FI20075278A0 - Novel completely human anti-VAP-1 monoclonal antibodies - Google Patents

Novel completely human anti-VAP-1 monoclonal antibodies

Info

Publication number
FI20075278A0
FI20075278A0 FI20075278A FI20075278A FI20075278A0 FI 20075278 A0 FI20075278 A0 FI 20075278A0 FI 20075278 A FI20075278 A FI 20075278A FI 20075278 A FI20075278 A FI 20075278A FI 20075278 A0 FI20075278 A0 FI 20075278A0
Authority
FI
Finland
Prior art keywords
vap
monoclonal antibodies
human anti
completely human
novel completely
Prior art date
Application number
FI20075278A
Other languages
Finnish (fi)
Swedish (sv)
Inventor
David John Smith
Petri Vainio
Jari Mikkola
Paeivi Vuorio
Jani Vainio
Original Assignee
Biotie Therapies Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biotie Therapies Corp filed Critical Biotie Therapies Corp
Priority to FI20075278A priority Critical patent/FI20075278A0/en
Publication of FI20075278A0 publication Critical patent/FI20075278A0/en
Priority to HUE13190488A priority patent/HUE041656T2/en
Priority to UAA200910613A priority patent/UA97516C2/en
Priority to AU2008240560A priority patent/AU2008240560B2/en
Priority to PT13190488T priority patent/PT2692737T/en
Priority to RS20150427A priority patent/RS54066B1/en
Priority to NZ580194A priority patent/NZ580194A/en
Priority to CA3059580A priority patent/CA3059580C/en
Priority to EP08736848.6A priority patent/EP2164872B1/en
Priority to PCT/FI2008/050199 priority patent/WO2008129124A1/en
Priority to KR1020097021869A priority patent/KR101352416B1/en
Priority to CN2008800209043A priority patent/CN101679523B/en
Priority to PL08736848T priority patent/PL2164872T3/en
Priority to LTEP13190488.0T priority patent/LT2692737T/en
Priority to DK08736848.6T priority patent/DK2164872T3/en
Priority to SI200831444T priority patent/SI2164872T1/en
Priority to DK13190488.0T priority patent/DK2692737T3/en
Priority to EP13190488.0A priority patent/EP2692737B1/en
Priority to CA2683079A priority patent/CA2683079C/en
Priority to CA2962519A priority patent/CA2962519C/en
Priority to RU2009142808/10A priority patent/RU2459832C2/en
Priority to SI200832000T priority patent/SI2692737T1/en
Priority to ES13190488.0T priority patent/ES2690307T3/en
Priority to ES08736848.6T priority patent/ES2540566T3/en
Priority to CA3059600A priority patent/CA3059600C/en
Priority to PL13190488T priority patent/PL2692737T3/en
Priority to JP2010503537A priority patent/JP5728225B2/en
Priority to PT87368486T priority patent/PT2164872E/en
Priority to CA3059571A priority patent/CA3059571C/en
Priority to US12/081,707 priority patent/US7897149B2/en
Priority to ZA200907220A priority patent/ZA200907220B/en
Priority to IL201601A priority patent/IL201601A/en
Priority to HK10107584.5A priority patent/HK1141039A1/en
Priority to US12/940,476 priority patent/US8142783B2/en
Priority to HRP20150615TT priority patent/HRP20150615T1/en
Priority to CY20151100533T priority patent/CY1116413T1/en
Priority to CY181101032T priority patent/CY1121132T1/en
Priority to HRP20181616TT priority patent/HRP20181616T1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Neurology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Diabetes (AREA)
  • Neurosurgery (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pulmonology (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Cardiology (AREA)
  • Physics & Mathematics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Plant Pathology (AREA)
  • Dermatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
FI20075278A 2007-04-20 2007-04-20 Novel completely human anti-VAP-1 monoclonal antibodies FI20075278A0 (en)

Priority Applications (38)

