CN109953756A - Atrial fibrillation monitoring system and wearable device - Google Patents

Atrial fibrillation monitoring system and wearable device Download PDF

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CN109953756A
CN109953756A CN201711401597.0A CN201711401597A CN109953756A CN 109953756 A CN109953756 A CN 109953756A CN 201711401597 A CN201711401597 A CN 201711401597A CN 109953756 A CN109953756 A CN 109953756A
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atrial fibrillation
ppg
module
score
variation value
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薛奋
董喜艳
卓远
代超
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Chengdu Jikang Technology Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/24Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316Modalities, i.e. specific diagnostic methods
    • A61B5/318Heart-related electrical modalities, e.g. electrocardiography [ECG]
    • A61B5/346Analysis of electrocardiograms
    • A61B5/349Detecting specific parameters of the electrocardiograph cycle
    • A61B5/361Detecting fibrillation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/68Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6801Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • A61B5/6802Sensor mounted on worn items
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/72Signal processing specially adapted for physiological signals or for diagnostic purposes

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Abstract

The present invention provides a kind of atrial fibrillation monitoring system and wearable devices, wherein atrial fibrillation monitoring system includes PPG signal acquisition process module, PPG heart rate variability evaluation module, atrial fibrillation judgment module, atrial fibrillation logging modle, atrial fibrillation statistical module and cue module;Wherein atrial fibrillation statistical module is used for the atrial fibrillation event data based on several records, and statistics obtains the atrial fibrillation load of 0 point~24 points different periods round the clock, and cue module is for prompting user to carry out ECG detections in atrial fibrillation load maximum one or more periods.By the above-mentioned means, the present invention can be improved paroxysmal, the ECG detection probability of early stage atrial fibrillation without clinical symptoms and detection timeliness, early stage atrial fibrillation is made to be made a definite diagnosis and be controlled in time.

Description

Atrial fibrillation monitoring system and wearable device
Technical field
This application involves atrial fibrillation monitoring technical fields, in particular to based on the atrial fibrillation monitoring system of PPG analysis of heart rate variability With the wearable device being applied in the atrial fibrillation monitoring system.
Background technique
The method of traditional detection atrial fibrillation is that the electrocardio by measuring patient obtains ECG waveform figure, analyzes ECG by doctor Circadian variation in waveform diagram whether there is atrial fibrillation to diagnose.
It is purposive to detect obtained ECG waveform figure due to the randomness of part atrial fibrillation, paroxysmal and without clinical symptoms In may have no atrial fibrillation waveform, and then testee is made to be diagnosed as no atrial fibrillation, causes the state of an illness that cannot be controlled in time.
The temporal regularity that atrial fibrillation generation is obtained therefore, it is necessary to a kind of easy, lasting monitoring means, improves random battle array The ECG detection probability of hair property atrial fibrillation provides foundation to provide corresponding clinical treatment measure as early as possible.
Summary of the invention
The application discloses a kind of atrial fibrillation monitoring system and wearable device, by continue to monitor and count atrial fibrillation event when Between rule, improve paroxysmal, atrial fibrillation without clinical symptoms ECG detection probability and detection timeliness.
To achieve the above object, the application public technology scheme is as follows:
On the one hand, the disclosure proposes a kind of atrial fibrillation monitoring system, comprising: PPG signal acquisition process module, for persistently adopting Collection is monitored the PPG heartbeat signal of individual to provide PPG heartbeat signal segment;PPG heart rate variability evaluation module, for assessing The heart rate variability for stating PPG heartbeat signal segment is horizontal;Atrial fibrillation judgment module, for based on described in heart rate variability level judgement PPG heartbeat signal segment whether there is atrial fibrillation;Atrial fibrillation logging modle, for being judged presence when the PPG heartbeat signal segment When atrial fibrillation, atrial fibrillation event data is recorded, wherein the atrial fibrillation event data includes the PPG heartbeat with the atrial fibrillation event correlation The acquisition time of signal segment;Atrial fibrillation statistical module, for being based on several atrial fibrillation event datas, statistics obtains different round the clock The atrial fibrillation load of period;And cue module, for prompting the monitored individual in the maximum one or more of atrial fibrillation load Period carries out ECG detection.
