JP2002145716A - Sunscreening cosmetic - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide a sunscreening cosmetic having sunscreening effect and bleaching effect and also high safety. SOLUTION: This sunscreening cosmetic comprises an extract from Tussilago farfafa L. and at least one ingredient selected from ultraviolet absorbers characterized by being benzophenone- or cinnamic acid-based ones and ultraviolet light scattering agents characterized by being titanium oxides or surface-treated products thereof; wherein the respective contents of the extract and the ultraviolet light absorber and/or ultraviolet light scattering agent are characterized by being 0.00001-5 wt.% on a solid basis and 0.01-15 wt.%.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a sunscreen cosmetic containing a coltsfoot extract and one or more selected from an ultraviolet absorber and an ultraviolet scattering agent. More specifically, the present invention relates to an external preparation for skin which is synergistically enhanced with the sunscreen effect of the ultraviolet absorber and the ultraviolet scattering agent by using the coltsfoot extract in combination, and which is highly safe for the skin.

[0002]

2. Description of the Related Art Ultraviolet rays have various adverse effects on human skin, such as melanin pigment formation, erythema, blisters, and reduced elasticity. In order to protect the skin from such ultraviolet rays, skin external preparations such as sunscreen cosmetics have been developed. On the other hand, in order to obtain a high ultraviolet ray prevention effect, an ultraviolet absorber and an ultraviolet scattering agent are contained at a high concentration, and their safety is a problem.

[0003]

SUMMARY OF THE INVENTION In order to solve these problems, the development of novel ultraviolet absorbers and ultraviolet scattering agents,
Formulation designs with high safety and high UV protection have been attempted.

[0004]

Means for Solving the Problems The present inventors have conducted intensive studies in view of the above-mentioned circumstances, and as a result, it has been found that by containing a coltsfoot extract and one or more selected from an ultraviolet absorber and an ultraviolet scattering agent. As a result, the sunscreen effect was synergistically enhanced, and the invention of sunscreen cosmetics with high safety was completed.

That is, the sunscreen cosmetics of the present invention
It contains one or two or more kinds of coltsfoot extracts and ultraviolet absorbers and ultraviolet scattering agents,
It is a highly safe skin external preparation that enhances the sunscreen effect synergistically.

Hereinafter, the configuration of the present invention will be described in detail.

The coltsfoot (Tussi) used in the present invention
lago farfafa L. Subcommittee winter, Asteraceae (C
ompositae), Tussilag
o) plants of Europe, North Africa, India,
Native to China.

The coltsfoot used in the present invention is selected from the whole plant of coltsfoot or flowers, leaves, stems, roots and seeds.
A portion or two or more portions are squeezed out as it is or after crushing.

The extraction solvent for the coltsfoot extract used in the present invention is not particularly limited.
Alcohols (eg, methanol, absolute ethanol,
Lower alcohols such as ethanol, or polyhydric alcohols such as propylene glycol and 1,3-butylene glycol), ketones such as acetone, esters such as ethyl ether, acetonitrile and ethyl acetate, and organics such as xylene, benzene and chloroform. One or more selected from solvents can be used in combination,
Further, the respective solvent extracts may be combined.

[0010] The extraction method is not particularly limited, but may be, for example, at room temperature and normal pressure or lower than the boiling point of the solvent. After the extraction, the extract may be filtered or purified using an ion exchange resin, and if necessary, a treatment such as decolorization or deodorization may be added to the extent that the effect of the extract is not affected. Bleaching,
Activated carbon columns or the like may be used as a treatment means for deodorization or the like, and ordinary means generally applied to extracts may be arbitrarily selected. The extract is in the form of a solution, paste,
It may be in the form of a gel or powder.

The coltsfoot extract used in the present invention is preferably one in which the extraction solvent is one or a combination of two or more selected from water, ethanol, propylene glycol and 1,3-butylene glycol. As a product, "Butterfly Poppy Extract", which is a 30% by weight 1,3-butylene glycol solution extracted at room temperature, manufactured by Ichimaru Falcos Co., Ltd. may be mentioned.

