CN110967515B - Kit, reagent disk, and reagent storage device - Google Patents
Kit, reagent disk, and reagent storage device Download PDFInfo
- Publication number
- CN110967515B CN110967515B CN201811148959.4A CN201811148959A CN110967515B CN 110967515 B CN110967515 B CN 110967515B CN 201811148959 A CN201811148959 A CN 201811148959A CN 110967515 B CN110967515 B CN 110967515B
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- reagent
- kit
- handle
- reagent disk
- turntable
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
- G01N35/04—Details of the conveyor system
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
- G01N35/04—Details of the conveyor system
- G01N2035/0401—Sample carriers, cuvettes or reaction vessels
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- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
Abstract
The invention relates to a kit for circumferential arrangement on a reagent disk, comprising: the box body is borne on the reagent disk; the handle is arranged in the box body, and the orthographic projection of the handle on the reagent disk is positioned in the orthographic projection of the box body on the reagent disk in the circumferential direction of the reagent disk; wherein the handle is held to load or unload the cartridge. Through setting up the handle on the box body, the orthographic projection of handle on the reagent dish is located the box body within the orthographic projection of handle on the reagent dish, and the handle does not occupy the space on the reagent dish circumference, and when holding the handle with fingers, need not to reserve the accommodation space of finger between two adjacent box bodies, through eliminating this idle accommodation space, can realize the compact arrangement of kit on the reagent dish, under the unchangeable circumstances of reagent dish size, can bear more kits on the reagent dish.
Description
Technical Field
The invention relates to the technical field of medical instruments, in particular to a kit, a reagent disk and a reagent storage device.
Background
In immunoassays, the reagents generally comprise a plurality of components, such as the usual 2 to 5 components, including reagent components of magnetic particle reagents, labeling reagents, diluents, pretreatment solutions, etc., depending on the specific assay item. The magnetic particle reagent component commonly used in heterogeneous immunoassays, also known as solid phase reagents, require that the solid phase reagents be in a uniform suspension prior to instrument sampling. Typically, multiple reagent components for the same test item are typically packaged and stored in a single kit, which is secured to a reagent tray for access during analysis.
With the conventional reagent disk, since a plurality of reagent cartridges are closely arranged on the reagent disk in the circumferential direction thereof, a clasp hand for placing a finger is usually reserved on the reagent disk for loading and unloading the reagent cartridges on the reagent disk, but in consideration of the space occupied by the finger, the size of the reagent disk is increased in the case of loading the same number of reagent cartridges.
Disclosure of Invention
One technical problem solved by the present invention is how to achieve a compact arrangement of the kits on the reagent disk.
A kit for circumferential arrangement on a reagent disk, comprising:
the box body is borne on the reagent disk; a kind of electronic device with high-pressure air-conditioning system
The handle is arranged in the box body, and the orthographic projection of the handle on the reagent disk is positioned in the orthographic projection of the box body on the reagent disk in the circumferential direction of the reagent disk; wherein the handle is held to load or unload the cartridge.
In one embodiment, two guide plates are oppositely arranged in the box body, the handle is located in a gap between the two guide plates, and the handle can slide relative to the guide plates.
In one embodiment, the handle is provided with a first clamping plate and a second clamping plate, the first clamping plate and the second clamping plate are mutually spaced to form a positioning gap, and the guide plate is in sliding fit with the positioning gap.
In one embodiment, the guide plate is concavely formed with a limit groove on the surface of the boundary of the gap, the surface of the handle is convexly formed with a convex strip extending towards the limit groove, and the convex strip can extend into the limit groove to limit the sliding travel of the handle.
In one embodiment, the cross section of the raised strip is triangular or rectangular.
In one embodiment, the box body is ballasted on the surface of the reagent disk and is provided with a first mounting hole, the handle is provided with a second mounting hole corresponding to the first mounting hole, and the first mounting hole and the second mounting hole are used for inserting a positioning column arranged on the reagent disk.
In one embodiment, the kit further comprises a solid-phase reagent container rotationally connected with the kit body, wherein external gear teeth are arranged on the solid-phase reagent container and are used for being meshed with internal gear teeth arranged on the reagent disk.
A reagent tray for carrying a reagent kit, comprising:
the rotor comprises a turntable, partition plates and positioning columns, wherein the partition plates are arranged on the surface of the turntable at intervals along the circumferential direction, an installation gap for accommodating the reagent box is formed between two adjacent partition plates, the positioning columns are connected with the turntable and positioned in the installation gap, and the positioning columns can be inserted into the reagent box; a kind of electronic device with high-pressure air-conditioning system
And the stator is arranged around the turntable, inner gear teeth are arranged on the surface of the stator facing the rotor, and the inner gear teeth are used for being meshed with outer gear teeth arranged on the kit.