Wherein, the index of the atrial fibrillation load includes the quantity of the atrial fibrillation event data.
Preferably, several atrial fibrillation event datas include the atrial fibrillation event in several days, several weeks or several months Data.
Further, the system also includes ECG signal acquisition processing modules, are used to provide the described needed for ECG detection Device.
Further, the system also includes motor message acquisition processing modules, reduce motion artifacts to room for providing Quiver judgement accuracy influence needed for device.
Wherein, above-mentioned PPG heart rate variability evaluation module includes: PPG interphase extraction unit, for believing from the PPG heartbeat It is extracted in number segment and obtains PPG inter-beat intervals sequence;Heartbeat interval variation value computing unit, for based between the PPG heartbeat Heartbeat interval variation value sequence is calculated in phase sequence;And atrial fibrillation score determination unit, for according to a preset variation value- Score mapping table calculates the heartbeat interval variation resulting accumulative atrial fibrillation score of value sequence;Wherein, the accumulative atrial fibrillation obtains Divide the index for being configured as the heart rate variability level, the atrial fibrillation judgment module is configured as the accumulative atrial fibrillation score Compared with a default score threshold, judge the PPG heartbeat signal segment with the presence or absence of atrial fibrillation according to comparison result.
Preferably, if the variation value-score mapping table be configured to include several atrial fibrillation score values and with the stove room Several interphase variation value segments of the score value that quivers mapping.
In one embodiment, the heartbeat interval variation value computing unit be configured as according to formula dINT (n)= (INT (n)/((INT (n)+INT (n-1)+INT (n-2)) -1/3) calculates the variation value of each interphase to ABS, wherein INT (n) Indicate the time interval of n-th of interphase, INT (n-1) and INT (n-2) indicate the time close to the first two interphase of n-th of interphase Interval, n >=3.
Wherein, the variation value-score mapping table is configured to include 9 interphase variation value segments, and the interphase becomes Different value [0,0.012) segment and [0.18,0.23) the atrial fibrillation score values of segment correspondence mappings is negative, [0.012,0.18) The atrial fibrillation score value of segment correspondence mappings is positive.
On the other hand, the present disclosure proposes a kind of wearable device, the wearable device includes above-mentioned atrial fibrillation monitoring system System.
Above-mentioned atrial fibrillation monitoring system prompts user to exist by continuing to monitor and counting the temporal regularity round the clock of atrial fibrillation event ECG is detected in the high atrial fibrillation load period, improve paroxysmal, atrial fibrillation without clinical symptoms ECG detection probability and detection Timeliness.
Detailed description of the invention
Fig. 1 shows the schematic diagram of an exemplary ECG heartbeat segment and PPG heartbeat segment;
Fig. 2 shows the schematic diagrames of the comprising modules of an exemplary atrial fibrillation monitoring system;
Fig. 3 shows the schematic diagram of the comprising modules of an exemplary atrial fibrillation monitoring system;
Fig. 4 shows the schematic diagram of the component units of an exemplary PPG heart rate variability evaluation module;
Fig. 5 shows the schematic diagram of an exemplary atrial fibrillation monitoring systematic difference configuration;
Fig. 6 shows the schematic diagram of an exemplary atrial fibrillation monitoring systematic difference configuration;
Fig. 7 shows the schematic diagram of an exemplary atrial fibrillation monitoring systematic difference configuration.
Specific embodiment
To make the object, technical solutions and advantages of the present invention clearer, below in conjunction with attached drawing to embodiment party of the present invention Formula is described in further detail.
