HU905459D0 - Adjuvant preparation containing submicronal oil-drop emulsion - Google Patents
Adjuvant preparation containing submicronal oil-drop emulsionInfo
- Publication number
- HU905459D0 HU905459D0 HU905459A HU545990A HU905459D0 HU 905459 D0 HU905459 D0 HU 905459D0 HU 905459 A HU905459 A HU 905459A HU 545990 A HU545990 A HU 545990A HU 905459 D0 HU905459 D0 HU 905459D0
- Authority
- HU
- Hungary
- Prior art keywords
- oil
- submicronal
- preparation containing
- adjuvant preparation
- drop emulsion
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
- A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers with substantial amounts of non-phosphatidyl, i.e. non-acylglycerophosphate, surfactants as bilayer-forming substances, e.g. cationic lipids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/70—Nanostructure
- Y10S977/788—Of specified organic or carbon-based composition
- Y10S977/802—Virus-based particle
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/902—Specified use of nanostructure
- Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
- Y10S977/918—Immunological
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Dispersion Chemistry (AREA)
- Biophysics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Cosmetics (AREA)
- Colloid Chemistry (AREA)
- Detergent Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US35703589A | 1989-05-25 | 1989-05-25 |
Publications (3)
Publication Number | Publication Date |
---|---|
HU905459D0 true HU905459D0 (en) | 1992-02-28 |
HUT61203A HUT61203A (en) | 1992-12-28 |
HU212924B HU212924B (en) | 1996-12-30 |
Family
ID=23404033
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU905459A HU212924B (en) | 1989-05-25 | 1990-05-24 | Adjuvant formulation comprising a submicron oil droplet emulsion |
Country Status (15)
Country | Link |
---|---|
US (3) | US6299884B1 (en) |
EP (1) | EP0399843B1 (en) |
JP (1) | JPH0832638B2 (en) |
AT (1) | ATE108327T1 (en) |
CA (1) | CA2017507C (en) |
DD (1) | DD294633A5 (en) |
DE (2) | DE399843T1 (en) |
DK (1) | DK0399843T5 (en) |
ES (1) | ES2033626T3 (en) |
GR (1) | GR910300063T1 (en) |
HK (1) | HK107695A (en) |
HU (1) | HU212924B (en) |
IE (1) | IE64766B1 (en) |
PT (1) | PT94168B (en) |
WO (1) | WO1990014837A1 (en) |
Families Citing this family (637)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5364632A (en) * | 1989-04-05 | 1994-11-15 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Medicinal emulsions |
US5200344A (en) * | 1990-11-13 | 1993-04-06 | Blaser Martin J | Diagnostic testing for campylobacter jejuni or campylobacter coli infections using novel antigens |
US6197311B1 (en) | 1991-07-25 | 2001-03-06 | Idec Pharmaceuticals Corporation | Induction of cytotoxic T-lymphocyte responses |
US5709860A (en) * | 1991-07-25 | 1998-01-20 | Idec Pharmaceuticals Corporation | Induction of cytotoxic T-lymphocyte responses |
US5585103A (en) * | 1991-07-25 | 1996-12-17 | Idec Pharmaceutical Corporation | Induction of cytotoxic T-lymphocyte responses |
CA2083553A1 (en) * | 1991-11-25 | 1993-05-26 | Kuniharu Seki | Immunogen composition |
EP1421951A3 (en) | 1993-05-12 | 2005-10-05 | Chiron Corporation | Conserved motif of hepatitis C virus E2/NS1 region |
DE4322826A1 (en) * | 1993-07-08 | 1995-01-12 | Galenik Labor Freiburg Gmbh | Pharmaceutical preparation |
JPH09502604A (en) * | 1993-08-27 | 1997-03-18 | エンテリック リサーチ ラボラトリーズ インコーポレイテッド | Campylobacter jejuni antigens, and their production and use |
US5919466A (en) * | 1993-10-01 | 1999-07-06 | Gerbu Biotechnik Gmbh | Method for improving the yield of immunoantibodies in the vaccination of animals and humans |
ATE223702T1 (en) * | 1993-10-22 | 2002-09-15 | Genentech Inc | METHOD AND COMPOSITIONS FOR MICROCAPSULATING ADJUVANTS |
US6913767B1 (en) | 1993-10-25 | 2005-07-05 | Genentech, Inc. | Compositions for microencapsulation of antigens for use as vaccines |
US5643605A (en) * | 1993-10-25 | 1997-07-01 | Genentech, Inc. | Methods and compositions for microencapsulation of adjuvants |
US5961970A (en) * | 1993-10-29 | 1999-10-05 | Pharmos Corporation | Submicron emulsions as vaccine adjuvants |
GB9326253D0 (en) * | 1993-12-23 | 1994-02-23 | Smithkline Beecham Biolog | Vaccines |
US5629167A (en) * | 1994-04-19 | 1997-05-13 | Biocine S.P.A. | Detection of antibodies against Chlamydia trachomatis pgp3 antigen in patient sera by enzyme-linked immunosorbent assay |
WO1996009757A1 (en) * | 1994-09-28 | 1996-04-04 | Biocine Spa | Mouse model for helicobacter pylori infection |
KR100478617B1 (en) * | 1994-12-07 | 2005-05-16 | 아이덱 파마슈티칼즈 코포레이션 | Induction of cytotoxic t-lymphocyte responses |
US5616342A (en) * | 1995-04-11 | 1997-04-01 | Pdt, Inc. | Emulsioin suitable for administering a poorly water-soluble photosensitizing compound and use thereof |
US6034073A (en) * | 1995-04-24 | 2000-03-07 | Novavax, Inc. | Solvent detergent emulsions having antiviral activity |
US5718904A (en) * | 1995-06-02 | 1998-02-17 | American Home Products Corporation | Adjuvants for viral vaccines |
US6488933B2 (en) | 1995-07-05 | 2002-12-03 | Yeda Research And Development Co. Ltd. | Preparations for the treatment of T cell mediated diseases |
ATE355375T1 (en) | 1996-01-04 | 2006-03-15 | Novartis Vaccines & Diagnostic | BACTERIOFERRITIN FROM HELICOBACTER PYLORI |
WO1997029773A1 (en) * | 1996-02-13 | 1997-08-21 | The Nisshin Oil Mills, Ltd. | Vaccine-containing emulsion and vaccine-containing powder for oral administration and process for producing the same |
US6818222B1 (en) | 1997-03-21 | 2004-11-16 | Chiron Corporation | Detoxified mutants of bacterial ADP-ribosylating toxins as parenteral adjuvants |
US5980912A (en) * | 1997-03-25 | 1999-11-09 | Zonagen, Inc. | Chitosan induced immunopotentiation |
AU764483B2 (en) * | 1997-04-22 | 2003-08-21 | Croda Chemicals International Limited | Aqueous compositions comprising a lipid and a lanolin-derived surfactant, and their use |
GB9708066D0 (en) * | 1997-04-22 | 1997-06-11 | Woolcombers Group Plc | Compositions and their use |
AU8298298A (en) * | 1997-07-08 | 1999-02-08 | Chiron Corporation | Use of submicron oil-in-water emulsions with dna vaccines |
DE69842224D1 (en) | 1997-08-27 | 2011-05-26 | Childrens Hosp Medical Center | Molecular mimetics of meningococcal B epitopes |
AU1198599A (en) * | 1997-10-24 | 1999-05-17 | Neorx Corporation | Delivery vehicles for bioactive agents and uses thereof |
WO1999024578A2 (en) | 1997-11-06 | 1999-05-20 | Chiron S.P.A. | Neisserial antigens |
US7790856B2 (en) | 1998-04-07 | 2010-09-07 | Janssen Alzheimer Immunotherapy | Humanized antibodies that recognize beta amyloid peptide |
US20080050367A1 (en) | 1998-04-07 | 2008-02-28 | Guriq Basi | Humanized antibodies that recognize beta amyloid peptide |
US7964192B1 (en) | 1997-12-02 | 2011-06-21 | Janssen Alzheimer Immunotherapy | Prevention and treatment of amyloidgenic disease |
TWI239847B (en) | 1997-12-02 | 2005-09-21 | Elan Pharm Inc | N-terminal fragment of Abeta peptide and an adjuvant for preventing and treating amyloidogenic disease |
US7393630B2 (en) | 1997-12-16 | 2008-07-01 | Novartis Vaccines And Diagnostics, Inc. | Use of microparticles combined with submicron oil-in-water emulsions |
CA2314934C (en) | 1997-12-16 | 2006-08-29 | Chiron Corporation | Use of microparticles combined with submicron oil-in-water emulsions |
US6165481A (en) * | 1997-12-25 | 2000-12-26 | Nippon Petrochemicals Company, Inc. | Highly pure squalane, raw material for pharmaceuticals and cosmetics prepared by using the same and method for producing the same |
BR9906927A (en) | 1998-01-14 | 2001-11-20 | Chiron Spa | Neisseria meningitidis proteins |
GB9808932D0 (en) | 1998-04-27 | 1998-06-24 | Chiron Spa | Polyepitope carrier protein |
WO2001031019A2 (en) | 1999-10-29 | 2001-05-03 | Chiron Spa | Neisserial antigenic peptides |
EP2261347A3 (en) | 1998-05-01 | 2012-01-11 | Novartis Vaccines and Diagnostics, Inc. | Neisseria meningitidis antigens and compositions |
JP2002513773A (en) * | 1998-05-07 | 2002-05-14 | コリクサ コーポレイション | Adjuvant composition and use thereof |
EP2796148A3 (en) | 1998-05-29 | 2015-02-25 | Novartis Vaccines and Diagnostics, Inc. | Combination meningitidis B/C vaccines |
CA2337445A1 (en) * | 1998-07-16 | 2000-01-27 | Sumitomo Pharmaceuticals Co., Ltd. | Preparations for immunotherapy for cancer having bacterial somatic constituent as the active ingredient |
US6416763B1 (en) | 1998-08-28 | 2002-07-09 | Hawaii Biotechnology Group, Inc. | Recombinant nonstructural protein subunit vaccine against flaviviral infection |
WO2000039302A2 (en) | 1998-12-31 | 2000-07-06 | Chiron Corporation | Improved expression of hiv polypeptides and production of virus-like particles |
US7935805B1 (en) | 1998-12-31 | 2011-05-03 | Novartis Vaccines & Diagnostics, Inc | Polynucleotides encoding antigenic HIV Type C polypeptides, polypeptides and uses thereof |
SE9900496D0 (en) * | 1999-02-12 | 1999-02-12 | Pharmatrix Ab | Vaccine formulation |
SE9900495D0 (en) * | 1999-02-12 | 1999-02-12 | Pharmatrix Ab | Vaccine composition |
EP1154790B1 (en) * | 1999-02-26 | 2004-10-20 | Chiron S.r.l. | Enhancement of bactericidal activity of neisseria antigens with oligonucleotides containing cg motifs |
EP1574210B1 (en) * | 1999-02-26 | 2016-04-06 | Novartis Vaccines and Diagnostics, Inc. | Microemulsions with adsorbed macromolecules |
AU4673099A (en) | 1999-02-26 | 2000-09-14 | Chiron Corporation | Use of bioadhesives and adjuvants for the mucosal delivery of antigens |
EP2196472A3 (en) | 1999-04-14 | 2011-04-13 | Novartis Vaccines and Diagnostics, Inc. | Compositions and methods for generating an immune response utilizing alphavirus-based vector systems |
US7655252B2 (en) | 1999-04-28 | 2010-02-02 | The Regents Of The University Of Michigan | Antimicrobial nanoemulsion compositions and methods |
US7767216B2 (en) * | 1999-04-28 | 2010-08-03 | The Regents Of The University Of Michigan | Antimicrobial compositions and methods of use |
RU2245366C2 (en) | 1999-04-30 | 2005-01-27 | Чирон С.Р.Л. | Neisseria antigen, nucleic acid encoding its, their applying |
GB9911683D0 (en) | 1999-05-19 | 1999-07-21 | Chiron Spa | Antigenic peptides |
UA81216C2 (en) | 1999-06-01 | 2007-12-25 | Prevention and treatment of amyloid disease | |
GB9916529D0 (en) | 1999-07-14 | 1999-09-15 | Chiron Spa | Antigenic peptides |
US6562346B1 (en) | 1999-10-27 | 2003-05-13 | Chiron Corporation | Activation of HCV-specific T cells |
GB9928196D0 (en) | 1999-11-29 | 2000-01-26 | Chiron Spa | Combinations of B, C and other antigens |
DK1897555T3 (en) | 2000-01-17 | 2014-10-13 | Novartis Vaccines & Diagnostic | Supplemental OMV vaccine against meningococcus |
AU781622B2 (en) | 2000-04-25 | 2005-06-02 | Boehringer Ingelheim Animal Health USA Inc. | Vaccine comprising a tick cement protein |
EP1322292B1 (en) | 2000-09-28 | 2007-01-03 | Novartis Vaccines and Diagnostics, Inc. | Microparticle compositions and methods for the manufacture thereof |
DE60131670T2 (en) | 2000-10-18 | 2008-10-30 | Glaxosmithkline Biologicals S.A. | Vaccines against cancer diseases |
NZ593617A (en) | 2000-10-27 | 2012-04-27 | Novartis Vaccines & Diagnostic | Nucleic acids and proteins from streptococcus groups A & B |
EP1415005B1 (en) | 2000-12-07 | 2012-11-21 | Novartis Vaccines and Diagnostics, Inc. | Endogenous retroviruses up-regulated in prostate cancer |
CA2434546C (en) | 2001-01-12 | 2012-09-11 | Chiron Corporation | Induction of immune response by a replication-defective venezuelan equine encephalitis-sindbis chimeric virus replicon particle encoding an antigen |
MXPA03007766A (en) * | 2001-02-28 | 2004-03-16 | Akzo Nobel Nv | Injectable water-in-oil emulsions. |
GB0107661D0 (en) | 2001-03-27 | 2001-05-16 | Chiron Spa | Staphylococcus aureus |
GB0107658D0 (en) | 2001-03-27 | 2001-05-16 | Chiron Spa | Streptococcus pneumoniae |
