EP2776051A4 - Therapeutic combinations and methods of treating melanoma - Google Patents
Therapeutic combinations and methods of treating melanomaInfo
- Publication number
- EP2776051A4 EP2776051A4 EP12842985.9A EP12842985A EP2776051A4 EP 2776051 A4 EP2776051 A4 EP 2776051A4 EP 12842985 A EP12842985 A EP 12842985A EP 2776051 A4 EP2776051 A4 EP 2776051A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- methods
- therapeutic combinations
- treating melanoma
- melanoma
- treating
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2869—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against hormone receptors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- C07K16/3053—Skin, nerves, brain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Neurology (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Cell Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Oncology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Endocrinology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201161552893P | 2011-10-28 | 2011-10-28 | |
US201261678978P | 2012-08-02 | 2012-08-02 | |
PCT/US2012/061533 WO2013063001A1 (en) | 2011-10-28 | 2012-10-24 | Therapeutic combinations and methods of treating melanoma |
Publications (2)
Publication Number | Publication Date |
---|---|
EP2776051A1 EP2776051A1 (en) | 2014-09-17 |
EP2776051A4 true EP2776051A4 (en) | 2015-06-17 |
Family
ID=48168400
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP12842985.9A Withdrawn EP2776051A4 (en) | 2011-10-28 | 2012-10-24 | Therapeutic combinations and methods of treating melanoma |
Country Status (18)
Country | Link |
---|---|
EP (1) | EP2776051A4 (en) |
JP (2) | JP6251682B2 (en) |
KR (1) | KR20140097205A (en) |
CN (1) | CN104039340B (en) |
AR (1) | AR088509A1 (en) |
AU (1) | AU2012328980A1 (en) |
BR (1) | BR112014009953A2 (en) |
CA (1) | CA2850034A1 (en) |
CL (1) | CL2014001092A1 (en) |
CO (1) | CO7151543A2 (en) |
EA (1) | EA201490879A1 (en) |
IL (1) | IL232135A0 (en) |
IN (1) | IN2014CN03062A (en) |
MX (1) | MX2014004991A (en) |
PE (1) | PE20142312A1 (en) |
SG (1) | SG11201401815XA (en) |
TW (1) | TW201325613A (en) |
WO (1) | WO2013063001A1 (en) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2708669T3 (en) | 2011-08-01 | 2019-04-10 | Hoffmann La Roche | Cancer treatment procedures using PD-1 axis-binding antagonists and MEK inhibitors |
US9216170B2 (en) | 2012-03-19 | 2015-12-22 | Hoffmann-La Roche Inc. | Combination therapy for proliferative disorders |
EP3169361B1 (en) | 2014-07-15 | 2019-06-19 | F.Hoffmann-La Roche Ag | Compositions for treating cancer using pd-1 axis binding antagonists and mek inhibitors |
JP6784668B2 (en) * | 2014-10-10 | 2020-11-11 | ファイザー・インク | Synergistic auristatin combination |
CN108025035B (en) * | 2015-08-03 | 2023-06-13 | Enb治疗公司 | Compositions and methods for treating cancers associated with ETBR activation |
FR3053042B1 (en) * | 2016-06-24 | 2018-08-10 | Commissariat A L'energie Atomique Et Aux Energies Alternatives | ANTIBODIES AGAINST ENDOTHELIN RECEPTOR B SUBTYPE B AND USES THEREOF |
CA3049926A1 (en) | 2017-01-17 | 2018-07-26 | Heparegenix Gmbh | Protein kinase inhibitors for promoting liver regeneration or reducing or preventing hepatocyte death |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20110086837A1 (en) * | 2009-10-12 | 2011-04-14 | Genentech, Inc. | Combinations of a pi3k inhibitor and a mek inhibitor |
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MX2014004991A (en) | 2014-05-22 |
JP2014532648A (en) | 2014-12-08 |
BR112014009953A2 (en) | 2017-12-05 |
CO7151543A2 (en) | 2014-12-29 |
IN2014CN03062A (en) | 2015-07-31 |
TW201325613A (en) | 2013-07-01 |
CN104039340B (en) | 2017-04-05 |
IL232135A0 (en) | 2014-05-28 |
SG11201401815XA (en) | 2014-05-29 |
PE20142312A1 (en) | 2015-01-25 |
JP6251682B2 (en) | 2017-12-20 |
CA2850034A1 (en) | 2013-05-02 |
JP2018027948A (en) | 2018-02-22 |
CN104039340A (en) | 2014-09-10 |
KR20140097205A (en) | 2014-08-06 |
EP2776051A1 (en) | 2014-09-17 |
EA201490879A1 (en) | 2014-08-29 |
WO2013063001A1 (en) | 2013-05-02 |
AR088509A1 (en) | 2014-06-11 |
AU2012328980A1 (en) | 2014-04-24 |
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