JP2008220779A - Dental oct apparatus - Google Patents

Dental oct apparatus Download PDF

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JP2008220779A
JP2008220779A JP2007065740A JP2007065740A JP2008220779A JP 2008220779 A JP2008220779 A JP 2008220779A JP 2007065740 A JP2007065740 A JP 2007065740A JP 2007065740 A JP2007065740 A JP 2007065740A JP 2008220779 A JP2008220779 A JP 2008220779A
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tissue
light
reference light
optical path
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JP5071629B2 (en
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Shohei Kamaguchi
昌平 釜口
Yukinori Mitsuhata
幸則 三畑
Kazunobu Ogawa
和伸 小川
Yoshikazu Kurose
善和 黒瀬
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Morita Tokyo Manufacturing Corp
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Abstract

<P>PROBLEM TO BE SOLVED: To solve problems that a dental OCT (optical coherence tomography) measures both of hard tooth and soft periodontal tissues in the narrow and complicated oral cavity, directivities of top/bottom/left/right of tomographic images to be displayed are different according the postures of an operator and a patient and measured sites, the measurement range is narrow, and in some cases, it is often difficult to determine which position in the oral cavity a tomographic image shows. <P>SOLUTION: This dental OCT apparatus processes the tomographic image of a subject acquired by the OCT measured by an optical interference between a signal light reflected at a deep layer position from the surface inside the oral cavity of the subject and a reference light reflected at a path edge of the reference light, displays the respective tissues of the subject with different colors respectively and changes their gradations according to the attenuation of the detection signal. <P>COPYRIGHT: (C)2008,JPO&INPIT

Description

本件は、歯科用OCT装置の取得断層画像に係り、特に被検査体の各組織を、それぞれ異なった色彩でかつ、検出信号の減衰に対応した連続階調で表示する断層画像の表示装置に関する。   The present invention relates to an acquired tomographic image of a dental OCT apparatus, and more particularly to a tomographic image display apparatus that displays each tissue of an object to be inspected with different colors and continuous gradation corresponding to attenuation of a detection signal.

従来、医療用の光断層画像として、例えば眼科、皮膚科等の生体におけるOCT断層画像が実用に供されているが、被検査体が軟組織でありまた、計測は開放された広い部分から行うことができるため計測器の形状は大きくてもよくかつ、測定も一定方向であるため断層画像の取得及びその判読は比較的容易であり、また画像も白黒でもよかった。   Conventionally, as an optical tomographic image for medical use, for example, an OCT tomographic image in a living body such as an ophthalmologist or a dermatologist is practically used. However, an object to be inspected is a soft tissue, and measurement is performed from a wide open part. Therefore, the shape of the measuring device may be large, and since the measurement is in a certain direction, it is relatively easy to acquire and interpret the tomographic image, and the image may be black and white.

しかしながら、歯科用OCT装置における口腔内被検査体の歯においては、表面が硬組織のエナメル質であり、その中側は硬組織の象牙質であり、同象牙質の下方の外側は軟組織の歯肉で覆われていて、硬、軟両組織に区分される。
また、口腔内は狭小で複雑であり、その計測は、施術者、患者の姿勢と、計測の部位によって上下左右の方向性が異なり、さらに計測の範囲が狭いため、断層画像がどの位置に該当しているのか判読が困難な場合があった。
そして、特に硬組織から得られる信号は極小であり、その表示手段は高度の技術を要するが、診断時には各組織及びその境界線や組織内の検出信号の減衰状態が、色彩表示により一見して判別でき、かつ方向性も判別できる断層画像であることが望ましい。
However, in the teeth of the oral examination object in the dental OCT apparatus, the surface is hard tissue enamel, the inner side is hard tissue dentin, and the lower outer side of the dentin is soft tissue gingiva. It is covered with hard and soft tissues.
In addition, the oral cavity is narrow and complicated, and the measurement differs depending on the posture of the operator and patient and the direction of measurement, and the direction of the measurement is narrow. Sometimes it was difficult to interpret.
In particular, the signal obtained from the hard tissue is minimal, and its display means requires a high level of technology, but at the time of diagnosis, the attenuation state of each tissue and its boundary line and the detection signal in the tissue can be seen at a glance by color display. It is desirable that the tomographic image can be discriminated and the directionality can be discriminated.

