JP3992705B2 - Display device of magnetic field measuring device - Google Patents

Description

The present invention relates to a display device for a magnetic field measurement apparatus that measures a magnetic field of a living body caused by a current in the living body such as a nerve activity of a brain in a living body or a myocardial activity of a heart.

  Using a superconducting quantum interference device (SQUID), which is a conventional magnetic sensor, measure the distribution of the weak magnetic field generated from the living body, and estimate the position of the active current inside the living body from the measurement result. A multi-channel biomagnetic imaging apparatus for imaging is known. Such a conventional example is disclosed in, for example, published publications such as Patent Document 1 or Patent Document 2.

JP-A-4-319334 JP-A-5-146416

The conventional example relates to an operating principle related to the biomagnetic imaging apparatus, and the disclosed contents do not disclose technical problems and solution means for implementation. Further, the conventional example relates to a bioactive current generated in the brain, and no specific disclosure about other parts is made.
The objective of this invention is providing the display apparatus of the magnetic field measuring device of the biological body with favorable operativity and visibility.

To achieve the above object, the present invention detects a magnetic field emitted from a living body of a subject by a plurality of magnetic sensors, and displays a measurement data based on the detection result in an arbitrary display form. A processing function display unit for selecting an operation menu including a subject list, data measurement or data analysis, a subject information display unit representing information on the selected subject, a data display region, The data display area can be switched to a magnetic field diagram display screen divided into left and right, and the magnetic field diagram display screen is arranged on the left side and the subject is displayed. and analyzing the data display unit for displaying a waveform diagram measured by said plurality of magnetic sensor of the subject selected in the list section, disposed on the right side for processing operations the waveform displayed on the analysis data display unit Operation procedure And a display unit, the manipulation area display unit is provided with a heat flash as an operation menu for processing the waveform displayed in the analysis data display section, when the heat flash is selected, said corrugated diagram measured is the A heat flash operation screen for accepting selection of a magnetic sensor to be heat-flashed among the plurality of magnetic sensors displayed on the analysis data display unit is newly displayed on the operation information display screen.

According to the present invention, the heat flash operation screen has a list of channels of the plurality of magnetic sensors for selecting a magnetic sensor to be heat flashed, and means for selecting a channel of the magnetic sensor to be heat flashed from the list of channels. And an execution key for executing the heat flash of the magnetic sensor of the selected channel, and a cancel key for ending the display of the heat flash operation screen .

ADVANTAGE OF THE INVENTION According to this invention, the display apparatus of the magnetic field measuring device of the biological body with favorable operativity and visibility is provided.

  FIG. 1 shows a schematic configuration of an embodiment of a biomagnetic measuring apparatus in which the present invention is implemented.

  In the figure, the biomagnetism measuring apparatus is installed in the magnetic shield room 1 in order to remove the influence of environmental magnetic noise. A subject 2, which is a subject made of a living body, is measured while lying on the bed 3. The biological surface of the subject (a surface generally parallel to the chest wall in the case of the chest) is assumed to be substantially parallel to the surface of the bed 3, and this surface is the xy plane of the Cartesian coordinate system (x, y, z). It shall be parallel. The subject's chest is curved and inclined, but is substantially parallel for the sake of simplicity.

  Above the chest of the subject 2, a dewar 4 filled with a liquid He as a refrigerant is disposed. The dewar is connected to a superconducting quantum interference device (SQUID = Superconducting Quanttum Interference Device) and its SQUID. A plurality of magnetic sensors including a coil are accommodated. The liquid He is continuously replenished from the automatic replenishing device 5 outside the magnetic shield 1.

  The output of the magnetic sensor outputs a voltage having a specific relationship with the strength of the biomagnetic field generated from the subject 2 and detected by the detection coil (which can be considered as a magnetic flux density), and the output is FLL (Flux Locked loop) circuit 6 inputs. The FLL circuit 6 cancels the change of the biomagnetic field (biomagnetism) input to the SQUID via the feedback coil so as to keep the output of the SQUID constant (this is called magnetic field lock). By converting the current passed through the feedback coil into a voltage, a voltage output having a specific relationship with the change in the biomagnetic field signal can be obtained. Since the method of detecting via the feedback coil is taken as described above, a weak magnetic field can be detected with high sensitivity. The output voltage is input to an amplifier / filter / amplifier (AFA) 7, and the output is sampled, A / D converted, and taken into a computer 8.

The computer 8 comprises a personal computer, 8-1 is a display unit thereof, 8-2 is a keyboard, and 8-3 is a mouse. The mouse 8-3 is used to select a processing target by moving the cursor on the screen. This operation can also be performed by operating the keyboard. The input gain (I _gain ) and output gain (O _gain ) of the AFA 7 can be adjusted, and the AFA 7 is a low-pass filter (LPF) that allows a frequency signal below the first reference frequency to pass. A high-pass filter (HPF) that passes a frequency signal equal to or higher than the low second reference frequency and a notch filter (BEF) that cuts the commercial power supply frequency are included. The computer 8 can perform various processes, and the processing results can be displayed on the display unit 8-1. The computer 8 shown in FIG. 1 shows one embodiment, and is not limited to this. For example, a display with a touch panel may be used, or another coordinate pointing device such as a trackball or joystick may be used instead of the mouse. In some cases, a computer connected via a public telephone line may be used.

For example, a direct current SQUID is used as the SQUID. When an external magnetic field is applied to the SQUID, a DC bias current (I _bias ) is passed through the SQUID so that a corresponding voltage (V) is generated. When the external magnetic field is represented by magnetic flux Φ, a characteristic curve of V with respect to Φ, that is, a Φ-V characteristic curve is given by a periodic function. Prior to the measurement, the offset voltage (V _OFF ) of the FLL circuit 6 is adjusted to make the DC voltage of the Φ-V characteristic curve zero level. Further, the offset voltage (A _OFF ) of the AFA 7 is adjusted so that the output becomes zero when the input of the AFA 7 is zero.

  When a large magnetic field is applied to the SQUID from the outside, the magnetic field is trapped by the SQUID and the normal operation is not performed. In that case, the SQUID can be heated to a normal state once and then the heating can be stopped to remove the trapped magnetic field. In this case, the SQUID heating operation is referred to as heat flash.

  FIG. 2 shows an arrangement configuration of the magnetic sensor. The detection coil of the magnetic sensor has a coil for detecting a tangential component of the biomagnetic field (component substantially parallel to the biological surface, ie, the xy plane) and a normal component of the biomagnetic field (component orthogonal to the biological surface, ie, the xy plane). There is a coil to detect. As the coil for detecting the tangential component of the biomagnetic field, two coils whose coil surfaces are directed in the x direction and the y direction, respectively, and as the coil for detecting the normal component of the biomagnetic field, the coil surface is in the z direction. A coil that faces is used. A plurality of magnetic sensors 20-1 to 20-8, 211-1 to 21-8, 222-1 to 22-8, 233-1 to 23-8, 24-1 to 24-8, 25-1 to 25 As shown in FIG. 2, −8, 26-1 to 26-8, and 27-1 to 27-9 are arranged in a matrix on a living body surface, that is, a surface substantially parallel to the xy plane. Although the number of magnetic sensors may be arbitrary, in FIG. 2, since the matrix of magnetic sensors consists of 8 rows and 8 columns, the number of magnetic sensors is 8 × 8 = 64. As shown in FIG. 2, each magnetic sensor is arranged such that its longitudinal direction coincides with a direction (z direction) perpendicular to the biological surface, that is, the xy plane. In this embodiment, the bed surface and the XY plane of the sensor are parallel to each other. However, in order to increase the measurement accuracy, it is better to approach the body and the sensor can be tilted. However, since the human body that is the subject is constantly moving, if the human body is brought into close contact with the human body, this movement moves the detection unit, which makes it difficult to detect with high accuracy.

