JP2000005152A - Diabetes diagnostic unit - Google Patents

Diabetes diagnostic unit

Info

Publication number
JP2000005152A
JP2000005152A JP10175559A JP17555998A JP2000005152A JP 2000005152 A JP2000005152 A JP 2000005152A JP 10175559 A JP10175559 A JP 10175559A JP 17555998 A JP17555998 A JP 17555998A JP 2000005152 A JP2000005152 A JP 2000005152A
Authority
JP
Japan
Prior art keywords
light
light emitting
partial pressure
blood
diabetes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP10175559A
Other languages
Japanese (ja)
Inventor
Taketoshi Sato
武年 佐藤
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Panasonic Holdings Corp
Original Assignee
Matsushita Electric Industrial Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Matsushita Electric Industrial Co Ltd filed Critical Matsushita Electric Industrial Co Ltd
Priority to JP10175559A priority Critical patent/JP2000005152A/en
Publication of JP2000005152A publication Critical patent/JP2000005152A/en
Pending legal-status Critical Current

Links

Landscapes

  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)

Abstract

PROBLEM TO BE SOLVED: To accurately diagnose whether or not a person suffers from diabetes from the difference between the blood oxygen concentration at a portion having a high oxygen partial pressure of a blood vessel and the blood oxygen concentration at a portion having a low oxygen partial pressure of the blood vessel based on the signals of light receiving means without collecting blood and to display the diagnosis result on a display means. SOLUTION: A first light emitting means 1, a second light emitting means 3, a first light receiving means 2 and a second light receiving means 4 are used. Whether or not a person suffers from diabetes is accurately diagnosed from the difference between the blood oxygen concentration at a portion having a high oxygen partial pressure of a blood vessel and the blood oxygen concentration at a portion having a low oxygen partial pressure of the blood vessel based on the signals of the light receiving means 2, 4 without collection blood, and the diagnosis result is displayed on a display means 10. The first light emitting means 1 and the second light emitting means 3 emit the light with two wavelengths of 680 nm and 830 nm, a semiconductor laser can be used for them, and they can be miniaturized.

Description

【発明の詳細な説明】DETAILED DESCRIPTION OF THE INVENTION

【0001】[0001]

【発明の属する技術分野】本発明は、糖尿病の可能性を
簡単に判断できる糖尿病診断器とその使用方法に関する
ものである。
BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a diabetic diagnostic apparatus which can easily determine the possibility of diabetes and a method of using the same.

【0002】[0002]

【従来の技術】従来、糖尿病の判断は、健康診断の際の
採血血液を測定することによって血糖値の測定と共に行
っている。
2. Description of the Related Art Conventionally, the judgment of diabetes is made together with the measurement of blood sugar level by measuring blood collected during a health checkup.

【0003】[0003]

【発明が解決しようとする課題】しかしこの方法は、個
々の測定毎に比較的多量の血液を必要とし、かなりの苦
痛を伴うものである。
However, this method requires a relatively large amount of blood for each individual measurement and is quite painful.

【0004】[0004]

【課題を解決するための手段】本発明は、第1の発光手
段と第2の発光手段と、第1の受光手段と第2の受光手
段とを使用し、前記各受光手段の信号から血管の酸素分
圧の高い部位での血中酸素濃度と血管の酸素分圧の低い
部位での血中酸素濃度との差から、採血を伴うことな
く、糖尿病であるかどうかを正確に診断し表示手段に診
断結果を表示する糖尿病診断器としている。
According to the present invention, a first light emitting means, a second light emitting means, a first light receiving means and a second light receiving means are used, and a blood vessel is obtained from a signal of each light receiving means. The difference between the blood oxygen concentration at the site with a high oxygen partial pressure and the blood oxygen concentration at the site with a low oxygen partial pressure in the blood vessel accurately diagnoses and displays whether or not the patient has diabetes without blood sampling. It is a diabetes diagnostic device that displays the diagnostic results on the means.

【0005】[0005]

【発明の実施の形態】請求項1に記載した発明は、第1
の発光手段と第2の発光手段と、第1の受光手段と第2
の受光手段とを使用し、前記各受光手段の信号から血管
の酸素分圧の高い部位での血中酸素濃度と血管の酸素分
圧の低い部位での血中酸素濃度との差から、採血を伴う
ことなく、糖尿病であるかどうかを正確に診断し表示手
段に診断結果を表示する糖尿病診断器としている。
DESCRIPTION OF THE PREFERRED EMBODIMENTS The first aspect of the present invention is a first aspect of the present invention.
Light emitting means, second light emitting means, first light receiving means and second light emitting means.
The light receiving means is used to obtain a blood sample from the difference between the blood oxygen concentration at a site where the oxygen partial pressure of the blood vessel is high and the blood oxygen concentration at a site where the oxygen partial pressure of the blood vessel is low based on the signal of each light receiving means. Without the above, a diabetes diagnostic device that accurately diagnoses whether or not the patient has diabetes and displays the diagnosis result on display means.

