DE10351109A1 - Cleansing preparations, e.g. shampoos, containing ubiquinone as antioxidant and combination of surfactants, cationic polymers and polyethylene glycol-3 stearate providing improved substantivity - Google Patents

Abstract

New cosmetic and/or dermatological cleansing preparations contain: (a) a surfactant combination of alkyl ether sulfate, cocamidopropyl betaine and optionally citric acid alkyl polyglycol ester sulfosuccinate disodium salt; (b) a cationic polymer combination of polyquaternium-10 and quaternized guar; (c) at least one ubiquinone; and (d) polyethylene glycol-3 distearate.

Description

The The present invention relates to a cleansing preparation with ubiquinones and their use.

at the body care the human plays the hair wash a central role. The cleaning of the hair and scalp of autologous Fat, Hautabschilferungen, dirt and odors corresponds to a basic need of People.

to Satisfaction of this need Until the twentieth century, soap was the only food available to man available which was poorly tolerated by the scalp and ocular mucosa due to its alkaline pH and often Deposits of lime soap left in the hair. In the thirties of the 20th century saw the first alkyl sulfate-containing shampoo The Light of the World. Since the mid-sixties alkyl ether sulfates conquer and other surfactants on the shampoo market. With them, the disadvantages of soap-containing Preparations are avoided. Nowadays, modern shampoos need hair not only clean and well tolerated be. Rather, they should also care for the hair and its manageability and visual appeal increase.

Hair shampoos contain a variety of different components to meet the individual requirements of the product:
The cleaning power of the shampoos is brought about by the presence of anionic, amphoteric and nonionic surfactants as surface-active compounds in the preparations. Surfactants also ensure the foaming power of the hair cleanser. In addition, their insensitivity to water hardness, their biodegradability, their compatibility with other components of the preparation and their price are important in the selection of surfactants. A much-used shampoo surfactant is, for example, alkyl ether sulfate.

Furthermore Shampoos contain a number of consistency regulators that the Prepare the desired viscosity to lend. These thickeners cause an enlargement of the surfactant micelles or a swelling of the water phase of the preparation. Thickeners may be out be selected chemically very different classes. So u.a. Electrolytes (e.g., sodium chloride), alkanolamides (e.g., fatty acid monoethanolamides), low ethoxylated fatty alcohols (e.g., diethylene glycol monolauryl ether), highly ethoxylated ethers, esters and diesters as well as polymeric thickeners used. The polymeric thickeners include, for example, cellulose ethers. About that In addition, find polyacrylates and hydrocolloids as thickeners Use. Polymer thickeners have the great advantage of being through she produced viscosity largely independent of temperature is.

Next Perfume- and dyes, as well as a range of compounds that improve durability increase the preparations, become younger Time added to the hair shampoos different types of active ingredients. For this counting including UV absorbers, vitamins, plant extracts, anti-dandruff, hair conditioner (Conditioner) and antioxidants, such as ubiquinones.

ubiquinones are a group of substances that are n isoprene units on their quinone ring chain-like have tied. Ubiquinones act at the biological, mitochondal Oxidation as an electron transfer agent and play an important role in the energy metabolism of the cells.

The Ubiquinones are known from the literature (e.g., Beyer, Walter, Lehrbuch of Organic Chemistry, S. Hirzel Verlag, Stuttgart, 22nd Edition). They are also referred to as mitochinones or coenzymes Q. The number the isoprene units in the side chain is denoted by n in the name Coenzyme Q-n, where n is an integer. There are Coenzymes of n = 0 to n = 12 known. Most common, however, are n = 6-10.

In Ubiquinones have long been used in cosmetic preparations as antioxidants for the protection of oxidation-sensitive substances.

Also in hair cosmetic preparations is the use of ubiquinones have been described repeatedly as antioxidants. They will in particular to protect against the negative effects of sunlight on the Hair, the protection against mechanical stress (such as combing or To brush) and for the protection and / or treatment of the consequences of dyeing and Bleaching the hair used.

