JP2001515375A - Intravascular blood pump - Google Patents

Intravascular blood pump

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Publication number
JP2001515375A
JP2001515375A JP53581797A JP53581797A JP2001515375A JP 2001515375 A JP2001515375 A JP 2001515375A JP 53581797 A JP53581797 A JP 53581797A JP 53581797 A JP53581797 A JP 53581797A JP 2001515375 A JP2001515375 A JP 2001515375A
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Japan
Prior art keywords
pump
blood pump
blood
intravascular blood
unit
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Ceased
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JP53581797A
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Japanese (ja)
Inventor
ラウ、ギュンター
ロイル、ヘルムト
シエス、トルステン
Original Assignee
インペラ カーディオテヒニック ゲゼルシャフト ミット ベシュレンクター ハフツング
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Publication of JP2001515375A publication Critical patent/JP2001515375A/en
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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/80Constructional details other than related to driving
    • A61M60/802Constructional details other than related to driving of non-positive displacement blood pumps
    • A61M60/833Occluders for preventing backflow
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/10Location thereof with respect to the patient's body
    • A61M60/122Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body
    • A61M60/126Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body implantable via, into, inside, in line, branching on, or around a blood vessel
    • A61M60/135Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body implantable via, into, inside, in line, branching on, or around a blood vessel inside a blood vessel, e.g. using grafting
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/20Type thereof
    • A61M60/205Non-positive displacement blood pumps
    • A61M60/216Non-positive displacement blood pumps including a rotating member acting on the blood, e.g. impeller
    • A61M60/237Non-positive displacement blood pumps including a rotating member acting on the blood, e.g. impeller the blood flow through the rotating member having mainly axial components, e.g. axial flow pumps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/40Details relating to driving
    • A61M60/403Details relating to driving for non-positive displacement blood pumps
    • A61M60/408Details relating to driving for non-positive displacement blood pumps the force acting on the blood contacting member being mechanical, e.g. transmitted by a shaft or cable
    • A61M60/411Details relating to driving for non-positive displacement blood pumps the force acting on the blood contacting member being mechanical, e.g. transmitted by a shaft or cable generated by an electromotor
    • A61M60/416Details relating to driving for non-positive displacement blood pumps the force acting on the blood contacting member being mechanical, e.g. transmitted by a shaft or cable generated by an electromotor transmitted directly by the motor rotor drive shaft
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/80Constructional details other than related to driving
    • A61M60/855Constructional details other than related to driving of implantable pumps or pumping devices
    • A61M60/857Implantable blood tubes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/80Constructional details other than related to driving
    • A61M60/855Constructional details other than related to driving of implantable pumps or pumping devices
    • A61M60/861Connections or anchorings for connecting or anchoring pumps or pumping devices to parts of the patient's body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/10Location thereof with respect to the patient's body
    • A61M60/122Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body
    • A61M60/126Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body implantable via, into, inside, in line, branching on, or around a blood vessel
    • A61M60/148Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body implantable via, into, inside, in line, branching on, or around a blood vessel in line with a blood vessel using resection or like techniques, e.g. permanent endovascular heart assist devices

Abstract

(57)【要約】 本明細書で提示する血管内血液ポンプは、駆動ユニット(11)、およびそれに緊密に接続されたポンプ・ユニット(12)を有し、血液ポンプはカテーテル(13)に接続され、それを血管(10)に挿入できるようにする。ポンブ・ユニット(12)の管状ケーシング(15)には、吸引側(21)を放出側から分離し、したがってポンプが迂回されるのを防止する遮断装置(20)が取り付けられる。 (57) Abstract: The intravascular blood pump presented herein has a drive unit (11) and a pump unit (12) tightly connected thereto, the blood pump being connected to a catheter (13). So that it can be inserted into the blood vessel (10). The tubular casing (15) of the pump unit (12) is fitted with a shut-off device (20) that separates the suction side (21) from the discharge side, thus preventing the pump from being bypassed.

