CN109900646A - Optical fiber type bimodal imaging system and optical fiber type bimodal imaging method - Google Patents
Optical fiber type bimodal imaging system and optical fiber type bimodal imaging method Download PDFInfo
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Abstract
A kind of optical fiber type bimodal imaging system and optical fiber type bimodal imaging method, the optical fiber type bimodal imaging system include: the optical fiber laser for issuing laser pulse；It is connect with optical fiber laser, is used for transmission the optical fiber transmission module of laser pulse；For laser pulse to be split to obtain the first beam splitter of terahertz laser pulse and Fluorescence laser pulse；For being split and transmitting to terahertz laser pulse to obtain THz wave, and THz wave and sample are had an effect to obtain the Terahertz module of terahertz signal；For receiving Fluorescence laser pulse, and Fluorescence laser pulse concentration is generated to the fluorescent moieties of fluorescence signal in sample；And connect with Terahertz module and fluorescent moieties, for being coupled to terahertz signal and fluorescence signal to obtain the imaging device of the multidimensional information of sample；Two kinds of imaging patterns of Terahertz and fluorescence are carried out close-coupled by optical fiber type bimodal imaging system, can obtain multidimensional high-resolution sample message simultaneously.
Description
Technical field
The invention belongs to THz wave technical field of imaging more particularly to a kind of optical fiber type bimodal imaging system and optical fiber
Formula bimodal imaging method.
Background technique
THz wave is a kind of electromagnetic wave, and since THz wave has specific frequency, many non-polar materials are for too
The degree of absorption of Hertz wave is smaller, by THz wave can detect material interior spatial structure and material composition at
Point, and the structure of material will not be damaged during being detected to material；Therefore THz wave is extensive
It applies in each industrial technical fields such as the analyses and identification of material on ground；THz wave interacts with various physical materials
Afterwards, the physical message of a variety of materials is carried by the THz wave that material gives off, and then is achieved that according to THz wave
The slight change of physical material is accurately monitored；The THz wave can be used for article identification, materialogy, safety inspection
Etc. every field, it is greatly convenient to bring to people's lives, and THz wave imaging technique also becomes current technology people
The focus on research direction of member.
On the other hand, fluorescence imaging is also a kind of wider imaging technique of application, have be imaged it is low in cost, for target
The contour detecting of the object advantage relatively clear with imaging；However article is imaged, in identification process in traditional technology, nothing
By being THz wave imaging or fluorescence imaging etc., optical transport mode all uses free-space optical transmission, and this optical transport is trembled
The stability that dynamic and optical mirror slip deviation will lead to system is poor, and photoimaging systems are relatively too fat to move, and integration degree is lower,
The integration degree of circuit system is lower, is unfavorable for practical application；In addition, traditional THz wave imaging system and fluorescence imaging
System is autonomous system, can not meet large scale and high-resolution demand in actual application simultaneously, and obtain
Sample message is single, and then significantly limits the development and application of THz wave imaging technique and Imaging-PAM, and
It is lower for the structure detection precision and efficiency of material.
Summary of the invention
In view of this, the embodiment of the invention provides a kind of optical fiber type bimodal imaging systems and optical fiber type bimodal to be imaged
Method, it is intended to when solving traditional technical solution for object progress THz wave imaging or fluorescence imaging, photoimaging systems
It is relatively too fat to move, stability is poor, integration degree is lower, detection accuracy and imaging resolution are lower and can not obtain simultaneously more
The problem of tieing up information etc..
The first aspect of the embodiment of the present invention provides a kind of optical fiber type bimodal imaging system, comprising:
For issuing the optical fiber laser of laser pulse；
It is connect with the optical fiber laser, is used for transmission the optical fiber transmission module of the laser pulse；
Connect with the optical fiber transmission module, for by the laser pulse be split to obtain terahertz laser pulse and
First beam splitter of Fluorescence laser pulse；
It is connect with first beam splitter, for the terahertz laser pulse to be split and transmitted to obtain terahertz
Hereby wave, and the THz wave and sample are had an effect to obtain the Terahertz module of terahertz signal；
It connect with first beam splitter, gathers for receiving the Fluorescence laser pulse, and by the Fluorescence laser pulse
Coke generates the fluorescent moieties of fluorescence signal in the sample；And
It is connect with the Terahertz module and the fluorescent moieties, for the terahertz signal and the fluorescence signal
It is coupled to obtain the imaging device of the multidimensional information of the sample.
In one of them embodiment, the optical fiber transmission module include: it is a plurality of it is sequentially connected, be used for transmission it is described
First transmission fiber of laser pulse；
The Terahertz module include: it is a plurality of sequentially connected, be used for transmission the terahertz laser pulse second pass
Lose fibre；
The fluorescent moieties include: it is a plurality of sequentially connected, be used for transmission the Fluorescence laser pulse third transmission light
It is fine.
In one of them embodiment, the optical fiber transmission module further include:
At least one, be connected between first transmission fiber of adjacent two, for the laser pulse carry out
First fiber interface module of compatible transmission and fixed first transmission fiber；
At least one, be connected between first transmission fiber of adjacent two, for the laser pulse of decaying
First optical attenuator of optical power；And
At least one, be connected between first transmission fiber of adjacent two, for adjusting the laser pulse
First optical fiber polarization controller of polarization state；
The Terahertz module further include:
At least one, be connected between second transmission fiber of adjacent two, for the thz laser arteries and veins
Rush in the second fiber interface module of row compatible transmission and fixed second transmission fiber；
At least one, be connected between second transmission fiber of adjacent two, for adjusting the thz laser
Second optical attenuator of the optical power of pulse；And
At least one, be connected between second transmission fiber of adjacent two, for adjusting the thz laser
Second optical fiber polarization controller of the polarization state of pulse；
The fluorescent moieties further include:
At least one, be connected between the third transmission fiber of adjacent two, for the Fluorescence laser pulse
Carry out the third fiber interface module of compatible transmission and the fixed third transmission fiber.
In one of them embodiment, first fiber interface module include: sequentially connected first fibre-optical splice,
First optical fiber matches casing and the second fibre-optical splice；Wherein first fibre-optical splice connects first transmission fiber, described
Second fibre-optical splice connects another first transmission fiber；
The first optical fiber matching casing is for fixing first fibre-optical splice and second fibre-optical splice；
Second fiber interface module include: sequentially connected third fibre-optical splice, the second optical fiber matching casing and
4th fibre-optical splice；Wherein the third fibre-optical splice connects second transmission fiber, and the 4th fibre-optical splice meets another institute
State the second transmission fiber；
The second optical fiber matching casing is for fixing the third fibre-optical splice and the 4th fibre-optical splice；
The third fiber interface module include: sequentially connected 5th fibre-optical splice, third optical fiber matching casing and
Six fibers connector, wherein the 5th fibre-optical splice connects a third transmission fiber, the six fibers connector connects another
The third transmission fiber；
The third optical fiber matching casing is for fixing the 5th fibre-optical splice and the six fibers connector.
In one of them embodiment, the Terahertz module includes:
It is connected between two second transmission fibers, is pumped for being split to the terahertz laser pulse
Second beam splitter of Pu light and detection light；
It is connected between two second transmission fibers, for receiving the pump light, and in the drive of the pump light
The terahertz emission module of the THz wave is given off under dynamic；
Be connected between two second transmission fibers, be used for transmission the detection light, and receive act on it is described
The terahertz detection module of THz wave after sample；And
It is connect by the first cable with the terahertz detection module, and is connected by the second cable and the imaging device
It connects, generates institute for acquiring the THz wave after acting on the sample, and according to the THz wave after the sample is acted on
State the lock-in amplifier module of terahertz signal.