Application Number Priority Date Filing Date Title
FI20075278A FI20075278A0 (en) 2007-04-20 2007-04-20 Novel completely human anti-VAP-1 monoclonal antibodies
RU2009142808/10A RU2459832C2 (en) 2007-04-20 2008-04-17 New completely human vap-1 monoclonal antibodies
CA2683079A CA2683079C (en) 2007-04-20 2008-04-17 Novel fully human anti-vap-1 monoclonal antibodies
CA3059571A CA3059571C (en) 2007-04-20 2008-04-17 Novel fully human anti-vap-1 monoclonal antibodies
AU2008240560A AU2008240560B2 (en) 2007-04-20 2008-04-17 Novel fully human anti-VAP-1 monoclonal antibodies
CA2962519A CA2962519C (en) 2007-04-20 2008-04-17 Novel fully human anti-vap-1 monoclonal antibodies
RS20150427A RS54066B1 (en) 2007-04-20 2008-04-17 Fully human anti-vap-1 monoclonal antibodies
NZ580194A NZ580194A (en) 2007-04-20 2008-04-17 Novel fully human anti-vap-1 monoclonal antibodies
CA3059580A CA3059580C (en) 2007-04-20 2008-04-17 Novel fully human anti-vap-1 monoclonal antibodies
EP08736848.6A EP2164872B1 (en) 2007-04-20 2008-04-17 Fully human anti-vap-1 monoclonal antibodies
PCT/FI2008/050199 WO2008129124A1 (en) 2007-04-20 2008-04-17 Novel fully human anti-vap-1 monoclonal antibodies
KR1020097021869A KR101352416B1 (en) 2007-04-20 2008-04-17 Novel fully human anti-VAP-1 monoclonal antibodies
CN2008800209043A CN101679523B (en) 2007-04-20 2008-04-17 Novel fully human anti-vap-1 monoclonal antibodies
PL08736848T PL2164872T3 (en) 2007-04-20 2008-04-17 Fully human anti-vap-1 monoclonal antibodies
LTEP13190488.0T LT2692737T (en) 2007-04-20 2008-04-17 Fully human anti-VAP-1 monoclonal antibodies
DK08736848.6T DK2164872T3 (en) 2007-04-20 2008-04-17 COMPLETE human anti-VAP-1 MONOCLONAL ANTIBODIES
SI200831444T SI2164872T1 (en) 2007-04-20 2008-04-17 Fully human anti-vap-1 monoclonal antibodies
UAA200910613A UA97516C2 (en) 2007-04-20 2008-04-17 Fully human anti-vap-1 monoclonal antibody
EP13190488.0A EP2692737B1 (en) 2007-04-20 2008-04-17 Fully human anti-VAP-1 monoclonal antibodies
HUE13190488A HUE041656T2 (en) 2007-04-20 2008-04-17 Fully human anti-VAP-1 monoclonal antibodies
PT13190488T PT2692737T (en) 2007-04-20 2008-04-17 Fully human anti-vap-1 monoclonal antibodies
DK13190488.0T DK2692737T3 (en) 2007-04-20 2008-04-17 Fully human anti-VAP-1 monoclonal antibodies
ES13190488.0T ES2690307T3 (en) 2007-04-20 2008-04-17 Fully human anti-VAP-1 monoclonal antibodies
SI200832000T SI2692737T1 (en) 2007-04-20 2008-04-17 Fully human anti-VAP-1 monoclonal antibodies
ES08736848.6T ES2540566T3 (en) 2007-04-20 2008-04-17 Fully human anti-VAP-1 monoclonal antibodies
CA3059600A CA3059600C (en) 2007-04-20 2008-04-17 Novel fully human anti-vap-1 monoclonal antibodies
PL13190488T PL2692737T3 (en) 2007-04-20 2008-04-17 Fully human anti-VAP-1 monoclonal antibodies
JP2010503537A JP5728225B2 (en) 2007-04-20 2008-04-17 Fully human anti-VAP-1 antibody, VAP-1 binding fragment, nucleic acid molecule, expression vector, host cell, and pharmaceutical composition
PT87368486T PT2164872E (en) 2007-04-20 2008-04-17 Fully human anti-vap-1 monoclonal antibodies
US12/081,707 US7897149B2 (en) 2007-04-20 2008-04-18 Fully human anti-VAP-1 monoclonal antibodies
ZA200907220A ZA200907220B (en) 2007-04-20 2009-10-15 Novel fully human anti-VAP-1 monoclonal antibodies
IL201601A IL201601A (en) 2007-04-20 2009-10-18 Fully human anti-vap-1 monoclonal antibodies
HK10107584.5A HK1141039A1 (en) 2007-04-20 2010-08-09 Fully human anti-vap-1 monoclonal antibodies vap-1
US12/940,476 US8142783B2 (en) 2007-04-20 2010-11-05 Methods of treating an inflammatory condition involving VAP-1-mediated adhesion with VAP-1-specific antibodies
HRP20150615TT HRP20150615T1 (en) 2007-04-20 2015-06-08 Fully human anti-vap-1 monoclonal antibodies
CY20151100533T CY1116413T1 (en) 2007-04-20 2015-06-23 ANNOUNCED FULLY-HUMAN MONOCLONIC ANTI-VAP-1
CY181101032T CY1121132T1 (en) 2007-04-20 2018-10-05 FULLY-HUMAN MONOCLONE ANTIBODIES ANTI-vap-1
HRP20181616TT HRP20181616T1 (en) 2007-04-20 2018-10-05 Fully human anti-vap-1 monoclonal antibodies