CA2966716C (en) | 2001-05-22 | 2019-11-26 | The Government Of The United States Of America, As Represented By The Cretary, Department Of Health And Human Services | Development of mutations useful for attenuating dengue viruses and chimeric dengue viruses |
EP2545937A1 (en) * | 2001-06-05 | 2013-01-16 | The Regents Of The University Of Michigan | Nanoemulsion vaccines |
GB0115176D0 (en) | 2001-06-20 | 2001-08-15 | Chiron Spa | Capular polysaccharide solubilisation and combination vaccines |
US8481043B2 (en) | 2001-06-22 | 2013-07-09 | Cpex Pharmaceuticals, Inc. | Nasal immunization |
AU2002322358B2 (en) * | 2001-06-29 | 2009-06-18 | Novartis Vaccines And Diagnostics, Inc. | HCV E1E2 vaccine compositions |
WO2003004620A2 (en) | 2001-07-05 | 2003-01-16 | Chiron, Corporation | Polynucleotides encoding antigenic hiv type c polypeptides, polypeptides and uses thereof |
EP2280074A3 (en) | 2001-07-05 | 2011-06-22 | Novartis Vaccines and Diagnostics, Inc. | Polynucleotides encoding antigenic HIV type B and/or type C polypeptides, polypeptides and uses thereof |
GB0118249D0 (en) | 2001-07-26 | 2001-09-19 | Chiron Spa | Histidine vaccines |
GB0121591D0 (en) | 2001-09-06 | 2001-10-24 | Chiron Spa | Hybrid and tandem expression of neisserial proteins |
US20030026783A1 (en) | 2001-08-03 | 2003-02-06 | Amine Abina | Method of modulating neutralizing antibodies formation in mammals, and uses thereof in gene therapy, animal transgenesis and in functional inactivation of an endogenous proteins |
US7361352B2 (en) | 2001-08-15 | 2008-04-22 | Acambis, Inc. | Influenza immunogen and vaccine |
AR045702A1 (en) * | 2001-10-03 | 2005-11-09 | Chiron Corp | COMPOSITIONS OF ASSISTANTS. |
MX339524B (en) | 2001-10-11 | 2016-05-30 | Wyeth Corp | Novel immunogenic compositions for the prevention and treatment of meningococcal disease. |
ES2386386T3 (en) | 2001-12-12 | 2012-08-20 | Novartis Vaccines And Diagnostics S.R.L. | Immunization against Chlamydia trachomatis |
GB0201736D0 (en) * | 2002-01-25 | 2002-03-13 | Glaxo Group Ltd | DNA dosage forms |
EP2572707A3 (en) | 2002-02-20 | 2013-11-06 | Novartis Vaccines and Diagnostics, Inc. | Microparticles with adsorbed polypeptide-containing molecules |
WO2003072040A2 (en) | 2002-02-25 | 2003-09-04 | Elan Pharmaceuticals, Inc. | Administration of agents for the treatment of inflammation |
EP1480666B1 (en) | 2002-03-05 | 2012-06-13 | Ramot at Tel-Aviv University Ltd. | Immunizing composition and method for inducing an immune response against the beta-secretase cleavage site of amyloid precursor protein |
MY139983A (en) | 2002-03-12 | 2009-11-30 | Janssen Alzheimer Immunotherap | Humanized antibodies that recognize beta amyloid peptide |
US6861410B1 (en) * | 2002-03-21 | 2005-03-01 | Chiron Corporation | Immunological adjuvant compositions |
ATE545651T1 (en) | 2002-06-13 | 2012-03-15 | Novartis Vaccines & Diagnostic | VECTORS FOR EXPRESSING HML-2 POLYPEPTIDES |
JP4726485B2 (en) * | 2002-08-02 | 2011-07-20 | 大日本住友製薬株式会社 | Bacterial cell wall skeleton component formulation |
NZ538628A (en) * | 2002-08-12 | 2008-06-30 | Dynavax Tech Corp | Immunomodulatory compositions, methods of making, and methods of use thereof |
GB0220194D0 (en) | 2002-08-30 | 2002-10-09 | Chiron Spa | Improved vesicles |
WO2010011999A2 (en) | 2008-07-25 | 2010-01-28 | The Regents Of The University Of California | Methods and compositions for eliciting an amyloid-selective immune response |
AU2003279770A1 (en) | 2002-10-01 | 2004-04-23 | Novartis Vaccines And Diagnostics, Inc. | Anti-cancer and anti-infectious disease compositions and methods for using same |
US20060110736A1 (en) | 2002-10-07 | 2006-05-25 | John Donnelly | Hiv vaccine formulations |
HUE047780T2 (en) | 2002-10-11 | 2020-05-28 | Glaxosmithkline Biologicals Sa | Polypeptide-vaccines for broad protection against hypervirulent meningococcal lineages |
WO2008103472A2 (en) | 2007-02-23 | 2008-08-28 | Elan Pharmaceuticals, Inc. | Prevention and treatment of synucleinopathic and amyloidogenic disease |
TW200509968A (en) | 2002-11-01 | 2005-03-16 | Elan Pharm Inc | Prevention and treatment of synucleinopathic disease |
US8506959B2 (en) | 2002-11-01 | 2013-08-13 | Neotope Biosciences Limited | Prevention and treatment of synucleinopathic and amyloidogenic disease |
DK2279746T3 (en) | 2002-11-15 | 2013-11-25 | Novartis Vaccines & Diagnostic | SURFACE PROTEINS IN NEISSERIA MENINGITIDIS |
GB0227346D0 (en) | 2002-11-22 | 2002-12-31 | Chiron Spa | 741 |
JP2006520746A (en) * | 2002-12-27 | 2006-09-14 | カイロン コーポレイション | Immunogenic compositions comprising phospholipids |
CN102302776B (en) | 2003-01-30 | 2014-06-18 | 诺华疫苗和诊断有限公司 | Injectable vaccines against multiple meningococcal serogroups |
US7893096B2 (en) | 2003-03-28 | 2011-02-22 | Novartis Vaccines And Diagnostics, Inc. | Use of small molecule compounds for immunopotentiation |
SI1613346T1 (en) * | 2003-04-04 | 2013-02-28 | Pah Usa 15 Llc | Microfluidized oil-in-water emulsions and vaccine compositions |
GB0308198D0 (en) | 2003-04-09 | 2003-05-14 | Chiron Srl | ADP-ribosylating bacterial toxin |
US7731967B2 (en) | 2003-04-30 | 2010-06-08 | Novartis Vaccines And Diagnostics, Inc. | Compositions for inducing immune responses |
AU2004255526A1 (en) | 2003-05-07 | 2005-01-20 | Aventis Pasteur, Inc. | Method of enhanced immunogenicity to meningococcal vaccination |
EP2386313A1 (en) | 2003-05-07 | 2011-11-16 | Sanofi Pasteur, Inc. | Multivalent meningococcal derivatized polysaccharide-protein conjugates and vaccine |
US7358331B2 (en) | 2003-05-19 | 2008-04-15 | Elan Pharmaceuticals, Inc. | Truncated fragments of alpha-synuclein in Lewy body disease |
JP4820291B2 (en) | 2003-05-19 | 2011-11-24 | エラン ファーマシューティカルズ,インコーポレイテッド | A truncated fragment of alpha synuclein in Lewy body disease |
DE602004022286D1 (en) | 2003-06-02 | 2009-09-10 | Novartis Vaccines & Diagnostic | IMMUNOGENIC COMPOSITIONS BASED ON BIODEGRADABLE MICRO PARTICLES CONTAINING A DIPHTHERIA AND TETANO TOXOID |
US20050208083A1 (en) * | 2003-06-04 | 2005-09-22 | Nanobio Corporation | Compositions for inactivating pathogenic microorganisms, methods of making the compositons, and methods of use thereof |
CA2532369C (en) | 2003-07-31 | 2016-07-26 | Chiron Corporation | Immunogenic compositions for streptococcus pyogenes |
US20060035242A1 (en) | 2004-08-13 | 2006-02-16 | Michelitsch Melissa D | Prion-specific peptide reagents |
GB0323103D0 (en) | 2003-10-02 | 2003-11-05 | Chiron Srl | De-acetylated saccharides |
NZ546430A (en) | 2003-10-02 | 2009-04-30 | Novartis Vaccines & Diagnostic | Liquid vaccines for multiple meningococcal serogroups |
US20050074469A1 (en) * | 2003-10-03 | 2005-04-07 | Charles Signorino | Stable lipophilic emulsions for acrylic coating and method of making |
US20050158329A1 (en) * | 2004-01-21 | 2005-07-21 | Ghosh Swapan K. | Novel phytol derived immunoadjuvants and their use in vaccine formulations |
WO2005107797A1 (en) | 2004-03-09 | 2005-11-17 | Chiron Corporation | Influenza virus vaccines |
JP5393978B2 (en) | 2004-04-05 | 2014-01-22 | ゾエティス・ピー・エルエルシー | Microfluidized oil-in-water emulsion and vaccine composition |
US20080032384A1 (en) * | 2004-04-22 | 2008-02-07 | Takehiko Nomura | Pharmaceutical Preparation Containing Bacterial Cell Wall Skeleton |
GB0500787D0 (en) | 2005-01-14 | 2005-02-23 | Chiron Srl | Integration of meningococcal conjugate vaccination |
EP2272531A3 (en) | 2004-04-30 | 2011-04-13 | Novartis Vaccines and Diagnostics S.r.l. | Integration of meningococcal conjugate vaccination |
GB0409745D0 (en) | 2004-04-30 | 2004-06-09 | Chiron Srl | Compositions including unconjugated carrier proteins |
GB0410866D0 (en) | 2004-05-14 | 2004-06-16 | Chiron Srl | Haemophilius influenzae |
AU2005247910A1 (en) | 2004-05-21 | 2005-12-08 | Wyeth | Altered fibronectin-binding protein of Staphylococcus aureus |
ES2647491T3 (en) | 2004-05-21 | 2017-12-21 | Novartis Vaccines And Diagnostics, Inc. | Alphavirus vectors for influenza virus vaccines |
EP2583678A3 (en) | 2004-06-24 | 2013-11-13 | Novartis Vaccines and Diagnostics, Inc. | Small molecule immunopotentiators and assays for their detection |
JP2008504292A (en) | 2004-06-24 | 2008-02-14 | ノバルティス ヴァクシンズ アンド ダイアグノスティクス, インコーポレイテッド | Immune enhancement compounds |
FR2873386B1 (en) | 2004-07-22 | 2011-01-14 | Agence Francaise De Securite Sanitaire Des Aliments Afssa | VACCINE COMPOSITION AGAINST RHODOCOCCUS EQUI |
EP2612679A1 (en) | 2004-07-29 | 2013-07-10 | Novartis Vaccines and Diagnostics, Inc. | Immunogenic compositions for gram positive bacteria such as streptococcus agalactiae |
MX2007001679A (en) | 2004-08-09 | 2007-05-23 | Elan Pharm Inc | Prevention and treatment of synucleinopathic and amyloidogenic disease. |
BRPI0515125A (en) | 2004-08-30 | 2008-07-08 | Sanofi Pasteur Inc | multivalent meningococcal protein-derivatized polysaccharide conjugates and vaccine |
WO2006034320A2 (en) | 2004-09-21 | 2006-03-30 | Sanofi Pasteur, Inc. | Multivalent meningococcal derivatized polysaccharide-protein conjugates and vaccine |
TWI365074B (en) * | 2004-10-07 | 2012-06-01 | Wyeth Corp | Multivalent avian influenza vaccines |
WO2006055178A2 (en) | 2004-10-25 | 2006-05-26 | Merck & Co., Inc. | Anti-addl antibodies and uses thereof |
GB0424092D0 (en) | 2004-10-29 | 2004-12-01 | Chiron Srl | Immunogenic bacterial vesicles with outer membrane proteins |
US20100015211A1 (en) | 2004-11-01 | 2010-01-21 | Barnett Susan W | Combination Approaches For Generating Immune Responses |
WO2006062637A2 (en) | 2004-11-03 | 2006-06-15 | Novartis Vaccines And Diagnostics Inc. | Influenza vaccination |
AR052051A1 (en) | 2004-12-15 | 2007-02-28 | Neuralab Ltd | AB HUMANIZED ANTIBODIES USED TO IMPROVE COGNITION |
US9034345B2 (en) | 2005-01-27 | 2015-05-19 | Children's Hospital & Research Center Oakland | GNA1870-based vesicle vaccines for broad spectrum protection against diseases caused by Neisseria meningitidis |
GB0502095D0 (en) | 2005-02-01 | 2005-03-09 | Chiron Srl | Conjugation of streptococcal capsular saccharides |
NZ560929A (en) | 2005-02-18 | 2009-12-24 | Novartis Vaccines & Diagnostic | Immunogens from uropathogenic escherichia coli |
PL2351772T3 (en) | 2005-02-18 | 2017-01-31 | Glaxosmithkline Biologicals Sa | Proteins and nucleic acids from meningitis/sepsis-associated Escherichia coli |
AR053833A1 (en) | 2005-03-23 | 2007-05-23 | Glaxosmithkline Biolog Sa | IMMUNOGENETIC COMPOSITION |
US7709001B2 (en) | 2005-04-08 | 2010-05-04 | Wyeth Llc | Multivalent pneumococcal polysaccharide-protein conjugate composition |
ES2382048T3 (en) | 2005-04-08 | 2012-06-04 | Wyeth Llc | Multivalent pneumococcal protein-polysaccharide conjugate composition |
WO2006110699A1 (en) * | 2005-04-11 | 2006-10-19 | Nanobio Corporation | Quaternary ammonium halides for treatment of infectious conditions |
FR2888117B1 (en) * | 2005-07-07 | 2009-10-09 | Sanofi Pasteur Sa | VACCINE COMPOSITION COMPRISING A THERMOREVERSIBLE EMULSION |
US8703095B2 (en) * | 2005-07-07 | 2014-04-22 | Sanofi Pasteur S.A. | Immuno-adjuvant emulsion |
AR054822A1 (en) | 2005-07-07 | 2007-07-18 | Sanofi Pasteur | ADMISSION IMMUNE EMULSION |
MX2008001527A (en) * | 2005-08-02 | 2008-04-04 | Novartis Vaccines & Diagnostic | Reducing interference between oil-containing adjuvants and surfactant-containing antigens. |
CA2618974C (en) * | 2005-08-09 | 2014-01-28 | Nanobio Corporation | Nanoemulsion compositions having anti-inflammatory activity |
US7797337B2 (en) * | 2005-09-29 | 2010-09-14 | Scenera Technologies, Llc | Methods, systems, and computer program products for automatically associating data with a resource as metadata based on a characteristic of the resource |
EP1954309A2 (en) * | 2005-10-17 | 2008-08-13 | Novartis AG | Multiclade hiv vaccines |