The content of the coltsfoot extract used in the present invention is not particularly limited, but is preferably 0.00001 to 5% by weight as a solid content.
If the amount is less than 0.00001% by weight, a synergistic sunscreen effect and high safety may not be expected in some cases. It is possible to contain more than 5% by weight. Not recognized and not economic.

The ultraviolet absorbent used in the present invention is not particularly limited as long as it has an ultraviolet absorbing ability. Salicylic acid-based ultraviolet absorbent, cinnamic acid-based ultraviolet absorbent, benzophenone-based ultraviolet absorbent, benzoic acid-based ultraviolet absorbent UV absorbers and the like, specifically, menthyl salicylate, amyl salicylate, homomenthyl salicylate, phenyl salicylate, octyl salicylate, salicylic acid UV absorbers such as benzyl salicylate, octyl cinnamate, ethyl-4-isopropyl cinnamate, Ethyl-
2,4-diisopropylcinnamate, methyl-2,4
-Diisopropylcinnamate, propyl-4-methoxycinnamate, isopropyl-4-methoxycinnamate isoamyl-4-methoxycinnamate, 2-ethylhexyl-4-methoxycinnamate, 2-ethoxyethyl-4-methoxycinnamate, cyclohexyl −
4-methoxycinnamate, ethyl-α-cyano-β-
Cinnamic acid ultraviolet absorbers such as phenylcinnamate, glyceryl mono-2-ethylhexanoyl-diparamethoxycinnamate, 2-ethylhexyl-α-cyano-β-phenylcinnamate, 2,4-dihydroxybenzophenone, 2, 2'-dihydroxy-4-methoxybenzophenone, 2,2'-dihydroxy-4,4'-dimethoxybenzophenone, 2,2'4,4'-tetrahydroxybenzophenone, 2-hydroxy-4-methoxybenzophenone, 2-hydroxy -4-methoxy-4'-
Benzophenone ultraviolet absorbers such as methylbenzophenone, 2-hydroxy-4-methoxybenzophenone-5-sulfonate, 4-phenylbenzophenone, 2-hydroxy-4-n-octoxybenzophenone, and 4-hydroxy-3-carboxybenzophenone , P-aminobenzoic acid, glyceryl-p-aminobenzoic acid, ethyldihydroxypropyl-p-aminobenzoic acid, ethyl N-dimethyl-p-aminobenzoate, N-dimethyl-p-aminobenzoic acid butyl, N-dimethyl Benzoic acid-based ultraviolet absorbers such as -amyl p-aminobenzoate and octyldimethyl-p-aminobenzoic acid, and others, urocanic acid, ethyl urocanate, 4-methoxy-4'-t-butyldibenzoylmethane, and homomenthyl- N-acetylanthranilate, 2,2 ' Hydroxy-5-methylphenyl benzotriazole.

Specific examples of the ultraviolet scattering agent used in the present invention include metal oxides such as titanium oxide, zinc oxide, cerium oxide, and zirconium oxide. Alternatively, a surface treatment such as silicone, fluorine, fatty acid, alginic acid, silica, or silane treatment may be performed.

The ultraviolet absorber and ultraviolet scattering agent used in the present invention are selected from the above components, and are preferably benzophenone ultraviolet absorbers, cinnamic acid ultraviolet absorbers, titanium oxide and surface-treated products thereof. There are, for example, 2-hydroxy-4-methoxybenzophenone which is a benzophenone type ultraviolet absorber, 2-ethylhexyl-4-methoxycinnamate which is a cinnamic acid type ultraviolet absorber, titanium oxide, and fine particle titanium oxide which is a surface-treated product thereof Is mentioned.

These ultraviolet absorbers and ultraviolet scattering agents are:
One or more kinds may be contained in order to improve the prevention of ultraviolet rays or ensure the stability of the preparation, and the content is not particularly limited, but is 0.01 to 15% by weight. If the content is less than 0.01% by weight, the effect of preventing ultraviolet light may not be expected in some cases. It is possible to contain more than 15% by weight. Is not recognized and is not economical.

