CN110237148A - A kind of Rehmannia glutinosa production technology - Google Patents
A kind of Rehmannia glutinosa production technology Download PDFInfo
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- CN110237148A CN110237148A CN201910662832.2A CN201910662832A CN110237148A CN 110237148 A CN110237148 A CN 110237148A CN 201910662832 A CN201910662832 A CN 201910662832A CN 110237148 A CN110237148 A CN 110237148A
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- rehmannia
- rehmannia glutinosa
- glutinosa
- glutinous rehmannia
- steaming
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/80—Scrophulariaceae (Figwort family)
- A61K36/804—Rehmannia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
- A61L2/0011—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
- A61L2/0029—Radiation
- A61L2/0047—Ultraviolet radiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/10—Preparation or pretreatment of starting material
- A61K2236/17—Preparation or pretreatment of starting material involving drying, e.g. sun-drying or wilting
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2202/00—Aspects relating to methods or apparatus for disinfecting or sterilising materials or objects
- A61L2202/20—Targets to be treated
- A61L2202/21—Pharmaceuticals, e.g. medicaments, artificial body parts
Abstract
The invention discloses a kind of Rehmannia glutinosa production technologies, it is characterized in that: including sorting, cleans, washing, Jiu Run, steams, is sliced, dries and packs；In sorting step, Rehmannia glutinosa is classified, keeps the glutinous rehmannia of simultaneous processing uniform in size, wine when moistening can uniform pickup yellow rice wine, can be steamed when steaming uniformly, it is inside and outside consistent, radix rehmanniae preparata pornographic movie size, thickness are uniform when slice, and the Rehmannia glutinosa quality of final production is uniform, guarantee curative effect；In steaming step, collection steams juice, and juice is sprayed on Rehmannia glutinosa again, it is therefore prevented that the loss of effective component.In slicing step, cutter is sprayed using purified water, so that piece shape is stablized, slice is not easy and cutter adhesion；This technique is also dried using a kind of prepared slices of Chinese crude drugs with novel steamer, so that the duration of entire drying process greatly shortens, the concocted time of Rehmannia glutinosa also greatly shortens therewith compared with traditional handicraft, is conducive to industrialized production.
Description
Technical field
The present invention relates to Chinese medicine manufacture fields, and in particular to a kind of Rehmannia glutinosa production technology.
Background technique
Rehmannia glutinosa is a herb.It is shone for scrophulariaceae rehmannia glutinosa plant or the rhizome of bosom celebrating glutinous rehmannia, processed steaming.Function
It cures mainly are as follows: enriching yin is enriched blood.It is few to control deficiency of Yin blood, waist knee flaccidity, Cough osteopyrexia is passed out semen, and metrorrhagia and metrostaxis, irregular menstruation is quenched one's thirst, number of urinating, ear
It is deaf, blurred vision." 1. pearl sac ": empty deficiency of enriching blood greatly, promoting blood circulation, benefiting energy.2. Wang Haogu: it is main seat and be intended to, mesh coloured glaze coloured glaze is without institute
See." 3. detailed outline ": filling out marrow, long muscle, promoting vital essence and blood genernation, tonifying five zang organs, internal injury are insufficient, promoting blood circulation, Li Er, black beard and hair, Nan Ziwu
Labor seven kinds of impairments, threatened abortion in woman's wound, irregular menorrhea, tire produces all kinds of diseases and ailments." 4. the new compilation of materia medica ": kidney nourishing water, packing marrow, sharp blood vessels are mended
Beneficial Kidney-Yin, hearing-improing and eyesight improving, dark hair crow palpus.Energy tonifying spleen-yin again, only chronic diarrhea, controls internal lesion caused by overexertion wandering arthritis, yin deficiency fever, and dry cough phlegm is coughed, shortness of breath
Syndrome characterized by dyspnea, emptiness of the stomach feel hungry, and acne demonstrate,proves no purulence of having a guilty conscience, and shin stock is ached after being ill, and postpartum navel abdomen suddenly aches, sense card yin deficiency, lossless just to close, all
The dynamic blood of kind, all liver-kidney Yin deficiencies, deficient all kinds of diseases and ailments, for the main ingredient for strengthening water.
The Rehmannia glutinosa production technology of producer currently on the market is mostly that simple nine steaming nine is shone, and preparation process is coarse, and difficult
To guarantee drug effect.
By retrieval, number of patent application is that the patent of invention of CN201810964532.5 discloses a kind of Rehmannia glutinosa purification drink
The production method of piece.Its step include cleaning, nine dryings, nine times immersion, steam for nine times with bored profit, cutting, screening, pack
To the Rehmannia glutinosa medicine materical crude slice of purification.The invention mainly uses roller medicine-washing machine to improve cleaning efficiency, past using high speed in slice link
Compound medicine cutter carries out cutting, improves the degree of automation.But the shortcomings that invention, is similarly obvious, for the juice steamed
Liquid is not given to enough attention, and the juice steamed contains more effective component, and therefore, this method, which will cause, a certain amount of to be had
Imitate the loss of ingredient；The mode that glass sunlight house dries naturally is dried so that process time is too long, is unfavorable for industrialized production；It cuts
Process processed is common cutting process, and slice is easy and cutter adhesion, influences to be sliced piece shape.
Number of patent application is that the patent of invention of CN201510815321.1 discloses a kind of process for processing Rehmannia glutinosa.
This method is first to steam radix rehmanniae recen with saturated vapor, and collect the glutinous rehmannia juice of generation, is cooled to 50~65 DEG C, presses to glutinous rehmannia
It is squeezed, then is passed through saturated vapor and is steamed and collect glutinous rehmannia juice；The Rehmannia glutinosa steamed is first dried 8~10 hours,
The bored system of glutinous rehmannia juice is added 10~16 hours, continues drying 40~50 hours.The method for the processing Rehmannia glutinosa that the invention provides obtains
Rehmannia glutinosa in, acteoside content reaches 0.040~0.057%, is significantly higher than 2010 editions Pharmacopoeias of the People's Republic of China
In 0.02% requirement, still, first, only carried out secondary steam, it is difficult to by glutinous rehmannia all steam thoroughly, glutinous rehmannia does not steam possibility
It will affect its pharmacological property and turn Wen Ping by cold and cool, influence drug effect；Its concocted time is still longer, is unfavorable for the extensive life of Rehmannia glutinosa
It produces；Cutting process is common cutting process, and slice is easy and cutter adhesion, influences to be sliced piece shape.
Summary of the invention
In order to overcome the disadvantage in background technique, a kind of reservation Rehmannia glutinosa effective component, concocted time to greatest extent is found
Short, piece shape is stable, keeps Rehmannia glutinosa drug effect significant and stable Rehmannia glutinosa production technology, and The present invention gives a kind of productions of Rehmannia glutinosa
Technique.
Process flow is as follows:
Production craft step mainly includes sorting, cleans, washing, Jiu Run, steams, is sliced, dries and packs.