In one of them embodiment, the lock-in amplifier module includes:
It is connect by first cable with the terahertz detection module, is acted on after the sample too for acquiring
Hertz wave generates current signal under the driving for acting on the THz wave after the sample, and puts to the current signal
Big preamplifier；
It is connect with the preamplifier, the lock-in amplifier of the amplitude for detecting the current signal；And
It connect with the lock-in amplifier, and is connect by second cable with the imaging device, be used for basis
The amplitude of the current signal obtains the adc data capture card of the terahertz signal.
In one of them embodiment, the terahertz emission module includes:
A plurality of sequentially connected second transmission fiber, second transmission fiber are used for transmission the pump light；
At least one, second fiber interface module being connected between second transmission fiber of adjacent two,
Second fiber interface module is used to carry out the pump light compatible transmission and fixed second transmission fiber；
At least one, be connected between second transmission fiber of adjacent two, for matching and eliminating described
First dispersion compensating fiber of the dispersion of two transmission fibers；
It is connect with the lock-in amplifier module, the modulating frequency for being exported according to the lock-in amplifier module generates
The bias voltage module of bias voltage；And
It connect, is connect by third cable with the bias voltage module, and and sample with second transmission fiber
Storehouse is oppositely arranged, and for receiving the pump light, and gives off under the driving of the bias voltage light of the THz wave
Conductance radiating antenna；Wherein, the sample bin is for accommodating the sample.
In one of them embodiment, the terahertz detection module includes:
A plurality of sequentially connected second transmission fiber, second transmission fiber are used for transmission the detection light；
At least one, second fiber interface module being connected between second transmission fiber of adjacent two,
Second fiber interface module is used to carry out the detection light compatible transmission and fixed second transmission fiber；
At least one, be connected between second transmission fiber of adjacent two, for matching and eliminating described
Second dispersion compensating fiber of the dispersion of two transmission fibers；
Be connected between second transmission fiber of adjacent two, for adjust the pump light and the detection light it
Between relative delay delay line device；And
It connect with second transmission fiber, and is oppositely arranged with sample bin, for being made according to the detection light-receiving
Photoconductive exploring antenna for the THz wave after the sample；Wherein, the sample bin is for accommodating the sample.
In one of them embodiment, the fluorescent moieties further include:
It is connected between two third transmission fibers, for matching and eliminating the dispersion of the third transmission fiber
Third dispersion compensating fiber；
It is connect with the third transmission fiber, the optical-fiber bundling for the Fluorescence laser pulse to be synthesized and transmitted
Device；Wherein, the optical-fiber bundling device is also used to collect what the sample issued under the excitation of the Fluorescence laser pulse
The fluorescence signal；
The optical-fiber bundling device is connected by doubly clad optical fiber, for transmitting after collimating to the Fluorescence laser pulse
Optical fiber collimator；
It connect with the optical fiber collimator, and is oppositely arranged with the sample bin, for the Fluorescence laser after collimating
The optical imaging objective being imaged in pulse concentration to the sample；Wherein the sample bin is for accommodating the sample；
It is connect with the optical-fiber bundling device, is used for transmission the multimode signal optical fiber of the fluorescence signal；
It is connect with the multimode signal optical fiber, the bandpass filter being filtered for the wavelength to the fluorescence signal；
And
It connect, is connect by the 4th cable with the imaging device, for acquiring wavelength through band with the bandpass filter
The photomultiplier tube of the filtered fluorescence signal of pass filter.
The second aspect of the embodiment of the present invention provides a kind of optical fiber type bimodal imaging method, comprising:
It obtains and transmits laser pulse；
The laser pulse is split to obtain terahertz laser pulse and Fluorescence laser pulse；
The terahertz laser pulse is split and is transmitted to obtain THz wave, and by the THz wave and sample
Interaction occurs for product to generate terahertz signal；
The Fluorescence laser pulse is received, and the Fluorescence laser pulse concentration is believed in the sample with generating fluorescence
Number；And
The terahertz signal and the fluorescence signal are coupled to obtain the multidimensional information of the sample.
Laser pulse is split to obtain terahertz laser pulse and fluorescence by above-mentioned optical fiber type bimodal imaging system
Laser pulse；After being sampled, analyzed for sample by terahertz laser pulse and Fluorescence laser pulse respectively, sample is realized
The THz wave imaging of product and fluorescence imaging two ways Parallel, to form bimodal imaging system；Believed according to Terahertz
Number and fluorescence signal big dimensional analysis and various dimensions acquisition of information are carried out for the details of morphology of sample, can accurately obtain sample
Various dimensions information, the optical fiber type bimodal imaging system it is compact-sized, be applicable to the form in various types sample
In information access process, integration degree is higher, and operation is more stable, functional stronger.
Detailed description of the invention
It to describe the technical solutions in the embodiments of the present invention more clearly, below will be to embodiment or description of the prior art
Needed in attached drawing be briefly described, it should be apparent that, the accompanying drawings in the following description is only of the invention some
Embodiment for those of ordinary skill in the art without any creative labor, can also be according to these
Attached drawing obtains other attached drawings.
Fig. 1 is the structural schematic diagram for the optical fiber type bimodal imaging system that one embodiment of the invention provides；
Fig. 2 is another structural schematic diagram for the optical fiber type bimodal imaging system that one embodiment of the invention provides；
Fig. 3 is the structural schematic diagram for the first fiber interface module that one embodiment of the invention provides；
Fig. 4 is the structural schematic diagram for the second fiber interface module that one embodiment of the invention provides；
Fig. 5 is the structural schematic diagram for the third fiber interface module that one embodiment of the invention provides；
Fig. 6 is the structural schematic diagram for the Terahertz module that one embodiment of the invention provides；
Fig. 7 is the structural schematic diagram for the lock-in amplifier module that one embodiment of the invention provides；
Fig. 8 is the structural schematic diagram for the terahertz emission module that one embodiment of the invention provides；
Fig. 9 is the structural schematic diagram for the terahertz detection module that one embodiment of the invention provides；
Figure 10 is the structural schematic diagram for the fluorescent moieties that one embodiment of the invention provides；
Figure 11 is the implementation flow chart for the optical fiber type bimodal imaging method that one embodiment of the invention provides.
Specific embodiment
In order to make the objectives, technical solutions, and advantages of the present invention clearer, with reference to the accompanying drawings and embodiments, right
The present invention is further elaborated.It should be appreciated that the specific embodiments described herein are merely illustrative of the present invention, and
It is not used in the restriction present invention.
It should be noted that THz wave refers to frequency in 0.1~10 Terahertz (Tera Hertz, THz), wave-length coverage
Electromagnetic radiation between 0.03~3mm, wave band be located at microwave and it is infrared between.Relative to the electromagnetic wave of its all band, terahertz
Hereby wave has many peculiar properties, and the photon energy of one side THz wave is very low, about 1~10meV, will not be to biological group
It knits and generates harmful ionising radiation；Compared to visible light and infrared spectroscopy, penetration capacity is stronger, and not vulnerable to Rayleigh scattering
It influences, image contrast is higher, can be widely applied in biomedical imaging and diagnostic field；On the other hand, due to being permitted
The vibration of more large biological molecules and rotational frequency are at Terahertz frequency range, therefore big using the available biology of terahertz emission
The characteristic spectral line of molecule, to realize to molecular structure, performance and the detection and analysis of slight change.However, by system construction, spoke
Penetrate the limitation of the hardware such as source and detector, it is slower that current THz wave imaging system mostly has imaging acquisition speed, imaging
Resolution ratio is low, specific not strong etc. shortcoming, causes certain restrictions to the promotion and application of THz wave imaging.
At the same time, fluorescence imaging can also obtain the parameters such as structural information and the morphological image of interior of articles, according to
Jablonski energy level theory, the fluorescent molecule in ground state transit to excitation state under the action of exciting light, later to radiate jump
The mode moved returns to ground state and generates fluorescence.Imaging-PAM is the fluorescence letter generated to determinand in the case where exciting light action
Number technology for being collected and being imaged.Fluorescence imaging have it is extraordinary specificity and targeting, biomolecule Mechanism Study,
The fields such as drug targeting tracking, disease detection have very extensive application prospect.But as a kind of high-resolution imaging
Technology, the imaging depth and areas imaging of fluorescence imaging are smaller, and imaging time is unsuitable too long, phototoxicity and photobleaching etc. easily occur
Phenomenon limits the practical application of fluorescence imaging to a certain extent.