This is what the DE 199 26 167 and the DE 199 26 168 Styling agent with ubiquinones. In the DE 199 26 177 hair care products (especially hair treatments) are described which contain ubiquinones. The state of the art disclosed in these documents has in common that they are surfactant-free preparations remaining on the hair (so-called leaveon products).

The DE 44 343 12 and especially the DE 199 26 170 describe shampoo preparations containing ubiquinones.

adversely However, the state of the art is the fact that the ubiquinones and in particular ubiquinone Q-10 especially in cleaning preparations (Shampoos) after use at best in traces on the hair stick and the desired To be effective. The expert speaks here of a low substantivity of the active ingredient on the hair. This is, of course, because a large part of the Active ingredients after application of the preparation by the water rinse again be washed out. This effect is due to the in the cleaning preparation containing surfactants still reinforced. On the other hand, it is due to the relatively low concentration, with the ubiquinone can be used in the preparations. Of the nearest Solution - an increase in the Ubiquinone concentration in the preparations - has been in the past as impractical, since Ubichinone are very expensive and the Total price of the shampoo in an unreasonable way to boost would. On the other hand can be higher Do not incorporate concentrations of ubiquinone in the preparations in a stable manner.

It It was therefore the object of the present invention to contain ubiquinone to develop cosmetic cleansing preparations in which the substantivity of ubiquinone during and after the application compared to the prior art clearly elevated is. The term "increased substantivity" is understood according to the invention, that a larger amount of ubiquinone per area or volume unit after application of the preparation on the hair (or other body surface e.g. the skin, the scalp, the nails) remains as with comparable preparations of the state the technique is the case. Furthermore, it was the task of the present Invention cosmetic cleaning preparations and in particular shampoos to develop, which increased one Protection of the hair, as well as the skin (especially the scalp) and the nails from the negative effects of sunlight (in particular the UV light), an elevated Protection against mechanical stress (such as combing or brushing) and increased protection from other oxidative attacks and / or stresses. Further A preparation should be developed to help protect the hair before the effects of dyeing and bleaching the hair and treating the effects of dyeing and Bleaching a higher Efficiency than the products of the prior art.

• a) eine Tensidkombination aus – Alkylethersulfat, – Cocamidopropylbetain,
• b) eine Kombination kationischer Polymerer aus – Polyquaternium-10 und – quaternisiertem Guar
• c) ein oder mehrere Ubichinone,
• d) Polyethylenglykol-3-distearat.

The objects are surprisingly achieved by containing a cosmetic and / or dermatological cleansing preparation

• a) a surfactant combination of alkyl ether sulfate, - cocamidopropyl betaine,
• b) a combination of cationic polymers of polyquaternium-10 and quaternized guar
• c) one or more ubiquinones,
• d) Polyethylene glycol 3-distearate.

• a) eine Tensidkombination aus – Alkylethersulfat, – Cocamidopropylbetain, – Dinatriumsalz des Citronensäurealkylpolyglykolester-sulfosuccinats,
• b) eine Kombination kationischer Polymerer aus – Polyquaternium-10 und – quaternisiertem Guar
• c) ein oder mehrere Ubichinone,
• d) Polyethylenglykol-3-distearat.

In particular, the objects of the invention are achieved particularly well by containing a cosmetic and / or dermatological cleansing preparation

• a) a surfactant combination of alkyl ether sulfate, cocamidopropyl betaine, disodium salt of citric acid alkylpolyglycol ester sulfosuccinate,
• b) a combination of cationic polymers of polyquaternium-10 and quaternized guar
• c) one or more ubiquinones,
• d) Polyethylene glycol 3-distearate.

The preparations of the invention differ from those in the DE 199 26 170 disclosed preparations by the content of three additional ingredients (disodium salt of Citronensäurealkylpolyglykolester sulfosuccinate, quaternized guar and polyethylene glycol-3-distearate), in the inventive combination with alkyl ether sulfate, Cocamidopropylbetain and Polyquaternium-10 to a surprising surprising for the skilled person increasing the substantivity of the ubiquinone hair (skin, scalp, nails).