  FIG. 3 shows the configuration of each sensor that detects the normal component Bz of the biomagnetic field. In the figure, a coil made of a superconducting wire (Ni-Ti wire) is arranged so that its coil surface faces the z direction. This coil is composed of a combination of two coils 10 and 11 that are opposite to each other. The coil 10 closer to the subject 2 is a detection coil, and the far coil 11 is a reference coil that detects external magnetic field noise. The The external magnetic field noise is generated from a signal source farther than the subject, and therefore the noise signal is detected by both the detection coil 10 and the reference coil 11. On the other hand, the magnetic field signal from the subject is weak, and therefore the biomagnetic field signal is detected by the detection coil 10, but the reference coil 11 is hardly sensitive to the biomagnetic field signal. For this reason, since the detection coil 10 detects the biomagnetic field signal and the external magnetic field noise signal, and the reference coil 11 detects the external magnetic field noise signal, the S / N ratio can be obtained by taking the difference between the signals detected by the two coils. A high biomagnetic field can be measured. These coils are connected to the input coil of the SQUID via the superconducting wire of the mounting board on which the SQUID 12 is mounted, whereby the component Bz in the normal direction of the detected biomagnetic field signal is transmitted to the SQUID.

  FIG. 4 shows the configuration of a sensor that detects the tangential components Bx and By of the biomagnetic field of each of the magnetic sensors. In the figure, a planar coil is used in a sensor for detecting a biomagnetic field component in the tangential direction. That is, the detection coils 10 ′ and 10 ″ and the reference coils 11 ′ and 11 ″ are planar coils, which are respectively disposed on the first and second planes that are spaced apart from each other in the z direction. These coils are connected to the input coils of the mounting boards of SQUIDs 12 'and 12 "in the same way as for the normal component. The sensors 13 for detecting the Bx component and the By component detection are provided on two orthogonal surfaces of the quadrangular prism. A sensor 14 is attached to form a sensor capable of detecting the Bx component and the By component.

  As for the tangential components Bx and By, in addition to detecting them using the magnetic sensor shown in FIG. 4, the normal component Bz obtained by the magnetic sensor shown in FIG. Good. In this case, it is possible to detect and measure both the tangential components Bx and By and the normal component Bz with a single magnetic sensor.

  FIG. 5 shows the positional relationship between the magnetic sensor and the chest 30 which is the measurement part of the subject 2. The points shown represent the intersections between the rows and the columns on the matrix shown in FIG. 2, that is, the measurement points of the subject 2, that is, the measurement positions. Each of these measurement positions is also called a channel. As can be seen from the figure, in this embodiment, the height direction of the subject 2 is the y direction, and the lateral direction of the subject 2 is the x direction.

  FIG. 6 shows the measurement result of the biomagnetic field at each measurement position shown in FIG. This measurement result shows, for each corresponding channel in the matrix, a time-varying biomagnetic field waveform obtained by performing the above-described processing based on the signal detected by the magnetic sensor corresponding to each measurement position. Is. In this embodiment, since each channel is provided at a position where the magnetic field generated by the heart muscle can be detected, the waveform in FIG. 6 shows the magnetocardiogram waveform. A waveform obtained by measuring a magnetic field generated from the heart muscle is called a magnetocardiogram waveform. As shown in FIG. 6, when the measurement data measured for each channel is displayed corresponding to the position for each channel, this is called grid map display. FIG. 6 shows the waveform of the measurement result of the magnetocardiogram for a healthy person. Here, (a) shows the magnetocardiogram waveform of the tangential component Bx, (b) shows the magnetocardiogram waveform of the tangential component By, and (c) shows the magnetocardiogram waveform of the normal component Bz.

FIG. 7 shows a magnetocardiogram waveform of the tangential component Bx measured by focusing on a specific two channels for a healthy person. A solid line indicates a magnetocardiogram waveform of a certain channel, and a dotted line indicates a magnetocardiogram waveform of another channel. The time periods T ₁ when the heart ventricles are depolarized, that is, the time of each waveform peak in the QRS wave in the systole are shown as t _Q , t _R and t _S , respectively. Furthermore, the time zone of the T-wave is repolarization of the heart (diastole) is shown as T _2. When displaying the measured data, in addition to the grid map display, data for a single channel may be displayed for each row or column, or data for all channels or a plurality of channels may be displayed in an overlapping manner. You may make it do. The former is called single waveform display, and the latter is called superimposed waveform display.

The obtained magnetocardiogram waveform data can be averaged (averaged), or can be displayed as a result of creating an isomagnetic diagram, a time integration diagram, or the like. For example, referring to FIG. 7, the predetermined time (t _OFF ) goes back from the time when the rising portion of the QRS wave coincides with the threshold value S _L, and the predetermined time T from the time t ₁ that goes back. The data up to the time point t ₂ after the elapse of ₃ is added a predetermined number of times. This is the averaging, and the predetermined time T ₃ is called the averaging time, and t _OFF is called the offset time. The magnetocardiographic waveform data may be integrated over a predetermined time range. A map formed by connecting points (channels) having the same time integration value is called a time integration diagram. A map formed by connecting points having the same magnetocardiogram signal value is called an isomagnetic diagram. Since each channel is set coarsely, a figure more suitable for diagnosis can be created by drawing the isomagnetic line by linearly interpolating between each channel by setting the interval of the magnetic field lines, that is, the magnetic field strength difference in advance. be able to. Speaking of the magnetocardiogram waveform shown in FIG. 7, the time from the time point t ₁ to the QRS wave peak position time point (t _R time point) is called the propagation time, and the map made by connecting the points with the same propagation time is called. It is called a propagation time diagram. The setting level of the threshold S _L can be changed. The time point t _{1 is determined based on the} time point when the rising part of the QRS wave matches the threshold value S _L , but the time point when the falling part of the QRS wave matches the threshold value S _L is determined. You may decide on the basis. The t ₁ time point may further be determined based on the time point detected by detecting the peak position time point (t _R time point) of the QRS wave. The measured biomagnetic field signal is generated by an electrophysiological phenomenon in the living body, and its generation source is approximated by a current dipole model. The current dipole of the magnetic field generation source is synthesized and displayed on the isomagnetic diagram, and this is called magnetic field source display.

  A series of operations from registration of a subject to measurement of the registered subject's data and analysis of the measured data is performed while viewing the display screen displayed on the display 8-1. Is called. Therefore, before explaining the series of operations, the layout of the display screen will be described first.

  FIG. 8 shows a basic layout of the display screen displayed on the display 8-1 in FIG. The upper portion of the display screen is occupied by a title bar portion 801, a menu bar portion 802, and a toolbar portion 803 where icons are arranged in order from the top. Each of the above parts can be considered as a display area or an area. These arrangements are also displayed in common on the display screen for other processing purposes, for example, registration and reading of a subject, measurement of a magnetic field, and processing for analysis of measurement data. This increases the ease of use and reduces the time for measurement and processing.

  A central portion of the display screen is occupied by a subject information portion 804 arranged in order from left to right, an analysis data portion 805 on which analysis data such as a diagram and a waveform is displayed, and an operation region portion 806. The lower part is occupied by a status bar 807, which is composed of a message bar part 807-1 for displaying a guide message related to the next operation and a date / time display part 807-2 arranged on the right side. . The message bar unit 807-1 and the date / time display 807-2 may be one display area.

  In the display screen in this embodiment, the title bar unit 801 that always displays the name of the system at the top, the menu bar unit 802 that performs basic operations of the system, and the frequency of use in the menu bar unit 802 Since the tool bar 803 capable of high operation is arranged, the user does not need to search the operation area every time the display screen changes, and can always know the currently operating system by looking at the top of the display screen. . In addition, the upper part of the display screen is the first part to look at, as is apparent when a person reads a sentence. , Improving usability in a natural way. Further, the central portion of the display screen is provided with a large analysis data portion 805 that forms the main body of the display screen at the center thereof, thereby improving the legibility, and an operation area portion 806 specific to the display screen on the right side thereof. Since the arrangement is similar to the arrangement of the display screen and the operation unit in the right-hand operation, the operation can be performed without a sense of incongruity. Therefore, even if this display screen is adopted as a display screen with a touch panel, the right hand operating the operation area unit 806 does not interfere with the analysis data unit 805. Similarly, since the subject information unit 804 having only a confirmation function is provided on the left side of the analysis data unit 805, the operation can be performed while always confirming the patient. Moreover, since the left position is the farthest position in the right-hand operation, even if it is adopted for a display screen with a touch panel, the display visibility is not affected.