EP2357000A1 (en) | 2005-10-18 | 2011-08-17 | Novartis Vaccines and Diagnostics, Inc. | Mucosal and systemic immunizations with alphavirus replicon particles |
US11707520B2 (en) | 2005-11-03 | 2023-07-25 | Seqirus UK Limited | Adjuvanted vaccines with non-virion antigens prepared from influenza viruses grown in cell culture |
CA2628158C (en) * | 2005-11-04 | 2015-12-15 | Novartis Vaccines And Diagnostics S.R.L. | Emulsions with free aqueous-phase surfactant as adjuvants for split influenza vaccines |
CA2628206A1 (en) | 2005-11-04 | 2007-05-10 | Novartis Vaccines And Diagnostics S.R.L. | Influenza vaccine with reduced amount of oil-in-water emulsion as adjuvant |
AU2011213757B2 (en) * | 2005-11-04 | 2013-07-25 | Seqirus UK Limited | Influenza vaccine with reduced amount of oil-in-water emulsion as adjuvant |
EP3714900A1 (en) * | 2005-11-04 | 2020-09-30 | Seqirus UK Limited | Adjuvanted vaccines with non-virion antigens prepared from influenza viruses grown in cell culture |
US20110180430A1 (en) * | 2005-11-04 | 2011-07-28 | Novartis Vaccines And Diagnostics Srl | Adjuvanted influenza vaccines including cytokine-inducing agents |
GB0522765D0 (en) | 2005-11-08 | 2005-12-14 | Chiron Srl | Combination vaccine manufacture |
CA2629193C (en) * | 2005-11-18 | 2016-03-29 | 3M Innovative Properties Company | Coatable compositions, coatings derived therefrom and microarrays having such coatings |
US7527801B2 (en) | 2005-11-22 | 2009-05-05 | Novartis Vaccines And Diagnostics, Inc. | Norovirus and Sapovirus antigens |
GB0524066D0 (en) | 2005-11-25 | 2006-01-04 | Chiron Srl | 741 ii |
TWI465248B (en) | 2005-12-22 | 2014-12-21 | Glaxosmithkline Biolog Sa | Streptococcus pneumoniae immunogenic composition comprising capsular saccharide conjugates, vaccine and kit comprising the same and uses thereof |
GB0607088D0 (en) | 2006-04-07 | 2006-05-17 | Glaxosmithkline Biolog Sa | Vaccine |
US8097245B2 (en) | 2005-12-28 | 2012-01-17 | Advanced Bionutrition Corporation | Delivery vehicle for probiotic bacteria comprising a dry matrix of polysaccharides, saccharides and polyols in a glass form and methods of making same |
FR2896162B1 (en) * | 2006-01-13 | 2008-02-15 | Sanofi Pasteur Sa | EMULSION OIL IN THERMOREVERSIBLE WATER |
BR122019013216B8 (en) | 2006-01-27 | 2021-07-27 | Seqirus Uk Ltd | immunological assay for analysis of an influenza vaccine |
CA2647100A1 (en) * | 2006-03-23 | 2007-09-27 | Novartis Ag | Methods for the preparation of imidazole-containing compounds |
ES2388556T3 (en) * | 2006-03-23 | 2012-10-16 | Novartis Ag | Immunopotentiating compounds |
EP2357184B1 (en) | 2006-03-23 | 2015-02-25 | Novartis AG | Imidazoquinoxaline compounds as immunomodulators |
CA2646349A1 (en) | 2006-03-24 | 2007-10-04 | Novartis Vaccines And Diagnostics Gmbh & Co Kg | Storage of influenza vaccines without refrigeration |
EP2476434A1 (en) | 2006-03-30 | 2012-07-18 | GlaxoSmithKline Biologicals S.A. | Immunogenic composition |
US20100285062A1 (en) | 2006-03-31 | 2010-11-11 | Novartis Ag | Combined mucosal and parenteral immunization against hiv |
US8784810B2 (en) | 2006-04-18 | 2014-07-22 | Janssen Alzheimer Immunotherapy | Treatment of amyloidogenic diseases |
WO2009017467A1 (en) | 2007-07-27 | 2009-02-05 | Elan Pharma International Limited | Treatment of amyloidogenic diseases |
TW200806315A (en) | 2006-04-26 | 2008-02-01 | Wyeth Corp | Novel formulations which stabilize and inhibit precipitation of immunogenic compositions |
WO2008042024A2 (en) | 2006-06-01 | 2008-04-10 | Elan Pharmaceuticals, Inc. | Neuroactive fragments of app |
US20110206692A1 (en) | 2006-06-09 | 2011-08-25 | Novartis Ag | Conformers of bacterial adhesins |
MX2008016280A (en) | 2006-06-29 | 2009-03-26 | Novartis Ag | Polypeptides from neisseria meningitidis. |
DK2422810T3 (en) | 2006-07-17 | 2014-11-24 | Glaxosmithkline Biolog Sa | Influenza vaccine |
US8926993B2 (en) | 2006-07-17 | 2015-01-06 | Aduro Biotech | Methods and compositions using Listeria for enhancing immunogenicity by prime boost |
KR101696727B1 (en) | 2006-07-17 | 2017-01-16 | 글락소스미스클라인 바이오로지칼즈 에스.에이. | Influenza vaccine |
GB0614460D0 (en) | 2006-07-20 | 2006-08-30 | Novartis Ag | Vaccines |
SG173337A1 (en) | 2006-07-21 | 2011-08-29 | California Inst Of Techn | Targeted gene delivery for dendritic cell vaccination |
EP2586790A3 (en) | 2006-08-16 | 2013-08-14 | Novartis AG | Immunogens from uropathogenic Escherichia coli |
EP3456348A1 (en) | 2006-09-11 | 2019-03-20 | Seqirus UK Limited | Making influenza virus vaccines without using eggs |
US9481912B2 (en) | 2006-09-12 | 2016-11-01 | Longhorn Vaccines And Diagnostics, Llc | Compositions and methods for detecting and identifying nucleic acid sequences in biological samples |
US8097419B2 (en) | 2006-09-12 | 2012-01-17 | Longhorn Vaccines & Diagnostics Llc | Compositions and method for rapid, real-time detection of influenza A virus (H1N1) swine 2009 |
US8080645B2 (en) | 2007-10-01 | 2011-12-20 | Longhorn Vaccines & Diagnostics Llc | Biological specimen collection/transport compositions and methods |
US8652782B2 (en) | 2006-09-12 | 2014-02-18 | Longhorn Vaccines & Diagnostics, Llc | Compositions and methods for detecting, identifying and quantitating mycobacterial-specific nucleic acids |
EP3795173A1 (en) | 2006-09-26 | 2021-03-24 | Infectious Disease Research Institute | Vaccine composition containing synthetic adjuvant |
US20090181078A1 (en) | 2006-09-26 | 2009-07-16 | Infectious Disease Research Institute | Vaccine composition containing synthetic adjuvant |
EP2086582B1 (en) | 2006-10-12 | 2012-11-14 | GlaxoSmithKline Biologicals s.a. | Vaccine comprising an oil in water emulsion adjuvant |
WO2008043774A1 (en) | 2006-10-12 | 2008-04-17 | Glaxosmithkline Biologicals S.A. | Vaccine comprising an oil in water emulsion adjuvant |
GB0622282D0 (en) | 2006-11-08 | 2006-12-20 | Novartis Ag | Quality control methods |
CN101553252A (en) | 2006-12-06 | 2009-10-07 | 诺华有限公司 | Vaccines including antigen from four strains of influenza virus |
GB0700562D0 (en) | 2007-01-11 | 2007-02-21 | Novartis Vaccines & Diagnostic | Modified Saccharides |
EP3067066B1 (en) | 2007-02-23 | 2019-03-27 | Prothena Biosciences Limited | Prevention and treatment of synucleinopathic and amyloidogenic disease |
US8003097B2 (en) | 2007-04-18 | 2011-08-23 | Janssen Alzheimer Immunotherapy | Treatment of cerebral amyloid angiopathy |
PE20090146A1 (en) | 2007-04-20 | 2009-03-23 | Glaxosmithkline Biolog Sa | IMMUNOGENIC COMPOSITION AGAINST THE INFLUENZA VIRUS |
US8747872B2 (en) | 2007-05-02 | 2014-06-10 | The Regents Of The University Of Michigan | Nanoemulsion therapeutic compositions and methods of using the same |
US20110097360A1 (en) | 2007-05-25 | 2011-04-28 | Claudio Donati | Streptococcus pneumoniae pilus antigens |
EA200901578A1 (en) | 2007-06-26 | 2010-08-30 | Глаксосмитклайн Байолоджикалс С.А. | VACCINE CONTAINING CONJUGATES OF CAPSULAR POLYSACCHARIDES STREPTOCOCCUS PNEUMONIAE |
AU2008269439B2 (en) | 2007-06-27 | 2013-12-19 | Novartis Ag | Low-additive influenza vaccines |
GB0713880D0 (en) | 2007-07-17 | 2007-08-29 | Novartis Ag | Conjugate purification |
GB0714963D0 (en) | 2007-08-01 | 2007-09-12 | Novartis Ag | Compositions comprising antigens |
CA2695399C (en) | 2007-08-02 | 2017-10-17 | Biondvax Pharmaceuticals Ltd. | Multimeric multiepitope influenza vaccines |
US9683256B2 (en) | 2007-10-01 | 2017-06-20 | Longhorn Vaccines And Diagnostics, Llc | Biological specimen collection and transport system |
US11041215B2 (en) | 2007-08-24 | 2021-06-22 | Longhorn Vaccines And Diagnostics, Llc | PCR ready compositions and methods for detecting and identifying nucleic acid sequences |
EP2185196B1 (en) | 2007-08-27 | 2014-06-11 | Longhorn Vaccines & Diagnostics, LLC | Immunogenic compositions and methods |
US10004799B2 (en) | 2007-08-27 | 2018-06-26 | Longhorn Vaccines And Diagnostics, Llc | Composite antigenic sequences and vaccines |
AU2008299376B2 (en) | 2007-09-12 | 2013-02-28 | Glaxosmithkline Biologicals S.A. | GAS57 mutant antigens and GAS57 antibodies |
EP2197497B1 (en) * | 2007-09-27 | 2016-06-01 | ImmunoVaccine Technologies Inc. | Use of liposomes in a carrier comprising a continuous hydrophobic phase for delivery of polynucleotides in vivo |
US11041216B2 (en) | 2007-10-01 | 2021-06-22 | Longhorn Vaccines And Diagnostics, Llc | Compositions and methods for detecting and quantifying nucleic acid sequences in blood samples |
WO2009085355A2 (en) | 2007-10-01 | 2009-07-09 | Longhorn Vaccines & Diagnostics Llc | Biological specimen collection and transport system and methods of use |
US20100209452A1 (en) * | 2007-10-03 | 2010-08-19 | Immunovaccine Technologies, Inc | Compositions comprising an antigen, an amphipathic compound and a hydrophobic carrier, and uses thereof |
JO3076B1 (en) | 2007-10-17 | 2017-03-15 | Janssen Alzheimer Immunotherap | Immunotherapy regimes dependent on apoe status |
BRPI0818545A2 (en) | 2007-10-19 | 2017-07-04 | Novartis Ag | meningococcal vaccine formulations |
PT2227248E (en) † | 2007-11-26 | 2014-08-27 | Novartis Ag | Adjuvanted glucans |
GB0810305D0 (en) | 2008-06-05 | 2008-07-09 | Novartis Ag | Influenza vaccination |
EP3067048B1 (en) | 2007-12-07 | 2018-02-14 | GlaxoSmithKline Biologicals SA | Compositions for inducing immune responses |
EP2231181B1 (en) | 2007-12-17 | 2016-02-17 | Marfl AB | New vaccine for the treatment of mycobacterium related disorders |
EP2227483B1 (en) | 2007-12-19 | 2017-04-19 | The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. | Soluble forms of hendra and nipah virus f glycoprotein and uses thereof |
GB0818453D0 (en) | 2008-10-08 | 2008-11-12 | Novartis Ag | Fermentation processes for cultivating streptococci and purification processes for obtaining cps therefrom |
KR101773114B1 (en) | 2007-12-21 | 2017-08-30 | 노파르티스 아게 | Mutant forms of streptolysin o |
US8791243B2 (en) | 2007-12-28 | 2014-07-29 | Onclave Therapeutics Limited | Treatment and prophylaxis of amyloidosis |
US8092813B1 (en) * | 2007-12-28 | 2012-01-10 | Novartis Ag | Polychlorinated biphenyls and squalene-containing adjuvants |
AU2009215364B2 (en) | 2008-02-21 | 2014-09-18 | Glaxosmithkline Biologicals S.A. | Meningococcal fHBP polypeptides |
US8506966B2 (en) | 2008-02-22 | 2013-08-13 | Novartis Ag | Adjuvanted influenza vaccines for pediatric use |
EP2631245A1 (en) | 2008-03-10 | 2013-08-28 | Children's Hospital & Research Center at Oakland | Chimeric factor H binding proteins (fHBP) containing a heterologous B domain and methods of use |
AU2009227674C1 (en) | 2008-03-18 | 2015-01-29 | Seqirus UK Limited | Improvements in preparation of influenza virus vaccine antigens |
EP2271360B1 (en) | 2008-04-16 | 2015-09-23 | GlaxoSmithKline Biologicals S.A. | Vaccine |
CN102056622B (en) * | 2008-06-05 | 2016-04-06 | 免疫疫苗技术有限公司 | Comprise the compositions of liposome, antigen, polynucleotide and the carrier containing the continuous phase of hydrophobic substance |
MX2010014358A (en) | 2008-06-20 | 2011-07-04 | Wyeth Llc | Compositions and methods of use of orf1358 from beta-hemolytic streptococcal strains. |
RU2011107757A (en) | 2008-08-01 | 2012-09-10 | Гамма Ваксинс Пти Лимитед (Au) | INFLUENZA VACCINES |
ES2761697T3 (en) | 2008-08-28 | 2020-05-20 | Novartis Ag | Process for preparing an oil-in-water emulsion containing squalene from yeast |
CA2737455A1 (en) | 2008-09-18 | 2010-03-25 | Novartis Ag | Vaccine adjuvant combinations |
US9067981B1 (en) | 2008-10-30 | 2015-06-30 | Janssen Sciences Ireland Uc | Hybrid amyloid-beta antibodies |
CA2745205A1 (en) | 2008-12-03 | 2010-06-10 | Protea Vaccine Technologies Ltd. | Glutamyl trna synthetase (gts) fragments |
MX337723B (en) | 2008-12-09 | 2016-03-15 | Pfizer Vaccines Llc | IgE CH3 PEPTIDE VACCINE. |
ES2467108T3 (en) | 2008-12-09 | 2014-06-11 | Gilead Sciences, Inc. | Toll type receiver modulators |
