JP4141097B2 - Medicine bag printing device - Google Patents

Description

[0001]
BACKGROUND OF THE INVENTION
  The present invention relates to a medicine bag printing apparatus used in a hospital pharmacy or the like, and more particularly, to a technique for performing related notation related to formulation when printing prescription information about a medicine to be stored in a medicine bag on a medicine bag.
[0002]
[Prior art]
  In addition to the printer that prints on the medicine bag, the medicine bag printing device is provided with an information processing device that creates the printing information from the prescription information. In addition to input means such as a keyboard, a reading device or a communication device for inputting information, storage means such as a hard disk is also provided. In the storage means, known information relating to various drugs is stored in advance. For example, a drug code, a drug name, and the like are held in a drug master file or a derivative file thereof.
[0003]
  When prescription information is input, a series of information such as a patient name, a drug name, and a dose included in the prescription information is converted into print information in a format suitable for printing and printed on a medicine bag. At that time, by referring to the drug master file etc., if the prescription instruction is in the drug code, it is converted to the drug name, and if the prescription instruction is in the titer, it is converted to the dose. Processing is also performed. Furthermore, when the medicine master file or the like includes an explanation of each medicine, the explanation is also added and printed on the medicine bag.
[0004]
  In addition, in automatic dispensing equipment, in order to more reliably prevent prescriptions of inappropriate drugs, known information on incompatibility is retained, and drugs specified in prescriptions and dispensing data prior to dispensing operations Some of them determine or display whether or not they may be blended.
[0005]
[Problems to be solved by the invention]
  Therefore, in order to reliably prevent the use of inappropriate drugs not only at the time of dispensing but also at the application stage, when prescription information etc. is printed on the medicine bag with the medicine bag printing device, it is also possible to add the possibility of blending. Conceivable.
  However, while general contraindications are confirmed and confirmed for each pair of drugs, for some drugs, the propriety of blending varies depending on the dose, etc. Some of them have limitations. For example, when an injection effective in an acidic state and an injection effective in an alkaline state are blended, the pH value (pH value, index value) indicating the degree of acid-alkali after mixing is within any effective range. It would be good, but otherwise the medicinal effect would be impaired. Since such drugs have various types and blending conditions, it is difficult to determine the blending results for every pair.
[0006]
  In addition, such injections are often diluted with an infusion solution such as physiological saline, and in that case, each injection may be mixed into the infusion solution according to the basic work procedure at the time of formulation. In cases where it is necessary, the user may be distracted by the promotion of the blending work, and may inadvertently confirm and mix injections before thinning.
  For this reason, it is desired not only to indicate whether or not the composition can be added when printing on the medicine bag, but also to describe useful information even in the above case.
  Therefore, it is a technical problem to further devise the printing of the medicine bag in order to reduce the burden on the user and the like necessary for confirming the change in the composition of the medicine due to the variation of the acid alkali at the time of the composition.
[0007]
  This inventionAn object of the present invention is to provide a medicine bag printing apparatus that prints information on a medicine bag that can easily confirm a change in composition.
[0008]
[Means for Solving the Problems]
[0009]
  The medicine bag printing apparatus according to claim 1 inputs a prescription information and a printer for printing on the medicine bag.Do An input means and a storage means for holding known information about the medicine, and the prescription information input by the input means is based on the known informationIn the medicine bag printing apparatus provided with an information processing apparatus that converts the print information into the printer and sends it to the printer, the known information includes:MultipleAbout the drugsIn addition to information indicating whether or not it is possible to blend, a self-pH value indicating the acid alkalinity of the drug itself andAn index value indicating the effective range of acid-alkali is included, andIs,Of the plurality of medicines determined to be blendable by the blending impossibility confirmation means for determining whether blending is possible or impossible for each of the plurality of medicines indicated in the prescription information For all combinations of two types of drugs, the pH value at the time of formulation is calculated based on the dose indicated by the prescription information and the self-pH value, and the effective range of the acid-alkali of the corresponding drug is calculated. To determine the appropriateness of fluctuations in pH valueAcid-alkaline fluctuation confirmation meansIt is characterized by having.
[0010]
  ThisMedicineIn bag printing equipmentInThe printing information is created by the information processing device and printed on the medicine bag by the printer. When the information processing device converts the prescription information from the prescription information based on the known information of the medicine, For each drug included in the known information in advance by the confirmation meansThe acid alkalinity of the drug itselfThe effective range of acid-alkali is referred to, and based on that, it is indicated in the prescription information.For a combination of two types of drugs determined to be blendable, the pH value at the time of blending of the drugs to be used for this blendingA determination is made whether there is a possibility of deviating from the effective range of the acid alkali.