上記に鑑み、本発明者等は鋭意実験研究の結果次の手段により上記課題を解決した。
(1)低コヒーレンス光源からの光を、信号光と参照光とに分離して、それぞれ信号光路及び参照光路に導くようにし、前記信号光路には、前記信号光を口腔内被検査体の表面に照射し、照射点を前記被検査体表面に沿って走査する照射点走査手段が設けられ、
また、前記参照光路には,参照光路の路端で参照光を反射させる光学素子を有し、参照光の光路長を走査する参照光路長走査手段が設けられ、前記参照光の光路長を走査して、参照光の光路長に対応する前記口腔内被検査体表面からの深層位置で反射した信号光と、前記参照光の路端で反射した参照光との光干渉に基づいて、口腔内被検査体の断層を計測する歯科用OCT装置において、口腔内被検査体の硬組織又は軟組織あるいは、硬組織及び軟組織の各組織の断層画像を、それぞれ異なった色彩でかつ、検出信号の減衰に対応した連続階調で表わす表示装置を備えてなることを特徴とする歯科用OCT装置。
(2)口腔内被検査体が、歯牙組織又は歯周組織あるいは、歯牙組織及び歯周組織であることを特徴とする前項(1)に記載の歯科用OCT装置。
In view of the above, the present inventors have solved the above problems by the following means as a result of intensive experimental research.
(1) The light from the low-coherence light source is separated into signal light and reference light, which are guided to the signal light path and the reference light path, respectively, and the signal light is on the surface of the intraoral inspected object in the signal light path. Irradiation point scanning means is provided for scanning the irradiation point along the surface of the object to be inspected.
The reference optical path includes an optical element that reflects the reference light at a path end of the reference optical path, and is provided with a reference optical path length scanning unit that scans the optical path length of the reference light, and scans the optical path length of the reference light. Then, based on the optical interference between the signal light reflected at the deep layer position from the surface of the intraoral inspected object corresponding to the optical path length of the reference light and the reference light reflected at the end of the reference light, In a dental OCT device that measures the tomography of the object to be inspected, the tomographic image of the hard tissue or soft tissue of the intraoral inspected object or each tissue of the hard tissue and soft tissue has a different color and attenuates the detection signal. A dental OCT apparatus comprising a display device represented by corresponding continuous gradation.
(2) The dental OCT apparatus according to (1) above, wherein the intraoral subject is a tooth tissue, periodontal tissue, or tooth tissue and periodontal tissue.

本発明によれば、
口腔内被検査体表面からの深層位置で反射した信号光と、参照光の路端で反射した参照光との光干渉に基づいて、被検査体の断層を計測する歯科用OCT装置において、
被検査体の断層画像を、被検体の、硬組織又は軟組織あるいは、硬組織及び軟組織の各組織をそれぞれ異なった色彩でかつ、検出信号の減衰に対応した連続階調で表示するようにしたため、
従来、歯科用OCT装置においては、狭小で複雑な口腔内での操作と、施術者、患者の位置や姿勢と、計測の部位によって異なる上下左右の方向性と、かつ狭い計測範囲により、断層画像がどの位置に該当しているのか判読が困難な場合があったが、
口腔内の例えば、歯のエナメル質及び象牙質等の硬組織と、歯肉等の軟組織とが色彩によって境界区分され、かつ、検出信号の減衰に対応した連続階調で表示することによって一見して各組織の状態が判りかつ、色別によって上下左右の方向性も判別できる断層画像を取得することができる。
According to the present invention,
In a dental OCT apparatus that measures a tomogram of an object to be inspected based on optical interference between signal light reflected at a deep layer position from the surface of an intraoral object to be inspected and reference light reflected at a road edge of the reference light,
Because the tomographic image of the test object is displayed in a continuous tone corresponding to the attenuation of the detection signal, the hard tissue or soft tissue or the hard tissue and soft tissue of the subject are displayed in different colors, respectively.
Conventionally, in a dental OCT apparatus, a tomographic image is obtained by a narrow and complicated operation in the oral cavity, the position and posture of a practitioner and a patient, vertical and horizontal directions that vary depending on the measurement site, and a narrow measurement range. In some cases, it was difficult to interpret the position of
At first glance, hard tissues such as tooth enamel and dentin in the oral cavity and soft tissues such as gingiva are separated by color and displayed in a continuous tone corresponding to the attenuation of the detection signal. It is possible to obtain a tomographic image in which the state of each tissue is known and the direction of the upper, lower, left, and right directions can be determined by color.