  Further, the analysis data portion 805 and the operation area portion 806 are replaced only when the subject list and the data list of the subject are displayed (FIG. 24). In the subject information section 804, when the subject list screen (FIG. 24) is displayed, information on the subject on which the cursor is placed in the subject list on the screen is always displayed, When analysis data such as a diagram or waveform is displayed in the analysis data section (FIGS. 25 to 34), information on the subject from whom the displayed analysis data is obtained is always displayed. This makes it possible to clearly know the relationship between the displayed analysis data and the subject from whom the analysis data was obtained. In this way, on the display screen of this system, like the menu bar unit 802, the subject information unit 804 is always displayed at a fixed position (left side) of the display screen. It is not necessary to search for the subject information area every time it changes, and it can be known by always looking at a predetermined position (left side) of the display screen.

  In the title bar portion, the name of the frame, specifically, the name “Multichannel MCG System” is displayed (FIGS. 24 to 34). Operation elements such as buttons and text boxes are arranged in the operation area portion. The menu bar part is a part for selecting an operation menu. The menus are “file (F)”, “edit (E)”, “list (L)”, “data measurement (Q)”, “data analysis (A)”. And “Help (H)”, arranged in the order of operations.

  FIG. 9 shows the contents of each operation menu in the menu section on the display screen, and the contents of these menus are displayed as pull-down menus by clicking the corresponding menu buttons. For this reason, when an operation menu is not required, only the keywords for calling up the menus are displayed in a compact manner on the menu bar, so a display area required for each operation such as an analysis data section and an operation area section is provided. Can be set widely. When an operation menu is required, the keywords arranged in accordance with the operation procedure can be selected and displayed by selecting from the menu bar portion. At this time, since the keywords are arranged in accordance with the arrangement of characters (from left to right), operation instructions can be given in a natural manner.

  The pull-down menu for “File (F)” opens a page layout dialog box (not shown), “Page Layout (U)” for setting the page layout, and “Preview (V)” for preview before printing. And “Print (P)” for printing data and “End of magnetocardiographic system (X)” for ending the Multichannel MCG System.

  The pull-down menu for “Edit (E)” includes an item “Delete (D)”. The measurement data of the subject in the subject list on the subject list screen (FIG. 24) is displayed in the data list on the screen, but the item “delete (D)” is in the data list. This is for deleting the data on which the cursor is placed, and the data must be selected in advance. When this menu is clicked, a confirmation dialog box will open asking if you are sure you want to delete it. If deletion is necessary, a button “OK” in the dialog box is clicked, and if it is desired to cancel the deletion, a button “Cancel” is clicked. By displaying and operating this confirmation dialog box, it is possible to reduce an erroneous operation of deleting the measurement data of the subject by mistake.

  The pull-down menu of “List (L)” includes items of “Registration (R)”, “List (L)”, “Delete (D)”, “Search (S)”, and “Release (X)”. When the “Register (R)” button in the pull-down menu is clicked, the subject registration dialog box shown in FIG. 10 is opened. This is used when registering data related to the subject. Items that can be registered are the date of registration, subject ID number, name, date of birth, height, weight, gender, disease These are classification and subject comments indicating the classification information. When the “Register” button in the dialog box is clicked, the data entered for registration is registered, all the input boxes are cleared and re-entry is possible, and the “Cancel” button is clicked. If so, all of the input boxes are cleared, and if the “Exit” button is clicked, the subject registration dialog box is closed.

  When “list (L)” in the pull-down menu is clicked, a subject list screen (FIG. 24) is displayed. Also, “Delete (D)” in the pull-down menu is used to delete the subject on which the cursor is placed in the subject list on the subject list screen (FIG. 24), and is clicked. Before the deletion, a confirmation dialog box for confirming whether or not the deletion can be performed is opened in the same manner as when “Delete (D)” in the pull-down menu is clicked. The “OK” button is clicked, and the “Cancel” button is clicked to cancel the deletion. When the subject is deleted, all the data in the data list regarding the subject is also deleted.

When “Search (S)” in the pull-down menu is clicked, a search dialog box shown in FIG. 11 is displayed. The subject and data are searched, and only the searched subject and data are displayed on the subject list screen. The subjects and data search targets are all subjects and all data. Data is retrieved by giving the subject name, registration date, gender, data type, measurement date, diagnosis result, comment, laboratory technician, position, etc. as keywords. A composite search combining a plurality of the above keywords can be performed. “Release (X)” in the pull-down menu is used to cancel the display of only the searched subject and data and display all the subjects and all data. The pull-down menu for “Data measurement (Q)” is “Adjustment value file (F)”, “Fully automatic adjustment (A)”, “V _OFF adjustment (V)”, “Manual adjustment (M)”, “Adjustment value file” (F) ”,“ Measurement panel (P) ”,“ Automatic waveform diagnosis (D) ”, and“ AFA offset adjustment (O) ”are included.

When “Adjustment File (F)” is clicked, a sub pull-down menu including “Open (O)”, “Overwrite (S)”, and “Save As (A)” is displayed. “Open (O)” in the sub pull-down menu displays the system adjustment screen (FIG. 34), opens the specified adjustment value file, and sets the system adjustment values, ie, I _bias and V _OFF to the system. Used. “Overwrite (S)” is used to open a confirmation dialog box and overwrite the current adjustment value over the currently opened adjustment value file. “Save As (A)” is used to save the current adjustment value data in a different adjustment value file with a different name.

When “Fully Automatic Adjustment (A)” in the pull-down menu is selected, a system adjustment screen (FIG. 34) is displayed, and the bias current I _bias and the offset voltage V _{OFF of the} FLL circuit 6 are set according to the flow of FIG. Adjusted automatically. When “V _OFF adjustment (V)” is selected, a system adjustment screen (FIG. 34) is displayed, and the offset voltage V _OFF of the FLL circuit 6 is automatically adjusted according to the flow of FIG. When “Manual Adjustment (M)” is selected, a manual adjustment dialog box shown in FIG. 12 is opened. The operator selects a channel using the scroll bar and the mouse, and changes the bias current I _bias and the offset voltage V _OFF . If there is no problem with the input value, the value is set by clicking the “OK” button. If the “Cancel” button is clicked, the changes are invalidated and the dialog box is closed.

When “Measurement Panel (P)” is clicked, a data measurement screen (FIG. 25) including a grid map is displayed. When “Automatic Waveform Diagnosis (D)” is clicked, an automatic diagnosis dialog box shown in FIG. 13 is opened. The automatic waveform diagnosis automatically checks the amplitude, median, and period of the Φ-V characteristic curve on the display screen of FIG. 34, and displays the latest state when displaying the Φ-V characteristic curve or when displaying the Φ-V characteristic curve. When updating, the channel outside the specified range is notified to the operator as being unsuitable for measurement. When a channel in an inappropriate state for measurement is detected, an error dialog box is opened and an error message is displayed to notify the operator. However, the Φ-V characteristic curve of the channel is displayed in a different color and is inappropriate. It may be shown that this is a state. When the minimum amplitude value is checked, it is assumed that the state where the difference between the maximum value and the minimum value in the Φ-V characteristic curve is smaller than the minimum amplitude value is inappropriate for measurement. When the median value is designated, the case where the absolute value of the average value of the maximum value and the minimum value is larger than the designated median value is not suitable for measurement. When the period is specified, measurement is not possible when the period of Φ in the Φ-V characteristic curve is outside the range specified by the first text box (lower limit) and the second text box (upper limit). Assume that it is in an appropriate state. To enable automatic diagnosis of minimum amplitude, median and period, click the check box on the left side of each item with the x mark displayed, and the desired value in the corresponding text box You can enter. The parameters of the automatic diagnosis input in this way are validated by pressing the “OK” button, and the dialog box is closed. When the “Cancel” button is pressed, the input parameters are invalid and the dialog box is closed. “AFA offset adjustment (O)” is used when adjusting the offset voltage A _OFF of the AFA 7, and when “AFA offset adjustment (O)” is clicked, a data measurement screen (see FIG. 25) is displayed.

  The pull-down menu for “Data Analysis (A)” includes “Averaging (A)”, “Single Waveform Display (W)”, “Overlapping Waveform Display (M)”, “Grid Map Display (G)”, “Isomagnetic” Diagram (B), Time integration diagram (T), Propagation time diagram (P), Magnetic field source display (S), Line mode (L), and Fill mode (F) including.