[0011]
  As a result, the determination result can be reflected in the print information, and by doing so, information contributing to confirmation of a blending change different from the blending possibility is printed on the medicine bag. Specifically, if the user, etc., removes the injection from the medicine bag, he / she should be careful to confirm the change in the composition of the drug due to the change in acid / alkaline at the time of formulation. Aroused. In addition, since the determination of the composition change is performed dynamically each time the printing corresponding to the prescription is performed, the information to be provided as known information for confirming the composition change is sufficient for the index value for each individual medicine. As a result, it is not necessary to prepare a large amount of information by predetermining relationships with many other drugs, and it is easy to update data when adding a new drug.
  Therefore, according to the present invention, it is possible to realize a medicine bag printing apparatus that can print information on a medicine bag that can easily confirm a change in composition.
  The medicine bag printing apparatus according to claim 2 has a printer for printing on the medicine bag, an input means for inputting prescription information, and a storage means for holding known information about the medicine, and the prescription information input by the input means In the medicine bag printing apparatus comprising an information processing apparatus that converts the print information into print information based on the known information and sends the information to the printer, the known information includes a medicine itself in addition to information indicating whether or not a plurality of medicines are blended. A self-pH value indicating the acid alkalinity of the acid, an index value indicating the effective range of the acid alkali, and buffer capacity information indicating the susceptibility to the influence of the acid alkali by other chemicals at the time of blending. Is a blending impossibility confirmation unit for determining whether blending is possible or not for each of the plurality of drugs instructed by the prescription information, and a plurality of blending determined by the blending impossibility confirmation unit For all combinations of two types of drugs, it is determined whether the self-pH value of one drug is within the effective range of the acid-alkali of the other drug. Further, the present invention is characterized by comprising acid-alkali fluctuation confirmation means for judging the suitability of the pH value fluctuation by judging the acid-alkali fluctuation based on the buffer capacity information.
  In this medicine bag printing apparatus, two kinds of medicines out of a plurality of medicines determined to be blendable by the blending impossibility confirming means without using the dose as in claim 1 by the acid-alkali fluctuation confirming means of the information processing apparatus For each of the combinations, it is determined whether the self-pH value of one drug is within the effective range of the acid-alkali of the other drug, and if a negative determination is made, the acid value is determined based on the buffer capacity information. It can be judged about the variation of alkali.
[0012]
  Of claim 3Medicine bag printing deviceThe invention according to claim 1 or 2, wherein the acid-alkali modification. Depending on the judgment result of the motion confirmation means,Information to call attention to acid-alkali fluctuationsSelectOptionally included in the print informationIt is characterized by that.
  ThisMedicineIn bag printing equipmentInIn the medicine bag containing the medicine that needs to confirm the change in the composition of the medicine due to the variation of the acid-alkaline at the time of blending, a precautionary note for caution is clearly stated. Thereby, when taking out an injection etc. from a medicine bag, an applicator etc. comes to confirm the mixing | blending change of the chemical | drug | medicine resulting from the fluctuation | variation of an acid alkali naturally naturally even in an emergency. Therefore, according to the present invention, it is possible to easily confirm a change in the composition of the drug.
[0013]
  Claim 4Medicine bag printing deviceIn any one of Claims 1-3,According to the determination result of the acid-alkali fluctuation confirmation means, the classification information of the medicine is selectively included in the print information.It is characterized by that.
  ThisMedicineIn bag printing equipmentInIn the medicine bag containing the medicine that needs to confirm the change in the composition of the medicine due to the variation of the acid-alkali at the time of blending, the medicine to be noted at the time of blending is indicated separately. As a result, when taking out an injection medicine from a medicine bag, the user etc. naturally separates medicines that should be checked for changes in the composition of the medicine due to acid-alkali fluctuations, even in an emergency. It will be handled. Therefore, according to the present invention, it is possible to easily confirm a change in the composition of the drug.
[0014]
  Of claim 5Medicine bag printing deviceIn the invention according to any one of claims 1 to 4When the prescription information is converted into the print information, the order of the medicine notation is adjusted according to the determination result of the acid-alkali fluctuation confirmation means (that is, the order of notation regarding each medicine in the order of medicine).It is characterized by that.
[0015]
  ThisMedicineIn bag printing equipmentInIf necessary, the arrangement of the print information for each medicine is adjusted based on the determination result, and the information about the medicines to be careful of the combination is printed at a distance. As a result, when an agent or the like takes out an injection medicine from a medicine bag and mixes the medicines in the order of printing on the medicine bag, naturally, even in an emergency, naturally, an undesired combination of medicines to be noted However, for example, a situation in which only such a drug is directly mixed is avoided or hardly occurs. Therefore, according to the present invention, it is possible to realize a medicine bag printing apparatus that prints information on a medicine bag that can easily avoid change in composition.
[0016]
[0017]
[0018]
DETAILED DESCRIPTION OF THE INVENTION
  About the medicine bag printing device and medicine bag of the present invention achieved by such a solution, specific modes for carrying out this will be described with reference to the following first to fourth embodiments.