1. sorting, raw material glutinous rehmannia comes from the township Jiaozhuo of " four-Huai medicine ", and there is long glutinous rehmannia processing experience and just in the place of production
Secondary process equipment, the raw material glutinous rehmannia quality stable homogeneous baked out, can guarantee the glutinous rehmannia source of goods；Peasant household is planted by the place of production again
Glutinous rehmannia is screened, glutinous rehmannia is divided into three grades, level-one is the glutinous rehmannia of per kilogram 20-40 branch, and second level is per kilogram 40-60
The glutinous rehmannia of branch, three-level are the glutinous rehmannia of per kilogram 60-80 branch, by being classified, keep the glutinous rehmannia of simultaneous processing uniform in size, energy when wine moistens
Enough uniform pickup yellow rice wine can steam uniformly when steaming, inside and outside consistent, and radix rehmanniae preparata pornographic movie size, thickness are uniform when slice, most throughout one's life
The Rehmannia glutinosa quality of production is uniform, guarantees curative effect.
2. cleaning, inspection cleaning first is carried out to scene before cleaning, the article unrelated with this variety production must not be left, through QA
Operation can be cleaned after passed examination, signature.When cleaning, the raw material glutinous rehmannia for entering factory is poured into and is cleaned on workbench, sorted
The impurity such as non-medicinal effects, stone, soil block out guarantee raw material glutinous rehmannia quality.End is cleaned, QA is submitted a report asking for and inspects for acceptance, is checked and accepted
Qualification hands over next procedure, then carries out work of clearing out a gathering place, and clears out a gathering place according to " clean post clear out a gathering place operating instruction ".It was cleaned entirely
Cheng Zhong, operator's specification, standard fill in and clean the process record of production, and record cleans overall process in detail, accomplishes have track that can seek, have
According to can look into.
3. washing first carries out inspection cleaning to scene before washing, the article unrelated with this variety production must not be left, through QA
It can washing operation after passed examination, signature.When washing, glutinous rehmannia is poured into medicine-washing machine, opens tap water and medicine-washing machine, it is right
Glutinous rehmannia carries out quick water flushing, rinses a kind of prepared slices of Chinese crude drugs tumbling-box type medicine-washing that wash device used is company oneself research and development
Device, number of patent application 201720470566.X can be rushed the silt etc. in glutinous rehmannia chill mark using the technical solution
Wash clean improves cleaning efficiency and cleaning quality.Flushing terminates, and will carry out in clean raw material glutinous rehmannia loading Turnround basket quiet
It sets, is transferred to next procedure after raw material glutinous rehmannia surface is anhydrous, then carried out according to " washing post clear out a gathering place operating instruction " clear
?.During entire washing, operator's specification, standard fill in the washing process record of production, record washing overall process in detail,
Accomplish have track that can seek, has good grounds.
4. wine moistens, selection Zhejiang Province's Guiji Shan Mountain yellow rice wine progress wine profit process, the mellow giving off a strong fragrance of Guiji Shan Mountain yellow rice wine, pure grain brewing,
The processing of Chinese medicine preferably is selected.Site inspection before wine moistens, scene must not leave the article unrelated with this variety production, through QA
It can wine profit operation after passed examination, signature.According to the dry and wet degree of glutinous rehmannia, yellow rice wine 30kg-50kg is sprayed by every 100kg glutinous rehmannia
Yellow rice wine is uniformly sprayed on to clean raw material glutinous rehmannia surface, glutinous rehmannia, which is carried out overturning, during yellow rice wine sprinkling connects glutinous rehmannia uniformly
Yellow rice wine is touched, guarantees glutinous rehmannia uniform absorption.The glutinous rehmannia that yellow rice wine sprinkling terminates to mix yellow rice wine is packed into turnover box, covers case lid progress
It stews to moisten, is all absorbed by glutinous rehmannia to yellow rice wine, hand over next procedure, prepare to steam, then according to " Jiu Run clear out a gathering place in post operating instruction "
It clears out a gathering place, and fills in record of clearing out a gathering place.Operator's specification, standard fill in the wine profit process record of production during entire wine profit, in detail
Thin record wine moistens overall process, accomplishes have track that can seek, have good grounds.
5. steaming, preceding site inspection is steamed, scene must not leave the article unrelated with this variety production, check and close through QA
Operation can be steamed after lattice, signature.The raw material glutinous rehmannia for mixing yellow rice wine thoroughly is poured into multilayer to steam in frame, each layer is uniformly spread out
It puts.Frame up end, will steam and is ready for steaming in the multi-purpose retort of frame loading, opens steam generation facility, start for the first time
Heating steams, and rises to temperature to 100 DEG C of beginning timing, steams every time 90-120 minutes, steaming temperature is maintained at 100-110 DEG C
Range, temperature is unsuitable too high or too low, and too low to steam raw material glutinous rehmannia thoroughly, temperature is excessively high preferably to cause mass efficient at shunting
It loses；During steaming, the effective component in glutinous rehmannia can be flowed out with juice, reduced curative effect of medication, steamed every time after sixty minutes, first
It opens tapping valve and releases juice, be then turned on Liquid spraying pump, force spray above the glutinous rehmannia in steamer juice, to greatest extent
Prevent the loss of glutinous rehmannia effective component.A juice is carried out during steaming every time forces spray.Pressure spray during steaming
The devices such as leaching are the Patent equipment of company: a kind of prepared slices of Chinese crude drugs with novel steamer (number of patent application:
201720468563.2).Steaming time arrives, steam off generating device, opens multi-purpose retort vent valve and is depressurized, wait press
When power tabular value is 0, multi-purpose retort door is opened, the Rehmannia glutinosa after steaming is taken out.Bleeder valve is opened, juice is deposited in into stainless steel
In turnover barrel.Rehmannia glutinosa after steaming is dried, when Rehmannia glutinosa sunning 8 at it is dry when, juice is uniformly sprayed on Rehmannia glutinosa
Surface, and Rehmannia glutinosa is back and forth overturn, it absorbs Rehmannia glutinosa more uniform, then proceedes to dry, to juice completely by Rehmannia glutinosa
After absorption, preparation steams for the second time.Rehmannia glutinosa carries out repeating to steam according to operating method is steamed above, steams, dries in the air by nine times
It shines, Rehmannia glutinosa reaches that surface, section are pitch-black shinny, and matter is moistened and soft, easy adhesion, sweet, micro- degree for having fume as accord with
Standardization.It after the completion of boiling, inspects for acceptance through QA, hands over next procedure after acceptance(check), operator is according to " steaming post to clear out a gathering place
Operating instruction " it clears out a gathering place, and fill in record of clearing out a gathering place.Operator's specification, standard, which are filled in, during entirely steaming steams process production
Record, in detail record steam overall process, accomplish have track that can seek, have good grounds.
