EP0431045A4 - Retroviral vectors expressing soluble cd4; a gene therapy for aids - Google Patents

Retroviral vectors expressing soluble cd4; a gene therapy for aids

Info

Publication number
EP0431045A4
EP0431045A4 EP19890909945 EP89909945A EP0431045A4 EP 0431045 A4 EP0431045 A4 EP 0431045A4 EP 19890909945 EP19890909945 EP 19890909945 EP 89909945 A EP89909945 A EP 89909945A EP 0431045 A4 EP0431045 A4 EP 0431045A4
Authority
EP
European Patent Office
Prior art keywords
aids
gene therapy
retroviral vectors
vectors expressing
expressing soluble
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP19890909945
Other versions
EP0431045A1 (en
Inventor
W. French Anderson
Robert C. Gallo
Flossie Wong-Staal
Richard A. Morgan
Daryl Muenchau
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
THE UNITED STATES OF AMERICA REPRESENTED BY THE SE
Original Assignee
US Department of Commerce
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by US Department of Commerce filed Critical US Department of Commerce
Publication of EP0431045A1 publication Critical patent/EP0431045A1/en
Publication of EP0431045A4 publication Critical patent/EP0431045A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70514—CD4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
EP19890909945 1988-08-22 1989-08-21 Retroviral vectors expressing soluble cd4; a gene therapy for aids Withdrawn EP0431045A4 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US23464688A 1988-08-22 1988-08-22
US234646 1988-08-22
US39545489A 1989-08-18 1989-08-18
US395454 1989-08-18

Publications (2)

Publication Number Publication Date
EP0431045A1 EP0431045A1 (en) 1991-06-12
EP0431045A4 true EP0431045A4 (en) 1991-10-30

Family

ID=26928158

Family Applications (1)

Application Number Title Priority Date Filing Date
EP19890909945 Withdrawn EP0431045A4 (en) 1988-08-22 1989-08-21 Retroviral vectors expressing soluble cd4; a gene therapy for aids

Country Status (4)

Country Link
EP (1) EP0431045A4 (en)
JP (1) JPH03505039A (en)
AU (1) AU647013B2 (en)
WO (1) WO1990001870A1 (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1038306A (en) * 1988-03-21 1989-12-27 维吉恩公司 Recombinant retroviruses
US5716826A (en) * 1988-03-21 1998-02-10 Chiron Viagene, Inc. Recombinant retroviruses
ATE174514T1 (en) * 1989-01-23 1999-01-15 Chiron Corp RECOMBINANT CELLS FOR THERAPY OF INFECTIONS AND HYPERPRODELIVERY DISORDERS AND THEIR PRODUCTION
US6251675B1 (en) * 1989-05-25 2001-06-26 Duke University Methods utilizing mutant rev genes encoding transdominant repressors of HIV replication
US5871958A (en) * 1989-05-25 1999-02-16 Duke University Mutant rev genes encoding transdominant repressors of HIV replication
WO1995004824A1 (en) * 1993-08-05 1995-02-16 Medvet Science Pty. Ltd. Generation of dna libraries and retroviral vectors for same
US5498537A (en) * 1994-03-09 1996-03-12 Cellco, Inc. Serum-free production of packaged viral vector
EP0893507A1 (en) * 1997-07-25 1999-01-27 Institut Gustave Roussy Use of MHC class II ligands (CD4 and LAG-3) as adjuvant for vaccination and of LAG-3 in cancer treatment
EP1088892A1 (en) * 1999-09-24 2001-04-04 Vlaams Interuniversitair Instituut voor Biotechnologie vzw. Recombinant phages capable of entering host cells via specific interaction with an artificial receptor
US6479280B1 (en) 1999-09-24 2002-11-12 Vlaams Interuniversitair Institutuut Voor Biotechnologie Vzw Recombinant phages capable of entering host cells via specific interaction with an artificial receptor
DE10063111A1 (en) * 2000-12-18 2002-06-20 Bayer Ag Replication assay for the detection of antiviral substances

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2559159A1 (en) * 1984-02-02 1985-08-09 Inst Nat Sante Rech Med VIRAL CLONING AND PROTEIN EXPRESSION VECTORS IN EUKARYOTIC CELL COMPRISING AT LEAST ONE PART OF THE GENOME OF A RETRO-VIRUS; TRANSFECTED EUCARYOTIC CELLS; PROCESS USING SUCH CELLS AND PROTEINS OBTAINED

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4686098A (en) * 1984-05-14 1987-08-11 Merck & Co., Inc. Encapsulated mouse cells transformed with avian retrovirus-bovine growth hormone DNA, and a method of administering BGH in vivo
JP3134874B2 (en) * 1986-08-21 2001-02-13 ザ・トラステイーズ・オブ・コロンビア・ユニヴアーシテイ・イン・ザ・シテイ・オブ・ニユー・ヨーク Use of DNA encoding T cell surface protein T4 and T4 fragment for AIDS treatment

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2559159A1 (en) * 1984-02-02 1985-08-09 Inst Nat Sante Rech Med VIRAL CLONING AND PROTEIN EXPRESSION VECTORS IN EUKARYOTIC CELL COMPRISING AT LEAST ONE PART OF THE GENOME OF A RETRO-VIRUS; TRANSFECTED EUCARYOTIC CELLS; PROCESS USING SUCH CELLS AND PROTEINS OBTAINED

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
NATURE, vol. 328, 23rd July 1987, pages 351-353; B.P. SLECKMAN et al.: "Expression and function of CD4 in a murine T-cell hybridoma" *
NATURE, vol. 334, 14th July 1988, pages 162-165; P. BEDINGER et al.: "Internalization of the human immuno-deficiency virus does not require the cytoplasmic domain of CD4" *
See also references of WO9001870A1 *

Also Published As

Publication number Publication date
JPH03505039A (en) 1991-11-07
AU4193289A (en) 1990-03-23
EP0431045A1 (en) 1991-06-12
AU647013B2 (en) 1994-03-17
WO1990001870A1 (en) 1990-03-08

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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17P Request for examination filed

Effective date: 19910222

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Effective date: 19910921

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18D Application deemed to be withdrawn

Effective date: 19960622