JP2017064030A - Blood purification system and medical joint - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide a blood purification system in which a plurality of blood purifiers comprising a blood nozzle are connected in series with a medical joint and are used.SOLUTION: There is provided the blood purification system in which blood purifiers 200, 300 having supply/discharge ports of blood comprising Luer Lock connection mechanisms 202, 304, respectively are connected in series. The plurality of blood purifiers are configured in such a way that: the respective Luer Lock connection mechanisms are connected using a medical joint 400 into an almost integrated state; the medical joint has, in its inner surface, a flow channel 405 through which blood passes; the connection mechanisms are provided on both ends of the blood flow channel; one connection mechanism 401 provided in the medical joint is connected to the Luer Lock connection mechanism in one of the blood purifiers; and the other connection mechanism 402 provided in the medical joint, is connected to the Luer Lock connection mechanism in the other of the blood purifiers.SELECTED DRAWING: Figure 2

Description

  The present invention relates to a blood purification system and a medical joint.

  In artificial dialysis that is suitably used for patients with renal failure, the number of long-term dialysis patients with a dialysis calendar of 10 years or more is increasing due to advancement of dialysis equipment and technology, and complications peculiar to long-term dialysis patients are regarded as problems. Thus, a method for efficiently removing the etiological (related) substance of complications is disclosed.

  For example, in Patent Document 1, a blood purifier specialized in the ability to remove small molecular weight proteins represented by β2-microglobulin in blood is connected in series with a hemodialyzer that is one of the blood purifiers. A blood purification apparatus is disclosed, and the two blood purification devices are connected using a circuit.

  Patent Document 2 discloses a blood purification method in which a hemodialysis type, blood filtration type or hemodiafiltration type blood purification module and a blood perfusion type or blood adsorption type blood purification module are connected in series and used together. In the technique of using a plurality of blood purifiers in combination, it is described that it is preferable to use them connected in a line from the viewpoint of setting and removal efficiency of pathogenic substances in blood. However, in the connection between the two, the connection is made through a commonly used blood circuit, that is, a blood circuit having a flexible resin tube.

  However, since the blood purification module has a luer lock connection mechanism, when connecting a plurality of blood purification modules through the blood circuit, it will be connected while rotating the circuit, the circuit is twisted and difficult to use, At times, there have been problems in that the luer lock connection part is disengaged due to the restoring force of the twisted circuit, and the fluid in the circuit is drifted.

  As a means for solving the problem of twisting of these circuits, for example, Patent Document 3 discloses that a torsion of a fluid guide tube at the time of tightening can be avoided, and a male luer is applied even when a load is applied to the housing when the housing is unexpectedly loosened. As a female connector that does not easily disengage with the female luer, the female connector comprises a core member, a housing mounted on the outer periphery of the core member, and a stopper fixed at a predetermined position away from the core member, A female connector is disclosed in which the distance (L1) between the flange and the stopper is equal to or greater than the total length (L2) of the cylindrical portion of the housing.

JP-A-9-266948 JP 2006-305306 A JP 2005-192882 A

  When a plurality of blood purifiers are used in combination, the volume of blood taken out of the body is generally increased, and there is a concern about a decrease in blood pressure. Therefore, it is required to minimize the blood volume. The problem concerning any of-3 and the solution method are not described.

  Since blood circuits with flexible resin tubes are used to connect between blood purifiers, for example, hemodialyzers and other blood purifiers, the blood purifier and hemodialyzer are each dedicated when setting. Next, it is necessary to connect the two via the blood circuit. For this reason, two dedicated clamping devices, which had been sufficient in the past, are required, setting takes time, and complicated work such as considering the piping space of the blood circuit connecting the two is necessary. Met.

  In addition, it is necessary to perform a work called priming that replaces air or filling liquid in the blood purifier with physiological saline before dialysis treatment. In this priming work, the blood purifier is moved up and down to promote the replacement. May be reversed. The reversing operation requires that each blood purifier is first removed from the dedicated clamping device, then reversing, reattaching and working with both hands is very poor, and workability is very poor, and when multiple blood purifiers are connected. It was difficult to work alone.

  Moreover, even if the twisting of the tube circuit at the time of luer lock connection can be avoided by the technique according to the above-mentioned Patent Document 3, the twisting of the circuit between the plurality of blood purifiers generated during the operation of the priming or the like, It has been difficult to prevent fluid drift due to twisting and meandering of circuits between blood purifiers.