発明を実施するための最良の形態を図面に基づいて以下に説明する。
図1は、歯科用OCT装置の構成説明のブロック図である。
図において、1は診断用プローブ、2は参照光路長走査手段、5は光学素子、6は参照光、7はコリメートレンズ、8は深さ方向走査、9は低コヒーレンス光源、10は光ファイバ、11は検出信号線、12は光ファイバカプラ、13は光検出器、14は制御信号線、15は信号処理部、16はコンピュータ、17は表示部、18は断層画像、19は横又は縦方向走査、20は信号光、21は被検査体、22は歯、23は歯肉、24はエナメル質、25は象牙質、26は歯髄、27は歯槽骨を示す。
The best mode for carrying out the invention will be described below with reference to the drawings.
FIG. 1 is a block diagram illustrating the configuration of a dental OCT apparatus.
In the figure, 1 is a diagnostic probe, 2 is a reference optical path length scanning means, 5 is an optical element, 6 is reference light, 7 is a collimating lens, 8 is a depth direction scan, 9 is a low coherence light source, 10 is an optical fiber, 11 is a detection signal line, 12 is an optical fiber coupler, 13 is a photodetector, 14 is a control signal line, 15 is a signal processing unit, 16 is a computer, 17 is a display unit, 18 is a tomographic image, 19 is horizontal or vertical direction Scanning, 20 is signal light, 21 is a test object, 22 is a tooth, 23 is gingiva, 24 is enamel, 25 is dentin, 26 is pulp, and 27 is alveolar bone.

低コヒーレンス光源9からの光は、光ファイバ10から光ファイバカプラ12で被検査体21への信号光20と、参照光6とに分割され、前記参照光6は参照光路長走査手段2において光学素子5で反射回帰して、被検査体21から回帰する信号光20と共に、前記光ファイバカプラ12で合成された干渉光を光検出器13で検出し、その出力は検出信号線11から信号処理部15を経由してコンピュータ16に入力され、表示器17には断層画像18が色別表示される。同断層画像18は、歯肉23、エナメル質24、象牙質25、歯髄26及び歯槽骨27の各組織で構成された断層像を表示している。   The light from the low-coherence light source 9 is split into the signal light 20 to the device under test 21 and the reference light 6 by the optical fiber coupler 12 from the optical fiber 10, and the reference light 6 is optically transmitted by the reference optical path length scanning means 2. The interference light synthesized by the optical fiber coupler 12 is detected by the optical detector 13 together with the signal light 20 which is reflected and returned from the element 5 and returns from the object to be inspected 21, and its output is signal processed from the detection signal line 11. The image is input to the computer 16 via the unit 15, and the tomographic image 18 is displayed by color on the display unit 17. The tomographic image 18 displays a tomographic image composed of tissues of the gingiva 23, enamel 24, dentin 25, dental pulp 26, and alveolar bone 27.

図2は、図1において被検査体の歯を縦方向に走査し、その時の1点を、深さ方向に連続走査したときに取得される各深度における信号強度のグラフで、縦軸は信号強度(dB)、横軸は深さ方向の距離(mm)を示す。
事例は健常者の生体歯牙である。
上記グラフは、最初の信号強度が最大の、エナメル質24の表面を示し、続いて深さ方向の距離が大きくなるに連れて信号強度は、エナメル質の減衰部24’のように順次減衰してゆき、次の信号強度が急に大きくなる象牙質25の表面に至る。
前記象牙質25以降は深さ方向に象牙質が続き信号強度は象牙質の減衰部25’のように順次減衰してゆく。
そして、断層の原画像(図3)は、前記縦軸の1点を、所定距離縦方向に連続して走査することによって取得される。
FIG. 2 is a graph of signal intensity at each depth acquired when the teeth of the object to be inspected in FIG. 1 are scanned in the vertical direction and one point at that time is continuously scanned in the depth direction. Strength (dB), the horizontal axis indicates the distance (mm) in the depth direction.
The case is a healthy person's living teeth.
The above graph shows the surface of the enamel 24 where the initial signal intensity is maximum, and the signal intensity gradually attenuates as the distance in the depth direction increases like the enamel attenuation part 24 '. It reaches the surface of the dentin 25 where the next signal intensity suddenly increases.
After the dentin 25, the dentin continues in the depth direction, and the signal intensity gradually attenuates like the dentin attenuation part 25 '.
The original image of the tomogram (FIG. 3) is acquired by continuously scanning one point on the vertical axis in the vertical direction for a predetermined distance.