Description

【発明の詳細な説明】 血管内血液ポンプ 本発明はモータを含む駆動ユニットと、駆動ユニットに緊密に接続されたポン プ・ユニットとを備える血管内血液ポンプに関し、ポンプ・ユニットは管状ケー シングと、その中で回転するよう配置された回転翼とを備える。上記のタイプの ポンプは、刊行物「The International Journal of Artificial Organs」,Vol. 18,No.5(1995年)の273−285頁から知られる。ポンプは、血管を穿孔 し、身体の脈管系に導入し、心臓または血液を配送すべき別の部位へ進める。 米国特許第4,969,865号、欧州特許第0 157 871 B1号お よび欧州特許第0 397 668 B1号は、既知の別の血管内血液ポンプに ついて記述しているが、ここではポンプ・ユニットのみを血流内で前進させ、駆 動ユニットは体外にあり、可撓軸を介してポンプ・ユニットに接続される。 欧州特許第0 157 859 B1号から知られる血液ポンプでは、駆動ユ ニットとポンプ・ユニットを互いに一体に組み合わせる。このポンプは体内移植 には適しているが、侵入を最小にする外科的介入によって体内に導入する血管内 血液ポンプとしては有用ではない。 血管内血液ポンプは、血管の閉塞を回避するのに十分なほど小さい外径でなけ ればならない。最大許容外径は約7mmの範囲である。駆動ユニットをポンプ・ ユニットの近傍に配置すると、構造設計による制約のために駆動ユニットの性能 が制限される。したがって、ポンプの性能を最大限に利用し、かつ性能および流 量の損失を最小限に抑えることが肝要である。 ドイツ特許第37 05 637 A1号によると、環状バルーンを使用する ことにより、カテーテルに沿った流路を閉塞する可能性がある。 血管内で、特に大動脈外でも高い効率で使用されるようになされた血管内血液 ポンプを提供することが、本発明の目的である。 上記の目的は、請求項1の主題によって解決される。 本発明の血管内血液ポンプでは、駆動ユニットをポンプ・ユニットと組み合わ せて、一体構造ユニットを形成する。すなわち、両方のユニットを一緒に血管に 挿入する。個々の器官の上流側の部位で、血液ポンプがその器官の供給血管に挿 入され、したがって、中心吸引口を備えたポンプ・ユニットが流れ方向に見て駆 動ユニットの前に配置される。ポンプ・ユニットにはポンプ・ケーシングの外側 に沿って流れの短絡を防止する遮断装置を設ける。これによって、ポンプの排出 側からの流体/血液がポンプ・ケーシングを通過できなくなり、したがって取入 れ口に到達する。吸引された血液はすべて流れの方向に駆動ユニットを通って流 れるような向きになる。したがって、請求の範囲に記載のポンプの適用可能性は 、大動脈弁が遮断装置として作用することができる大動脈への挿入に限定される ものではない。 吸引口が血管の中心位置にあるので、ポンプが吸引力によって血管に付着して しまう危険性は、最小限である。血液流は完全に駆動ユニットを通って流れるの で、血管の直径がポンプ・ユニットまたは駆動ユニットの直径にほぼ対応する場 合でも、ポンプで蓄積された圧力のせいで弾性の血管が開いたままにならないよ う保護される。さらに、モータと血管の間のフロー・オフ流は、駆動ユニットで 発生した熱を散逸させ、(41℃より高い)過度の表面温度による血液の損傷が 発生しない。センタリング装置を駆動ユニットの外周から突き出すように配置す ると有利である。センタリング装置は、一方ではフロー・オフ通路を開いたまま にし、他方では駆動ユニットを血管の中心に配置するために設けられる。さらに 、センタリング装置は遮断装置とあいまって、血管中でのポンプ全体の回転およ び軸方向の転位を防止する。 本発明の実施形態を、図面に関して以下でさらに詳細に説明する。 図1は、血管内に配置された脈管内血管ポンプの組織図である。 図2は、血管内に配置された血液ポンプの第2の実施形態を示す図である。 図1では、たとえば動脈などの血管10内に配置された状態の血液ポンプを示 す。血液ポンプは、互いに緊密に接続され、互いに距離をおいて配置されたモー タ・ユニット11およびポンプ・ユニット12を備える。駆動ユニット11は駆 動モータを収容する。駆動ユニット11の後端は、モータ14用の電源線および 制御線が通るカテーテル13に接続される。 ポンプ・ユニット12には、ロータと同軸に配置されて一方端に形成された吸 引開口部16を有する管状ポンプ・ケーシング15を備える。回転翼17は、回 転できるようにポンプ・ケーシング15内に配置され、流れ方向に広がるハブ1 8と、ハブ18から径方向に延びるブレードとを備える。ハブ18はモータ14 の出力軸上に配置されるか、あるいは自由回転できるように支持され、磁気継手 を介してモータの出力軸に結合される。 モータ14およびポンプ・ケーシング15は、ほぼ同じ直径である。この直径 は5ないし8mmの範囲であり、したがって血液ポンプは血管を遮断しない。ポ ンプ・ケーシング15を出る血流は、次にモータ14の外表面に沿って流れる。 ほぼ円錐台形の可撓密封スクリーンを備えた拡張可能な遮断装置20が、ポン プ・ケーシング15の外周に取り付けられる。密封スクリーンの小さい方の端部 はポンプ・ケーシングに取り付けられ、大きい方の端部は外側に折れて、血管1 0の壁に突き当たるか、つぶれ、したがって外側でポンブ・ケーシング15に突 き当たるようになっている。遮断装置20を形成する可撓密封スクリーンは、逆 止め弁の方式で作用する。吸引開口部16の上流側の区域21の圧力がポンプの 排出口における圧力より低いと、密封スクリーンが拡張して、ポンプ・ケーシン グと血管壁との間の環状スペースを遮断する。このようにして、血液はポンプの 出口側22から取入れ側21へと逆流しない。したがって、血流はすべて強制的 にモータ14に沿って流れる。 血管10内で駆動ユニット11の中心位置を安定させるため、駆動ユニット1 1には、駆動ユニット11の外周から延びるセンタリング装置23を設け、外側 に向かって先細のばね様リブを突き出すように設ける。 図2による実施形態では、前方に突き出し、中心で血管内に到達して端部に血 液を取り入れる開口部を設けた吸引ホース25に、ポンプ・ケーシング15を接 続する。吸引ホース25は、円筒形のポンプ・ケーシング15に密封状態で取り 付けられ、これを前方に延長する。 図2による遮断装置20aは、ポンプ・ケーシング15または吸引ホース25 に取り付けた環状バルーンを備える。このバルーンはカテーテル13の内腔に接 続され、したがって気体または液体によって体外で膨張させることができる。バ ルーンは血液の逆流を防止し、ポンプ・ユニット12および吸引ホース25を血 管の中心に配置する。DETAILED DESCRIPTION OF THE INVENTION                             Intravascular blood pump   The present invention relates to a drive unit including a motor, and a pump tightly connected to the drive unit. Blood pump with a pump unit, the pump unit comprising a tubular casing. A shing and a rotor arranged to rotate therein. Of the above type Pumps are published in the publication "The International Journal of Artificial Organs", Vol. 18, No. 5 (1995), pages 273-285. Pump perforates blood vessels To the body's vasculature and to the heart or another location where blood is to be delivered.   