ES392014A1 - Procedure for the preparation of the 6 deoxy-5-oxitetraciclina esteres. (Machine-translation by Google Translate, not legally binding) - Google Patents
Procedure for the preparation of the 6 deoxy-5-oxitetraciclina esteres. (Machine-translation by Google Translate, not legally binding)Info
- Publication number
- ES392014A1 ES392014A1 ES392014A ES392014A ES392014A1 ES 392014 A1 ES392014 A1 ES 392014A1 ES 392014 A ES392014 A ES 392014A ES 392014 A ES392014 A ES 392014A ES 392014 A1 ES392014 A1 ES 392014A1
- Authority
- ES
- Spain
- Prior art keywords
- deoxy
- translation
- procedure
- hydrogen
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/65—Tetracyclines
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Procedure for the preparation of the esters of 6-deoxy-5-oxytetracycline and their addition salts with pharmaceutically acceptable non-toxic acids, of the structure: ** (See formula) ** where R is a radical of a monocarboxylic or dicarboxylic organic acid with 1 to 10 carbon atoms and X is hydrogen, chlorine or bromine, characterized by reacting a compound taken from the group consisting of ** (See formula) ** (where R and X have the same meaning as before), and its acid addition salts, with hydrogen, in the presence of an appropriate catalyst from the platinum group, at a temperature of 0º to 50ºC and pressure between the atmosphere and 100 atmospheres, until 1 to 3 moles of hydrogen have been absorbed by mol of tetracycline compound, by isolating the mixture of alpha-6 epimer and beta-6 epimer thus formed and purified as is or separated into its components by the usual techniques. (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT2587570 | 1970-06-12 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES392014A1 true ES392014A1 (en) | 1973-08-01 |
Family
ID=11217998
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES392014A Expired ES392014A1 (en) | 1970-06-12 | 1971-06-07 | Procedure for the preparation of the 6 deoxy-5-oxitetraciclina esteres. (Machine-translation by Google Translate, not legally binding) |
Country Status (17)
| Country | Link |
|---|---|
| JP (1) | JPS5233115B1 (en) |
| AT (1) | AT305494B (en) |
| AU (1) | AU2940371A (en) |
| BE (1) | BE768381A (en) |
| CA (1) | CA969930A (en) |
| CS (1) | CS154691B2 (en) |
| DE (1) | DE2128432A1 (en) |
| ES (1) | ES392014A1 (en) |
| FR (1) | FR2100752B1 (en) |
| GB (1) | GB1288905A (en) |
| HU (1) | HU162872B (en) |
| IE (1) | IE35338B1 (en) |
| IL (1) | IL37003A (en) |
| NL (1) | NL7107555A (en) |
| SE (1) | SE360354B (en) |
| SU (1) | SU430545A3 (en) |
| ZA (1) | ZA713734B (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK386784A (en) * | 1983-08-17 | 1985-02-18 | Hovione Int Ltd | PROCEDURE FOR PREPARING ALFA-6-DESOXY-TETRACYCLINES |
-
1971
- 1971-05-28 AU AU29403/71A patent/AU2940371A/en not_active Expired
- 1971-06-02 NL NL7107555A patent/NL7107555A/xx unknown
- 1971-06-07 ES ES392014A patent/ES392014A1/en not_active Expired
- 1971-06-07 GB GB1288905D patent/GB1288905A/en not_active Expired
- 1971-06-07 FR FR7120502A patent/FR2100752B1/fr not_active Expired
- 1971-06-07 SU SU1659762A patent/SU430545A3/en active
- 1971-06-07 CS CS714149A patent/CS154691B2/en unknown
- 1971-06-08 IE IE729/71A patent/IE35338B1/en unknown
- 1971-06-08 DE DE19712128432 patent/DE2128432A1/en active Pending
- 1971-06-08 IL IL37003A patent/IL37003A/en unknown
- 1971-06-08 CA CA115,057A patent/CA969930A/en not_active Expired
- 1971-06-08 JP JP46039923A patent/JPS5233115B1/ja active Pending
- 1971-06-09 ZA ZA713734A patent/ZA713734B/en unknown
- 1971-06-09 AT AT4982/71A patent/AT305494B/en not_active IP Right Cessation
- 1971-06-10 SE SE07525/71A patent/SE360354B/xx unknown
- 1971-06-11 HU HUSO1006A patent/HU162872B/hu unknown
- 1971-06-11 BE BE768381A patent/BE768381A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IL37003A (en) | 1974-12-31 |
| DE2128432A1 (en) | 1971-12-16 |
| CA969930A (en) | 1975-06-24 |
| ZA713734B (en) | 1972-01-26 |
| HU162872B (en) | 1973-04-28 |
| IL37003A0 (en) | 1971-08-25 |
| CS154691B2 (en) | 1974-04-30 |
| IE35338L (en) | 1971-12-12 |
| AU2940371A (en) | 1972-11-30 |
| AT305494B (en) | 1973-01-15 |
| NL7107555A (en) | 1971-12-14 |
| JPS5233115B1 (en) | 1977-08-26 |
| SU430545A3 (en) | 1974-05-30 |
| BE768381A (en) | 1971-12-13 |
| FR2100752A1 (en) | 1972-03-24 |
| IE35338B1 (en) | 1976-01-21 |
| GB1288905A (en) | 1972-09-13 |
| FR2100752B1 (en) | 1975-01-17 |
| SE360354B (en) | 1973-09-24 |
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