  When “Averaging (A)” is clicked, the averaging screen (FIG. 27) is displayed. When “Single Waveform Display (W)” is clicked, the single waveform display screen (FIG. 28) is displayed. When “Display (M)” is clicked, the superimposed waveform display screen (FIG. 29) is displayed, and when “Grid map display (G)” is clicked, the grid map display screen (FIG. 30) is displayed. A check mark (×) indicating that it has been selected is displayed. When the “isomagnetic diagram (B)” is clicked, the isomagnetic diagram screen (FIG. 31) is clicked. When the “time integral diagram (T)” is clicked, the time integral diagram screen (FIG. 32) is displayed. When “Propagation time diagram (P)” is clicked, a propagation time diagram screen (FIG. 33) is displayed, and a check mark (×) indicating selection is displayed on the left side of the menu. In addition, when “magnetic field source display (S)” is clicked, an inverted triangle mark is displayed on the left side of the menu, and a magnetic field source approximated by a current dipole is displayed in an overlapping manner when an isomagnetic diagram is displayed (see FIG. None). When the “Line mode (L)” is selected on the screen of isomagnetic diagram, time integration diagram, propagation time diagram, and magnetic field source display, the line spacing is displayed without filling, and “filling mode (F)”. When is selected, it is displayed in a state where the lines are filled. A check mark indicating selection is displayed on the left side of the menu to indicate the current mode.

  The pull-down menu for “Help (H)” includes “Contents (C)”, “Search by keyword (S)”, and “Version information (A)”. Used to search for and open the version dialog box.

  The tool bar 803 includes “subject registration” (808), “subject list” (809), “print” (810), “preview” (811), “system adjustment” (812), and “data measurement”. "(813)" and "Data analysis" (814) are arranged. Although not shown in the drawing, these are linked to menu functions, and the frequently used items of the pull-down menu items can be selected. That is, “subject registration” (808) is “registration (R)” of “list (L)”, and “subject list” (809) is “list (L)” of “list (L)”. “Print” (810) is “Print (P)” of “File (F)”, “Preview” (811) is “Preview (V)” of “File (F)”, and “System Adjustment”. (812) is “Manual adjustment (M)” of “Data measurement (Q)”, “Data measurement” (813) is “Measurement panel (P)” of “Data measurement (Q)”, and “Data analysis” "(814) corresponds to" grid map display (G) "of" data analysis (A) ". A menu linked to an icon in this way can be selected by simply clicking the icon. Therefore, operations that are frequently used can be easily performed by simply clicking on an icon adjacent to the analysis data section. Therefore, the operation is performed with icons that are easy to recognize in a shorter time than the operation of the menu bar section. be able to. The icon may be selected by the user, or may be automatically displayed on the toolbar unit 803 according to the usage frequency (number of times).

  Next, FIG. 14 to FIG. 14 show a series of operations from registration of a subject to data measurement of the registered subject and analysis of the measured data, including system adjustment operations. This will be described with reference to FIG.

  FIG. 16 shows the overall operation flow. When the power of the computer 8 is turned on (S-1), the operating system is started up and a program activation icon is displayed on the display unit 8-1. (S-2). When a multichannel MCG System program icon is selected from the icons (S-3), the subject list screen shown in FIG. 24 is displayed instead (S-4).

  In the system according to this embodiment, the subject list screen shown in FIG. 24 is displayed as the initial screen for system startup. This is because the relationship between the subject and the measurement or analysis data of the subject is extremely important, and this system is based on data management using subject information as a keyword. That is, measurement data and analysis data cannot be managed without subject information. For this reason, in this system, in the subject list screen, the subject is first specified when the subject is registered or registered, and then, in the case of a new measurement, the measurement is transferred to the measurement data, If there is, specify the target data. Prior to the subject list screen, a display screen waiting for the time of system startup may be provided, and a display screen serving as a table of contents for the system may be provided.

  The subject list screen shown in FIG. 24 will be described. The left side is occupied by the subject information section. In addition, a subject list is displayed at the upper part of the entire right side, and a data list is displayed at the lower part. Items displayed in the subject information section are the same as those described with reference to FIG. The items in the subject list are: ID (subject ID number), name, registration date (date of data registration), number of measurements (number of times data was measured), date of birth, age, height , Body weight, comments (comments about the subject), etc. The subject list can be scrolled with a vertical scroll bar, and the subject list items can be scrolled with a horizontal (horizontal) scroll bar. The row of the selected subject is highlighted.

  The data list items for the selected subject are: ID, type of data (raw or average), sampling interval (milliseconds of signal when data was measured) Sampling interval), sampling time (second unit), classification (disease classification information), Date and Time (date and time when data measurement was performed), comment (comment regarding data), and the like. The data list can be scrolled with a vertical scroll bar, and the data list item can be scrolled with a horizontal (horizontal) scroll bar. The selected row of data is highlighted.

  According to this subject list screen, one line of information of each subject is displayed in the subject list. Thereby, since the information of each subject arranged in the upper and lower directions can be clearly divided and the identification can be improved, for example, it is possible to reduce an erroneous operation of selecting another subject by mistake. it can. The information of each subject can be scrolled with a horizontal (horizontal) scroll bar, and the information of the selected subject is arranged vertically in the vertically long subject information section so that visibility is high. Will not be damaged. In this case, the visibility may be further improved by allowing the items in the data list of each subject to move forward and backward (left and right). Furthermore, by displaying one line of information for each subject, a large number of subjects can be viewed at one time, so that the number of times of scrolling with the vertical scroll bar can be reduced. Further, data related to the target subject can be displayed in the lower data list by a simple operation of placing the cursor on the subject list to be selected from the subject list and clicking. In addition, since the subject list and the data list are arranged one above the other, the eye movement can be reduced, and the relevance can be easily recognized. In addition, the size of the data list can be changed freely by a simple operation of moving and dragging the cursor to the top of the area, so the size can be set according to the number of lists in the data list. can do.

  In step S-5, a desired subject row is selected from the subject list on the subject list screen. In the case of the averaging process described later, a raw data row in the data list is always selected. The subsequent flow is branched into four by the menu (S-6). According to one of the branches, a sub-menu “End of magnetocardiogram system (X)” in the menu “File (F)” is selected. In this case, an end process such as closing a window is performed (S-7). As a result, the system is shut down (S-8). Thereafter, the power source of the computer 18 is turned off (S-9), and all the processing is completed.

  According to the remainder of the branching, averaging processing (S-10), data analysis (S-11), and data measurement (S-12) are performed. The averaging process can be executed by selecting a submenu “Averaging (A)” in a menu “Data Analysis (A)”. In addition, data analysis includes “single waveform display (W)”, “overlapping waveform display (M)”, “grid map display (G)”, “isomagnetic diagram (B) in the menu“ data analysis (A) ”. ) ”,“ Time integration diagram (T) ”,“ Propagation time diagram (P) ”, and“ Magnetic field source display (S) ”submenus can be selected. Furthermore, data measurement can be performed by selecting a submenu called “Measurement Panel (P)” in a menu called “Data Measurement (Q)”. After steps 10, 11, and 12, the flow returns to step S-4. Details of the subject selection in step S-5, the averaging process in step S-10, the data analysis in step S-11, and the data analysis in step S-12 will be described below with reference to FIGS. Will be described in more detail.

  FIG. 17 shows a flow of subject selection in step S-5 of FIG. In the case of subject selection, the flow is branched into four by menu selection or subject selection. One of the branches is when the subject selection is completed by selecting and selecting the subject (S-5-1). According to another branch, the submenu “Search (S)” of the menu “List (L)” is selected. Thus, the search dialog box shown in FIG. 11 is opened (S-5-2), and the subject search condition is input using this dialog box (S-5-3). Thus, the subject is searched (S-5-4), and based on this, the display content of the subject list on the subject list screen shown in FIG. 24 is changed (S-5-5). . According to yet another branch, the submenu “Release (X)” of the menu “List (L)” is selected. In this case, the selected subject is returned to the all subject list (S-5-6), and the display content of the subject list is changed (S-5-5). According to the remaining one of the branches, the submenu “Register (R)” of the menu “List (L)” is selected. In this case, the subject registration dialog box shown in FIG. 10 is opened (S-5-7), and subject information is input (S-5-8). About these steps, the input completion is judged until the input of all subjects is completed (S-5-9), and when the input is completed, the subject list is updated (S-5). -5).