  The first embodiment shown in FIGS. 1 to 4 embodies all of the first to fourth solving means described above. The second embodiment shown in FIG. 5 and the first embodiment shown in FIG. The third embodiment and the fourth embodiment shown in FIG. 7 are modifications thereof.
  In the illustration, for the sake of simplification, the casing panel, the fasteners such as the base, the frame, and the bolts, and the couplings such as the hinges are omitted from the illustration, and those necessary for explaining the invention and related items are omitted. It is illustrated centering on what to do.
[0019]
[First embodiment]
  The specific configuration of the first embodiment of the medicine bag printing apparatus of the present invention will be described with reference to the drawings. FIG. 1A is a block diagram showing the overall structure, and FIGS. 1B to 1D show the data structures of a blending impossible file, a pH fluctuation file, and a blending attention file, respectively.
[0020]
  This medicine bag printing apparatus is provided with a printer 50 (printing apparatus) and a microprocessor 30 (main body of the information processing apparatus) for preparing the printing information.
  As long as the printer 50 can print on the medicine bag 20, it may be a transfer method, an ink jet method, or any other printing method, or may be a single unit (see Japanese Patent Application Laid-Open No. 2000-116753, etc.). A plurality of units may be arranged in parallel (see Japanese Patent No. 2905460). The medicine bag 20 may be transparent or opaque as long as it can contain medicine and can be printed, and may or may not have a gusset (see JP 2000-116753 A).
[0021]
  The microprocessor 30 may also serve as a controller for the printer 50. However, the microprocessor 30 is provided independently here and is connected to the printer 50 by a parallel printer cable, USB cable, or the like, and print information is sent to the printer 50. It can be transmitted and printed on the medicine bag 20.
  The microprocessor 30 includes a program holding memory and a built-in or external hard disk 40 (storage means) that holds known information about various drugs divided into several files 41 to 44. As an input means for inputting prescription information described in the prescription 10 or its equivalent, although not shown in the figure, a keyboard for manual input, an OCR for machine reading, a floppy (registered trademark) disk for batch processing, Either a communication unit for online processing or other input device is attached.
[0022]
  The medicine master file 41 of the hard disk 40 holds general information among known information. For example, a record is assigned to each medicine, and data such as a medicine code, a medicine name, and general explanation items of the medicine is recorded in each record.
[0023]
  In the unmixable file 42, information on drugs that are prohibited from being mixed among the known information is stored in order to indicate whether or not various drugs can be combined. For example, a record is assigned to each pair of medicines that cannot be combined, and each record contains one medicine code and the other medicine code of the pair, and the combination that cannot be combined is clearly indicated. . Although a file related to medicines that can be blended may be created actively, here, combinations that are not in the blending impossible file 42 can be blended.
[0024]
  The pH fluctuation file 43 holds known information necessary for the confirmation of a drug that is not prohibited to be blended but has a possibility of blending variation due to variation in acid and alkali. Specifically, a record is assigned to each such medicine, and in addition to the corresponding medicine code, for example, an infusion flag indicating whether or not the infusion is suitable for thinning, and the medicine itself The self-pH value (sample pH) that indicates the acid alkalinity of the product as a pH value, the buffering capacity that indicates the susceptibility to the effects of acid-alkali fluctuations caused by other drugs at the time of formulation, and the effective range of acid-alkali that maintains the drug efficacy The lower limit pH (acid pH, acid side change point pH, acid side final pH) which is one of the index values indicated by a pair of pH values, and the upper limit pH (alkaline pH, alkali side change point pH, which is the other of the pair) Data such as alkali side final pH and base side final pH) are recorded.
[0025]
  The compounding caution file 44 holds known information necessary for calling attention to a drug that has a possibility of not only acid-alkali variation but also other compounding variation. For example, a record is assigned to each pair of drugs requiring attention at the time of formulation, and each record is recorded with one drug code of the pair, the other drug code, and character string data of a caution sentence for the combination. It has become.
[0026]
  Further, the microprocessor 30 has known information about the medicine in order to perform a series of information processing such as converting prescription information input by the input means into print information based on the known information and sending it to the printer by program processing. A general information processing routine 31 for processing general information, a blending impossibility confirmation routine 32 (a blending impossibility confirming means) for determining whether blending is possible or impossible for the medicine indicated by the prescription information, PH variation confirmation routine 33 (acid / alkaline variation confirmation means) for determining whether or not there is a possibility that the medicine instructed in the prescription information is out of the effective range of each acid / alkali at the time of compounding, A combination caution confirmation routine 34 for selectively including information for calling attention in the print information according to the determination result of the pH fluctuation confirmation routine 33; And printing routine 35 to print the print information prepared at their routine bag and sent to the printer 50 20 is installed.
[0027]
  Further, the microprocessor 30 performs processing for selectively including the medicine classification information in the print information according to the determination result, for example, by processing such as the pH fluctuation confirmation routine 33, or when converting the prescription information to the print information. The process of adjusting the arrangement of the print information for each medicine is also performed according to the determination result. A series of processes by these routines 31 to 35 are executed every time prescription information of one prescription 10 is input. Details of the processes are exemplified in the following operation description. To do. In this example, for the sake of simplicity, it is assumed that all drugs have the same buffer capacity.