When atrial fibrillation, palmic rate is not only more faster than normal heartbeat, but also absolutely irregular, and atrium loses effective contraction Function.PPG (photoplethysmography) heart rate sensor due to it is convenient, simplify and be widely used in wearable device Continuous monitor heart rate.In general, since PPG heart rate and the ECG rhythm and pace of moving things are there are correspondence (referring to Fig. 1), it can be by continuously supervising It surveys PPG heart rate and analyzes the generation that PPG heart rate variability level carrys out monitoring and warning atrial fibrillation.
According to a kind of exemplary atrial fibrillation monitoring system 200 of the disclosure, as shown in Fig. 2, including PPG signal acquisition process module 202, PPG heart rate variability evaluation modules 204, atrial fibrillation judgment module 206, atrial fibrillation logging modle 208, atrial fibrillation statistical module 210, with And cue module 212.
Wherein, PPG signal acquisition process module 202 is monitored the PPG heartbeat signal of individual for continuous collecting to provide Detected PPG heartbeat signal segment.For example, PPG signal acquisition process module can configure PPG photoelectric sensor and PPG signal Logic unit is handled, and the PPG signal processing logic unit can be used for that the PPG heartbeat signal is carried out at noise reduction and amplification Reason.
PPG heart rate variability evaluation module 204, the heart rate variability for assessing the PPG heartbeat signal segment is horizontal, example Such as, the heart rate variability level can standard deviation by several heartbeat interval in the PPG heartbeat signal segment, adjacent heartbeat The indexs such as the standard deviation of the difference of interphase indicate.
Atrial fibrillation judgment module 206, for judging the PPG heartbeat signal based on the index value of the heart rate variability level Segment whether there is atrial fibrillation, for example, threshold method can be used by the index value of the heart rate variability level and a preset index threshold Value is compared, and judges the PPG heartbeat signal piece when the index value of the heart rate variability level is greater than the metrics-thresholds There are atrial fibrillations for section.
Atrial fibrillation logging modle 208 records atrial fibrillation thing for being judged there are when atrial fibrillation when the PPG heartbeat signal segment Number of packages evidence, for example, record and the PPG heartbeat signal segment of atrial fibrillation event correlation acquisition time (time point acquired in real time), with The data such as the time span of PPG heartbeat signal segment of atrial fibrillation event correlation.
Atrial fibrillation statistical module 210, several atrial fibrillation event datas for being recorded based on atrial fibrillation logging modle 208, statistics Obtain the atrial fibrillation load of different periods between 0 point~24 points.For example, integral point atrial fibrillation hourly is negative between 0 point~24 points of statistics Lotus.Wherein, the index of the atrial fibrillation load can indicate that wherein atrial fibrillation duration can pass through PPG heartbeat by the atrial fibrillation duration accumulated The duration data of signal segment provide indirectly.Preferably, the index of the atrial fibrillation load can also be by the atrial fibrillation event number According to quantity indicate.Preferably, several days several atrial fibrillation event datas that can be recorded based on atrial fibrillation logging modle 208, The quantity of the atrial fibrillation event data of identical period between daily 0 point~24 points is added up, obtains based on weekly data statistics, be based on Month data statistics or based on atrial fibrillation power load distributing round the clock between year according to statistics 0 point~24 points.
Cue module 212, for it is being counted based on aforementioned day, Zhou Tongji's or the moon statistics 0 point~24 points between The temporal regularity of atrial fibrillation power load distributing prompts the monitored individual to carry out in atrial fibrillation load maximum one or more periods ECG detection.Illustratively, monitored individual by the portable ECG acquisition device except system 200 or can go to medical treatment The ECG detection device that mechanism is provided by medical institutions the atrial fibrillation load maximum one or more periods carry out it is primary or Multiple ECG acquisition testing.