  An object of the present invention is to enable minimization of the volume of blood taken outside the body in a blood purification system in which a plurality of blood purifiers having blood supply / discharge ports provided with a luer lock connection mechanism are connected in series. It is another object of the present invention to provide a blood purification system capable of simplifying a connecting operation and a priming operation of a plurality of blood purifiers, and a medical joint used therefor.

In order to solve the above-mentioned problem, the present invention is a blood purification system in which a plurality of blood purifiers having a blood sharing / drainage port provided with a luer lock connection mechanism are connected in series,
The plurality of blood purifiers, the luer lock connection mechanism of each of the blood purifiers are connected to each other substantially integrally by a medical joint,
The medical joint has a flow path through which blood passes on the inner surface, and connection mechanisms are provided at both ends of the blood flow path,
One of the connection mechanisms provided in the medical joint is connected to a luer lock connection mechanism in one of the blood purifiers,
The other of the connection mechanisms provided in the medical joint provides a blood purification system connected to a luer lock connection mechanism in another blood purifier.

In addition, as a joint preferably used in the blood purification system, a medical joint having a flow path through which blood passes on the inner surface and provided with connection mechanisms at both ends of the blood flow path,
At least a part of the inner surface provided with the blood flow path is a Luer tapered surface whose diameter increases toward the tip,
Provided is a medical joint in which a male screw is provided on at least a part of an outer peripheral surface corresponding to the luer tapered surface.

  By using the blood purification system of the present invention, and preferably the medical joint of the present invention, the volume of blood taken out of the body can be minimized. In addition, since a circuit using a tube or the like is not required, setting can be simplified and the piping space of the blood circuit can be reduced.

  In the present invention, the plurality of blood purifiers are connected to the luer lock connecting mechanism provided in each blood nozzle substantially integrally via the medical joint, so that not only the setting but also the priming workability thereafter is improved. This is also advantageous in terms of improvement.

BRIEF DESCRIPTION OF THE DRAWINGS It is a schematic block diagram of the medical coupling which concerns on one Embodiment of this invention, and the blood purification system using the same, (A) is the state before the connection of the several blood purifier by a medical coupling, (B) is after a connection. Each state is shown. In the blood purification system shown in FIG. 1, (A) is a schematic block diagram which shows another aspect of the medical coupling which concerns on this invention, (A) is the state before the connection of the some blood purifier by a medical coupling, (B) is Each state after connection is shown. In the blood purification system shown in FIG. 1, it is the schematic which shows the locking mechanism with which the medical joint which concerns on this invention was equipped, (A) is the state before the connection of the several blood purifier by a medical joint, (B ) Shows the state after connection. FIG. 4 is a schematic view showing another aspect of the lock mechanism provided in the medical joint in the blood purification system according to the present invention similar to FIG. 3, and (A) is a state before a plurality of blood purifiers are connected by the medical joint. The state, (B) shows the state after connection. In the blood purification system according to the present invention similar to FIG. 3, it is a schematic view showing still another aspect of the lock mechanism provided in the medical joint, and (A) is a connection of a plurality of blood purifiers by the medical joint. The previous state, (B) shows the state after connection. In the blood purification system according to the present invention similar to FIG. 3, a schematic view showing still another aspect of the lock mechanism provided in the medical joint, (A) is before connection of a plurality of blood purifiers by the medical joint. (B) shows the state after connection. The schematic structure figure of the conventional blood purification system is shown.

  The blood purification in the present invention refers to the purpose of removing a target pathogenic substance from blood by filtration, diffusion, adsorption or the like using the characteristics of a purification function body.

  Moreover, it is preferable that the plurality of blood purifiers used in the blood purification system of the present invention are different from each other mainly in the substances to be removed from the blood. When the substances to be removed are different, for example, even when a plurality of blood purifiers removes the substance A in common, only one blood purifier removes another substance B, or Even if the substances A and B are removed in common, there is a case where there is a significant difference between the removal rate of the substance A and the removal rate of the substance B. That is, it is possible to connect blood purifiers containing a plurality of materials (purification function bodies) having different properties in a row and perform different “blood purification” according to the characteristics of the respective purifiers. The purpose is to use the system. Specifically, the materials, forms, etc. of the materials accommodated in the purifier are often different. For example, a combination of a hemodialyzer, which is one of the blood purifiers, and a β2 microglobulin adsorption column, an endotoxin adsorption column, a cytokine adsorption column, a leukocyte removal column, and the like can be mentioned, but the invention is not particularly limited thereto.