6. slice, site inspection before being sliced, scene must not leave the article unrelated with this variety production, checks and close through QA
It can sectioning after lattice, signature.By the Rehmannia glutinosa steamed for the last time dry to 7 one-tenth it is dry (hand holds Rehmannia glutinosa flexible,
Be not easily broken) when prepare slice, open slicer, the Rehmannia glutinosa dried is appropriately poured on medicine cutter workbench and is carried out
Slice, since the viscosity of Rehmannia glutinosa is big, various types of medicine cutters are all not easy to be sliced in the market for use, Rehmannia glutinosa during cutting
With cutter adhesion, it being unable to serial section, and the radix rehmanniae preparata pornographic movie of cutting is irregular, fragment is more, therefore, the cutting device of Rehmannia glutinosa
For house journal's cutting device: a kind of prepared slices of Chinese crude drugs with novel cutting device (number of patent application: 201720468564.7), cutting
Cutter is sprayed with purified water in the process, prevents Rehmannia glutinosa and cutter adhesion, influences to be sliced piece type, slice terminates, submits a report asking for
QA inspects for acceptance, acceptance(check), hands over next procedure, operator clears out a gathering place according to " slice post clear out a gathering place operating instruction ", and fills in
It clears out a gathering place record.In entire slicing processes, operator's specification, standard fill in the slicing process record of production, and record slice in detail is complete
Process accomplishes have track that can seek, have good grounds.
7. dry, dry preceding site inspection, scene must not leave the article unrelated with this variety production, check and close through QA
It can drying process after lattice, signature.When dry, drying equipment is opened, when temperature rises to 70-80 DEG C, by the good radix rehmanniae preparata of cutting
Pornographic movie is uniformly spread out and put on and is dried in multilayer basin, in drying process, since traditional handicraft is largely in stationary state
Lower heated-air drying or sunlight with drying are dry, and dry materials degree is not uniformly single enough, are unfavorable for prepared slices of Chinese crude drugs storage, Yi Fasheng
Therefore situations such as mildew, uses house journal, company: a kind of prepared slices of Chinese crude drugs with hot-air drying unit (number of patent application:
201720468569.X), reciprocating dryer is opened, radix rehmanniae preparata pornographic movie is allowed to carry out hot air circulation drying under reciprocating state,
Make radix rehmanniae preparata pornographic movie uniform drying.Drying terminates, and is sieved as requested, removes broken medicine bits, fragment, submits a report asking for QA sampling, and QA will
Sample is sent to central laboratory, and central laboratory carries out the chemical examination of acteoside to radix rehmanniae preparata pornographic movie intermediate products according to pharmacopeia,
Examine qualification that can hand over next procedure, operator clears out a gathering place according to " dry post clear out a gathering place operating instruction ", and fills in record of clearing out a gathering place.
In entire drying process, operator's specification, standard fill in the drying process record of production, record dry overall process in detail, accomplish
There is track that can seek, have good grounds.
8. packaging, site inspection before packing, scene must not leave the article unrelated with this variety production, checks and close through QA
It can packaging operation after lattice, signature.When packaging, first radix rehmanniae preparata pornographic movie is inactivated by ultraviolet-sterilization, then by Rehmannia glutinosa to be packaged
Piece is poured into packing work platform in right amount every time and carries out weighing and bagging according to batch packaging directive packing specification, finds in packaging process different
Object sorts in time.Packaging terminates, and submits a report asking for QA sampling, and QA send radix rehmanniae preparata pornographic movie sample to central laboratory, central laboratory according to
The Pharmacopoeia of the People's Republic of China one Rehmannia glutinosa quality standard of version in 2015 examines project to carry out one-hundred-percent inspection, and it is qualified to examine,
Radix rehmanniae preparata pornographic movie can be packed product and meet at warehouse for finished product, operator clears out a gathering place according to " packaging post clear out a gathering place operating instruction ", and fills out
Write script holder's record clearly.In packaging process, operator's specification, standard fill in the packaging process record of production, and record packs full mistake in detail
Journey accomplishes have track that can seek, have good grounds.
Compared with prior art, the invention has the benefit that
1. being classified in sorting step to Rehmannia glutinosa, keep the glutinous rehmannia of simultaneous processing uniform in size, wine can uniformly be inhaled when moistening
Yellow rice wine is received, can be steamed when steaming uniformly, inside and outside consistent, radix rehmanniae preparata pornographic movie size, thickness are uniform when slice, the radix rehmanniae preparata of final production
Yellow quality is uniform, guarantees curative effect.
2. collection steams juice, and juice is sprayed on Rehmannia glutinosa again, it is therefore prevented that effective component in steaming step
Loss.
3. being sprayed using purified water to cutter in slicing step, so that piece shape is stablized, slice is not easy viscous with cutter
Even.
4. being dried using a kind of prepared slices of Chinese crude drugs with novel steamer, so that the duration of entire drying process is big
It is big to shorten, it is conducive to industrialized production.
5. inactivating using ultraviolet-sterilization, the period of storage of Rehmannia glutinosa is extended.
Specific embodiment
The present invention will be described combined with specific embodiments below.Embodiment is only explanation of the invention, rather than is limited.
Embodiment 1
A kind of Rehmannia glutinosa production technology is as follows:
1. sorting, raw material glutinous rehmannia comes from the township Jiaozhuo of " four-Huai medicine ", and there is long glutinous rehmannia processing experience in the place of production and adds for the first time
Construction equipment, the raw material glutinous rehmannia quality stable homogeneous baked out, can guarantee the glutinous rehmannia source of goods；Peasant household is planted over the ground by the place of production again
Huang is screened, and glutinous rehmannia is divided into three grades, level-one is the glutinous rehmannia of per kilogram 20-40 branch, and second level is per kilogram 40-60 branch
Glutinous rehmannia, three-level are the glutinous rehmannia of per kilogram 60-80 branch.
2. cleaning, inspection cleaning first is carried out to scene before cleaning, the article unrelated with this variety production must not be left, through QA
Operation can be cleaned after passed examination, signature.When cleaning, the raw material glutinous rehmannia for entering factory is poured into and is cleaned on workbench, sorted
The impurity such as non-medicinal effects, stone, soil block out guarantee raw material glutinous rehmannia quality.End is cleaned, QA is submitted a report asking for and inspects for acceptance, is checked and accepted
Qualification hands over next procedure, then carries out work of clearing out a gathering place, and clears out a gathering place according to " clean post clear out a gathering place operating instruction ".It was cleaned entirely
Cheng Zhong, operator's specification, standard fill in and clean the process record of production, and record cleans overall process in detail, accomplishes have track that can seek, have
According to can look into.
