, and can move along the axial direction of the outer cylinder in the outer cylinder;
A gasket capable of moving along the axial direction of the inner cylinder in the inner cylinder;
A sealing portion that is attached to the mouth portion of the inner cylinder, seals a space surrounded by the inner cylinder and the gasket, and allows the proximal end needle tip of the double-ended needle to be pierced;
A first assembly that includes a first engagement portion provided on the outer cylinder or the inner cylinder, and in which a space surrounded by the inner cylinder, the gasket, and the sealing portion is filled with the liquid. The body,
A cap that covers at least the tip side needle tip of the double-ended needle of the first assembly body;
The second assembly includes a casing having an opening for inserting the first assembly on a distal end side;
A plunger that is installed so as to be movable in the axial direction with respect to the casing, and when the liquid administration set is used in the mounted state, a plunger that presses the gasket and moves it in a distal direction.
When the first assembly is inserted into the opening from the proximal end side and the first assembly is mounted on the second assembly, the inner cylinder is pressed. An inner cylinder pressing portion that moves in the distal direction,
A second engagement portion supported in the casing and capable of engaging with the first engagement portion at the time of mounting;
In the inner cylinder, the proximal needle tip penetrates the sealing portion from a first position where the proximal needle tip of the double-ended needle does not penetrate the sealing portion with respect to the outer cylinder. And can be moved to a second position where the lumen of the double-ended needle and the inner cylinder communicate with each other,
Before the mounting, the inner cylinder is located at the first position,
At the time of mounting, when the second assembly is moved in the distal direction relative to the first assembly, the inner cylinder is pressed by the inner cylinder pressing portion and moved to the second position, The proximal end needle tip of the double-ended needle pierces the sealing portion, the lumen of the double-ended needle communicates with the inner cylinder, the first engaging portion and the second engaging portion; Is engaged, and the engagement prevents the outer cylinder and the inner cylinder from moving in the distal direction with respect to the casing, and the liquid administration set is configured to be in the mounted state. It is.
　本発明の液体投与セットでは、前記第２の組立体は、前記プランジャを先端方向に付勢する付勢手段を有し、
　前記装着状態で当該液体投与セットを使用する際、前記付勢手段の付勢力により前記プランジャが前記ガスケットとともに先端方向に移動し、前記両頭針から前記液体が排出されるよう構成されていることが好ましい。 In the liquid administration set of the present invention, the second assembly has a biasing means for biasing the plunger in the distal direction.
When the liquid administration set is used in the mounted state, the plunger is moved in the distal direction together with the gasket by the urging force of the urging means, and the liquid is discharged from the double-ended needle. preferable.
　本発明の液体投与セットでは、前記第１の組立体は、前記装着の際に、前記プランジャを押圧して基端方向に移動させるプランジャ押圧部を有し、
　前記第２の組立体は、前記ケーシング内に支持された第３の係合部を有し、
　前記プランジャは、前記装着の際に、前記第３の係合部と係合し得る第４の係合部を有し、
　前記装着の際、前記第２の組立体を前記第１の組立体に対して先端方向に移動させると、前記付勢手段の付勢力に抗して、前記プランジャ押圧部により、前記プランジャが押圧されて基端方向に移動し、前記第３の係合部と前記第４の係合部とが係合し、この係合により前記ケーシングに対して前記プランジャが先端方向に移動することが阻止されるよう構成されていることが好ましい。 In the liquid administration set of the present invention, the first assembly has a plunger pressing portion that presses the plunger and moves it in the proximal direction during the mounting,
The second assembly has a third engagement portion supported in the casing,
The plunger has a fourth engagement portion that can be engaged with the third engagement portion during the mounting,
When the second assembly is moved in the distal direction relative to the first assembly during the mounting, the plunger is pressed by the plunger pressing portion against the urging force of the urging means. Is moved in the proximal direction, and the third engagement portion and the fourth engagement portion are engaged, and the engagement prevents the plunger from moving in the distal direction with respect to the casing. It is preferable to be configured.
　本発明の液体投与セットでは、前記ケーシングには、前記第３の係合部と前記第４の係合部との係合を解除する操作を行う操作部材が設けられていることが好ましい。 In the liquid administration set of the present invention, it is preferable that the casing is provided with an operation member that performs an operation of releasing the engagement between the third engagement portion and the fourth engagement portion.
　本発明の液体投与セットでは、前記第１の組立体は、先端側が先端壁で閉じられた筒状をなし、その内部に前記第１の組立体本体を収納する包装体を有し、
　前記キャップは、前記先端壁に形成されており、
　前記包装体の基端部が、前記プランジャ押圧部を構成していることが好ましい。 In the liquid administration set of the present invention, the first assembly has a cylindrical shape with a distal end side closed by a distal end wall, and has a packaging body that houses the first assembly main body therein.
The cap is formed on the tip wall;
It is preferable that a base end portion of the package constitutes the plunger pressing portion.
　本発明の液体投与セットでは、前記プランジャは、その軸に対して側方に突出する突出部を有し、
　前記装着の際、前記第２の組立体を前記第１の組立体に対して先端方向に移動させると、前記プランジャ押圧部により、前記突出部が押圧されるよう構成されていることが好ましい。 In the liquid administration set of the present invention, the plunger has a protrusion that protrudes laterally with respect to its axis,
In the mounting, it is preferable that the protrusion is pressed by the plunger pressing portion when the second assembly is moved in the distal direction with respect to the first assembly.
　本発明の液体投与セットでは、前記ケーシングは、基端側が基端壁で閉じられた筒状をなし、
　前記第３の係合部は、前記基端壁に形成されていることが好ましい。 In the liquid administration set of the present invention, the casing has a cylindrical shape whose proximal end is closed by a proximal wall,
The third engagement portion is preferably formed on the proximal end wall.
　本発明の液体投与セットでは、前記第１の係合部は、前記外筒の基端側に設けられていることが好ましい。 In the liquid administration set of the present invention, it is preferable that the first engagement portion is provided on the proximal end side of the outer cylinder.
　本発明の液体投与セットでは、前記ケーシングには、軸方向に延びる長手形状の複数の腕部が設けられており、
　前記第２の係合部は、前記各腕部にそれぞれ設けられていることが好ましい。 In the liquid administration set of the present invention, the casing is provided with a plurality of longitudinally extending arms extending in the axial direction,
It is preferable that the second engaging portion is provided on each of the arm portions.
　本発明の液体投与セットでは、前記未使用状態では、前記内筒の基端部は、前記外筒の基端部から基端方向に突出しており、
　前記内筒押圧部は、前記内筒の基端部を押圧するものであることが好ましい。 In the liquid administration set of the present invention, in the unused state, the proximal end portion of the inner cylinder protrudes in the proximal direction from the proximal end portion of the outer cylinder,
It is preferable that the inner cylinder pressing portion presses a proximal end portion of the inner cylinder.
　本発明の液体投与セットでは、前記内筒押圧部は、前記プランジャの外周に配置されていることが好ましい。
　本発明の液体投与セットでは、前記液体が薬液であることが好ましい。 In the liquid administration set of the present invention, it is preferable that the inner cylinder pressing portion is disposed on an outer periphery of the plunger.
In the liquid administration set of the present invention, the liquid is preferably a chemical solution.
　本発明によれば、ケーシングの開口に第１の組立体を基端側から挿入して第１の組立体を第２の組立体に装着することにより、使用可能な状態とすること、すなわち、組み立てることができる。これにより、その組み立てを容易かつ迅速に行うことができる。
　また、従来に比べて、使用後に破棄される部材を削減することができる。 According to the present invention, the first assembly is inserted into the opening of the casing from the base end side, and the first assembly is attached to the second assembly, thereby enabling the use, that is, Can be assembled. Thereby, the assembly can be performed easily and rapidly.
Moreover, the member discarded after use can be reduced compared with the past.
図１は、本発明の液体投与セットの第１実施形態における第１の組立体である液体カートリッジを示す断面図である。FIG. 1 is a cross-sectional view showing a liquid cartridge which is a first assembly in the first embodiment of the liquid administration set of the present invention. 図２は、本発明の液体投与セットの第１実施形態における第２の組立体である投与デバイスを示す断面図である。FIG. 2 is a cross-sectional view showing an administration device which is a second assembly in the first embodiment of the liquid administration set of the present invention. 図３は、図２中のＡ－Ａ線断面図である。3 is a cross-sectional view taken along line AA in FIG. 図４は、本発明の液体投与セットの第１実施形態における使用時の作動状態を示す断面図である。FIG. 4 is a cross-sectional view showing an operating state in use in the first embodiment of the liquid administration set of the present invention. 図５は、図４中のＢ－Ｂ線断面図である。FIG. 5 is a sectional view taken along line BB in FIG. 図６は、図４に示す液体投与セットの使用時の作動状態を示す断面図である。FIG. 6 is a cross-sectional view showing an operating state when the liquid administration set shown in FIG. 4 is used. 図７は、図４に示す液体投与セットの使用時の作動状態を示す断面図である。FIG. 7 is a cross-sectional view showing an operating state when the liquid administration set shown in FIG. 4 is used. 図８は、図４に示す液体投与セットの使用時の作動状態を示す断面図である。FIG. 8 is a cross-sectional view showing an operating state when the liquid administration set shown in FIG. 4 is used. 図９は、図４に示す液体投与セットの使用時の作動状態を示す断面図である。FIG. 9 is a cross-sectional view showing an operating state when the liquid administration set shown in FIG. 4 is used. 図１０は、図４に示す液体投与セットの使用時の作動状態を示す断面図である。10 is a cross-sectional view showing an operating state when the liquid administration set shown in FIG. 4 is used. 図１１は、図１０中のＣ－Ｃ線断面図である。11 is a cross-sectional view taken along line CC in FIG. 図１２は、図４に示す液体投与セットの使用時の作動状態を示す断面図である。12 is a cross-sectional view showing an operating state when the liquid administration set shown in FIG. 4 is used. 図１３は、本発明の液体投与セットの第２実施形態における第２の組立体である投与デバイスを示す斜視図である。FIG. 13: is a perspective view which shows the administration device which is the 2nd assembly in 2nd Embodiment of the liquid administration set of this invention.