  In the present invention, the supply and discharge ports of the blood purifier are provided with a luer lock connection mechanism for external piping connection, and a plurality of blood purifiers are connected in series via a medical joint. A luer lock is a simple, inexpensive, and reliable connection mechanism. A male luer with a spiral groove of a predetermined shape on either the external piping or the port side connection part, and a spiral protrusion that fits in the groove on the other side. A female luer provided with a liquid-tight connection is achieved by rotating one of them in a state where they are abutted against each other.

  The “joint” in the above is a structure that joins two parts, mainly two parts. For example, the two joints are connected via a tube made of a soft material such as vinyl chloride, polyurethane, or polybutadiene. This does not apply to the structure that joins. In the present invention, a plurality of blood purifiers are connected by such a joint. Specifically, the medical joint according to the present invention has a flow path (hereinafter referred to as a blood flow path) through which blood passes on the inner surface, and is connected to a luer lock connection mechanism at each of both ends of the blood flow path. A mechanism is provided, one of which is connected to a luer lock connection mechanism in one blood purifier, and the other is connected to a luer lock connection mechanism in another blood purifier, thereby providing a plurality of blood A purifier is connected.

  In addition to the blood purifier, the term “medical” refers to being used in the medical field such as a body fluid treatment device, a syringe, and a blood circuit.

  The effect of the present invention can be obtained even if at least one of the plurality of blood purifiers is connected by the connection method of the present invention. However, from the viewpoint of workability and blood volume, all blood purifiers are It is more preferable to connect by a connection method.

  FIG. 7 shows a conventional blood purification system. As described above, in the conventional blood purification system, when a plurality of blood purification devices are connected in a row, the blood purification devices are connected to each other via a blood circuit having a flexible resin tube.

  Meanwhile, embodiments of the present invention will be described below with reference to the drawings.

  FIG. 2 shows a blood purification system according to an embodiment of the present invention, but the following preferred modes and examples are not limited to this case. In FIG. 2, the blood purifier 200 and the second blood purifier 300 are provided with blood supply ports and discharge ports communicating with the inside of the blood purifier at both longitudinal ends of the blood purifier. Each of the discharge ports is equipped with a male luer.

  The medical joint 400 has a first luer taper surface 406 and a second luer taper surface 407 whose diameter increases toward the distal end in a blood channel 405 that is an inner surface of the medical joint 400. For example, a 6/100 taper is used as the luer taper. The entire surface of blood channel 405 need not be a Luer tapered surface, and may be at least a part of the inner surface provided with the blood channel. For example, it may be provided only near both ends. In addition, although it has the said lure taper surface, the blood flow path 405 has a substantially linear shape. A first male screw 403 and a second male screw 404 are provided on at least a part of the outer peripheral surface corresponding to the inner surface provided with the luer tapered surfaces 406 and 407, respectively. The joint end portion including the first luer taper surface 406 and the first male screw 403 is one of the connection mechanisms in the joint, and here is a first female luer 401. A portion including the second luer taper surface 407 and the second male screw 404 is the other of the connection mechanisms in the joint, and is a second female luer 402 here. The first female luer 401 is inserted into the space between the inner nozzle 205 and the outer nozzle 206, and the second female luer 402 is inserted into the space between the inner nozzle 305 and the outer nozzle 206. In addition, a flange 408 having a flange portion protruding in a direction perpendicular to the direction of the blood flow path is provided at the central portion of the outer peripheral surface of the medical joint in the direction of the blood flow path. Is provided. The shape and material of the medical joint 400 are not particularly limited, and even if the first luer 401, the second luer 402, and the flange 408 are molded as a single body, they are individually molded and ultrasonic waves are formed. They may be integrated by welding or the like. As the material, a resin is preferable from the viewpoint of productivity and disposable properties. Specifically, polypropylene, polycarbonate, polystyrene, polyvinyl chloride, and the like are preferably used in terms of moldability, strength, chemical resistance, and the like. .

  In this embodiment, a non-luer taper surface is provided between the first luer taper surface 406 and the second luer taper surface 407 in the blood flow path 405. In consideration of factors such as the shape of the male luer, the first luer tapered surface 406 and the second luer tapered surface 407 may be directly connected without providing the non-luer tapered surface.

