CN214408662U - Volume optical coherence tomography vibration measurement system - Google Patents
Volume optical coherence tomography vibration measurement system Download PDFInfo
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- CN214408662U CN214408662U CN202120098686.8U CN202120098686U CN214408662U CN 214408662 U CN214408662 U CN 214408662U CN 202120098686 U CN202120098686 U CN 202120098686U CN 214408662 U CN214408662 U CN 214408662U
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Abstract
The utility model discloses a volume optical coherence tomography vibration measurement system, include: the light source module is connected with the acquisition and control module, the main Mach-Zehnder interferometer module, the calibration Mach-Zehnder interferometer module and the scanning module, the calibration Mach-Zehnder interferometer module is also connected with the acquisition control module, the main Mach-Zehnder interferometer module is connected with the acquisition control module and the scanning module, and the scanning module is also connected with the acquisition control module. The method has the advantages that the interference signals of the sample light and the reference light are completely and efficiently detected by the detector through the main Mach-Zehnder interferometer module, the Mach-Zehnder interferometer module is calibrated, the interference spectrum signals are calibrated in real time by using the Mach-Zehnder interferometer, the axial resolution can be obviously improved, the sweep frequency OCT system can display the image of one cross section in the sample in real time, and the acquisition and control module realizes hardware synchronization and data acquisition through a multifunctional data acquisition card, a function generator and the like which are integrated in a computer.
Description
Technical Field
The utility model relates to an optics technical field, more specifically the utility model relates to a volume optical coherence tomography vibration measurement system that says so.
Background
Currently, Optical Coherence Tomography (OCT) is a biomedical optical imaging method that can perform in-vivo non-destructive imaging on a sample to be measured. Has the advantages of high resolution, non-invasion, no radiation, etc.
However, although the LDV has the characteristics of non-contact, high precision, high resolution, etc., it cannot be imaged; the LDV needs to adopt a cochlear windowing method to enable the laser beam to reach the basement membrane, there is a limit to the measurement location, and the vibration mode can be changed by the pressure change, temperature change or mechanical trauma caused by windowing; success rates for experimental results of LDV are generally accepted to be 5% to 50%.
Therefore, providing a swept-source and single-point detector to detect time-coded spectral information has the same fast imaging capability as spectral-domain OCT, and meanwhile, having point detection of time-domain OCT is a problem that needs to be solved by those skilled in the art.
SUMMERY OF THE UTILITY MODEL
In view of this, the utility model provides a volume optical coherence tomography vibration measurement system, through main mach DE interferometer module, guarantee that the interference signal of sample light sum reference light is surveyed by the detector is efficient completely, mark mach DE interferometer module, use mach-Zehnder interferometer to mark interference spectral signal in real time, can show improvement axial resolution, frequency-sweeping OCT system can show the image of the inside cross section of sample in real time, gather and realize hardware synchronization and data acquisition such as control module through multi-functional data collection card and function generator of integration in the computer.
In order to achieve the above purpose, the utility model adopts the following technical scheme:
a volumetric optical coherence tomography vibrometry system comprising: the device comprises a light source module, a main Mach-Zehnder interferometer module, a calibration Mach-Zehnder interferometer module, a scanning module and an acquisition and control module; the light source module is connected with the acquisition and control module, the main Mach-Zehnder interferometer module, the calibration Mach-Zehnder interferometer module and the scanning module, the calibration Mach-Zehnder interferometer module is also connected with the acquisition control module, the main Mach-Zehnder interferometer module is connected with the acquisition control module and the scanning module, and the scanning module is also connected with the acquisition control module.
Preferably, the light source module includes a positioning laser, an optical frequency comb-swept laser light source, a first broadband fiber coupler, a conventional swept laser light source, and an optical switch, the positioning laser is connected to the main mach-zehnder interferometer module, the optical frequency comb-swept laser light source is connected to the optical switch, the conventional swept laser light source is connected to the first broadband fiber coupler, and the first broadband fiber coupler is further connected to the optical switch and the calibration mach-zehnder interferometer module.