[0028]
  About the medicine bag printing apparatus of this 1st Example, the use aspect and operation | movement are demonstrated referring drawings. FIGS. 2A and 2B are specific examples of known drug information, in which FIG. 2A is a data example of a non-combination file, FIG. 2B is a data example of a pH fluctuation file, and FIG. FIG. 3A is an example of prescription information, and FIG. 3B is a printing example corresponding to the prescription information. Furthermore, FIG. 4A is another example of prescription information, and FIG. 4B is a printing example corresponding to it. In these drawings, the drug name such as the drug A and the drug code are indicated by the same letter “A” or the like without being distinguished from each other.
[0029]
  Here (see FIG. 2), the case of prescribing five types of drugs A to E will be described in detail. As known information about them, for example, it is assumed that mixing of drugs B and C is impossible, correspondingly The combination impossible file 42 includes a record in which drug codes B and C are grouped. Further, in the pH fluctuation file 43, in the record of the drug A, based on the characteristics of the drug A, for example, the infusion flag is a false value “−”, the self pH value is “6”, the buffer capacity is “·”, and the lower limit pH value is “3” and the upper limit pH value is set to “7.3”. Each item of other records, that is, the infusion flag, the self pH, the buffer capacity, the lower limit pH, and the upper limit pH are set in the same manner.
[0030]
  For example, when listing in the order of items, “−”, “9”, “•”, “6”, “10” are set in the record of medicine B, and “−”, “7. 1 ”,“ • ”,“ 5.2 ”,“ 9.3 ”are set, and“ ○ ”(value),“ 7 ”,“ • ”,“ 2 ”,“ 12 ”are set in the record of medicine D. ”Is set, and“ − ”,“ 7 ”,“ • ”,“ 5 ”,“ 10 ”are set in the record of the medicine E. Furthermore, for example, if the characteristic that a change in composition is likely to occur after about 1 hour when the drug A and the drug E are blended is known, the blending caution file 44 contains the drug codes of both drugs A and E. A record with a pair of cautionary statements “extremely yellowing after 1 hour” is included. These pieces of known information are recorded in the hard disk 40 prior to printing the medicine bag 20 by using an initial setting function of the medicine bag printing device, for example, when a new device is introduced or when a drug to be handled is subsequently added. ing.
[0031]
  A prescription 10 (see FIG. 3A) includes 250 mg of the first drug A, 250 mg of the second drug B, 250 mg of the third drug C, 500 ml of the fourth drug D, 5 It is assumed that a prescription instruction for injecting 250 mg of the second drug E at the same time is described. When the prescription information is input to the medicine bag printing device, the microprocessor 30 performs a general information processing routine 31, a blending inability confirmation routine 32, a pH fluctuation confirmation routine 33, a blending caution confirmation routine 34, and a printing routine 35 in that order. As a result, print information is created in the print information storage area allocated to the work RAM and the like, and is sent to the printer 50 to be printed on the medicine bag 20 (see FIG. 3B).
[0032]
  The processing will be described in detail step by step. First, the general information processing routine 31 executes the patient name and medicine bag number. In addition to general information such as, a fixed sentence such as a title of the medicine list 21 is included in the print information. In addition, the combination failure confirmation routine 32 searches whether or not the combination is included in the combination failure file 42 for all of the two combinations among the drugs instructed by the prescription information. If it is not included, it is determined that blending is possible. If it is included, it is determined that blending is impossible. If not, any one medicine is arranged in the print information for each medicine. Moved to the end. That is, it is printed at the bottom line in the medicine list 21 arranged from top to bottom. In this case, drug C comes to the bottom line. In addition, a partition line 23 composed of a double line or the like is printed between the line and the line immediately above, and a compound “impossible combination mark” is displayed at a corresponding portion of the propriety mark 25 displayed for each medicine in the medicine list 21. “×” is printed. Further, a note specifying the medicines B and C, for example, “BC × combination impossible” is also printed in the column of the note sentence 24 below the medicine list 21. Such data is included in the print information by the blending impossible confirmation routine 32.
[0033]
  Then, the pH fluctuation checking routine 33 searches the pH fluctuation file 43 for all the medicines instructed by the prescription information, and if there is a medicine whose infusion flag is “」 ”, the top line of the medicine list 21. Moved to. In this case, the drug D comes to the top row. Then, a mark “transfer” indicating that it is an infusion is added to the availability mark 25 in the row.
  In addition, the pH value of the acid-alkali when the stock solutions are directly mixed with each other for all of the two types of combinations determined to be compoundable among the medicines indicated in the prescription information by the pH fluctuation confirmation routine 33 is the pH fluctuation. It is calculated based on the self pH value and dose value of the file 43, and it is determined whether or not the pH value is within an effective range based on the lower limit pH value and the upper limit pH value of the pH fluctuation file 43.