　以下、本発明の液体投与セットを添付図面に示す好適な実施形態に基づいて詳細に説明する。 Hereinafter, the liquid administration set of the present invention will be described in detail based on preferred embodiments shown in the accompanying drawings.
　＜第１実施形態＞
　図１は、本発明の液体投与セットの第１実施形態における第１の組立体である液体カートリッジを示す断面図である。図２は、本発明の液体投与セットの第１実施形態における第２の組立体である投与デバイスを示す断面図である。図３は、図２中のＡ－Ａ線断面図である。図４は、本発明の液体投与セットの第１実施形態における使用時の作動状態を示す断面図である。図５は、図４中のＢ－Ｂ線断面図である。図６～図１０は、図４に示す液体投与セットの使用時の作動状態を示す断面図である。図１１は、図１０中のＣ－Ｃ線断面図である。図１２および図１３は、図４に示す液体投与セットの使用時の作動状態を示す断面図である。 <First Embodiment>
FIG. 1 is a cross-sectional view showing a liquid cartridge which is a first assembly in the first embodiment of the liquid administration set of the present invention. FIG. 2 is a cross-sectional view showing an administration device which is a second assembly in the first embodiment of the liquid administration set of the present invention. 3 is a cross-sectional view taken along line AA in FIG. FIG. 4 is a cross-sectional view showing an operating state in use in the first embodiment of the liquid administration set of the present invention. FIG. 5 is a sectional view taken along line BB in FIG. 6 to 10 are sectional views showing an operating state when the liquid administration set shown in FIG. 4 is used. 11 is a cross-sectional view taken along line CC in FIG. 12 and 13 are sectional views showing an operating state when the liquid administration set shown in FIG. 4 is used.
　なお、以下では、図１～図１３中の上側を「基端（後端）」、下側を「先端」、上下方向を「軸方向」または「長手方向」として説明を行う。 In the following description, the upper side in FIGS. 1 to 13 is referred to as “base end (rear end)”, the lower side is referred to as “tip”, and the vertical direction is referred to as “axial direction” or “longitudinal direction”.
　図１～図６に示すように、液体投与セット１は、液体が充填された第１の組立体である液体カートリッジ２と、使用時に、その液体カートリッジ２が装着され、その装着状態で、液体カートリッジ２から液体を排出する操作を行う第２の組立体である投与デバイス３とを備えている。すなわち、液体投与セット１は、液体カートリッジ２と投与デバイス３とを組み立てた組立状態で、液体を生体に投与する（注入する）際に用いられる医療器具である。なお、液体としては、その使用目的に応じて適宜選択されるが、例えば、造血剤、ワクチン、ホルモン製剤、抗リウマチ剤、抗ガン剤、麻酔剤、血液凝固防止剤等、主に皮下注射される薬液が挙げられる。 As shown in FIGS. 1 to 6, a liquid administration set 1 includes a liquid cartridge 2 that is a first assembly filled with a liquid, and the liquid cartridge 2 is mounted when in use. And an administration device 3 which is a second assembly for performing an operation of discharging the liquid from the cartridge 2. That is, the liquid administration set 1 is a medical instrument used when a liquid is administered (injected) into a living body in an assembled state in which the liquid cartridge 2 and the administration device 3 are assembled. The liquid is appropriately selected according to the purpose of use. For example, hematopoietic agents, vaccines, hormone preparations, anti-rheumatic agents, anti-cancer agents, anesthetics, anticoagulants, etc. are mainly injected subcutaneously. Chemicals.
　まず、液体カートリッジ２について説明する。
　図１および図５に示すように、液体カートリッジ２は、液体カートリッジ本体２０と、その液体カートリッジ本体２０を収納する包装体８とを備えている。 First, the liquid cartridge 2 will be described.
As shown in FIGS. 1 and 5, the liquid cartridge 2 includes a liquid cartridge body 20 and a package 8 that houses the liquid cartridge body 20.
　液体カートリッジ本体２０は、外筒４と、外筒４の先端部に装着された両頭針７と、外筒４内で外筒４の軸方向に沿って移動し得る内筒５と、内筒５内で内筒５の軸方向に沿って移動し得るガスケット６と、内筒５の先端部に装着された封止部９とを備えている。 The liquid cartridge body 20 includes an outer cylinder 4, a double-ended needle 7 attached to the tip of the outer cylinder 4, an inner cylinder 5 that can move along the axial direction of the outer cylinder 4 within the outer cylinder 4, and an inner cylinder 5 is provided with a gasket 6 that can move along the axial direction of the inner cylinder 5, and a sealing portion 9 that is attached to the tip of the inner cylinder 5.
　なお、外筒４、内筒５、包装体８の構成材料としては、特に限定されず、例えば、ポリ塩化ビニル、ポリエチレン、ポリプロピレン、環状ポリオレフィン、ポリスチレン、ポリ－（４－メチルペンテン－１）、ポリカーボネート、アクリル樹脂、アクリルニトリル－ブタジエン－スチレン共重合体、ポリエチレンテレフタレート、ポリエチレンナフタレート等のポリエステル、ブタジエン－スチレン共重合体、ポリアミド（例えば、ナイロン６、ナイロン６・６、ナイロン６・１０、ナイロン１２）のような各種樹脂が挙げられるが、その中でも、成形が容易であるという点で、ポリプロピレン、環状ポリオレフィン、ポリエステル、ポリ－（４－メチルペンテン－１）のような樹脂が好ましい。 The constituent materials of the outer cylinder 4, the inner cylinder 5, and the package 8 are not particularly limited. For example, polyvinyl chloride, polyethylene, polypropylene, cyclic polyolefin, polystyrene, poly- (4-methylpentene-1), Polycarbonate such as polycarbonate, acrylic resin, acrylonitrile-butadiene-styrene copolymer, polyethylene terephthalate, polyethylene naphthalate, etc., butadiene-styrene copolymer, polyamide (for example, nylon 6, nylon 6/6, nylon 6/10, nylon Various resins such as 12) can be mentioned. Among them, resins such as polypropylene, cyclic polyolefin, polyester, and poly- (4-methylpentene-1) are preferable because they are easy to mold.
　外筒４は、有底筒状の部材で構成され、先端側底部、すなわち、先端壁の中央部には、外筒４の胴部に対し縮径した口部４１が一体的に突出形成されている。そして、その口部４１に、両頭針７が装着されている。なお、外筒４の側壁は、本実施形態では、円筒状をなしている。 The outer cylinder 4 is composed of a bottomed cylindrical member, and a mouth part 41 having a diameter reduced with respect to the body part of the outer cylinder 4 is integrally formed at the tip side bottom part, that is, the center part of the tip wall. ing. A double-ended needle 7 is attached to the mouth portion 41. In the present embodiment, the side wall of the outer cylinder 4 has a cylindrical shape.
　外筒４の基端部には、基端部から基端方向に延び、内筒を介して互いに対向するように配置された長手形状の一対の腕部４２が設けられている。そして、各腕部４２の基端部には、それぞれ、突起（第１の係合部）４３が形成されている。なお、突起４３の外面は、その厚さが基端方向に向かって漸減する傾斜面になっている。 The base end portion of the outer cylinder 4 is provided with a pair of long arm portions 42 extending in the base end direction from the base end portion and arranged to face each other via the inner cylinder. A protrusion (first engagement portion) 43 is formed at the base end portion of each arm portion 42. The outer surface of the protrusion 43 is an inclined surface whose thickness gradually decreases in the proximal direction.
　両頭針７は、その先端に鋭利な先端側針先７１を有し、また、その基端に鋭利な基端側針先７２を有している。そして、先端側針先７１で生体を穿刺することができ、また、基端側針先７２で後述する内筒５の口部５１に設けられた封止部９を刺通することができる。また、両頭針７の内腔部（中空部）は、基端側針先７２が封止部９を刺通した状態で内筒５と連通し、内筒５からの液体が通過する流路として機能する。そして、先端側針先７１で生体を穿刺した状態で、その生体に前記流路を介して液体が注入される。 The double-ended needle 7 has a sharp distal end needle tip 71 at the distal end and a sharp proximal end needle tip 72 at the proximal end. Then, the living body can be punctured with the distal needle tip 71, and the sealing portion 9 provided in the mouth 51 of the inner cylinder 5 described later can be pierced with the proximal needle tip 72. Further, the lumen portion (hollow portion) of the double-ended needle 7 communicates with the inner cylinder 5 in a state in which the proximal needle tip 72 is pierced through the sealing portion 9, and the flow path through which the liquid from the inner cylinder 5 passes. Function as. And in the state which punctured the biological body with the tip side needle tip 71, a liquid is inject | poured into the biological body through the said flow path.