It is advantageous according to the invention when the preparation of the invention Alkyl ether sulfates in a total concentration of 5 to 25% by weight and preferably in a total concentration of 6 to 20% by weight and more preferably in a total concentration of 7 to 18 % By weight, in each case based on the total weight of the preparation, contains.

Advantageous For the purposes of the present invention, one or more alkyl ether sulfates selected from the list of the following compounds: sodium lauryl ether sulfate, Sodium myristyl ether sulfate, ammonium lauryl ether sulfate, ammonium myristyl ether sulfate, Potassium lauryl ether sulfate, potassium myristyl ether sulfate, magnesium lauryl ether sulfate, Magnesiummyristylethersulfat.

According to the invention preferred is the use of the Alkylethersulfates the type of sodium lauryl ether.

Advantageous For the purposes of the present invention, cocamidopropyl betaine in a concentration of 1 to 10% by weight, preferably in one Concentration of 1.5 to 9% by weight and more preferably in a concentration of 2 to 8% by weight, based in each case on the total weight of the preparation.

Advantageous For the purposes of the present invention is disodium salt of Citronensäurealkylpolyglykolester sulfosuccinate in a concentration of 1 to 10% by weight, preferably in one Concentration of 1.5 to 8% by weight and more preferably in a concentration of 2 to 6% by weight, based in each case on the total weight of the preparation.

According to the invention preferred Disodium salts of Citronensäurealkylpolyglykolestersulfosuccinate are the disodium PEG-5 lauryl citrate sulfosuccinate.

Especially the Rewopol SB CS 50 K from Degussa is preferred.

Advantageous For the purposes of the present invention, it is Polyquaternium-10 in a concentration of 0.01 to 2% by weight, preferably in one Concentration of 0.05 to 1.5% by weight and more preferred from 0.1 to 1.0% by weight, based in each case on the total weight the preparation to use.

Polyquaternium-10 according to the invention means polymers which are formed from quaternized ammonium salt of hydroxypropyl cellulose substituted with a trimethylammonium ized epoxy is modified. It is advantageous according to the invention if polyquaternium-10 has an average molecular weight of from 200,000 to 1,000,000 and a charge density of from 0.8 to 1.8 meq / g. Polyquaternium-10 which is particularly preferred according to the invention is Ucare Polymer JR 400 from Amerchol.

Advantageous For the purposes of the present invention, it is quaternized guar in a concentration of 0.01 to 3% by weight, preferably in one Concentration of 0.05 to 2% by weight and more preferably in a concentration of 0.01 to 1% by weight, based in each case the total weight of the preparation.

According to the invention advantageous is selected as quaternized guar one or more compounds from the group of guar hydroxypropyltrimethylammonium chlorides, which belongs to the class of galactomannan 2-hydroxypropyltrimethylammonium chloride ethers belong, have an average molecular weight of 600,000 to 2,000,000 and have a charge density of 0.4 to 1.0 meq / g. According to the invention are preferred Guar Hydroxypropyltrimethylammoniumchloride chosen from the Jaguar series, Jaguar Excel the company Rhodia according to the invention very particularly is preferred.

Advantageous For the purposes of the present invention, it is ubiquinone in one Concentration of 0.00001 to 1% by weight, preferably in one concentration from 0.0001 to 0.75% by weight and more preferably in one Concentration of 0.001 to 0.5% by weight, based in each case the total weight of the preparation.

Particularly according to the invention the use of the ubiquinone Q-10 is preferred.

Advantageous For the purposes of the present invention, it is polyethylene glycol-3-distearate (PEG-3 distearate (e.g., CUTINA TS from Cognis)) at one concentration from 0.5 to 3% by weight, preferably in a concentration of 1 to 2.5% by weight and especially preferably in a concentration of 1.5 to 2% by weight, respectively based on the total weight of the preparation to use.

According to the invention advantageous can the preparation of the invention one or more other washing-active substances (surfactants, polysorbates) contain.