Preferably, the calibration mach-zehnder interferometer module includes a second broadband fiber coupler, a first polarization controller, a second polarization controller, a first variable attenuator, a second variable attenuator, a first variable retarder, a second variable retarder, a third broadband fiber coupler, and a first balanced detector, one end of the second broadband optical fiber coupler is connected with the light source module, the other end of the second broadband optical fiber coupler is connected with the first balance detector through the first polarization controller, the first variable attenuator, the first variable retarder and the third broadband optical fiber coupler in sequence, the other end of the second broadband fiber coupler is further connected with the first balanced detector sequentially through the second polarization controller, the second variable attenuator, the second variable retarder and the third broadband fiber coupler, and the first balanced detector is connected with the acquisition control module.
Preferably, the main mach-zehnder interferometer module includes a fourth broadband optical fiber coupler, an optical fiber circulator, a fifth broadband optical fiber coupler, a third polarization controller, a fourth polarization controller, a third variable attenuator, a third variable retarder, a sixth broadband optical fiber coupler, and a second balanced detector, one end of the fourth broadband optical fiber coupler is connected to the light source module, the other end of the fourth broadband optical fiber coupler is connected to the fifth broadband optical fiber coupler through the optical fiber circulator, the fifth broadband optical fiber coupler is connected to the scanning module, the other end of the fourth optical fiber coupler is further connected to the second balanced detector through the third polarization controller, the third variable attenuator, the third variable retarder, and the sixth broadband optical fiber coupler in sequence, and the optical fiber circulator is further connected to the second balanced detector through the fourth polarization controller and the sixth broadband optical fiber coupler in sequence The second balance detector is connected with the acquisition control module.
Preferably, the scanning module includes an optical fiber collimating mirror, a two-dimensional scanning vibration mirror and a dichroic mirror, the optical fiber collimating mirror is connected to the main mach-zehnder interferometer module, the two-dimensional scanning vibration mirror is connected to the acquisition control module, the optical fiber collimating mirror is optically connected to the two-dimensional scanning vibration mirror, and the two-dimensional scanning vibration mirror is optically connected to the dichroic mirror.
Preferably, the acquisition control module comprises a computer, an acquisition card and a function generator, the computer is connected with the acquisition card and the function generator, the acquisition card is connected with the light source module, the main mach-zehnder interferometer module and the calibrated mach-zehnder interferometer module, and the function generator is connected with the scanning module.
Can know via foretell technical scheme, compared with the prior art, the utility model discloses a volume optical coherence tomography vibration measurement system, through main mach-zeng DE interferometer module, guarantee that the interference signal of sample light sum reference light is totally by the efficient detection of detector, mark mach-zeng DE interferometer module, use mach-zeng interferometer to carry out real-time calibration to interference spectral signal, can show improvement axial resolution, frequency sweep OCT system can show the image of the inside cross section of sample in real time, gather and realize hardware synchronization and data acquisition through integration multifunctional data acquisition card and function generator etc. in the computer with control module.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings required to be used in the description of the embodiments or the prior art will be briefly described below, it is obvious that the drawings in the following description are only embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to the provided drawings without creative efforts.
Fig. 1 is a schematic structural diagram provided by the present invention.
Wherein, 1 is a light source module, 2 is a calibration Mach-Zehnder interferometer module, 3 is a main Mach-Zehnder interferometer module, 4 is a scanning module, 5 is an acquisition control module, 11 is a positioning laser, 12 is an optical frequency comb-swept laser light source, 13 is a conventional swept laser light source, 14 is a first broadband fiber coupler, 15 is an optical switch, 21 is a second broadband fiber coupler, 22 is a first polarization controller, 23 is a second polarization controller, 24 is a first variable attenuator, 25 is a second variable attenuator, 26 is a first variable retarder, 27 is a second variable retarder, 28 is a third broadband fiber coupler, 29 is a first balance detector, 31 is a fourth broadband fiber coupler, 32 is a fiber circulator, 33 is a fifth broadband fiber coupler, 34 is a third polarization controller, 35 is a fourth polarization controller, 36 is a third variable attenuator, 37 is a third variable retarder, 38 is a sixth broadband fiber coupler, 39 is a second balanced detector, 41 is a fiber collimating mirror, 42 is a two-dimensional scanning galvanometer, 43 is a dichroic mirror, 51 is a computer, 52 is an acquisition card, and 53 is a function generator.