　両頭針７の構成材料としては、特に限定されず、例えば、ステンレス鋼、アルミニウムまたはアルミニウム合金、チタンまたはチタン合金のような金属材料で構成されている。
　外筒４内には、内筒５が外筒４の軸方向に沿って移動可能に挿入されている。 The constituent material of the double-ended needle 7 is not particularly limited, and is made of, for example, a metal material such as stainless steel, aluminum or an aluminum alloy, titanium or a titanium alloy.
An inner cylinder 5 is inserted into the outer cylinder 4 so as to be movable along the axial direction of the outer cylinder 4.
　内筒５は、有底筒状の部材で構成され、先端側底部、すなわち、先端壁の中央部には、内筒５の胴部に対し縮径し、液体液を排出する口部５１が一体的に突出形成されている。そして、この口部５１に、両頭針７の基端側針先７１が刺通し得る封止部９が設置され、口部５１は、その封止部９で封止されている。このようにして、封止部９により、内筒５と後述するガスケット６とで囲まれる空間が封止される。なお、内筒５の側壁は、本実施形態では、円筒状をなしている。 The inner cylinder 5 is composed of a bottomed cylindrical member, and a mouth 51 for reducing the diameter of the inner cylinder 5 and discharging the liquid liquid is formed at the bottom of the tip side, that is, at the center of the tip wall. The protrusion is integrally formed. A sealing portion 9 through which the proximal end needle tip 71 of the double-ended needle 7 can be pierced is installed in the mouth portion 51, and the mouth portion 51 is sealed with the sealing portion 9. In this way, the space surrounded by the inner cylinder 5 and a gasket 6 described later is sealed by the sealing portion 9. In addition, the side wall of the inner cylinder 5 has a cylindrical shape in this embodiment.
　また、内筒５は、外筒４に対して、両頭針７の基端側針先７２が封止部９を刺通していない第１の位置から、基端側針先７２が封止部９を刺通して、両頭針７の内腔と内筒５とが連通する第２の位置に移動可能になっている。 Further, the inner cylinder 5 has a proximal needle tip 72 from the first position where the proximal needle tip 72 of the double-ended needle 7 does not penetrate the sealing part 9 with respect to the outer cylinder 4. , And can be moved to a second position where the lumen of the double-ended needle 7 and the inner cylinder 5 communicate with each other.
　未使用状態、つまり、第１の組立体である液体カートリッジ２が、液体カートリッジ２から液体を排出する操作を行う第２の組立体である投与デバイス３に装着される前では、内筒５は、第１の位置に位置し、内筒５の基端部は、外筒４の基端部から基端方向に突出している（図１、図５参照）。 In an unused state, that is, before the liquid cartridge 2 that is the first assembly is mounted on the administration device 3 that is the second assembly that performs the operation of discharging the liquid from the liquid cartridge 2, the inner cylinder 5 is The base end portion of the inner cylinder 5 protrudes in the base end direction from the base end portion of the outer cylinder 4 (see FIGS. 1 and 5).
　このような内筒５内には、弾性材料で構成されたガスケット本体６０を有するガスケット６が内筒５の軸方向に沿って摺動可能（移動可能）に収納されて（挿入されて）いる。ガスケット本体６０の外周部には、複数（本実施形態では２つ）のリング状の突部６１が全周にわたって形成されており、これらの突部６１が内筒５の内周面に密着しつつ摺動することで、液密性をより確実に保持するとともに、摺動性の向上が図れる。 In the inner cylinder 5, a gasket 6 having a gasket body 60 made of an elastic material is housed (inserted) so as to be slidable (movable) along the axial direction of the inner cylinder 5. . A plurality (two in this embodiment) of ring-shaped protrusions 61 are formed on the entire outer periphery of the gasket body 60, and these protrusions 61 are in close contact with the inner peripheral surface of the inner cylinder 5. By sliding while sliding, the liquid-tightness can be more reliably maintained and the slidability can be improved.
　また、ガスケット本体６０は、基端側に凹部を有し、その凹部内には、後述する投与デバイス３のプランジャ１２がガスケット６を押圧して先端方向に移動させる際に、そのプランジャ１２に当接する当接部６２が嵌入している。 Further, the gasket body 60 has a concave portion on the proximal end side, and when the plunger 12 of the administration device 3 to be described later presses the gasket 6 and moves in the distal direction, the plunger main body 60 contacts the plunger 12. The contact part 62 which contacts is inserted.
　なお、このガスケット６と内筒５と封止部９とで囲まれた空間には、液体が充填されている。そして、両頭針７の基端側針先７２が封止部９を刺通した状態で、ガスケット６が先端方向に向かって移動することにより、内筒５内の液体を両頭針７から押し出すこと、すなわち、排出することができる。 Note that the space surrounded by the gasket 6, the inner cylinder 5, and the sealing portion 9 is filled with liquid. Then, with the proximal needle tip 72 of the double-ended needle 7 penetrating the sealing portion 9, the liquid in the inner cylinder 5 is pushed out from the double-ended needle 7 by the gasket 6 moving toward the distal direction. That is, it can be discharged.
　ガスケット本体６０、封止部９の構成材料としては、特に限定されず、例えば、天然ゴム、ブチルゴム、イソプレンゴム、ブタジエンゴム、スチレン－ブタジエンゴム、シリコーンゴムのような各種ゴム材料や、ポリウレタン系、ポリエステル系、ポリアミド系、オレフィン系、スチレン系等の各種熱可塑性エラストマー、あるいはそれらの混合物等の弾性材料が挙げられる。 The material constituting the gasket body 60 and the sealing portion 9 is not particularly limited. For example, various rubber materials such as natural rubber, butyl rubber, isoprene rubber, butadiene rubber, styrene-butadiene rubber, and silicone rubber, polyurethane-based materials, Examples thereof include various thermoplastic elastomers such as polyester, polyamide, olefin, and styrene, or elastic materials such as a mixture thereof.
　また、当接部６２の構成材料としては、特に限定されず、例えば、前記外筒４の構成材料と同様のものが挙げられる。 Further, the constituent material of the contact portion 62 is not particularly limited, and examples thereof include the same constituent materials as those of the outer cylinder 4.
　包装体８は、先端側が先端壁８１で閉じられた筒状をなしている。なお、包装体８の側壁は、本実施形態では、円筒状をなしている。 The package 8 has a cylindrical shape with the tip side closed by a tip wall 81. In addition, the side wall of the package 8 has a cylindrical shape in this embodiment.
　この包装体８の内部には、液体カートリッジ本体２０が収納されている。すなわち、先端壁８１の基端側の面には、筒状をなすキャップ部８１１が、基端側に向って突出するように形成されており、このキャップ部（キャップ）８１１に、液体カートリッジ本体２０の外筒４の口部４１が嵌合している。このようにして、液体カートリッジ本体２０は、包装体８のキャップ部８１１に、着脱自在に装着され、両頭針７の先端側針先７１は、キャップ部８１１で覆われる。なお、包装体８の基端部により、液体カートリッジ２の装着の際にプランジャ１２を押圧して基端方向に移動させるプランジャ押圧部が構成される。 The liquid cartridge main body 20 is accommodated in the package 8. That is, a cap portion 811 having a cylindrical shape is formed on the surface on the proximal end side of the distal end wall 81 so as to protrude toward the proximal end side, and the liquid cartridge main body is formed on the cap portion (cap) 811. The mouth part 41 of the 20 outer cylinders 4 is fitted. In this way, the liquid cartridge main body 20 is detachably attached to the cap portion 811 of the package 8, and the distal end needle tip 71 of the double-ended needle 7 is covered with the cap portion 811. The base end portion of the package 8 constitutes a plunger pressing portion that presses the plunger 12 and moves it in the base end direction when the liquid cartridge 2 is mounted.
　このような液体カートリッジ２は、使用時に、投与デバイス３に装着される。この場合、投与デバイス３の後述するケーシング１０の開口１０１に液体カートリッジ２を基端側から挿入し、その液体カートリッジ２を投与デバイス３に装着する。以下、この装着を単に「液体カートリッジ２の装着」とも言う。 Such a liquid cartridge 2 is attached to the administration device 3 at the time of use. In this case, the liquid cartridge 2 is inserted from the proximal end side into an opening 101 of the casing 10 described later of the administration device 3, and the liquid cartridge 2 is attached to the administration device 3. Hereinafter, this mounting is also simply referred to as “mounting of the liquid cartridge 2”.
　なお、本実施形態では、液体カートリッジ２に予め液体が充填されているが、これに限らず、液体カートリッジ２に液体が充填されておらず、例えば、使用時に、液体カートリッジ２に液体が充填されるようになっていてもよい。 In the present embodiment, the liquid cartridge 2 is preliminarily filled with liquid, but this is not limiting, and the liquid cartridge 2 is not filled with liquid. For example, the liquid cartridge 2 is filled with liquid during use. It may come to be.
　次に、投与デバイス３について説明する。
　図２および図３に示すように、投与デバイス３は、液体カートリッジ２を挿入する開口１０１を先端側に有するケーシング１０と、ケーシング１０の外側に設けられた操作部材１７と、ケーシング内に設けられた筒体１１、プランジャ１２、支持部材１３、内筒押圧部材１４、一対の突出片１５およびコイルバネ（付勢手段）１６とを備えている。本実施形態では、筒体１１、プランジャ１２、支持部材１３、内筒押圧部材１４、一対の突出片１５およびコイルバネ１６は、それぞれ、全体がケーシング１０内に収納されているが、その一部が外部に突出している場合も、ケーシング１０内に収納されているものとする。 Next, the administration device 3 will be described.