U.S. Pat. No. 4,969,865, EP 0 157 871 B1 and And EP 0 397 668 B1 describe another known intravascular blood pump. In this case, only the pump unit is advanced in the bloodstream, The moving unit is external to the body and is connected to the pump unit via a flexible shaft.   In a blood pump known from EP 0 157 859 B1, a drive unit is known. Combine the knit and pump unit together. This pump is implanted in the body Is suitable for intravascular treatment, but is introduced into the body by surgical intervention to minimize invasion It is not useful as a blood pump.   Intravascular blood pumps must have an outer diameter small enough to avoid occlusion of the vessel. I have to. The maximum allowable outer diameter is in the range of about 7mm. Drive unit with pump When placed near the unit, the performance of the drive unit may be reduced due to structural design constraints. Is limited. Therefore, make full use of the performance of the pump, and It is important to minimize loss of volume.   According to DE 37 05 637 A1, an annular balloon is used. This can block the flow path along the catheter.   Intravascular blood adapted to be used with high efficiency inside blood vessels, especially outside the aorta It is an object of the present invention to provide a pump.   The above object is solved by the subject matter of claim 1.   In the intravascular blood pump of the present invention, the drive unit is combined with the pump unit. Then, an integral structure unit is formed. That is, both units together in a blood vessel insert. At a site upstream of an individual organ, a blood pump is inserted into the supply vessel of that organ. The pump unit with central suction is thus driven in the flow direction. It is arranged in front of the moving unit. Pump unit outside pump casing A cut-off device is provided to prevent a short circuit in the flow along. This allows the pump to drain Fluid / blood from the side cannot pass through the pump casing and therefore Reach the mouth. All aspirated blood flows through the drive unit in the direction of flow. Orientation. Therefore, the applicability of the claimed pump is Limited to insertion into the aorta, where the aortic valve can act as a blocking device Not something.   Since the suction port is located at the center of the blood vessel, the pump adheres to the blood vessel by the suction force. The danger of losing is minimal. The blood flow flows completely through the drive unit Where the diameter of the blood vessel approximately corresponds to the diameter of the pump or drive unit Even if the pressure builds up in the pump, the elastic vessels will not stay open Be protected. In addition, the flow-off flow between the motor and the blood vessels is Dissipates the heat generated and damages the blood from excessive surface temperatures (above 41 ° C) Does not occur. Arrange the centering device so that it protrudes from the outer periphery of the drive unit. This is advantageous. Centering device, on the other hand, keeps the flow-off passage open And, on the other hand, for positioning the drive unit in the center of the blood vessel. further The centering device, in conjunction with the shut-off device, rotates and rotates the entire pump in the blood vessel. And axial dislocations are prevented.   