EP0760012A4 - Method of detecting compounds utilizing genetically modified lambdoid bacteriophage - Google Patents

Method of detecting compounds utilizing genetically modified lambdoid bacteriophage

Info

Publication number
EP0760012A4
EP0760012A4 EP94920140A EP94920140A EP0760012A4 EP 0760012 A4 EP0760012 A4 EP 0760012A4 EP 94920140 A EP94920140 A EP 94920140A EP 94920140 A EP94920140 A EP 94920140A EP 0760012 A4 EP0760012 A4 EP 0760012A4
Authority
EP
European Patent Office
Prior art keywords
genetically modified
detecting compounds
compounds utilizing
lambdoid bacteriophage
utilizing genetically
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP94920140A
Other languages
German (de)
French (fr)
Other versions
EP0760012A1 (en
Inventor
Bryan L Ray
Edmund C C Lin
Roberto Crea
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Symbiotech Inc
Original Assignee
Symbiotech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Symbiotech Inc filed Critical Symbiotech Inc
Publication of EP0760012A1 publication Critical patent/EP0760012A1/en
Publication of EP0760012A4 publication Critical patent/EP0760012A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures
    • C40B40/02—Libraries contained in or displayed by microorganisms, e.g. bacteria or animal cells; Libraries contained in or displayed by vectors, e.g. plasmids; Libraries containing only microorganisms or vectors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1037—Screening libraries presented on the surface of microorganisms, e.g. phage display, E. coli display
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physics & Mathematics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Virology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Plant Pathology (AREA)
  • Food Science & Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cell Biology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
EP94920140A 1994-06-10 1994-06-10 Method of detecting compounds utilizing genetically modified lambdoid bacteriophage Withdrawn EP0760012A4 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1994/006543 WO1995034683A1 (en) 1994-06-10 1994-06-10 Method of detecting compounds utilizing genetically modified lambdoid bacteriophage

Publications (2)

Publication Number Publication Date
EP0760012A1 EP0760012A1 (en) 1997-03-05
EP0760012A4 true EP0760012A4 (en) 1997-07-02

Family

ID=22242658

Family Applications (1)

Application Number Title Priority Date Filing Date
EP94920140A Withdrawn EP0760012A4 (en) 1994-06-10 1994-06-10 Method of detecting compounds utilizing genetically modified lambdoid bacteriophage

Country Status (3)

Country Link
EP (1) EP0760012A4 (en)
AU (1) AU7104294A (en)
WO (1) WO1995034683A1 (en)

