GB8725812D0 - Antibodies - Google Patents

Antibodies

Info

Publication number
GB8725812D0
GB8725812D0 GB878725812A GB8725812A GB8725812D0 GB 8725812 D0 GB8725812 D0 GB 8725812D0 GB 878725812 A GB878725812 A GB 878725812A GB 8725812 A GB8725812 A GB 8725812A GB 8725812 D0 GB8725812 D0 GB 8725812D0
Authority
GB
United Kingdom
Prior art keywords
antibodies
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
GB878725812A
Other versions
GB2197323A (en
GB2197323B (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
National Research Development Corp UK
National Research Development Corp of India
Original Assignee
National Research Development Corp UK
National Research Development Corp of India
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by National Research Development Corp UK, National Research Development Corp of India filed Critical National Research Development Corp UK
Publication of GB8725812D0 publication Critical patent/GB8725812D0/en
Publication of GB2197323A publication Critical patent/GB2197323A/en
Application granted granted Critical
Publication of GB2197323B publication Critical patent/GB2197323B/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/46—Hybrid immunoglobulins
    • C07K16/468—Immunoglobulins having two or more different antigen binding sites, e.g. multifunctional antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C07K2317/732—Antibody-dependent cellular cytotoxicity [ADCC]

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
GB8725812A 1986-11-05 1987-11-04 Antibodies Expired - Fee Related GB2197323B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB868626413A GB8626413D0 (en) 1986-11-05 1986-11-05 Antibodies

Publications (3)

Publication Number Publication Date
GB8725812D0 true GB8725812D0 (en) 1987-12-09
GB2197323A GB2197323A (en) 1988-05-18
GB2197323B GB2197323B (en) 1990-10-31

Family

ID=10606822

Family Applications (2)

Application Number Title Priority Date Filing Date
GB868626413A Pending GB8626413D0 (en) 1986-11-05 1986-11-05 Antibodies
GB8725812A Expired - Fee Related GB2197323B (en) 1986-11-05 1987-11-04 Antibodies

Family Applications Before (1)

Application Number Title Priority Date Filing Date
GB868626413A Pending GB8626413D0 (en) 1986-11-05 1986-11-05 Antibodies

Country Status (5)

Country Link
EP (1) EP0293405A1 (en)
JP (1) JPH01501201A (en)
AU (1) AU616870B2 (en)
GB (2) GB8626413D0 (en)
WO (1) WO1988003566A1 (en)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2621127B1 (en) * 1987-09-30 1992-01-31 Roussy Inst Gustave MONOCLONAL ANTIBODIES RECOGNIZING A GAMMA CHAIN EPITOPE OF HUMAN T CELL SURFACE RECEPTORS, LINE OF HYBRIDOMA CELLS PRODUCING THE SAME, AND USE OF THIS MONOCLONAL ANTIBODY
EP0334300A1 (en) * 1988-03-21 1989-09-27 Neorx Corporation The use of monoclonal antibodies and conjugates thereof as signals to direct sensitized effector cells to tumor sites
US5223426A (en) * 1988-12-15 1993-06-29 T Cell Sciences, Inc. Monoclonal antibodies reactive with defined regions of the t-cell antigen receptor
US5766947A (en) * 1988-12-14 1998-06-16 Astra Ab Monoclonal antibodies reactive with an epitope of a Vβ3.1 variable region of a T cell receptor
US5897861A (en) * 1989-06-29 1999-04-27 Medarex, Inc. Bispecific reagents for AIDS therapy
ATE144793T1 (en) * 1989-06-29 1996-11-15 Medarex Inc BISPECIFIC REAGENTS FOR AIDS THERAPY
US5858363A (en) * 1990-07-20 1999-01-12 Pharmacia & Upjohn Ab Target specific antibody-superantigen conjugates and their preparation
KR100189024B1 (en) * 1990-07-20 1999-06-01 존 해던쉬트롬 Target specific antibody-superantigen conjugates and their preparation
JP3105629B2 (en) † 1991-04-23 2000-11-06 サングスタット メディカル コーポレイション Cell activity regulating conjugates of members of specific binding pairs
US5587458A (en) * 1991-10-07 1996-12-24 Aronex Pharmaceuticals, Inc. Anti-erbB-2 antibodies, combinations thereof, and therapeutic and diagnostic uses thereof
US5945311A (en) * 1994-06-03 1999-08-31 GSF--Forschungszentrumfur Umweltund Gesundheit Method for producing heterologous bi-specific antibodies
DE122009000068I2 (en) * 1994-06-03 2011-06-16 Ascenion Gmbh Process for the preparation of heterologous bispecific antibodies
PL211872B1 (en) 2000-03-31 2012-07-31 Purdue Research Foundation Method of treatment using ligand-immunogen conjugates
JP5168538B2 (en) * 2007-05-24 2013-03-21 アボットジャパン株式会社 Antibody-antibody conjugates and application to diagnostic antibodies
EP3916011A1 (en) 2009-06-26 2021-12-01 Regeneron Pharmaceuticals, Inc. Readily isolated bispecific antibodies with native immunoglobulin format
CN103261220B (en) 2010-08-16 2016-06-15 诺夫免疫股份有限公司 For generating the method for polyspecific and multivalent antibody
ES2758051T3 (en) 2011-08-05 2020-05-04 Regeneron Pharma Humanized Universal Light Chain Mice
AR101262A1 (en) 2014-07-26 2016-12-07 Regeneron Pharma PURIFICATION PLATFORM FOR Bispecific Antibodies

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4474893A (en) * 1981-07-01 1984-10-02 The University of Texas System Cancer Center Recombinant monoclonal antibodies
CA1213229A (en) * 1982-04-12 1986-10-28 Gary S. David Antibodies having dual specificities, their preparation and uses therefor

Also Published As

Publication number Publication date
AU616870B2 (en) 1991-11-14
AU8156887A (en) 1988-06-01
WO1988003566A1 (en) 1988-05-19
GB8626413D0 (en) 1986-12-03
GB2197323A (en) 1988-05-18
EP0293405A1 (en) 1988-12-07
JPH01501201A (en) 1989-04-27
GB2197323B (en) 1990-10-31

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Legal Events

Date Code Title Description
732 Registration of transactions, instruments or events in the register (sect. 32/1977)
PCNP Patent ceased through non-payment of renewal fee

Effective date: 19931104