Embodiments of the present invention are described in further detail below with reference to the drawings.   FIG. 1 is a tissue diagram of an intravascular vascular pump placed in a blood vessel.   FIG. 2 is a diagram showing a second embodiment of a blood pump disposed in a blood vessel.   FIG. 1 shows a blood pump placed in a blood vessel 10 such as an artery. You. Blood pumps are closely connected to each other and spaced apart from each other. And a pump unit 12. The drive unit 11 is Accommodates the dynamic motor. The rear end of the drive unit 11 has a power line for the motor 14 and It is connected to a catheter 13 through which a control line passes.   The pump unit 12 is provided coaxially with the rotor and formed at one end. It comprises a tubular pump casing 15 having a pull opening 16. The rotating wings 17 Hub 1 which is arranged in a pump casing 15 so as to be able to 8 and a blade extending radially from the hub 18. The hub 18 is a motor 14 The magnetic coupling is mounted on the output shaft of the To the output shaft of the motor.   Motor 14 and pump casing 15 are approximately the same diameter. This diameter Is in the range of 5 to 8 mm, so that the blood pump does not block the blood vessels. Po Blood flow exiting the pump casing 15 then flows along the outer surface of the motor 14.   An expandable shut-off device 20 having a generally frusto-conical flexible sealing screen is provided. It is attached to the outer periphery of the loop casing 15. Small end of sealing screen Is attached to the pump casing, the larger end bends outward and the vessel 1 0 crushes or crushes the wall and therefore collides with the pump casing 15 on the outside. It has come to hit. The flexible sealing screen forming the blocking device 20 is inverted It works in the manner of a stop valve. The pressure in the area 21 upstream of the suction opening 16 is Below the pressure at the outlet, the sealing screen expands and the pump casing Block the annular space between the wall and the vessel wall. In this way, blood is pumped There is no backflow from the outlet side 22 to the intake side 21. Therefore, all blood flow is forced Flows along the motor 14.   To stabilize the center position of the drive unit 11 in the blood vessel 10, the drive unit 1 1 is provided with a centering device 23 extending from the outer periphery of the drive unit 11, The tapered spring-like rib is provided so as to protrude toward.   In the embodiment according to FIG. 2, it projects forward, reaches the blood vessel at the center and has The pump casing 15 is connected to a suction hose 25 having an opening for taking in a liquid. Continue. The suction hose 25 is sealed in the cylindrical pump casing 15. And extend it forward.   The shut-off device 20a according to FIG. And an annular balloon attached to the. This balloon contacts the lumen of the catheter 13. And can thus be expanded outside the body by a gas or liquid. Ba The rune prevents the backflow of blood and connects the pump unit 12 and suction hose 25 with blood. Place in the center of the tube.