As shown in FIGS. 2 and 3, the administration device 3 includes a casing 10 having an opening 101 into which the liquid cartridge 2 is inserted on the distal end side, an operation member 17 provided outside the casing 10, and a casing. A cylindrical body 11, a plunger 12, a support member 13, an inner cylinder pressing member 14, a pair of protruding pieces 15, and a coil spring (biasing means) 16. In the present embodiment, the cylinder 11, the plunger 12, the support member 13, the inner cylinder pressing member 14, the pair of protruding pieces 15, and the coil spring 16 are all housed in the casing 10, but a part of them is housed. Even when projecting to the outside, it is assumed to be accommodated in the casing 10.
　なお、ケーシング１０、操作部材１７、筒体１１、プランジャ１２、支持部材１３、内筒押圧部材１４、一対の突出片１５の構成材料としては、特に限定されず、例えば、前記外筒４の構成材料と同様のものが挙げられる。 In addition, it does not specifically limit as a constituent material of the casing 10, the operation member 17, the cylinder 11, the plunger 12, the support member 13, the inner cylinder press member 14, and a pair of protrusion piece 15, For example, the structure of the said outer cylinder 4 The thing similar to a material is mentioned.
　ケーシング１０は、使用時に把持される把持部の機能を有しており、基端側が基端壁１０２で閉じられた筒状をなしている。基端壁１０２の大部分は、本実施形態では、基端側に凸となるように湾曲し、ドーム状をなしている。また、ケーシング１０の側壁は、本実施形態では、円筒状をなしている。 The casing 10 has a function of a gripping part that is gripped during use, and has a cylindrical shape in which a base end side is closed by a base end wall 102. In the present embodiment, most of the proximal end wall 102 is curved so as to be convex toward the proximal end, and has a dome shape. Further, the side wall of the casing 10 has a cylindrical shape in the present embodiment.
　ケーシング１０の基端壁１０２の基端側の面には、一対の突出片１５が、先端側に向って突出するように形成されている。各突出片１５は、ケーシング１０中心軸を介して対向するように配置されている。各突出片１５の先端部には、突起（第３の係合部）１５１が形成されている。 A pair of protruding pieces 15 are formed on the surface of the proximal end wall 102 of the casing 10 so as to protrude toward the distal end side. Each protrusion piece 15 is arrange | positioned so that it may oppose through the casing 10 central axis. A protrusion (third engaging portion) 151 is formed at the tip of each protruding piece 15.
　また、ケーシング１０内であって、各突出片１５の先端側には、基端側が基端壁１１１で閉じられた筒状をなす筒体１１が固定されている。筒体１１は、その中心軸とケーシング１０の中心軸とが一致するように配置されている。また、基端壁１１１の中央部には、開口１１２が形成されており、この開口１２を後述するプランジャ１２が通過し得るようになっている。 Further, in the casing 10, a cylindrical body 11 having a cylindrical shape whose base end side is closed by a base end wall 111 is fixed to the distal end side of each protruding piece 15. The cylinder 11 is arranged so that the central axis thereof coincides with the central axis of the casing 10. Further, an opening 112 is formed in the central portion of the base end wall 111, and a plunger 12 described later can pass through the opening 12.
　また、ケーシング１０内、すなわち、筒体１１内には、プランジャ１２を軸方向に移動可能に支持するとともに、液体カートリッジ２の装着の際、その液体カートリッジ２の突起４３と係合する支持部材１３が固定されている。 Further, in the casing 10, that is, in the cylindrical body 11, the plunger 12 is supported so as to be movable in the axial direction, and the support member 13 that engages with the protrusion 43 of the liquid cartridge 2 when the liquid cartridge 2 is mounted. Is fixed.
　支持部材１３は、筒体１１の基端壁１１１に固定された一対の基部１３０と、各基部１３０から２つずつ軸方向に突出するように形成された４つの支柱１３１と、支柱１３１の先端側に位置し、軸方向に延びる長手形状の一対の腕部１３２と、各支柱１３１と各腕部１３２とを連結する一対の連結部１３３とを有している。なお、２つの支柱１３１と１つの腕部１３２とが連結部１３３で連結されている。また一対の腕部１３２は、プランジャ１２を介して互いに対向するように配置されている。 The support member 13 includes a pair of base portions 130 fixed to the base end wall 111 of the cylindrical body 11, four struts 131 formed so as to protrude from the base portions 130 two in the axial direction, and the distal ends of the struts 131. It has a pair of long arm parts 132 which are located on the side and extend in the axial direction, and a pair of connecting parts 133 which connect each support 131 and each arm part 132. Two struts 131 and one arm part 132 are connected by a connecting part 133. The pair of arm portions 132 are disposed so as to oppose each other via the plunger 12.
　各腕部１３２の先端部には、それぞれ、突起（第２の係合部）１３４が形成されている。液体カートリッジ２の装着の際は、液体カートリッジ２の各突起４３と各突起１３４とが、その突起１３４が突起４３の外側になるように係合する。これにより、支持部材１３に対する外筒４の先端方向への移動が阻止される。なお、突起１３４の内面は、その厚さが先端方向に向かって漸減する傾斜面になっている。また、前述したように、突起４３の外面も傾斜面になっているので、突起４３と突起１３４とが円滑に係合することができる。 A protrusion (second engaging portion) 134 is formed at the tip of each arm portion 132. When the liquid cartridge 2 is mounted, the protrusions 43 and the protrusions 134 of the liquid cartridge 2 are engaged so that the protrusions 134 are outside the protrusions 43. Thereby, the movement to the front-end | tip direction of the outer cylinder 4 with respect to the support member 13 is blocked | prevented. Note that the inner surface of the protrusion 134 is an inclined surface whose thickness gradually decreases in the distal direction. Further, as described above, since the outer surface of the protrusion 43 is also an inclined surface, the protrusion 43 and the protrusion 134 can smoothly engage with each other.
　プランジャ１２は、ケーシング１０の中心軸上であって、一対の基部１３０の間と、４つの支柱１３１の間に配置され、各基部１３０および各支柱１３１により、軸方向に移動可能に支持されている。 The plunger 12 is on the central axis of the casing 10 and is disposed between the pair of base portions 130 and between the four support columns 131, and is supported by the base portions 130 and the support columns 131 so as to be movable in the axial direction. Yes.
　プランジャ１２は、液体カートリッジ２の装着状態で液体投与セット１を使用する際に、ガスケット６に当接し、そのガスケット６を押圧して先端方向に移動させるものである。 When the liquid administration set 1 is used with the liquid cartridge 2 mounted, the plunger 12 abuts on the gasket 6 and presses the gasket 6 to move in the distal direction.
　このプランジャ１２は、その軸に対して側方に、かつ両側に突出する突出部１２１を有している。また、プランジャ１２の基端部には、突起１２２（第４の係合部）が形成されている。液体カートリッジ２の装着の際は、一対の突出片１５の各突起１５１と突起１２２とが、その突起１２２が突起１５１の内側になるように係合する。これにより、ケーシング１０に対するプランジャ１２の先端方向への移動が阻止される。なお、突起１２２は、先端側に円錐状の部位を有している。すなわち、突起１２２の先端側の表面は、外径が基端方向に向かって漸減する傾斜面になっている。これにより、突起１５１と突起１２２とが円滑に係合することができる。 The plunger 12 has projecting portions 121 projecting laterally and on both sides with respect to the shaft. Further, a protrusion 122 (fourth engagement portion) is formed at the proximal end portion of the plunger 12. When the liquid cartridge 2 is mounted, the protrusions 151 and the protrusions 122 of the pair of protruding pieces 15 are engaged so that the protrusions 122 are inside the protrusions 151. Thereby, the movement to the front-end | tip direction of the plunger 12 with respect to the casing 10 is blocked | prevented. The protrusion 122 has a conical portion on the tip side. That is, the surface on the distal end side of the protrusion 122 is an inclined surface whose outer diameter gradually decreases in the proximal direction. Thereby, the protrusion 151 and the protrusion 122 can engage smoothly.
　また、支持部材１３および内筒押圧部材１４の外周側であって、筒体１１の基端壁１１１とプランジャ１２の突出部１２１との間には、プランジャ１２を先端方向に付勢するコイルバネ１６が設置されている。このコイルバネ１６は、若干収縮した状態または自然状態で設置されている。 Further, on the outer peripheral side of the support member 13 and the inner cylinder pressing member 14 and between the proximal end wall 111 of the cylinder 11 and the protruding portion 121 of the plunger 12, a coil spring 16 that biases the plunger 12 in the distal direction. Is installed. The coil spring 16 is installed in a slightly contracted state or a natural state.
　液体カートリッジ２の装着の際は、投与デバイス３を液体カートリッジ２に対して先端方向に移動させると、液体カートリッジ２の包装体８の基端部により、突出部１２１が基端方向に押圧される。これにより、プランジャ１２は、コイルバネ１６の付勢力に抗して基端方向に移動し、コイルバネ１６が収縮する。そして、一対の突出片１５の各突起１５１とプランジャ１２の突起１２２とが係合し、これにより、ケーシング１０に対するプランジャ１２の先端方向への移動が阻止され、前記コイルバネ１６が収縮した状態が保持される。 When the liquid cartridge 2 is mounted, when the administration device 3 is moved in the distal direction with respect to the liquid cartridge 2, the protruding portion 121 is pressed in the proximal direction by the proximal end portion of the package 8 of the liquid cartridge 2. . As a result, the plunger 12 moves in the proximal direction against the urging force of the coil spring 16 and the coil spring 16 contracts. Then, the protrusions 151 of the pair of protruding pieces 15 and the protrusions 122 of the plunger 12 are engaged with each other, whereby the movement of the plunger 12 in the distal direction with respect to the casing 10 is prevented, and the coil spring 16 is kept contracted. Is done.