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FI20075278A FI20075278A0 (en) 2007-04-20 2007-04-20 Novel completely human anti-VAP-1 monoclonal antibodies

Publications (1)

Publication Number Publication Date
FI20075278A0 true FI20075278A0 (en) 2007-04-20

Family

ID=38009931

Family Applications (1)

Application Number Title Priority Date Filing Date
FI20075278A FI20075278A0 (en) 2007-04-20 2007-04-20 Novel completely human anti-VAP-1 monoclonal antibodies

Country Status (25)

Country Link
US (2) US7897149B2 (en)
EP (2) EP2164872B1 (en)
JP (1) JP5728225B2 (en)
KR (1) KR101352416B1 (en)
CN (1) CN101679523B (en)
AU (1) AU2008240560B2 (en)
CA (5) CA3059600C (en)
CY (2) CY1116413T1 (en)
DK (2) DK2692737T3 (en)
ES (2) ES2690307T3 (en)
FI (1) FI20075278A0 (en)
HK (1) HK1141039A1 (en)
HR (2) HRP20150615T1 (en)
HU (1) HUE041656T2 (en)
IL (1) IL201601A (en)
LT (1) LT2692737T (en)
NZ (1) NZ580194A (en)
PL (2) PL2164872T3 (en)
PT (2) PT2164872E (en)
RS (1) RS54066B1 (en)
RU (1) RU2459832C2 (en)
SI (2) SI2692737T1 (en)
UA (1) UA97516C2 (en)
WO (1) WO2008129124A1 (en)
ZA (1) ZA200907220B (en)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI20075278A0 (en) * 2007-04-20 2007-04-20 Biotie Therapies Corp Novel completely human anti-VAP-1 monoclonal antibodies
CN102459338A (en) * 2009-05-08 2012-05-16 霍夫曼-拉罗奇有限公司 Humanized anti-egfl7 antibodies and methods using same
UA112154C2 (en) * 2009-09-08 2016-08-10 Біоті Терапіс Корп. Use of vap-1 inhibitors for treating fibrotic conditions
TWI594764B (en) * 2010-04-12 2017-08-11 生化治療公司 Therapeutic use
ES2702246T3 (en) * 2012-03-26 2019-02-28 Sanofi Sa Stable IgG4 binding agent formulations
US9592289B2 (en) 2012-03-26 2017-03-14 Sanofi Stable IgG4 based binding agent formulations
PL3387898T3 (en) * 2013-03-15 2020-10-19 Mayo Foundation For Medical Education And Research Identification and monitoring of monoclonal immunoglobulins by molecular mass
AU2014279863A1 (en) 2013-06-12 2016-01-28 Proximagen Limited New therapeutic uses of enzyme inhibitors
BR112016023046A8 (en) 2014-04-04 2021-05-11 Mayo Found Medical Education & Res kit comprising antibodies and reducing agents
WO2015189534A1 (en) 2014-06-12 2015-12-17 Proximagen Limited Vap-1 inhibitors for treating muscular dystrophy
US10690676B2 (en) 2014-07-29 2020-06-23 Mayo Roundation for Medical Education and Research Quantifying monoclonal antibody therapeutics by LC-MS/MS
CN104628853B (en) * 2015-02-06 2017-10-10 中国人民解放军南京军区军事医学研究所 The anti-anthrax protective antigen PA in people source IgG antibody and its application
US11209439B2 (en) 2015-09-24 2021-12-28 Mayo Foundation For Medical Education And Research Identification of immunoglobulin free light chains by mass spectrometry
AU2016366635A1 (en) 2015-12-07 2018-06-21 Benevolentai Cambridge Limited VAP-1 inhibitors for treating pain
US11161902B2 (en) 2016-05-09 2021-11-02 Helmholtz Zentrum Muenchen—Deutsches Forschungszentrum Fuer Gesundheit Und Umwelt (Gmbh) Tissue-specific exosomes as biomarkers
US10955420B2 (en) 2016-09-07 2021-03-23 Mayo Foundation For Medical Education And Research Identification and monitoring of cleaved immunoglobulins by molecular mass
EP3618865A4 (en) * 2017-05-05 2021-05-05 Vaccinex, Inc. Human anti-semaphorin 4d antibody
EP3681528A4 (en) 2017-09-13 2021-07-21 Mayo Foundation for Medical Education and Research Identification and monitoring of apoptosis inhibitor of macrophage
SG11202003479TA (en) * 2017-10-18 2020-05-28 Regenxbio Inc Fully-human post-translationally modified antibody therapeutics
CN111537740B (en) * 2020-05-22 2021-11-23 长春生物制品研究所有限责任公司 Forest encephalitis virus IgM antibody detection kit and application thereof

