IL163691A0 - 5-Pphenylthiazole derivatives and use as pi3 kinase - Google Patents
5-Pphenylthiazole derivatives and use as pi3 kinaseInfo
- Publication number
- IL163691A0 IL163691A0 IL16369103A IL16369103A IL163691A0 IL 163691 A0 IL163691 A0 IL 163691A0 IL 16369103 A IL16369103 A IL 16369103A IL 16369103 A IL16369103 A IL 16369103A IL 163691 A0 IL163691 A0 IL 163691A0
- Authority
- IL
- Israel
- Prior art keywords
- pphenylthiazole
- kinase
- derivatives
- pphenylthiazole derivatives
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/44—Acylated amino or imino radicals
- C07D277/46—Acylated amino or imino radicals by carboxylic acids, or sulfur or nitrogen analogues thereof
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/40—Unsubstituted amino or imino radicals
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- A—HUMAN NECESSITIES
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- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/44—Acylated amino or imino radicals
- C07D277/48—Acylated amino or imino radicals by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof, e.g. carbonylguanidines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB0204765A GB0204765D0 (en) | 2002-02-28 | 2002-02-28 | Organic compounds |
GB0229626A GB0229626D0 (en) | 2002-12-19 | 2002-12-19 | Organic compounds |
PCT/EP2003/002036 WO2003072557A1 (en) | 2002-02-28 | 2003-02-27 | 5-phenylthiazole derivatives and use as pi3 kinase inhibitors |
Publications (1)
Publication Number | Publication Date |
---|---|
IL163691A0 true IL163691A0 (en) | 2005-12-18 |
Family
ID=27767104
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL16369103A IL163691A0 (en) | 2002-02-28 | 2003-02-27 | 5-Pphenylthiazole derivatives and use as pi3 kinase |
IL163691A IL163691A (en) | 2002-02-28 | 2004-08-23 | 5-phenylthiazole derivatives, process for their preparation, compositions comprising them and use thereof in the preparation of medicaments for the treatment of diseases mediated by pi3 kinase |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL163691A IL163691A (en) | 2002-02-28 | 2004-08-23 | 5-phenylthiazole derivatives, process for their preparation, compositions comprising them and use thereof in the preparation of medicaments for the treatment of diseases mediated by pi3 kinase |
Country Status (28)
Country | Link |
---|---|
US (2) | US7687637B2 (en) |
EP (1) | EP1480962B1 (en) |
JP (2) | JP4408701B2 (en) |
KR (1) | KR100688370B1 (en) |
CN (1) | CN100548996C (en) |
AR (1) | AR038703A1 (en) |
AT (1) | ATE521598T1 (en) |
AU (1) | AU2003214080A1 (en) |
BR (1) | BR0308030A (en) |
CA (1) | CA2477601C (en) |
CO (1) | CO5611131A2 (en) |
CY (2) | CY1112084T1 (en) |
DK (2) | DK1480962T3 (en) |
EC (2) | ECSP045253A (en) |
ES (2) | ES2405816T3 (en) |
HK (1) | HK1071363A1 (en) |
IL (2) | IL163691A0 (en) |
MX (1) | MXPA04008362A (en) |
MY (1) | MY156407A (en) |
NO (1) | NO329175B1 (en) |
NZ (1) | NZ534657A (en) |
PE (1) | PE20030968A1 (en) |
PL (2) | PL215581B1 (en) |
PT (2) | PT2311818E (en) |
RU (2) | RU2436780C2 (en) |
SI (1) | SI1480962T1 (en) |
TW (1) | TWI314928B (en) |
WO (1) | WO2003072557A1 (en) |