　なお、未使用状態では、プランジャ１２の突出部１２１が支持部材１３の連結部１３３に当接し、これにより、プランジャ１２の先端方向への移動が阻止される。 In the unused state, the protruding portion 121 of the plunger 12 abuts on the connecting portion 133 of the support member 13, thereby preventing the plunger 12 from moving in the distal direction.
　また、ケーシング１０内、すなわち、筒体１１内には、液体カートリッジ２の装着の際に、液体カートリッジ２の内筒５を押圧して先端方向に移動させる内筒押圧部材１４が固定されている。 Also, an inner cylinder pressing member 14 that presses the inner cylinder 5 of the liquid cartridge 2 and moves it in the distal direction when the liquid cartridge 2 is mounted is fixed in the casing 10, that is, in the cylinder 11. .
　内筒押圧部材１４は、プランジャ１２を介して対向するように設けられた、長手形状をなす一対の支持部１４１と、各支持部１４１の基端部同士を連結するように設けられ、長手形状をなす内筒押圧部１４２とを有している。内筒押圧部１４２は、内筒５の基端部を押圧する部位であり、プランジャ１２の外周に配置されている。すなわち、内筒押圧部１４２の中央部には、開口１４３が形成され、プランジャ１２は、その開口を挿通している。 The inner cylinder pressing member 14 is provided so as to connect a pair of support portions 141 having a longitudinal shape, which are provided so as to face each other via the plunger 12, and the base end portions of the respective support portions 141. And an inner cylinder pressing portion 142. The inner cylinder pressing portion 142 is a portion that presses the proximal end portion of the inner cylinder 5, and is disposed on the outer periphery of the plunger 12. That is, an opening 143 is formed in the central portion of the inner cylinder pressing portion 142, and the plunger 12 is inserted through the opening.
　また、ケーシング１０の底板１０２の一部の表面は、平面になっており、その底板１０２の平面の部位に、操作部材１７が図３中左右方向に移動可能に設置されている。この操作部材１７は、プランジャ１２の突起１２２と一対の突出片１５の突起１５１との係合を解除する操作を行うものである。操作部材１７は、基部１７１と、基部１７１に固定された板状をなす指当部１７２と、指当部１７２に形成された板状をなす突出部１７３とを有している。突出部１７３は、指当部１７２から、指当部１７２に対して垂直な方向に突出している。そして、突出部１７３の幅Ｗは、図３中右側から左側に向って漸増している。 Further, a part of the surface of the bottom plate 102 of the casing 10 is a flat surface, and the operation member 17 is installed on the flat portion of the bottom plate 102 so as to be movable in the left-right direction in FIG. The operation member 17 performs an operation of releasing the engagement between the protrusion 122 of the plunger 12 and the protrusion 151 of the pair of protruding pieces 15. The operation member 17 includes a base 171, a finger-like portion 172 having a plate shape fixed to the base portion 171, and a protruding portion 173 having a plate shape formed in the finger-holding portion 172. The protruding portion 173 protrudes from the finger holding portion 172 in a direction perpendicular to the finger holding portion 172. Then, the width W of the protrusion 173 gradually increases from the right side to the left side in FIG.
　この操作部材１７は、一対の突出片１５の間に突出部１７３が位置するように配置されている。また、未使用状態では、操作部材１７は、一対の突出片１５に当接していない。そして、未使用状態から操作部材１７を図３中右側に移動させると、突出部１７３が一対の突出片１５に当接し、その突出部１７３により一対の突出片１５の間の間隔が広がるようになっている。これにより、プランジャ１２の突起１２２と一対の突出片１５の突起１５１との係合が解除される（図１０、図１１参照）。 The operating member 17 is arranged so that the protruding portion 173 is positioned between the pair of protruding pieces 15. In the unused state, the operation member 17 is not in contact with the pair of protruding pieces 15. When the operating member 17 is moved from the unused state to the right side in FIG. 3, the projecting portions 173 abut against the pair of projecting pieces 15, and the projecting portions 173 widen the distance between the pair of projecting pieces 15. It has become. As a result, the engagement between the protrusion 122 of the plunger 12 and the protrusion 151 of the pair of protruding pieces 15 is released (see FIGS. 10 and 11).
　次に、液体投与セット１の使用方法と、その使用時の作動状態とについて、図１～図１３を参照しつつ説明する。 Next, a method of using the liquid administration set 1 and an operating state at the time of use will be described with reference to FIGS.
　［１］　図１～図３に示す未使用状態の液体カートリッジ２および投与デバイス３で構成された液体投与セット１を用意する。この未使用状態の液体投与セット１では、液体カートリッジ２の内筒５は、図１および図５に示すように、第１の位置に位置し、両頭針７の基端側針先７２が封止部９を刺通しておらず、内筒５の基端部は、外筒４の基端部から基端方向に突出している。 [1] A liquid dosing set 1 composed of an unused liquid cartridge 2 and a dosing device 3 shown in FIGS. 1 to 3 is prepared. In this unused liquid administration set 1, the inner cylinder 5 of the liquid cartridge 2 is located at the first position as shown in FIGS. 1 and 5, and the proximal end needle tip 72 of the double-ended needle 7 is sealed. The stop portion 9 is not pierced, and the proximal end portion of the inner cylinder 5 protrudes from the proximal end portion of the outer tube 4 in the proximal direction.
　［２］　次に、図４および図５に示すように、ケーシング１０を把持し、投与デバイス３の開口１０１に液体カートリッジ２を基端側から挿入する。この際、投与デバイス３側の腕部１３２の突起１３４と、液体カートリッジ２側の腕部４２の突起４３とが対応するように、位置合わせを行う。そして、投与デバイス３を先端方向に押圧し、その投与デバイス３を液体カートリッジ２に対して先端方向に移動させ、液体カートリッジ２を投与デバイス３に装着する。なお、この際、下記の動作が生じ、液体カートリッジ２が投与デバイス３に装着される。 [2] Next, as shown in FIGS. 4 and 5, the casing 10 is gripped, and the liquid cartridge 2 is inserted into the opening 101 of the administration device 3 from the proximal end side. At this time, the alignment is performed so that the projection 134 of the arm portion 132 on the administration device 3 side corresponds to the projection 43 of the arm portion 42 on the liquid cartridge 2 side. Then, the administration device 3 is pressed in the distal direction, the administration device 3 is moved in the distal direction with respect to the liquid cartridge 2, and the liquid cartridge 2 is attached to the administration device 3. At this time, the following operation occurs, and the liquid cartridge 2 is attached to the administration device 3.
　すなわち、投与デバイス３の移動により、図４および図５に示すように、液体カートリッジ２の包装体８の基端部に、投与デバイス３のプランジャ１２の突出部１２１が当接し、その包装体８の基端部により、突出部１２１が基端方向に押圧される。これによって、図６および図７に示すように、プランジャ１２は、コイルバネ１６の付勢力に抗して基端方向に移動し、コイルバネ１６が収縮する。 That is, due to the movement of the administration device 3, as shown in FIGS. 4 and 5, the protruding portion 121 of the plunger 12 of the administration device 3 comes into contact with the proximal end portion of the packaging body 8 of the liquid cartridge 2, and the packaging body 8. The protruding portion 121 is pressed in the proximal direction by the proximal end portion. 6 and 7, the plunger 12 moves in the proximal direction against the biasing force of the coil spring 16, and the coil spring 16 contracts.
　また、前記投与デバイス３の移動により、図８に示すように、液体カートリッジ２の各突起４３と投与デバイス３の各突起１３４とが係合する。これにより、ケーシング１０、すなわち、支持部材１３に対する外筒４の先端方向への移動が阻止される。 Further, as shown in FIG. 8, the movement of the administration device 3 causes the projections 43 of the liquid cartridge 2 and the projections 134 of the administration device 3 to engage with each other. Thereby, the movement to the front-end | tip direction of the outer cylinder 4 with respect to the casing 10, ie, the support member 13, is blocked | prevented.
　また、前記投与デバイス３の移動により、図６に示すように、液体カートリッジ２の内筒５の基端部に、投与デバイス３の内筒押圧部材１４の内筒押圧部１４２が当接し、その内筒押圧部１４２により、内筒５が先端方向に押圧される。これによって、図７および図８に示すように、内筒５が先端方向に移動、すなわち、第２の位置に移動し、両頭針７の基端側針先７２が封止部９を刺通し、両頭針７の内腔と内筒５とが連通する。 Further, as shown in FIG. 6, the movement of the administration device 3 causes the inner cylinder pressing portion 142 of the inner cylinder pressing member 14 of the administration device 3 to come into contact with the proximal end portion of the inner cylinder 5 of the liquid cartridge 2. The inner cylinder pressing portion 142 presses the inner cylinder 5 in the distal direction. As a result, as shown in FIGS. 7 and 8, the inner cylinder 5 moves in the distal direction, that is, moves to the second position, and the proximal needle tip 72 of the double-ended needle 7 penetrates the sealing portion 9, The lumen of the double-ended needle 7 and the inner cylinder 5 communicate with each other.