Preferably, atrial fibrillation monitoring system 200 further includes motor message acquisition processing module 214, for example, motor message acquires Processing module 214 can be configured to include the motion sensors such as acceleration transducer, gyro sensor and corresponding motor message Handle logic unit.When motor message is more than certain threshold value, PPG signal acquisition process module PPG heartbeat signal collected It will receive the pollution of motion artifacts, contaminated PPG heartbeat signal cannot provide the PPG heart that can carry out heart rate variability horizontal analysis It fights signal segment, in an exemplary embodiment, atrial fibrillation judgment module 210 may determine that the period that the motor message occurs Interior no atrial fibrillation.
According to a kind of exemplary atrial fibrillation monitoring system 300 of the disclosure, as shown in figure 3, further including ECG signal acquisition process mould Block 316, wherein system 300 is similar with the system of previous embodiment 200 in many aspects, and similar module passes through similar mark It number is indicated.
Device needed for ECG signal acquisition processing module 316 is used to provide ECG detection above-mentioned.For example, ECG signal is adopted Collection processing module 316 is configurable to the ECG acquisition electrode and its signal processing logic unit of measurement both hands circuit electrocardiosignal. Wherein, ECG signal processing logic unit is for amplifying and filtering noise reduction process to the ECG signal of acquisition.
Atrial fibrillation monitoring system of the invention is horizontal by the heart rate variability that continuous collecting analyzes PPG signal segment, is based on the heart The rate Deflection level judgement PPG signal segment whether there is atrial fibrillation;The temporal regularity round the clock of atrial fibrillation load is counted, Prompt user carries out ECG detection within the high atrial fibrillation load period, to improve the timeliness of atrial fibrillation ECG waveform capture, enables users to It is enough to obtain immunotherapy targeted autoantibody as early as possible, avoid the state of an illness from further developing.
According to the example of the disclosure, with reference to the composition schematic diagram of PPG heart rate variability evaluation module shown in Fig. 4, PPG heart rate Variance estimation module 204/304 is configured to include: PPG interphase extraction unit 4042, heartbeat interval variation value computing unit 4044 and atrial fibrillation score determination unit 4046.
Wherein, PPG interphase extraction unit 4042 is configured as between obtaining PPG heartbeat from extraction in PPG heartbeat signal segment Phase sequence.For example, inter-beat intervals sequence INT (n), n=1,2 are obtained by extracting the pulse crest interphase in PPG signal segment, 3 ... ....In order to obtain accurate atrial fibrillation judging result, the length of PPG heartbeat signal segment should generally include at least 30 companies Continuous heartbeat interval.
Heartbeat interval variation value computing unit 4044, is configured as based on inter-beat intervals sequence INT (n), calculates between heartbeat The variation value of phase.Wherein heartbeat interval variation value calculation formula are as follows:
DINT (n)=ABS (INT (n)/(INT (n)+INT (n-1)+INT (n-2)) -1/3) (formula 1)
Wherein, as n=1 or 2, dINT (n)=0 is taken.
Atrial fibrillation score determination unit 4046 is configured as searching dINT according to a preset variation value-score mapping table (n) the atrial fibrillation score value w (n) (n=1,2,3 ...) of (n=1,2,3 ...) correspondence mappings, by each w (n) (n=1,2,3 ...) It is cumulative, obtain heartbeat interval variation value sequence dINT (n) (n=1,2,3 ...) resulting accumulative atrial fibrillation score Sw
Further, due to the value for the dINT being calculated according to formula 1 may have unlimited kind as a result, described in order to simplify Variation value-score mapping table, preferably, the variation value is divided into several segments, every section of variation value is set each other off with an atrial fibrillation score value It penetrates.According to the exemplary statistic op- timization of the disclosure, the variation value is divided into 9 sections.
Since in most cases, heart beat rhythm is regular, therefore heart beat interval is similar, it may thus be appreciated that normally In the case of the value of dINT be located near 0 value, it is further known that, the corresponding atrial fibrillation score value of dINT close to 0 value should be smaller.According to warp Test statistics, the value of dINT relevant to atrial fibrillation concentrate on section [0.012,0.18), thus section [0.012,0.18) in The corresponding atrial fibrillation score of dINT is larger;And section [0,0.012) and [0.18,0.23) dINT mainly due to unrelated with atrial fibrillation Disturbing factor generate, therefore section [0,0.012) and [0.18,0.23) in the corresponding atrial fibrillation score of dINT it is smaller or It is negative.Exemplary, the preset variation value-score mapping table is as shown in table 1.