[0034]
  If it is determined that the medicine is out of the effective range, any one of the medicines is moved to a row located immediately above the partition line 23 in the medicine list 21. In this case, when 250 mg each of Drug A and Drug B are mixed in the stock solution, the pH value becomes “7.5” and exceeds the upper limit pH value “7.3” of Drug A. It is determined that it is a combination that requires attention regarding alkali fluctuations, and the medicine B comes immediately above the partition line 23 based on the determination result. In addition, a partition line 22 (segment information, segment notation) composed of a single line or the like is printed between the row and the row immediately above, and a note that specifies the drugs A and B is also displayed in the note 24 column. For example, “● Same syringe pH caution 1 (A) 2 (B)” is printed. In addition, like the medicine E, the medicine “A” and “B” are also printed with a compoundable mark “◯” at the corresponding portion of the availability mark 25. Such data is included in the print information.
[0035]
  Further, the combination caution confirmation routine 34 performs a search to determine whether or not the combination is included in the combination caution file 44 for all of the two combinations among the drugs instructed by the prescription information. If there is, a caution sentence is read from the corresponding record and is also included in the print information. In this case, since the pair of medicines A and E is applicable, the note 24 includes a note that specifies the medicines A and E, for example, data such as “extremely yellowing after AE 1 hour” is printed. It is done.
[0036]
  The print information thus prepared is sent to the printer 50 by the printing routine 35 and printed on the medicine bag 20 by the printer 50. On the printed surface of the completed medicine bag 20, in addition to prescription information (medicine list 21) in which the order of the medicines is prepared, a cautionary note (note 24) regarding acid-alkaline variation due to the blending, and the medicines that can be blended A section notation (partition line 22) that separates them from each other based on the variation of acid-alkali at the time of blending is also printed.
[0037]
  Then, each medicine A to E is accommodated in the medicine bag 20, which is used for the treatment of the patient through a final audit and the like, and the medicines A to E are taken out from the medicine bag 20 at the time of application. And in order to speed up application by performing injection and infusion as much as possible, possible drugs are blended. At that time, in order to confirm the drug to be blended, the applicator etc. The medicine list 21 of the medicine bag 20 is read together with the label. Then, naturally, the user or the like proceeds with the blending work in the order of the medicines in the medicine list 21, and in this case, the medicine D to be a thinning liquid is picked up first, and then the medicine A is picked up and mixed with the medicine D. Then take up drug E and mix it. Furthermore, the medicine B is also picked up and mixed, but at that time, attention is urged by the partition line 22 that naturally enters the eye, and further attention is given by the notice of the note 24 that stands out in red or the like. Therefore, an undesired situation in which at least the medicine B is mixed with the stock solution of the medicine A as a stock solution is surely avoided even in an emergency. Similarly, since the medicine C is alerted by the partition line 23 and the note 24, an inconvenient situation of mixing with another medicine is avoided.
[0038]
  The other prescription 10 (see FIG. 4A) includes 500 mg of the first drug A, 250 mg of the second drug B, 250 mg of the third drug C, 500 ml of the fourth drug D, 5 It is assumed that a prescription instruction for injecting 250 mg of the second drug E at the same time is described. In this case, the first drug A is doubled to 500 mg, but the doses of the other drugs B to E are the same as described above. When the prescription information is input to the medicine bag printing apparatus, the print information is created from the prescription information based on the files 41 to 44 by the routines 31 to 35 as in the case described above.
[0039]
  In this case, the processing of the general information processing routine 31 that does not refer to the dose of the medicine, the blending impossible confirmation routine 32, the blending caution confirmation routine 34, and the printing routine 35, and the printing items thereby are the same as in the above case, but depending on the blending The determination of the combination failure confirmation routine 32 regarding the acid-alkali variation is influenced by the dose of the drug. That is, in this case, mixing of the stock solution of 500 mg of drug A and 250 mg of drug B is considered, and the pH value at that time is “7”, which falls within the effective range of both drugs A and B. And the drug B are also determined to be combinations that do not require attention regarding acid-alkali fluctuations. And based on this determination result, the order adjustment of the medicines A and B in the medicine list 21, the printing of the partition line 22, and “● same syringe pH caution 1 (A) 2 (B)” And the like are not printed (see FIG. 4B).
[0040]
  Thus, it is necessary to call attention based on the determination result by the pH variation confirmation routine 33, that is, the determination result of whether or not there is a possibility that the medicine instructed by the prescription information is out of the effective range of each acid-alkali at the time of combination. If there is, the corresponding notice and classification notation are printed and the order of the drugs is adjusted. For this reason, if the user or the like naturally performs the work while looking at the medicine bag 20, even if the user does not inadvertently confirm the action, the probability of an unfavorable change in composition is small. Loss can be reduced.