In current THz wave imaging system and fluoroscopic imaging systems, since traditional imaging system requires to carry out
Light freely convert and the transmission of light, this results in the stability of imaging system poor, and imaging system is too fat to move, integrated journey
It is unreasonable to spend larger, internal circuit structure space layout, is unfavorable for practical application.
By taking tumor imaging as an example, although THz wave imaging technique image contrast is high, to the size and shape of tumour
Shape boundary demarcation inaccuracy, lacks the resolution ratio of detection tectology；Though and fluorescence imaging resolution ratio with higher and spy
It is anisotropic, it is possible to provide the necessary details of form is but limited to scanning range, can not show whole profiles of tumour；Based on this problem,
The embodiment of the present invention provides a kind of completely new optical fiber type bimodal imaging system, under the THz wave imaging technique of high contrast
After showing the general outline of tumour, high-resolution imaging and precise positioning are carried out to tumor boundaries using Imaging-PAM,
Necessary morphological analysis details is provided, diagnosing tumor is carried out for doctor and surgical cut provides foundation.The system structure simultaneously
Compact stabilization, stability is high, is conducive to movement and application in actual scene.Therefore, the optical fiber type bimodal imaging system
Be expected to the research in disease mechanisms, detection, diagnosis, it is postoperative tracking and newtype drug exploitation and in terms of play a role,
It realizes the accurate detection and analysis for determinand internal structure, promotes the well-being of mankind.
Referring to Fig. 1, the structural schematic diagram of optical fiber type bimodal imaging system 10 provided in an embodiment of the present invention, in order to just
In explanation, only the parts related to this embodiment are shown, and details are as follows:
The optical fiber type bimodal imaging system 10 includes: optical fiber laser 101, optical fiber transmission module 102, the first beam splitting
Device 103, Terahertz module 104, fluorescent moieties 105 and imaging device 106.
Wherein, the optical fiber laser 101 is for issuing laser pulse.
Wherein, the laser pulse includes laser intelligence, to realize signal radiation function；Optionally, the optical-fiber laser
Device 101 is optical fiber femtosecond laser；Related technical personnel can according to the requirement adjustment of the precision of detection and imaging resolution or
Replace optical fiber laser 101 type and parameter, with ensured optical fiber type bimodal imaging system 10 signal transmission quality and
Effectiveness.
Optical fiber transmission module 102 is connect with optical fiber laser 101, is used for transmission laser pulse.
The optical fiber transmission module 102 has the function of that laser pulse delivery, the optical fiber transmission module 102 utilize itself
Fiber transmission performance, can avoid laser pulse transmission quality loss；And the optical fiber transmission module 102 can keep laser
The linear polarization of pulse remains unchanged, and improves the transmission signal-to-noise ratio of laser pulse.
First beam splitter 103 is connect with the optical fiber transmission module 102, for the laser pulse to be split to obtain
Terahertz laser pulse and Fluorescence laser pulse.It is understood that " terahertz laser pulse " means for finally generating too
The laser pulse of Hertz wave, " Fluorescence laser pulse " mean the laser pulse for finally generating fluorescence.
By the first beam splitter 103 energy beam splitting can be carried out to laser pulse, so that first beam splitter 103 output
Terahertz laser pulse and Fluorescence laser pulse have different signal form and signal energy, and then the optical fiber type bimodal
Imaging system 10 can realize the compatible transmission of THz wave and fluorescence two ways according to laser pulse.
Terahertz module 104 is connect with first beam splitter 103, for being split to the terahertz laser pulse
With transmission to obtain THz wave, and the THz wave and sample 20 are had an effect to obtain terahertz signal；When passing through
After Terahertz module 104 is split terahertz laser pulse, wherein it is a branch of for obtaining THz wave, and by described in too
Hertz wave acts on sample 20 to generate terahertz signal；For detecting terahertz signal, i.e., another beam Terahertz swashs another beam
Light pulse carries out the information of acquisition sample 20 after data processing in conjunction with terahertz signal in corresponding computer.
Wherein, the terahertz laser pulse is in the effectiveness with higher of Terahertz module 104, due to terahertz
Hereby wave itself has lower energy, therefore hardly damages to sample 20.When sample 20 receives THz wave, with
The terahertz signal that sample 20 gives off after interacting contains the shape information of the various aspects of sample 20, according to terahertz
Hereby the variation of the self-operating parameter of signal obtains the structural information of sample 20, realizes and function is imaged for the THz wave of sample
Energy；Terahertz detection is carried out by the structure for sample 20, has advantageously reduced the detection of the shape information for sample 20
Error.
Fluorescent moieties 105 are connect with first beam splitter 103, for receiving the Fluorescence laser pulse, and will be described
Fluorescence laser pulse concentration is in the sample 20 to generate fluorescence signal.
The Fluorescence laser pulse has specific power, and is able to maintain Fluorescence laser arteries and veins by fluorescent moieties 105
The energy and efficiency of punching, the Fluorescence laser pulse after collimation focusing have higher energy and efficiency of transmission, it can be achieved that sample
20 efficient fluorescence excitations, and can avoid causing fluorescent moieties 105 internal electron member device occur due to the reflection of laser pulse
The damage of part.By carrying out efficient fluorescence excitation to sample 20 and signal acquisition can reach optimal test effect.
Imaging device 106 is connect with the Terahertz module 104 and the fluorescent moieties 105, for the Terahertz
Signal and the fluorescence signal are coupled to obtain the multidimensional information of the sample.
Optionally, the multidimensional information includes the structure of sample 20 and at being grouped as；Sample can be obtained by multidimensional information
20 clearly image and complete form provide scientific reference for the necessary morphological analysis of sample 20.
Optionally, imaging device 106 is industrial personal computer or personal computer；Illustratively, imaging device 106 includes system
Control module, the functions such as system control module system control, data sampling and processing and analysis, imaging device 106 have complexity
The function of signal processing and information analysis；When Terahertz module 104 exports terahertz signal to imaging device 106, fluorescence mould
When block 105 exports fluorescence signal to imaging device 106, the imaging device 106 for terahertz signal and fluorescence signal into
After row data analysis and process, the clear image information and internal composed structure information of sample 20 are obtained, realizes sample 20 too
Combination between Hertz wave imaging and fluorescence imaging, technical staff can intuitively obtain corresponding image from imaging device 106
And marginal information.
The structural representation of optical fiber type bimodal imaging system 10, the optical fiber type bimodal imaging system 10 are shown in Fig. 1
Terahertz signal and fluorescence signal are subjected to compatible transmission, THz wave imaging and fluorescence imaging can realize close-coupled, with complete
Orientation, the form and space structure for accurately obtaining sample 20 have higher resolution ratio and identification essence for sample 20
Degree；And the structure connection relationship of the internal circuit configuration module of the optical fiber type bimodal imaging system 10 more simplifies, too
Hertz signal and fluorescence signal transmit between circuit module has higher transmission precision and efficiency of transmission, compact-sized, collection
At changing, degree is higher, carries out high-precision and comprehensive analysis for the shape information of the various aspects of sample 20；And then the optical fiber
Formula bimodal imaging system 10 can be applied to the research of disease mechanisms, detection, diagnosis, postoperative tracking and newtype drug exploitation and
In the functional areas such as screening, entire society is benefited, there is high application value；Efficiently solve Terahertz in traditional technology
Wave imaging or fluorescence imaging be in referring now to object information content obtain it is single, for object internal information detection accuracy and
Sensitivity is all relatively low, and the occupied space volume of traditional imaging system is larger, the limited problem of application range.