Detailed Description
The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention.
The embodiment of the utility model discloses volume optical coherence tomography vibration measurement system, a serial communication port, include: the device comprises a light source module 1, a main Mach-Zehnder interferometer module 3, a calibration Mach-Zehnder interferometer module 1, a scanning module 4 and an acquisition and control module 5; the light source module 1 is connected with the acquisition and control module 5, the main Mach-Zehnder interferometer module 3, the calibration Mach-Zehnder interferometer module 2 and the scanning module 4, the calibration Mach-Zehnder interferometer module 2 is also connected with the acquisition control module 4, the main Mach-Zehnder interferometer module 3 is connected with the acquisition control module 5 and the scanning module 4, and the scanning module 4 is also connected with the acquisition control module 5.
In order to further optimize the technical scheme, the light source module 1 comprises a positioning laser 11, an optical frequency comb frequency sweeping laser light source 12, a first broadband optical fiber coupler 14, a conventional frequency sweeping laser light source 13 and an optical switch 15, the positioning laser 11 is connected with the main Mach-Zehnder interferometer module 3, the optical frequency comb frequency sweeping laser light source 12 is connected with the optical switch 15, the conventional frequency sweeping laser light source 13 is connected with the first broadband optical fiber coupler 14, and the first broadband optical fiber coupler 14 is further connected with the optical switch 15 and the calibrated Mach-Zehnder interferometer module 2.
In order to further optimize the above technical solution, the calibration mach-zehnder interferometer module 2 includes a second broadband fiber coupler 21, a first polarization controller 22, a second polarization controller 23, a first variable attenuator 24, a second variable attenuator 25, a first variable retarder 26, a second variable retarder 27, a third broadband fiber coupler 28, and a first balanced detector 29, one end of the second broadband fiber coupler 21 is connected with the light source module 1, the other end is connected with the first balanced detector 29 through the first polarization controller 22, the first variable attenuator 24, the first variable retarder 26, the third broadband fiber coupler 28 in sequence, the other end of the second broadband fiber coupler 21 is further connected with the first balanced detector 29 through the second polarization controller 23, the second variable attenuator 25, the second variable retarder 27, and the third broadband fiber coupler 28 in sequence, the first balance detector 29 is connected to the acquisition control module 5.
In order to further optimize the technical scheme, the main mach-zehnder interferometer module 3 includes a fourth broadband optical fiber coupler 31, an optical fiber circulator 32, a fifth broadband optical fiber coupler 33, a third polarization controller 34, a fourth polarization controller 35, a third variable attenuator 36, a third variable retarder 37, a sixth broadband optical fiber coupler 38 and a second balance detector 39, one end of the fourth broadband optical fiber coupler 31 is connected with the light source module 1, the other end of the fourth broadband optical fiber coupler 31 is connected with the fifth broadband optical fiber coupler 33 through the optical fiber circulator 32, the fifth broadband optical fiber coupler 33 is connected with the scanning module 4, the other end of the fourth optical fiber coupler 31 is further connected with the second balance detector 39 through the third polarization controller 34, the third variable attenuator 36, the third variable retarder 37 and the sixth broadband optical fiber coupler 38 in sequence, and the optical fiber circulator 32 is further connected with the second balance detector 39 through the fourth polarization controller 35, the sixth broadband optical fiber coupler 38 and the second balance detector 39 in sequence The detector is connected with 39, and the second balance detector 39 is connected with the acquisition control module 5.