[0041]
[Second embodiment]
  By the way, the precautions etc. on the medicine bag according to the present invention are for prompting the user / combination worker to check carefully so as not to neglect the confirmation of the change of the composition, regardless of the presence or absence of the precautionary notice. Basically, each drug is diluted individually when blended. In other words, even drugs that are outside the scope of the precautionary statement must be blended while being diluted with an infusion solution, etc., and there is no precautionary note in the medicine bag or the same classification allows direct mixing of the drugs. Not. The present invention is intended only to alert the user and the like.
[0042]
  However, when there are many caution notes, the attention is often distracted by the adverse effect. Therefore, as described above, the precautions on the medicine bag do not allow direct mixing of the medicines, and the processing load of the information processing apparatus is heavy because the judgment processing is performed dynamically, so the amount of computation is reduced. In consideration of the point of speeding up, it may be better to narrow down the target drug for which attention is paid to the variation in the composition by another method. FIG. 5 shows an example of a medicine bag printing apparatus whose pH fluctuation file data is shown in FIG. 5. In this medicine bag printing apparatus, the pH fluctuation confirmation routine 33 makes a simple determination based on buffer capacity rather than dose. This is different from the first embodiment described above.
[0043]
  When the difference is described in detail (refer to FIG. 5A), the buffer capacity data in the pH fluctuation file 43 includes the items of the acid buffer capacity (acid side buffer capacity) assigned to each drug and the alkali buffer capacity (base). It is to be held in the item of the side buffer capacity. Each item takes the value of “strong” or “weak”, and the acidic buffer capacity is considered to be “strong” when it is difficult to lower the pH when acidic substances with small pH values are mixed. Those that tend to lower the pH are considered “weak”. As for the alkaline buffering ability, when an alkaline substance having a large pH value is mixed, the one that hardly raises the pH is “strong”, and the one that easily raises the pH is “weak”. Specifically, for each of the records of drugs A to E, the acidic buffer capacity is “strong”, “strong”, “weak”, “strong”, “weak”, and the alkaline buffer capacity is “weak”, “strong”. ”,“ Strong ”,“ weak ”,“ strong ”. For the purpose of comparison, the self pH of the medicine E is changed to “8”.
[0044]
  Further, the pH fluctuation confirmation routine 33 is configured such that the self-pH value of one drug is the lower limit pH value and the upper limit of the other drug for all of the two types of combinations determined to be mixable among the drugs indicated in the prescription information. It is determined whether or not it is within the effective range based on the pH value, and if it is determined that any of the drugs is out of the effective range, the acid buffer capacity of one drug and the alkali buffer capacity of the other drug do not coincide. If the mismatch between the alkali buffering capacity of one drug and the acidic buffering capacity of the other drug is examined and the mismatch is found, the set / pair of drugs is the subject of the cautionary note or the like. Otherwise, even if any of them is out of the effective range, it is removed from the target to call attention. The processing of the pH fluctuation confirmation routine 33 is changed as such.
[0045]
  In this case, if the same prescription 10 (see FIG. 3A) as in the above example is given, the self-pH value of the drug B and the self-pH value of the drug E from the pH fluctuation file 43 (see FIG. 5A). Is exceeding the upper limit pH value of the drug A, and in addition to the pair of the drug A and the drug B, the pair of the drug A and the drug E is also determined to be out of the effective range by the pH variation confirmation routine 33. . Further, for these pairs, a further determination process based on the buffer capacity is also performed by the pH fluctuation confirmation routine 33. That is, in this example, since the self pH of the drug A is smaller than the self pH of the drug B, the alkaline buffering capacity of the drug A and the acidic buffering capacity of the drug B are compared, and there is a mismatch between “weak” and “strong”. The pair of A and B is a target of a note or the like. Further, since the self pH of the drug A is smaller than the self pH of the drug E, the alkali buffer capacity of the drug A and the acid buffer capacity of the drug B are also compared. , E are excluded from the notes.
[0046]
  Thus, it is determined that drug A and drug B are combinations that require attention regarding acid-alkaline fluctuations, but drug A and drug E are determined not to call attention and attention should be paid. Encouragement targets are narrowed down. As a result, information similar to the above example is printed on the medicine bag 20 (see FIG. 3B). In addition, although repeated detailed description is omitted, in this case, even if the dose of any drug, for example, drug A is different (see FIG. 4A), the same information is printed (FIG. 3B). )reference). Although not shown in this example, when the self pH of the drug A is higher than the self pH of the drug B, the acid buffer capacity of the drug A and the alkali buffer capacity of the drug B are compared.
[0047]
  In addition, when a new drug is newly handled due to the development of a new drug or the like, first, a pH fluctuation test is performed on the drug F alone, and specifically a standard reagent (for example, hydrochloric acid HCl or sodium hydroxide). A test such as examining the maintenance / loss of the efficacy of the medicine F while changing the acid alkalinity with NaOH) is performed to obtain known information necessary for confirming the blending variation caused by the variation of the acid alkali. For example, if data such as a self pH value of “7”, an acidic buffer capacity of “weak”, an alkaline buffer capacity of “weak”, a lower limit pH of “4”, and an upper limit pH of “11” are obtained, Additional setting is made in the fluctuation file 43 (see FIG. 5B).