In one embodiment, the rotor further comprises an outer cylinder and an inner cylinder radially spaced apart on the turntable, the diaphragm being located between the outer cylinder and the inner cylinder; when the kit is positioned in the installation gap, both the inner wall surface of the outer cylinder and the outer wall surface of the inner cylinder can be pressed against the kit.
A reagent storage device comprising a reagent cartridge according to any one of the above and a reagent tray according to any one of the above, the reagent cartridge being carried on the reagent tray.
One technical effect of one embodiment of the present invention is: through setting up the handle on the box body, the orthographic projection of handle on the reagent dish is located the box body within the orthographic projection of handle on the reagent dish, and the handle does not occupy the space on the reagent dish circumference, and when holding the handle with fingers, need not to reserve the accommodation space of finger between two adjacent box bodies, through eliminating this idle accommodation space, can realize the compact arrangement of kit on the reagent dish, under the unchangeable circumstances of reagent dish size, can bear more kits on the reagent dish. Meanwhile, the partition plates and the positioning columns are arranged on the turntable, an installation gap for accommodating the box body is formed between the partition plates, and the reagent box can be smoothly accommodated in the installation gap through the limiting and guiding functions of the partition plates; the locating column can be inserted in the kit, and under the restriction of locating column, further make the kit correctly install in place on the carousel, prevent the jamming phenomenon, ensure the reliability that the kit loaded.
Drawings
FIG. 1 is a schematic perspective view of a kit according to an embodiment;
FIG. 2 is an exploded view of the structure of FIG. 1;
FIG. 3 is a schematic perspective view of the handle of FIG. 1;
FIG. 4 is a schematic perspective view of the case of FIG. 1;
FIG. 5 is a schematic cross-sectional view of the cartridge and handle assembly of FIG. 1;
FIG. 6 is a schematic perspective view of a reagent disk according to one embodiment;
FIG. 7 is a schematic perspective view of the reagent tray part carrying the reagent kit of FIG. 6;
fig. 8 is a perspective view of the reagent disk of fig. 6 carrying the reagent cartridge in its entirety.
Detailed Description
In order that the invention may be readily understood, a more complete description of the invention will be rendered by reference to the appended drawings. The drawings illustrate preferred embodiments of the invention. This invention may, however, be embodied in many different forms and should not be construed as limited to the embodiments set forth herein. Rather, these embodiments are provided so that this disclosure will be thorough and complete.
It will be understood that when an element is referred to as being "fixed to" another element, it can be directly on the other element or intervening elements may also be present. When an element is referred to as being "connected" to another element, it can be directly connected to the other element or intervening elements may also be present. The terms "inner", "outer", "left", "right" and the like are used herein for illustrative purposes only and do not represent the only embodiment.
Referring to fig. 1, 2 and 6, the present invention provides a reagent cartridge 10 and a reagent disk 20, the reagent cartridge 10 being arranged on the reagent disk 20 in the circumferential direction of the reagent disk 20. The kit 10 comprises a kit body 100, a handle 200 and a solid phase reagent container 300; the reagent disk 20 includes a rotor 500 and a stator 600, the rotor 500 being rotatable, and the stator 600 being stationary. The rotor 500 includes a turntable 510, a spacer 520, and a positioning post 530, wherein the turntable 510 is connected to a driving shaft 540, and the driving shaft 540 can drive the turntable 510 to rotate relative to the stator 600. The partitions 520 are disposed on the upper surface of the turntable 510 at intervals along the circumferential direction of the turntable 510, a mounting gap 521 is formed between two adjacent partitions 520, the cartridge body 100 of the cartridge 10 is accommodated in the mounting gap 521, the positioning column 530 is connected with the upper surface of the turntable 510 and is located in the mounting gap 521, and the positioning column 530 can be inserted in the entire cartridge 10.
The solid phase reagent container 300 is rotatably connected to the cartridge body 100, and external gear teeth 310 are provided on the solid phase reagent container 300. The stator 600 is disposed around the turntable 510, and an inner surface of the stator 600 facing the turntable 510 is provided with inner teeth 610, and the inner teeth 610 are engaged with the outer teeth 310 of the solid phase reagent container 300. When the whole reagent kit 10 is carried on the rotary disk 510, the reagent kit 10 can be smoothly accommodated in the mounting gap 521 by the limiting and guiding functions of the partition 520; meanwhile, the positioning column 530 is inserted into the kit 10, so that the kit 10 is further correctly mounted on the turntable 510 under the limitation of the positioning column 530, the clamping stagnation phenomenon is prevented, the loading reliability of the kit 10 is ensured, and the accurate engagement of the inner gear teeth 610 and the outer gear teeth 310 is realized.