According to the invention, the preparation according to the invention advantageously contains one or more further active ingredients. This can be according to the invention preferably chosen from the group of anti-dandruff agents such as climbazole, octopirox ^®, vitamins and provitamins such as panthenol (provitamin B5), niacinamide (vitamin B3), Biotin (Vitamin H), Vitamin E and Vitamin E acetate, plant extracts, such as bamboo extract, water-lily extract, the alpha-hydroxy acids, such as citric acid, tartaric acid, malic acid, salts, such as calcium salts or marine minerals, the antioxidants, such as gamma-oryzanol, BHT, propyl gallate, UV filters, such as benzophenone. 4

each These compounds can be in a concentration of 0.001 to 3 % By weight, based on the total weight of the preparation, in this be included.

Further it is advantageous according to the invention when in the preparations according to the invention Salts are used. These lead to a thickening of the preparation, so that preparations with viscosities of 2000 mPas to 6000 mPas can be produced. Salts include or polyvalent alkali metal compounds or alkaline earth metal compounds to understand with halogen anions. Particularly preferred is sodium chloride used.

of course is the expert a variety of ways known, stable surfactant-containing preparations for cosmetic or dermatological use, for example in form of highly viscous gels ranging from room to skin temperature are little or not flowable, or in the form of low-viscosity gels, in this temperature range are more fluid.

Under The term "viscosity" is understood to mean the Property of a liquid, the mutual laminar displacement of two adjacent layers a resistance (toughness, internal friction). One defines today these so-called dynamic viscosity after η = τ / D as the relationship the shear stress to the velocity gradient perpendicular to the flow direction. For Newtonian liquids is η in given temperature a substance constant with the SI unit Pascal seconds (Pas).

The quotient v = η / ρ from the dynamic viscosity η and the density ρ of the liquid is called kine matic viscosity ν and indicated in the SI unit m ² / s.

When fluidity (φ) the reciprocal of the viscosity (φ = 1 / η). For ointments and the like, the use value is determined among others from the so-called speed. Under the speed an ointment or ointment base or the like is meant by them Property of pulling threads of different lengths when cutting off; accordingly a distinction is made between short and long-lasting substances.

While the graphical representation of the flow behavior Newtonian fluids at a given temperature results in a straight line, show in the so-called non-Newtonian fluids dependent on from the respective velocity gradient D (shear rate γ.) or the shear stress τ often significant deviations. In these cases, the so-called apparent viscosity which does not obey Newton's equation However, by graphic methods, the true viscosity values can be determined.

bestimmbar ist, wobei
r = Radius der Kugel, v = Fallgeschwindigkeit, ρ_K = Dichte der Kugel, ρ_FI = Dichte der Flüssigkeit und g = Fallbeschleunigung.Falling body viscometry is only suitable for studying Newtonian fluids and gases. It is based on the Stokes law, according to which for the falling of a ball by a liquid flowing around it, the dynamic viscosity η from

is determinable, where
r = radius of the sphere, v = velocity of the fall, ρ _K = density of the sphere, ρ _FI = density of the liquid and g = acceleration of gravity.

The in the context of the present specification listed viscosity values The preparations and individual substances were determined using a viscometer Viscotester VT 02 from Haake (measured at 25 ° C, one Shear rate of 10 Pa / s).

It is according to the invention of advantage one or more alkali metal salts or alkaline earth metal salts in one concentration from 0.01 to 3% by weight, based on the total weight of the preparation use.

at With salts difficult to thicken compositions, it is advantageous according to the invention, when in the preparations according to the invention Thickener can be used. These can be advantageous, for example be selected from further compounds of the group of gums.

To counting the gums you plant or tree juices, which harden in the air and resins or extracts from aquatic plants. From this group can be selected advantageously in the context of the present invention for example gum arabic, locust bean gum, tragacanth, karaya, Guar gum, pectin, gellan gum, carrageenan, agar, algine, chondrus, Xanthan gum.

Also advantageous is the use of derivatized gums such as hydroxypropyl guar ( ^Jaguar® HP 8).

Under the polysaccharides and derivatives are e.g. Hyaluronic acid, chitin and chitosan, chondroitin sulfates, starch and starch derivatives as being advantageous according to the invention Thickener.