As an alternative embodiment, Fig. 2 shows optical fiber type bimodal imaging systems 10 provided in this embodiment
Another structural representation, compared to the structure of optical fiber type bimodal imaging system 10 in Fig. 1, Fig. 2 shows optical fiber type it is double
In modality imaging system 10, the optical fiber transmission module 102 include: it is a plurality of it is sequentially connected, be used for transmission the laser pulse
The first transmission fiber 1021；Wherein, higher optical fiber efficiency of transmission and precision can be kept by the first transmission fiber 1021, and
And the laser pulse efficiency of transmission with higher and transmission precision in the first transmission fiber 1021；It is carried out in laser pulse
The process of optical fiber transmission, and optical fiber transmission mode anti-interference with higher and anti-shielding, considerably reduce
The debugging function of jitter phenomenon and free-space optical transmission of the laser pulse in transmission process, the optical fiber type bimodal imaging
System 10 is more stable, and the operation is more convenient.
The Terahertz module 104 include: it is a plurality of sequentially connected, be used for transmission the second of the terahertz laser pulse
Transmission fiber 1041；Second transmission fiber 1041 can retain the structural information inside terahertz laser pulse, and Terahertz swashs
There is higher energy to concentrate performance for light pulse, to obtain the details of morphology of sample 20 being more clear.
The fluorescent moieties 105 include: it is a plurality of sequentially connected, be used for transmission the Fluorescence laser pulse third transmission
Optical fiber 1051；Fluorescence laser pulse is exported to sample 20, third transmission fiber 1051 by a plurality of third transmission fiber 1051
Make the Fluorescence laser pulse that there is higher transmission precision and efficiency of transmission, the fluorescence realized according to the Fluorescence laser pulse
Imaging function has higher resolution ratio and structure detection sensitivity.
As an alternative embodiment, referring to figure 2., the optical fiber transmission module 102 further include: at least one
One fiber interface module 1022, at least one first optical attenuator 1023 and at least one first optical fiber polarization controller
1024。
Wherein, first fiber interface module 1022 be connected to first transmission fiber 1021 of adjacent two it
Between, for carrying out compatible transmission and fixed first transmission fiber 1022 to the laser pulse；Wherein, pass through the first light
Fine interface module 1022 can make to realize physical connection between two adjacent the first transmission fibers 1021, and laser pulse is in the first light
Fine interface module 1022 realizes lossless quick transmission, includes more by the laser pulse that the first fiber interface module 1022 exports
High frequency integrity and polarization characteristic.
First optical attenuator 1023 is connected between first transmission fiber 1021 of adjacent two, for decaying
State the optical power of laser pulse；So that decaying after the completely compatible optical fiber of laser pulse on transmission frequency, retain the laser
Intensity of the pulse in transmission process.
First optical fiber polarization controller 1024 is connected between first transmission fiber 1021 of adjacent two, for adjusting
Save the polarization state of the laser pulse；There is the polarization characteristic to match with optical fiber by the laser pulse after adjusting, improve
For the image sensitivity and imaging rate of sample 20.
Optionally, first optical fiber polarization controller 1024 is miniature double paddle Polarization Controllers, and then optical fiber transmits mould
Block has less spatial volume, and the scope of application is wider.
Optionally, it adopts and is screwed between the first optical attenuator 1023 and the first transmission fiber 1021；First optical fiber
It adopts and is screwed between Polarization Controller 1024 and the first transmission fiber 1021；The optical fiber transmission module 102 has more steady
Solid space structure, the layout between each component is more compact, and the efficiency of transmission of laser pulse is higher, the detection of sample
It can be more preferably.
In the present embodiment, matching in conjunction with the first optical attenuator 1023 and the first optical fiber polarization controller 1024 makes
With the transmission performance and efficiency of transmission of laser pulse being changed, and then adjust the beam splitting ratio of the first beam splitter 103, so that too
Energy ratio between hertz laser pulse and Fluorescence laser pulse can realize automatic adjusument；Due to 104 He of Terahertz module
Required optical power is not identical between fluorescent moieties 105, and the function of the laser pulse issued by optical fiber laser 101
Rate very likely has exceeded optical power required for 105 the two of Terahertz module 104 and fluorescent moieties；Therefore the present embodiment is logical
It crosses the first optical attenuator 1023 and the first optical fiber polarization controller 1024 carrys out the laser of the access of the first beam splitter of flexible modulation 103
The optical power and beam splitting ratio of pulse, by the light after 103 beam splitting of the first beam splitter respectively in Terahertz module 104 and fluorescence
Module 105 carries out compatible transmission, protects the physical security of each electronic component in module, the optical fiber type bimodal imaging
System 10 realizes optimal sample image checking effect, first beam splitter 103 by THz wave and Fluorescence laser pulse
Light after beam splitting has higher Modulatory character.
The Terahertz module 104 further include: at least one second fiber interface module 1042, at least one second optics
Attenuator 1043 and at least one second optical fiber polarization controller 1044.
Wherein, the second fiber interface module 1042 is connected between second transmission fiber 1041 of adjacent two, is used
In to terahertz laser pulse progress compatible transmission and fixed second transmission fiber 1041；It is connect by the second optical fiber
Mouth mold block 1042 can make the internal circuit configuration of Terahertz module 104 more firm so that THz wave imaging it is more accurate and
Reliably；And terahertz laser pulse is avoided in transmission process by noise jamming, remains the terahertz laser pulse
Original frequency information and energy integrality.
Second optical attenuator 1043 is connected between second transmission fiber 1041 of adjacent two, for adjusting
State the optical power of terahertz laser pulse；Optionally, the second optical attenuator 1043 can reduce the light of terahertz laser pulse
Power avoids so that the terahertz laser pulse after optical power reduces keeps higher efficiency of transmission in Terahertz module 104
Electronic component inside Terahertz module 104 suffers damage；The present embodiment reaches sample 20 by terahertz laser pulse
To optimal structured testing effect.
Second optical fiber polarization controller 1044 is connected between second transmission fiber 1041 of adjacent two, for adjusting
Save the polarization state of the terahertz laser pulse；The terahertz laser pulse is able to maintain preferable shape in Terahertz module 104
The frequency information of terahertz laser pulse can be fully retained in state transmission performance, ensured the job stability of Terahertz module 104
And job security.
Optionally, second optical attenuator 1043 is adopted with the second transmission fiber 1041 and is screwed, the second optical fiber
Polarization Controller 1044 is adopted with the second transmission fiber 1041 and is screwed；Therefore the optical fiber type bimodal imaging system 10
Structure more simplifies, and the volume of space hold is less, and the operation is more convenient, can be applicable to each different industrial technical field.
The fluorescent moieties 105 further include: at least one third fiber interface module 1052, the third optical fiber interface mould
Block 1052 is connected between the third transmission fiber 1051 of adjacent two, for being compatible with to the Fluorescence laser pulse
Transmission and the fixed third transmission fiber 1051；The third fiber interface module 1052 can specific optical power transmission
Fluorescence laser pulse can more fully be obtained the image information of sample 20 by the Fluorescence laser pulse, improve sample
The accuracy and stability of 20 fluorescence imaging.
Optionally, first optical fiber polarization controller 1024 is three paddle Polarization Controllers, the second optical fiber polarization controller
1044 be three paddle Polarization Controllers；It should be noted that the three paddles Polarization Controller is produced using birefringent caused by stress
Raw independent three beam splitting wave plates, and then change transmission fiber (including the first transmission fiber 1021 and second transmission fiber 1041)
The polarization direction of middle pulse；Three beam splitting wave plates are generated and along three independent spool wound fibers；For pre-
The Polarization Controller of dress optical fiber is equivalent to wave plate, the half-wave plate of an a quarter using three paddles in design wavelength
With the wave plate of a quarter；The online axial plane of the fast axle of transmission fiber can obtain arbitrary polarization direction by rotation oar,
Change the polarization state for obtaining laser pulse according to actual needs；Therefore the three paddles Polarization Controller can be realized linearly polarized light,
Conversion between circularly polarized light and elliptically polarized light this three, laser pulse and terahertz laser pulse are in optical fiber type bimodal
There is high Modulatory character and ease-to-operate, the optical fiber type bimodal imaging system 10 has higher in imaging system 10
Job stability, can accurately obtain 20 surface of sample and internal structural information by various types of light, it is easy to operate,
The detection sensitivity and accuracy of sample 20 are ensured.