Families Citing this family (83)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU770896C (en) | 1998-09-29 | 2006-09-07 | Gamida Cell Ltd. | Methods of controlling proliferation and differentiation of stem and progenitor cells |
IL152904A0 (en) | 2002-01-24 | 2003-06-24 | Gamida Cell Ltd | Utilization of retinoid and vitamin d receptor antagonists for expansion of renewable stem cell populations |
WO2003062404A1 (en) | 2002-01-25 | 2003-07-31 | Gamida-Cell Ltd. | Methods of expanding stem and progenitor cells and expanded cell populations obtained thereby |
WO2004072068A1 (en) | 2003-02-10 | 2004-08-26 | Amgen Inc. | Vanilloid receptor ligands and their use in treatments |
GB0305152D0 (en) | 2003-03-06 | 2003-04-09 | Novartis Ag | Organic compounds |
WO2004087138A1 (en) * | 2003-03-31 | 2004-10-14 | Sucampo Ag | Method for treating vascular hyperpermeable disease |
TW200519106A (en) | 2003-05-02 | 2005-06-16 | Novartis Ag | Organic compounds |
GB0320197D0 (en) * | 2003-08-28 | 2003-10-01 | Novartis Ag | Organic compounds |
ZA200605624B (en) * | 2004-01-12 | 2007-11-28 | Applied Research Systems | Thiazole derivatives and use thereof |
ES2442678T3 (en) | 2004-08-28 | 2014-02-12 | Astrazeneca Ab | Pyrimidine sulfonamide derivatives as chemokine receptor modulators |
MX2007004051A (en) | 2004-10-07 | 2007-05-24 | Boehringer Ingelheim Int | Pi3 kinases. |
UY29149A1 (en) * | 2004-10-07 | 2006-05-31 | Boehringer Ingelheim Int | TIAZOLIL-DIHIDRO-INDAZOLES |
SE0402735D0 (en) * | 2004-11-09 | 2004-11-09 | Astrazeneca Ab | Novel compounds |
EP3530290A1 (en) * | 2005-05-05 | 2019-08-28 | GlaxoSmithKline Intellectual Property Development Limited | Alpha aminoacid ester-drug conjugates hydrolysable by carboxylesterase |
BRPI0611029A2 (en) | 2005-05-24 | 2010-08-10 | Serono Lab | thiazole derivatives and their use |
BRPI0610341A2 (en) * | 2005-05-24 | 2010-06-15 | Serono Lab | thiazole derivatives and their use |
US8846393B2 (en) | 2005-11-29 | 2014-09-30 | Gamida-Cell Ltd. | Methods of improving stem cell homing and engraftment |
EP1968597A4 (en) * | 2005-12-01 | 2012-01-11 | Scripps Research Inst | Compositions and methods for inducing neuronal differentiation |
GB0525671D0 (en) * | 2005-12-16 | 2006-01-25 | Novartis Ag | Organic compounds |
CA2636077C (en) * | 2006-01-18 | 2012-01-03 | Amgen Inc. | Thiazole compounds as protein kinase b (pkb) inhibitors |
WO2007098826A2 (en) * | 2006-01-18 | 2007-09-07 | Siena Biotech S.P.A. | Modulators of alpha7 nicotinic acetylcholine receptors and therapeutic uses thereof |
JP2009523769A (en) * | 2006-01-23 | 2009-06-25 | ラボラトワール セローノ ソシエテ アノニム | Thiazole derivatives and their use |
US7517995B2 (en) | 2006-04-06 | 2009-04-14 | Boehringer Ingelheim International Gmbh | Thiazolyl-dihydro-cyclopentapyrazole |
US7691868B2 (en) | 2006-04-06 | 2010-04-06 | Boehringer Ingelheim International Gmbh | Thiazolyl-dihydro-quinazoline |
US20070238746A1 (en) * | 2006-04-06 | 2007-10-11 | Trixi Brandl | Thiazolyl-dihydro-chinazoline |
CN101484452A (en) * | 2006-05-03 | 2009-07-15 | 阿斯利康(瑞典)有限公司 | Thiazole derivatives and their use as anti-tumour agents |