The sunscreen cosmetic of the present invention may contain, in addition to the above essential components, various components used in ordinary cosmetics, quasi-drugs, pharmaceuticals, and the like, such as oily components, emulsifiers, humectants, thickeners, and medicinal effects. Components, preservatives, pigments, powders, pH adjusters, antioxidants, fragrances, and the like can be appropriately blended.

Specifically, the oily components include, for example, liquid paraffin, vaseline, microcrystalline wax, squalane, jojoba oil, beeswax, carnauba wax, lanolin, olive oil, coconut oil, higher alcohols,
Examples include fatty acids, esters of higher alcohols and fatty acids, and silicone oils. Examples of the emulsifier include nonionic surfactants such as polyoxyethylene alkyl ether, polyoxyethylene fatty acid ester, polyoxyethylene sorbitan fatty acid ester, sorbitan fatty acid ester, glycerin fatty acid ester, polyglycerin fatty acid ester, and polyoxyethylene hydrogenated castor oil. And anionic surfactants such as sodium stearoyl lactate; amphoteric surfactants such as soybean phospholipid; and cationic surfactants such as alkyltrimethylammonium chloride. Examples of the humectant include glycerin, sorbitol, xylitol, maltitol, propylene glycol, polyethylene glycol, 1,3-butylene glycol and the like. Examples of the thickener include carboxyvinyl polymer, xanthan gum, methylcellulose, polyvinylpyrrolidone, gelatin, clay minerals such as bentonite, and the like. Examples of the medicinal component include various vitamins and derivatives thereof, allantoin, glycyrrhizic acid and derivatives thereof, and various animal and plant extracts.

The sunscreen cosmetics of the present invention can be produced by a known method and are not limited to general skin cosmetics, but include quasi-drugs, topical medicines and the like. The mold can be arbitrarily selected according to the purpose, and may be in the form of a cream, an emulsion, a liquid, a gel, an ointment, a pack, a stick, a powder, or the like.

[0020]

The sunscreen cosmetic of the present invention relates to an external preparation for skin characterized by containing a coltsfoot extract and one or more ultraviolet absorbers and ultraviolet scattering agents. Compared with commonly used sunscreen cosmetics, it is a skin external preparation that has a remarkably excellent sunscreen effect and high safety.

Comparative Examples 1-5, Examples 1-3, Table 2 in Table 1
The samples shown in Examples 4 to 15 were prepared, the transmittance was measured, and the human primary irritation test was performed. The results are shown in Tables 1 and 2. The compounding amount is% by weight. Prior to the examples, a method for producing a sample used in the present invention, a method for measuring transmittance, and a method for testing safety will be described.

(Production method of sample) The components of Examples and Comparative Examples shown in Tables 1 to 3 are dissolved and mixed at 75 ° C., and emulsified under the same conditions using a shearing force by a homogenizer. Thereafter, each sample was obtained by cooling to room temperature while continuing stirring.

(Measurement Method of Transmittance) A 1.0% by weight aqueous solution of each of the samples shown in Tables 1 and 2 was prepared, and 0.1% aqueous solution was prepared on a quartz glass plate.
The thickness was measured in a sandwich with a thickness of mm. The measurement is
Wavelength 360 nm (ultraviolet ray A wave) with a spectrophotometer, 310
The transmittance in nm (ultraviolet B wave) was measured, and the average value was taken as the average transmittance. From the average transmittance, the formula 1
I asked for it.

UV protection rate (%) = (1−average transmittance) × 100 Equation 1

(Test Method of Safety) As a safety test,
A patch test was performed on 20 humans. A 10% by weight aqueous solution of each of the samples shown in Tables 1 and 2 was prepared and attached for 24 hours using a fin chamber (manufactured by EPITEST) as an attaching material. The number of persons who recognized erythema 1 hour after peeling was counted.

[0026]

[Table 1]

[0027]

[Table 2]

As described above, according to the present invention, by containing a coltsfoot extract and one or more selected from an ultraviolet absorber and an ultraviolet scattering agent, the sunscreen effect is remarkably high. It becomes possible to provide a skin external preparation that is highly safe for the skin.

[0029]

EXAMPLES The present invention will be described below in more detail with reference to Examples, but it should not be construed that the invention is limited thereto.