　一方、図８に示すように、液体カートリッジ２のプランジャ１２の突起１２２は、投与デバイス３の一対の突出片１５の突起１５１の間を通過し、突起１５１よりも基端側に移動し、一旦、その突起１２２と突起１５１との間に間隙が形成される。そして、投与デバイス３を先端方向に押圧することを中止すると、コイルバネ１６の付勢力により、プランジャ１２が先端方向に移動し、各突起１５１と突起１２２とが係合し、これにより、ケーシング１０に対するプランジャ１２の先端方向への移動が阻止され、コイルバネ１６が収縮した状態が保持される（図９参照）。 On the other hand, as shown in FIG. 8, the protrusion 122 of the plunger 12 of the liquid cartridge 2 passes between the protrusions 151 of the pair of protruding pieces 15 of the administration device 3, moves to the proximal side of the protrusion 151, and A gap is formed between the protrusion 122 and the protrusion 151. When the pressing of the administration device 3 in the distal direction is stopped, the plunger 12 moves in the distal direction by the urging force of the coil spring 16, and the projections 151 and the projections 122 are engaged with each other. The movement of the plunger 12 in the distal direction is prevented, and the coil spring 16 is kept contracted (see FIG. 9).
　［３］　次に、図９に示すように、包装体８を先端方向に引っ張り、その包装体８を液体カートリッジ本体２０から取り外す。以上で、液体カートリッジ２の装着が完了する。この液体カートリッジ２が投与デバイス３に装着された状態では、ケーシングの先端から、両頭針７が先端方向に突出する。 [3] Next, as shown in FIG. 9, the package 8 is pulled in the distal direction, and the package 8 is removed from the liquid cartridge body 20. Thus, the mounting of the liquid cartridge 2 is completed. In a state where the liquid cartridge 2 is mounted on the administration device 3, the double-ended needle 7 projects from the distal end of the casing in the distal direction.
　［４］　次に、両頭針７を生体に穿刺し、図１０および図１１に示すように、操作部材１７を図１０中右側に移動させる。 [4] Next, the double-ended needle 7 is punctured into the living body, and the operation member 17 is moved to the right side in FIG. 10 as shown in FIGS.
　これにより、操作部材１７の突出部１７３が一対の突出片１５に当接し、その突出部１７３により一対の突出片１５の間の間隔が広がり、プランジャ１２の突起１２２と一対の突出片１５の突起１５１との係合が解除される。 As a result, the projecting portions 173 of the operating member 17 abut against the pair of projecting pieces 15, and the spacing between the pair of projecting pieces 15 is widened by the projecting portions 173, so The engagement with 151 is released.
　これによって、図１２に示すように、コイルバネ１６の付勢力により、プランジャ１２が先端方向に移動し、そのプランジャ１２とともにガスケット６が先端方向に押圧され、ガスケット６が内筒５内を先端方向に向かって摺動する。これにより、内筒５内の液体が、両頭針７の先端側針先７１から排出され、生体に投与される。 Accordingly, as shown in FIG. 12, the urging force of the coil spring 16 moves the plunger 12 in the distal direction, and the gasket 6 is pressed in the distal direction together with the plunger 12, and the gasket 6 moves in the inner cylinder 5 in the distal direction. Slide towards. Thereby, the liquid in the inner cylinder 5 is discharged | emitted from the front end side needle tip 71 of the double-ended needle 7, and is administered to a biological body.
　［５］　次に、液体カートリッジ２を投与デバイス３から取り外し、廃棄する。
　以上説明したように、この液体投与セット１によれば、ケーシング１０の開口１０１に液体カートリッジ２を基端側から挿入し、投与デバイス３を液体カートリッジ２に対して先端方向に移動させるだけで、液体カートリッジ２を投与デバイス３に装着することができる。すなわち、液体投与セット１を組み立てることができる。これにより、その組み立てを容易かつ迅速に行うことができる。 [5] Next, the liquid cartridge 2 is removed from the administration device 3 and discarded.
As described above, according to this liquid administration set 1, just by inserting the liquid cartridge 2 into the opening 101 of the casing 10 from the proximal end side and moving the administration device 3 in the distal direction with respect to the liquid cartridge 2, The liquid cartridge 2 can be attached to the administration device 3. That is, the liquid administration set 1 can be assembled. Thereby, the assembly can be performed easily and rapidly.
　また、使用後に破棄される部材は、液体カートリッジ２の１部材のみであるので、従来に比べて、その使用後に破棄される部材を削減することができる。 Further, since only one member of the liquid cartridge 2 is discarded after use, the number of members discarded after use can be reduced as compared with the conventional case.
　なお、液体カートリッジ２の装着の際の投与デバイス３側の腕部１３２の突起１３４と、液体カートリッジ２側の腕部４２の突起４３とを位置決めする位置決め手段が設けられていてもよい。この位置決め手段は、例えば、液体カートリッジ２と投与デバイス３との一方に設けられた溝と、他方に設けられた突起またはリブとで構成することができる。 Note that positioning means for positioning the projection 134 of the arm portion 132 on the administration device 3 side and the projection 43 of the arm portion 42 on the liquid cartridge 2 side when the liquid cartridge 2 is mounted may be provided. This positioning means can be constituted by, for example, a groove provided in one of the liquid cartridge 2 and the administration device 3 and a protrusion or rib provided in the other.
　また、本実施形態では、投与デバイス３側の突起１３４の数は、２つであるが、これに限らず、３つ以上でもよい。 In the present embodiment, the number of the protrusions 134 on the administration device 3 side is two, but is not limited thereto, and may be three or more.
　また、本実施形態では、液体カートリッジ２側の突起４３の数は、２つであるが、これに限らず、３つ以上でもよい。 In the present embodiment, the number of the protrusions 43 on the liquid cartridge 2 side is two, but the number is not limited thereto, and may be three or more.
　また、本実施形態では、投与デバイス３側の突起１３４の数と、液体カートリッジ２側の突起４３の数とが同一であるが、異なっていてもよい。 In this embodiment, the number of protrusions 134 on the administration device 3 side and the number of protrusions 43 on the liquid cartridge 2 side are the same, but they may be different.
　また、投与デバイス３側の突起１３４は、外筒４の一周に亘って形成されていてもよい。すなわち、第１の係合部は、外筒４の一周に亘って形成されたリブであってもよい。 Further, the protrusion 134 on the administration device 3 side may be formed over the entire circumference of the outer cylinder 4. That is, the first engaging portion may be a rib formed over one circumference of the outer cylinder 4.
　また、前記実施形態では、第１の係合部は、外筒に設けられているが、本発明では、これに限らず、第１の係合部は、例えば、内筒に設けられていてもよい。 Moreover, in the said embodiment, although the 1st engaging part is provided in the outer cylinder, in this invention, not only this but the 1st engaging part is provided in the inner cylinder, for example. Also good.
　＜第２実施形態＞
　図１３は、本発明の液体投与セットの第２実施形態における第２の組立体である投与デバイスを示す斜視図である。 <Second Embodiment>
FIG. 13: is a perspective view which shows the administration device which is the 2nd assembly in 2nd Embodiment of the liquid administration set of this invention.
　なお、以下では、図１３中の左側を上側を「基端（後端）」、下側を「先端」、上下方向を「軸方向」または「長手方向」として説明を行う。 In the following description, the left side in FIG. 13 is described as “upper end (rear end)” on the upper side, “front end” on the lower side, and “axial direction” or “longitudinal direction” on the vertical direction.
　以下、第２実施形態について、前述した第１実施形態との相違点を中心に説明し、同様の事項については、その説明を省略する。 Hereinafter, the second embodiment will be described with a focus on differences from the first embodiment described above, and description of similar matters will be omitted.
　第２実施形態は、投与デバイス３の構成が異なること以外は前記第１実施形態と同様である。 The second embodiment is the same as the first embodiment except that the configuration of the administration device 3 is different.
　図１３に示すように、第２実施形態の液体投与セット１では、投与デバイス３は、手動でプランジャ１２を移動操作するように構成されている。 As shown in FIG. 13, in the liquid administration set 1 of the second embodiment, the administration device 3 is configured to manually move the plunger 12.
　すなわち、投与デバイス３は、ケーシング１０と、ケーシング内に設けられたプランジャ１２、一対の腕部１３２および内筒押圧部材１４とを備えている。プランジャ１２の基端部には、円盤状のフランジ１２３が形成されている。なお、各部の形状は、第１実施形態と異なるが、機能は、同様であるので、その説明は省略する。
　この液体投与セット１によれば、前述した第１実施形態と同様の効果が得られる。 That is, the administration device 3 includes a casing 10, a plunger 12 provided in the casing, a pair of arm portions 132, and an inner cylinder pressing member 14. A disc-shaped flange 123 is formed at the base end portion of the plunger 12. In addition, although the shape of each part differs from 1st Embodiment, since the function is the same, the description is abbreviate | omitted.
According to this liquid administration set 1, the same effect as that of the first embodiment described above can be obtained.
　以上、本発明の液体投与セットを、図示の実施形態に基づいて説明したが、本発明はこれに限定されるものではなく、各部の構成は、同様の機能を有する任意の構成のものに置換することができる。また、本発明に、他の任意の構成物や、工程が付加されていてもよい。 The liquid administration set of the present invention has been described based on the illustrated embodiment. However, the present invention is not limited to this, and the configuration of each part is replaced with an arbitrary configuration having the same function. can do. Moreover, other arbitrary structures and processes may be added to the present invention.
　また、本発明は、前記各実施形態のうちの、任意の２以上の構成（特徴）を組み合わせたものであってもよい。 Further, the present invention may be a combination of any two or more configurations (features) of the above embodiments.