During operation, the turntable 510 drives the reagent kit 10 to rotate around the driving shaft 540, and during the rotation process of the turntable 510, as the outer gear teeth 310 on the solid-phase reagent container 300 are meshed with the inner gear teeth 610 on the stator 600, the reagent kit 10 rotates around the central shaft of the reagent kit 10 in the revolution process of the outer gear teeth 310 and the inner gear teeth 610 around the driving shaft 540, and the suspension in the solid-phase reagent container 300 generates vortex under the combined action of revolution and rotation, so that the solid particles of the magnetic particles are uniformly suspended in the liquid, and the generation of precipitation is avoided. Of course, the kit 10 further includes the homogeneous reagent container 400, and since the homogeneous reagent container 400 is used for containing a solution, the homogeneous reagent container 400 does not have a problem of precipitation and does not need to be uniformly mixed, and thus the external gear teeth 310 are not required to be arranged on the homogeneous reagent container 400.
Referring to fig. 6-8, in some embodiments, the baffles 520 each extend radially along the turntable 510 such that the baffles 520 are radially distributed over the turntable 510. The rotor 500 further includes an outer cylinder 550 and an inner cylinder 560, the outer cylinder 550 and the inner cylinder 560 being disposed at intervals in a radial direction of the turntable 510, for example, the outer cylinder 550 is connected to an outer circumferential surface of the turntable 510, and the outer cylinder 550 protrudes from an upper surface of the turntable 510 by a set height; the inner cylinder 560 is disposed near the center of the turntable 510, and as such, the inner cylinder 560 protrudes from the upper surface of the turntable 510 by a set height; the baffle 520 is located between the outer cylinder 550 and the inner cylinder 560, and one end of the baffle 520 may be directly fixed to the inner cylinder 560, however, the other end of the baffle 520 may be directly fixed to the outer cylinder 550 or may be kept at a set distance from the outer cylinder 550. When the cartridge body 100 of the kit 10 is positioned in the mounting gap 521, the inner wall surface of the outer cylinder 550 and the outer wall surface of the inner cylinder 560 can both be pressed against the cartridge body 100, so as to further accurately position the smooth mounting of the cartridge body 100, and improve the stability and reliability of the mounting of the kit 10.
Referring to fig. 1 and 6, the handle 200 is installed in the case 100, and the case 100 can be conveniently loaded on the turntable 510 by pinching the handle 200 with fingers, and the case 100 can be conveniently unloaded from the turntable 510. In the circumferential direction of the reagent disk 20, the orthographic projection of the handle 200 on the reagent disk 20 is located within the orthographic projection of the cartridge body 100 on the reagent disk 20, so that the handle 200 does not occupy the space in the circumferential direction of the whole reagent disk 20, when the handle 200 is held by fingers, the accommodating space for fingers is not required to be reserved between two adjacent cartridge bodies 100, more reagent cartridges 10 can be carried on the turntable 510 by eliminating the idle accommodating space, and the reagent disk 510 can be provided with the same number of reagent cartridges 10 under the condition that the size of the turntable 510 is unchanged.
Referring to fig. 3 to 5, in some embodiments, two guide plates 110 are installed in the case 100, the two guide plates 110 are vertically disposed, a portion of the handle 200 is located in the gap 102 between the two guide plates 110, and the handle 200 can slide up and down in the gap 102 by a reasonable distance with respect to the guide plates 110. Specifically, for example, the handle 200 is provided with the first clamping plate 210 and the second clamping plate 220, the first clamping plate 210 and the second clamping plate 220 are spaced from each other to form the positioning gap 211, the guide plate 110 is in sliding fit with the positioning gap 211, and the first clamping plate 210 and the second clamping plate 220 are arranged to enclose the positioning gap 211, so that the handle 200 can slide up and down more accurately. Of course, in other embodiments, the sinking groove is directly formed on the surface of the handle 200, and by matching the guide plate 110 with the sinking groove, the handle 200 can be ensured to slide in the up-down direction accurately.
In some embodiments, the guide plates 110 are formed with a limit groove 120, the limit groove 120 being formed by a surface depression defining the gap 102 between the guide plates 110, it being apparent that the limit groove 120 is depressed in a direction away from the gap 102. A protrusion 230 is formed on the surface of the handle 200 in a protruding manner, the protrusion 230 extends toward the direction of the limit groove 120, and the protrusion 230 can extend into the limit groove 120. By the cooperation of the protruding strip 230 and the limiting groove 120, the sliding travel of the handle 200 can be limited. When the handle 200 is pulled up until the protrusion 230 collides with the upper side wall 121 of the limit groove 120, the handle 200 stops sliding upwards; when the handle 200 is pressed down until the protrusion 230 abuts against the lower sidewall 122 of the limit groove 120, the handle 200 stops sliding downward.