3. washing first carries out inspection cleaning to scene before washing, the article unrelated with this variety production must not be left, through QA
It can washing operation after passed examination, signature.When washing, glutinous rehmannia is poured into medicine-washing machine, opens tap water and medicine-washing machine, it is right
Glutinous rehmannia carries out quick water flushing, rinses a kind of prepared slices of Chinese crude drugs tumbling-box type medicine-washing that wash device used is company oneself research and development
Device, number of patent application 201720470566.X can be rushed the silt etc. in glutinous rehmannia chill mark using the technical solution
Wash clean improves cleaning efficiency and cleaning quality.Flushing terminates, and will carry out in clean raw material glutinous rehmannia loading Turnround basket quiet
It sets, is transferred to next procedure after raw material glutinous rehmannia surface is anhydrous, then carried out according to " washing post clear out a gathering place operating instruction " clear
?.During entire washing, operator's specification, standard fill in the washing process record of production, record washing overall process in detail,
Accomplish have track that can seek, has good grounds.
4. wine moistens, selection Zhejiang Province's Guiji Shan Mountain yellow rice wine progress wine profit process, the mellow giving off a strong fragrance of Guiji Shan Mountain yellow rice wine, pure grain brewing,
The processing of Chinese medicine preferably is selected.Site inspection before wine moistens, scene must not leave the article unrelated with this variety production, through QA
It can wine profit operation after passed examination, signature.It, will be yellow by every 100kg glutinous rehmannia sprinkling yellow rice wine 30kg according to the dry and wet degree of glutinous rehmannia
Wine is uniformly sprayed on clean raw material glutinous rehmannia surface, and glutinous rehmannia, which is carried out overturning, during yellow rice wine sprinkling makes glutinous rehmannia uniformly contact Huang
Wine guarantees glutinous rehmannia uniform absorption.The glutinous rehmannia that yellow rice wine sprinkling terminates to mix yellow rice wine is packed into turnover box, covers case lid and is boiled in a covered pot over a slow fire
Profit, is all absorbed by glutinous rehmannia to yellow rice wine, hands over next procedure, prepares to steam, then clearly according to " Jiu Run clear out a gathering place in post operating instruction "
, and fill in record of clearing out a gathering place.Operator's specification, standard fill in the wine profit process record of production during entire wine profit, in detail
It records wine and moistens overall process, accomplish have track that can seek, have good grounds.
5. steaming, preceding site inspection is steamed, scene must not leave the article unrelated with this variety production, check and close through QA
Operation can be steamed after lattice, signature.The raw material glutinous rehmannia for mixing yellow rice wine thoroughly is poured into multilayer to steam in frame, each layer is uniformly spread out
It puts.Frame up end, will steam and is ready for steaming in the multi-purpose retort of frame loading, opens steam generation facility, start for the first time
Heating steams, and rises to temperature to 100 DEG C of beginning timing, steams every time 90 minutes, steaming temperature is maintained at 100 DEG C, and temperature is not
Preferably too high or too low, too low to steam raw material glutinous rehmannia thoroughly, temperature is excessively high preferably to cause mass efficient ingredients from lossing；Steam process
In, the effective component in glutinous rehmannia can be flowed out with juice, reduced curative effect of medication, steamed after sixty minutes every time, first open bleeder valve
Door releases juice, is then turned on Liquid spraying pump, forces spray above the glutinous rehmannia in steamer juice, prevents glutinous rehmannia from having to greatest extent
Imitate the loss of ingredient.A juice is carried out during steaming every time forces spray.During steaming pressure spray etc. devices be
A kind of Patent equipment: the prepared slices of Chinese crude drugs novel steamer (number of patent application: 201720468563.2).Steaming time arrives, and closes
Steam generation facility is closed, multi-purpose retort vent valve is opened and is depressurized, when pressure tabular value is 0, opens multi-purpose retort door,
Take out the Rehmannia glutinosa after steaming.Bleeder valve is opened, juice is deposited in stainless steel turnover barrel.Rehmannia glutinosa after steaming carries out
Sunning, when Rehmannia glutinosa sunning 8 at it is dry when, juice is uniformly sprayed on to Rehmannia glutinosa surface, and back and forth overturn Rehmannia glutinosa, makes radix rehmanniae preparata
Huang absorption is more uniform, then proceedes to dry, and after juice is absorbed by Rehmannia glutinosa completely, preparation steams for the second time.Rehmannia glutinosa is pressed
It carrying out repeating to steam according to operating method is steamed above, steams, dries by nine times, it is pitch-black shinny that Rehmannia glutinosa reaches surface, section,
Matter is moistened and soft, easy adhesion, sweet, micro- degree for having fume as comply with standard.After the completion of boiling, inspect for acceptance through QA,
Hand over next procedure after acceptance(check), operator clears out a gathering place according to " steam post clear out a gathering place operating instruction ", and fills in record of clearing out a gathering place.It is whole
It is a steam during operator specification, standard fill in and steam the process record of production, in detail record steam overall process, accomplish there is track
It can seek, have good grounds.
6. slice, site inspection before being sliced, scene must not leave the article unrelated with this variety production, checks and close through QA
It can sectioning after lattice, signature.By the Rehmannia glutinosa steamed for the last time dry to 7 one-tenth it is dry (hand holds Rehmannia glutinosa flexible,
Be not easily broken) when prepare slice, open slicer, the Rehmannia glutinosa dried is appropriately poured on medicine cutter workbench and is carried out
Slice, the cutting device of Rehmannia glutinosa are a kind of house journal's cutting device: the novel cutting device (patent application of prepared slices of Chinese crude drugs
Number: 201720468564.7), cutting during cutter with purified water is sprayed, prevent Rehmannia glutinosa and cutter adhesion, influenced
It is sliced piece type, slice terminates, submits a report asking for QA and inspect for acceptance, acceptance(check), hands over next procedure, operator is according to " slice post is clear
Field operating instruction " it clears out a gathering place, and fill in record of clearing out a gathering place.In entire slicing processes, operator's specification, standard fill in slicing process life
Record, in detail record slice overall process are produced, accomplishes have track that can seek, have good grounds.
7. dry, dry preceding site inspection, scene must not leave the article unrelated with this variety production, check and close through QA
It can drying process after lattice, signature.When dry, drying equipment is opened, when temperature rises to 70 DEG C, by the good Rehmannia glutinosa of cutting
Piece is uniformly spread out and put on and is dried in multilayer basin, in drying process, uses house journal, company: a kind of prepared slices of Chinese crude drugs use
Hot-air drying unit (number of patent application: 201720468569.X) opens reciprocating dryer, allows radix rehmanniae preparata pornographic movie reciprocating
It is dry that hot air circulation is carried out under state, makes radix rehmanniae preparata pornographic movie uniform drying.Drying terminates, and is sieved as requested, removes broken medicine
Bits, fragment submit a report asking for QA sampling, and QA send sample to central laboratory, and central laboratory is to radix rehmanniae preparata pornographic movie intermediate products according to medicine
Allusion quotation carries out the chemical examination of acteoside, examines qualification that can hand over next procedure, operator is according to " dry post, which is cleared out a gathering place, operates rule
Journey " it clears out a gathering place, and fill in record of clearing out a gathering place.In entire drying process, operator's specification, standard fill in the drying process record of production,
Dry overall process is recorded in detail, accomplishes have track that can seek, have good grounds.