図3は、歯のエナメル質と象牙質の断層画像の原画像で、
縦軸は縦方向の距離(mm)、横軸は深さ方向の距離(mm)を示す。図において28は空間である。
原画像は白黒画像である。そして前記エナメル質24の表面及び象牙質25の表面及び空間28と、前記エナメル質の減衰部24’、象牙質の減衰部25’の深さに対する信号強度が連続階調で示されている。
そして、前記原画像に対し、以下に示すように各種の画像処理を行う。
Figure 3 shows the original image of the tomographic image of the tooth enamel and dentin.
The vertical axis indicates the distance (mm) in the vertical direction, and the horizontal axis indicates the distance (mm) in the depth direction. In the figure, 28 is a space.
The original image is a black and white image. The signal strength with respect to the depth of the surface of the enamel 24, the surface of the dentin 25 and the space 28, and the depths of the enamel attenuation portion 24 ′ and the dentin attenuation portion 25 ′ is shown in continuous tone.
Then, various kinds of image processing are performed on the original image as described below.

図4は、深さ方向の距離による光の減衰の補正図で、処理を容易にするため一旦前記減衰を補正している。
図において、縦方向の距離(mm)、横軸は深さ方向の距離(mm)を示す。
図5は、図4のノイズ成分を除去した図である。前記ノイズ成分の除去は例えばフーリエ変換とハニング関数処理等により行う。
図の縦軸、横軸は図4と同様である。
FIG. 4 is a correction diagram of light attenuation depending on the distance in the depth direction, and the attenuation is corrected once for easy processing.
In the figure, the distance in the vertical direction (mm), and the horizontal axis indicates the distance in the depth direction (mm).
FIG. 5 is a diagram in which the noise component of FIG. 4 is removed. The noise component is removed by, for example, Fourier transform and Hanning function processing.
The vertical and horizontal axes in the figure are the same as in FIG.

図6は、エナメル質、象牙質各領域の任意配色による色づけと、メディアン処理による境界部分の細部凹凸の除去図、である。
この段階は、各組織とその境界を強調するための画像処理である。
そして、前記図3のエナメル質の減衰部24’の部分は、色相緑に色付けし、
象牙質の減衰部25’の部分は色相青に色づけして、区分を明確にしている。
図7は、図6の境界の平均化処理図で、さらに境界を均して見やすくしている。
FIG. 6 is a diagram illustrating coloring of enamel and dentin by an arbitrary color scheme and removal of detailed irregularities in a boundary portion by median processing.
This stage is image processing for emphasizing each tissue and its boundary.
Then, the portion of the enamel attenuation portion 24 ′ in FIG. 3 is colored green.
The portion of the dentin attenuation part 25 'is colored in hue blue to clarify the division.
FIG. 7 is an average processing diagram of the boundary of FIG.

図8は、原画像との合成図で、前記連続階調を有する原画像(図3)と境界の平均化処理図(図7)とを合成し、前記エナメル質24及び象牙質25の部分を判りやすい任意の色彩で表示している。
図において、エナメル質24の色相は黄色と赤の混色、象牙質25の色相は黄色と緑の混色に色づけしている。
図9は、図8の画像合成の繰り返し図で、前記エナメル質24の色相は黄色と橙色に混色分離され、また象牙質25の色相は黄色と緑色に混色分離されて、前記エナメル質と象牙質の領域と、同領域内の連続階調をより鮮明に強調している。
FIG. 8 is a composite diagram with the original image. The original image having the continuous tone (FIG. 3) and the boundary averaging process diagram (FIG. 7) are combined, and the enamel 24 and dentin 25 portions are combined. Is displayed in any color that is easy to understand.
In the figure, the hue of the enamel 24 is colored yellow and red, and the hue of the dentin 25 is colored yellow and green.
FIG. 9 is a repeating view of the image composition of FIG. The quality area and continuous tone in the area are more clearly emphasized.