GB0608823D0 (en) * | 2006-05-04 | 2006-06-14 | Chroma Therapeutics Ltd | Inhibitors of P13 kinase |
GB0608854D0 (en) * | 2006-05-04 | 2006-06-14 | Chroma Therapeutics Ltd | P13 kinase inhibitors |
GB0610243D0 (en) | 2006-05-23 | 2006-07-05 | Novartis Ag | Organic compounds |
GB0612630D0 (en) * | 2006-06-26 | 2006-08-02 | Novartis Ag | Organic compounds |
DK1887359T3 (en) * | 2006-08-03 | 2009-03-02 | Cellzome Ag | Method for identifying PI3K interacting molecules and for purifying PI3K |
JP2010502628A (en) * | 2006-09-01 | 2010-01-28 | バーテックス ファーマシューティカルズ インコーポレイテッド | 5- (2-Furyl) -1,3-thiazole derivatives useful as inhibitors of phosphatidylinositol 3-kinase |
ES2421326T3 (en) * | 2006-11-29 | 2013-08-30 | Abbvie Inc. | Diacylglycerol O-acyltransferase type 1 enzyme inhibitors |
PE20090717A1 (en) * | 2007-05-18 | 2009-07-18 | Smithkline Beecham Corp | QUINOLINE DERIVATIVES AS PI3 KINASE INHIBITORS |
EP2581081A3 (en) | 2007-06-01 | 2013-07-31 | The Trustees Of Princeton University | Treatment of viral infections by modulation of host cell metabolic pathways |
WO2009011871A2 (en) * | 2007-07-17 | 2009-01-22 | Amgen Inc. | Thiadiazole modulators of pkb |
CA2692713A1 (en) | 2007-07-17 | 2009-01-22 | Amgen Inc. | Heterocyclic modulators of pkb |
JP2011506560A (en) | 2007-12-20 | 2011-03-03 | ノバルティス アーゲー | Thiazole derivatives used as PI3 kinase inhibitors |
AU2009211845A1 (en) | 2008-02-04 | 2009-08-13 | Cellzome Gmbh | Selectivity profiling of PI3K interacting molecules against multiple targets |
UA104147C2 (en) | 2008-09-10 | 2014-01-10 | Новартис Аг | Pyrrolidine dicarboxylic acid derivative and use thereof in the treatment of proliferative diseases |
CN101684106B (en) * | 2008-09-22 | 2013-06-12 | 北京摩力克科技有限公司 | Thiazole onium salt compound and application for treating diseases relative to protein aging thereof |
CN102333765B (en) * | 2009-02-27 | 2015-01-14 | 帝人制药株式会社 | Process for producing phenyl-substituted heterocyclic derivative through coupling using transition metal catalyst |
TW201103943A (en) * | 2009-04-27 | 2011-02-01 | Shionogi & Co | Urea derivative having pi3k inhibitory activity |
US8293753B2 (en) | 2009-07-02 | 2012-10-23 | Novartis Ag | Substituted 2-carboxamide cycloamino ureas |
MX2012000178A (en) | 2009-07-02 | 2012-02-28 | Novartis Ag | 2-carboxamide cycloamino ureas useful as pi3k inhibitors. |
GB0913345D0 (en) | 2009-07-31 | 2009-09-16 | Astrazeneca Ab | New combination 802 |
JPWO2011048936A1 (en) | 2009-10-19 | 2013-03-07 | 大正製薬株式会社 | Aminothiazole derivatives |
WO2011061527A1 (en) | 2009-11-17 | 2011-05-26 | Astrazeneca Ab | Combinations comprising a glucocorticoid receptor modulator for the treatment of respiratory diseases |
CA2788678C (en) | 2010-02-03 | 2019-02-26 | Signal Pharmaceuticals, Llc | Identification of lkb1 mutation as a predictive biomarker for sensitivity to tor kinase inhibitors |
WO2012071480A2 (en) * | 2010-11-24 | 2012-05-31 | Lithera, Inc. | Lipophilic glucocorticosteroid monotherapeutic formulations and methods for the cosmetic treatment of adiposity and contour bulging |
GB201021992D0 (en) | 2010-12-23 | 2011-02-02 | Astrazeneca Ab | Compound |