8. packaging, site inspection before packing, scene must not leave the article unrelated with this variety production, checks and close through QA
It can packaging operation after lattice, signature.When packaging, first Rehmannia glutinosa medicine materical crude slice is inactivated by ultraviolet-sterilization, then by radix rehmanniae preparata to be packaged
Pornographic movie is poured into packing work platform in right amount every time and carries out weighing and bagging according to batch packaging directive packing specification, finds in packaging process
Foreign matter sorts in time.Packaging terminates, and submits a report asking for QA sampling, and QA send radix rehmanniae preparata pornographic movie sample to central laboratory, and central laboratory presses
It examines project to carry out one-hundred-percent inspection according to the Pharmacopoeia of the People's Republic of China one Rehmannia glutinosa quality standard of version in 2015, examines and close
Radix rehmanniae preparata pornographic movie can be packed product and meet at warehouse for finished product by lattice, and operator clears out a gathering place according to " packaging post clear out a gathering place operating instruction ", and
Fill in record of clearing out a gathering place.In packaging process, operator's specification, standard fill in the packaging process record of production, and record packaging in detail is complete
Process accomplishes have track that can seek, have good grounds.
Embodiment 2
A kind of Rehmannia glutinosa production technology is as follows:
1. sorting, raw material glutinous rehmannia comes from the township Jiaozhuo of " four-Huai medicine ", and there is long glutinous rehmannia processing experience in the place of production and adds for the first time
Construction equipment, the raw material glutinous rehmannia quality stable homogeneous baked out, can guarantee the glutinous rehmannia source of goods；Peasant household is planted over the ground by the place of production again
Huang is screened, and glutinous rehmannia is divided into three grades, level-one is the glutinous rehmannia of per kilogram 20-40 branch, and second level is per kilogram 40-60 branch
Glutinous rehmannia, three-level are the glutinous rehmannia of per kilogram 60-80 branch.
2. cleaning, inspection cleaning first is carried out to scene before cleaning, the article unrelated with this variety production must not be left, through QA
Operation can be cleaned after passed examination, signature.When cleaning, the raw material glutinous rehmannia for entering factory is poured into and is cleaned on workbench, sorted
The impurity such as non-medicinal effects, stone, soil block out guarantee raw material glutinous rehmannia quality.End is cleaned, QA is submitted a report asking for and inspects for acceptance, is checked and accepted
Qualification hands over next procedure, then carries out work of clearing out a gathering place, and clears out a gathering place according to " clean post clear out a gathering place operating instruction ".It was cleaned entirely
Cheng Zhong, operator's specification, standard fill in and clean the process record of production, and record cleans overall process in detail, accomplishes have track that can seek, have
According to can look into.
3. washing first carries out inspection cleaning to scene before washing, the article unrelated with this variety production must not be left, through QA
It can washing operation after passed examination, signature.When washing, glutinous rehmannia is poured into medicine-washing machine, opens tap water and medicine-washing machine, it is right
Glutinous rehmannia carries out quick water flushing, rinses a kind of prepared slices of Chinese crude drugs tumbling-box type medicine-washing that wash device used is company oneself research and development
Device, number of patent application 201720470566.X can be rushed the silt etc. in glutinous rehmannia chill mark using the technical solution
Wash clean improves cleaning efficiency and cleaning quality.Flushing terminates, and will carry out in clean raw material glutinous rehmannia loading Turnround basket quiet
It sets, is transferred to next procedure after raw material glutinous rehmannia surface is anhydrous, then carried out according to " washing post clear out a gathering place operating instruction " clear
?.During entire washing, operator's specification, standard fill in the washing process record of production, record washing overall process in detail,
Accomplish have track that can seek, has good grounds.
4. wine moistens, selection Zhejiang Province's Guiji Shan Mountain yellow rice wine progress wine profit process, the mellow giving off a strong fragrance of Guiji Shan Mountain yellow rice wine, pure grain brewing,
The processing of Chinese medicine preferably is selected.Site inspection before wine moistens, scene must not leave the article unrelated with this variety production, through QA
It can wine profit operation after passed examination, signature.It, will be yellow by every 100kg glutinous rehmannia sprinkling yellow rice wine 50kg according to the dry and wet degree of glutinous rehmannia
Wine is uniformly sprayed on clean raw material glutinous rehmannia surface, and glutinous rehmannia, which is carried out overturning, during yellow rice wine sprinkling makes glutinous rehmannia uniformly contact Huang
Wine guarantees glutinous rehmannia uniform absorption.The glutinous rehmannia that yellow rice wine sprinkling terminates to mix yellow rice wine is packed into turnover box, covers case lid and is boiled in a covered pot over a slow fire
Profit, is all absorbed by glutinous rehmannia to yellow rice wine, hands over next procedure, prepares to steam, then clearly according to " Jiu Run clear out a gathering place in post operating instruction "
, and fill in record of clearing out a gathering place.Operator's specification, standard fill in the wine profit process record of production during entire wine profit, in detail
It records wine and moistens overall process, accomplish have track that can seek, have good grounds.
5. steaming, preceding site inspection is steamed, scene must not leave the article unrelated with this variety production, check and close through QA
Operation can be steamed after lattice, signature.The raw material glutinous rehmannia for mixing yellow rice wine thoroughly is poured into multilayer to steam in frame, each layer is uniformly spread out
It puts.Frame up end, will steam and is ready for steaming in the multi-purpose retort of frame loading, opens steam generation facility, start for the first time
Heating steams, and rises to temperature to 100 DEG C of beginning timing, steams every time 120 minutes, steaming temperature is maintained at 110 DEG C, and temperature is not
Preferably too high or too low, too low to steam raw material glutinous rehmannia thoroughly, temperature is excessively high preferably to cause mass efficient ingredients from lossing；Steam process
In, the effective component in glutinous rehmannia can be flowed out with juice, reduced curative effect of medication, steamed after sixty minutes every time, first open bleeder valve
Door releases juice, is then turned on Liquid spraying pump, forces spray above the glutinous rehmannia in steamer juice, prevents glutinous rehmannia from having to greatest extent
Imitate the loss of ingredient.A juice is carried out during steaming every time forces spray.During steaming pressure spray etc. devices be
A kind of Patent equipment: the prepared slices of Chinese crude drugs novel steamer (number of patent application: 201720468563.2).Steaming time arrives, and closes
Steam generation facility is closed, multi-purpose retort vent valve is opened and is depressurized, when pressure tabular value is 0, opens multi-purpose retort door,
Take out the Rehmannia glutinosa after steaming.Bleeder valve is opened, juice is deposited in stainless steel turnover barrel.Rehmannia glutinosa after steaming carries out
Sunning, when Rehmannia glutinosa sunning 8 at it is dry when, juice is uniformly sprayed on to Rehmannia glutinosa surface, and back and forth overturn Rehmannia glutinosa, makes radix rehmanniae preparata
Huang absorption is more uniform, then proceedes to dry, and after juice is absorbed by Rehmannia glutinosa completely, preparation steams for the second time.Rehmannia glutinosa is pressed
It carrying out repeating to steam according to operating method is steamed above, steams, dries by nine times, it is pitch-black shinny that Rehmannia glutinosa reaches surface, section,
Matter is moistened and soft, easy adhesion, sweet, micro- degree for having fume as comply with standard.After the completion of boiling, inspect for acceptance through QA,
Hand over next procedure after acceptance(check), operator clears out a gathering place according to " steam post clear out a gathering place operating instruction ", and fills in record of clearing out a gathering place.It is whole
It is a steam during operator specification, standard fill in and steam the process record of production, in detail record steam overall process, accomplish there is track
It can seek, have good grounds.