As an alternative embodiment, Fig. 3 to Fig. 5 respectively illustrates the first optical fiber interface mould provided in this embodiment
The structural representation of 1052 this three of block 1022, the second fiber interface module 1042 and third fiber interface module, please refers to figure
3, first fiber interface module 1022 includes: sequentially connected first fibre-optical splice 301, the first optical fiber matching casing 302
And second fibre-optical splice 303；Wherein first fibre-optical splice 301 connects first transmission fiber 1021, second light
Fine connector 303 connects another first transmission fiber 1021；Two adjacent the first transmission fibers 1021 are able to maintain relatively steady
Fixed position and laser pulse keeps complete transmission state, the first fiber interface module in optical fiber transmission module 1022
1022 have lower manufacturing cost and structure application cost, and the laser pulse has higher signal transmission performance and transmission
Stability.
The first optical fiber matching casing 302 is for fixing first fibre-optical splice 301 and second fibre-optical splice
303。
Optionally, the notch casing that the first optical fiber matching casing 302 is 2.0mm, first optical fiber match casing 302
The polarization characteristic and transmission accuracy that can ensure laser pulse, can be improved laser pulse by the first fiber interface module 1022
Information integrity and can accuracy of measurement.
Optionally, the first fibre-optical splice 301 and the second fibre-optical splice 303 are all FC/APC fibre-optical splice, wherein the FC/
APC fibre-optical splice is a kind of optical fiber bar line of more standard, the compatible different types of fiber information of transmission, and FC/APC light
The manufacture material of fine connector is more universal and cheap, thereby reduces the manufacturing cost and application of the first fiber interface module 1022
Cost, laser pulse have higher efficiency of transmission and transmission precision, simplify the assembling step of the first fiber interface module 1022
Suddenly.
Referring to Fig. 4, second fiber interface module 1042 includes: sequentially connected third fibre-optical splice 304, second
Optical fiber matches casing 305 and the 4th fibre-optical splice 306；Wherein the third fibre-optical splice 304 connects second transmission fiber
1041, the 4th fibre-optical splice 306 connects another second transmission fiber 1041；In conjunction with third fibre-optical splice 304 and the 4th
Fibre-optical splice 306 can make the connection between a plurality of second transmission fiber 1041 more stable and reliable, and terahertz laser pulse exists
Higher effectiveness and Terahertz detection accuracy are kept in Terahertz module 1042.
The second optical fiber matching casing 305 is for fixing the third fibre-optical splice 304 and the 4th fibre-optical splice
306。
Optionally, the notch casing that the second optical fiber matching casing 305 is 2.0mm, matches casing by the second optical fiber
The terahertz laser pulse of 305 outputs more steadily can keep compatible transporting in a plurality of second transmission fiber 1041
Can, Terahertz module 104 has the efficiency of transmission and structure compatible performance of higher terahertz laser pulse, improves Terahertz
The scope of application of module 1042.
Referring to Fig. 5, the third fiber interface module 1052 includes: sequentially connected 5th fibre-optical splice 307, third
Optical fiber matches casing 308 and six fibers connector 309, wherein the 5th fibre-optical splice 307 connects the third transmission light
Fibre 1051, the six fibers connector 309 connects another third transmission fiber 1051；Wherein, in conjunction with the 5th fibre-optical splice 307
The structural soundness of third fiber interface module 1052 and the micromation of volume can be ensured with six fibers connector 309, work as third
Fiber interface module 1052 is applied in fluorescent moieties 105, with the biography of higher Fluorescence laser pulse inside fluorescent moieties 105
Defeated efficiency and transmission accuracy.
The third optical fiber matching casing 308 is for fixing the 5th fibre-optical splice 307 and the six fibers connector
309。
Optionally, the notch casing that third optical fiber matching casing 308 is 2.0mm；Wherein the 5th fibre-optical splice 307 and the 6th
Fibre-optical splice 309 is all FC/APC fibre-optical splice, and matching casing 308 by third optical fiber can make Fluorescence laser pulse with higher
Effectiveness, the Fluorescence laser pulse in transmission process have higher interference free performance, third optical fiber interface
The signal transmission performance of module 1052 and the precision of fluorescence imaging are higher.
As an alternative embodiment, the structure that Fig. 6 shows Terahertz module 104 provided in this embodiment is shown
Meaning, referring to Fig. 6, the Terahertz module 104 includes: the second beam splitter 1045, terahertz emission module 1046, Terahertz spy
Survey module 1047 and lock-in amplifier module 1048.
Second beam splitter 1045 is connected between two second transmission fibers 1041, for the thz laser
Pulse is split to obtain pump light and detection light.
Wherein the light energy of terahertz laser pulse can be changed in second beam splitter 1045, so that the second beam splitter 1045
Different types of light is exported, wherein the pump light can provide energy into the detection process of sample 20, ensures the knot of sample 20
Structure identifies accuracy and stability；The detection light has specific frequency, can drive Terahertz module 104 by detecting light
For the structure detection efficiency and structure detection precision with higher of sample 20.
Terahertz emission module 1046 is connected between two second transmission fibers 1041, for receiving the pumping
Light, and the THz wave is given off under the driving of the pump light.
Wherein, the pump light includes specific optical power, and the pump light keeps higher energy in transmission process
Quantity set moderate can drive terahertz emission module 1046 to keep normal working condition by the pump light, so that Terahertz spoke
The THz wave that module 1046 exports specific wavelength is penetrated, the formation efficiency and biography of the THz wave of Terahertz module 104 are improved
Defeated efficiency.
Terahertz detection module 1047 is connected between two second transmission fibers 1041, is used for transmission the detection
Light, and receive and act on the THz wave after the sample 20, make the detection light and THz wave phase separation, and be sent to
Imaging device 106 is analyzed.
Wherein terahertz emission module 1046 exports THz wave to sample 20, can be obtained completely by THz wave
The internal structural information of sample 20, and the terahertz due to the internal frequency characteristic of THz wave, after acting on sample 20
Hereby the characteristic information of wave can also change, then the characteristic information of the THz wave acted on after sample 20 and sample 20 also can
There are one-to-one relationships, then the THz wave given off according to sample 20 can accurately obtain the internal structure of sample 20
Information and shape information, the precision and sensitivity of detection are high；The terahertz of sample 20 is obtained according to terahertz detection module 1047
Hereby information, and then on the basis of structural information for not damaging sample 20, sample can be obtained by THz wave precisely in real time
The external morphology details of product 20 has ensured that Terahertz module 1046 stablizes the Terahertz detection accuracy of sample 20 and detection
Property.
Lock-in amplifier module 1048 is connect by the first cable 1049 with the terahertz detection module 1047, and is led to
It crosses the second cable 1050 to connect with the imaging device 106, for acquiring the THz wave after acting on the sample 20, and root
The terahertz signal is generated according to the THz wave after the sample 20 is acted on.
Wherein, lock-in amplifier module 1048 has the function of signal conversion and information integration, passes through lock-in amplifier mould
Block 1048 collects the Terahertz information of sample 20, and then show that each component exists in sample 20 according to the Terahertz information
The layout structure in space, then containing each side of sample 20 by the terahertz wave signal that lock-in amplifier module 1048 exports
Face structural information, and the present embodiment can be more conducive to the transmission and compatibility of Terahertz information by cable, reduce too
The transmission cost of Hz information, and then show that the form of sample 20 is thin completely according to the terahertz signal that the second cable 1050 exports
Information is saved, there are biggish detection errors for the details of morphology for avoiding for sample 20.
