GB2587768B - Devices and methods for purification, detection and use of biological cells - Google Patents

Devices and methods for purification, detection and use of biological cells Download PDF

Info

Publication number
GB2587768B
GB2587768B GB2102155.5A GB202102155A GB2587768B GB 2587768 B GB2587768 B GB 2587768B GB 202102155 A GB202102155 A GB 202102155A GB 2587768 B GB2587768 B GB 2587768B
Authority
GB
United Kingdom
Prior art keywords
purification
detection
methods
devices
biological cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
GB2102155.5A
Other versions
GB202102155D0 (en
GB2587768A (en
Inventor
T Gjerde Douglas
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of GB202102155D0 publication Critical patent/GB202102155D0/en
Publication of GB2587768A publication Critical patent/GB2587768A/en
Application granted granted Critical
Publication of GB2587768B publication Critical patent/GB2587768B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/42—Selective adsorption, e.g. chromatography characterised by the development mode, e.g. by displacement or by elution
    • B01D15/428—Frontal mode
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 - B01D15/36
    • B01D15/3804—Affinity chromatography
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/16—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to the conditioning of the fluid carrier
    • B01D15/166—Fluid composition conditioning, e.g. gradient
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/42—Selective adsorption, e.g. chromatography characterised by the development mode, e.g. by displacement or by elution
    • B01D15/422—Displacement mode
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
GB2102155.5A 2014-04-03 2015-04-03 Devices and methods for purification, detection and use of biological cells Active GB2587768B (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201461974950P 2014-04-03 2014-04-03
US201462061636P 2014-10-08 2014-10-08
GB1618356.8A GB2539857B (en) 2014-04-03 2015-04-03 Devices and methods for purification, detection and use of biological cells

Publications (3)

Publication Number Publication Date
GB202102155D0 GB202102155D0 (en) 2021-03-31
GB2587768A GB2587768A (en) 2021-04-07
GB2587768B true GB2587768B (en) 2021-08-18

Family

ID=54241352

Family Applications (2)

Application Number Title Priority Date Filing Date
GB2102155.5A Active GB2587768B (en) 2014-04-03 2015-04-03 Devices and methods for purification, detection and use of biological cells
GB1618356.8A Active GB2539857B (en) 2014-04-03 2015-04-03 Devices and methods for purification, detection and use of biological cells

Family Applications After (1)

Application Number Title Priority Date Filing Date
GB1618356.8A Active GB2539857B (en) 2014-04-03 2015-04-03 Devices and methods for purification, detection and use of biological cells

Country Status (3)

Country Link
EP (1) EP3126027A4 (en)
GB (2) GB2587768B (en)
WO (1) WO2015154048A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201521784D0 (en) * 2015-12-10 2016-01-27 Univ Birmingham Cell purification
JP7173671B2 (en) * 2018-10-09 2022-11-16 シー テクノロジーズ、インコーポレーテッド Mass control system for chromatography

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090081084A1 (en) * 2003-07-14 2009-03-26 Gjerde Douglas T Low Dead Volume Extraction Column Device
US20100140173A1 (en) * 2004-12-03 2010-06-10 Chris Suh Method and Device for Gravity Flow Chromatography
US20100200509A1 (en) * 2003-07-14 2010-08-12 Chris Suh Method and device for sample preparation
WO2014127314A1 (en) * 2013-02-15 2014-08-21 Phynexus, Inc. Devices and methods for purification of biological cells

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5215927A (en) * 1986-01-30 1993-06-01 Fred Hutchinson Cancer Research Center Method for immunoselection of cells using avidin and biotin
US5773224A (en) * 1996-02-12 1998-06-30 Grandics; Peter Immunoselection system for cell elution
WO1999032886A1 (en) * 1997-12-23 1999-07-01 Vicam, L.P. Generic signalling mechanism for detection of analytes
AU2003291249A1 (en) * 2002-12-18 2004-07-29 Aclara Biosciences, Inc. Multiplexed immunohistochemical assays using molecular tags
US9370732B2 (en) * 2013-02-15 2016-06-21 Douglas T. Gjerde Methods for purifying biological cells
CN106940268B (en) * 2012-02-23 2021-09-21 朱诺治疗有限公司 Chromatographic separation of cells and other complex biological materials
MX2014014065A (en) * 2012-06-27 2015-02-04 Hoffmann La Roche Method for the selection and production of tailor-made, selective and multi-specific therapeutic molecules comprising at least two different targeting entities and uses thereof.

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090081084A1 (en) * 2003-07-14 2009-03-26 Gjerde Douglas T Low Dead Volume Extraction Column Device
US20100200509A1 (en) * 2003-07-14 2010-08-12 Chris Suh Method and device for sample preparation
US20100140173A1 (en) * 2004-12-03 2010-06-10 Chris Suh Method and Device for Gravity Flow Chromatography
WO2014127314A1 (en) * 2013-02-15 2014-08-21 Phynexus, Inc. Devices and methods for purification of biological cells

Also Published As

Publication number Publication date
EP3126027A1 (en) 2017-02-08
GB202102155D0 (en) 2021-03-31
GB201618356D0 (en) 2016-12-14
GB2539857B (en) 2021-03-31
GB2539857A (en) 2016-12-28
WO2015154048A1 (en) 2015-10-08
EP3126027A4 (en) 2017-11-01
GB2587768A (en) 2021-04-07

Similar Documents

Publication Publication Date Title
HK1253095A1 (en) Cell culture device, system and methods of use thereof
HK1250543A1 (en) Methods and devices for multi-step cell purification and concentration
GB2552267B (en) Detection and treatment of disease exhibiting disease cell heterogeneity and systems and methods for communicating test results
EP3239688A4 (en) Chemical substance concentrator and chemical substance detecting device
EP3162392A4 (en) Blood purification device
GB201401773D0 (en) Incubator apparatus and methods
EP3144022A4 (en) Blood purification device
GB201505228D0 (en) Energy concentration device
EP3107996A4 (en) Tscm cells and methods for use
EP3192542A4 (en) Blood purification device
SG11201700274XA (en) Electrochemical detection of microorganisms
GB201515255D0 (en) Devices and methods for purification of biological cells
EP3485927C0 (en) Blood sample treatment using open cell foam
IL251157A0 (en) Impairment detection with biological considerations
SG11201610430QA (en) Growth-independent detection of cells
PL3132020T3 (en) Vessel for cell culture and use thereof
SG11201610514SA (en) Bioreactor and uses thereof
GB201412316D0 (en) Detecting the absence of micro-organisms
IL252123B (en) Device for improving the chemical and physical properties of water and methods of using same
IL247797A0 (en) Glucometer and method for use
SG11201700623YA (en) Biological treatment method and biological treatment device
SG11201607173RA (en) Reactor system and use thereof
GB2539857B (en) Devices and methods for purification, detection and use of biological cells
IL250366B (en) Systems and methods for liquid purification
SG11201607989TA (en) Blood sampling devices and related methods