GB201021979D0 (en) | 2010-12-23 | 2011-02-02 | Astrazeneca Ab | New compound |
EP2739751A1 (en) | 2011-08-03 | 2014-06-11 | Signal Pharmaceuticals, LLC | Identification of gene expression profile as a predictive biomarker for lkb1 status |
US9926309B2 (en) | 2011-10-05 | 2018-03-27 | The Board Of Trustees Of The Leland Stanford Junior University | Pi-kinase inhibitors with anti-infective activity |
WO2013052845A1 (en) | 2011-10-05 | 2013-04-11 | The Board Of Trustees Of The Leland Stanford Junior University | Pi-kinase inhibitors with broad spectrum anti-infective activity |
SG11201404608WA (en) | 2012-02-13 | 2014-09-26 | Gamida Cell Ltd | Mesenchymal stem cells conditioned medium and methods of generating and using the same |
US9567569B2 (en) | 2012-07-23 | 2017-02-14 | Gamida Cell Ltd. | Methods of culturing and expanding mesenchymal stem cells |
US9175266B2 (en) | 2012-07-23 | 2015-11-03 | Gamida Cell Ltd. | Enhancement of natural killer (NK) cell proliferation and activity |
AU2013203714B2 (en) | 2012-10-18 | 2015-12-03 | Signal Pharmaceuticals, Llc | Inhibition of phosphorylation of PRAS40, GSK3-beta or P70S6K1 as a marker for TOR kinase inhibitory activity |
EA030726B1 (en) | 2013-04-17 | 2018-09-28 | СИГНАЛ ФАРМАСЬЮТИКАЛЗ, ЭлЭлСи | PHARMACEUTICAL FORMULATIONS, PROCESSES, SOLID FORMS AND METHODS OF USE RELATING TO 1-ETHYL-7-(2-METHYL-6-(1H-1,2,4-TRIAZOL-3-YL)PYRIDIN-3-YL)-3,4-DIHYDROPYRAZINO[2,3-b]PYRAZIN-2(1H)-ONE |
MX2015014590A (en) | 2013-04-17 | 2016-03-03 | Signal Pharm Llc | Treatment of cancer with dihydropyrazino-pyrazines. |
CN105339008A (en) | 2013-04-17 | 2016-02-17 | 西格诺药品有限公司 | Combination therapy comprising tor kinase inhibitor and n-(3-(5-fluoro-2-(4-(2-methoxyethoxy)phenylamino)pyrimidin-4-ylamino)phenyl)acrylamide for treating cancer |
US9937169B2 (en) | 2013-04-17 | 2018-04-10 | Signal Pharmaceuticals, Llc | Methods for treating cancer using dihydropyrazino-pyrazine compound combination therapy |
CA2908742C (en) | 2013-04-17 | 2021-06-01 | Signal Pharmaceuticals, Llc | Combination therapy comprising a tor kinase inhibitor and a cytidine analog for treating cancer |
CA2909625C (en) | 2013-04-17 | 2021-06-01 | Signal Pharmaceuticals, Llc | Combination therapy comprising a tor kinase inhibitor and a 5-substituted quinazolinone compound for treating cancer |
EA030808B1 (en) | 2013-04-17 | 2018-09-28 | СИГНАЛ ФАРМАСЬЮТИКАЛЗ, ЭлЭлСи | USE OF 1-ETHYL-7-(2-METHYL-6-(1H-1,2,4-TRIAZOL-3-YL)PYRIDIN-3-YL)-3,4-DIHYDROPYRAZINO[2,3-b]PYRAZIN-2(1H)-ONE IN THE TREATMENT OF GLIOBLASTOMA MULTIFORME |
MX2015015880A (en) | 2013-05-29 | 2016-05-31 | Signal Pharm Llc | PHARMACEUTICAL COMPOSITIONS OF 7-(6-(2-HYDROXYPROPAN-2-YL)PYRIDIN -3-YL)-1-((TRANS)-4-METHOXYCYCLOHEXYL)-3,4-DIHYDROPYRAZINO[2,3-< i>B]PYRAZIN-2(1H)-ONE, A SOLID FORM THEREOF AND METHODS OF THEIR USE. |
CN104418858B (en) | 2013-08-30 | 2018-12-11 | 浙江医药股份有限公司新昌制药厂 | Nitrogenous substituted purine derivative of 2,6- bis- and preparation method thereof and its pharmaceutical composition and application |