Under the cellulose derivatives are e.g. Methylcellulose, carboxymethylcellulose, Hydroxyethylcellulose, hydroxypropylmethylcellulose as advantageous according to the invention Thickener.

The phyllosilicates include naturally occurring and synthetic clays such as montmorillonite, bentonite, hectorite, laponite, magnesium aluminum silicates such as Veegum ^®. These can be used as such or in modified form as thickeners such as stearylalkonium hectorites.

Farther can also advantageous silica gel be used.

Under the polyacrylates are e.g. Carbopol types from Noveon (Carbopol 980, 981, 1382, 5984, 2984, ETD 2001, ETD 2020, ETD 2050 or Pemulen TR1 & TR2).

Under the polymers are e.g. Polyacrylamide (Seppigel 305), Polyvinyl alcohols, PVP, PVP / VA copolymers, polyglycols.

It is according to the invention of advantage one or more thickeners in a concentration of 0.1 to 5% by weight, based on the total weight of the preparation use.

It is also advantageous, the preparations according to the invention complexing agents add. Advantageously, the complexing agents are selected from the group consisting of ethylenediaminetetraacetic acid (EDTA) and their anions, nitrilotriacetic acid (NTA) and their anions, hydroxyethylenediaminotriacetic acid (HOEDTA) and their anions, diethyleneaminopentaacetic acid (DPTA) and their anions, trans-1,2-diaminocyclohexanetetraacetic acid (CDTA) and its anions, Tetrasodium Iminodisuccinate, Trisodium Etylenediamine Disuccinate.

Advantageous, though not mandatory, can the preparations according to the invention Preservative included.

Advantageous preservatives for the purposes of the present invention are, for example, formaldehyde releasers (such as DMDM hydantoin, which is available, for example, under the trade name Glydant ^™ from Lonza), iodopropyl butylcarbamates (for example those sold under the trade names Glycacil-L, Glycacil -S. From the company. Lonza available and / or Dekaben LMB from Jan Dekker), parabens (ie p-Hydroxybenzoesäurealkylester, such as methyl, ethyl, propyl and / or Butylparaben), phenoxyethanol, ethanol, benzoic acid and the like. Usually, the preservation system according to the invention also advantageously also preserving aids, such as octoxyglycerol, glycine soy, etc. This list of advantageous preservatives should be by no means limiting. Rather, all approved for cosmetics or food preservatives are advantageous in the context of the present invention.

The aqueous Phase of the preparations according to the invention can be beneficial usual contain cosmetic excipients, such as alcohols, especially such low C number, preferably ethanol and / or isopropanol, diols or polyols lower C number and their ethers, preferably propylene glycol, glycerol, Butylene glycol, ethylene glycol, ethylene glycol monoethyl or monobutyl ether, Propylene glycol monomethyl, monoethyl or monobutyl ether, diethylene glycol monomethyl or monoethyl ethers and analogues, polymers, foam stabilizers, Electrolytes, and in particular one or more thickeners, which or which can be chosen advantageously from the group silicon dioxide, aluminum silicates, polysaccharides or their derivatives, eg. Hyaluronic acid, Xanthan gum, hydroxypropyl methylcellulose, particularly advantageous from the group of polyacrylates, preferably a polyacrylate from the Group of so-called Carbopols [from the company Noveon], for example Carbopols Types 980, 981, 1382, 2984, 5984, ETD 2020, ETD 2050, Ultrez 10, either individually or in combination.

The cosmetic preparations according to the invention can contain cosmetic excipients, such as those commonly used in such preparations be used, for. B. preservatives, complexing agents, antioxidants, Buffers, solubilizers, Dispersants, bactericides, perfumes, substances for preventing or Increasing the foaming, Dyes, pigments that are a coloring Have thickening agents, pearlescent pigments, softening, moisturizing and / or moisturizing substances, fats, oils, waxes or other usual Components of a cosmetic or dermatological formulation such as emulsifiers, alcohols, polyols, polymers, foam stabilizers, Electrolytes, organic solvents or silicone derivatives.