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3101690B2 (en) 1987-03-18 2000-10-23 エス・ビィ・２・インコーポレイテッド Modifications of or for denatured antibodies
US5476996A (en) 1988-06-14 1995-12-19 Lidak Pharmaceuticals Human immune system in non-human animal
GB8823869D0 (en) 1988-10-12 1988-11-16 Medical Res Council Production of antibodies
US6300129B1 (en) 1990-08-29 2001-10-09 Genpharm International Transgenic non-human animals for producing heterologous antibodies
US5814318A (en) 1990-08-29 1998-09-29 Genpharm International Inc. Transgenic non-human animals for producing heterologous antibodies
US5770429A (en) 1990-08-29 1998-06-23 Genpharm International, Inc. Transgenic non-human animals capable of producing heterologous antibodies
US5877397A (en) 1990-08-29 1999-03-02 Genpharm International Inc. Transgenic non-human animals capable of producing heterologous antibodies of various isotypes
ES2108048T3 (en) 1990-08-29 1997-12-16 Genpharm Int PRODUCTION AND USE OF LOWER TRANSGENIC ANIMALS CAPABLE OF PRODUCING HETEROLOGICAL ANTIBODIES.
US5625126A (en) 1990-08-29 1997-04-29 Genpharm International, Inc. Transgenic non-human animals for producing heterologous antibodies
US5874299A (en) 1990-08-29 1999-02-23 Genpharm International, Inc. Transgenic non-human animals capable of producing heterologous antibodies
US6255458B1 (en) 1990-08-29 2001-07-03 Genpharm International High affinity human antibodies and human antibodies against digoxin
US5545806A (en) 1990-08-29 1996-08-13 Genpharm International, Inc. Ransgenic non-human animals for producing heterologous antibodies
US5789650A (en) 1990-08-29 1998-08-04 Genpharm International, Inc. Transgenic non-human animals for producing heterologous antibodies
US5661016A (en) 1990-08-29 1997-08-26 Genpharm International Inc. Transgenic non-human animals capable of producing heterologous antibodies of various isotypes
US5633425A (en) 1990-08-29 1997-05-27 Genpharm International, Inc. Transgenic non-human animals capable of producing heterologous antibodies
EP0746609A4 (en) 1991-12-17 1997-12-17 Genpharm Int Transgenic non-human animals capable of producing heterologous antibodies
US5580780A (en) 1992-06-09 1996-12-03 Jalkanen; Sirpa Vascular adhesion protein-(VAP-1) and VAP-1-specific antibodies
NZ299958A (en) * 1992-06-09 2000-07-28 Marko Salmi Antagonising endothelial vascular adhesion protein-1 (VAP-1) mediated binding of endothelial cells to lymphocytes using anti-VAP-1-antibodiess
JPH08509612A (en) 1993-04-26 1996-10-15 ジェンファーム インターナショナル インコーポレイテッド Transgenic non-human animal capable of producing heterologous antibody
WO1998053049A1 (en) * 1997-05-23 1998-11-26 Biotie Therapies Ltd. Vascular adhesion protein-1 having amine oxidase activity
NZ517202A (en) 1999-08-24 2004-05-28 Medarex Inc Human CTLA-4 antibodies and their uses
CA2481334A1 (en) * 2002-04-01 2003-10-16 Anthony C. Stevens Tissue-specific endothelial membrane proteins
FI20020807A0 (en) * 2002-04-29 2002-04-29 Biotie Therapies Oyj Novel humanized anti-VAP-1 monoclonal antibodies
FI20075278A0 (en) * 2007-04-20 2007-04-20 Biotie Therapies Corp Novel completely human anti-VAP-1 monoclonal antibodies