[0048]
  In this case, the same applies to the first embodiment described above. However, as known information necessary for confirming the blending variation set in the pH variation file 43, the data set in the blending impossibility file 42 and the pH variation file 43 and In contrast, the value of the drug F alone is sufficient. After the information of the medicine F is set, the pH variation confirmation routine 33 dynamically performs determination processing for the combination of the medicine F and the other medicines A, B,.
  In this way, the data update accompanying the addition of a new drug can be easily done.
[0049]
[Third embodiment]
  The medicine bag printing apparatus whose file structure is shown in FIG. 6 is different from that in the first embodiment described above. The combination impossible file for storing known drug information and the combination precaution file are integrated into one file. Is a point.
[0050]
  This file employs a data structure in which each record is arranged in a matrix (two-dimensional array), so that the corresponding record can be read quickly by using one of the pair of medicine codes as a row address and the other as a column address. It has become. Each record holds a flag indicating whether or not blending is possible, a combination that cannot be blended, and a caution statement about combinations that require attention even if blending is possible. .
[0051]
[Fourth embodiment]
  The difference between the medicine bag printing apparatus whose file structure is shown in FIG. 7 and that of the first embodiment is that the files holding the known information of the medicine are integrated into one, including the pH fluctuation file. is there.
[0052]
  In this case, the medicine master file 41 and the pH fluctuation file 43 that can specify a record with one medicine code are integrated by merging items for each record, and the blending impossible file 42 and the blending caution file 44 are added with a list. Integrated. More specifically, a record is assigned to each medicine, and each record has an unacceptable list in addition to items such as a medicine code, a medicine name, an infusion flag, a self pH value, a buffer capacity, a lower limit pH, and an upper limit pH. And a pointer to the attention list are recorded. In these lists, the other drug code and the caution statement that are paired are connected.
[0053]
  NaIn each of the above embodiments, the known information of the medicine is placed on the hard disk, but the means for storing the known information is not limited to such secondary storage, and may be, for example, a ROM or a flash memory. good. Further, the data structure of the known information is not limited to the above-described file, and is arbitrary as long as a search or the like is possible. For example, a fixed length format or a variable length format may be used, and a direct access method or a sequential file with or without an index may be used. Instead of the file format, it may be a simple table format or a specialized part of a ready-made database.
[0054]
  Further, printing may be in black and white or in color, but it is desirable to express notices etc. prominently. The partition line may be either black and white or color, and is not limited to a broken line, but may be a solid line or another line. The division notation is not limited to the use of the partition line, may use a frame, may use a blank line, a paragraph, or the like, and may be anything that can be visually recognized as a break.
[0055]
  In addition, in the determination of pH fluctuation confirmation, the buffer capacity was not reflected by reflecting the dose in the first embodiment, and the buffer capacity was reflected without reflecting the dose in the second embodiment. The application is not limited to this, and both dose and buffer capacity may be reflected or not reflected. For example, a further condition based on the dose may be determined only when the buffering capacities of the two drugs match.
[0056]
【The invention's effect】
  As is clear from the above explanation,Claim 1For medicine bag printerAccording toWhen creating the printing information, it is determined whether or not there is a possibility that it is out of the effective range of acid-alkali at the time of blending the prescription target drug. There is an advantageous effect that a medicine bag printing apparatus for printing can be realized.
  According to the medicine bag printing device of claim 2, among the plurality of medicines that are determined to be compoundable by the compounding inability confirmation unit without using the dose as in claim 1 by the acid-alkali fluctuation confirmation unit of the information processing device. For all combinations of the two types of drugs, if the determination of whether the self-pH value of one drug is within the effective range of the acid-alkali of the other drug is negative, Based on the above, it is possible to determine the variation of the acid alkali.
[0057]
  Of claim 3For medicine bag printerAccording toIn addition, it is possible to easily confirm the change in the composition of the medicine by clearly indicating the precautionary note on the medicine bag and prompting the attention of the user and the like.
[0058]
  Claim 4For medicine bag printerAccording toSince the medicines to be noted at the time of blending are classified and displayed in the medicine bag, there is an advantageous effect that it is possible to easily check the blending change of the medicine.
[0059]
  Of claim 5For medicine bag printerAccording toBy arranging and printing in the order in which the blending change is unlikely to occur, there is an advantageous effect that a medicine bag printing apparatus for printing information that can easily avoid the blending change on the medicine bag can be realized.
[Brief description of the drawings]
FIG. 1 of the present inventionAccording to the first embodimentMedicine bag printing deviceConfiguration(A) is an overall block diagram, (b) is a data structure of a non-combinable fileIllustration of, (C) is the data structure of the pH fluctuation fileIllustration of, (D) is the data structure of the compounding notes fileIllustration ofIt is.