【0006】請求項2に記載した発明は、血管の酸素分
圧が高い部位として指を選択し、血管の酸素分圧の低い
部位として耳を選択するようにして、測定精度の高い、
また測定が容易に出来る糖尿病診断器としている。
According to a second aspect of the present invention, a finger is selected as a portion of a blood vessel having a high oxygen partial pressure, and an ear is selected as a portion of a blood vessel having a low oxygen partial pressure.
Also, it is a diabetes diagnostic device that can be easily measured.

【0007】請求項3に記載した発明は、第1の発光手
段と第2の発光手段とは、680nmと830nmの2
つの波長を発光するようにして、半導体レーザを使用で
き小型化した糖尿病診断器としている。
According to a third aspect of the present invention, the first light-emitting means and the second light-emitting means have two wavelengths of 680 nm and 830 nm.
A diabetic diagnostic device that emits light of two wavelengths and can be used with a semiconductor laser and is downsized.

【0008】請求項4に記載した発明は、制御手段は、
断食状態を継続している状態での診断結果を表示手段に
表示するようにして、精度の高い診断が出来る糖尿病診
断器の使用方法としている。
According to a fourth aspect of the present invention, the control means includes:
A diagnosis result in a state where the fasting state is continued is displayed on the display means, so that a method of using a diabetes diagnostic device capable of performing highly accurate diagnosis is provided.

【0009】[0009]

【実施例】以下本発明の実施例について説明する。図1
は本実施例の構成を示すブロック図である。1は血管の
酸素分圧が高い部位である指に照射する光を放射する第
1の発光手段で、発光素子等で構成している。2は、前
記第1の発光手段1が発光する光の内、指を透過した光
を受光する第1の受光手段で、受光素子によって構成し
ている。前記第1の発光手段1と第1の受光手段2と
は、指先を挿入する第1のプローブ12内に配置してい
る。なお、酸素分圧の低い測定部位として、耳の他に頭
部の額の皮膚や足のかかや鼻の頭などがある。また、3
は血管の酸素分圧が低い部位である耳に照射する光を放
射する第2の発光手段で、4は第2の発光手段3が発光
する光の内耳を透過した光を受光する第2の受光手段で
ある。前記第2の発光手段3と第2の受光手段4とは、
耳を挿入する第2のプローブ13内に配置している。な
お本実施例では、第1の受光手段2と第2の受光手段4
とは指をあるいは耳を透過した第1の発光手段1の光を
あるいは第2の発光手段3の光を受光するようにしてい
るが、指であるいは耳で反射された第1の発光手段1の
光をあるいは第2の発光手段3の光を受光するようにし
ても支障はないものである。
Embodiments of the present invention will be described below. FIG.
FIG. 2 is a block diagram showing the configuration of the present embodiment. Reference numeral 1 denotes a first light emitting unit that emits light to irradiate a finger, which is a site of a blood vessel having a high oxygen partial pressure, and is constituted by a light emitting element or the like. Reference numeral 2 denotes a first light receiving unit that receives light transmitted through a finger among the light emitted by the first light emitting unit 1, and is constituted by a light receiving element. The first light emitting means 1 and the first light receiving means 2 are arranged in a first probe 12 into which a fingertip is inserted. The measurement site having a low oxygen partial pressure includes the skin of the forehead of the head, the heel of the foot, the head of the nose, and the like in addition to the ear. Also, 3
Is a second light emitting means for emitting light to irradiate the ear, which is a site where the oxygen partial pressure of the blood vessel is low, and 4 is a second light receiving means for receiving light emitted by the second light emitting means 3 and transmitted through the inner ear. It is a light receiving means. The second light emitting means 3 and the second light receiving means 4
It is arranged in the second probe 13 into which the ear is inserted. In this embodiment, the first light receiving means 2 and the second light receiving means 4
Means that the light of the first light emitting means 1 or the light of the second light emitting means 3 transmitted through the finger or the ear is received, but the first light emitting means 1 reflected by the finger or the ear is received. There is no problem even if the light of the second light emitting means 3 is received.