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DK0564531T3 (en) * 1990-12-03 1998-09-28 Genentech Inc Enrichment procedure for variant proteins with altered binding properties
EP1100890A2 (en) 1998-07-27 2001-05-23 Genentech, Inc. Improved transformation efficiency in phage display through modification of a coat protein
DE60020366T2 (en) 1999-06-14 2006-02-02 Genentech Inc., San Francisco STRUCTURED PEPTIDE EQUIPMENT FOR EXHIBITING ROTATION LIBRARIES TO PHAGE
US6914123B2 (en) 2001-04-17 2005-07-05 Genentech, Inc. Hairpin peptides with a novel structural motif and methods relating thereto
US20070160576A1 (en) 2001-06-05 2007-07-12 Genentech, Inc. IL-17A/F heterologous polypeptides and therapeutic uses thereof
KR100607612B1 (en) 2001-06-20 2006-08-02 제넨테크, 인크. Compositions and Methods for the Diagnosis and Treatment of Tumor
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EP2067472A1 (en) 2002-01-02 2009-06-10 Genentech, Inc. Compositions and methods for the diagnosis and treatment of tumor
JP2005536190A (en) 2002-04-16 2005-12-02 ジェネンテック・インコーポレーテッド Compositions and methods for tumor diagnosis and treatment
MX341074B (en) 2003-07-08 2016-08-05 Genentech Inc Il-17 a/f heterologous polypeptides and therapeutic uses thereof.
US7329725B1 (en) 2003-10-29 2008-02-12 Nastech Pharmaceutical Company Inc. Phage displayed Trp cage ligands
SI2295073T1 (en) 2003-11-17 2014-07-31 Genentech, Inc. Antibody against CD22 for the treatment of tumour of hematopoietic origin
MX2007010922A (en) 2005-03-10 2007-10-12 Genentech Inc Methods and compositions for modulating vascular integrity.
EP2007428A2 (en) 2006-04-05 2008-12-31 Genentech, Inc. Method for using boc/cdo to modulate hedgehog signaling
EP2520935A3 (en) 2006-08-09 2013-02-13 Homestead Clinical Corporation Organ-specific proteins and methods of their use
WO2008032833A1 (en) 2006-09-14 2008-03-20 Medical & Biological Laboratories Co., Ltd. Antibody having enhanced adcc activity and method for production thereof
DK2436781T3 (en) 2007-02-22 2016-01-11 Genentech Inc Methods for the detection of inflammatory bowel disease
CA2728473A1 (en) 2008-06-20 2009-12-23 National University Corporation Okayama University Antibody against oxidized ldl/.beta.2gpi complex and use of the same
US9182406B2 (en) 2008-08-04 2015-11-10 Biodesy, Inc. Nonlinear optical detection of molecules comprising an unnatural amino acid possessing a hyperpolarizability
KR101151805B1 (en) 2008-10-20 2012-06-01 광주과학기술원 Bipodal Peptide Binder
JP5885664B2 (en) 2009-09-25 2016-03-15 ゾーマ テクノロジー リミテッド Screening method
US8697386B2 (en) 2009-10-22 2014-04-15 Genentech, Inc. Methods and compositions for modulating hepsin activation of macrophage-stimulating protein
TWI537383B (en) 2009-11-30 2016-06-11 建南德克公司 Compositions and methods for the diagnosis and treatment of tumor
JP5988436B2 (en) 2010-02-23 2016-09-07 ジェネンテック， インコーポレイテッド Compositions and methods for tumor diagnosis and treatment
KR20130079384A (en) 2010-05-03 2013-07-10 제넨테크, 인크. Compositions and methods for the diagnosis and treatment of tumor
AU2012230899A1 (en) 2011-03-21 2013-10-10 Biodesy, Llc Classification of kinase inhibitors using nonlinear optical techniques
KR20140068062A (en) 2011-09-15 2014-06-05 제넨테크, 인크. Methods of promoting differentiation
MX2014004426A (en) 2011-10-15 2014-07-09 Genentech Inc Scd1 antagonists for treating cancer.
RU2014133547A (en) 2012-01-18 2016-03-10 Дженентек, Инк. WAYS OF APPLICATION OF FGF19 MODULATORS
CN104718220A (en) 2012-02-11 2015-06-17 霍夫曼-拉罗奇有限公司 R-spondin translocations and methods using the same
KR20140142293A (en) 2012-03-16 2014-12-11 제넨테크, 인크. Engineered conformationally-stabilized proteins
RU2014141018A (en) 2012-03-16 2016-05-10 Ф. Хоффманн-Ля Рош Аг METHODS OF TREATING MELANOMA WITH CANCER INHIBITORS
US9139863B2 (en) 2012-03-16 2015-09-22 Genentech, Inc. Engineered conformationally-stabilized proteins
CN104583776B (en) 2012-04-25 2016-09-07 比奥德赛公司 For the method detecting the allosteric modulators of protein
WO2013170191A1 (en) 2012-05-11 2013-11-14 Genentech, Inc. Methods of using antagonists of nad biosynthesis from nicotinamide
RU2701378C2 (en) 2013-03-15 2019-09-26 Дженентек, Инк. Biomarkers and methods of treating associated with pd-1 and pd-l1 conditions
WO2015116902A1 (en) 2014-01-31 2015-08-06 Genentech, Inc. G-protein coupled receptors in hedgehog signaling
JP2017524371A (en) 2014-05-23 2017-08-31 ジェネンテック， インコーポレイテッド MIT biomarkers and methods of use
US10562946B2 (en) 2014-06-20 2020-02-18 Genentech, Inc. Chagasin-based scaffold compositions, methods, and uses
EP3237906B8 (en) 2014-12-23 2020-10-28 Bluelight Therapeutics, Inc. Attachment of proteins to interfaces for use in nonlinear optical detection
JP6952605B2 (en) 2015-04-24 2021-10-20 ジェネンテック， インコーポレイテッド Multispecific antigen binding protein
WO2018049275A1 (en) 2016-09-09 2018-03-15 Genentech, Inc. Selective peptide inhibitors of frizzled
WO2018152496A1 (en) 2017-02-17 2018-08-23 The Usa, As Represented By The Secretary, Dept. Of Health And Human Services Compositions and methods for the diagnosis and treatment of zika virus infection
US11236151B2 (en) 2017-04-25 2022-02-01 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Antibodies and methods for the diagnosis and treatment of Epstein Barr virus infection
US11827669B2 (en) 2017-07-19 2023-11-28 The Usa, As Represented By The Secretary, Dept. Of Health And Human Services Antibodies and methods for the diagnosis and treatment of hepatitis b virus infection
JP7397884B2 (en) 2019-05-09 2023-12-13 ジェネンテック， インコーポレイテッド How to make antibodies

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3717705A (en) * 1969-01-16 1973-02-20 M Sela Protein-bacteriophage conjugates
WO1988006630A1 (en) * 1987-03-02 1988-09-07 Genex Corporation Method for the preparation of binding molecules

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3717705A (en) * 1969-01-16 1973-02-20 M Sela Protein-bacteriophage conjugates
WO1988006630A1 (en) * 1987-03-02 1988-09-07 Genex Corporation Method for the preparation of binding molecules

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
I. KATSURA.: "Mechanism of length determination in Bacteriophage Lambda tails.", ADV. BIOPHYS., vol. 26, 1990, pages 1 - 18, XP000646027 *
I.N. MARUYAMA ET AL.: "Lambda foo: a lambda phage vector for the expression of foreign proteins.", PROC. NATL. ACAD. SCI. USA, vol. 91, no. 17, August 1994 (1994-08-01), pages 8273 - 8277, XP000647491 *
N.K. ABULADZE ET AL.: "Tail length determination in bacteriophage T4", VIROLOGY, vol. 199, March 1994 (1994-03-01), pages 301 - 310, XP000647480 *
S.F. PARMLEY ET AL.: "Antibody-selectable filamentous fd phage vectors: affinity purification of target genes.", GENE, vol. 73, 1988, pages 305 - 318, XP002029963 *
See also references of WO9534683A1 *

Also Published As

Publication number Publication date
WO1995034683A1 (en) 1995-12-21
EP0760012A1 (en) 1997-03-05
AU7104294A (en) 1996-01-05

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