Table 1
Interphase variation value dINT Atrial fibrillation score value w
[0,0.012) -19.01
[0.012,0.045) 8.63
[0.045,0.07) 12.37
[0.07,0.11) 15.26
[0.11,0.13) 14.45
[0.13,0.16) 19.78
[0.16,0.18) 6.23
[0.18,0.2) -16.42
[0.2,0.23) -10.36
According to the example of the disclosure, the accumulative atrial fibrillation score SwIt is configured as the index of heart rate variability level, it is described Atrial fibrillation judgment module 210/310 is configured as the accumulative atrial fibrillation score SwCompared with a default score threshold δ, work as Sw≥δ When, judge that there are atrial fibrillations for the PPG heartbeat signal segment, works as SwWhen < δ, judging the PPG heartbeat signal segment, there is no rooms It quivers.Wherein exemplary, the threshold value δ of setting is equal with heartbeat interphase number.
It is the inter-beat intervals sequence INT1 (n) of extraction, corresponding in one section of exemplary 39 seconds PPG heartbeat signal segment Heartbeat interval makes a variation value sequence dINT1 (n) and atrial fibrillation score value w1 (n) corresponding to table 1 is as shown in table 2, wherein presets Score threshold δ=60 point, according to table 2 calculate dINT1 (n) (n=1~60) accumulative atrial fibrillation score S1wIt is 243.72, S1wGreatly In δ, therefore judge that this section of PPG heartbeat signal segment includes atrial fibrillation.
Table 2
In another section of exemplary 71 seconds PPG heartbeat signal segment, the inter-beat intervals sequence INT2 (n) of extraction, correspond to Heartbeat interval variation value sequence dINT2 (n) and atrial fibrillation score value w2 (n) corresponding to table 1 it is as shown in table 3, wherein set in advance Score threshold δ=60 point set calculate the accumulative atrial fibrillation score S2 of dINT2 (n) (n=1~60) according to table 3wIt is -238.27, S2wLess than δ, therefore judge that this section of PPG heartbeat signal segment does not include atrial fibrillation.
Table 3
Atrial fibrillation monitoring system of the invention, by extracting the PPG interphase being tested in the PPG heartbeat signal segment of individual in terms of The variation value of PPG interphase is calculated, different atrial fibrillation score values is distributed for different variation values, in the PPG heartbeat signal segment Each interphase variation is worth corresponding atrial fibrillation score value and carries out accumulation calculating, when accumulative atrial fibrillation score is greater than preset score threshold When, judge that the PPG heartbeat signal segment includes atrial fibrillation.The atrial fibrillation deterministic process of the atrial fibrillation monitoring system is simple, imitates Rate is high, PPG heartbeat signal segment appropriate for length judging nicety rate with higher.
Three embodiments presented below are described further above-mentioned atrial fibrillation monitoring system, since three embodiments are in many Aspect has similitude, and similar modules/devices/equipment is indicated by similar label.
In an exemplary atrial fibrillation monitoring system, with reference to Fig. 5, atrial fibrillation monitoring system 500 includes 510 (example of wearable device Such as wrist wearable device refers to portion's wearable device, neck wearable device, ear's wearable device), with it is described wearable The user equipment such as intelligent mobile terminal 520 (such as smart phone, tablet computer etc.) and data clothes of equipment wireless communication Business device 530.Wherein, the wearable device 510 can pass through bluetooth, RF, audio or NFC etc. with the intelligent mobile terminal 520 Near radio mode communicates.