DE102013226711A1 (en) * | 2013-12-19 | 2015-06-25 | Beiersdorf Ag | Use of alkylamidothiazoles in cosmetic or dermatological preparations for the prophylaxis and treatment of sensitive skin |
NZ714742A (en) | 2014-04-16 | 2017-04-28 | Signal Pharm Llc | Solid forms of 1-ethyl-7-(2-methyl-6-(1h-1,2,4-triazol-3-yl)pyridin-3-yl)-3,4-dihydropyrazino[2,3-b]pyrazin-2(1h)-one, compositions thereof and methods of their use |
WO2015160880A1 (en) | 2014-04-16 | 2015-10-22 | Signal Pharmaceuticals, Llc | SOLID FORMS COMPRISING 1-ETHYL-7-(2-METHYL-6-(1H-1,2,4-TRIAZOL-3-YL) PYRIDIN-3-YL)-3,4-DIHYDROPYRAZINO(2,3-b)PYRAZIN-2(1H)-ONE, AND A COFORMER, COMPOSITIONS AND METHODS OF USE THEREOF |
WO2015162584A1 (en) | 2014-04-24 | 2015-10-29 | Novartis Ag | Crystalline forms of the sulfate salt of n-[5-(3-imidazol-1-yl-4-methanesulfonyl-phenyl)-4-methyl-thiazol-2-yl]-acetamide |
WO2016065583A1 (en) | 2014-10-30 | 2016-05-06 | Merck Sharp & Dohme Corp. | Oxazole orexin receptor antagonists |
MX2018002331A (en) * | 2015-09-04 | 2018-07-06 | Dow Agrosciences Llc | Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto. |
MX2018002337A (en) * | 2015-09-04 | 2018-07-06 | Dow Agrosciences Llc | Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto. |
CN108349881B (en) * | 2015-09-10 | 2020-11-27 | 美国陶氏益农公司 | Molecules having pesticidal utility, and intermediates, compositions and methods related thereto |
PT3395801T (en) * | 2015-12-16 | 2021-05-24 | Nippon Soda Co | Arylazole compound and pest control agent |
US10808017B2 (en) | 2016-02-01 | 2020-10-20 | The Governing Council Of The University Of Toronto | Ubiquitin variants and uses therof as 53BP1 inhibitors |
EP3419980A4 (en) | 2016-02-26 | 2019-07-03 | The Board of Trustees of the Leland Stanford Junior University | Pi-kinase inhibitors with anti-infective activity |
CN110996955A (en) | 2017-06-22 | 2020-04-10 | 细胞基因公司 | Treatment of hepatocellular carcinoma characterized by hepatitis B virus infection |
EP3713963A1 (en) * | 2017-11-23 | 2020-09-30 | INSERM (Institut National de la Santé et de la Recherche Médicale) | A new marker for predicting the sensitivity to pi3k inhibitors |
BR112021018724A8 (en) * | 2019-03-21 | 2021-11-23 | Univ Leland Stanford Junior | "pi4-kinase inhibitors and methods of using the same |
CN115028596A (en) * | 2021-03-03 | 2022-09-09 | 帕潘纳(北京)科技有限公司 | Process for preparing topramezone intermediates |
Family Cites Families (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB951885A (en) * | 1961-05-13 | 1964-03-11 | Sankyo Co | A new process for the preparation of thiazole compounds |
OA01933A (en) | 1965-04-06 | 1970-02-04 | Pechiney Saint Gobain | Thiazole derivatives. |
US3749775A (en) * | 1969-07-07 | 1973-07-31 | Stauffer Chemical Co | Insecticidal 2-aminothiazole phosphates and phosphonates |
FR2429210A1 (en) | 1978-06-19 | 1980-01-18 | Fabre Sa Pierre | PHENYL-4 THIAZOLYL-2 OXAMATE DERIVATIVES USEFUL IN THE TREATMENT OF ASTHMA |
JPS57136579A (en) | 1981-01-21 | 1982-08-23 | Mitsui Toatsu Chem Inc | Thiazolylurea derivative, its preparation, and pharmaceutical composition containing the same |
EP0068033B1 (en) | 1981-01-08 | 1985-07-10 | Mitsui Toatsu Kagaku Kabushiki Kaisha | N-(4-phenyl-2-thiazolyl)carbamate derivatives, process for their preparation, and medicinal composition containing same |