Example 16 Sunscreen Moisturizing Cream A Squalane 10.0% by Weight Adsorbed and Purified Lanolin 4.5 Vaseline 4.5 2-Hydroxy-4-methoxybenzophenone 3.0 Stearyl Alcohol 3.0 POE (20) Monostearic Acid Sorbitan 2.2 POE (20) cetyl ether 2.0 Perfume Appropriate B Butterfly poppy extract (* 1) 10.0 Polyethylene glycol 8.0 Preservative Appropriate pH adjuster Appropriate Purified water Residue

After the raw material of the oil phase of A and the raw material of the aqueous phase of B are heated to 75 ° C. and completely dissolved, the oil phase is mixed with the aqueous phase, emulsified, and cooled to room temperature. The obtained cream was a good emulsion having high sunscreen effect and high safety.

Example 17 Sunscreen Whitening Emulsion A Neopentyl glycol dicaprate 7.0% by weight isononyl isononanoate 7.0 2-Ethylhexyl-4-methoxycinnamate 7.0 Fine particle titanium oxide 6.0 POE (20) olein Glyceryl acid 2.0 Perfume Appropriate amount B 1,3-butylene glycol 5.0 Water-soluble placenta extract 5.0 Futandandelion extract (normal temperature extraction, solid content 2%) 1.0 Carboxyvinyl polymer 0.1 AMPD 0.05 Preservative Agent qs purified water residue

After the raw material of the oil phase of A and the raw material of the aqueous phase of B are heated to 75 ° C. and completely dissolved, the oil phase is mixed with the aqueous phase, emulsified using a homogenizer, and cooled to room temperature. The obtained emulsion was an emulsion having both a sunscreen effect and a whitening effect, and was also highly safe. Also,
The feeling of use was refreshing and non-sticky.

Example 18 Sunscreen Body Lotion Ethanol 10.0% by weight Coltsfoot extract (ethanol extraction, solid content 1%) 5.0 2-Ethylhexyl paradimethylaminobenzoate 5.0 Dipropylene glycol 5.0 POE (9) Lauryl ether 0.5 l-menthol 0.1 perfume proper amount preservative proper amount pH adjuster proper amount purified water residue

At room temperature, all components are mixed and completely dissolved. The obtained lotion had a high sunscreen effect and was excellent in safety. In addition, the feeling of use was refreshing and comfortable without stickiness.

Continued on the front page (51) Int.Cl. ⁷ Identification symbol FI Theme coat II (Reference) A61K 7/48 A61K 7/48 (72) Inventor Jiro Kitahara 2-7 Tomicho, Nishi-ku, Nagoya-shi, Aichi Japan Menard cosmetics Research Institute, Inc. (72) Inventor Satoru Nakata 2-7 Torimicho, Nishi-ku, Nagoya-shi, Aichi Japan Menard Co., Ltd. Research Institute F-term (reference) 4C083 AA072 AA111 AA112 AB241 AB242 AC022 AC072 AC102 AC122 AC182 AC341 AC342 AC352 AC392 AC422 AC432 AC442 AC471 AC472 AC482 AD042 AD092 AD352 AD512 AD532 BB46 CC04 CC05 CC19 DD23 DD31 EE17

Claims (4)

[Claims] 1. A coltsfoot (Tussilago fa)
rfafa L. Sub-section winter) A sunscreen cosmetic comprising an extract and one or more selected from ultraviolet absorbers and ultraviolet scattering agents. 2. The sunscreen cosmetic according to claim 1, wherein the ultraviolet absorber is a benzophenone-based ultraviolet absorber or a cinnamic acid-based ultraviolet absorber. 3. The sunscreen cosmetic according to claim 1, wherein the ultraviolet scattering agent is titanium oxide or a surface-treated product thereof. 4. The content of coltsfoot extract is 0.00001 to 5% by weight as a solid content, and the content of one or more selected from ultraviolet absorbers and ultraviolet scattering agents is 0.01 to 15%. 2. The composition according to claim 1, wherein the content is% by weight.
The whitening cosmetic according to claim 3.