  Moreover, as the shape of the flange 408, a cylindrical shape, an elliptical cylindrical shape, a rectangular cylindrical shape, or the like is used, and is appropriately selected from the viewpoints of formability, strength, operability, and the like.

  In addition, when the repellent 409 is provided on the outer surface of the flange 408, when the blood purifier and the medical joint 400 are connected by luer lock, the male luer tip surface of the blood purifier is pressed against the repellent 409. The repulsive force generated between the purifier and the medical joint 400 increases, and the increased repulsive force can prevent loosening of the luer lock connection.

  In order to achieve the above object, when the thickness of the repelling body 409 is smaller than 0.1 mm, the deformation allowance is small, so the repulsive force is small, and when it is larger than 5 mm, the deformation becomes large and the rigidity when connected is lowered. Therefore, 0.1 mm or more is preferable, 0.2 mm or more is more preferable, while 5 mm or less is preferable and 1 mm or less is more preferable. The material of the rebound material 409 is not particularly limited, but rubber, thermoplastic elastomer, and soft resin are preferably selected.

  Then, the female screw 207 provided on the inner surface of the inner nozzle 206 in the male luer 202 of the blood purifier 200 and the first male screw 403 provided on the outer peripheral surface of the first female luer 401 of the medical joint 400 are screwed together. Then, the female screw 307 provided on the inner surface of the inner nozzle 306 in the male luer 304 of the second blood purifier 300 and the second male screw 404 provided on the outer peripheral surface of the second female luer 402 of the medical joint 400 are screwed. The plurality of blood purifiers are substantially fixedly connected by pressing the front end surface of the outer nozzle 206 of the blood purifier 200 and the front end surface of the outer nozzle 306 of the second blood purifier 300 against the repelling body 409. It is also possible to prevent the subsequent loosening.

  Moreover, if the luer lock mechanism of the connection part of the medical joint 400 is made to conform to ISO594-2 (issued in 1998), it can be connected to a blood purifier regardless of manufacturer or product.

  Here, in FIG. 1, the blood purifier 200 is disposed downstream of the blood purification system 100 based on the blood flow method, but may be disposed upstream of the present system.

  As described above, the male luer 202 of the blood purifier 200 and the first female luer 401 of the medical joint 400, the male luer 304 of the second blood purifier 300, and the second female luer 402 of the medical joint 400 are respectively lures. By locking and connecting the distal end surface of the outer nozzle 206 of the blood purifier 200 and the distal end surface of the outer nozzle 306 of the second blood purifier 300 against the flange 408 or the repellent body 409 of the medical joint 400, a plurality of However, for the purpose of reducing the load generated at the luer lock connecting portion, improving the rigidity of the connecting portion, and preventing the loosening of the connecting portion, for example, FIG. As shown in FIG. 6, the flange 408 of the medical joint 400 has a portion extending from the heel portion in the direction of the blood flow path or a luer outer peripheral surface of the blood purifier or a supply. · To lock the discharge port and the medical joint, so to speak, may be to form a "lock mechanism" 410. Further, the lock mechanism 410 may be extended in both directions along the blood flow path with reference to the flange 408, or may be extended in only one direction. In the case of extending in both directions, the shape of the blood purifier is In addition, the shape of the lock mechanism can be designed in the first direction and the second direction.

  In the case of the embodiment shown in FIG. 3, the locking mechanism 410, which is a portion extending from the flange 408, causes the male luer 202 of the blood purifier 200 and the first female luer 401 of the medical joint 400 to be connected by a luer lock. In this case, the outer peripheral surface of the outer nozzle 206 of the blood purifier 200 and the inner peripheral surface of the lock mechanism 410 are fitted together, and the lock mechanism 410 can grip the outer periphery of the outer nozzle 206. The blood purifier 200 and the medical joint 400 can be substantially fixed in a state where the load generated in the part is reduced. The connection between the second blood purifier 300 and the medical joint 400 is the same as described above, and it is possible to reduce the risk of damage to the luer lock connection portion against reversal work during priming and impact during use. It is.

  In the case where the flange 408 and the lock mechanism 410 shown in this embodiment are integrated, they may be formed as a single piece, or the flange 408 and the lock mechanism 410 may be formed separately and post-processed such as ultrasonic welding. Can also be integrated.