6. slice, site inspection before being sliced, scene must not leave the article unrelated with this variety production, checks and close through QA
It can sectioning after lattice, signature.By the Rehmannia glutinosa steamed for the last time dry to 7 one-tenth it is dry (hand holds Rehmannia glutinosa flexible,
Be not easily broken) when prepare slice, open slicer, the Rehmannia glutinosa dried is appropriately poured on medicine cutter workbench and is carried out
Slice, the cutting device of Rehmannia glutinosa are a kind of house journal's cutting device: the novel cutting device (patent application of prepared slices of Chinese crude drugs
Number: 201720468564.7), cutting during cutter with purified water is sprayed, prevent Rehmannia glutinosa and cutter adhesion, influenced
It is sliced piece type, slice terminates, submits a report asking for QA and inspect for acceptance, acceptance(check), hands over next procedure, operator is according to " slice post is clear
Field operating instruction " it clears out a gathering place, and fill in record of clearing out a gathering place.In entire slicing processes, operator's specification, standard fill in slicing process life
Record, in detail record slice overall process are produced, accomplishes have track that can seek, have good grounds.
7. dry, dry preceding site inspection, scene must not leave the article unrelated with this variety production, check and close through QA
It can drying process after lattice, signature.When dry, drying equipment is opened, when temperature rises to 80 DEG C, by the good Rehmannia glutinosa of cutting
Piece is uniformly spread out and put on and is dried in multilayer basin, in drying process, uses house journal, company: a kind of prepared slices of Chinese crude drugs use
Hot-air drying unit (number of patent application: 201720468569.X) opens reciprocating dryer, allows radix rehmanniae preparata pornographic movie reciprocating
It is dry that hot air circulation is carried out under state, makes radix rehmanniae preparata pornographic movie uniform drying.Drying terminates, and is sieved as requested, removes broken medicine
Bits, fragment submit a report asking for QA sampling, and QA send sample to central laboratory, and central laboratory is to radix rehmanniae preparata pornographic movie intermediate products according to medicine
Allusion quotation carries out the chemical examination of acteoside, examines qualification that can hand over next procedure, operator is according to " dry post, which is cleared out a gathering place, operates rule
Journey " it clears out a gathering place, and fill in record of clearing out a gathering place.In entire drying process, operator's specification, standard fill in the drying process record of production,
Dry overall process is recorded in detail, accomplishes have track that can seek, have good grounds.
8. packaging, site inspection before packing, scene must not leave the article unrelated with this variety production, checks and close through QA
It can packaging operation after lattice, signature.When packaging, first Rehmannia glutinosa medicine materical crude slice is inactivated by ultraviolet-sterilization, then by radix rehmanniae preparata to be packaged
Pornographic movie is poured into packing work platform in right amount every time and carries out weighing and bagging according to batch packaging directive packing specification, finds in packaging process
Foreign matter sorts in time.Packaging terminates, and submits a report asking for QA sampling, and QA send radix rehmanniae preparata pornographic movie sample to central laboratory, and central laboratory presses
It examines project to carry out one-hundred-percent inspection according to the Pharmacopoeia of the People's Republic of China one Rehmannia glutinosa quality standard of version in 2015, examines and close
Radix rehmanniae preparata pornographic movie can be packed product and meet at warehouse for finished product by lattice, and operator clears out a gathering place according to " packaging post clear out a gathering place operating instruction ", and
Fill in record of clearing out a gathering place.In packaging process, operator's specification, standard fill in the packaging process record of production, and record packaging in detail is complete
Process accomplishes have track that can seek, have good grounds.
Embodiment 3
A kind of Rehmannia glutinosa production technology is as follows:
1. sorting, raw material glutinous rehmannia comes from the township Jiaozhuo of " four-Huai medicine ", and there is long glutinous rehmannia processing experience in the place of production and adds for the first time
Construction equipment, the raw material glutinous rehmannia quality stable homogeneous baked out, can guarantee the glutinous rehmannia source of goods；Peasant household is planted over the ground by the place of production again
Huang is screened, and glutinous rehmannia is divided into three grades, level-one is the glutinous rehmannia of per kilogram 20-40 branch, and second level is per kilogram 40-60 branch
Glutinous rehmannia, three-level are the glutinous rehmannia of per kilogram 60-80 branch.
2. cleaning, inspection cleaning first is carried out to scene before cleaning, the article unrelated with this variety production must not be left, through QA
Operation can be cleaned after passed examination, signature.When cleaning, the raw material glutinous rehmannia for entering factory is poured into and is cleaned on workbench, sorted
The impurity such as non-medicinal effects, stone, soil block out guarantee raw material glutinous rehmannia quality.End is cleaned, QA is submitted a report asking for and inspects for acceptance, is checked and accepted
Qualification hands over next procedure, then carries out work of clearing out a gathering place, and clears out a gathering place according to " clean post clear out a gathering place operating instruction ".It was cleaned entirely
Cheng Zhong, operator's specification, standard fill in and clean the process record of production, and record cleans overall process in detail, accomplishes have track that can seek, have
According to can look into.
3. washing first carries out inspection cleaning to scene before washing, the article unrelated with this variety production must not be left, through QA
It can washing operation after passed examination, signature.When washing, glutinous rehmannia is poured into medicine-washing machine, opens tap water and medicine-washing machine, it is right
Glutinous rehmannia carries out quick water flushing, rinses a kind of prepared slices of Chinese crude drugs tumbling-box type medicine-washing that wash device used is company oneself research and development
Device, number of patent application 201720470566.X can be rushed the silt etc. in glutinous rehmannia chill mark using the technical solution
Wash clean improves cleaning efficiency and cleaning quality.Flushing terminates, and will carry out in clean raw material glutinous rehmannia loading Turnround basket quiet
It sets, is transferred to next procedure after raw material glutinous rehmannia surface is anhydrous, then carried out according to " washing post clear out a gathering place operating instruction " clear
?.During entire washing, operator's specification, standard fill in the washing process record of production, record washing overall process in detail,
Accomplish have track that can seek, has good grounds.