DE3413755A1 (en) | 1984-04-12 | 1985-10-24 | Basf Ag, 6700 Ludwigshafen | THIAZOLYL UREAS, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE FOR COMBATING UNWANTED PLANT GROWTH |
JPH0725754B2 (en) * | 1986-01-30 | 1995-03-22 | 富山化学工業株式会社 | Novel thiazole compound or salt thereof |
EP0321115B1 (en) | 1987-12-14 | 1991-08-14 | Sawai Pharmaceutical Co., Ltd. | Carboxamide derivatives having tetrazole and thiazole rings and their use |
US4891375A (en) | 1988-01-13 | 1990-01-02 | Pfizer Inc. | Arylpiperazinyl-alkylene-phenyl-heterocyclic compounds |
CA2396738C (en) | 1990-11-30 | 2006-08-29 | Masatoshi Chihiro | Thiazole derivatives as active superoxide radical inhibitors |
DE4401911A1 (en) * | 1994-01-24 | 1995-08-03 | Basf Ag | Use of aryl or heteroarylazoanilines in non-linear optics |
EP1125932A3 (en) | 1994-07-27 | 2001-08-29 | G.D. Searle & Co. | Substituted thiazoles for the treatment of inflammation |
EP0790057B1 (en) * | 1994-11-29 | 2002-06-05 | Hisamitsu Pharmaceutical Co., Inc. | Antibacterial or bactericide comprising 2-aminothiazole derivative and salts thereof |
GB9625843D0 (en) | 1996-12-12 | 1997-01-29 | Merck & Co Inc | Phenyl spiroethercycloalkyl tachykinn receptor antagonists |
CZ299156B6 (en) | 1997-12-22 | 2008-05-07 | Bayer Corporation | Substituted heterocyclic ureas, pharmaceutical compositions in which they are comprised and their use |
US6100282A (en) * | 1998-01-02 | 2000-08-08 | Hoffman-La Roche Inc. | Thiazole derivatives |
SI0928790T1 (en) * | 1998-01-02 | 2003-06-30 | F. Hoffmann-La Roche Ag | Thiazole derivatives |
US6043254A (en) | 1998-04-03 | 2000-03-28 | Boehringer Ingelheim Pharma Kg | Indolinones having kinase-inhibiting activity |
GB9823873D0 (en) * | 1998-10-30 | 1998-12-30 | Pharmacia & Upjohn Spa | 2-ureido-thiazole derivatives,process for their preparation,and their use as antitumour agents |
ATE363471T1 (en) | 2000-01-24 | 2007-06-15 | Astrazeneca Ab | THERAPEUTIC COMPOUNDS SUBSTITUTED BY A MORPHOLINE RESIDUE |
WO2001081346A2 (en) | 2000-04-25 | 2001-11-01 | Icos Corporation | Inhibitors of human phosphatidyl-inositol 3-kinase delta |
CN100457753C (en) | 2000-07-26 | 2009-02-04 | 布里斯托尔-迈尔斯斯奎布公司 | N-[5-[[[5-alkyl-2-oxazolyl]methyl]thio]-2-thiazolyl] carboxamide inhibitors of cyclin dependent kinases |
ATE553758T1 (en) | 2000-12-18 | 2012-05-15 | Inst Med Molecular Design Inc | INHIBITORS FOR THE PRODUCTION AND RELEASE OF INFLAMMATORY CYTOKINE |
AR039059A1 (en) | 2001-08-06 | 2005-02-09 | Sanofi Aventis | COMPOUND DERIVED FROM ACILAMINOTIAZOL, ITS USE, PROCEDURES TO PREPARE IT, PHARMACEUTICAL COMPOSITION THAT INCLUDES IT, AND INTERMEDIARY COMPOUNDS |
AU2002327534A1 (en) * | 2001-08-17 | 2003-03-03 | Merck And Co., Inc. | Tyrosine kinase inhibitors |
US6812653B2 (en) * | 2002-07-26 | 2004-11-02 | Richard S. Bellivean | Method and apparatus for controlling images with image projection lighting devices |
GB0525671D0 (en) * | 2005-12-16 | 2006-01-25 | Novartis Ag | Organic compounds |
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