  FIG. 4 illustrates a blood purification system according to a mode different from FIG. A different part is a part related to the above-mentioned lock mechanism. In the lock mechanism of this aspect, when the blood purifier 200 and the medical joint 400 are connected by a luer lock, the outer peripheral portion of the outer nozzle 206 of the blood purifier 200 is connected. The so-called snap-fit structure in which the first protrusion 411 provided on the inner peripheral surface of the lock mechanism 410 of the medical joint 400 is fitted in the provided recess 208 has a so-called snap fit structure. Looseness after connection can also be prevented.

  The concave portion 208 may be provided on the entire outer peripheral surface of the outer nozzle or may be provided partially in the circumferential direction, and the concave portion 208 may be provided in a plurality of stages in the longitudinal direction of the outer peripheral surface of the outer nozzle. The first protrusions 411 may be provided on the entire circumference of the lock mechanism 410 or partially in the circumferential direction. However, a plurality of the first protrusions 411 may be partially arranged in the circumferential direction in terms of formability and operability. preferable. In this embodiment, the blood purifier is provided with a recess and the medical joint is provided with a protrusion, but conversely, the blood purifier may be provided with a protrusion and the medical joint is provided with a recess. Moreover, in this aspect, although the protrusion part and the recessed part are provided in the circumferential direction with respect to the longitudinal direction (blood flow path direction) of the blood purifier and the medical joint, the longitudinal direction end part of each of the blood purifier and the medical joint Protrusions and recesses may be provided on the surface.

  FIG. 5 illustrates a blood purification system according to a mode different from FIG. After the blood purifier 200 and the medical joint 400 are connected by a luer lock, the first nut 415 disposed on the outer peripheral surface of the lock mechanism 410 of the medical joint 400 is screwed using the lock mechanism first male screw 413. By fixing, the lock mechanism 410 can grip the outer periphery of the outer nozzle 206 more firmly than the embodiment shown in FIG. 3, and the deformation of the lock mechanism 410 when an external force is applied can be suppressed. The blood purifier 200 and the medical joint 400 can be connected more rigidly.

  In addition, although the shape and material of the 1st nut 415 are not specifically limited, Resin is preferable from a disposable viewpoint like a medical coupling. Moreover, although the screwing fixing mechanism using a nut is illustrated in the present embodiment, any mechanism that is provided on the outer peripheral portion of the locking mechanism 410 and can be slid and fixed in the axial direction of the medical joint 400 may be used. Specific examples include a press-fitting mechanism and a snap-fit mechanism that use fitting of members, a spring mechanism that uses a restoring force of a spring, and the like.

  FIG. 6 illustrates a blood purification system according to a mode different from FIG. After the blood purifier 200 and the medical joint 400 are connected by a luer lock, the first slide portion 419 provided on the lock mechanism 410 of the medical joint 400 is blood purified using the first slide mechanism 417 provided separately. The repellent force is generated between the slide part 415 and the blood purifier 200 by sliding in the direction of the purifier 200, contacting with the blood purifier 200, and pressing, and the blood purifier 200 and the medical device are utilized by utilizing this repulsive force. The joint 400 is fixed.

  The shape, material, and mechanism of the first slide part 419 are not particularly limited. For example, regarding the shape, the cross-sectional shape of the first slide part 419 in the direction perpendicular to the longitudinal direction is that of the blood purifier 200. Since the port 201 is mainly circular, the first slide portion 419 is also preferably circular from the viewpoint of operability. Further, the first slide portion 419 is pressed against the blood purifier 200 to generate a repulsive force on the contact surface. However, if it is circular, a force acts uniformly in all directions, and stability when fixed is good. Tend to be. Therefore, the cross-sectional shape is preferably a circular shape.

  The material of the first slide part 419 is not particularly limited, as is the case with the material of the medical joint body. However, the formability, strength, and ease of visual recognition of the luer lock connection part and the port part in the slide mechanism, etc. From the point of view, a transparent resin is preferable. Specific examples include polycarbonate, polystyrene, polyvinyl chloride, and polypropylene.

  In the case of the embodiment shown in FIG. 6, the shape of the contact surface of the blood purifier 200 with the first slide portion 419 is an arbitrary shape, and therefore, the end surface on the outer side in the longitudinal direction of the first slide portion 419 (with the blood purifier 200). By providing the first cushion material 421 on the contact surface side), the curved surface followability is improved, the contact area with the blood purifier 200 is increased, and a more stable fixed state is obtained. When the thickness of the first cushion material 421 is smaller than 0.5 mm, the deformation margin is small, and when the thickness is larger than 10 mm, the deformation of the cushion material becomes large, and the rigidity when pressed and fixed is lowered. The above is preferable, and 1 mm or more is more preferable, while 10 mm or less is preferable and 5 mm or less is more preferable. The material of the first cushion material 421 is not particularly limited, but rubber, thermoplastic elastomer, or flexible resin is preferably selected.