───────────────────────────────────────────────────── フロントページの続き (72)発明者 シエス、トルステン ドイツ連邦共和国 エーヘン 52072 ボ イラルトシュタイナー フェルト 31番────────────────────────────────────────────────── ─── Continuation of front page    (72) Inventors Cies, Torsten             Germany Achen 52072 Bo             Iralto Steiner Felt No. 31

Claims (1)

【特許請求の範囲】 1.モータ(14)を含む駆動ユニット(11)と、駆動ユニット(11)に緊 密に接続されたポンプ・ユニット(12)とを備え、ポンプ・ユニット(12) が管状ポンプ・ケーシング(15)と、ポンプ・ケーシング(15)内で回転す るように配置された回転翼(34)とを備える血管内血液ポンプであって、ポン プ・ケーシング(15)の外側で流路を遮断する拡張可能な遮断装置(20;2 0a)をさらに備える血液ポンプ。 2.駆動ユニット(1)が、モータ(14)の外周から突き出したセンタリング 装置(23)を備えることを特徴とする、請求項1に記載の血管内血液ポンプ。 3.遮断装置(20;20a)がポンプ・ケーシング(15)に装着されること を特徴とする、請求項1または2に記載の血管内血液ポンプ。 4.ポンプ・ケーシング(15)が、それに挿入された吸引ホース(25)を有 し、遮断装置(20a)がポンプ・ケーシング(15)および/または吸引ホー ス(25)を囲むように配置されることを特徴とする、請求項1ないし3のいず れか一項に記載の血管内血液ポンプ。 5.遮断装置(20a)が環状バルーンを備えることを特徴とする、請求項1な いし4のいずれか一項に記載の血管内血液ポンプ。 6.遮断装置(20)が逆止め弁として作用する密封スクリーンを備えることを 特徴とする、請求項1ないし4のいずれか一項に記載の血管内血液ポンプ。 7.遮断装置(20;20a)が、径方向、軸方向、および円周方向にポンプ・ ユニツト(12)を固定する機能を実行することを特徴とする、請求項1ないし 6のいずれか一項に記載の血管内血液ポンプ。[Claims] 1. A drive unit (11) including a motor (14); A pump unit (12) comprising a closely connected pump unit (12). Rotates in the tubular pump casing (15) and in the pump casing (15) An intravascular blood pump comprising: Expandable shut-off device (20; 2) for shutting off the flow path outside the casing (15) A blood pump further comprising 0a). 2. Centering in which the drive unit (1) projects from the outer periphery of the motor (14) Intravascular blood pump according to claim 1, characterized in that it comprises a device (23). 3. The shut-off device (20; 20a) is mounted on the pump casing (15). The intravascular blood pump according to claim 1 or 2, characterized in that: 4. A pump casing (15) having a suction hose (25) inserted therein; And the shut-off device (20a) is connected to the pump casing (15) and / or the suction hood. 4. The arrangement according to claim 1, wherein the arrangement is made so as to surround the An intravascular blood pump according to claim 1. 5. The device according to claim 1, characterized in that the blocking device (20a) comprises an annular balloon. The intravascular blood pump according to any one of the chairs 4. 6. That the shut-off device (20) comprises a sealing screen acting as a check valve; An intravascular blood pump according to any one of claims 1 to 4, characterized in that it is characterized in that: 7. The shut-off device (20; 20a) is provided with a pump, radially, axially and circumferentially. 3. The method according to claim 1, wherein the function of fixing the unit is performed. The intravascular blood pump according to any one of claims 6 to 10.
JP53581797A 1996-04-04 1997-04-02 Intravascular blood pump Ceased JP2001515375A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19613565.6 1996-04-04
DE19613565A DE19613565C1 (en) 1996-04-04 1996-04-04 Intravasal blood pump with drive motor
PCT/EP1997/001660 WO1997037697A1 (en) 1996-04-04 1997-04-02 Intravascular blood pump

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JP2001515375A true JP2001515375A (en) 2001-09-18

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EP (1) EP0929327A1 (en)
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CA (1) CA2250993A1 (en)
DE (1) DE19613565C1 (en)
WO (1) WO1997037697A1 (en)

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JP2010519001A (en) * 2007-02-27 2010-06-03 ミラコー メディカル システムズ ゲーエムベーハー Catheter that helps the heart work
JP2015500666A (en) * 2011-08-29 2015-01-08 ミネトロニクス, インコーポレイテッド Expandable vascular pump
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Also Published As

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CA2250993A1 (en) 1997-10-16
DE19613565C1 (en) 1997-07-24
EP0929327A1 (en) 1999-07-21
WO1997037697A1 (en) 1997-10-16

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