US9884105B2 (en) | 2008-12-16 | 2018-02-06 | Ology Bioservices, Inc. | Production of viral vaccine |
AU2010203223B9 (en) | 2009-01-05 | 2015-10-08 | Epitogenesis Inc. | Adjuvant compositions and methods of use |
CA2749367A1 (en) | 2009-01-12 | 2010-07-15 | Novartis Ag | Cna_b domain antigens in vaccines against gram positive bacteria |
KR20110117654A (en) | 2009-01-13 | 2011-10-27 | 트랜스진 에스.에이. | Use of a saccharomyces cerevisiae mitochondrial nucleic acids fraction for immune stimulation |
DK2396032T3 (en) | 2009-02-10 | 2016-12-19 | Seqirus Uk Ltd | Influenza vaccines with reduced amounts of squalene |
KR20110132373A (en) | 2009-02-10 | 2011-12-07 | 노파르티스 아게 | Influenza vaccine regimens for pandemic-associated strains |
AU2010212548A1 (en) | 2009-02-10 | 2011-09-15 | Novartis Ag | Influenza vaccines with increased amounts of H3 antigen |
WO2010100632A2 (en) | 2009-03-06 | 2010-09-10 | Novartis Ag | Chlamydia antigens |
US8765171B2 (en) | 2009-03-09 | 2014-07-01 | The Regents Of The University Of California | Methods and compositions for liposomal formulation of antigens and uses thereof |
EP2411045A1 (en) | 2009-03-24 | 2012-02-01 | Novartis AG | Combinations of meningococcal factor h binding protein and pneumococcal saccharide conjugates |
SG175092A1 (en) | 2009-04-14 | 2011-11-28 | Novartis Ag | Compositions for immunising against staphylococcus aerus |
EP2424565A1 (en) * | 2009-04-27 | 2012-03-07 | Novartis AG | Adjuvanted vaccines for protecting against influenza |
SI2401384T1 (en) | 2009-05-21 | 2013-01-31 | Novartis Ag | Reverse genetics using non-endogenous pol i promoters |
CA2763074C (en) | 2009-05-26 | 2021-02-23 | Moti Harel | Stable dry powder composition comprising biologically active microorganisms and/or bioactive materials and methods of making |
CN103764160A (en) | 2009-05-29 | 2014-04-30 | 诺华有限公司 | Assays for influenza virus hemagglutinins |
AU2010256461B2 (en) | 2009-06-05 | 2016-03-17 | Access To Advanced Health Institute | Synthetic glucopyranosyl lipid adjuvants |
CA2765099A1 (en) | 2009-06-10 | 2010-12-16 | New York University | Phosphorylated tau peptide for use in the treatment of tauopathy |
JP5551774B2 (en) | 2009-06-15 | 2014-07-16 | ナショナル ユニヴァーシティー オブ シンガポール | Influenza vaccines, compositions, and methods of use |
PE20110065A1 (en) | 2009-06-22 | 2011-01-31 | Wyeth Llc | COMPOSITIONS AND METHODS FOR PREPARING IMMUNOGENIC COMPOSITIONS OF STAPHYLOCOCCUS AUREUS SEROTYPES 5 AND 8 CAPSULAR POLYSACCHARIDE CONJUGATE |
US8568735B2 (en) | 2009-06-22 | 2013-10-29 | Wyeth Llc | Immunogenic compositions of Staphylococcus aureus antigens |
SG177533A1 (en) | 2009-07-07 | 2012-02-28 | Novartis Ag | Conserved escherichia coli immunogens |
RU2585227C2 (en) | 2009-07-15 | 2016-05-27 | Новартис Аг | Rsv f protein composition and methods for production thereof |
ES2526996T3 (en) | 2009-07-16 | 2015-01-19 | Novartis Ag | Detoxified immunogens from Escherichia coli |
JP5646620B2 (en) | 2009-07-17 | 2014-12-24 | インダストリー アカデミック コーポレーション ファウンデーション, ハルリム ユニバーシティー | Composition for enhancing immunity comprising oligonucleotide encapsulated in liposome and epitope |
DK2770061T3 (en) | 2009-07-24 | 2019-01-07 | Immune Design Corp | NON-INTEGRATING LENTIVIRUS VECTORS |
MX2012001194A (en) | 2009-07-30 | 2012-03-07 | Pfizer Vaccines Llc | Antigenic tau peptides and uses thereof. |
CN102666860B (en) | 2009-07-31 | 2015-06-17 | 诺华股份有限公司 | Reverse genetics systems |
GB0913680D0 (en) | 2009-08-05 | 2009-09-16 | Glaxosmithkline Biolog Sa | Immunogenic composition |
GB0913681D0 (en) | 2009-08-05 | 2009-09-16 | Glaxosmithkline Biolog Sa | Immunogenic composition |
BR112012004275A2 (en) | 2009-08-27 | 2016-11-16 | Novartis Ag | hybrid polypeptides including meningococcal fhbp sequences |
EP2865752A1 (en) | 2009-09-03 | 2015-04-29 | Pfizer Vaccines LLC | PCSK9 vaccine |
CA2773637A1 (en) | 2009-09-10 | 2011-03-17 | Novartis Ag | Combination vaccines against respiratory tract diseases |
PL2477987T3 (en) | 2009-09-14 | 2018-06-29 | Gilead Sciences, Inc. | Modulators of toll-like receptors |
GB0917002D0 (en) | 2009-09-28 | 2009-11-11 | Novartis Vaccines Inst For Global Health Srl | Improved shigella blebs |
GB0917003D0 (en) | 2009-09-28 | 2009-11-11 | Novartis Vaccines Inst For Global Health Srl | Purification of bacterial vesicles |
CN102724988B (en) | 2009-09-30 | 2014-09-10 | 诺华股份有限公司 | Expression of meningococcal fHBP polypeptides |
RU2603267C2 (en) | 2009-09-30 | 2016-11-27 | Новартис Аг | Conjugation of staphylococcus aureus type 5 and type 8 capsular polysaccharides |
SG10201505023TA (en) | 2009-10-09 | 2015-07-30 | Cbio Ltd | Chaperonin 10 Variants |
GB0918392D0 (en) | 2009-10-20 | 2009-12-02 | Novartis Ag | Diagnostic and therapeutic methods |
WO2011048560A1 (en) | 2009-10-20 | 2011-04-28 | Novartis Ag | Improved reverse genetics methods for virus rescue |
CN102917730A (en) | 2009-10-27 | 2013-02-06 | 诺华有限公司 | Modified meningococcal fHBP polypeptides |
GB0919117D0 (en) | 2009-10-30 | 2009-12-16 | Glaxosmithkline Biolog Sa | Process |
GB0919690D0 (en) | 2009-11-10 | 2009-12-23 | Guy S And St Thomas S Nhs Foun | compositions for immunising against staphylococcus aureus |
WO2011067758A2 (en) | 2009-12-02 | 2011-06-09 | Protea Vaccine Technologies Ltd. | Immunogenic fragments and multimers from streptococcus pneumoniae proteins |
DK2343052T3 (en) | 2009-12-03 | 2013-09-02 | Novartis Ag | HYDROPHIL FILTERING WHILE PREPARING VACCINE ADJUSTERS |
ES2573710T3 (en) | 2009-12-03 | 2016-06-09 | Novartis Ag | Circulation of components during homogenization and microfluidization of emulsions |
DE102009056883B4 (en) | 2009-12-03 | 2012-08-16 | Novartis Ag | Vaccine adjuvants and improved methods of making the same |
DE102009056871A1 (en) | 2009-12-03 | 2011-06-22 | Novartis AG, 4056 | Vaccine adjuvants and improved methods of making the same |
AU2010325751B2 (en) * | 2009-12-03 | 2014-05-08 | Novartis Ag | Arranging interaction and back pressure chambers for microfluidization |
DE102009056884B4 (en) | 2009-12-03 | 2021-03-18 | Novartis Ag | Vaccine Adjuvants and Improved Methods for Making Same |
CL2012001399A1 (en) | 2009-12-03 | 2013-03-08 | Novartis Ag | Method to manufacture adjuvant for vaccine (oil / water emulsion with squalene, polysorbate 80 and sorbitan trioleate), which comprises (i) forming the first emulsion in a homogenizer from one container to another to form a second emulsion, (ii) and microfluidizing the first emulsion to form second emulsion. |
CN107412754A (en) | 2009-12-22 | 2017-12-01 | 塞尔德克斯医疗公司 | Vaccine combination |
US20110159031A1 (en) | 2009-12-22 | 2011-06-30 | Baxter International Inc. | Vaccine to Influenza A Virus |
US9173954B2 (en) | 2009-12-30 | 2015-11-03 | Glaxosmithkline Biologicals Sa | Polysaccharide immunogens conjugated to E. coli carrier proteins |
US9504750B2 (en) | 2010-01-28 | 2016-11-29 | Advanced Bionutrition Corporation | Stabilizing composition for biological materials |
DK2529004T3 (en) | 2010-01-28 | 2017-09-25 | Advanced Bionutrition Corp | DRY GLASSY COMPOSITION INCLUDING A BIOACTIVE MATERIAL |
EP2353609A1 (en) | 2010-02-04 | 2011-08-10 | Sanofi Pasteur | Immunization compositions and methods |
GB201003333D0 (en) | 2010-02-26 | 2010-04-14 | Novartis Ag | Immunogenic proteins and compositions |
GB201003920D0 (en) | 2010-03-09 | 2010-04-21 | Glaxosmithkline Biolog Sa | Method of treatment |
MX2012010609A (en) | 2010-03-18 | 2012-10-03 | Novartis Ag | Adjuvanted vaccines for serogroup b meningococcus. |
CN110845585A (en) | 2010-03-30 | 2020-02-28 | 奥克兰儿童医院及研究中心 | Modified Factor H Binding Proteins (FHBP) and methods of use thereof |
GB201005625D0 (en) | 2010-04-01 | 2010-05-19 | Novartis Ag | Immunogenic proteins and compositions |
EP2558069A1 (en) | 2010-04-13 | 2013-02-20 | Novartis AG | Benzonapthyridine compositions and uses thereof |
ES2453316T5 (en) | 2010-05-12 | 2017-07-18 | Novartis Ag | Improved procedures to prepare squalene |
AU2011254204B2 (en) | 2010-05-21 | 2015-08-20 | Seqirus UK Limited | Influenza virus reassortment method |
EP2576791B8 (en) | 2010-05-23 | 2016-12-21 | Aduro BioTech, Inc. | Methods and compositions using listeria for adjuvant treatment of cancer |
KR20130121699A (en) | 2010-05-28 | 2013-11-06 | 테트리스 온라인, 인코포레이티드 | Interactive hybrid asynchronous computer game infrastructure |
DK2575870T3 (en) | 2010-06-04 | 2017-02-13 | Wyeth Llc | vaccine Formulations |
US8895017B2 (en) | 2010-06-07 | 2014-11-25 | Pfizer Inc. | HER-2 peptides and vaccines |
EP2575868A1 (en) | 2010-06-07 | 2013-04-10 | Pfizer Vaccines LLC | Ige ch3 peptide vaccine |
GB201009861D0 (en) | 2010-06-11 | 2010-07-21 | Novartis Ag | OMV vaccines |
US10478483B2 (en) | 2010-06-25 | 2019-11-19 | Glaxosmithkline Biologicals Sa | Combinations of meningococcal factor H binding proteins |
ES2649896T3 (en) | 2010-07-06 | 2018-01-16 | Glaxosmithkline Biologicals Sa | Cationic emulsions of oil in water |
US9192661B2 (en) | 2010-07-06 | 2015-11-24 | Novartis Ag | Delivery of self-replicating RNA using biodegradable polymer particles |
RU2567808C2 (en) | 2010-07-14 | 2015-11-10 | Мерк Шарп Энд Домэ Корп. | Anti-addl monoclonal antibody and use thereof |
HRP20210242T4 (en) | 2010-08-23 | 2024-05-10 | Wyeth Llc | Stable formulations of neisseria meningitidis rlp2086 antigens |
DK2753352T4 (en) | 2010-09-03 | 2022-09-12 | Valneva Austria Gmbh | ISOLATED POLYPEPTIDE OF TOXIN A AND TOXIN B PROTEINS FROM C. DIFFICILE AND USES THEREOF |
CA2809758C (en) | 2010-09-10 | 2021-07-13 | Wyeth Llc | Non-lipidated variants of neisseria meningitidis orf2086 antigens |
GB201101665D0 (en) | 2011-01-31 | 2011-03-16 | Novartis Ag | Immunogenic compositions |
US8771709B2 (en) | 2010-09-20 | 2014-07-08 | Crucell Holland B.V. | Therapeutic vaccination against active Tuberculosis |
EP2627351B1 (en) | 2010-10-11 | 2018-12-26 | GlaxoSmithKline Biologicals SA | Antigen delivery platforms |
GB201017519D0 (en) | 2010-10-15 | 2010-12-01 | Novartis Vaccines Inst For Global Health S R L | Vaccines |
WO2012072769A1 (en) | 2010-12-01 | 2012-06-07 | Novartis Ag | Pneumococcal rrgb epitopes and clade combinations |
RU2570730C2 (en) | 2010-12-22 | 2015-12-10 | УАЙТ ЭлЭлСи | Stable immunogenic compositions of staphylococcus aureus antigens |
US20130315959A1 (en) | 2010-12-24 | 2013-11-28 | Novartis Ag | Compounds |
EP2667892B1 (en) | 2011-01-26 | 2019-03-27 | GlaxoSmithKline Biologicals SA | Rsv immunization regimen |
US20140079732A1 (en) | 2011-01-27 | 2014-03-20 | Gamma Vaccines Pty Limited | Combination vaccines |
MX2013009472A (en) | 2011-02-15 | 2013-10-28 | Immune Design Corp | Methods for enhancing immunogen specific immune responses by vectored vaccines. |
WO2012114323A1 (en) | 2011-02-22 | 2012-08-30 | Biondvax Pharmaceuticals Ltd. | Multimeric multiepitope polypeptides in improved seasonal and pandemic influenza vaccines |
EP2680883B1 (en) | 2011-03-02 | 2018-09-05 | Pfizer Inc | Pcsk9 vaccine |
US20140112950A1 (en) | 2011-03-02 | 2014-04-24 | Manmohan Singh | Combination vaccines with lower doses of antigen and/or adjuvant |
WO2012136653A1 (en) | 2011-04-08 | 2012-10-11 | Novvac Aps | Proteins and nucleic acids useful in vaccines targeting staphylococcus aureus |
EP3632463A1 (en) | 2011-04-08 | 2020-04-08 | Immune Design Corp. | Immunogenic compositions and methods of using the compositions for inducing humoral and cellular immune responses |
CA2834349A1 (en) | 2011-04-26 | 2012-11-01 | Molecular Express, Inc. | Liposomal formulations |
US20120288515A1 (en) | 2011-04-27 | 2012-11-15 | Immune Design Corp. | Synthetic long peptide (slp)-based vaccines |
EP2701743A4 (en) | 2011-04-27 | 2015-08-19 | Univ Northwestern | Antibodies selective for pathological tau dimers and prefibrillar pathological tau oligomers and their uses in treatment, diagnosis and monitoring of tauopathies |
