JP6074051B2 - 血管内神経変調システム及び医療用デバイス - Google Patents
血管内神経変調システム及び医療用デバイス Download PDFInfo
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- A61B2018/00571—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for achieving a particular surgical effect
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- A61B2018/00642—Sensing and controlling the application of energy with feedback, i.e. closed loop control
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- A61B2018/00696—Controlled or regulated parameters
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- A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
- A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
- A61B18/14—Probes or electrodes therefor
- A61B2018/1467—Probes or electrodes therefor using more than two electrodes on a single probe
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
- A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
- A61B18/14—Probes or electrodes therefor
- A61B18/16—Indifferent or passive electrodes for grounding
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Description
ある種の治療は、選択した神経機能の一時的又は恒久的な中断又は改変を必要とする。一例の治療は腎神経のアブレーションであり、これは時にうっ血性心不全又は高血圧に関係する状態を治療するために使用される。腎臓は、うっ血性心不全に対して交感神経性の応答を生じ、これは数ある効果の中でも特に、水及びナトリウムのうち少なくともいずれかの望ましからぬ貯留を増大させる。腎臓へと走行する神経のうちの一部をアブレーションすることにより、この交感神経性の機能を低減又は排除することが可能であり、このことは付随する望ましからぬ症状の相応の低減をもたらす可能性がある。
本開示は、医療用デバイスの構造体及び組立体のための、いくつかの代替の設計物、材料及び使用法選択肢に関する。一例の使用法には、血管内での腎神経変調を実施する方法が含まれる。該方法は、基端領域及び先端領域を有する長尺状シャフトと、該長尺状シャフトの先端領域に隣接して位置付けされた1以上のアブレーション電極と、を備えた神経変調システムを提供することを含む。該システムは、2以上の接地パッド、1以上のアブレーション電極に電気的に結合された制御ユニット、及び2以上の接地パッドに電気的に結合されたプロセッサをさらに備える。該変調システムは、管腔を通して前進せしめられて、先端領域が標的領域に隣接するようになされる。その後、1以上のアブレーション電極に電圧が印加されるが、エネルギーは1以上のアブレーション電極と2以上の接地パッドとの間を流れて個別の回路を形成する。接地パッドとアブレーション電極との間で形成される回路のうち少なくとも1つの抵抗を調整する。
以降の定義された用語については、異なる定義が特許請求の範囲又は本明細書中の他所に示されないかぎり、これらの定義が適用されるものとする。
様々な構成要素、特徴及び仕様のうち少なくともいずれかに関するいくつかの適切な寸法、範囲及び値のうち少なくともいずれかが開示されるが、本開示により触発された当業者は、所望の寸法、範囲及び値のうち少なくともいずれかが明示的に開示されたものから逸脱する場合があることを理解するであろう。
以降の詳細な説明は図面を参照して読まれるべきであり、該図面において、異なる図面中の類似の要素には同じ番号が付されている。詳細な説明及び図面(必ずしも一定の縮尺ではない)は例証となる実施形態を示しており、本発明の範囲を限定するようには意図されていない。図示された例証の実施形態は、単なる実例として意図される。任意の例証の実施形態の選択された特徴は、そうでないことが明白に述べられないかぎり、追加の実施形態に組み込まれることができる。
Claims (8)
- 血管内神経変調システムであって、
基端領域及び先端領域を有する長尺状シャフトと、
長尺状シャフトの先端領域に隣接して位置付けられた複数のアブレーション電極と、
少なくとも2個の接地パッドと、
複数のアブレーション電極に電気的に結合され、かつ、複数のアブレーション電極に電圧を供給するように構成されている制御ユニットと、
少なくとも2個の接地パッドに電気的に結合されたプロセッサと、
を含んでなり、
複数のアブレーション電極の各々と少なくとも2個の接地パッドの各々との間に個別の回路が形成され、
プロセッサは、個別の回路のインピーダンスをモニタリングするように構成されており、
プロセッサは、個別の回路が略同じインピーダンスを有するように、個別の回路の抵抗を変調するように構成されている、
血管内神経変調システム。 - 少なくとも2個の接地パッドは第1の接地パッド及び第2の接地パッドを含み、第1の接地パッドは所望の治療場所の第1の側に隣接して位置付けられ、第2の接地パッドは所望の治療場所の第2の側に隣接して位置付けられる、請求項1に記載の血管内神経変調システム。
- 所望の治療場所の第3の側に隣接して位置付けられる第3の接地パッドをさらに含んでなる、請求項2に記載の血管内神経変調システム。
- 医療用デバイスであって、
先端領域を有するカテーテルシャフトと、
カテーテルシャフトの先端領域に隣接して位置付けられた複数のアブレーション電極と、
患者の外側表面に沿って配置されるように設計された少なくとも2個の接地パッドと、
複数のアブレーション電極に電気的に結合された制御ユニットと、
少なくとも2個の接地パッドに電気的に結合されたプロセッサと、
を備え、
複数のアブレーション電極の各々と少なくとも2個の接地パッドの各々との間に個別の回路が形成されており、
プロセッサは個別の回路のインピーダンスをモニタリングするように構成されており、
少なくとも2個の接地パッドのうち少なくともいくつかは、個別の回路がプロセッサによってモニタリングされたときに異なるインピーダンスを有しており、
プロセッサは、個別の回路が略同じインピーダンスを有するように、個別の回路の抵抗を変調する、
医療用デバイス。 - 制御ユニットは複数のアブレーション電極に電圧を印加する、請求項4に記載の医療用デバイス。
- 少なくとも2個の接地パッドは第1の接地パッド及び第2の接地パッドを含み、第1の接地パッドは所望の治療場所の第1の側に隣接して位置付けられ、第2の接地パッドは所望の治療場所の第2の側に隣接して位置付けられる、請求項4又は5に記載の医療用デバイス。
- 所望の治療場所の第3の側に隣接して位置付けられる第3の接地パッドをさらに含んでなる、請求項6に記載の医療用デバイス。
- 医療用デバイスは腎動脈の周囲に位置する腎神経を変調するように構成されている、請求項4〜7のいずれか1項に記載の医療用デバイス。
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US201261712138P | 2012-10-10 | 2012-10-10 | |
US61/712,138 | 2012-10-10 | ||
PCT/US2013/064370 WO2014059165A2 (en) | 2012-10-10 | 2013-10-10 | Renal nerve modulation devices and methods |
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JP2015531304A JP2015531304A (ja) | 2015-11-02 |
JP6074051B2 true JP6074051B2 (ja) | 2017-02-01 |
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US (1) | US10835305B2 (ja) |
EP (1) | EP2906135A2 (ja) |
JP (1) | JP6074051B2 (ja) |
CN (1) | CN104869930B (ja) |
WO (1) | WO2014059165A2 (ja) |
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2013
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