  In this embodiment, except for inputting characters such as the name and address of the subject, a plurality of input data or operation instructions to be input are displayed by displaying a pull-down menu on the display screen, and from among the selection targets An input operation is performed by designating a specific target with a mouse. As a result, almost all operations can be performed by operating the mouse, so that it is possible to provide a comfortable operating environment for an operator who is unfamiliar with the keyboard and to shorten the input / operation time. As the plurality of selection targets in the pull-down menu, selection targets that can be input / operated in this device or its input / operation state are set and displayed in advance, so that erroneous input / incorrect operation can be reduced. Further, in this embodiment, since the cursor can be placed on the input area and input can be performed via the keyboard, the degree of freedom of input by the operator is ensured. In this embodiment, it is assumed that characters are input with a keyboard. However, a keyboard dialog may be displayed during input, and this may be input by operating with a mouse. Furthermore, a handwriting input dialog may be displayed and handwriting input may be performed by a mouse operation. Furthermore, the display unit may be provided with a touch panel, and input / operation may be operated on the screen via a fingertip or an input pen. As a result, the operability of input / operation can be significantly improved.

  FIG. 18 shows a flow of data measurement in step S-12 in FIG. First, a grid map of the magnetocardiogram waveform is displayed as an initial screen as shown in FIG. 25 (S-12-1). In the figure, in the operation area section, operations for channel selection, waveform monitor ON / OFF, FLL circuit 6 lock-unlock, automatic adjustment of the offset voltage of AFA 7 and heat flash can be performed, respectively. Signal sampling condition setting, waveform display scale setting, and AFA parameter setting are possible.

  The channel consists of 64 channels of 8.times.8, and all channels can be selected by clicking the "Select All Channels" button or by dragging the channel matrix across the diagonal. Further, if the channel matrix is dragged in units of rows or columns, channels can be selected in units of rows or columns. In any case, the magnetocardiogram waveform of the selected channel is displayed in the analysis data portion. In the case of selection in units of rows or columns, it is displayed as shown in FIG. In this case, the selected waveform is enlarged and displayed on the full scale with respect to the time axis. That is, when all 64 channels are selected, as shown in FIG. 25, the analysis data part is divided into upper, lower, left and right (grid) to give priority to the display of all channels, and the selection is made in units of rows or columns. As shown in FIG. 26, the analysis data part is divided into upper and lower parts and the form of a familiar graph in which the time axis is set to the left and right is used to make the display form prioritizing visibility.

  For waveform monitoring, when the “ON” button is pressed, for example, signal acquisition and waveform updating are repeated every specified time between 0.5 sec and 2 sec, and the subject's magnetocardiogram signal is monitored. The When the “OFF” button is pressed, the waveform update is stopped. With respect to FLL, by clicking the “Lock” button or the “Unlock” button, it is possible to perform magnetic field lock on 64 SQUID sensors and to release the lock. In this case, if one button is pressed, the state is maintained until the other button is pressed. Thereby, the state of malfunction which is not selected is avoided.

If the “AFA offset adjustment” button is clicked, the offset voltage is automatically adjusted. If the “heat flash” button is clicked, a heat flash operation dialog box shown in FIG. 14 is opened. If a channel is selected with the mouse or the arrow key and the “ execute ” button is clicked, the heat flash operation is executed for the SQUID of the selected channel. If the “Cancel” button is pressed, the dialog box is closed and the process ends.

  With respect to the sampling time (measurement time) and interval, clicking a corresponding text box with an inverted triangle mark opens a pull-down menu of selectable numerical values, from which a desired number can be selected. The selectable numbers are, for example, 1 sec, 5 sec, 10 sec, 30 sec, 1 min and 2 min for the time, and for the interval, for example, 0.1 msec, 0.5 msec, 1.0 msec, 2.0 msec, 4.0 msec, 0.0 msec and 10.0 msec. The time may be selected from about 1 sec to about 24 h as necessary. “Time” in the “Scale” box means a time scale in msec, that is, a horizontal scale, and “Signal” means a scale of an A / D converted signal, that is, a vertical scale. For these, as well as the selection of the sampling time and interval, a desired numerical value is selected from a pull-down menu that is opened by clicking the corresponding text box.

  The AFA parameters include an input gain Igain, an output gain Ogain, a low-pass filter (LPF) frequency (reference frequency), a notch filter (BEF) frequency, and a high-pass filter frequency (reference frequency). Similarly, for these, a desired number or letter is selected from a pull-down menu that is opened by clicking the corresponding text box. The numbers or letters are for example 1, 2, 5, 10, 20, 50, 100, 200, 500 and 1000 for Igain, for example 1, 10 and 100 for Ogain, for example 30 Hz for LPF, 50 Hz, 80 Hz, 100 Hz, 200 Hz, 400 Hz and 1 kHz, Off for BEF, 50 Hz and 60 Hz, and for HPF eg 0.05 Hz, 0.1 Hz and Thru. It is. These may be input from a keyboard instead of selection.

  In addition to the 64 channels, for example, 16 auxiliary channels may be prepared in addition to the 64 channels, and for example, an electrocardiographic waveform may be obtained from the auxiliary channels. The waveform of the tenth channel as a reference channel is displayed at the bottom of FIG. 25. This is an electrocardiographic waveform obtained from the tenth channel among the auxiliary channels. The magnetocardiogram waveform generally contains magnetic noise, while the electrocardiogram waveform does not contain such noise. Therefore, by comparing the displayed magnetocardiogram waveform with the electrocardiogram waveform of the reference channel, information on whether the magnetocardiogram waveform includes magnetic noise can be obtained. Of course, the electrocardiogram waveform may be obtained from any channel of the regular 64 channels, not the auxiliary channel. In addition to an electrocardiogram waveform, an electroencephalogram, a blood flow waveform, a blood pressure waveform, or the like may be used. Furthermore, the electrocardiogram waveform of the pregnant woman and the magnetocardiogram waveform of the fetus may be compared. Further, as the reference waveform, not only a reference waveform for one channel but also a reference waveform for a plurality of channels may be displayed. Furthermore, the reference channel may be used to input not only a signal from a living body but also various control signals for the purpose of maintenance and the like.

  Returning to the flow of FIG. 18, in step S-12-2, the monitor channel is selected as described above (S-12-2), and when the FLL lock button is pressed, the magnetic fields of all SQUIDs are locked. (Step S-12-3). In this state, sampling time and signal, which are measurement parameters, and AFA parameters are set (step S-12-4). For this setting, this setting can be omitted from the next time by using the set condition. As a result, it is not necessary to set the condition every time, so the setting time can be shortened. The setting condition may be recorded and recalled by giving a name or the like.

  When the “Start” button in the “Measurement” box is pressed, the measurement is started. As shown in FIG. 15, “Measurement in progress” is displayed and a progress bar indicating the progress of the measurement is displayed (Step S). -12-5). In the progress bar of this embodiment, the bar extends from the left to the right in the progress of the processing progress in the bar graph format. However, it is only necessary to know the current processing progress when the entire processing content (time) is 100, for example. Therefore, a pie chart or the like may be used. In addition, the progress bar is displayed with the measurement screen remaining around the predetermined position of the measurement screen. Thereby, since the content of the display screen does not change greatly, it is possible to reduce erroneous operations.

  When the measurement is started, the displayed signal waveform is fixed as it is, and the progress bar is displayed on the fixed display screen. The update of the progress bar is repeated, for example, every second until the set time ends (S-12-6). When the “Stop” button in the “Measurement” box is pressed, the measurement is stopped. When the measurement is completed, the screen shown in FIG. 26 is displayed and the waveform is confirmed (S-12-7). Thereafter, the necessity of storage of the data is determined (S-12-8), and when the storage is necessary, the menu "File (F)"-"Save (S)" is selected, the signal is stored, It is added to the data list of the subject (S-12-9). Thereafter, it is determined whether or not the measurement is necessary again including the case where the storage is not necessary (S-12-10). If necessary, the above steps are repeated, and if not necessary, all the steps of the data measurement are ended. In that case, the menu selection is made so that the screen display becomes the display of FIG. FIG. 26 shows an example in which the channel in the second row is selected as the channel.