【0010】前記第1の受光手段2と第2の受光手段4
の信号は、制御手段11に伝達されている。制御手段1
1は、第1の受光素子2の信号から血中酸素濃度を演算
する第1の演算装置5と、第2の受光素子4の信号から
血中酸素濃度を演算する第2の演算装置6と、第1の演
算装置と第2の演算装置で得られる血中酸素濃度の差を
求める血中酸素濃度差演算手段7と、血中酸素濃度の差
と糖尿病の関連を記憶している記憶手段8と、血中酸素
濃度差演算手段7によって求めた値と記憶手段8が記憶
している値とを比較して糖尿病であるかどうかを判断す
る判断手段9とを備えている。また制御手段11には、
判断手段9の判断結果を表示する表示手段10を接続し
ている。
The first light receiving means 2 and the second light receiving means 4
Are transmitted to the control means 11. Control means 1
1 is a first arithmetic unit 5 for calculating the blood oxygen concentration from the signal of the first light receiving element 2, and a second arithmetic unit 6 for calculating the blood oxygen concentration from the signal of the second light receiving element 4. A blood oxygen concentration difference calculating means 7 for obtaining a difference in blood oxygen concentration obtained by the first and second arithmetic devices, and a storage means for storing the relationship between the blood oxygen concentration difference and diabetes. And a determination means 9 for comparing the value obtained by the blood oxygen concentration difference calculation means 7 with the value stored in the storage means 8 to determine whether or not the patient has diabetes. The control means 11 includes
A display means 10 for displaying the result of the judgment by the judgment means 9 is connected.

【0011】以下本実施例の動作について説明する。本
実施例では、記憶手段8は、図2に示すような血中酸素
濃度と血管の酸素分圧の関係をプログラムとして記憶し
ている。この関係は発明者らが行った実験に基づくもの
である。図2は、横軸には血管の酸素分圧を、縦軸には
血中酸素濃度を採っている。図中Aとして示している特
性は糖尿病患者のものであり、Bとして示している特性
は健常者のものである。糖尿病患者では酸素分圧の高い
指先等の血中酸素濃度は約98%であり、酸素分圧の低
い耳での血中酸素濃度は約82%となっている。健常者
のものは指先での血中酸素濃度は約97%、耳での血中
酸素濃度は約75%となっている。つまり、糖尿病患者
の静脈と動脈の血中酸素濃度の差である酸素乖離量Cは
16%であり、健常者の静脈と動脈の血中酸素濃度の差
である酸素乖離量Dは22%となっている。前記酸素乖
離量は、生体の筋肉組織等に供給する酸素量を示してい
る。糖尿病患者の酸素乖離量は健常者のものより少ない
ものである。図3は、発明者らが実験によって求めてい
る血中酸素濃度の差と、糖尿病との関係を示す特性図で
ある。すなわち、縦軸には血中酸素濃度の差を%で示し
たものを、横軸は判断基準を採っているものである。す
なわち、本実施例の判断手段9は、血中酸素濃度の差が
20%以上であれば健常者と、20%から18%であれ
ば糖尿病予備軍として、18%以下であれば糖尿病であ
ると判断している。制御手段11は、前記判断手段9の
判断結果を表示手段10に表示させている。使用者は、
表示手段10の表示を見ることによって、自分が糖尿病
であるかどうかを確認できるものである。
The operation of the embodiment will be described below. In the present embodiment, the storage unit 8 stores the relationship between the blood oxygen concentration and the oxygen partial pressure of the blood vessel as a program as shown in FIG. This relationship is based on experiments performed by the inventors. In FIG. 2, the horizontal axis represents the oxygen partial pressure of the blood vessel, and the vertical axis represents the blood oxygen concentration. The characteristic shown as A in the figure is for a diabetic patient, and the characteristic shown as B is for a healthy person. In a diabetic patient, the blood oxygen concentration at a fingertip or the like having a high oxygen partial pressure is about 98%, and the blood oxygen concentration at an ear having a low oxygen partial pressure is about 82%. In a healthy person, the blood oxygen concentration at the fingertip is about 97%, and the blood oxygen concentration at the ear is about 75%. That is, the amount of oxygen divergence C, which is the difference between the blood oxygen concentration of the vein and the artery of the diabetic patient, is 16%, and the amount of oxygen divergence D, which is the difference between the blood oxygen concentration of the vein and the artery of the healthy subject, is 22%. Has become. The oxygen divergence indicates the amount of oxygen supplied to muscle tissue or the like of a living body. The amount of oxygen divergence in diabetic patients is smaller than that in healthy subjects. FIG. 3 is a characteristic diagram showing the relationship between the difference in blood oxygen concentration obtained by experiments by the inventors and diabetes. In other words, the vertical axis indicates the difference in blood oxygen concentration in%, and the horizontal axis indicates the criterion. That is, the judging means 9 of the present embodiment is a healthy person if the difference in blood oxygen concentration is 20% or more, a diabetic reserve if 20% to 18%, and a diabetic if 18% or less. I judge. The control means 11 causes the display means 10 to display the result of the judgment by the judgment means 9. The user
By looking at the display on the display means 10, it is possible to confirm whether oneself has diabetes.

