IN2014DN07531A - - Google Patents
Info
- Publication number
- IN2014DN07531A IN2014DN07531A IN7531DEN2014A IN2014DN07531A IN 2014DN07531 A IN2014DN07531 A IN 2014DN07531A IN 7531DEN2014 A IN7531DEN2014 A IN 7531DEN2014A IN 2014DN07531 A IN2014DN07531 A IN 2014DN07531A
- Authority
- IN
- India
- Prior art keywords
- biological sample
- composite image
- generating
- providing
- image
- Prior art date
Links
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/645—Specially adapted constructive features of fluorimeters
- G01N21/6456—Spatial resolved fluorescence measurements; Imaging
- G01N21/6458—Fluorescence microscopy
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57415—Specifically defined cancers of breast
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57423—Specifically defined cancers of lung
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/71—Assays involving receptors, cell surface antigens or cell surface determinants for growth factors; for growth regulators
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Pathology (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- General Physics & Mathematics (AREA)
- Microbiology (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Optics & Photonics (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Peptides Or Proteins (AREA)
Abstract
A method for providing a composite image of a single biological sample comprising the steps of generating a first image of the biological sample generating a second image of the biological sample and generating a composite image that provides the relative location of both the target protein and the target nucleic acid. Also provided is a method of analyzing a biological sample comprising providing a composite image of the biological sample according to the method for providing a composite image and analyzing the expression of the protein and the nucleic acid sequences of interest from the composite image. Further provided are system and kit that comprise the means for executing the novel methods.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261618132P | 2012-03-30 | 2012-03-30 | |
PCT/US2013/033249 WO2013148448A1 (en) | 2012-03-30 | 2013-03-21 | Immunoflu0rescence and fluorescent-based nucleic acid analysis on a single sample |
Publications (1)
Publication Number | Publication Date |
---|---|
IN2014DN07531A true IN2014DN07531A (en) | 2015-04-24 |
Family
ID=48050953
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IN7531DEN2014 IN2014DN07531A (en) | 2012-03-30 | 2013-03-21 |
Country Status (12)
Country | Link |
---|---|
US (1) | US20150065371A1 (en) |
EP (1) | EP2831591B1 (en) |
JP (1) | JP6225163B2 (en) |
KR (1) | KR20140142715A (en) |
CN (1) | CN104520713A (en) |
AU (1) | AU2013240127B2 (en) |
CA (1) | CA2867508C (en) |
IN (1) | IN2014DN07531A (en) |
NZ (1) | NZ630091A (en) |
RU (1) | RU2014137129A (en) |
SG (1) | SG11201406105UA (en) |
WO (1) | WO2013148448A1 (en) |
Families Citing this family (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104884605B (en) | 2012-08-24 | 2018-05-18 | 耶鲁大学 | For the systems, devices and methods of high-throughput multi detection |
US10088658B2 (en) | 2013-03-18 | 2018-10-02 | General Electric Company | Referencing in multi-acquisition slide imaging |
AU2015220783B2 (en) * | 2014-02-24 | 2021-02-04 | Ventana Medical Systems, Inc. | Methods, kits, and systems for scoring the immune response to cancer by simultaneous detection of CD3, CD8, CD20, and FoxP3 |
CN104980558B (en) * | 2014-04-01 | 2019-01-01 | 中国移动通信集团公司 | A kind of method, apparatus of information processing, mobile phone pet client and mobile terminal |
WO2015157246A2 (en) * | 2014-04-07 | 2015-10-15 | Massachusetts Institute Of Technology | Use of microparticle additives to simultaneously enable artifact-free image registration, auto-focusing, and chromatic aberration correction in microscopy |
CA2995719A1 (en) * | 2014-08-18 | 2016-02-25 | Viewsiq Inc. | System and method for embedded images in large field-of-view microscopic scans |
US10584366B2 (en) | 2014-12-03 | 2020-03-10 | IsoPlexis Corporation | Analysis and screening of cell secretion profiles |
US11353448B2 (en) | 2015-02-13 | 2022-06-07 | California Institute Of Technology | Methods and compositions for quantifying metabolites and proteins from single cells |
CN107847145B (en) * | 2015-07-20 | 2020-08-14 | 徐敏 | Photonic structures and chemometric pathological systems |
US10748283B2 (en) | 2015-12-24 | 2020-08-18 | Konica Minolta, Inc. | Image processing device and program |
CN107419001A (en) * | 2016-05-23 | 2017-12-01 | 益善生物技术股份有限公司 | BRCA1, PTEN gene unconventionality detection kit and detection method |