[Fig. 2] Specific examples of known drug informationIndicate, (A) is an example of data that cannot be formulatedIllustration of, (B) Data example of pH fluctuation fileIllustration of, (C) is a data example of a compounding attention fileIllustration ofIt is.
FIG. 3 shows an example of prescription information and corresponding print information.(A) is explanatory drawing of prescription information, (b) is explanatory drawing of a medicine bag and its printing information.
FIG. 4 shows another example of prescription information and corresponding print information.(A) is explanatory drawing of prescription information, (b) is explanatory drawing of a medicine bag and its printing information.
FIG. 5 shows a second embodiment of the medicine bag printing apparatus of the present invention.About(A), (b)IsData examples of files that cannot be blendedIllustration ofIt is.
FIG. 6 shows a third embodiment of the medicine bag printing apparatus of the present invention.Related, The data structure of the file that combines the compounding impossible file and the compounding attention fileIllustration ofIt is.
FIG. 7 shows a fourth embodiment of the medicine bag printing apparatus of the present invention.Related, The data structure of the file that integrates the medicine master file, pH fluctuation file, compounding impossible file and compounding caution fileIllustration ofIt is.
[Explanation of symbols]
10 Prescription (Carrier of input prescription information)
20 medicine bags
21 Medicine list (printed prescription information, print information)
22 Dividing lines (drug category information, category notation, print information)
23 Separation lines (medicine category information, category notation, print information)
24 Notes (Information to call attention, notes, print information)
25 Acceptability mark (printing information)
30 Microprocessor (MPU, CPU, computer, information processing equipment)
31 General information processing routine
32 Mixing Impossibility Confirmation Routine (Mixing Impossibility Confirming Method)
33 pH fluctuation confirmation routine (acid-alkali fluctuation confirmation means)
34 Compounding Caution Confirmation Routine
35 Print routine (print information sending means)
40 Hard disk (nonvolatile memory, storage means)
41 Drug Master File (General information and known information about various drugs)
42 Unable to blend file (information indicating blendability, known information)
43 pH fluctuation file (information indicating the effective range of acid-alkali, known information)
44 Compounding notes file (information to call attention, known information)
50 printers

Claims (5)

A printer that performs printing on a medicine bag, an input unit that inputs prescription information, and a storage unit that holds known information about the medicine, and converts prescription information input by the input unit into print information based on the known information In the medicine bag printing apparatus provided with an information processing device for sending to the printer,
The known information includes a self-pH value indicating the acid alkalinity of the drug itself and an index value indicating the effective range of the acid alkali, in addition to information indicating whether or not a plurality of drugs can be combined .
The information processing equipment is,
A blending impossibility confirmation means for determining whether blending is possible or not for each of the plurality of medicines indicated in the prescription information;
About all combinations of two kinds of medicines determined to be blendable by the blending impossibility confirmation means, the pH value at the time of blending based on the dose indicated by the prescription information and the self-pH value, respectively. Acid-alkaline fluctuation confirmation means for determining the suitability of the fluctuation of the pH value by calculating the pH value and comparing the effective range of the acid-alkali of the corresponding drug ,
Bag printing apparatus comprising the. A printer that performs printing on the medicine bag, an input unit that inputs prescription information, and a storage unit that holds known information about the medicine, and converts prescription information input by the input unit into print information based on the known information In the medicine bag printing apparatus provided with an information processing device for sending to the printer,
In the known information, for a plurality of drugs , in addition to information indicating whether or not the drug can be blended, a self-pH value indicating the acid alkalinity of the drug itself, an index value indicating the effective range of the acid alkali, and acids by other drugs at the time of blending includes the buffering capacity information indicating the susceptibility to the influence of alkali,
The information processing equipment is,
A blending impossibility confirmation means for determining whether blending is possible or not for each of the plurality of medicines indicated in the prescription information;
For all combinations of two types of drugs that are determined to be compoundable by this combination non-confirmation means, whether the self-pH value of one drug is within the acid-alkali effective range of the other drug If the determination is negative and if a negative determination is made, acid / alkaline fluctuation confirmation means for judging the suitability of the fluctuation of the pH value by judging the fluctuation of the acid / alkali based on the buffer capacity information ,
Bag printing apparatus comprising the. According to the determination result of the alkali varies confirmation means, medicine bag printing apparatus according to claim 1 or 2, characterized in that included in the printing information alerting information to the selected択的respect fluctuation of alkali. The medicine bag printing apparatus according to any one of claims 1 to 3 , wherein medicine information is selectively included in the print information according to a determination result of the acid-alkali fluctuation confirmation means. The medicine bag printing apparatus according to any one of claims 1 to 4 , wherein when the prescription information is converted into the printing information, the order of the medicine notation is adjusted in accordance with the determination result of the acid-alkali fluctuation confirmation means. .

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