【0012】以上のように本実施例によれば、血管の酸
素分圧が高い部位に配置した第1の発光手段1と、血管
の酸素分圧が低い部位に設置した第2の発光手段3と、
第1の発光手段1が照射した光のうち人体を透過した透
過光あるいは人体に反射された反射光を受光する第1の
受光手段2と、第2の発光手段3が照射した光のうち人
体を透過した透過光あるいは人体に反射された反射光を
受光する第2の受光手段4と、前記第1の受光手段2と
第2の受光手段4の信号から糖尿病であるかどうかを診
断し、表示手段10に診断結果を表示する制御手段11
とを備えた構成として、採血の必要が無く、正確な診断
ができる糖尿病診断器を実現するものである。
As described above, according to the present embodiment, the first light emitting means 1 disposed at a portion of a blood vessel having a high oxygen partial pressure and the second light emitting means 3 disposed at a portion of a blood vessel having a low oxygen partial pressure. When,
The first light receiving means 2 receives the transmitted light transmitted through the human body or the reflected light reflected by the human body out of the light emitted by the first light emitting means 1, and the human body out of the light emitted by the second light emitting means 3 A second light receiving means 4 for receiving the transmitted light transmitted through or the reflected light reflected on the human body, and diagnosing whether or not the patient is diabetic based on signals from the first light receiving means 2 and the second light receiving means 4; Control means 11 for displaying a diagnosis result on display means 10
The present invention realizes a diabetes diagnostic device that does not require blood collection and can perform an accurate diagnosis.

【0013】また、血管の酸素分圧が高い部位として指
を選択し、血管の酸素分圧が低い部位として耳を選択す
るようにして、測定が容易に出来、また測定精度の高い
糖尿病診断器を実現するものである。
In addition, a finger is selected as a part of the blood vessel where the oxygen partial pressure is high, and an ear is selected as a part of the blood vessel where the oxygen partial pressure is low, so that the measurement can be easily performed and the measurement accuracy is high. Is realized.

【0014】また本実施例で使用している第1の発光手
段1と第2の発光手段3とは、それぞれ680nmと8
30nmの2つの波長の光を発光させるようにしたとき
には、第1の発光手段1と第2の発光手段3に半導体レ
ーザを使用することができ、小型化した糖尿病診断器を
実現できるものである。
The first light emitting means 1 and the second light emitting means 3 used in the present embodiment have a wavelength of 680 nm and a wavelength of 8 nm, respectively.
When light of two wavelengths of 30 nm is emitted, a semiconductor laser can be used for the first light emitting means 1 and the second light emitting means 3, and a miniaturized diabetes diagnostic device can be realized. .

【0015】またこのとき、使用者が前夜から断食状態
を継続している状態で、本実施例の糖尿病診断器を使用
するようにすれば、血中酸素濃度が安定している状態で
測定が出来、安定した測定が出来るものである。
At this time, if the user uses the diabetes diagnosing device of the present embodiment in a state of fasting from the previous night, measurement can be performed in a state where the blood oxygen concentration is stable. It is possible to perform stable measurement.