  In FIG. 26, there is a scroll bar 262 to which a scroll box 261 moves at the bottom of the analysis data portion. The scroll box 261 is movable between the left and right ends of the scroll bar 262, and the width w of the scroll box represents a time scale. The time width between the left and right ends of the scroll bar 262 represents the measurement time. Therefore, the displayed waveform is a part of the waveform generated during the measurement time and an enlarged waveform corresponding to the time scale w of the scroll box 261. It is. As a result, the operator indicates how long (the width of the scroll box 261) the waveform currently displayed in the analysis data portion is within the measurement time (the width of the scroll bar 262), and the waveform indicates the measurement time. Among them, it is possible to grasp with the human eye whether the first half or the second half is shown, so that the visibility can be improved. In addition, since the position of the scroll box 261 and the waveform of the analysis data portion are linked, the display area of the analysis data portion is moved for a predetermined time by moving the cursor while dragging the cursor to the scroll box 261. You may make it look at the waveform. In this way, the contents of measurement can be confirmed in detail by handling the scroll bar 262 in a table of contents, such as simply confirming the waveform for a predetermined time.

  FIG. 19 shows the flow of the averaging process in step S-10 of FIG. In the averaging process, in order to remove the noise of each data measured in each channel, the average value is calculated by adding for each channel. In order to set a reference time for the averaging process for each channel, the following process is performed, and the averaging process for each channel is executed.

  First, raw data of a designated subject is read (S-10-1). This is performed by selecting a row in which the “data type” in the list data in FIG. 24 is raw data. As a result, the magnetocardiogram waveform of the channel in the first column shown in FIG. 27 is displayed as the initial display (S-10-2). Next, the display channel is selected (S-10-3). FIG. 27 shows an example in which the channel in the second column is selected. Thereafter, a setting channel is designated (S-10-4). This is done by clicking the “channel” text box in the “averaging condition” box in the operation area or by clicking the area displaying the waveform of the desired channel with the mouse. In this case, clicking the triangle button in the text box increases the channel number, and clicking the inverted triangle button decreases the channel number. FIG. 27 shows an example in which the designated channel is the channel in the second column and the second row. By this channel designation, a channel serving as a reference time for the averaging process is specified. In specifying this channel, it is preferable to select a channel having the most typical or easy-to-understand waveform. If there is no channel with a good waveform in the selected row or column, it is possible to start again from step (S-10-3).

  When one channel of the analysis data portion is specified, a threshold cursor 271 is displayed at the designated channel position as shown in FIG. As a result, the designated channel can be visually confirmed. In FIG. 27, three slider cursors 273 to 275 that can move in the left-right direction are displayed at the top of the analysis data portion 805. These are automatically displayed at the same time as the display screen of FIG. 27 is displayed. The

  In step S-10-5, the threshold, offset time, and averaging time, which are the averaging conditions, are set by clicking the corresponding text box in the box “Averaging Condition”. Click the triangle button to increase the number, and click the inverted triangle button to decrease the number. The threshold is set by selecting a number representing the threshold in the “Threshold” text box. As a result, the threshold cursor 271 automatically moves to a position corresponding to the number. In this case, the movement position can be clearly confirmed by the cursor line. The change (selection) of the number representing the threshold value in the “Threshold” text box and the movement of the threshold cursor 271 are linked to each other, and therefore the threshold value can also be set by moving the threshold cursor 271. Is possible. The slider cursor 273 indicates a position (reference time) where the rising edge of the waveform coincides with the threshold set by the slider cursor 271. The position indicated can be clearly confirmed by the cursor line. The slider cursor 273 moves following the reference time point so as to coincide with the reference time point that changes according to the change of the threshold value. When a number representing the offset time is selected in the “Offset” text box and a number representing the averaging time is selected in the “Time” text box, the slider cursors 274 and 275 move to corresponding positions. The moving position in that case can be clearly confirmed by the cursor line of those slider cursors. The movement of the slider cursors 274 and 275 is linked to the selection of numbers in the “Offset” text box and the “Time” text box. For this reason, the offset time and the averaging time can also be set by moving the slider cursor.

  In step S-10-6, whether the averaging should be performed automatically or manually as the averaging mode is set (S-10-7). Thereafter, when the “Setting” button is clicked (S-10-8), an addition process is performed. Clicking the “Cancel” button cancels all averaging conditions. As the addition processing, the time t (reference time point) exceeding the threshold value is searched for in each channel (S-10-9), and then the waveform is displayed around the time t (that is, the time point t is displayed on the screen). The waveform from t-50 msec to t + 50 msec is displayed so as to be positioned at the center) (S-10-10), and it is determined whether or not cancel is selected in the manual mode (S-10-11). If not selected, waveform addition is executed (S-10-12). The steps from Step S-10-9 to Step S-10-12 are repeated for each channel by the number of times of addition, and then the added data is divided by the number of times of addition (S-10-13), and the averaging process is performed. Ends.

  In this way, on the display screen of the averaging process shown in FIG. 27, the conditions of the averaging process can be input / operated from both the operation area part and the analysis data part 805. It is possible to provide the operator with various setting methods, such as setting conditions in the analysis data portion and setting detailed values in the operation area portion, and shorten the time for setting conditions. In particular, in this embodiment, by designating a specific channel from among a plurality of channels of the analysis data portion 805 via a cursor, it can be used as a reference channel for averaging processing. Is improved. In addition, visual recognition is possible by displaying a threshold cursor or slider cursor near the designated channel. Furthermore, the averaging process conditions can be entered / operated with the threshold cursor and slider cursor located near the channel, reducing the operator's line of sight and visually matching the waveform display. Therefore, operability can be improved by reducing erroneous operations. These setting conditions, for example, the latest setting conditions may be stored and displayed as the next setting conditions, or each setting condition may be stored with a name and recalled.

  FIG. 20 shows a data analysis flow in step S-11 of FIG. Data analysis is to display various types of waveforms and diagrams to obtain information necessary for diagnosis. By selecting the menu in FIG. 9, various types of waveforms and diagrams can be selectively displayed. Can be displayed. That is, if “single waveform display (W)” of “data analysis (A)” is selected, the single waveform screen shown in FIG. 28 is (S-11-2), and “data analysis (A)” “ If "superimposed waveform display (M)" is selected, the superimposed waveform screen shown in FIG. 29 is (S-11-3), and if "grid map display (G)" of "data analysis (A)" is selected, FIG. If the grid map waveform screen shown in FIG. 30 is (S-11-4) and “isomagnetic diagram (B)” of “data analysis (A)” is selected, the isomagnetic diagram screen shown in FIG. S-11-5) If “Propagation time diagram (P)” of “Data analysis (A)” is selected, a propagation time diagram screen shown in FIG. 32 is displayed (S-11-6), and “Data analysis ( A) "" Time integral diagram (T) "is selected, the time integral diagram screen shown in FIG. 33 is displayed (S-11-7). Is, also, the system is completed by selecting the "File (F)" and "End of magnetocardiogram system (X)" of.

  In each screen, if a radio button (circular button in the drawing) in the operation area is clicked, the waveform or diagram screen designated by the click is displayed instead. In FIG. 20, the branch portion is not “branch by menu” but “branch by menu or radio button”. Therefore, according to this embodiment, various analysis data can be obtained by simply clicking on the radio button in the operation area without selecting the menu of FIG. 9, so that the operation time can be shortened. Operability can be improved by reducing erroneous operations.

  28 to 30, the magnetic flux density in the “scale” box is the plus and minus full scale values (unit: picotesla (pT)) with respect to the zero level, and the value is It is selected in the pull-down menu that is opened by clicking the triangle button in the text box. 28 to 33, by clicking a radio box in the “display component” box, the waveform of the normal component or the waveform of the tangential component can be selected and displayed on the screen.

  In FIG. 28, the waveform of each channel selected as a channel is displayed with the left end of the analysis data portion aligned with the offset time. According to this analysis data, it is possible to compare the shape and size of the waveform of each channel arranged and displayed in the analysis data section vertically. Similarly, in FIG. 29, the waveforms arranged in the vertical direction in FIG. 28 are displayed in an overlapping manner, and the shapes and sizes of the waveforms can be compared. In FIG. 30, all channels are displayed with reference to the offset time as in FIGS. Therefore, the operator can select and analyze the number of channels as necessary.