In order to further optimize the technical scheme, the scanning module 4 comprises an optical fiber collimating mirror 41, a two-dimensional scanning vibration mirror 42 and a dichroic mirror 43, the optical fiber collimating mirror 41 is connected with the main mach-zehnder interferometer module 3, the two-dimensional scanning vibration mirror 42 is connected with the acquisition control module 5, the optical fiber collimating mirror 41 is optically connected with the two-dimensional scanning vibration mirror 42, and the two-dimensional scanning vibration mirror 42 is connected with the dichroic mirror 43.
In order to further optimize the technical scheme, the acquisition control module 5 comprises a computer 51, an acquisition card 52 and a function generator 53, the computer 51 is connected with the acquisition card 52 and the function generator 53, the acquisition card 52 is connected with the light source module 1, the main mach-zehnder interferometer module 3 and the calibrated mach-zehnder interferometer module 2, and the function generator 53 is connected with the scanning module 4.
The conventional sweep frequency light source in the light source module adopts a sweep frequency laser light source with the center wavelength of 1300nm, the sweep frequency range is 100nm, the sweep frequency rate is 200kHz, and the coherence length is more than 100 nm. The central wavelength of the optical frequency comb-swept laser light source is 1550nm, the sweep frequency range of a single light source is 25.6nm, sweep frequency is carried out at a frequency step of 25GHz (wavelength step of 0.2 nm), the sweep frequency rate is 200KHz, and by comparing the central wavelengths of 1300nm and 1550nm, the imaging effect of 1300nm and 1550nm is almost poor, 1300nm is slightly better, and 1550nm is slightly affected by water absorption.
The main Mach-Zehnder interferometer module adopts an optical fiber type Mach-Zehnder interferometer, has a compact structure and convenient adjustment, and can ensure that interference signals of sample light and reference light are completely and efficiently detected by a detector; the calibration Mach-Zehnder interferometer module is used for calibrating interference spectrum signals in real time, and the axial resolution can be obviously improved.
And the scanning module consists of a 2D transverse scanning mechanism, a light beam collimation and focusing lens and a biological microscope. Through 2D transverse scanning, the frequency-sweeping OCT system can display an image of a cross section in the sample in real time.
The frequency-sweeping OCT is a complex system, and hardware synchronization and data acquisition are realized by a multifunctional data acquisition card, a function generator and the like which are integrated in a computer, so that 12-bit sampling points can be acquired at most.
The system is also provided with a software module based on a LabVIEW and MATLAB mixed development platform, has the characteristics of good operability, reliability and stability, and is convenient for later maintenance, function expansion and upgrading. The software module comprises time sequence control and synchronization, data acquisition and processing, vibration measurement, OCT image reconstruction and the like.
And the scanning module can add 1 path of detection light to simultaneously carry out vibration measurement on 2 points. What is needed is an improvement in part to the biomicroscope adapter and 2 nd mach-zender interferometer while also coordinating the data acquisition rate and the data processing rate.
The embodiments in the present description are described in a progressive manner, each embodiment focuses on differences from other embodiments, and the same and similar parts among the embodiments are referred to each other. The device disclosed by the embodiment corresponds to the method disclosed by the embodiment, so that the description is simple, and the relevant points can be referred to the method part for description.
The previous description of the disclosed embodiments is provided to enable any person skilled in the art to make or use the present invention. Various modifications to these embodiments will be readily apparent to those skilled in the art, and the generic principles defined herein may be applied to other embodiments without departing from the spirit or scope of the invention. Thus, the present invention is not intended to be limited to the embodiments shown herein but is to be accorded the widest scope consistent with the principles and novel features disclosed herein.
Claims (6)
1. A volumetric optical coherence tomography vibration measurement system comprising: the device comprises a light source module (1), a main Mach-Zehnder interferometer module (3), a calibration Mach-Zehnder interferometer module (2), a scanning module (4) and an acquisition control module (5);
the light source module (1) is connected with the acquisition control module (5), the main Mach-Zehnder interferometer module (3), the calibration Mach-Zehnder interferometer module (2) and the scanning module (4), the calibration Mach-Zehnder interferometer module (2) is also connected with the acquisition control module (5), the main Mach-Zehnder interferometer module (3) is connected with the acquisition control module (5) and the scanning module (4), and the scanning module (4) is also connected with the acquisition control module (5).