The wearable device 510 is configured to include memory, processor, communication unit, display unit, human-computer interaction Module, PPG signal acquisition process module 202/302, motor message acquisition processing module 216/316, PPG heart rate variability assess mould Block 204/304, atrial fibrillation judgment module 206/306 and ECG signal acquisition processing module 214/314;The intelligent mobile terminal 520 are configured to include memory, processor, human-computer interaction module, display unit, communication unit and the wearable device Corresponding wearing APP, atrial fibrillation logging modle 208/308, atrial fibrillation statistical module 210/310 and cue module 212/312.
Cue module 212/312 directly can issue prompting message by the intelligent mobile terminal 520 and user is prompted to carry out ECG detection, can also be communicated by intelligent mobile terminal 520 with wearable device 510, issued prompt by wearable device 510 and disappeared Breath prompt user carries out ECG detection.Specific prompting mode can be prompt or sound and text of the vibration in conjunction with text The prompt of this combination.
The ECG signal of the monitored individual of 214/314 acquisition process of ECG signal acquisition processing module can be by wearable device 510 are sent to the intelligent mobile terminal 520, then are uploaded to data server 530 further by the intelligent mobile terminal 520 Processing and analysis.
In another exemplary atrial fibrillation monitoring system, with reference to Fig. 6, atrial fibrillation monitoring system 600 include wearable device 610 with And the data server 630 with wearable device wireless communication.Wherein, the wearable device 610 takes with the data Business device 630 can pass through the wireless communication modes such as 3G/4G/LTE, GPRS, wifi.
The wearable device 610 is configured to include memory, processor, communication unit, display unit, human-computer interaction Module, PPG signal acquisition process module 202/302, motor message acquisition processing module 216/316, PPG heart rate variability assess mould Block 204/304, atrial fibrillation judgment module 206/306, atrial fibrillation logging modle 208/308, atrial fibrillation statistical module 210/310, prompt mould Block 212/312 and ECG signal acquisition processing module 214/314.Specific prompting mode can be vibration in conjunction with text The prompt of prompt or sound in conjunction with text.
The ECG signal of the monitored individual of 214/314 acquisition process of ECG signal acquisition processing module can be by wearable device The data server 630 is sent to be further processed and analyze.Optionally, atrial fibrillation monitoring system 600 can also include and institute State the intelligent mobile terminal 620 of the wireless communication of wearable device 610, the wearable device 610 and the intelligent mobile terminal 620 can be communicated by the near radios mode such as bluetooth, RF, audio or NFC.ECG signal acquisition processing module 214/314 acquires The ECG signal of the monitored individual of processing can be sent to intelligent mobile terminal 620 by wearable device, then by intelligent mobile terminal 620, which are forwarded to data server 630, is further processed and analyzes.
In another exemplary atrial fibrillation monitoring system, with reference to Fig. 7, atrial fibrillation monitoring system 700 include wearable device 710 with And the data server 730 with wearable device wireless communication;Wherein, the wearable device 710 takes with the data Business device 730 can pass through the wireless communication modes such as 3G/4G/LTE, GPRS, wifi.
The wearable device 710 is configured to include memory, processor, communication unit, display unit, human-computer interaction Module, PPG signal acquisition process module 202/302, motor message acquisition processing module 216/316, PPG heart rate variability assess mould Block 204/304, atrial fibrillation judgment module 206/306 and ECG signal acquisition processing module 214/314.The data server quilt Be configured to include memory, processor, communication unit, atrial fibrillation logging modle 208/308, atrial fibrillation statistical module 210/310 and Cue module 212/312.
When atrial fibrillation judgment module 206/306 determines to occur atrial fibrillation, atrial fibrillation event data is sent to by wearable device 710 The data server 730, is stored by atrial fibrillation logging modle 208/308.The data server 730 passes through cue module 212/ 312, which send ECG to the wearable device 710, detects prompting message, and wearable device 710 is by ECG signal acquisition processing module The ECG signal of the monitored individual of 214/314 acquisition process is sent to the data server 730 and is further processed and analyzes.