  The first slide mechanism 417 provided in the first slide part 419 is slidable in the longitudinal direction of the blood purifier 200, and generates a repulsive force between the first slide part 419 and its contact surface when pressed and fixed. Any mechanism can be used and can be designed arbitrarily. Specific examples of the first slide mechanism 417 include, for example, a screw type using the rotation of a screw or a spring type using a restoring force of a spring.

  As illustrated above, the lock mechanism 410 prevents the load of the luer lock connection portion from being reduced, the rigidity is improved, and the luer lock connection is not loosened when a plurality of blood purifiers are connected via a medical joint. The shape, material, and mechanism are not particularly limited as long as the purpose of serving as a guide is achieved.

  When a plurality of blood purifiers are used in combination via the medical joint 400 of the present invention, a blood circuit (tube 601 in FIG. 7) having a flexible resin tube for connecting the blood purifiers to each other is unnecessary and substantially fixed. Therefore, by reducing the blood volume for the blood circuit, it is possible to minimize the volume of blood taken out of the body, thereby contributing to the reduction of the treatment load on the patient. In addition, since the setting and handling required at the time of treatment can be performed easily and reliably, the system is suitable for purifying the blood of patients with renal failure.

100 Blood Purification System 200 Blood Purifier 201 Supply Port 202 Male Luer 203 Discharge Port 204 Male Luer 205 Inner Nozzle 206 Outer Nozzle 207 Female Screw 208 Recess 300 Second Blood Purifier 301 Supply Port 302 Male Luer 303 Discharge Port 304 Male Luer 305 Inner nozzle 306 Outer nozzle 307 Female screw 308 Recess 400 Medical joint 401 First female luer 402 Second female luer 403 First male screw 404 Second male screw 405 Blood channel 406 First luer tapered surface 407 Second luer tapered surface 408 Flange 409 Rebound body 410 Lock mechanism 411 First protrusion 412 Second protrusion 413 Lock mechanism first male screw 414 Lock mechanism second male screw 415 First nut 416 Second nut 417 First slide mechanism 418 2 slide mechanism 419 first slide portion 420 second sliding portion 421 first blood circuit 601 tube 602 female luer 603 female luer having a cushioning material 422 second cushion member 500 conventional blood purification system 600 flexible resin tube

Claims (7)

A blood purifier having a blood supply / discharge port provided with a luer lock connection mechanism is a blood purification system in which a plurality of blood purifiers are connected in series,
The plurality of blood purifiers, the luer lock connection mechanism of each of the blood purifiers are connected to each other substantially integrally by a medical joint,
The medical joint has a flow path through which blood passes on the inner surface, and connection mechanisms are provided at both ends of the blood flow path,
One of the connection mechanisms provided in the medical joint is connected to a luer lock connection mechanism in one of the blood purifiers,
The blood purification system, wherein the other of the connection mechanisms provided in the medical joint is connected to a luer lock connection mechanism in another blood purifier.   The blood purification system according to claim 1, wherein at least one of the blood purification devices is a hemodialyzer.   3. The medical joint according to claim 1, wherein the blood channel has a substantially linear shape, and a flange having a flange protruding in a direction perpendicular to the direction of the blood channel is provided on an outer peripheral surface. Blood purification system.   The flange is provided with a portion extending from the heel portion in the direction of the blood flow path, and the extending portion and the luer outer peripheral surface or supply / discharge port of the blood purifier are fixed by the extending portion. The blood purification system according to any one of claims 1 to 3. A medical joint having a flow path through which blood passes on the inner surface and provided with a connection mechanism at each of both ends of the blood flow path,
At least a part of the inner surface provided with the blood flow path is a Luer tapered surface whose diameter increases toward the tip,
A medical joint in which a male screw is provided on at least a part of an outer peripheral surface corresponding to the luer tapered surface.   The medical joint according to claim 5, wherein the blood channel has a substantially linear shape, and a flange having a flange protruding in a direction perpendicular to the direction of the blood channel is provided on the outer peripheral surface. The medical joint according to claim 6, wherein the flange is provided with a portion extending from the heel portion in the blood flow path direction.

Images