As an alternative embodiment, Fig. 7 shows the knot of lock-in amplifier module 1048 provided in this embodiment
Structure signal, referring to Fig. 7, the lock-in amplifier module 1048 include: preamplifier 501, lock-in amplifier 502 and
Adc data capture card 503.
Preamplifier 501 is connect by first cable 1049 with the terahertz detection module 1047, for adopting
Collect the THz wave after acting on the sample 20, generate electric current under the driving for acting on the THz wave after the sample 20
Signal, and the current signal is amplified.
Wherein, it can be ensured between preamplifier 501 and terahertz detection module 1047 too by the first cable 1049
Hz information transmission security and accuracy, and the preamplifier 501 can realize the conversion of signal form, and optical signal is turned
It is changed to electric signal, the internal structural information of sample 20 can be obtained by current signal, and the current signal can also be in locking phase
Amplifier module 1048 can transmission rate and compatibility faster, in order to obtain the more comprehensive structural information of sample 20；
The more complete information in sample 20 can be kept after the current signal is amplified, and then according to amplified current signal
Terahertz detection accuracy can be improved.
Lock-in amplifier 502 is connect with the preamplifier 501, for detecting the amplitude of the current signal；Wherein
The lock-in amplifier 502 has the function of the dynamic detection of signal amplitude, when the current signal is in various frequencies, complicated electricity
Magnetic environment, the lock-in amplifier 502 can obtain the current signal of specific frequency, with exclude other interference electromagnetic environments for
The amplitude measurement process of current signal interferes；The lock-in amplifier 502 has more the Terahertz information of current signal
High precision, so that Terahertz module 104 can be realized accurate detection for the details of morphology of sample 20 and for sample
20 internal structure slight change is distinguished in real time.
Adc data capture card 503 is connect with the lock-in amplifier 502, and passes through second cable 1050 and institute
The connection of imaging device 106 is stated, for obtaining the terahertz signal according to the amplitude of the current signal.Wherein adc data is adopted
Truck 503 can accurately collected current signal information, specific structural information is obtained by the amplitude of the current signal, then
Terahertz signal accurately includes the internal component information and metamorphosis situation of sample 20；It therefore can according to terahertz signal
Accurately restore the comprehensive structural informations such as details of morphology and the boundary profile distribution of sample 20.
As an alternative embodiment, Fig. 8 shows the knot of terahertz emission module 1046 provided in this embodiment
Structure signal, referring to Fig. 8, the terahertz emission module 1046 includes: a plurality of sequentially connected second transmission fiber
1041, at least one described second fiber interface module 1042, at least one first dispersion compensating fiber 1140, biased electrical pressing mold
Block 1141 and photoconductive radiating antenna 1142.
Wherein, second transmission fiber 1041 is used for transmission the pump light；It can be fast by the second transmission fiber 1041
Fast ground compatibly transmits corresponding pump light, and the efficiency of transmission of pump light is high, and avoids the pump light and be transmitted across
It is interfered in journey by noise information, so that pump light keeps higher transmission precision and transmission accuracy in transmission process.
Second fiber interface module 1042 is connected between second transmission fiber 1041 of adjacent two, and described second
Fiber interface module 1042 is used to carry out the pump light compatible transmission and fixed second transmission fiber 1041；Therefore
Terahertz emission module 1046 has more firm space structure, and pump light can be kept more in terahertz emission module 1046
Efficiently, compatible transmission, pump light can keep original signal radiation frequency in transmission process, improve terahertz emission mould
The scope of application and practical value of block 1046.
First dispersion compensating fiber 1140 is connected between second transmission fiber 1041 of adjacent two, for matching
And eliminate the dispersion of second transmission fiber 1041；The mistake transmitted in the second transmission fiber 1041 due to pump light
A degree of dispersion characteristics can be presented in Cheng Zhong, the second transmission fiber 1041, and the dispersion characteristics of the second transmission fiber 1041 can be done
The transmission precision and frequency accuracy of pump light are disturbed, therefore the second transmission fiber can be offset by the first dispersion compensating fiber 1140
1041 dispersion characteristics improve the light source transmission quality of pump light, are conducive to the structure parameter precision for promoting THz wave.
Optionally, the first dispersion compensating fiber 1140 is Hollow-Core Photonic Crystal Fibers；Add in Hollow-Core Photonic Crystal Fibers
The dispersion with dispersion opposite coincident needed for the second transmission fiber 1041, and the length of the Hollow-Core Photonic Crystal Fibers are entered
With material and the antipodal dispersion characteristics of the second transmission fiber 1041, to reach the dispersion for eliminating the second transmission fiber 1041
Purpose.
Bias voltage module 1141 is connect with the lock-in amplifier module 1048, for according to the lock-in amplifier mould
The modulating frequency that block 1048 exports generates bias voltage；Wherein lock-in amplifier module 1048 produces specific modulating frequency,
To drive bias voltage module 1141 to be in specified working condition, then the bias voltage module 1141 is exportable corresponding
Electric signal improves the control response speed of bias voltage module 1141；It can be terahertz emission module by the bias voltage
1046 provide corresponding electric field driven, and the detection efficiency of Terahertz is higher, and job stability is stronger.
Photoconductive radiating antenna 1142 is connect with second transmission fiber 1041, by third cable 1143 and it is described partially
The connection of voltage module 1141 is set, and is oppositely arranged with sample bin 30, for receiving the pump light, and in the bias voltage
Driving under give off the THz wave；Wherein, the sample bin 30 is for accommodating the sample 20；Sample bin 30 and photoelectricity
It leads and linear propagation of light can be achieved between radiating antenna 1142；Bias voltage is loaded at the both ends of the photoconduction radiating antenna 1142
When, photoconductive radiating antenna 1142 it is radiation-curable go out THz wave and output to sample 20, after interacting with sample 20 with
Obtain the Terahertz information of sample 20；Wherein, bias voltage is less than the voltage rating of photoconductive radiating antenna 1142, so that photoelectricity
Leading radiating antenna 1142 will not be breakdown；Sample can be accurately restored according to the THz wave that sample 20 in sample bin 30 exports
20 each details of morphology and constituent changes of contents；This embodiment passes through third cable 1143 transmission configuration electricity
Pressure is realized sample 20 by THz wave higher so that photoconductive radiating antenna 1142 has higher job stability
Terahertz detection accuracy and detection efficiency.
As an alternative embodiment, Fig. 9 shows the knot of terahertz detection module 1047 provided in this embodiment
Structure signal, referring to Fig. 9, the terahertz detection module 1047 includes: a plurality of sequentially connected second transmission fiber
1041, at least one second fiber interface module 1042, at least one second dispersion compensating fiber 1144, delay line device 1145
And photoconductive exploring antenna 1146.
Second transmission fiber 1041 is used for transmission the detection light；It can access second by the second transmission fiber 1041
The detection light that beam splitter 1045 exports can be compatible with the optical power of detection light by the second transmission fiber 1041, so that detection light
Loss-free transmission is kept in the second transmission fiber 1041, terahertz detection module 1047 can quickly and accurately obtain sample
20 THz wave information improves detection accuracy and Terahertz detection efficiency for the structural information of sample 20.
Second fiber interface module 1042 is connected between second transmission fiber 1041 of adjacent two, and described second
Fiber interface module 1042 is used to carry out the detection light compatible transmission and fixed second transmission fiber 1041；Wherein
Second fiber interface module 1042 can also keep the polarization characteristic of detection light, be able to maintain Terahertz information by detecting light
Accuracy, and then the internal structural information and form nuance information of sample 20 are obtained, Terahertz detection has higher simultaneous
Capacitive and the scope of application, detect light has farther away transmission range, Terahertz module 104 in a plurality of second transmission fiber 1041
Structure is more stable and electronic component layout is with more integrated.