図10は、他の事例で、エナメル質と象牙質及び歯肉の断層画像図で、事例は健常者の生体歯牙である。図において歯肉23と歯肉の減衰部23’の色相は赤である。
したがって、被検査体21の歯肉23は赤、エナメル質24は黄色と赤の混色、及び象牙質25は黄色と緑の混色、の3種類の組織と連続階調が、それぞれ異なった色相によって表示されている。
FIG. 10 is a tomographic image diagram of enamel, dentin, and gingiva in another example, and the example is a living tooth of a healthy person. In the figure, the hue of the gingiva 23 and the gingival attenuation part 23 'is red.
Therefore, three types of tissues and continuous gradations are displayed with different hues, the gingiva 23 of the subject 21 being red, the enamel 24 being a mixture of yellow and red, and the dentin 25 being a mixture of yellow and green. Has been.

歯科用OCT装置の構成説明のブロック図。The block diagram of composition explanation of a dental OCT device. 被検査体の歯を縦方向に走査し、その時の1点を、深さ方向に連続走査したときに取得される各深度における信号強度のグラフ。The graph of the signal strength in each depth acquired when the tooth | gear of a to-be-inspected object is scanned to the vertical direction, and one point at that time is continuously scanned to the depth direction. 歯のエナメル質と象牙質の断層画像の原画像。Original image of tomographic images of tooth enamel and dentin. 深さ方向の距離による光の減衰の補正図。The correction figure of the attenuation of light by the distance of a depth direction. 図4のノイズ成分を除去した図。The figure which removed the noise component of FIG. エナメル質、象牙質各領域の任意配色による色づけと、メディアン処理による境界部分の細部凹凸の除去図。Figure of removal of detailed irregularities at the boundary by coloration of enamel and dentin areas by arbitrary color scheme and median processing. 図6の境界の平均化処理図。FIG. 7 is an average processing diagram of the boundary of FIG. 6. 原画像との合成図。Composite image with the original image. 図8の画像合成の繰り返し図。FIG. 9 is a repetition diagram of the image composition in FIG. 8. エナメル質と象牙質及び歯肉の断層画像図。A tomographic image of enamel, dentin and gingiva.

符号の説明Explanation of symbols

1:診断用プローブ
2:参照光路長走査手段
5:光学素子
6:参照光
7:コリメートレンズ
8:深さ方向走査
9:低コヒーレンス光源
10:光ファイバ
11:検出信号線
12:光ファイバカプラ
13:光検出器
14:制御信号線
15:信号処理部
16:コンピュータ
17:表示部
18:断層画像
19:横又は縦方向走査
20:信号光
21:被検査体
22:歯
23:歯肉
23’:歯肉の減衰部
24:エナメル質
24’:エナメル質の減衰部
25:象牙質
25’:象牙質の減衰部
26:歯髄
27:歯槽骨
28:空間
1: Diagnostic probe 2: Reference optical path length scanning means 5: Optical element 6: Reference light 7: Collimating lens 8: Depth scanning 9: Low coherence light source 10: Optical fiber 11: Detection signal line 12: Optical fiber coupler 13 : Photo detector 14: Control signal line 15: Signal processing unit 16: Computer 17: Display unit 18: Tomographic image 19: Horizontal or vertical scanning 20: Signal light 21: Inspected object 22: Tooth 23: Gingival 23 ': Gingival decay part 24: Enamel
24 ': Enamel attenuation part 25: Dentin 25': Dentin attenuation part 26: Pulp 27: Alveolar bone 28: Space

Claims (2)