Also Published As

Publication number Publication date
KR101352416B1 (en) 2014-01-17
KR20100021562A (en) 2010-02-25
CY1116413T1 (en) 2017-02-08
US8142783B2 (en) 2012-03-27
HRP20150615T1 (en) 2015-07-03
US20110117021A1 (en) 2011-05-19
AU2008240560B2 (en) 2012-05-17
LT2692737T (en) 2018-10-25
CA2962519C (en) 2019-12-31
DK2692737T3 (en) 2018-10-29
ES2540566T3 (en) 2015-07-10
CA3059600C (en) 2020-06-30
EP2164872A1 (en) 2010-03-24
DK2164872T3 (en) 2015-06-29
RU2459832C2 (en) 2012-08-27
AU2008240560A1 (en) 2008-10-30
PT2164872E (en) 2015-07-30
CA2683079A1 (en) 2008-10-30
SI2692737T1 (en) 2019-04-30
CA2962519A1 (en) 2008-10-30
WO2008129124A1 (en) 2008-10-30
UA97516C2 (en) 2012-02-27
ES2690307T3 (en) 2018-11-20
CA3059571C (en) 2020-06-30
NZ580194A (en) 2011-09-30
CA3059571A1 (en) 2008-10-30
PT2692737T (en) 2018-10-25
JP5728225B2 (en) 2015-06-03
CA2683079C (en) 2017-04-11
PL2164872T3 (en) 2015-08-31
EP2692737B1 (en) 2018-07-25
CA3059600A1 (en) 2008-10-30
CA3059580C (en) 2020-06-30
HK1141039A1 (en) 2010-10-29
CN101679523A (en) 2010-03-24
SI2164872T1 (en) 2015-07-31
ZA200907220B (en) 2010-07-28
JP2010524449A (en) 2010-07-22
RU2009142808A (en) 2011-05-27
US7897149B2 (en) 2011-03-01
US20090081126A1 (en) 2009-03-26
CY1121132T1 (en) 2019-12-11
EP2692737A1 (en) 2014-02-05
IL201601A (en) 2015-06-30
HUE041656T2 (en) 2019-05-28
PL2692737T3 (en) 2019-07-31
EP2164872A4 (en) 2011-01-12
CN101679523B (en) 2013-11-06
IL201601A0 (en) 2010-05-31
RS54066B1 (en) 2015-10-30
EP2164872B1 (en) 2015-05-27
CA3059580A1 (en) 2008-10-30
HRP20181616T1 (en) 2018-12-14

Similar Documents

Publication Publication Date Title
CY2019004I1 (en) MODIFIED ANTI-IL-23P19 ANTIBODIES
FI20075278A0 (en) Novel completely human anti-VAP-1 monoclonal antibodies
LTPA2018017I1 (en) Human CGRP receptor binding antibodies
DK2131860T3 (en) ANTI-sclerostin ANTIBODIES
SMT201700083B (en) MONOCLONAL ANTIBODIES
BRPI0907532A2 (en) Humanized anti-c5ar antibodies
BRPI0809677A2 (en) Anti-GSE Antibodies
NO344963B1 (en) Humanized antibody
DK2066695T3 (en) ANTI-myostatin ANTIBODIES
BRPI0821777A2 (en) Bivalent bispecific antibodies
BRPI0819165A2 (en) Anti-vegf Antibodies
BRPI0923359A2 (en) Anti-igf Antibodies
BRPI0906877A2 (en) Improved anti-trkb antibodies
BRPI0814003A2 (en) ANTIBODY FORMULATIONS
BRPI0814252A2 (en) Antibody Formulations
BRPI0817273A2 (en) Modified antibody constant region
BRPI0819210A2 (en) Anti-rsv G Protein Antibodies
BRPI0907237A2 (en) Anti-cldn6 antibody
ATE483732T1 (en) MADCAM ANTIBODIES
DK2292663T3 (en) Antagonistic human-light specific human monoclonal antibodies
BRPI0814111A2 (en) CYTOTOXIC MONOCLONAL ANTIBODY
BRPI0815567A2 (en) V-INTEGRINE ANTIALFA HYBRID ANTIBODIES DESIGNED
BRPI0807991A2 (en) PREPARED ANTI-IL-23R ANTIBODIES.
IL200168A0 (en) Monoclonal anti-cxcl13 antibodies
BRPI0817427A2 (en) Anti-bst2 antibody