Second dispersion compensating fiber 1144 is connected between second transmission fiber 1041 of adjacent two, for matching
And eliminate the dispersion of second transmission fiber 1041；It can compensate for detection light second by the second dispersion compensating fiber 1144
Caused effect of dispersion when transmitting in transmission fiber 1041, detection light have when transmitting between a plurality of second transmission fiber 1041
There are higher accuracy and efficiency of transmission, the terahertz detection module 1047 has higher THz wave detection accuracy, too
Hertz signal can reflect the details of morphology information of sample 20 precisely in real time.
Optionally, the second dispersion compensating fiber 1144 can be Hollow-Core Photonic Crystal Fibers；In Hollow-Core Photonic Crystal Fibers
It joined the dispersion with dispersion opposite coincident needed for the second transmission fiber 1041；And then light is detected in terahertz detection module
Transmission process anti-interference with higher in 1047 improves the Terahertz acquisition of information precision for sample 20, maximum
Degree reduces the information loss and deviation that detection light occurs in transmission process.
Delay line device 1145 is connected between second transmission fiber 1041 of adjacent two, for adjusting the pump
Relative delay between Pu light and the detection light；Optionally, the delay line device 1145 is fibre delay line, to adjust
It saves pump light and detects the transmission time difference between light, it, can essence in conjunction with the transmission time difference between detection light and pump light
The details of morphology information for really obtaining sample 20 realizes the real-time acquisition of the various dimensions characteristic information for sample 20；Terahertz
Hereby module 104 there is higher Terahertz to detect stability, the detection of the Terahertz of sample 20 structural information of sample 20
Process has higher adjustability.
Optionally, the delay line device 1145 passes through cable connection with imaging device 106, and then imaging device 106 can
The delay transmission time of control detection light adjusts pump light and detects the transmission time difference between light, and then imaging device 106
The form profile that can show sample 20 more accurately has ensured the sample message detection of optical fiber type bimodal imaging system 10
Precision and sample structure information Terahertz detection efficiency.
Optionally, the second dispersion compensating fiber 1144 may be provided between the second beam splitter 1045 and delay line device 1145
Optical path so that delay line device 1145 plays optimal detection light transmissioning efficiency and adjustment state.
Photoconductive exploring antenna 1146 is connect with second transmission fiber, and is oppositely arranged with sample bin 30, is used for
THz wave after acting on the sample 20 according to the detection light-receiving；Wherein, the sample bin 30 is described for accommodating
Sample 20；Photoconductive exploring antenna 1146 connects lock-in amplifier module 1048 by the first cable 1049, which detects day
The THz wave that line 1146 will act on after sample 20 is exported to lock-in amplifier module 1048, and then the lock-in amplifier module
1048 can obtain the Terahertz information of sample 20 completely, realize the high-precision detection and analysis for morphosis in sample 20；
Optionally, the photoconductive exploring antenna 1146 includes that multilayer InGaAs (indium GaAs) is deposited on InP (phosphatization
Indium) butterfly-like dipole antenna is formed on substrate.When detection light radiation generates photoproduction current-carrying among butterfly-like dipole antenna gap
Son, and receive act on the THz wave after sample 20 simultaneously, photoconductive exploring antenna 1146 believes the Terahertz of sample 20
Breath has high detectivity and accuracy, so that the photoconduction exploring antenna 1146 can obtain sample 20 in real time
Internal structural information, the rate of THz wave imaging and the precision of imaging are higher, and the THz wave after acting on sample 20 can
It is phase locked the acquisition of amplifier module 1048 completely, the Terahertz information of sample 20 is avoided to be missed and damaged in transmission process
Consumption.
Second beam splitter 1045 has the function of terahertz laser pulse beam splitting, to realize the generation and inspection of THz wave
Brake；Optionally, there are the controls of the second optical fiber polarisation in the optical path between the first beam splitter 103 and the second beam splitter 1045
Device 1044 and the second optical attenuator 1043,1043 phase interworking of second optical fiber polarization controller 1044 and the second optical attenuator
Work is closed, changes the polarization of terahertz laser pulse in conjunction with the second optical fiber polarization controller 1044 and the second optical attenuator 1043
The optical power of characteristic, to adjust the beam splitting ratio of the second beam splitter 1045；Since photoconductive radiating antenna 1142 and photoconduction are visited
Pulse optical power required for observation line 1146 is not identical, by the pump light and the detection that adjust the output of the second beam splitter 1045
Ratio between light prevents the optical power of laser pulse (detection light and pump light) from exceeding photoconductive radiating antenna 1142 and photoelectricity
The rated power that both exploring antennas 1146 are carried is led, the beam splitting of the pump light and detection light of flexibly adjustment incidence is passed through
Ratio protects photoconductive radiating antenna 1142 and photoconductive exploring antenna 1146；So enter terahertz emission module
Optical power ratio between pump light in 1046 and the detection light for entering terahertz detection module 1047 can also occur adaptive
It should change, can have higher detection accuracy, the terahertz of sample 20 for the morphosis of sample 20 by Terahertz module 104
Hereby detection can be at optimal working condition and interference free performance.
As an alternative embodiment, Figure 10 shows the structural representation of fluorescent moieties 105 provided in this embodiment,
Referring to Fig. 10, the fluorescent moieties 105 include: third dispersion compensating fiber 1147, optical-fiber bundling device 1148, optical fiber collimator
1149, optical imaging objective 1150, multimode signal optical fiber 1151, bandpass filter 1152 and photomultiplier tube 1153.
Wherein, third dispersion compensating fiber 1147 is connected between two third transmission fibers 1051, for matching
And eliminate the dispersion of the third transmission fiber 1051；Third transmission fiber can be ensured by third dispersion compensating fiber 1147
The stability of the light characteristic of Fluorescence laser pulse in 1051, by third dispersion compensating fiber 1147 for Fluorescence laser pulse into
After row dispersion compensation, the Fluorescence laser pulse that the third dispersion compensating fiber 1147 exports has specific pulsewidth, can be the
Three fiber interface modules 1052 directly carry out compatible transmission.
Optionally, third dispersion compensating fiber 1147 is Hollow-Core Photonic Crystal Fibers.It is added in Hollow-Core Photonic Crystal Fibers
Dispersion with dispersion opposite coincident needed for third transmission fiber 1051；The third dispersion compensating fiber 1147 is using certainly
The material property of body can be completely counterbalanced by the dispersion characteristics in third transmission fiber 1051.
Optical-fiber bundling device 1148 is connect with the third transmission fiber 1051, for closing to the Fluorescence laser pulse
At and transmit；Optionally, the optical-fiber bundling device 1148 is (2+1) × 1 optical-fiber bundling device, which is multimode
Pumping+signal light combiner, input terminal include two pump ports and a polarization-maintaining signal port, and output end is a double clad
Fiber port is made of fused biconical taper technique, has special optical property, and low-loss fluorescence transmission may be implemented；It can
Choosing, in fluorescent moieties 105, the pump ports of the input terminal of optical-fiber bundling device 1148 connect third transmission fiber 1051, light
The polarization-maintaining signal port of the input terminal of fine bundling device 1148 connects multimode signal optical fiber 1151, the output end of optical-fiber bundling device 1148
Doubly clad optical fiber 1154 is connected, and then optical-fiber bundling device 1148 can realize the compatible transmission function of fluorescence information.
Optical fiber collimator 1149 connects the optical-fiber bundling device 1148 by doubly clad optical fiber 1154, for the fluorescence
Laser pulse transmits after being collimated；Doubly clad optical fiber 1154 can retain in the Fluorescence laser pulse of the output of optical-fiber bundling device 1148
All characteristic informations；Fluorescence laser pulse can be made to realize directional light conversion by optical fiber collimator 1149, there is higher biography
Defeated efficiency and transmission precision, prevent Fluorescence laser pulse from different source noises occur, and sample 20 is subjected to more stable
Fluorescence information.