Optionally, atrial fibrillation monitoring system 700 can also include the intelligent mobile with the wearable device 710 wireless communication Terminal 720, the wearable device 710 can be by bluetooth, RF, audio or NFC etc. closely with the intelligent mobile terminal 720 Wireless communication mode.When atrial fibrillation judgment module 206/306 determines to occur atrial fibrillation, wearable device 710 is by atrial fibrillation event data It is sent to the intelligent mobile terminal 720, intelligent mobile terminal 720 is forwarded to data server 730, by atrial fibrillation logging modle 208/308 storage.It will be appreciated by those skilled in the art that, data server 730 can also be to the intelligent mobile terminal 720 It sends ECG and detects prompting message, user is prompted to carry out ECG detection in the atrial fibrillation load biggish period.Wearable device 710 will The ECG signal of the monitored individual of 214/314 acquisition process of ECG signal acquisition processing module is sent to intelligent mobile terminal 720, Data server 730 is forwarded to by intelligent mobile terminal 720 to be further processed and analyze.
Configuration enlightenment based on above-mentioned three kinds specific systems, it will be appreciated by those skilled in the art that, it can also be by institute State PPG signal acquisition process module 202/302, motor message acquisition processing module 216/316 and ECG signal acquisition process mould The configuration of block 214/314 at wearable device end, by PPG heart rate variability evaluation module 204/304, atrial fibrillation judgment module 206/306, Atrial fibrillation logging modle 208/308, atrial fibrillation statistical module 210/310 and the configuration of cue module 212/312 are in server end;Or Person, will be by the PPG signal acquisition process module 202/302, motor message acquisition processing module 216/316 and ECG signal Acquisition processing module 214/314 configures at wearable device end, and PPG heart rate variability evaluation module 204/304, atrial fibrillation are judged mould Block 206/306, atrial fibrillation logging modle 208/308, atrial fibrillation statistical module 210/310 and the configuration of cue module 212/312 are in intelligence A variety of other specific embodiments such as energy mobile terminal, details are not described herein.
Alleged processor can be central processing unit (Central Processing Unit, CPU), can also be it His general processor, digital signal processor (Digital Signal Processor, DSP), specific integrated circuit (Application Specific Integrated Circuit, ASIC), ready-made programmable gate array (Field- Programmable Gate Array, FPGA) either other programmable logic device, discrete gate or transistor logic, Discrete hardware components etc..General processor can be microprocessor or the processor is also possible to any conventional processor Deng.
The memory can be used for storing the module and/or unit, and the processor is stored in by operation or execution The corresponding computer program of module/unit in the memory, and the data being stored in memory are called, described in realization The various functions of device.In addition, memory may include high-speed random access memory, it can also include non-volatile memories Device, such as hard disk, memory, plug-in type hard disk, intelligent memory card (Smart Media Card, SMC), secure digital (Secure Digital, SD) card, flash card (Flash Card), at least one disk memory, flush memory device or other volatibility are solid State memory device.
To sum up, the atrial fibrillation monitoring system that the disclosure proposes can be become by continuing to monitor the heart rate of PPG heartbeat signal segment The different monitored individual of horizontal judgement whether there is atrial fibrillation, pass through the atrial fibrillation of 0 point~24 points of statistics time range different periods round the clock Load level prompts user to carry out ECG detection within the high atrial fibrillation negative period, to improve the timeliness of capture atrial fibrillation ECG waveform.This Disclosed atrial fibrillation monitoring system module simple structure is applicable to include wearable PPG detection device or wearable PPG/ECG inspection In three end application systems of measurement equipment, intelligent mobile terminal and data server.
It will appreciated by the skilled person that realizing that the function of all or part of module of above-described embodiment can lead to Hardware is crossed to complete, relevant hardware can also be instructed to complete by program.