SG194755A1 (en) | 2011-05-13 | 2013-12-30 | Novartis Ag | Pre-fusion rsv f antigens |
CN107837394A (en) | 2011-06-24 | 2018-03-27 | 埃皮托吉尼西斯有限公司 | Pharmaceutical composition as the combination of the carrier comprising selection of antigen specific immune conditioning agent, vitamin, tannin and flavonoids |
ITMI20111182A1 (en) | 2011-06-28 | 2012-12-29 | Canio Buonavoglia | VACCINE FOR CORONAVIRUS CANINO |
US11896636B2 (en) | 2011-07-06 | 2024-02-13 | Glaxosmithkline Biologicals Sa | Immunogenic combination compositions and uses thereof |
CA2840913C (en) | 2011-07-06 | 2020-01-21 | Novartis Ag | Oil-in-water emulsions that contain nucleic acids |
WO2013006837A1 (en) | 2011-07-06 | 2013-01-10 | Novartis Ag | Cationic oil-in-water emulsions |
EP2729168A2 (en) | 2011-07-06 | 2014-05-14 | Novartis AG | Immunogenic compositions and uses thereof |
WO2013009564A1 (en) | 2011-07-08 | 2013-01-17 | Novartis Ag | Tyrosine ligation process |
GB201112056D0 (en) | 2011-07-14 | 2011-08-31 | Univ Leuven Kath | Antibodies |
MX352522B (en) | 2011-07-26 | 2017-11-15 | Univ Mexico Nac Autonoma | Use of the peptide gk-1 expressed in the filamentous phage m13 for preparing pharmaceutical products that increase the effectiveness of the immune response induced by vaccine antigens or pathogens. |
CA2845872C (en) | 2011-08-22 | 2023-03-28 | Nanobio Corporation | Herpes simplex virus nanoemulsion vaccine |
GB201114923D0 (en) | 2011-08-30 | 2011-10-12 | Novartis Ag | Immunogenic proteins and compositions |
CA2848163C (en) | 2011-09-09 | 2020-10-27 | Nanobio Corporation | Nanoemulsion respiratory syncytial virus (rsv) subunit vaccine |
TR201909110T4 (en) | 2011-09-14 | 2019-07-22 | Glaxosmithkline Biologicals Sa | Methods for making saccharide-protein glycoconjugates. |
CN103930436A (en) | 2011-09-14 | 2014-07-16 | 诺华股份有限公司 | Escherichia coli vaccine combination |
AU2012311234B2 (en) | 2011-09-19 | 2017-09-28 | Axon Neuroscience Se | Protein-based therapy and diagnosis of tau-mediated pathology in Alzheimer's disease |
EP2573100A1 (en) | 2011-09-23 | 2013-03-27 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Total synthesis of the core tetrasaccharide of the lipopolysaccharide from Neisseria meningitidis |
BR112014008694A2 (en) | 2011-10-11 | 2017-06-20 | Novartis Ag | recombinant polycistronic nucleic acid molecules |
WO2013054199A2 (en) | 2011-10-12 | 2013-04-18 | Novartis Ag | Cmv antigens and uses thereof |
WO2013053899A1 (en) | 2011-10-12 | 2013-04-18 | Moeller Niels Iversen | Peptides derived from campylobacter jejuni and their use in vaccination |
CA2852857A1 (en) | 2011-10-20 | 2013-04-25 | Novartis Ag | Adjuvanted influenza b virus vaccines for pediatric priming |
US9493517B2 (en) | 2011-11-07 | 2016-11-15 | Glaxosmithkline Biologicals Sa | Conjugates comprising an antigen and a carrier molecule |
EP2780035A1 (en) | 2011-11-14 | 2014-09-24 | Novartis AG | Immunogenic complexes of polyanionic carbomers and env polypeptides and methods of manufacture and use thereof |
EP2785372B1 (en) | 2011-11-28 | 2019-06-19 | Janssen Vaccines & Prevention B.V. | Influenza virus vaccines and uses thereof |
WO2013083753A2 (en) | 2011-12-07 | 2013-06-13 | Institut Pasteur | Identification of a swine parecho-like virus and applications |
RU2014127714A (en) | 2011-12-08 | 2016-01-27 | Новартис Аг | TOXIN VACCINE Clostridium difficile |
ES2564138T3 (en) | 2011-12-12 | 2016-03-18 | Novartis Ag | Influenza Virus Hemagglutinin Assay |
US20150044251A1 (en) | 2011-12-23 | 2015-02-12 | Novartis Ag | Stable compositions for immunising against staphylococcus aureus |
WO2013112916A1 (en) | 2012-01-26 | 2013-08-01 | Longhorn Vaccines And Diagnostics, Llc | Composite antigenic sequences and vaccines |
TR201908003T4 (en) | 2012-02-07 | 2019-06-21 | Infectious Disease Res Inst | Advanced adjuvant formulations containing TLR4 agonists and their method of use. |
JP2015509713A (en) | 2012-02-24 | 2015-04-02 | ノバルティス アーゲー | Pili protein and composition |
EP2820126B1 (en) | 2012-03-02 | 2017-05-17 | Seqirus UK Limited | Influenza virus reassortment |
MX2014010417A (en) | 2012-03-08 | 2014-09-22 | Novartis Ag | Adjuvanted formulations of booster vaccines. |
EP4043029A1 (en) | 2012-03-09 | 2022-08-17 | Pfizer Inc. | Neisseria meningitidis compositions and methods thereof |
SA115360586B1 (en) | 2012-03-09 | 2017-04-12 | فايزر انك | Neisseria meningitidis compositions and methods thereof |
NZ628385A (en) | 2012-03-12 | 2016-09-30 | Crucell Holland Bv | Batches of recombinant adenovirus with altered terminal ends |
US8932607B2 (en) | 2012-03-12 | 2015-01-13 | Crucell Holland B.V. | Batches of recombinant adenovirus with altered terminal ends |
US9125870B2 (en) | 2012-03-22 | 2015-09-08 | Crucell Holland B.V. | Vaccine against RSV |
NZ630649A (en) | 2012-03-22 | 2016-12-23 | Janssen Vaccines & Prevention Bv | Vaccine against rsv |
EP3061451B1 (en) | 2012-03-23 | 2019-05-08 | Pitney Pharmaceuticals Pty Limited | Kinase inhibitors for the treatment of cancer |
GB201205189D0 (en) | 2012-03-23 | 2012-05-09 | Glaxosmithkline Biolog Sa | Novel medical use |
KR102070472B1 (en) | 2012-03-30 | 2020-01-29 | 이뮨 디자인 코포레이션 | Lentiviral vector particles having improved transduction efficiency for cells expressing dc-sign |
WO2013150518A1 (en) | 2012-04-01 | 2013-10-10 | Rappaport Family Institute For Research In The Medical Sciences | Extracellular matrix metalloproteinase inducer (emmprin) peptides and binding antibodies |
US20150050311A1 (en) | 2012-04-05 | 2015-02-19 | Ludwig-Maximilians-Universitat München | Novel method for the preparation of a strain-adapted vaccine |
US10279026B2 (en) | 2012-04-26 | 2019-05-07 | Glaxosmithkline Biologicals Sa | Antigens and antigen combinations |
WO2013160335A2 (en) | 2012-04-26 | 2013-10-31 | Novartis Ag | Antigens and antigen combinations |
WO2013164754A2 (en) | 2012-05-04 | 2013-11-07 | Pfizer Inc. | Prostate-associated antigens and vaccine-based immunotherapy regimens |
RS57420B1 (en) | 2012-05-16 | 2018-09-28 | Immune Design Corp | Vaccines for hsv-2 |
RU2014151567A (en) | 2012-05-22 | 2016-07-10 | Новартис Аг | CONJUGATE MENINGOCOCCA SEROGRAPH X |
US8735359B2 (en) | 2012-05-24 | 2014-05-27 | Orban Biotech Llc | Combinations of modalities for the treatment of diabetes |
WO2013182498A1 (en) | 2012-06-04 | 2013-12-12 | Novartis Ag | Improved safety testing |
US20150150963A1 (en) | 2012-06-05 | 2015-06-04 | The Australian National University | Vaccination with interleukin-4 antagonists |
KR102057217B1 (en) | 2012-06-20 | 2020-01-22 | 에스케이바이오사이언스 주식회사 | Multivalent pneumococcal polysaccharide-protein conjugate composition |
KR20150033703A (en) | 2012-06-27 | 2015-04-01 | 오르반 바이오테크 엘엘씨 | CTLA4 fusion proteins for the treatment of diabetes |
EP3608401A1 (en) | 2012-07-05 | 2020-02-12 | Ohio State Innovation Foundation | Compositions and methods related to viral vaccines |
CN104853770A (en) | 2012-07-06 | 2015-08-19 | 诺华股份有限公司 | Immunogenic compositions and uses thereof |
MX2015000446A (en) | 2012-07-24 | 2015-03-12 | Sanofi Pasteur | Vaccine compositions for prevention against dengue virus infection. |
WO2014016360A1 (en) | 2012-07-24 | 2014-01-30 | Sanofi Pasteur | Vaccine compositions |
WO2014039189A1 (en) | 2012-08-01 | 2014-03-13 | Mcnally Elizabeth | Mitigating tissue damage and fibrosis via latent transforming growth factor beta binding protein (ltbp4) |
CN104837812B (en) | 2012-08-06 | 2017-09-26 | 皮特尼制药股份有限公司 | Treat the compound of the related disease of mTOR paths |
US9517274B2 (en) | 2012-08-16 | 2016-12-13 | Pfizer Inc. | Glycoconjugation processes and compositions |
ES2737024T3 (en) | 2012-08-31 | 2020-01-09 | Glaxosmithkline Biologicals Sa | Proteins stabilized for immunization against Staphylococcus aureus |
CN104582723A (en) | 2012-08-31 | 2015-04-29 | 诺华股份有限公司 | Stabilised proteins for immunising against staphylococcus aureus |
EP2892553A1 (en) | 2012-09-06 | 2015-07-15 | Novartis AG | Combination vaccines with serogroup b meningococcus and d/t/p |
EP4056198A3 (en) | 2012-09-18 | 2022-12-07 | GlaxoSmithKline Biologicals SA | Outer membrane vesicles |
AU2013326584B2 (en) | 2012-10-02 | 2016-12-01 | Glaxosmithkline Biologicals Sa | Nonlinear saccharide conjugates |
US9855325B2 (en) | 2012-10-03 | 2018-01-02 | Glaxosmithkline Biologicals Sa | Immunogenic composition |
WO2014055825A1 (en) | 2012-10-04 | 2014-04-10 | The United States Of America, As Represented By The Secretary, Department Of Health & Human Services | A formulation of mycobacterial components as an adjuvant for inducing th17 responses |
GB201218195D0 (en) | 2012-10-10 | 2012-11-21 | Istituto Zooprofilattico Sperimentale Delle Venezie | Composition |
CA2886938A1 (en) | 2012-10-12 | 2014-04-17 | Glaxosmithkline Biologicals S.A. | Non-cross-linked acellular pertussis antigens for use in combination vaccines |
US9987344B2 (en) | 2012-11-30 | 2018-06-05 | Glaxosmithkline Biologicals Sa | Pseudomonas antigens and antigen combinations |
BR112015012515B1 (en) | 2012-11-30 | 2023-04-11 | Sanofi Pasteur | USE OF ANTIGENS, NUCLEIC ACID CONSTRUCTS OR VIRAL VECTORS CAPABLE OF EXPRESSING A VIRUS-LIKE PARTICLE (VLP) OF DENGUE AND A VACCINE AGAINST MEASLES, A VACCINE AGAINST MUMPS AND A VACCINE AGAINST RUBELLA |
AU2013354219A1 (en) | 2012-12-03 | 2015-07-02 | Novartis Ag | Reassortant influenza a viren |
HUE061273T2 (en) | 2012-12-05 | 2023-06-28 | Glaxosmithkline Biologicals Sa | Immunogenic composition |
KR20140075196A (en) | 2012-12-11 | 2014-06-19 | 에스케이케미칼주식회사 | Multivalent pneumococcal polysaccharide-protein conjugate composition |
KR20140075201A (en) | 2012-12-11 | 2014-06-19 | 에스케이케미칼주식회사 | Multivalent pneumococcal polysaccharide-protein conjugate composition |
CA2895149C (en) | 2012-12-17 | 2023-08-22 | Pitney Pharmaceuticals Pty Limited | Treatment of diseases involving mucin |
CA2894260A1 (en) | 2012-12-18 | 2014-06-26 | Glaxosmithkline Biologicals S.A. | Conjugates for protecting against diphtheria and/or tetanus |
PT3363806T (en) | 2012-12-20 | 2022-12-16 | Pfizer | Glycoconjugation process |
JP6286445B2 (en) | 2012-12-24 | 2018-02-28 | セル・アイディアズ・ピーティーワイ・リミテッド | Vaccine for treatment of cancer and composition for enhancing vaccine efficacy |
US10258682B2 (en) | 2013-01-16 | 2019-04-16 | The United States Of America, As Represented By The Secretary, Department Of Health & Human Services | Attenuated chlamydia vaccine |
AU2014214844B2 (en) | 2013-02-07 | 2017-12-14 | Children's Medical Center Corporation | Protein antigens that provide protection against pneumococcal colonization and/or disease |
MX362793B (en) | 2013-03-08 | 2019-02-13 | Janssen Vaccines & Prevention Bv | Acellular pertussis vaccine. |
CA2903716C (en) | 2013-03-08 | 2019-04-09 | Pfizer Inc. | Immunogenic fusion polypeptides |
CN111334530A (en) | 2013-03-13 | 2020-06-26 | 诺华股份有限公司 | Influenza B virus reassortment |
EP2988780B1 (en) | 2013-04-25 | 2018-12-26 | Janssen Vaccines & Prevention B.V. | Stabilized soluble prefusion rsv f polypeptides |
KR20160030097A (en) | 2013-05-10 | 2016-03-16 | 노파르티스 아게 | Avoiding narcolepsy risk in influenza vaccines |
EP2998322A4 (en) | 2013-05-14 | 2016-12-14 | Shanghai Hycharm Inc | Epitope vaccine for low immunogenic protein and preparing method and usage thereof |
WO2015132619A1 (en) | 2013-05-15 | 2015-09-11 | The Governors Of The University Of Alberta | E1e2 hcv vaccines and methods of use |
EP3004142B1 (en) | 2013-05-30 | 2020-09-30 | Janssen Vaccines & Prevention B.V. | Influenza virus vaccines and uses thereof |
DE202013005130U1 (en) | 2013-06-05 | 2013-09-10 | Novartis Ag | Influenza virus reassortment |
DE202013005100U1 (en) | 2013-06-05 | 2013-08-26 | Novartis Ag | Influenza virus reassortment |
EP3004332A2 (en) | 2013-06-06 | 2016-04-13 | Novartis AG | Influenza virus reassortment |