　本発明の液体投与セットは、液体が充填される第１の組立体と、使用時に、該第１の組立体が装着され、その装着状態で、前記第１の組立体から前記液体を排出する操作を行う第２の組立体とを備える液体投与セットであって、
　前記第１の組立体は、筒状をなす外筒と、
　前記外筒の先端部に装着され、先端側に先端側針先を有し、基端側に基端側針先を有する両頭針と、
　筒状をなし、先端側に前記液体を排出する口部を有し、前記外筒内で該外筒の軸方向に沿って移動し得る内筒と、
　前記内筒内で該内筒の軸方向に沿って移動し得るガスケットと、
　前記内筒の前記口部に装着され、前記内筒と前記ガスケットとで囲まれる空間を封止し、前記両頭針の前記基端側針先が刺通し得る封止部と、
　前記外筒または前記内筒に設けられた第１の係合部とを備え、前記内筒と前記ガスケットと前記封止部とで囲まれた空間に前記液体が充填される第１の組立体本体と、
　前記第１の組立体本体の前記両頭針の少なくとも前記先端側針先を覆うキャップとを具備し、
　前記第２の組立体は、前記第１の組立体を挿入する開口を先端側に有するケーシングと、
　前記ケーシングに対して、軸方向に移動可能に設置され、前記装着状態で当該液体投与セットを使用する際に、前記ガスケットを押圧して先端方向に移動させるプランジャと、
　前記ケーシング内に支持され、前記開口に前記第１の組立体を基端側から挿入して前記第１の組立体を前記第２の組立体に装着する際に、前記内筒を押圧して先端方向に移動させる内筒押圧部と、
　前記ケーシング内に支持され、前記装着の際に、前記第１の係合部と係合し得る第２の係合部と具備し、
　前記内筒は、前記外筒に対して、前記両頭針の前記基端側針先が前記封止部を刺通していない第１の位置から、前記基端側針先が前記封止部を刺通して、前記両頭針の内腔と前記内筒とが連通する第２の位置に移動可能であり、
　前記装着前は、前記内筒は、前記第１の位置に位置し、
　前記装着の際、前記第２の組立体を前記第１の組立体に対して先端方向に移動させると、前記内筒押圧部により、前記内筒が押圧されて第２の位置に移動し、前記両頭針の前記基端側針先が前記封止部を刺通して、前記両頭針の内腔と前記内筒とが連通し、前記第１の係合部と前記第２の係合部とが係合し、この係合により前記ケーシングに対して前記外筒および前記内筒が先端方向に移動することが阻止され、前記装着状態となるよう構成されていることを特徴とする。
　本発明によれば、ケーシングの開口に第１の組立体を基端側から挿入して第１の組立体を第２の組立体に装着することにより、使用可能な状態とすること、すなわち、組み立てることができる。これにより、その組み立てを容易かつ迅速に行うことができる。
　また、従来に比べて、使用後に破棄される部材を削減することができる。
　したがって産業上の利用可能性を有する。 The liquid dosing set according to the present invention includes a first assembly that is filled with a liquid, and the first assembly is mounted during use, and the liquid is discharged from the first assembly in the mounted state. A liquid dosing set comprising a second assembly for operation,
The first assembly includes a cylindrical outer cylinder,
A double-ended needle that is attached to the distal end of the outer cylinder, has a distal needle tip on the distal side, and has a proximal needle tip on the proximal side;
An inner cylinder that has a cylindrical shape, has a mouth for discharging the liquid on the tip side, and can move along the axial direction of the outer cylinder in the outer cylinder;
A gasket capable of moving along the axial direction of the inner cylinder in the inner cylinder;
A sealing portion that is attached to the mouth portion of the inner cylinder, seals a space surrounded by the inner cylinder and the gasket, and allows the proximal end needle tip of the double-ended needle to be pierced;
A first assembly that includes a first engagement portion provided on the outer cylinder or the inner cylinder, and in which a space surrounded by the inner cylinder, the gasket, and the sealing portion is filled with the liquid. The body,
A cap that covers at least the tip side needle tip of the double-ended needle of the first assembly body;
The second assembly includes a casing having an opening for inserting the first assembly on a distal end side;
A plunger that is installed so as to be movable in the axial direction with respect to the casing, and when the liquid administration set is used in the mounted state, a plunger that presses the gasket and moves it in a distal direction.
When the first assembly is inserted into the opening from the proximal end side and the first assembly is mounted on the second assembly, the inner cylinder is pressed. An inner cylinder pressing portion that moves in the distal direction,
A second engagement portion supported in the casing and capable of engaging with the first engagement portion at the time of mounting;
In the inner cylinder, the proximal needle tip penetrates the sealing portion from a first position where the proximal needle tip of the double-ended needle does not penetrate the sealing portion with respect to the outer cylinder. And can be moved to a second position where the lumen of the double-ended needle and the inner cylinder communicate with each other,
Before the mounting, the inner cylinder is located at the first position,
During the mounting, when the second assembly is moved in the distal direction with respect to the first assembly, the inner cylinder is pressed by the inner cylinder pressing portion and moved to the second position, The proximal end needle tip of the double-ended needle pierces the sealing portion, the lumen of the double-ended needle communicates with the inner cylinder, the first engaging portion and the second engaging portion; Is engaged, and the engagement prevents the outer cylinder and the inner cylinder from moving in the distal direction with respect to the casing, and the mounting state is established.
According to the present invention, the first assembly is inserted into the opening of the casing from the proximal end side, and the first assembly is attached to the second assembly, thereby enabling the use, that is, Can be assembled. Thereby, the assembly can be performed easily and rapidly.
Moreover, the member discarded after use can be reduced compared with the past.
Therefore, it has industrial applicability.
　１　　　　　　　液体投与セット
　２　　　　　　　液体カートリッジ
　２０　　　　　　液体カートリッジ本体
　３　　　　　　　投与デバイス
　４　　　　　　　外筒
　４１　　　　　　口部
　４２　　　　　　腕部
　４３　　　　　　突起
　５　　　　　　　内筒
　５１　　　　　　口部
　６　　　　　　　ガスケット
　６０　　　　　　ガスケット本体
　６１　　　　　　突部
　６２　　　　　　当接部
　７　　　　　　　両頭針
　７１　　　　　　先端側針先
　７２　　　　　　基端側針先
　８　　　　　　　包装体
　８１　　　　　　先端壁
　８１１　　　　　キャップ部
　９　　　　　　　封止部
　１０　　　　　　ケーシング
　１０１　　　　　開口
　１０２　　　　　基端壁
　１１　　　　　　筒体
　１１１　　　　　基端壁
　１１２　　　　　開口
　１２　　　　　　プランジャ
　１２１　　　　　突出部
　１２２　　　　　突起
　１２３　　　　　フランジ
　１３　　　　　　支持部材
　１３０　　　　　基部
　１３１　　　　　支柱
　１３２　　　　　腕部
　１３３　　　　　連結部
　１３４　　　　　突起
　１４　　　　　　内筒押圧部材
　１４１　　　　　支持部
　１４２　　　　　内筒押圧部
　１４３　　　　　開口
　１５　　　　　　突出片
　１５１　　　　　突起
　１６　　　　　　コイルバネ
　１７　　　　　　操作部材
　１７１　　　　　基部
　１７２　　　　　指当部
　１７３　　　　　突出部 DESCRIPTION OF SYMBOLS 1 Liquid dosing set 2 Liquid cartridge 20 Liquid cartridge main body 3 Dosing device 4 Outer cylinder 41 Mouth part 42 Arm part 43 Projection 5 Inner cylinder 51 Mouth part 6 Gasket 60 Gasket main body 61 Projection part 62 Contact part 7 Double-headed needle 71 Tip side needle Point 72 Base end side needle tip 8 Packaging body 81 Tip wall 811 Cap portion 9 Sealing portion 10 Casing 101 Opening 102 Base end wall 11 Cylindrical body 111 Base end wall 112 Opening 12 Plunger 121 Protruding portion 122 Protruding 123 Flange 13 Support member 130 Base portion 131 Support column 132 Arm portion 133 Connecting portion 134 Projection 14 Inner cylinder pressing member 141 Support portion 142 Inner cylinder pressing portion 143 Opening 15 Protruding piece 151 Protrusion 16 Coil spring 17 Operation member 171 Base 172 Finger holding part 173 Protruding part

Claims (12)

  1. 　液体が充填される第１の組立体と、使用時に、該第１の組立体が装着され、その装着状態で、前記第１の組立体から前記液体を排出する操作を行う第２の組立体とを備える液体投与セットであって、
    　前記第１の組立体は、筒状をなす外筒と、
    　前記外筒の先端部に装着され、先端側に先端側針先を有し、基端側に基端側針先を有する両頭針と、
    　筒状をなし、先端側に前記液体を排出する口部を有し、前記外筒内で該外筒の軸方向に沿って移動し得る内筒と、
    　前記内筒内で該内筒の軸方向に沿って移動し得るガスケットと、
    　前記内筒の前記口部に装着され、前記内筒と前記ガスケットとで囲まれる空間を封止し、前記両頭針の前記基端側針先が刺通し得る封止部と、
    　前記外筒または前記内筒に設けられた第１の係合部とを備え、前記内筒と前記ガスケットと前記封止部とで囲まれた空間に前記液体が充填される第１の組立体本体と、
    　前記第１の組立体本体の前記両頭針の少なくとも前記先端側針先を覆うキャップとを具備し、
    　前記第２の組立体は、前記第１の組立体を挿入する開口を先端側に有するケーシングと、
    　前記ケーシングに対して、軸方向に移動可能に設置され、前記装着状態で当該液体投与セットを使用する際に、前記ガスケットを押圧して先端方向に移動させるプランジャと、
    　前記ケーシング内に支持され、前記開口に前記第１の組立体を基端側から挿入して前記第１の組立体を前記第２の組立体に装着する際に、前記内筒を押圧して先端方向に移動させる内筒押圧部と、
    　前記ケーシング内に支持され、前記装着の際に、前記第１の係合部と係合し得る第２の係合部と具備し、
    　前記内筒は、前記外筒に対して、前記両頭針の前記基端側針先が前記封止部を刺通していない第１の位置から、前記基端側針先が前記封止部を刺通して、前記両頭針の内腔と前記内筒とが連通する第２の位置に移動可能であり、
    　前記装着前は、前記内筒は、前記第１の位置に位置し、
    　前記装着の際、前記第２の組立体を前記第１の組立体に対して先端方向に移動させると、前記内筒押圧部により、前記内筒が押圧されて第２の位置に移動し、前記両頭針の前記基端側針先が前記封止部を刺通して、前記両頭針の内腔と前記内筒とが連通し、前記第１の係合部と前記第２の係合部とが係合し、この係合により前記ケーシングに対して前記外筒および前記内筒が先端方向に移動することが阻止され、前記装着状態となるよう構成されていることを特徴とする液体投与セット。     A first assembly that is filled with a liquid, and a second assembly that, when in use, is mounted with the first assembly, and in the mounted state, discharges the liquid from the first assembly. A liquid dosing set comprising:
    The first assembly includes a cylindrical outer cylinder,
    A double-ended needle that is attached to the distal end of the outer cylinder, has a distal needle tip on the distal side, and has a proximal needle tip on the proximal side;
    An inner cylinder that has a cylindrical shape, has a mouth for discharging the liquid on the tip side, and can move along the axial direction of the outer cylinder in the outer cylinder;
    A gasket capable of moving along the axial direction of the inner cylinder in the inner cylinder;
    A sealing portion that is attached to the mouth portion of the inner cylinder, seals a space surrounded by the inner cylinder and the gasket, and allows the proximal end needle tip of the double-ended needle to be pierced;
    A first assembly that includes a first engagement portion provided on the outer cylinder or the inner cylinder, and in which a space surrounded by the inner cylinder, the gasket, and the sealing portion is filled with the liquid. The body,
    A cap that covers at least the tip side needle tip of the double-ended needle of the first assembly body;
    The second assembly includes a casing having an opening for inserting the first assembly on a distal end side;
    A plunger that is installed so as to be movable in the axial direction with respect to the casing, and when the liquid administration set is used in the mounted state, a plunger that presses the gasket and moves it in a distal direction.