【0016】[0016]

【発明の効果】請求項1に記載した発明は、血管の酸素
分圧が高い部位に配置した第1の発光手段と、血管の酸
素分圧が低い部位に設置した第2の発光手段と、第1の
発光手段が照射した光のうち人体を透過した透過光ある
いは人体に反射された反射光を受光する第1の受光手段
と、第2の発光手段が照射した光のうち人体を透過した
透過光あるいは人体に反射された反射光を受光する第2
の受光手段と、前記第1の受光手段と第2の受光手段の
信号から糖尿病であるかどうかを診断し、表示手段に診
断結果を表示する制御手段とを備えた構成として、採血
を伴うことなく、糖尿病であるかどうかを正確に診断で
きる糖尿病診断器を実現するものである。
According to the first aspect of the present invention, there is provided a first light emitting means disposed at a portion of a blood vessel having a high oxygen partial pressure, a second light emitting means provided at a portion of the blood vessel having a low oxygen partial pressure, The first light receiving means for receiving the transmitted light transmitted through the human body or the reflected light reflected on the human body out of the light emitted by the first light emitting means, and the light transmitted by the second light emitting means which has passed through the human body Second to receive transmitted light or reflected light reflected on the human body
Blood sampling as a configuration comprising: a light receiving means, and control means for diagnosing whether or not the patient has diabetes based on signals from the first light receiving means and the second light receiving means, and displaying the diagnosis result on the display means. Instead, the present invention realizes a diabetes diagnostic device that can accurately diagnose whether or not the patient has diabetes.

【0017】請求項2に記載した発明は、血管の酸素分
圧が高い部位として指を選択し、血管の酸素分圧が低い
部位として耳を選択した構成として、測定精度の高い、
また測定が容易に出来る糖尿病診断器を実現するもので
ある。
According to a second aspect of the present invention, a finger is selected as a portion of a blood vessel having a high oxygen partial pressure, and an ear is selected as a portion of a blood vessel having a low oxygen partial pressure.
Further, the present invention realizes a diabetes diagnostic device that can easily measure.

【0018】請求項3に記載した発明は、第1の発光手
段と第2の発光手段とは、それぞれ680nmと830
nmの2つの波長を発光する構成として、半導体レーザ
を使用でき小型化した糖尿病診断器を実現するものであ
る。
According to a third aspect of the present invention, the first light emitting means and the second light emitting means are 680 nm and 830 nm, respectively.
As a configuration that emits two wavelengths of nm, a miniaturized diabetes diagnostic device that can use a semiconductor laser is realized.

【0019】請求項4に記載した発明は、制御手段が、
断食状態を継続している状態での診断結果を表示手段に
表示するようにして、精度の高い診断が出来る糖尿病診
断器を実現するものである。
According to a fourth aspect of the present invention, the control means includes:
By displaying a diagnosis result in a state where the fasting state is continued on a display means, it is possible to realize a diabetes diagnostic device capable of performing a highly accurate diagnosis.

【図面の簡単な説明】[Brief description of the drawings]

【図1】本発明の実施例である糖尿病診断器の構成を示
すブロック図
FIG. 1 is a block diagram showing a configuration of a diabetes diagnostic device according to an embodiment of the present invention.

【図2】同、健常者と糖尿病患者の血中酸素濃度と酸素
分圧の関係を示す特性図
FIG. 2 is a characteristic diagram showing the relationship between blood oxygen concentration and oxygen partial pressure in healthy subjects and diabetic patients.

【図3】同、判断手段が有している判断基準示す説明図FIG. 3 is an explanatory diagram showing a criterion of the determination means.

【符号の説明】[Explanation of symbols]

1 第1の発光手段 2 第1の受光手段 3 第2の発光手段 4 第2の受光手段 5 第1の演算手段 6 第2の演算手段 7 血中酸素濃度差演算手段 8 記憶手段 9 判断手段 10 表示手段 11 制御手段 DESCRIPTION OF SYMBOLS 1 1st light emitting means 2 1st light receiving means 3 2nd light emitting means 4 2nd light receiving means 5 1st calculating means 6 2nd calculating means 7 blood oxygen concentration difference calculating means 8 storage means 9 judgment means 10 display means 11 control means

Claims (4)