  In FIG. 31, an elongated magnetic field strength index box 310 is arranged at the right end of the analysis data portion. The magnetic field strength index box is divided into 12 sections having different colors. This is to improve the visual (color) recognizability by distinguishing the intensity range of the magnetic field indicated by each island pattern on the isomagnetic diagram screen shown in FIG. 31 by the type of color. It is. That is, the center position 311 in the longitudinal direction of the magnetic field strength index box 310 is a position where the magnetic field strength is zero, and the sections above the center position are referred to as the first to sixth sections in order from the center position. For example, the first section has a magnetic field strength range of 0 to 2 pT, the second section has a magnetic field strength range of 2 to 4 pT, the third section has a magnetic field strength range of 4 to 6 pT, and the fourth section has a magnetic field strength range of 6 to 8 pT. The fifth section corresponds to a magnetic field strength range of 8 to 10 pT, and the sixth section corresponds to a magnetic field strength range of 10 to 12 pT. The same applies to the section below the center position. However, the section above the center position represents the magnetic field intensity in the plus direction, and the section below the field represents the magnetic field intensity in the minus direction. The isomagnetic diagram shown in FIG. 31 is displayed in different colors according to the magnetic field strength in accordance with the definition of the correspondence relationship between the magnetic field strength range and the color in the magnetic field strength indicator box 310. The color may be such that the plus side of the magnetic field strength is warm, the minus side is cold, and the center is yellow. Thereby, since the strength of a magnetic field can be recognized chromatically, visibility can be improved. Moreover, according to this embodiment, since the magnetic field strength index box 310 is provided in the vicinity of the analysis data section, the color to be compared, that is, the color attached to the map and the predetermined color of the magnetic field strength index box 310 are displayed. Since the eye movement can be confirmed while comparing without greatly moving, the relationship between the level of the magnetic field strength and the color can be clearly determined. In this embodiment, the magnetic field strength index box 310 is provided at the right end of the analysis data part, but it may be in the vicinity of the analysis data part, for example, at the upper part, the lower part, or the left side.

  In FIG. 31, “number of maps” in the “reconstruction parameter” box indicates the number of displayed isomagnetic diagrams, and “maximum value” corresponds to both ends of the magnetic field strength index box 310. The magnetic field strength “interval” means a magnetic field range corresponding to the length of each section in the magnetic field strength indicator box 310. The value can be selected by clicking the triangle or inverted triangle button in the corresponding text box.

  The electrocardiographic waveform of the reference channel and two map time selection cursors 311 and 312 are displayed at the bottom of the analysis data portion. A dividing line having the same interval is displayed between the two map time selection cursors 311 and 312. The number of lines coincides with the number of maps selected by selecting the number of maps. Also, the two map time selection cursors 311 and 312 can be moved independently in the left-right direction, and if the distance between the cursors changes due to the movement, the interval between the dividing lines also changes. Are always equally spaced. Of course, each dividing line may be provided with a cursor and set individually. In FIG. 31, the number of displayed isomagnetic diagrams is 16, but these diagrams are diagrams at the time when the dividing line on the electrocardiogram waveform is located. The time is also displayed so that you can see when the map is current.

  As a result, as described with reference to FIG. 26, the operator can determine how much the map currently displayed in the analysis data portion is within the analysis time (the width of the electrocardiogram waveform) (two cursors 311 and 312). And the range indicated by the map can be grasped at a glance in the analysis time, so that the visibility can be improved. Further, since the range indicated by the map can be set by simply moving two cursors with a mouse, the operation is easy. Furthermore, if the interval between the dividing lines is set freely, various analysis environments can be provided to the operator, such as making a questionable part dense and making another part sparse.

  In addition, when a check mark is displayed by clicking the “current direction” check box in the operation area, an arrow is displayed on the isomagnetic diagram. The isomagnetic diagram on which this arrow is displayed is called an arrow map (not shown). Regarding the arrow, the position indicates the channel position (magnetic sensor position), the length indicates the magnetic field strength, and the direction indicates the current direction when the magnetic field direction is converted into the current direction.

In FIG. 32, the starting position of the propagation time (at time t _{1 in} FIG. 7) can be changed by changing the position of the cursor 321 that moves on the reference waveform, and the cursor 321 can be changed by moving the cursor over the mouse. It is possible by using and dragging.

  In FIG. 33, two time integration diagrams and one difference diagram are displayed. The “difference display” of the propagation time diagram can be easily displayed by clicking the check box and displaying a check mark. When “difference display” is checked, four cursors 331 to 334 appear on the reference waveform, and two time integration diagrams are displayed on the upper left and right as shown in the figure, and a difference diagram is displayed on the lower left side. The two time integration diagrams are based on the value obtained by integrating the magnetocardiogram waveform over the time range of 100 msec to 140 msec and 180 msec to 240 msec set using the cursors 331 and 332 and the cursors 333 and 334 on the reference waveform, respectively. Thus, the respective time ranges can be changed by dragging the cursors 331 and 332 and the cursors 333 and 334 with the mouse, respectively. The difference diagram represents the difference between the two time integral diagrams. When there is no check mark, only two cursors (for example, cursors 331 and 332) appear for the cursor, and only one time integration diagram is displayed for the time integration diagram. Of course, the integration time can be changed by changing the position of the cursor. As described above, according to this embodiment, by clicking the check mark in the “difference display”, two sets of cursors for prompting the next operation are displayed. In addition, since the time range can be easily set by moving the two sets of cursors with the mouse, the operability can be improved.

FIG. 21 shows the flow of system adjustment. The flow is branched into five by menu selection (S-15). In this case, the currently displayed data is stored as it is (S-13), and the Φ-V characteristic curve shown in FIG. 34 is displayed (S-14). When “Fully automatic adjustment (A)” of “Data measurement (Q)” is selected, adjustment values of I _bias and V _OFF are automatically calculated for the designated channel (S-16) The calculation is described later. The calculated adjustment value is set in the FLL circuit (S-17), and the flow returns to step S-14.

When “V _OFF adjustment (V)” of “Data measurement (Q)” is selected, V _oFF is calculated for the designated channel (S−18) (the calculation of V _OFF will be described later). Advances to step S-17 described above. When “Manual adjustment (M)” of “Data measurement (Q)” is selected, the manual adjustment dialog box shown in FIG. 12 is opened (S-19). When the operator inputs adjustment values of I _bias and V _OFF for each channel, the input adjustment values are accepted (S-20), and the “OK” button in the dialog box is pressed, and the adjustment values are transferred to the FLL circuit. (S-21). The dialog box is thereby closed (S-22), and the flow proceeds to step S-17.

  When “Adjustment value file (F)” of “Data measurement (Q)” is selected, the flow is further branched into two by the sub pull-down menu (S-22). That is, by selecting “Open (O)” from the sub pull-down menu, the operator is inquired about the file, and the operator inputs the file including the contents of FIG. 11 (S-23). The contents of the adjustment value file are set in the FLL circuit (S-24). Further, by selecting "Data measurement (Q)"-"Adjustment value file (F)"-"Overwrite" or "Save as (A)", the same operation as Step S-23 is performed. (S-25) The adjustment value can be written into the adjustment value file (S-26).

FIG. 22 shows a flow of automatic calculation in step S-16 of FIG.
S-155-1: In the case of full automatic adjustment, the following processing is performed for each SQUID channel one channel at a time. Let ch be the channel being processed.
S-15-2: The calculated bias current and offset voltage are held in memories named IBIAS and VOFF. IBIAS and VOFF can hold values as many as the number of channels, and the initial values are all zero. Let ΔV be the temporarily stored amplitude of the Φ-V characteristic curve.

S-15-3: For each channel ch, the bias current I _b is changed (scanned) in steps of ΔI _bias from 0 to I _bias specified in the “scan parameter” box in FIG. Let I _{bias at} which the amplitude ΔV of the curve is the largest be the optimum bias current IBIAS (ch) of the channel ch.

S-15-4~8: between the bias current 0 to I _b, the amplitude ΔV of [Phi-V characteristic curve can be determined by the following process. An external magnetic field [Phi given to the channel ch SQUID varied in ΔΦ steps from 0 to [Phi _ext specified by the "scan parameters" box in Figure 34 (scan to) airport, save the A / D converted signal Then, the maximum value M _max and the minimum value V _min of the signal are obtained.