    When the first assembly is inserted into the opening from the proximal end side and the first assembly is mounted on the second assembly, the inner cylinder is pressed. An inner cylinder pressing portion that moves in the distal direction,
    A second engagement portion supported in the casing and capable of engaging with the first engagement portion at the time of mounting;
    In the inner cylinder, the proximal needle tip penetrates the sealing portion from a first position where the proximal needle tip of the double-ended needle does not penetrate the sealing portion with respect to the outer cylinder. And can be moved to a second position where the lumen of the double-ended needle and the inner cylinder communicate with each other,
    Before the mounting, the inner cylinder is located at the first position,
    At the time of mounting, when the second assembly is moved in the distal direction relative to the first assembly, the inner cylinder is pressed by the inner cylinder pressing portion and moved to the second position, The proximal end needle tip of the double-ended needle pierces the sealing portion, the lumen of the double-ended needle communicates with the inner cylinder, the first engaging portion and the second engaging portion; Is engaged, and the engagement prevents the outer cylinder and the inner cylinder from moving in the distal direction with respect to the casing, and the liquid administration set is configured to be in the mounted state. .
  2. 　前記第２の組立体は、前記プランジャを先端方向に付勢する付勢手段を有し、
    　前記装着状態で当該液体投与セットを使用する際、前記付勢手段の付勢力により前記プランジャが前記ガスケットとともに先端方向に移動し、前記両頭針から前記液体が排出されるよう構成されている請求項１に記載の液体投与セット。     The second assembly includes a biasing unit that biases the plunger in a distal direction.
    When the liquid administration set is used in the mounted state, the plunger is moved in the distal direction together with the gasket by the urging force of the urging means, and the liquid is discharged from the double-ended needle. The liquid administration set according to 1.
  3. 　前記第１の組立体は、前記装着の際に、前記プランジャを押圧して基端方向に移動させるプランジャ押圧部を有し、
    　前記第２の組立体は、前記ケーシング内に支持された第３の係合部を有し、
    　前記プランジャは、前記装着の際に、前記第３の係合部と係合し得る第４の係合部を有し、
    　前記装着の際、前記第２の組立体を前記第１の組立体に対して先端方向に移動させると、前記付勢手段の付勢力に抗して、前記プランジャ押圧部により、前記プランジャが押圧されて基端方向に移動し、前記第３の係合部と前記第４の係合部とが係合し、この係合により前記ケーシングに対して前記プランジャが先端方向に移動することが阻止されるよう構成されている請求項２に記載の液体投与セット。     The first assembly has a plunger pressing portion that presses the plunger to move in the proximal direction during the mounting,
    The second assembly has a third engagement portion supported in the casing,
    The plunger has a fourth engagement portion that can be engaged with the third engagement portion during the mounting,
    When the second assembly is moved in the distal direction relative to the first assembly during the mounting, the plunger is pressed by the plunger pressing portion against the urging force of the urging means. Is moved in the proximal direction, and the third engagement portion and the fourth engagement portion are engaged, and the engagement prevents the plunger from moving in the distal direction with respect to the casing. 3. A liquid dosing set according to claim 2 configured to be configured.
  4. 　前記ケーシングには、前記第３の係合部と前記第４の係合部との係合を解除する操作を行う操作部材が設けられている請求項３に記載の液体投与セット。 4. The liquid administration set according to claim 3, wherein the casing is provided with an operation member that performs an operation of releasing the engagement between the third engagement portion and the fourth engagement portion.
  5. 　前記第１の組立体は、先端側が先端壁で閉じられた筒状をなし、その内部に前記第１の組立体本体を収納する包装体を有し、
    　前記キャップは、前記先端壁に形成されており、
    　前記包装体の基端部が、前記プランジャ押圧部を構成している請求項３または４に記載の液体投与セット。     The first assembly has a cylindrical shape whose front end side is closed by a front end wall, and has a packaging body that houses the first assembly main body therein,
    The cap is formed on the tip wall;
    The liquid administration set according to claim 3 or 4, wherein a base end portion of the package constitutes the plunger pressing portion.
  6. 　前記プランジャは、その軸に対して側方に突出する突出部を有し、
    　前記装着の際、前記第２の組立体を前記第１の組立体に対して先端方向に移動させると、前記プランジャ押圧部により、前記突出部が押圧されるよう構成されている請求項３ないし５のいずれか１項に記載の液体投与セット。     The plunger has a protrusion protruding laterally with respect to its axis;
    4. The structure according to claim 3, wherein the protrusion is pressed by the plunger pressing portion when the second assembly is moved in the distal direction relative to the first assembly during the mounting. The liquid administration set according to any one of 5.
  7. 　前記ケーシングは、基端側が基端壁で閉じられた筒状をなし、
    　前記第３の係合部は、前記基端壁に形成されている請求項３ないし６のいずれか１項に記載の液体投与セット。     The casing has a cylindrical shape whose proximal end is closed by a proximal wall,
    The liquid administration set according to any one of claims 3 to 6, wherein the third engagement portion is formed on the proximal end wall.
  8. 　前記第１の係合部は、前記外筒の基端側に設けられている請求項１ないし７のいずれか１項に記載の液体投与セット。 The liquid administration set according to any one of claims 1 to 7, wherein the first engagement portion is provided on a proximal end side of the outer cylinder.
  9. 　前記ケーシングには、軸方向に延びる長手形状の複数の腕部が設けられており、
    　前記第２の係合部は、前記各腕部にそれぞれ設けられている請求項１ないし８のいずれか１項に記載の液体投与セット。     The casing is provided with a plurality of longitudinal arm portions extending in the axial direction,
    The liquid administration set according to any one of claims 1 to 8, wherein the second engagement portion is provided in each of the arm portions.
  10. 　前記未使用状態では、前記内筒の基端部は、前記外筒の基端部から基端方向に突出しており、
    　前記内筒押圧部は、前記内筒の基端部を押圧するものである請求項１ないし９のいずれか１項に記載の液体投与セット。     In the unused state, the proximal end portion of the inner cylinder protrudes from the proximal end portion of the outer cylinder in the proximal direction,
    The liquid administration set according to any one of claims 1 to 9, wherein the inner cylinder pressing portion presses a proximal end portion of the inner cylinder.
  11. 　前記内筒押圧部は、前記プランジャの外周に配置されている請求項１ないし１０のいずれか１項に記載の液体投与セット。 The liquid administration set according to any one of claims 1 to 10, wherein the inner cylinder pressing portion is disposed on an outer periphery of the plunger.
  12. 　前記液体が薬液である請求項１ないし１１のいずれか１項に記載の液体投与セット。 The liquid administration set according to any one of claims 1 to 11, wherein the liquid is a chemical solution.
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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH02502971A (en) * 1987-05-08 1990-09-20 ヴィルヘルム　ハゼルマイヤー　ゲー・エム・ベー・ハー＋ツェー・オー Injection device with cocking element and second setting element
JP2011509783A (en) * 2008-01-23 2011-03-31 ノボ・ノルデイスク・エー／エス Device for injecting a liquid dose of an allotted dose

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