The Compositions according to the invention except the above-mentioned substances optionally the usual in cosmetics Additives, for example perfume, dyes, antimicrobial Substances, moisturizing Agents, complexing and sequestering agents, pearlescent agents, Antidandruff active ingredients, plant extracts, vitamins, active ingredients.

Further it is within the meaning of the present invention, the preparation of the invention Pearlescent pigments, mica and / or effect pigments to add make the preparation visually attractive.

It is advantageous according to the invention if the cosmetic according to the invention Preparation in a bottle, squeeze bottle, pump spray or aerosol can stored and used out of this. Corresponding are also bottles, squeeze bottles, double-chamber packaging, pump spray, or aerosol cans containing a preparation according to the invention, according to the invention.

According to the invention Use of the preparation according to the invention as a hair shampoo. But also the use of the preparation according to the invention as a shower preparation or bath is according to the invention.

Also according to the invention the use of the preparation according to the invention to increase the substantivity of ubiquinones in cosmetic cleansing preparations.

According to the invention Use of a combination of quaternized guar and polyethylene glycol-3-distearate to increase the substantivity of ubiquinones in cosmetic cleansing preparations.

According to the invention Use of a combination of disodium salt of citric acid alkylpolyglycol ester sulfosuccinate, quaternized guar and polyethylene glycol 3-distearate for increasing the substantivity of ubiquinones in cosmetic cleansing preparations.

The The following examples are intended to illustrate the compositions according to the invention without but it is intended that the invention be accorded these examples restrict. The numerical values in the examples mean percentages by weight on the total weight of the respective preparations.

Examples

Claims (10)

Cosmetic and / or dermatological cleaning preparation comprising a) a surfactant combination of - alkyl ether sulfate, - Cocamidopropylbetain, b) a combination of cationic polymers Polyquaternium-10 and quaternized guar c) one or more ubiquinones, d) polyethylene glycol-3-distearate. Cosmetic and / or dermatological cleansing preparation containing a) a surfactant combination of. Alkyl ether sulfate, - cocamidopropyl betaine, - disodium salt citric acid alkylpolyglycol ester sulfosuccinate, b) a combination of cationic polymers - Polyquaternium-10 and - quaternised guar c) one or more ubiquinones, d) Polyethylene glycol 3-distearate. Preparation according to claim 1 or 2, characterized that it contains: Alkyl ether sulfates in a total concentration of 5 to 25% by weight, Cocamidopropylbetaine in a concentration of 1 to 10% by weight, Disodium salts of citric acid alkylpolyglycol ester sulfosuccinate in a concentration of 1 to 10% by weight, Polyquaternium-10 in a concentration of 0.01 to 2% by weight, quaternized guar in a total concentration of 0.01 to 3% by weight, ubiquinones in a total concentration 0.00001 to 1% by weight, polyethylene glycol 3-distearate in a concentration of 0.5 to 3% by weight, in each case on the total weight of the preparation. Preparation according to one of claims 1 to 3, characterized that as ubiquinone the ubiquinone Q-10 is used. Preparation according to one of claims 1 to 4, characterized that is used as alkyl ether sulfate sodium lauryl ether sulfate. Preparation according to one of claims 1 to 5, characterized as quaternized guar guar hydroxypropyl trimethyl ammonium chloride contains. Preparation according to one of claims 1 to 6, characterized in that it comprises one or more compounds selected from the group of anti-dandruff agents such as climbazole, octopirox ^®, vitamins and provitamins such as panthenol (provitamin B5), Niacinamide Vitamin B3), Biotin (vitamin H), vitamin E and vitamin E acetate, plant extracts, such as bamboo extract, water-lily extract, the alpha-hydroxy acids, such as citric acid, tartaric acid, malic acid, salts, such as calcium salts or marine minerals, the antioxidants, such as gamma- Oryzanol, BHT, propyl gallate, UV filters such as benzophenone-4. Use of a preparation according to one of the preceding claims as a hair shampoo. Use of a preparation according to one of the preceding claims as a shower preparation or bath. Use of a preparation according to one of the preceding claims to increase the substantivity of ubiquinones in cosmetic cleansing preparations.