S-15-9 to 10: Here, if the difference between the maximum value M _max and the minimum value V _min is larger than ΔV, the value of IBIAS (ch) is I _bias and the value of VOFF (ch) is the maximum value M _max . ΔV is replaced with the difference between the maximum value V _max and the minimum value V _min by averaging the minimum values V _min . If ΔV is larger than the difference between the maximum value M _max and the minimum value V _min , the previous value is retained.

S-15-11: above processing bias current I _b is IBIAS when repeated until the _{I bias (ch), VOFF (} ch) is the optimum bias current and offset voltage of the SQUID channel ch.
S-15-12: Further, the above-described processing is executed for all the SQUID channels to complete the fully automatic adjustment.

FIG. 23 shows a VOFF adjustment flow in step 18 of FIG.
S-18-1: In the case of V _OFF adjustment, the following processing is performed channel by channel for all SQUID channels.
S-18-2~6: by changing the external magnetic field [Phi given to the channel ch SQUID from 0 by "scanning parameters" ΔΦ steps until [Phi _ext specified in box 34 (scanned by) go, A The difference between the maximum value V _max and the minimum value V _min of the / D converted signal is obtained.

S-18-7: optimum offset voltage VOFF of the SQUID channel ch (ch) is calculated as the difference between the maximum value V _max and the minimum value V _min.
S-18-8: The V _OFF adjustment is completed by executing the above processing for all the SQUID channels.

It is a schematic block diagram of one Example of the biomagnetic field measuring apparatus with which this invention is implemented. It is a perspective view which shows the arrangement configuration of the magnetic sensor used for the biomagnetic field measuring apparatus of FIG. It is a perspective view of the magnetic sensor single-piece | unit which detects the normal line component of a magnetic field used in the biomagnetic field measuring apparatus of FIG. It is a perspective view of the magnetic sensor single-piece | unit which detects the normal line component of a magnetic field used in the biomagnetic field measuring apparatus of FIG. It is a figure which shows the positional relationship of the magnetic sensor in the biomagnetic field measuring apparatus of FIG. FIG. 2 is a time waveform diagram of each component of a healthy subject's biomagnetic field (cardiac magnetism) measured by each magnetic sensor in the biomagnetic field measurement apparatus of FIG. 1. FIG. 2 is a diagram illustrating a time waveform of a tangential component of a specific two-channel magnetocardiogram measured for a healthy person in the biomagnetic field measurement apparatus of FIG. 1. FIG. 2 is a diagram showing a basic layout of a display screen displayed on a display unit in the biomagnetic field measurement apparatus of FIG. 1. In the biomagnetic field measurement apparatus of FIG. 1, it is a figure which shows the operation menu in the menu bar part of the display screen displayed on a display part. In the biomagnetic field measurement apparatus of FIG. 1, a subject registration dialog box that is opened when “list (L)”-“registration (R)” is selected as the operation menu in the display screen displayed on the display unit. It is a figure which shows the content. In the biomagnetic field measurement apparatus of FIG. 1, the contents of a search dialog box that is opened when “list (L)”-“search (S)” is selected as the operation menu in the display screen displayed on the display unit are shown. FIG. In the biomagnetic field measurement apparatus of FIG. 1, a manual adjustment dialog box that is opened when “data measurement (Q)”-“manual adjustment (M)” is selected as the operation menu in the display screen displayed on the display unit. It is a figure which shows the content. In the biomagnetic field measurement apparatus of FIG. 1, an automatic diagnosis dialog box that is opened when “data measurement (Q)”-“measurement panel (P)” is selected as the operation menu in the display screen displayed on the display unit. It is a figure which shows the content. In the biomagnetic field measurement apparatus of FIG. 1, when the “heat flash” button is pressed when the display screen of FIG. 25 or FIG. 26 is displayed on the display unit, the contents of the heat flash operation dialog box opened It is. In the biomagnetic field measurement apparatus of FIG. 1, it is a figure which shows the measurement progress bar displayed on a display part during measurement. It is a figure which shows the flow of the whole operation performed in the biomagnetic field measuring apparatus of FIG. It is a figure which shows the subject selection flow in the subject selection step in the operation flow of FIG. It is a figure which shows the flow of the data measurement in the data measurement step in the operation flow of FIG. It is a figure which shows the flow of the averaging process in the averaging process step in the operation flow of FIG. It is a figure which shows the flow of the data analysis in the data analysis step in the operation flow of FIG. It is a figure which shows the flow of the system adjustment performed in the biomagnetic field measuring apparatus of FIG. It is a figure which shows the flow of the automatic calculation in the automatic calculation step in the system adjustment flow of FIG. It is a figure which shows the _VOFF adjustment flow in the _VOFF adjustment step in the system adjustment flow of FIG. It is a figure which shows the subject list screen displayed on the display part of the biomagnetic field measuring apparatus of FIG. It is a figure which shows the data measurement screen displayed on the display part of the biomagnetic field measuring apparatus of FIG. It is a figure which shows the waveform confirmation screen displayed when a measurement is complete | finished in the display part of the biomagnetic field measuring apparatus of FIG. It is a figure which shows the averaging screen displayed on the display part of the biomagnetic field measuring apparatus of FIG. It is a figure which shows the single waveform display screen displayed on the display part of the biomagnetic field measuring apparatus of FIG. It is a figure which shows the overlapping waveform display screen displayed on the display part of the biomagnetic field measuring apparatus of FIG. It is a figure which shows the grid map display screen displayed on the display part of the biomagnetic field measuring apparatus of FIG. It is a figure which shows the isomagnetic diagram display screen displayed on the display part of the biomagnetic field measuring apparatus of FIG. It is a figure which shows the propagation time figure display screen displayed on the display part of the biomagnetic field measuring apparatus of FIG. It is a figure which shows the time integral figure display screen displayed on the display part of the biomagnetic field measuring apparatus of FIG. It is a figure which shows the system adjustment screen displayed on the display part of the biomagnetic field measuring apparatus of FIG.

Explanation of symbols

DESCRIPTION OF SYMBOLS 1 Magnetic shield room 2 Subject 3 Bed 4 Dewar 5 Automatic supply device 6 FLL circuit 7 Amplifier / filter / amplifier 8 Computer 8-1 Display unit 8-2 Keyboard 8-3 Mouse 20-1 to 20-8, 21- 1-21-8, 22-1 to 22-8, 23-1 to 23-8, 24-1 to 24-8, 25-1 to 25-8, 26-1 to 26-8, 27-1 27-8 Magnetic Sensor 10, 10 ', 10 ", 11, 11', 11" Coil 12, 12 ', 12 "SQUID
13, 14 Sensor 30 Chest 261 Scroll box 262 Scroll bar 271 Threshold cursor 273 to 275 Slider cursor 311, 312, 321, 331 to 334 Cursor 801 Title bar portion 802 Menu bar portion 803 Toolbar portion 804 Subject information portion 805 Analysis data part 806 Operation area part 808 Status bar part 807-1 Message bar part 807-2 Date and time display part 808 to 814 Icon

Claims (2)

A magnetic field measurement device display device that detects a magnetic field emitted from a living body of a subject by a plurality of magnetic sensors, and displays measurement data based on a detection result in an arbitrary display form,
Operation information comprising a processing function display unit for selecting an operation menu including a subject list, data measurement or data analysis, a subject information display unit representing information of the selected subject, and a data display region Display the display screen,
The data display area can be switched to a magnetic field diagram display screen divided into left and right,
The magnetic field diagram display screen is disposed on the left side and an analysis data display unit for displaying waveform diagrams measured by the plurality of magnetic sensors of the subject selected in the subject list unit, and on the right side. and an operation area display unit for processing operations of the waveform displayed on the analysis data display section Te,
The operation area display unit includes a heat flash as an operation menu for processing a waveform displayed on the analysis data display unit , and when the heat flash is selected, the measured waveform diagram is displayed on the analysis data display unit. A display device for a magnetic field measurement apparatus, wherein a heat flash operation screen for accepting selection of a magnetic sensor to be heat flashed among a plurality of magnetic sensors is newly displayed on the operation information display screen. In claim 1,
The heat flash operation screen is
A list of channels of the plurality of magnetic sensors for selection of a magnetic sensor to heat flash; and
Means for selecting a channel of the magnetic sensor to be heat flashed from the list of channels;
An execution key for performing a heat flash of the magnetic sensor of the selected channel ;
A display device for a magnetic field measurement apparatus, comprising: a cancel key for terminating display of the heat flash operation screen .

Images