4. wine moistens, selection Zhejiang Province's Guiji Shan Mountain yellow rice wine progress wine profit process, the mellow giving off a strong fragrance of Guiji Shan Mountain yellow rice wine, pure grain brewing,
The processing of Chinese medicine preferably is selected.Site inspection before wine moistens, scene must not leave the article unrelated with this variety production, through QA
It can wine profit operation after passed examination, signature.It, will be yellow by every 100kg glutinous rehmannia sprinkling yellow rice wine 40kg according to the dry and wet degree of glutinous rehmannia
Wine is uniformly sprayed on clean raw material glutinous rehmannia surface, and glutinous rehmannia, which is carried out overturning, during yellow rice wine sprinkling makes glutinous rehmannia uniformly contact Huang
Wine guarantees glutinous rehmannia uniform absorption.The glutinous rehmannia that yellow rice wine sprinkling terminates to mix yellow rice wine is packed into turnover box, covers case lid and is boiled in a covered pot over a slow fire
Profit, is all absorbed by glutinous rehmannia to yellow rice wine, hands over next procedure, prepares to steam, then clearly according to " Jiu Run clear out a gathering place in post operating instruction "
, and fill in record of clearing out a gathering place.Operator's specification, standard fill in the wine profit process record of production during entire wine profit, in detail
It records wine and moistens overall process, accomplish have track that can seek, have good grounds.
5. steaming, preceding site inspection is steamed, scene must not leave the article unrelated with this variety production, check and close through QA
Operation can be steamed after lattice, signature.The raw material glutinous rehmannia for mixing yellow rice wine thoroughly is poured into multilayer to steam in frame, each layer is uniformly spread out
It puts.Frame up end, will steam and is ready for steaming in the multi-purpose retort of frame loading, opens steam generation facility, start for the first time
Heating steams, and rises to temperature to 100 DEG C of beginning timing, steams every time 100 minutes, steaming temperature is maintained at 105 DEG C, and temperature is not
Preferably too high or too low, too low to steam raw material glutinous rehmannia thoroughly, temperature is excessively high preferably to cause mass efficient ingredients from lossing；Steam process
In, the effective component in glutinous rehmannia can be flowed out with juice, reduced curative effect of medication, steamed after sixty minutes every time, first open bleeder valve
Door releases juice, is then turned on Liquid spraying pump, forces spray above the glutinous rehmannia in steamer juice, prevents glutinous rehmannia from having to greatest extent
Imitate the loss of ingredient.A juice is carried out during steaming every time forces spray.During steaming pressure spray etc. devices be
A kind of Patent equipment: the prepared slices of Chinese crude drugs novel steamer (number of patent application: 201720468563.2).Steaming time arrives, and closes
Steam generation facility is closed, multi-purpose retort vent valve is opened and is depressurized, when pressure tabular value is 0, opens multi-purpose retort door,
Take out the Rehmannia glutinosa after steaming.Bleeder valve is opened, juice is deposited in stainless steel turnover barrel.Rehmannia glutinosa after steaming carries out
Sunning, when Rehmannia glutinosa sunning 8 at it is dry when, juice is uniformly sprayed on to Rehmannia glutinosa surface, and back and forth overturn Rehmannia glutinosa, makes radix rehmanniae preparata
Huang absorption is more uniform, then proceedes to dry, and after juice is absorbed by Rehmannia glutinosa completely, preparation steams for the second time.Rehmannia glutinosa is pressed
It carrying out repeating to steam according to operating method is steamed above, steams, dries by nine times, it is pitch-black shinny that Rehmannia glutinosa reaches surface, section,
Matter is moistened and soft, easy adhesion, sweet, micro- degree for having fume as comply with standard.After the completion of boiling, inspect for acceptance through QA,
Hand over next procedure after acceptance(check), operator clears out a gathering place according to " steam post clear out a gathering place operating instruction ", and fills in record of clearing out a gathering place.It is whole
It is a steam during operator specification, standard fill in and steam the process record of production, in detail record steam overall process, accomplish there is track
It can seek, have good grounds.
6. slice, site inspection before being sliced, scene must not leave the article unrelated with this variety production, checks and close through QA
It can sectioning after lattice, signature.By the Rehmannia glutinosa steamed for the last time dry to 7 one-tenth it is dry (hand holds Rehmannia glutinosa flexible,
Be not easily broken) when prepare slice, open slicer, the Rehmannia glutinosa dried is appropriately poured on medicine cutter workbench and is carried out
Slice, the cutting device of Rehmannia glutinosa are a kind of house journal's cutting device: the novel cutting device (patent application of prepared slices of Chinese crude drugs
Number: 201720468564.7), cutting during cutter with purified water is sprayed, prevent Rehmannia glutinosa and cutter adhesion, influenced
It is sliced piece type, slice terminates, submits a report asking for QA and inspect for acceptance, acceptance(check), hands over next procedure, operator is according to " slice post is clear
Field operating instruction " it clears out a gathering place, and fill in record of clearing out a gathering place.In entire slicing processes, operator's specification, standard fill in slicing process life
Record, in detail record slice overall process are produced, accomplishes have track that can seek, have good grounds.
7. dry, dry preceding site inspection, scene must not leave the article unrelated with this variety production, check and close through QA
It can drying process after lattice, signature.When dry, drying equipment is opened, when temperature rises to 75 DEG C, by the good Rehmannia glutinosa of cutting
Piece is uniformly spread out and put on and is dried in multilayer basin, in drying process, uses house journal, company: a kind of prepared slices of Chinese crude drugs use
Hot-air drying unit (number of patent application: 201720468569.X) opens reciprocating dryer, allows radix rehmanniae preparata pornographic movie reciprocating
It is dry that hot air circulation is carried out under state, makes radix rehmanniae preparata pornographic movie uniform drying.Drying terminates, and is sieved as requested, removes broken medicine
Bits, fragment submit a report asking for QA sampling, and QA send sample to central laboratory, and central laboratory is to radix rehmanniae preparata pornographic movie intermediate products according to medicine
Allusion quotation carries out the chemical examination of acteoside, examines qualification that can hand over next procedure, operator is according to " dry post, which is cleared out a gathering place, operates rule
Journey " it clears out a gathering place, and fill in record of clearing out a gathering place.In entire drying process, operator's specification, standard fill in the drying process record of production,
Dry overall process is recorded in detail, accomplishes have track that can seek, have good grounds.