CN105408348B (en) | 2013-06-17 | 2021-07-06 | 扬森疫苗与预防公司 | Stabilized soluble pre-fusion RSV F polypeptides |
EP3016968B1 (en) | 2013-07-01 | 2019-06-26 | Newsouth Innovations Pty Limited | Diagnosis and treatment of autoimmune diseases |
US9975925B2 (en) | 2013-08-28 | 2018-05-22 | Glaxosmithkline Biologicals S.A. | Influenza antigens and antibodies |
KR102199096B1 (en) | 2013-09-08 | 2021-01-06 | 화이자 인코포레이티드 | Neisseria meningitidis compositions and methods thereof |
EP2851066A1 (en) | 2013-09-23 | 2015-03-25 | LTS LOHMANN Therapie-Systeme AG | Fixation of vaccine formulations on devices for epidermal immunisation by oily adjuvants |
EP2870974A1 (en) | 2013-11-08 | 2015-05-13 | Novartis AG | Salmonella conjugate vaccines |
US11191832B2 (en) | 2013-11-19 | 2021-12-07 | Prothena Biosciences Limited | Monitoring immunotherapy of Lewy body disease from constipation symptoms |
EP3077820A1 (en) | 2013-12-03 | 2016-10-12 | Evaxion Biotech ApS | Proteins and nucleic acids useful in vaccines targeting staphylococcus aureus |
EP3915579A1 (en) | 2013-12-31 | 2021-12-01 | Infectious Disease Research Institute | Single vial vaccine formulations |
WO2015112485A1 (en) | 2014-01-21 | 2015-07-30 | Immune Design Corp. | Compositions for use in the treatment of allergic conditions |
KR20210032013A (en) | 2014-01-21 | 2021-03-23 | 화이자 인코포레이티드 | Streptococcus pneumoniae capsular polysaccharides and conjugates thereof |
AU2015208820B2 (en) | 2014-01-21 | 2020-05-14 | Pfizer Inc. | Streptococcus pneumoniae capsular polysaccharides and conjugates thereof |
WO2016130569A1 (en) | 2015-02-09 | 2016-08-18 | Mj Biologics, Inc. | A composition comprising pedv antigens and methods for making and using the composition |
EP3104877B1 (en) | 2014-02-11 | 2020-01-22 | The USA, as represented by The Secretary, Department of Health and Human Services | Pcsk9 vaccine and methods of using the same |
EA035259B1 (en) | 2014-02-14 | 2020-05-21 | Иммьюн Дизайн Корп. | Immunotherapy of cancer through combination of local and systemic immune stimulation |
EP3104886B1 (en) | 2014-02-14 | 2018-10-17 | Pfizer Inc | Immunogenic glycoprotein conjugates |
GB2523399B (en) | 2014-02-25 | 2019-03-13 | Orban Tihamer | A composition comprising ten overlapping peptide fragments of the entire preproinsulin sequence |
WO2015138455A1 (en) | 2014-03-11 | 2015-09-17 | Regents Of The University Of Minnesota | Porcine epidemic diarrhea virus vaccines and methods of use thereof |
CN106103469B (en) | 2014-03-26 | 2020-11-27 | 葛兰素史密丝克莱恩生物有限公司 | Mutant staphylococcal antigens |
AU2015242154B2 (en) | 2014-04-03 | 2019-04-04 | Biondvax Pharmaceuticals Ltd. | Compositions of multimeric-multiepitope influenza polypeptides and their production |
US20150320706A1 (en) | 2014-05-12 | 2015-11-12 | Chiesi Farmaceutici S.P.A. | Formulations and methods of treating alzheimer's disease and other proteinopathies by combination therapy |
CN105288614A (en) * | 2014-06-18 | 2016-02-03 | 潘皓 | Vaccine composition and its preparation method |
WO2016001907A1 (en) | 2014-07-02 | 2016-01-07 | Prendergast Patrick T | Mogroside iv and mogroside v as agonist/stimulator/un-blocking agent for toll-like receptor 4 and adjuvant for use in human/animal vaccine and to stimulate immunity against disease agents. |
CA2952351C (en) | 2014-07-10 | 2023-10-17 | Antonietta IMPAGLIAZZO | Influenza virus vaccines and uses thereof |
EA201790024A1 (en) | 2014-07-11 | 2017-07-31 | Джилид Сайэнс, Инк. | MODULATORS OF TOLL-LIKE RECEPTORS FOR HIV TREATMENT |
MX2017000630A (en) | 2014-07-15 | 2017-04-27 | Immune Design Corp | Prime-boost regimens with a tlr4 agonist adjuvant and a lentiviral vector. |
NZ766003A (en) | 2014-07-23 | 2024-01-26 | Children’S Hospital & Res Center At Oakland | Factor h binding protein variants and methods of use thereof |
PL3848375T3 (en) | 2014-09-16 | 2024-05-06 | Gilead Sciences, Inc. | Methods of preparing intermediates for toll-like receptor modulators |
EA201790369A1 (en) | 2014-09-16 | 2017-10-31 | Джилид Сайэнс, Инк. | SOLID FORMS OF THOUGH-RECEPTOR MODULATOR |
JP7095990B2 (en) | 2014-09-18 | 2022-07-05 | シーダーズ-サイナイ メディカル センター | Compositions and Methods for Treating Fibrosis |
NZ730802A (en) | 2014-11-04 | 2021-12-24 | Janssen Vaccines & Prevention Bv | Therapeutic hpv16 vaccines |
AU2015252119A1 (en) | 2014-11-07 | 2016-05-26 | Takeda Vaccines, Inc. | Hand, foot, and mouth vaccines and methods of manufacture and use thereof |
MA40920A (en) | 2014-11-07 | 2017-09-12 | Takeda Vaccines Inc | VACCINES OF THE HAND, FOOT AND MOUTH, AND METHODS OF MANUFACTURING AND USE THEREOF |
US10611948B2 (en) | 2014-11-12 | 2020-04-07 | Lamberti Spa | Method of increasing lubricity of wellbore fluids |
US20180169211A1 (en) | 2014-11-13 | 2018-06-21 | Evaxion Biotech Aps | Peptides derived from acinetobacter baumannii and their use in vaccination |
ES2721306T3 (en) | 2014-12-02 | 2019-07-30 | Novartis Ag | Manufacture of compositions containing surfactant |
EP3031822A1 (en) | 2014-12-08 | 2016-06-15 | Novartis AG | Cytomegalovirus antigens |
US10434162B2 (en) | 2015-01-12 | 2019-10-08 | Evaxion Biotech Aps | Proteins and nucleic acids useful in vaccines targeting Klebsiella pneumoniae |
EP3047856A1 (en) | 2015-01-23 | 2016-07-27 | Novartis AG | Cmv antigens and uses thereof |
AU2016221318B2 (en) | 2015-02-19 | 2020-06-25 | Pfizer Inc. | Neisseria meningitidis compositions and methods thereof |
BR112017020178A2 (en) | 2015-03-26 | 2018-06-12 | Gpn Vaccines Pty Ltd | streptococcal vaccine |
EP3283634B1 (en) | 2015-04-14 | 2019-05-22 | Janssen Vaccines & Prevention B.V. | Recombinant adenovirus expressing two transgenes with a bidirectional promoter |
CN107708718B (en) | 2015-04-22 | 2022-01-11 | 西达-赛奈医疗中心 | Enterally delivered bitter oligopeptides for the treatment of type 2 diabetes |
WO2016179034A2 (en) | 2015-05-01 | 2016-11-10 | The Trustees Of The University Of Pennsylvania | Methods and compositions for stimulating immune response using potent immunostimulatory rna motifs |
AU2016258284C1 (en) | 2015-05-04 | 2020-09-03 | Pfizer Inc. | Group B Streptococcus polysaccharide-protein conjugates, methods for producing conjugates, immunogenic compositions comprising conjugates, and uses thereof |
US9976136B2 (en) | 2015-05-14 | 2018-05-22 | Longhorn Vaccines And Diagnostics, Llc | Rapid methods for the extraction of nucleic acids from biological samples |
JO3680B1 (en) | 2015-05-21 | 2020-08-27 | Dermavant Sciences GmbH | Topical pharmaceutical compositions |
US11617724B2 (en) | 2015-05-21 | 2023-04-04 | Dermavant Sciences GmbH | Topical pharmaceutical compositions |
JP2018524323A (en) | 2015-06-26 | 2018-08-30 | セキラス ユーケー リミテッド | Antigen matched influenza vaccine |
US20180201656A1 (en) | 2015-07-04 | 2018-07-19 | Evaxion Biotech Aps | Proteins and nucleic acids useful in vaccines targeting Pseudomonas Aeruginosa |
BR112018000296A2 (en) | 2015-07-07 | 2018-09-04 | Seqirus UK Limited | influenza potency tests |
KR20180026734A (en) | 2015-07-07 | 2018-03-13 | 얀센 백신스 앤드 프리벤션 비.브이. | Stabilized soluble fusion-pre-RSV F polypeptide |
PL3319633T3 (en) | 2015-07-07 | 2021-04-19 | Janssen Vaccines & Prevention B.V. | Vaccine against rsv |
EP3328215B1 (en) | 2015-07-29 | 2021-07-07 | Advanced BioNutrition Corp. | Stable dry probiotic compositions for special dietary uses |
SG10202001501QA (en) | 2015-08-20 | 2020-04-29 | Janssen Vaccines & Prevention Bv | Therapeutic hpv18 vaccines |
US11324816B2 (en) | 2015-08-31 | 2022-05-10 | Technovax, Inc. | Human respiratory syncytial virus (HRSV) virus-like particles (VLPS) based vaccine |
US10538557B2 (en) | 2015-09-02 | 2020-01-21 | Janssen Vaccines & Prevention B.V. | Stabilized viral class I fusion proteins |
GB201518684D0 (en) | 2015-10-21 | 2015-12-02 | Glaxosmithkline Biolog Sa | Vaccine |
GB201518668D0 (en) | 2015-10-21 | 2015-12-02 | Glaxosmithkline Biolog Sa | Immunogenic Comosition |
KR20180074699A (en) | 2015-11-09 | 2018-07-03 | 이뮨 디자인 코포레이션 | For the expression and administration of RNA replicons expressing heterologous nucleic acids, retroviral vectors |
MX2018005467A (en) | 2015-11-09 | 2018-12-11 | Immune Design Corp | Compositions comprising lentiviral vectors expressing il-12 and methods of use thereof. |
CN105251002B (en) * | 2015-11-13 | 2019-02-15 | 中国人民解放军第三军医大学 | A kind of oil-in-water type nano-emulsion adjuvant and its MRSA nano emulsion adjuvant vaccine and preparation method |
KR102136678B1 (en) | 2015-12-23 | 2020-07-22 | 화이자 인코포레이티드 | RSV F protein mutant |
SG11201805621SA (en) | 2016-01-19 | 2018-08-30 | Pfizer | Cancer vaccines |
WO2017144523A1 (en) | 2016-02-22 | 2017-08-31 | Evaxion Biotech Aps | Proteins and nucleic acids useful in vaccines targeting staphylococcus aureus |
EP3420092A1 (en) | 2016-02-23 | 2019-01-02 | Immune Design Corp. | Multigenome retroviral vector preparations and methods and systems for producing and using same |
CA3016867A1 (en) | 2016-03-11 | 2017-09-14 | Pfizer Inc. | Human cytomegalovirus gb polypeptide |
WO2017162741A1 (en) * | 2016-03-23 | 2017-09-28 | Intervet International B.V. | A combination vaccine against pcv2 virus and mycoplasma hyopneumoniae infection |
MX2018012095A (en) | 2016-04-05 | 2019-01-10 | Janssen Vaccines & Prevention Bv | Vaccine against rsv. |
WO2017174568A1 (en) | 2016-04-05 | 2017-10-12 | Janssen Vaccines & Prevention B.V. | Stabilized soluble pre-fusion rsv f proteins |
EP3452087A1 (en) | 2016-05-02 | 2019-03-13 | Janssen Vaccines & Prevention B.V. | Therapeutic hpv vaccine combinations |
DK3464331T3 (en) | 2016-05-30 | 2021-01-18 | Janssen Vaccines & Prevention Bv | STABILIZED PREFUSION RSV F PROTEINS |
WO2017207477A1 (en) | 2016-05-30 | 2017-12-07 | Janssen Vaccines & Prevention B.V. | Stabilized pre-fusion rsv f proteins |
GB201610599D0 (en) | 2016-06-17 | 2016-08-03 | Glaxosmithkline Biologicals Sa | Immunogenic Composition |
WO2017216384A1 (en) | 2016-06-17 | 2017-12-21 | Evaxion Biotech Aps | Vaccination targeting ichthyophthirius multifiliis |
BR112018075969A2 (en) | 2016-06-20 | 2019-04-02 | Janssen Vaccines & Prevention B.V. | powerful and balanced bidirectional promoter |
US11191822B2 (en) | 2016-06-22 | 2021-12-07 | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. | Pneumococcal polysaccharide-protein conjugate composition |
EP3269385A1 (en) | 2016-07-12 | 2018-01-17 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Pneumococcal polysaccharide-protein conjugate composition |
WO2017220787A1 (en) | 2016-06-24 | 2017-12-28 | Evaxion Biotech Aps | Vaccines against aearomonas salmonicida infection |
JP7229151B2 (en) | 2016-07-14 | 2023-02-27 | ヤンセン ファッシンズ アンド プリベンション ベーフェー | HPV vaccine |
WO2018015575A1 (en) | 2016-07-22 | 2018-01-25 | Evaxion Biotech Aps | Chimeric proteins for inducing immunity towards infection with s. aureus |
BR112019001486B1 (en) | 2016-07-28 | 2024-02-27 | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. | SACCHARIDE, VACCINE COMPOSITION COMPRISING THE SAME AND INTERMEDIATE COMPOUND FOR THE SYNTHESIS OF SAID SACCHARIDE |
US10751402B2 (en) | 2016-11-09 | 2020-08-25 | Pfizer Inc. | Immunogenic compositions and uses thereof |
BE1025162B9 (en) | 2016-12-06 | 2019-01-07 | Glaxosmithkline Biologicals Sa | PURIFICATION PROCESS FOR CAPSULAR POLYSACCHARIDES |
US11718648B2 (en) | 2017-01-05 | 2023-08-08 | Evaxion Biotech A/S | Vaccines targeting Pseudomonas aeruginosa |
EP3576759A4 (en) | 2017-01-31 | 2020-11-11 | Merck Sharp & Dohme Corp. | Methods for production of capsular polysaccharide protein conjugates from streptococcus pneumoniae serotype 19f |
CA3051801A1 (en) | 2017-01-31 | 2018-08-09 | Pfizer Inc. | Neisseria meningitidis compositions and methods thereof |
US11034978B2 (en) | 2017-02-09 | 2021-06-15 | Janssen Vaccines & Prevention B.V. | Potent and short promoter for expression of heterologous genes |