2. The system according to claim 1, wherein the light source module (1) comprises a positioning laser (11), an optical frequency comb-swept laser light source (12), a first broadband fiber coupler (14), a conventional swept laser light source (13), and an optical switch (15), the positioning laser (11) is connected to the main mach-zehnder interferometer module (3), the optical frequency comb-swept laser light source (12) is connected to the optical switch (15), the conventional swept laser light source (13) is connected to the first broadband fiber coupler (14), and the first broadband fiber coupler (14) is further connected to the optical switch (15) and the calibration mach-zehnder interferometer module (2).
3. The system according to claim 1, wherein the calibrated Mach-Zehnder interferometer module (2) comprises a second broadband fiber coupler (21), a first polarization controller (22), a second polarization controller (23), a first variable attenuator (24), a second variable attenuator (25), a first variable retarder (26), a second variable retarder (27), a third broadband fiber coupler (28), and a first balanced detector (29), one end of the second broadband fiber coupler (21) is connected with the light source module (1), and the other end is connected with the first balanced detector (29) through the first polarization controller (22), the first variable attenuator (24), the first variable retarder (26), and the third broadband fiber coupler (28) in sequence, the other end of the second broadband fiber coupler (21) is further connected with the first balance detector (29) sequentially through the second polarization controller (23), the second variable attenuator (25), the second variable retarder (27) and the third broadband fiber coupler (28), and the first balance detector (29) is connected with the acquisition control module (5).
4. The system according to claim 1, wherein the main mach-zehnder interferometer module (3) comprises a fourth broadband fiber coupler (31), a fiber circulator (32), a fifth broadband fiber coupler (33), a third polarization controller (34), a fourth polarization controller (35), a third variable attenuator (36), a third variable retarder (37), a sixth broadband fiber coupler (38) and a second balanced detector (39), one end of the fourth broadband fiber coupler (31) is connected with the light source module (1), the other end of the fourth broadband fiber coupler (31) is connected with the fifth broadband fiber coupler (33) through the fiber circulator (32), the fifth broadband fiber coupler (33) is connected with the scanning module (4), and the other end of the fourth broadband fiber coupler (31) is further connected with the third polarization controller (34) sequentially 34) The third variable attenuator (36), the third variable retarder (37) and the sixth broadband fiber coupler (38) are connected with the second balance detector (39), the fiber circulator (32) is further connected with the second balance detector (39) sequentially through the fourth polarization controller (35) and the sixth broadband fiber coupler (38), and the second balance detector (39) is connected with the acquisition control module (5).
5. The system according to claim 1, wherein the scanning module (4) comprises a fiber collimating mirror (41), a two-dimensional scanning galvanometer (42) and a dichroic mirror (43), the fiber collimating mirror (41) is connected with the main mach-zehnder interferometer module (3), the two-dimensional scanning galvanometer (42) is connected with the acquisition control module (5), the fiber collimating mirror (41) is optically connected with the two-dimensional scanning galvanometer (42), and the two-dimensional scanning galvanometer (42) is optically connected with the dichroic mirror (43).
6. The system according to claim 1, wherein the acquisition control module (5) comprises a computer (51), an acquisition card (52) and a function generator (53), the computer (51) is connected to the acquisition card (52) and the function generator (53), the acquisition card (52) is connected to the light source module (1), the main mach-de interferometer module (3) and the calibration mach-de interferometer module (2), and the function generator (53) is connected to the scanning module (4).
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| CN202120098686.8U CN214408662U (en) | 2021-01-14 | 2021-01-14 | Volume optical coherence tomography vibration measurement system |
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| CN202120098686.8U CN214408662U (en) | 2021-01-14 | 2021-01-14 | Volume optical coherence tomography vibration measurement system |
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