8. packaging, site inspection before packing, scene must not leave the article unrelated with this variety production, checks and close through QA
It can packaging operation after lattice, signature.When packaging, first Rehmannia glutinosa medicine materical crude slice is inactivated by ultraviolet-sterilization, then by radix rehmanniae preparata to be packaged
Pornographic movie is poured into packing work platform in right amount every time and carries out weighing and bagging according to batch packaging directive packing specification, finds in packaging process
Foreign matter sorts in time.Packaging terminates, and submits a report asking for QA sampling, and QA send radix rehmanniae preparata pornographic movie sample to central laboratory, and central laboratory presses
It examines project to carry out one-hundred-percent inspection according to the Pharmacopoeia of the People's Republic of China one Rehmannia glutinosa quality standard of version in 2015, examines and close
Radix rehmanniae preparata pornographic movie can be packed product and meet at warehouse for finished product by lattice, and operator clears out a gathering place according to " packaging post clear out a gathering place operating instruction ", and
Fill in record of clearing out a gathering place.In packaging process, operator's specification, standard fill in the packaging process record of production, and record packaging in detail is complete
Process accomplishes have track that can seek, have good grounds.
Claims (9)
1. a kind of Rehmannia glutinosa production technology, it is characterised in that: production craft step mainly includes sorting, clean, washing, Jiu Run,
It steams, be sliced, dry and pack；
In sorting step, raw material glutinous rehmannia is classified, the same batch processing of glutinous rehmannia at the same level；
Yellow rice wine is sprayed on raw material glutinous rehmannia surface in wine profit step, when sprinkling is overturn glutinous rehmannia repeatedly；
In steaming step, the raw material glutinous rehmannia for mixing yellow rice wine thoroughly is poured into multilayer and is steamed in frame, frame loading will be steamed and steam dress
Progress is set to steam for the first time, during steaming, the juice collected is sprayed again on glutinous rehmannia, after steaming for the first time,
Rehmannia glutinosa is taken out, collects after spraying and what is occurred steams juice in clean container, the Rehmannia glutinosa after steaming carries out first
The juice of collection during sunning, is sprayed on Rehmannia glutinosa surface and overturns Rehmannia glutinosa repeatedly, continues to dry, to juice by secondary sunning
After liquid is absorbed, preparation steam for the second time, by steam, dry, spray juice, continue sunning sequence amount to repeat 9 times,
So that reach surface, section pitch-black shinny for Rehmannia glutinosa obtained, matter is moistened and soft, easy adhesion, sweet, micro- to have fume；
In slicing step, Rehmannia glutinosa is dried to 7 one-tenth and is done, open microtome, in cutting, purified water is carried out to cutter
Spray；
After drying process, sieving removes broken medicine bits, fragment, the chemical examination of acteoside is carried out according to pharmacopeia, qualified
Afterwards, next step is delivered；
In packaging step, first radix rehmanniae preparata pornographic movie to be packaged is inactivated by ultraviolet-sterilization, then carry out weighing and bagging, packaging terminates
Afterwards, project is examined to carry out all Rehmannia glutinosa according to the Pharmacopoeia of the People's Republic of China one Rehmannia glutinosa quality standard of version in 2015
It examines, it is qualified to examine, and radix rehmanniae preparata pornographic movie can be packed product and meet at warehouse for finished product.
2. a kind of Rehmannia glutinosa production technology as described in claim 1, it is characterised in that: the place of production of the raw material glutinous rehmannia is
For Jiaozhuo.
3. a kind of Rehmannia glutinosa production technology as described in claim 1, it is characterised in that: the classification mark of the raw material glutinous rehmannia
It is quasi- are as follows: level-one glutinous rehmannia is every kilogram of 20-40 branch, and second level glutinous rehmannia is every kilogram of 40-60 branch, and three-level glutinous rehmannia is every kilogram of 60-80 branch.
4. a kind of Rehmannia glutinosa production technology as described in claim 1, it is characterised in that: during the wine profit, use
Yellow rice wine is Guiji Shan Mountain yellow rice wine.
5. a kind of Rehmannia glutinosa production technology as described in claim 1, it is characterised in that: during the wine profit, sprinkling is yellow
The quality amount of wine is needed according to the decision of the quality of Rehmannia glutinosa, and every 100kg Rehmannia glutinosa needs to spray 30kg-50kg yellow rice wine.
6. a kind of Rehmannia glutinosa production technology as described in claim 1, it is characterised in that: during the sunning, work as radix rehmanniae preparata
Huang sunning to 8 one-tenth it is dry when, the juice of collection is sprayed on Rehmannia glutinosa surface.
7. a kind of Rehmannia glutinosa production technology as described in claim 1, it is characterised in that: described steams to rise to temperature
100 DEG C of beginning timing, steam 90-120 minutes, steaming temperature is maintained at 100-110 DEG C of range every time.
8. a kind of Rehmannia glutinosa production technology as described in claim 1, it is characterised in that: the juice sprayed when steaming is answered
It is sprayed when steaming 60 minutes every time.
9. a kind of Rehmannia glutinosa production technology as described in claim 1, it is characterised in that: to be dried in the drying steps
When unit temp rises to 70-80 DEG C, by the good radix rehmanniae preparata pornographic movie of cutting, uniformly spreads out and puts on and be dried in multilayer basin.
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110638901A (en) * | 2019-10-15 | 2020-01-03 | 安徽协和成药业饮片有限公司 | Preparation method of prepared rehmannia root traditional Chinese medicine decoction pieces steamed with high-pressure wine |
| CN112006913A (en) * | 2020-08-13 | 2020-12-01 | 宁夏明德中药饮片有限公司 | Preparation process for steaming prepared rehmannia root decoction pieces |
| CN115889316A (en) * | 2022-12-26 | 2023-04-04 | 安徽豪门国药股份有限公司 | Production and processing technology of prepared rehmannia root |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107213249A (en) * | 2017-04-26 | 2017-09-29 | 安徽华善堂中药饮片有限公司 | Nine steam the processing procedure method of nine-processing radix rehmanniae preparata |
| CN107929418A (en) * | 2017-10-25 | 2018-04-20 | 安徽华善堂中药饮片有限公司 | A kind of nine steam the technological process of nine-processing radix rehmanniae preparata |
-
2019
- 2019-07-22 CN CN201910662832.2A patent/CN110237148A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107213249A (en) * | 2017-04-26 | 2017-09-29 | 安徽华善堂中药饮片有限公司 | Nine steam the processing procedure method of nine-processing radix rehmanniae preparata |
| CN107929418A (en) * | 2017-10-25 | 2018-04-20 | 安徽华善堂中药饮片有限公司 | A kind of nine steam the technological process of nine-processing radix rehmanniae preparata |
Cited By (3)
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| CN110638901A (en) * | 2019-10-15 | 2020-01-03 | 安徽协和成药业饮片有限公司 | Preparation method of prepared rehmannia root traditional Chinese medicine decoction pieces steamed with high-pressure wine |
| CN112006913A (en) * | 2020-08-13 | 2020-12-01 | 宁夏明德中药饮片有限公司 | Preparation process for steaming prepared rehmannia root decoction pieces |
| CN115889316A (en) * | 2022-12-26 | 2023-04-04 | 安徽豪门国药股份有限公司 | Production and processing technology of prepared rehmannia root |
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Application publication date: 20190917 |