Those skilled in the art will readily occur to other embodiment party of the application after considering specification and practicing the disclosure Case.This application is intended to cover any variations, uses, or adaptations of the application, these modifications, purposes or adaptability Variation follows the general principle of the application and including the undocumented common knowledge or usual skill in the art of the application Art means.
The foregoing is merely the preferred embodiments of the application, not to limit the application, it is all in spirit herein and Any modification, equivalent replacement or improvement for being made within principle etc., should be included within the scope of protection of this application.

Claims (10)

1. a kind of atrial fibrillation monitoring system characterized by comprising
PPG signal acquisition process module is monitored the PPG heartbeat signal of individual for continuous collecting to provide PPG heartbeat signal Segment;
PPG heart rate variability evaluation module, the heart rate variability for assessing the PPG heartbeat signal segment are horizontal;
Atrial fibrillation judgment module, for judging the PPG heartbeat signal segment with the presence or absence of atrial fibrillation based on the heart rate variability level;
Atrial fibrillation logging modle records atrial fibrillation event data for being judged there are when atrial fibrillation when the PPG heartbeat signal segment, Wherein, the atrial fibrillation event data includes the acquisition time with the PPG heartbeat signal segment of the atrial fibrillation event correlation;
Atrial fibrillation statistical module, for being based on several atrial fibrillation event datas, statistics obtains the atrial fibrillation load of different periods round the clock; And
Cue module, for prompting the monitored individual to carry out ECG detection in atrial fibrillation load maximum one or more periods.
2. system according to claim 1, which is characterized in that the index of the atrial fibrillation load includes the atrial fibrillation event number According to quantity.
3. system according to claim 1, which is characterized in that several atrial fibrillation event datas include several days, The atrial fibrillation event data in several weeks or several months.
4. described in any item systems according to claim 1~3, which is characterized in that further include:
ECG signal acquisition processing module, device needed for being used to provide the described ECG detection.
5. system according to claim 4, which is characterized in that further include:
Motor message acquisition processing module, for dress needed for providing the influence for reducing the accuracy that motion artifacts judge atrial fibrillation It sets.
6. system according to claim 5, which is characterized in that the PPG heart rate variability evaluation module includes:
PPG interphase extraction unit obtains PPG inter-beat intervals sequence for extracting from the PPG heartbeat signal segment;
Heartbeat interval variation value computing unit, for heartbeat interval variation value to be calculated based on the PPG inter-beat intervals sequence Sequence;And
Atrial fibrillation score determination unit, for calculating the heartbeat interval variation value according to a preset variation value-score mapping table The resulting accumulative atrial fibrillation score of sequence;
Wherein, the accumulative atrial fibrillation score is configured as the index of the heart rate variability level, the atrial fibrillation judgment module It is configured as by the accumulative atrial fibrillation score compared with a default score threshold, judges that the PPG heartbeat is believed according to comparison result Number segment whether there is atrial fibrillation.
7. system according to claim 6, which is characterized in that the variation value-score mapping table is configured to include Several atrial fibrillation score values and several interphase variation value segments mapped with several atrial fibrillation score values.
8. system according to claim 7, which is characterized in that the heartbeat interval variation value computing unit is configured as root According to formula dINT (n)=ABS, (INT (n)/((INT (n)+INT (n-1)+INT (n-2)) -1/3) calculates the variation of each interphase Value, wherein INT (n) indicates the time interval of n-th of interphase, and INT (n-1) and INT (n-2) are indicated close to before n-th of interphase The time interval of two interphases, n >=3.
9. system according to claim 8, which is characterized in that the variation value-score mapping table is configured to include 9 Interphase variation value segment, the interphase variation value [0,0.012) segment and [0.18,0.23) segment correspondence mappings Atrial fibrillation score value is negative, [0.012,0.18) the atrial fibrillation score values of segment correspondence mappings is positive.
10. a kind of wearable device, which is characterized in that including atrial fibrillation monitoring system according to any one of claims 1 to 9.
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Application publication date: 20190702