【特許請求の範囲】[Claims] 【請求項1】 血管の酸素分圧が高い部位に配置した第
1の発光手段と、血管の酸素分圧が低い部位に設置した
第2の発光手段と、第1の発光手段が照射した光のうち
人体を透過した透過光あるいは人体に反射された反射光
を受光する第1の受光手段と、第2の発光手段が照射し
た光のうち人体を透過した透過光あるいは人体に反射さ
れた反射光を受光する第2の受光手段と、前記第1の受
光手段と第2の受光手段の信号から糖尿病であるかどう
かを診断し、表示手段に診断結果を表示する制御手段と
を備えた糖尿病診断器。
1. A first light emitting means disposed at a portion of a blood vessel having a high oxygen partial pressure, a second light emitting means provided at a portion of a blood vessel having a low oxygen partial pressure, and light irradiated by the first light emitting means. A first light receiving means for receiving transmitted light transmitted through the human body or reflected light reflected by the human body, and a transmitted light transmitted through the human body or a reflected light reflected by the human body among the lights irradiated by the second light emitting means Diabetes comprising: a second light receiving means for receiving light; and a control means for diagnosing whether or not diabetes is present based on signals from the first light receiving means and the second light receiving means, and displaying a diagnosis result on a display means. Diagnostic device.
【請求項2】 血管の酸素分圧が高い部位として指を選
択し、血管の酸素分圧が低い部位として耳を選択した請
求項1に記載した糖尿病診断器。
2. The diabetes diagnostic device according to claim 1, wherein a finger is selected as a portion of the blood vessel having a high oxygen partial pressure, and an ear is selected as a portion of the blood vessel having a low oxygen partial pressure.
【請求項3】 第1の発光手段と第2の発光手段とは、
それぞれ680nmと830nmの2つの波長を発光す
る請求項1に記載した糖尿病診断器。
3. The first light emitting means and the second light emitting means,
The diabetes diagnostic device according to claim 1, which emits two wavelengths of 680 nm and 830 nm, respectively.
【請求項4】 制御手段は、断食状態を継続している状
態での診断結果を表示手段に表示する請求項1に記載し
た糖尿病診断器。
4. The diabetes diagnostic device according to claim 1, wherein the control means displays a diagnosis result in a state where the fasting state is continued on the display means.
JP10175559A 1998-06-23 1998-06-23 Diabetes diagnostic unit Pending JP2000005152A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP10175559A JP2000005152A (en) 1998-06-23 1998-06-23 Diabetes diagnostic unit

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP10175559A JP2000005152A (en) 1998-06-23 1998-06-23 Diabetes diagnostic unit

Publications (1)

Publication Number Publication Date
JP2000005152A true JP2000005152A (en) 2000-01-11

Family

ID=15998207

Family Applications (1)

Application Number Title Priority Date Filing Date
JP10175559A Pending JP2000005152A (en) 1998-06-23 1998-06-23 Diabetes diagnostic unit

Country Status (1)

Country Link
JP (1) JP2000005152A (en)

Similar Documents

Publication Publication Date Title
US6990426B2 (en) Diagnostic method and apparatus using light
US8133177B2 (en) System and method for assessing capillary vitality
US20090143655A1 (en) Apparatus, System and Method for Determining Cardio-Respiratory State
JP5234186B2 (en) Optical biometric device
JP2009089883A (en) Atrial fibrillation detector, system and method
US20080004513A1 (en) VCSEL Tissue Spectrometer
US20020115935A1 (en) Method and apparatus for the detection of medical conditions of shock and pre-shock
US20130324814A1 (en) Estimation of systemic vascular resistance and cardiac output using arterial pulse oximetry waveforms
JPWO2003068070A1 (en) Biological function diagnostic device
EA013620B1 (en) Mobile diagnosis device
JP2006158974A (en) Integral type physiologic signal evaluation apparatus
Mignani et al. In-vivo biomedical monitoring by fiber-optic systems
JP5447396B2 (en) Light measuring device
US20110245687A1 (en) Optical detection method and device for optical detection of the condition of joints
US11147461B2 (en) Blood pressure analyzing apparatus, blood pressure measuring apparatus, and blood pressure analyzing method
US20110184298A1 (en) Portable cardio waveform acquisiton and heart rate variability (hrv) analysis
JP4651186B2 (en) Biological light measurement device
KR20140031589A (en) Apparatus for determiningblood velocity using hall element pulse diagnosis wave and photoplethysmograph pulse diagnosis wave
KR101054515B1 (en) Cardiovascular Autonomic Nervous System for Diabetic Neuropathy
US11039795B2 (en) Physiological monitoring and related methods
KR20100114330A (en) Portable instrument for measurement and analysis of bio-signal including ecg and pcg at the same time
JP2008289678A (en) Vascular endothelium function measuring instrument
JP2000005152A (en) Diabetes diagnostic unit
US20210022593A1 (en) Photoplethysmography Imaging (PPGI)-Based Pulp Vitality Test
US20220142520A1 (en) A non-invasive glucometer

Legal Events

Date Code Title Description
A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20041025

RD01 Notification of change of attorney

Free format text: JAPANESE INTERMEDIATE CODE: A7421

Effective date: 20041112

RD01 Notification of change of attorney

Free format text: JAPANESE INTERMEDIATE CODE: A7421

Effective date: 20050627

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20060523

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20060530

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20061010