JP6231709B1 (en) * | 2016-05-31 | 2017-11-15 | シスメックス株式会社 | Fluorescence image analyzer and analysis method |
US10846848B2 (en) | 2016-06-10 | 2020-11-24 | Hoffman-La Roche Inc. | System for bright field image simulation |
CN106290878A (en) * | 2016-09-10 | 2017-01-04 | 天津大学 | The preparation method of pancreatic tumour mark CA242 immuno-chromatographic test paper strip based on quantum dot |
JP7091348B2 (en) * | 2016-09-26 | 2022-06-27 | ベクトン・ディキンソン・アンド・カンパニー | Measurement of protein expression using reagents with barcoded oligonucleotide sequences |
EP3538891B1 (en) | 2016-11-11 | 2022-01-05 | Isoplexis Corporation | Compositions and methods for the simultaneous genomic, transcriptomic and proteomic analysis of single cells |
WO2018098372A1 (en) | 2016-11-22 | 2018-05-31 | IsoPlexis Corporation | Systems, devices and methods for cell capture and methods of manufacture thereof |
WO2020039520A1 (en) * | 2018-08-22 | 2020-02-27 | オリンパス株式会社 | Image processing device, image system, operation method of image processing device, and operation program of image processing device |
US10921223B2 (en) * | 2018-10-12 | 2021-02-16 | Shenzhen Prs Limited | Process record slide for staining and method of using the same |
CN110498858B (en) * | 2019-07-26 | 2024-01-23 | 深圳市达科为生物工程有限公司 | Method for dynamically detecting secretion condition of single-cell exoprotein |
US11783916B2 (en) * | 2019-12-17 | 2023-10-10 | Applied Materials, Inc. | System and method for acquisition and processing of multiplexed fluorescence in-situ hybridization images |
US20220018778A1 (en) * | 2020-07-20 | 2022-01-20 | Akoya Biosciences, Inc. | Processing and imaging tissue samples |
CN112415198B (en) * | 2020-11-20 | 2022-11-11 | 四川大学华西医院 | Application of GP1BB detection reagent in preparation of lung cancer screening kit |
CN113310963B (en) * | 2021-05-31 | 2023-12-01 | 四川大学华西医院 | Improved neutrophil NETs immunofluorescence detection method |
WO2023091909A1 (en) | 2021-11-16 | 2023-05-25 | Sotio Biotech Inc. | Treatment of myxoid/round cell liposarcoma patients |
WO2023147139A1 (en) * | 2022-01-28 | 2023-08-03 | University Of Southern California | Identifying non-disease patients using a disease related assay and analysis in the liquid biopsy |
WO2023147133A1 (en) * | 2022-01-28 | 2023-08-03 | University Of Southern California | Liquid biopsy analytes to define cancer stages |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6404906B2 (en) | 1997-03-03 | 2002-06-11 | Bacus Research Laboratories,Inc. | Method and apparatus for acquiring and reconstructing magnified specimen images from a computer-controlled microscope |
US6993169B2 (en) * | 2001-01-11 | 2006-01-31 | Trestle Corporation | System and method for finding regions of interest for microscopic digital montage imaging |
US7629125B2 (en) * | 2006-11-16 | 2009-12-08 | General Electric Company | Sequential analysis of biological samples |
US20110189670A1 (en) * | 2008-07-07 | 2011-08-04 | Ruth L Katz | Circulating Tumor and Tumor Stem Cell Detection Using Genomic Specific Probes |
US8269827B2 (en) * | 2009-09-29 | 2012-09-18 | General Electric Company | System and methods for mapping fluorescent images into a bright field color space |
-
2013
- 2013-03-21 SG SG11201406105UA patent/SG11201406105UA/en unknown
- 2013-03-21 JP JP2015503378A patent/JP6225163B2/en active Active
- 2013-03-21 KR KR20147027562A patent/KR20140142715A/en not_active Application Discontinuation
- 2013-03-21 US US14/387,861 patent/US20150065371A1/en active Pending
- 2013-03-21 EP EP13715086.8A patent/EP2831591B1/en active Active
- 2013-03-21 WO PCT/US2013/033249 patent/WO2013148448A1/en active Application Filing
- 2013-03-21 CN CN201380017702.4A patent/CN104520713A/en active Pending
- 2013-03-21 CA CA2867508A patent/CA2867508C/en active Active
- 2013-03-21 NZ NZ630091A patent/NZ630091A/en not_active IP Right Cessation
- 2013-03-21 AU AU2013240127A patent/AU2013240127B2/en active Active
- 2013-03-21 IN IN7531DEN2014 patent/IN2014DN07531A/en unknown
- 2013-03-21 RU RU2014137129A patent/RU2014137129A/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
US20150065371A1 (en) | 2015-03-05 |
JP2015514212A (en) | 2015-05-18 |
EP2831591B1 (en) | 2019-05-08 |
CA2867508A1 (en) | 2013-10-03 |
CN104520713A (en) | 2015-04-15 |
RU2014137129A (en) | 2016-05-27 |
JP6225163B2 (en) | 2017-11-01 |
AU2013240127B2 (en) | 2018-07-12 |
KR20140142715A (en) | 2014-12-12 |
SG11201406105UA (en) | 2014-10-30 |
EP2831591A1 (en) | 2015-02-04 |
CA2867508C (en) | 2021-05-18 |
NZ630091A (en) | 2016-03-31 |
AU2013240127A1 (en) | 2014-10-02 |
WO2013148448A1 (en) | 2013-10-03 |
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