GB201703529D0 (en) | 2017-03-06 | 2017-04-19 | Cambridge Entpr Ltd | Vaccine composition |
US11254712B2 (en) | 2017-03-30 | 2022-02-22 | The University Of Queensland | Chimeric molecules and uses thereof |
WO2018183666A1 (en) | 2017-03-31 | 2018-10-04 | Boston Medical Center Corporation | Methods and compositions using highly converved pneumococcal surface proteins |
JP2020519663A (en) | 2017-05-17 | 2020-07-02 | ヤンセン ファッシンズ アンド プリベンション ベーフェーJanssen Vaccines & Prevention B.V. | Methods and compositions for inducing protective immunity against RSV infection |
AU2018283973A1 (en) | 2017-06-11 | 2020-01-16 | Molecular Express, Inc. | Methods and compositions for substance use disorder vaccine formulations and uses thereof |
ES2967001T3 (en) | 2017-06-23 | 2024-04-25 | Affinivax Inc | Immunogenic compositions |
CN111093650B (en) | 2017-09-07 | 2024-03-01 | 默沙东有限责任公司 | Pneumococcal polysaccharide and its use in immunogenic polysaccharide-carrier protein conjugates |
US11524069B2 (en) | 2017-09-13 | 2022-12-13 | Sanofi Pasteur | Human cytomegalovirus immunogenic composition |
EP3681533A1 (en) | 2017-09-15 | 2020-07-22 | Janssen Vaccines & Prevention B.V. | Method for the safe induction of immunity against rsv |
JP2021501147A (en) | 2017-10-25 | 2021-01-14 | ヤンセン ファーマシューティカルズ,インコーポレーテッド | Composition of Phosphorylated Tau Peptide and Its Use |
CN111615397A (en) | 2017-11-03 | 2020-09-01 | 武田疫苗股份有限公司 | Zika vaccine and immunogenic compositions and methods of use thereof |
NZ765694A (en) | 2017-12-06 | 2024-03-22 | Merck Sharp & Dohme Llc | Compositions comprising streptococcus pneumoniae polysaccharide-protein conjugates and methods of use thereof |
GB201721582D0 (en) | 2017-12-21 | 2018-02-07 | Glaxosmithkline Biologicals Sa | S aureus antigens and immunogenic compositions |
GB201721576D0 (en) | 2017-12-21 | 2018-02-07 | Glaxosmithkline Biologicals Sa | Hla antigens and glycoconjugates thereof |
HRP20220980T1 (en) | 2018-01-23 | 2022-11-11 | Janssen Vaccines & Prevention B.V. | Influenza virus vaccines and uses thereof |
WO2019145399A1 (en) | 2018-01-24 | 2019-08-01 | Evaxion Biotech Aps | Vaccines for prophylaxis of s. aureus infections |
US11633471B2 (en) | 2018-03-06 | 2023-04-25 | Unm Rainforest Innovations | Compositions and methods for reducing serum triglycerides |
WO2019175145A1 (en) | 2018-03-12 | 2019-09-19 | Janssen Vaccines & Prevention B.V. | Vaccines against urinary tract infections |
MX2020010606A (en) | 2018-04-09 | 2021-01-15 | Eisai R&D Man Co Ltd | Pladienolide compounds and their use. |
SG11202009907XA (en) | 2018-04-12 | 2020-11-27 | Eisai R&D Man Co Ltd | Pladienolide derivatives as spliceosome targeting agents for treating cancer |
GB201807303D0 (en) | 2018-05-03 | 2018-06-20 | London School Of Hygeine & Tropical Medicine | Glyconjugate vaccines |
JP2021524449A (en) | 2018-05-23 | 2021-09-13 | アーデーセー セラピューティクス ソシエテ アノニム | Molecular adjuvant |
EP3574915A1 (en) | 2018-05-29 | 2019-12-04 | Neovacs | Immunogenic product comprising il-4 and/or il-13 for treating disorders associated with aberrant il-4 and/or il 13 expression or activity |
US20210346371A1 (en) | 2018-06-01 | 2021-11-11 | Eisai R&D Management Co., Ltd. | Methods of using splicing modulators |
CA3099920A1 (en) | 2018-06-01 | 2019-12-05 | Eisai R&D Management Co., Ltd. | Splicing modulator antibody-drug conjugates and methods of use |
EP3810161A1 (en) | 2018-06-22 | 2021-04-28 | Synformulas GmbH | Non-viable bifidobacterium bifidum bacteria and uses thereof |
JP2021534761A (en) | 2018-08-23 | 2021-12-16 | グラクソスミスクライン バイオロジカルズ ソシエテ アノニム | Immunogenic proteins and compositions |
EP3870207A1 (en) | 2018-10-22 | 2021-09-01 | Evaxion Biotech ApS | Vaccines targeting m. catharrhalis |
MX2021005607A (en) | 2018-11-13 | 2021-06-30 | Janssen Vaccines & Prevention Bv | Stabilized pre-fusion rsv f proteins. |
JP2022512401A (en) | 2018-12-13 | 2022-02-03 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | Harboxy Diene Splicing Regulatory Antibodies-Drug Conjugates and Their Usage |
US20220296695A1 (en) | 2018-12-19 | 2022-09-22 | Merck Sharp & Dohme Corp. | Compositions comprising streptococcus pneumoniae polysaccharide-protein conjugates and methods of use thereof |
CA3125806A1 (en) | 2019-01-10 | 2020-07-16 | Expres2Ion Biotechnologies Aps | Glyco-engineered immunization antigens |
CA3127639A1 (en) | 2019-01-30 | 2020-08-06 | Glaxosmithkline Biologicals Sa | Oil/surfactant mixtures for self-emulsification |
AU2020219804A1 (en) | 2019-02-08 | 2021-08-19 | Ac Immune S.A. | Method of safe administration of phosphorylated Tau peptide vaccine |
EP3931206A1 (en) | 2019-02-27 | 2022-01-05 | Evaxion Biotech ApS | Vaccines targeting h. influenzae |
US11591377B2 (en) | 2019-04-24 | 2023-02-28 | Janssen Pharmaceuticals, Inc. | Heterologous administration of tau vaccines |
AU2020263900A1 (en) | 2019-04-25 | 2021-10-14 | Janssen Vaccines & Prevention B.V. | Recombinant influenza antigens |
US20220273787A1 (en) | 2019-05-15 | 2022-09-01 | Janssen Vaccines & Prevention B.V. | Co-administration of seasonal influenza vaccine and an adenovirus based respiratory syncytial virus vaccine |
CN113950333A (en) | 2019-05-15 | 2022-01-18 | 扬森疫苗与预防公司 | Prophylactic treatment of respiratory syncytial virus infection using adenovirus-based vaccines |
MX2021014363A (en) | 2019-05-25 | 2022-02-21 | Infectious Disease Res Inst | Composition and method for spray drying an adjuvant vaccine emulsion. |
EP3999093A4 (en) | 2019-07-19 | 2023-11-22 | Merck Sharp & Dohme LLC | Antigenic glycoprotein e polypeptides, compositions, and methods of use thereof |
EP3770269A1 (en) | 2019-07-23 | 2021-01-27 | GlaxoSmithKline Biologicals S.A. | Quantification of bioconjugate glycosylation |
EP4003410A1 (en) | 2019-07-31 | 2022-06-01 | Sanofi Pasteur, Inc. | Multivalent pneumococcal polysaccharide-protein conjugate compositions and methods of using the same |
WO2021043869A1 (en) | 2019-09-05 | 2021-03-11 | Janssen Vaccines & Prevention B.V. | Influenza virus vaccines and uses thereof |
WO2021048381A1 (en) | 2019-09-13 | 2021-03-18 | Evaxion Biotech Aps | Method for identifying stable mhc binding peptides using mass spectrometry |
WO2021048400A1 (en) | 2019-09-13 | 2021-03-18 | Evaxion Biotech Aps | Method for identifying t-cell epitopes |
EP3799884A1 (en) | 2019-10-01 | 2021-04-07 | GlaxoSmithKline Biologicals S.A. | Immunogenic compositions |
IL291821A (en) | 2019-10-02 | 2022-06-01 | Janssen Vaccines & Prevention Bv | Staphylococcus peptides and methods of use |
BR112022009545A2 (en) | 2019-11-18 | 2022-10-11 | Seqirus Pty Ltd | METHOD TO PRODUCE RECOMBINANT INFLUENZA VIRUS |
EP4087593A1 (en) | 2020-01-06 | 2022-11-16 | Evaxion Biotech A/S | Vaccines targeting neisseria gonorrhoeae |
EP4089170A4 (en) | 2020-01-10 | 2023-07-19 | Lg Chem, Ltd. | Composition comprising antigen-presenting cell co-expressing mhc and tumor antigen, and cancer treatment using same |
CA3168108A1 (en) | 2020-01-16 | 2021-07-22 | Janssen Pharmaceuticals, Inc. | Fimh mutant, compositions therewith and use thereof |
NL2030835B1 (en) | 2020-01-24 | 2022-12-29 | Aim Immunotech Inc | Methods, compositions, and vaccinces for treating a virus infection |
US11498944B2 (en) | 2020-01-31 | 2022-11-15 | Janssen Pharmaceuticals, Inc. | Compositions and methods for preventing and treating coronavirus infection—SARS-CoV-2 vaccines |
BR102020002165A2 (en) | 2020-01-31 | 2021-11-30 | Fundação Oswaldo Cruz | ANTIBODY, ITS USE, PHARMACEUTICAL COMPOSITION INCLUDING IT, METHOD OF DIAGNOSING FUNGAL INFECTIONS, DIAGNOSIS KIT OF FUNGAL INFECTIONS AND METHOD FOR TREATMENT OF FUNGAL INFECTIONS. |
AU2021218797A1 (en) | 2020-02-13 | 2022-08-25 | The Board Of Trustees Of The University Of Illinois | Vaccine and methods for detecting and preventing filariasis |
CN115698274A (en) | 2020-04-16 | 2023-02-03 | 帕尔免疫股份有限公司 | 28kDa GST protein from schistosoma for treating vasculitis |
WO2021211279A1 (en) | 2020-04-17 | 2021-10-21 | Regents Of The University Of Minnesota | SARS-CoV-2 SPIKE RECEPTOR BINDING DOMAIN AND COMPOSITIONS AND METHODS THEREOF |
EP3900739A1 (en) | 2020-04-21 | 2021-10-27 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Synthetic streptococcus pneumoniae saccharide conjugates to conserved membrane protein |
JP2023524860A (en) | 2020-05-11 | 2023-06-13 | ヤンセン ファーマシューティカルズ,インコーポレーテッド | SARS-CoV-2 vaccine |
WO2021228842A1 (en) | 2020-05-11 | 2021-11-18 | Janssen Pharmaceuticals, Inc. | Stabilized coronavirus spike protein fusion proteins |
AU2021271300A1 (en) | 2020-05-11 | 2023-02-02 | Janssen Pharmaceuticals, Inc. | RNA replicon encoding a stabilized corona virus spike protein |
US11857622B2 (en) | 2020-06-21 | 2024-01-02 | Pfizer Inc. | Human cytomegalovirus GB polypeptide |
EP4171629A1 (en) | 2020-06-29 | 2023-05-03 | GlaxoSmithKline Biologicals S.A. | Adjuvants |
BR112022026408A2 (en) | 2020-06-29 | 2023-01-17 | Janssen Vaccines & Prevention Bv | VACCINE COMBINATION AGAINST RESPIRATORY SYNCYTIAL VIRUS INFECTION |
US20230218526A1 (en) | 2020-06-30 | 2023-07-13 | Seqirus UK Limited | Cold filtration of oil-in-water emulsion adjuvants |
EP4175971A1 (en) | 2020-07-06 | 2023-05-10 | Janssen Pharmaceuticals, Inc. | Stabilized corona virus spike protein fusion proteins |
CA3187546A1 (en) | 2020-07-30 | 2022-02-03 | Thomas TROLLE | Process for preparation of neopepitope-containing vaccine agents |
JP2023538736A (en) | 2020-08-26 | 2023-09-11 | ファイザー・インク | Group B streptococcal polysaccharide-protein conjugates, methods for producing the conjugates, immunogenic compositions comprising the conjugates, and uses thereof |
KR20230110249A (en) | 2020-09-17 | 2023-07-21 | 니오베크스 | Immunogenic products comprising IgE fragments for the treatment of IgE-mediated inflammatory disorders |
JP2022060169A (en) | 2020-10-02 | 2022-04-14 | ファイザー・インク | Cell culture process for rsv f protein production |
CN112403140B (en) * | 2020-10-19 | 2022-07-19 | 傅光明 | Smoke-eliminating and dust-removing agent and preparation method thereof |
CN117202928A (en) | 2020-11-13 | 2023-12-08 | Icosavax股份有限公司 | Protein-based nanoparticle vaccine for metapneumovirus |
IL303954A (en) | 2021-01-12 | 2023-08-01 | Janssen Pharmaceuticals Inc | Fimh mutants, compositions therewith and use thereof |
AU2022218139A1 (en) | 2021-02-03 | 2023-09-21 | Pai Life Sciences Inc. | Vaccine and methods for preventing filariasis and dirofilariasis |
WO2022175477A1 (en) | 2021-02-19 | 2022-08-25 | Janssen Vaccines & Prevention B.V. | Stabilized pre-fusion rsv fb antigens |
WO2022175479A1 (en) | 2021-02-19 | 2022-08-25 | Janssen Vaccines & Prevention B.V. | Vaccine combinations against respiratory syncytial virus strain a and b infections |
MX2023009728A (en) | 2021-02-19 | 2023-08-30 | Sanofi Pasteur Inc | Meningococcal b recombinant vaccine. |
GB202102396D0 (en) | 2021-02-19 | 2021-04-07 | Adc Therapeutics Sa | Molecular adjuvant |
JP2024508799A (en) | 2021-02-24 | 2024-02-28 | ファイザー・インク | Novel druggable regions in human cytomegalovirus glycoprotein B polypeptide and methods for using the same |
CA3214415A1 (en) | 2021-04-01 | 2022-10-06 | Janssen Vaccines & Prevention B.V. | Stabilized pre-fusion piv3 f proteins |
EP4313135A1 (en) | 2021-04-01 | 2024-02-07 | Janssen Pharmaceuticals, Inc. | Production of e. coli o18 bioconjugates |
EP4333868A1 (en) | 2021-05-04 | 2024-03-13 | King Abdullah University Of Science And Technology | Immuogenic compositions of mutant sars-cov-2 n protein and gene and methods of use thereof |
WO2022248531A1 (en) | 2021-05-26 | 2022-12-01 | Evaxion Biotech A/S | Vaccination targeting intracellular pathogens |
WO2022261251A1 (en) | 2021-06-08 | 2022-12-15 | Glyde Bio Inc. | Immunogenic compositions comprising tumour-associated antigen |
