EP3268496A4 - Graphene fet devices, systems, and methods of using the same for sequencing nucleic acids - Google Patents

Graphene fet devices, systems, and methods of using the same for sequencing nucleic acids Download PDF

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Publication number
EP3268496A4
EP3268496A4 EP16762454.3A EP16762454A EP3268496A4 EP 3268496 A4 EP3268496 A4 EP 3268496A4 EP 16762454 A EP16762454 A EP 16762454A EP 3268496 A4 EP3268496 A4 EP 3268496A4
Authority
EP
European Patent Office
Prior art keywords
systems
methods
nucleic acids
same
fet devices
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP16762454.3A
Other languages
German (de)
French (fr)
Other versions
EP3268496A1 (en
Inventor
Paul Hoffman
Mitchell LERNER
Pieter ROOYEN van
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AGILOME, INC.
Original Assignee
Agilome Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Agilome Inc filed Critical Agilome Inc
Publication of EP3268496A1 publication Critical patent/EP3268496A1/en
Publication of EP3268496A4 publication Critical patent/EP3268496A4/en
Withdrawn legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
    • C12Q1/6874—Methods for sequencing involving nucleic acid arrays, e.g. sequencing by hybridisation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/403—Cells and electrode assemblies
    • G01N27/414—Ion-sensitive or chemical field-effect transistors, i.e. ISFETS or CHEMFETS
    • G01N27/4146—Ion-sensitive or chemical field-effect transistors, i.e. ISFETS or CHEMFETS involving nanosized elements, e.g. nanotubes, nanowires
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y30/00—Nanotechnology for materials or surface science, e.g. nanocomposites

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microelectronics & Electronic Packaging (AREA)
  • Nanotechnology (AREA)
  • Pathology (AREA)
  • Electrochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
EP16762454.3A 2015-03-09 2016-03-09 Graphene fet devices, systems, and methods of using the same for sequencing nucleic acids Withdrawn EP3268496A4 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201562130598P 2015-03-09 2015-03-09
US201562130601P 2015-03-09 2015-03-09
US201562130594P 2015-03-09 2015-03-09
US201562130621P 2015-03-10 2015-03-10
PCT/US2016/021606 WO2016145110A1 (en) 2015-03-09 2016-03-09 Graphene fet devices, systems, and methods of using the same for sequencing nucleic acids

Publications (2)

Publication Number Publication Date
EP3268496A1 EP3268496A1 (en) 2018-01-17
EP3268496A4 true EP3268496A4 (en) 2018-09-05

Family

ID=56879360

Family Applications (1)

Application Number Title Priority Date Filing Date
EP16762454.3A Withdrawn EP3268496A4 (en) 2015-03-09 2016-03-09 Graphene fet devices, systems, and methods of using the same for sequencing nucleic acids

Country Status (2)

Country Link
EP (1) EP3268496A4 (en)
WO (1) WO2016145110A1 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9618474B2 (en) 2014-12-18 2017-04-11 Edico Genome, Inc. Graphene FET devices, systems, and methods of using the same for sequencing nucleic acids
US11782057B2 (en) 2014-12-18 2023-10-10 Cardea Bio, Inc. Ic with graphene fet sensor array patterned in layers above circuitry formed in a silicon based cmos wafer
US10006910B2 (en) 2014-12-18 2018-06-26 Agilome, Inc. Chemically-sensitive field effect transistors, systems, and methods for manufacturing and using the same
US11921112B2 (en) 2014-12-18 2024-03-05 Paragraf Usa Inc. Chemically-sensitive field effect transistors, systems, and methods for manufacturing and using the same
WO2017201081A1 (en) * 2016-05-16 2017-11-23 Agilome, Inc. Graphene fet devices, systems, and methods of using the same for sequencing nucleic acids
US11905552B2 (en) 2017-08-04 2024-02-20 Keck Graduate Institute Of Applied Life Sciences Immobilized RNPs for sequence-specific nucleic acid capture and digital detection
CN114371208A (en) * 2021-11-30 2022-04-19 山东师范大学 Biosensor manufacturing and detecting method, biosensor and photo-electromagnetic system

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110210314A1 (en) * 2010-02-26 2011-09-01 Samsung Electronics Co., Ltd. Graphene electronic device and method of fabricating the same
US20120214172A1 (en) * 2011-02-18 2012-08-23 Uwm Research Foundation, Inc. Graphene-based field-effect transistor biosensors
US20120220053A1 (en) * 2011-02-17 2012-08-30 Rutgers, The State University Of New Jersey Graphene-encapsulated nanoparticle-based biosensor for the selective detection of biomarkers
US20120286244A1 (en) * 2011-05-10 2012-11-15 International Business Machines Corporation Carbon field effect transistors having charged monolayers to reduce parasitic resistance
WO2014112199A1 (en) * 2013-01-17 2014-07-24 株式会社日立ハイテクノロジーズ Biomolecule measuring device
WO2014176524A2 (en) * 2013-04-25 2014-10-30 The Trustees Of The University Of Pennsylvania Opioid detection based on high quality graphene transistor arrays and a synthetic mu receptor
EP3235010A1 (en) * 2014-12-18 2017-10-25 Agilome, Inc. Chemically-sensitive field effect transistor

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103168341B (en) * 2010-07-03 2016-10-05 生命科技公司 There is the chemosensitive sensor of lightly doped discharger
US8962366B2 (en) * 2013-01-28 2015-02-24 Life Technologies Corporation Self-aligned well structures for low-noise chemical sensors

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110210314A1 (en) * 2010-02-26 2011-09-01 Samsung Electronics Co., Ltd. Graphene electronic device and method of fabricating the same
US20120220053A1 (en) * 2011-02-17 2012-08-30 Rutgers, The State University Of New Jersey Graphene-encapsulated nanoparticle-based biosensor for the selective detection of biomarkers
US20120214172A1 (en) * 2011-02-18 2012-08-23 Uwm Research Foundation, Inc. Graphene-based field-effect transistor biosensors
US20120286244A1 (en) * 2011-05-10 2012-11-15 International Business Machines Corporation Carbon field effect transistors having charged monolayers to reduce parasitic resistance
WO2014112199A1 (en) * 2013-01-17 2014-07-24 株式会社日立ハイテクノロジーズ Biomolecule measuring device
EP2947453A1 (en) * 2013-01-17 2015-11-25 Hitachi High-Technologies Corporation Biomolecule measuring device
WO2014176524A2 (en) * 2013-04-25 2014-10-30 The Trustees Of The University Of Pennsylvania Opioid detection based on high quality graphene transistor arrays and a synthetic mu receptor
EP3235010A1 (en) * 2014-12-18 2017-10-25 Agilome, Inc. Chemically-sensitive field effect transistor

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO2016145110A1 *

Also Published As

Publication number Publication date
WO2016145110A1 (en) 2016-09-15
EP3268496A1 (en) 2018-01-17

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RIN1 Information on inventor provided before grant (corrected)

Inventor name: HOFFMAN, PAUL

Inventor name: LERNER, MITCHELL

Inventor name: ROOYEN VAN, PIETER

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