The cross section of the protruding strip 230 is triangular, the protruding strip 230 with the triangular cross section is convenient for mounting the handle 200, and the protruding strip 230 is easy to enter the limit groove 120 from the gap between the guide plates 110 under the guidance of the inclined plane on the protruding strip 230, and of course, the cross section of the protruding strip 230 can be rectangular or other shapes.
In some embodiments, the cartridge body 100 has a first mounting hole 101 formed therein, the first mounting hole 101 being positioned on a surface of the cartridge body 100 ballasted on the reagent disk 20 (i.e., on a bottom surface of the cartridge body 100), and when the reagent cartridge 10 is carried on the reagent disk 20, the positioning column 530 on the turntable 510 is inserted into the first mounting hole 101, thus facilitating the proper installation of the reagent cartridge 10. Further, a second mounting hole 201 may be formed on the handle 200, where the second mounting hole 201 corresponds to the first mounting hole 101, i.e. the second mounting hole 201 is located above the first mounting hole 101, and when the reagent kit 10 is carried on the reagent disk 20, the positioning column 530 passes through the first mounting hole 101 and is inserted into the second mounting hole 201, i.e. the positioning column 530 is simultaneously inserted into the first mounting hole 101 and the second mounting hole 201.
The invention also provides a reagent storage device comprising the reagent kit 10 and a reagent disk.
The technical features of the above-described embodiments may be arbitrarily combined, and all possible combinations of the technical features in the above-described embodiments are not described for brevity of description, however, as long as there is no contradiction between the combinations of the technical features, they should be considered as the scope of the description.
The above examples illustrate only a few embodiments of the invention, which are described in detail and are not to be construed as limiting the scope of the invention. It should be noted that it will be apparent to those skilled in the art that several variations and modifications can be made without departing from the spirit of the invention, which are all within the scope of the invention. Accordingly, the scope of protection of the present invention is to be determined by the appended claims.
Claims (10)
1. A kit for circumferential arrangement on a reagent disk, comprising:
the box body is borne on the reagent disk; a kind of electronic device with high-pressure air-conditioning system
The handle is arranged in the box body, and the orthographic projection of the handle on the reagent disk is positioned in the orthographic projection of the box body on the reagent disk in the circumferential direction of the reagent disk; wherein the handle is held to load or unload the box body;
two guide plates are oppositely arranged in the box body, the handle is positioned in a gap between the two guide plates, and the handle can slide relative to the guide plates; the handle is provided with a first clamping plate and a second clamping plate, the first clamping plate and the second clamping plate are mutually spaced to form a positioning gap, and the guide plate is in sliding fit with the positioning gap; the limiting grooves are concavely formed on the surfaces of the guide plates, which delimit the boundaries of the gaps, and the lifting handles are convexly formed with convex strips extending towards the limiting grooves, and the convex strips can extend into the limiting grooves to limit the sliding travel of the lifting handles.
2. The kit of claim 1, wherein the first splint and the second splint are rectangular.
3. The kit according to claim 1, wherein the first clamping plate and the second clamping plate forming the positioning gap are denoted as a pair of clamping plates, and the same guide plate corresponds to two of the pair of clamping plates disposed at a spacing.
4. The kit according to claim 1, wherein the cross section of the ridge is rectangular.
5. The kit according to claim 1, wherein the cross section of the convex strip is triangular.
6. The kit of claim 1, wherein the cartridge body is ballasted with a first mounting hole on the surface of the reagent disk, a second mounting hole corresponding to the first mounting hole is formed on the handle, and the first mounting hole and the second mounting hole are used for inserting a positioning column arranged on the reagent disk.
7. The kit of claim 1, further comprising a solid phase reagent container rotatably coupled to the cartridge body, the solid phase reagent container having external gear teeth disposed thereon for engagement with internal gear teeth disposed on the reagent disk.
8. A reagent storage device comprising the kit of any one of claims 1 to 7 and a reagent disk on which the kit is carried, the reagent disk comprising:
the rotor comprises a turntable, partition plates and positioning columns, wherein the partition plates are arranged on the surface of the turntable at intervals along the circumferential direction, an installation gap for accommodating the reagent box is formed between two adjacent partition plates, the positioning columns are connected with the turntable and positioned in the installation gap, and the positioning columns can be inserted into the reagent box; a kind of electronic device with high-pressure air-conditioning system
And the stator is arranged around the turntable, inner gear teeth are arranged on the surface of the stator facing the rotor, and the inner gear teeth are used for being meshed with outer gear teeth arranged on the kit.