低コヒーレンス光源からの光を、信号光と参照光とに分離して、それぞれ信号光路及び参照光路に導くようにし、前記信号光路には、前記信号光を口腔内被検査体の表面に照射し、照射点を前記被検査体表面に沿って走査する照射点走査手段が設けられ、
また、前記参照光路には,参照光路の路端で参照光を反射させる光学素子を有し、参照光の光路長を走査する参照光路長走査手段が設けられ、
前記参照光の光路長を走査して、参照光の光路長に対応する前記口腔内被検査体表面からの深層位置で反射した信号光と、前記参照光の路端で反射した参照光との光干渉に基づいて、口腔内被検査体の断層を計測する歯科用OCT装置において、
口腔内被検査体の硬組織又は軟組織あるいは、硬組織及び軟組織の各組織の断層画像を、それぞれ異なった色彩でかつ、検出信号の減衰に対応した連続階調で表わす表示装置を備えてなることを特徴とする歯科用OCT装置。
The light from the low-coherence light source is separated into the signal light and the reference light and led to the signal light path and the reference light path, respectively, and the signal light is irradiated onto the surface of the intraoral inspected object in the signal light path. An irradiation point scanning means for scanning the irradiation point along the surface of the object to be inspected,
The reference optical path includes an optical element that reflects the reference light at a path end of the reference optical path, and is provided with a reference optical path length scanning unit that scans the optical path length of the reference light.
Scanning the optical path length of the reference light, the signal light reflected at a deep layer position from the surface of the intraoral subject to be inspected corresponding to the optical path length of the reference light, and the reference light reflected at the end of the reference light In a dental OCT apparatus that measures a tomography of an intraoral inspected object based on optical interference,
Provided with a display device that displays the tomographic images of the hard tissue or soft tissue of the intraoral subject to be examined, or the tomographic images of each tissue of the hard tissue and the soft tissue in different colors and in continuous gradation corresponding to the attenuation of the detection signal. A dental OCT apparatus characterized by
口腔内被検査体が、歯牙組織又は歯周組織あるいは、歯牙組織及び歯周組織であることを特徴とする請求項1に記載の歯科用OCT装置。   The dental OCT apparatus according to claim 1, wherein the intraoral subject is a tooth tissue, a periodontal tissue, or a tooth tissue and a periodontal tissue.
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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010154934A (en) * 2008-12-26 2010-07-15 Fujifilm Corp Optical apparatus for acquiring structure information and method of processing optical interference signal
JP2012100825A (en) * 2010-11-09 2012-05-31 J Morita Tokyo Mfg Corp Dental measurement apparatus
JP2014527861A (en) * 2011-08-01 2014-10-23 シロナ・デンタル・システムズ・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング Method for recording a plurality of three-dimensional images of a dental object
JP2017099748A (en) * 2015-12-03 2017-06-08 株式会社吉田製作所 Optical coherence tomographic image display control device and program thereof
WO2017216930A1 (en) * 2016-06-16 2017-12-21 株式会社日立ハイテクノロジーズ Method for analyzing state of cells in spheroid

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004344260A (en) * 2003-05-20 2004-12-09 J Morita Tokyo Mfg Corp Dental optical diagnostic equipment
JP2006132996A (en) * 2004-11-02 2006-05-25 Shiyoufuu:Kk Fourier domain optical coherence tomography for dental measurement
JP2007000220A (en) * 2005-06-22 2007-01-11 Tohoku Univ Ultrasonic diagnostic apparatus
JP2007007410A (en) * 2005-06-30 2007-01-18 Siemens Ag Device and method for imaging lumen
WO2007060973A1 (en) * 2005-11-22 2007-05-31 Shofu Inc. Dental optical coherence tomograph

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004344260A (en) * 2003-05-20 2004-12-09 J Morita Tokyo Mfg Corp Dental optical diagnostic equipment
JP2006132996A (en) * 2004-11-02 2006-05-25 Shiyoufuu:Kk Fourier domain optical coherence tomography for dental measurement
JP2007000220A (en) * 2005-06-22 2007-01-11 Tohoku Univ Ultrasonic diagnostic apparatus
JP2007007410A (en) * 2005-06-30 2007-01-18 Siemens Ag Device and method for imaging lumen
WO2007060973A1 (en) * 2005-11-22 2007-05-31 Shofu Inc. Dental optical coherence tomograph

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010154934A (en) * 2008-12-26 2010-07-15 Fujifilm Corp Optical apparatus for acquiring structure information and method of processing optical interference signal
JP2012100825A (en) * 2010-11-09 2012-05-31 J Morita Tokyo Mfg Corp Dental measurement apparatus
JP2014527861A (en) * 2011-08-01 2014-10-23 シロナ・デンタル・システムズ・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング Method for recording a plurality of three-dimensional images of a dental object
JP2017099748A (en) * 2015-12-03 2017-06-08 株式会社吉田製作所 Optical coherence tomographic image display control device and program thereof
WO2017216930A1 (en) * 2016-06-16 2017-12-21 株式会社日立ハイテクノロジーズ Method for analyzing state of cells in spheroid
JPWO2017216930A1 (en) * 2016-06-16 2019-03-07 株式会社日立ハイテクノロジーズ Analysis method of cell state inside spheroid
US10846849B2 (en) 2016-06-16 2020-11-24 Hitachi High-Tech Corporation Method for analyzing state of cells in spheroid

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