EP4366762A1 (en) | 2021-07-05 | 2024-05-15 | Evaxion Biotech A/S | Vaccines targeting neisseria gonorrhoeae |
WO2023020993A1 (en) | 2021-08-16 | 2023-02-23 | Glaxosmithkline Biologicals Sa | Novel methods |
WO2023020992A1 (en) | 2021-08-16 | 2023-02-23 | Glaxosmithkline Biologicals Sa | Novel methods |
WO2023020994A1 (en) | 2021-08-16 | 2023-02-23 | Glaxosmithkline Biologicals Sa | Novel methods |
WO2023020939A1 (en) | 2021-08-17 | 2023-02-23 | Janssen Pharmaceuticals, Inc. | Sars-cov-2 vaccines |
WO2023047349A1 (en) | 2021-09-24 | 2023-03-30 | Janssen Pharmaceuticals, Inc. | Stabilized coronavirus spike protein fusion proteins |
WO2023047348A1 (en) | 2021-09-24 | 2023-03-30 | Janssen Pharmaceuticals, Inc. | Stabilized corona virus spike protein fusion proteins |
CN115106200A (en) * | 2021-10-25 | 2022-09-27 | 中国矿业大学(北京) | Coal dressing compound collecting agent, preparation method thereof and coal slime flotation method |
WO2023079528A1 (en) | 2021-11-05 | 2023-05-11 | King Abdullah University Of Science And Technology | Compositions suitable for use in a method for eliciting cross-protective immunity against coronaviruses |
WO2023079529A1 (en) | 2021-11-05 | 2023-05-11 | King Abdullah University Of Science And Technology | Re-focusing protein booster immunization compositions and methods of use thereof |
WO2023111725A1 (en) | 2021-12-14 | 2023-06-22 | Janssen Pharmaceuticals, Inc. | Sars-cov-2 vaccines |
WO2023110618A1 (en) | 2021-12-16 | 2023-06-22 | Janssen Vaccines & Prevention B.V. | Stabilized pre-fusion hmpv fusion proteins |
WO2023111306A1 (en) | 2021-12-17 | 2023-06-22 | Evaxion Biotech A/S | Personalized cancer therapy targeting normally non-expressed sequences |
WO2023196634A2 (en) | 2022-04-08 | 2023-10-12 | Flagship Pioneering Innovations Vii, Llc | Vaccines and related methods |
WO2023213393A1 (en) | 2022-05-04 | 2023-11-09 | Evaxion Biotech A/S | Staphylococcal protein variants and truncates |
WO2023217988A1 (en) | 2022-05-12 | 2023-11-16 | Janssen Vaccines & Prevention B.V. | Stabilized pre-fusion hmpv fusion proteins |
WO2023225562A1 (en) | 2022-05-17 | 2023-11-23 | Icosavax, Inc. | Multivalent vaccine for paramyxoviruses and uses thereof |
WO2024017682A1 (en) | 2022-07-18 | 2024-01-25 | Janssen Vaccines & Prevention B.V. | Rsv immunogens |
WO2024018061A1 (en) | 2022-07-22 | 2024-01-25 | Institut National de la Santé et de la Recherche Médicale | Use of bordetella strains for the treatment of chronic obstructive pulmonary disease |
US20240042021A1 (en) | 2022-08-01 | 2024-02-08 | Flagship Pioneering Innovations Vii, Llc | Immunomodulatory proteins and related methods |
WO2024061753A1 (en) | 2022-09-23 | 2024-03-28 | Janssen Vaccines & Prevention B.V. | Stabilized trimeric class i fusion proteins |
WO2024061759A1 (en) | 2022-09-23 | 2024-03-28 | Janssen Vaccines & Prevention B.V. | Stabilized coronavirus s proteins |
WO2024061757A1 (en) | 2022-09-23 | 2024-03-28 | Janssen Vaccines & Prevention B.V. | Pre-fusion human piv1 f proteins |
WO2024074584A1 (en) | 2022-10-06 | 2024-04-11 | Janssen Vaccines & Prevention B.V. | Stabilized pre-fusion piv3 f proteins |
Family Cites Families (33)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB888180A (en) * | 1900-01-01 | |||
US2008856A (en) * | 1935-07-23 | Cash begisteb | ||
US2017507A (en) * | 1934-06-29 | 1935-10-15 | Ruth L Moehling | Shoe cover |
DE1792410B2 (en) * | 1967-09-01 | 1980-03-13 | Apoteksvarucentralen Vitrum Apotekareaktiebolaget, Stockholm | Medicinal preparation for intravenous injection |
US3790665A (en) | 1968-02-23 | 1974-02-05 | Haver Lockhart Labor Inc | Injectable adjuvant,method of preparing same and compositions including such adjuvant |
US3678149A (en) * | 1970-01-26 | 1972-07-18 | Samuel J Prigal | Method of enhancing the action of a medicament |
US3833743A (en) * | 1970-03-17 | 1974-09-03 | Merck & Co Inc | Solubilization of water and aqueous solutions in non-aqueous liquids |
US3919411A (en) * | 1972-01-31 | 1975-11-11 | Bayvet Corp | Injectable adjuvant and compositions including such adjuvant |
FR2428051A1 (en) * | 1978-06-05 | 1980-01-04 | Anvar | NOVEL MURAMYL-PEPTIDE COMPOUNDS AND MEDICAMENTS CONTAINING THEM |
JPS5810365B2 (en) * | 1978-09-08 | 1983-02-25 | 田辺製薬株式会社 | fat emulsion |
US4409209A (en) * | 1979-10-12 | 1983-10-11 | Ciba-Geigy Corporation | Novel phosphorylmuramyl peptides and processes for the manufacture thereof |
FI803077A (en) * | 1979-10-12 | 1981-04-13 | Ciba Geigy Ag | FOERFARANDE FOER FRAMSTAELLNING AV MYRAMYLPEPTIDER |
US4522811A (en) * | 1982-07-08 | 1985-06-11 | Syntex (U.S.A.) Inc. | Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides |
EP0114787B1 (en) * | 1983-01-25 | 1991-09-25 | Ciba-Geigy Ag | Peptide derivatives |
JPS601122A (en) * | 1983-06-20 | 1985-01-07 | Green Cross Corp:The | Fat emulsion of biphenylylpropionic acid derivative |
FR2551758B1 (en) * | 1983-08-16 | 1986-01-31 | Anvar | MURAMYL-PEPTIDES AND STEROID DERIVATIVES HAVING MACROPHAGE ACTIVATION PROPERTIES |
US4606918A (en) * | 1983-08-22 | 1986-08-19 | Syntex (U.S.A.) Inc. | Polyoxypropylene-polyoxyethylene block polymer based adjuvants |
US4772466A (en) * | 1983-08-22 | 1988-09-20 | Syntex (U.S.A.) Inc. | Vaccines comprising polyoxypropylene-polyoxyethylene block polymer based adjuvants |
US4770874A (en) * | 1983-08-22 | 1988-09-13 | Syntex (U.S.A.) Inc. | Polyoxypropylene-polyoxyethylene block polymer based adjuvants |
FR2564096B1 (en) * | 1984-05-11 | 1988-02-19 | Anvar | LIPOPHILIC DERIVATIVES OF MURAMYLPEPTIDES HAVING MACROPHAGE ACTIVATION PROPERTIES, COMPOSITIONS CONTAINING THEM AND PROCESS FOR OBTAINING THE SAME |
US4784845A (en) * | 1985-09-16 | 1988-11-15 | American Cyanamid Company | Emulsion compostions for the parenteral administration of sparingly water soluble ionizable hydrophobic drugs |
DK585886A (en) * | 1985-12-24 | 1987-06-25 | Takeda Chemical Industries Ltd | IMMUNSTIMENTAL AGENTS AND USE THEREOF |
US4803070A (en) * | 1986-04-15 | 1989-02-07 | Ribi Immunochem Research Inc. | Immunological emulsion adjuvants for polysaccharide vaccines |
US4806350A (en) * | 1986-04-18 | 1989-02-21 | Norden Laboratories, Inc. | Vaccine formulation |
NZ221306A (en) * | 1986-08-15 | 1990-02-26 | Commw Scient Ind Res Org | 2-component immunoadjuvant comprising a mycobacterial free immunoadjuvant oil and a polycationic polyelectrolyte immunoadjuvant and vaccines thereof |
US5376369A (en) * | 1987-11-03 | 1994-12-27 | Syntex (U.S.A.) Inc. | Vaccine adjuvant |
DE3889521T2 (en) | 1987-11-03 | 1994-12-08 | Syntex Inc | Vaccine adjuvant. |
US4950645A (en) * | 1988-07-08 | 1990-08-21 | Immunotherapeutics, Inc. | Composition for macrophage activation |
DE69015222T2 (en) | 1989-02-04 | 1995-05-04 | Akzo Nv | Tocole as a vaccine adjuvant. |
US5709879A (en) * | 1990-06-29 | 1998-01-20 | Chiron Corporation | Vaccine compositions containing liposomes |
EP0640348A1 (en) * | 1993-07-26 | 1995-03-01 | Akzo Nobel N.V. | Oil-based and water-based adjuvant mixture |
US5961970A (en) * | 1993-10-29 | 1999-10-05 | Pharmos Corporation | Submicron emulsions as vaccine adjuvants |
CA2314934C (en) * | 1997-12-16 | 2006-08-29 | Chiron Corporation | Use of microparticles combined with submicron oil-in-water emulsions |
-
1990
- 1990-05-24 CA CA002017507A patent/CA2017507C/en not_active Expired - Lifetime
- 1990-05-24 JP JP2509214A patent/JPH0832638B2/en not_active Expired - Lifetime
- 1990-05-24 HU HU905459A patent/HU212924B/en active Protection Beyond IP Right Term
- 1990-05-24 WO PCT/US1990/002954 patent/WO1990014837A1/en unknown
- 1990-05-25 AT AT90305744T patent/ATE108327T1/en not_active IP Right Cessation
- 1990-05-25 PT PT94168A patent/PT94168B/en not_active IP Right Cessation
- 1990-05-25 DD DD90341001A patent/DD294633A5/en unknown
- 1990-05-25 IE IE190390A patent/IE64766B1/en active Protection Beyond IP Right Term
- 1990-05-25 DE DE199090305744T patent/DE399843T1/en active Pending
- 1990-05-25 ES ES90305744T patent/ES2033626T3/en not_active Expired - Lifetime
- 1990-05-25 DK DK90305744.6T patent/DK0399843T5/en active
- 1990-05-25 EP EP90305744A patent/EP0399843B1/en not_active Revoked
- 1990-05-25 DE DE69010574T patent/DE69010574T2/en not_active Revoked
-
1991
- 1991-11-15 GR GR91300063T patent/GR910300063T1/en unknown
-
1995
- 1995-04-07 US US08/418,870 patent/US6299884B1/en not_active Expired - Lifetime
- 1995-05-04 US US08/434,512 patent/US6451325B1/en not_active Expired - Lifetime
- 1995-07-06 HK HK107695A patent/HK107695A/en not_active IP Right Cessation
-
2002
- 2002-09-17 US US10/246,195 patent/US20090191226A2/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
DD294633A5 (en) | 1991-10-10 |
EP0399843A2 (en) | 1990-11-28 |
HUT61203A (en) | 1992-12-28 |
DE399843T1 (en) | 1991-05-02 |
ES2033626T3 (en) | 1994-10-16 |
GR910300063T1 (en) | 1991-11-15 |
DE69010574T2 (en) | 1994-10-27 |
CA2017507C (en) | 1996-11-12 |
US6299884B1 (en) | 2001-10-09 |
DE69010574D1 (en) | 1994-08-18 |
US20030147898A1 (en) | 2003-08-07 |
WO1990014837A1 (en) | 1990-12-13 |
US20090191226A2 (en) | 2009-07-30 |
EP0399843B1 (en) | 1994-07-13 |
DK0399843T5 (en) | 1994-09-19 |
HK107695A (en) | 1995-07-14 |
PT94168A (en) | 1991-01-08 |
HU212924B (en) | 1996-12-30 |
JPH0832638B2 (en) | 1996-03-29 |
IE901903L (en) | 1990-11-25 |
ATE108327T1 (en) | 1994-07-15 |
JPH05508385A (en) | 1993-11-25 |
CA2017507A1 (en) | 1990-11-25 |
ES2033626T1 (en) | 1993-04-01 |
PT94168B (en) | 2001-05-31 |
US6451325B1 (en) | 2002-09-17 |
EP0399843A3 (en) | 1992-09-02 |
IE64766B1 (en) | 1995-09-06 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
HU905459D0 (en) | Adjuvant preparation containing submicronal oil-drop emulsion | |
EP0489153A4 (en) | Vaccine compositions containing liposomes | |
CA2090104A1 (en) | Stabilized retinoid-containing skin care compositions | |
EP0428157A3 (en) | An emulsified composition | |
ZA929870B (en) | Adjuvants | |
JPS6479104A (en) | Water-in-oil type emulsified cosmetic in solid state | |
GR3000536T3 (en) | Penetration enhancement systems and the preparation thereof | |
EP0373424A3 (en) | Antiperspirant compositions | |
SE8903061L (en) | EMULSION BRAIN CONTAINING VERY THICK OIL | |
CA2176360A1 (en) | Pharmaceutical emulsion | |
EP0279641A3 (en) | Cosmetic compositions | |
EP0214568A3 (en) | Oil-in-water emulsion | |
CA2165157A1 (en) | Stable water-in-oil emulsions | |
ES2097840T3 (en) | VACCINE ADJUVANT INCLUDING A TETRAPOLIOL. | |
ZA851586B (en) | Silicone-free anti-foaming compositions | |
GR3004533T3 (en) | ||
WO1996032923A3 (en) | Anti-transpirants | |
DE50000033D1 (en) | Shampoo | |
DE3785323T2 (en) | COSMETIC COMPOSITION. | |
DE69418892T2 (en) | SELF-TEMPERATURE FORMULATION FOR THE FORMATION OF AN OIL-IN-WATER EMULSION | |
Sonalla | Vibrations of cantilever beams with various initial conditions | |
EP0262763A3 (en) | A retainer for rope or the like | |
IT1196817B (en) | Toxoplasmic antigens compsn. for diagnostic use | |
CA2031258A1 (en) | Clay grease and its preparation |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
AA1S | Information on application for a supplementary protection certificate |
Free format text: PRODUCT NAME: MF59 ADJUVANS INFLUENZA FELUELETI ANTIGENEKKEL/FOCETRIA; REGISTRATION NO/DATE: EU/1/07/385/001-004 20070502 Spc suppl protection certif: S0700006 Filing date: 20071031 Expiry date: 20100524 |
|
GB9A | Succession in title |
Owner name: NOVARTIS VACCINES AND DIAGNOSTICS, INC., US Free format text: FORMER OWNER(S): CHIRON CORP., US |
|
AA1S | Information on application for a supplementary protection certificate |
Free format text: PRODUCT NAME: PANADEMIA INFLUENZA VACCINE (SURFACE ANTIGEN, INACTIVATED, ADJUVANTED); REG. NO/DATE:C(2009)7585 20090929 Spc suppl protection certif: S1000004 Filing date: 20100326 Expiry date: 20100524 |