9. The reagent storage device of claim 8, wherein the rotor further comprises an outer cylinder and an inner cylinder radially spaced apart on the turntable, the partition being located between the outer cylinder and the inner cylinder; when the kit is positioned in the installation gap, both the inner wall surface of the outer cylinder and the outer wall surface of the inner cylinder can be pressed against the kit.
10. The reagent storage device of claim 8, wherein the partitions are radially disposed on the turntable.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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CN201811148959.4A CN110967515B (en) | 2018-09-29 | 2018-09-29 | Kit, reagent disk, and reagent storage device |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
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CN201811148959.4A CN110967515B (en) | 2018-09-29 | 2018-09-29 | Kit, reagent disk, and reagent storage device |
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CN110967515A CN110967515A (en) | 2020-04-07 |
CN110967515B true CN110967515B (en) | 2023-10-20 |
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CN201811148959.4A Active CN110967515B (en) | 2018-09-29 | 2018-09-29 | Kit, reagent disk, and reagent storage device |
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Families Citing this family (1)
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CN113533762A (en) * | 2020-04-22 | 2021-10-22 | 深圳迎凯生物科技有限公司 | Reagent storage device |
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CN2334229Y (en) * | 1998-03-31 | 1999-08-25 | 乔工科技股份有限公司 | Controller for telescopic rod of trunk |
JP2004226274A (en) * | 2003-01-23 | 2004-08-12 | Olympus Corp | Reagent vessel |
CN101720216A (en) * | 2007-11-08 | 2010-06-02 | 因福皮亚有限公司 | Reagent vessel |
CN202303815U (en) * | 2011-11-03 | 2012-07-04 | 广东美的制冷设备有限公司 | Lifting handle device for air treatment equipment |
CN202909744U (en) * | 2012-11-27 | 2013-05-01 | 北京豪迈生物工程有限公司 | Kit convenient to pick and place and used for biochemical analyzer |
CN105013546A (en) * | 2015-07-03 | 2015-11-04 | 艾康生物技术(杭州)有限公司 | Biological sample reaction box |
CN204889688U (en) * | 2015-08-24 | 2015-12-23 | 黎伟文 | Modified food steamer |
CN205374474U (en) * | 2015-12-22 | 2016-07-06 | 深圳雷杜生命科学股份有限公司 | Reagent kit |
CN205562577U (en) * | 2016-02-03 | 2016-09-07 | 深圳雷杜生命科学股份有限公司 | Chemiluminescence reagent structure of twining |
CN207764239U (en) * | 2017-08-16 | 2018-08-24 | 北京普利生仪器有限公司 | Automatic checkout equipment and its reagent disc |
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2018
- 2018-09-29 CN CN201811148959.4A patent/CN110967515B/en active Active
Patent Citations (10)
Publication number | Priority date | Publication date | Assignee | Title |
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CN2334229Y (en) * | 1998-03-31 | 1999-08-25 | 乔工科技股份有限公司 | Controller for telescopic rod of trunk |
JP2004226274A (en) * | 2003-01-23 | 2004-08-12 | Olympus Corp | Reagent vessel |
CN101720216A (en) * | 2007-11-08 | 2010-06-02 | 因福皮亚有限公司 | Reagent vessel |
CN202303815U (en) * | 2011-11-03 | 2012-07-04 | 广东美的制冷设备有限公司 | Lifting handle device for air treatment equipment |
CN202909744U (en) * | 2012-11-27 | 2013-05-01 | 北京豪迈生物工程有限公司 | Kit convenient to pick and place and used for biochemical analyzer |
CN105013546A (en) * | 2015-07-03 | 2015-11-04 | 艾康生物技术(杭州)有限公司 | Biological sample reaction box |
CN204889688U (en) * | 2015-08-24 | 2015-12-23 | 黎伟文 | Modified food steamer |
CN205374474U (en) * | 2015-12-22 | 2016-07-06 | 深圳雷杜生命科学股份有限公司 | Reagent kit |
CN205562577U (en) * | 2016-02-03 | 2016-09-07 | 深圳雷杜生命科学股份有限公司 | Chemiluminescence reagent structure of twining |
CN207764239U (en) * | 2017-08-16 | 2018-08-24 | 北京普利生仪器有限公司 | Automatic checkout equipment and its reagent disc |
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