Optical imaging objective 1150 is connect with the optical fiber collimator 1149, and is oppositely arranged with the sample bin 30,
For will be imaged in the Fluorescence laser pulse concentration to the sample 20 after collimation；Wherein the sample bin 30 is for accommodating
The sample 20；After being focused Fluorescence laser pulse by optical imaging objective 1150, be conducive to promote Fluorescence laser
The power centrality of pulse；There is light source linear transmission path, then fluorescence between optical imaging objective 1150 and sample bin 30
Laser pulse can utmostly focus on sample 20 and generate fluorescence signal, and the fluorescence signal being reflected back according to sample 20
The morphological image information for accurately obtaining sample 20, the fluorescence signal received by optical imaging objective 1150 can be obtained accurately
The image of internal structure information of sample 20 out.
In the inside optical path of fluorescent moieties 105, the fluorescence signal that sample 20 issues passes sequentially through optical imaging objective
1150, until reaching optical-fiber bundling device 1148, optical-fiber bundling device 1148 is also used to for optical fiber collimator 1149, doubly clad optical fiber 1154
Collect the fluorescence signal that the sample 20 issues under the excitation of the Fluorescence laser pulse；So optical-fiber bundling device
1148 have concentrated all fluorescence informations of sample 20, and fluorescence signal transmits between different electronic components has higher effect
Rate can realize that comprehensive, high-precision detects for each details of morphology of sample 20, the CONSTRUCTED SPECIFICATION of sample 20 is become
Changing measurer has higher detection sensitivity.
Multimode signal optical fiber 1151 is connect with the optical-fiber bundling device 1148, is used for transmission the fluorescence signal；Due to glimmering
Optical signal includes the multichannel characteristic information of sample 20, therefore being capable of real-time guarantees fluorescence signal biography by multimode signal optical fiber 1151
There is the internal structure of defeated integrality and compatibility, the fluorescent moieties 105 higher fluorescence information to transmit accuracy.
Bandpass filter 1152 is connect with the multimode signal optical fiber 1151, is carried out for the wavelength to the fluorescence signal
Filtering；Optionally, bandpass filter 1152 be broad band pass filter or narrow band filter, can basis by bandpass filter 1152
The actual demand of technical staff changes the wavelength of light source, therefore fluorescence signal can be selected by bandpass filter 1152
Property filtering, retain sample 20 complete structure information；And then sample 20 is parsed completely in the filtered fluorescence signal of wavelength
Spatial structural form, promote the compatibility and accuracy of fluorescence imaging.
Photomultiplier tube 1153 is connect with the bandpass filter 1152, passes through the 4th cable 1155 and the imaging device
106 connections, for acquiring wavelength through the filtered fluorescence signal of bandpass filter 1152；The wherein detection of photomultiplier tube 1153
The actual wavelength of wavelength and fluorescence signal matches；Optionally, photomultiplier tube 1153 can be by fluorescence signal with the shape of electric signal
Formula is exported, and in ensureing fluorescence signal on the basis of characteristic information integrality, fluorescence imaging has higher processing speed
Rate；When photomultiplier tube 1153 is exported fluorescence signal to imaging device 106 by the 4th cable 1155, imaging device 106
After identifying for the fluorescence signal, morphological feature therein is directly extracted, and then obtains the integrity profile structure of sample 20,
Complete fluorescence imaging function.
In conclusion optical fiber type bimodal imaging system 10 provided in an embodiment of the present invention, with the replacement of optical fiber type optical transport
THz wave imaging and fluorescence imaging are carried out accurate coupling by traditional free-space optical transmission, construct compact-sized stabilization,
Integration degree is high, strong functional optical fiber type bimodal imaging system 10；It can be with using optical fiber type bimodal imaging system 10
The terahertz signal and fluorescence signal of sample 20 are obtained simultaneously, carry out positioning analysis from big dimension and to provide necessary form thin
Section, to realize signal acquisition and the analysis of different dimensions, solve previous independent system acquisition information amount it is single, using model
Enclose the limited and not high problem of stability.
Figure 11 shows the specific implementation step of optical fiber type bimodal imaging method provided in this embodiment, please refers to figure
11, the optical fiber type bimodal imaging method specifically includes:
Step S901: obtaining and transmits laser pulse.
Step S902: the laser pulse is split to obtain terahertz laser pulse and Fluorescence laser pulse.
Step S903: the terahertz laser pulse is split and is transmitted to obtain THz wave, and by described in too
Interaction occurs for Hertz wave and sample to generate terahertz signal.
Step S904: receiving the Fluorescence laser pulse, and by the Fluorescence laser pulse concentration in the sample to produce
Raw fluorescence signal.
Step S905: the terahertz signal and the fluorescence signal are coupled to obtain the multidimensional of sample letter
Breath.
It should be noted that the specific steps of optical fiber type bimodal imaging method and Fig. 1 optical fiber type into Figure 10 in Figure 11
Bimodal imaging system 10 is corresponding, thus close in this present embodiment in optical fiber type bimodal imaging method each step it is specific
Embodiment can refer to the embodiment of Fig. 1 to Figure 10, will not be described in great detail herein；Therefore the optical fiber type bimodal imaging method is logical
The advantages of combining both THz wave imaging and fluorescence imaging is spent, the form of each dimension of sample can be obtained more accurately
Details and constituent characteristic improve detection sensitivity and accuracy of detection for sample, can be widely applicable for each
Different industrial technical fields, the image quality for improving sample have positive facilitation；Efficiently solve tradition
The problem that the information content that technology obtains sample is single, stability is not high.
Various embodiments are described to various devices, circuit, device, system and or method herein.It elaborates very much
Specific details is to provide general construction, the function, system of the embodiment that the sum as described in the description is shown in the accompanying drawings
The thorough understanding made and used.However it will be understood by those skilled in the art that embodiment can be in not such certain detail
It is carried out in the case where section.In other examples, well known operation, component and element is described in detail, in order to avoid make in specification
In embodiment indigestion.It will be understood by those skilled in the art that being unrestricted in the embodiment with shown in herein
Property example, and therefore it can be appreciated that, can be in specific structure and function details disclosed herein representative and and different
The range of definite limitation embodiment.
Throughout the specification to " various embodiments ", " in embodiments ", " embodiment " or " embodiment party
The reference of formula " etc., which is meant, is included at least one embodiment about a particular feature, structure, or characteristic described in embodiment
In.Therefore, phrase " in various embodiments ", " in some embodiments ", " in one embodiment " or " implementing
In mode " etc. the appearance in appropriate place throughout the specification be not necessarily all referring to same embodiment.In addition, specific spy
Sign, structure or characteristic can combine in any suitable manner in one or more embodiments.Implement accordingly, with respect to one
The a particular feature, structure, or characteristic that mode shows or describes can entirely or partly with one or more of the other embodiment spy
Sign, structure or characteristic are combined, without assuming that such combination is not illogical or non-functional limitation.Any side
To with reference to (for example, add, subtract, top, lower part, upwards, downwards, the left side, the right, to the left, to the right, top, bottom ...
On ... under, it is vertical, horizontal, clockwise and anticlockwise) purpose to be for identification to help reader to understand present disclosure,
And limitation is not generated, especially with regard to the position of embodiment, orientation or use.
Although describing certain embodiments above with some the level of detail, those of skill in the art can be to institute
Disclosed embodiment makes many changes without departing from the scope of the present disclosure.Connection is with reference to (for example, attachment, coupling, connection
Deng) should be widely interpreted, and may include the intermediate member between the connection of element and relative motion between elements.Cause
This, connection reference does not necessarily imply that two elements are directly connected to/couple and are in fixed relationship each other." such as " entire
Use in specification should be widely interpreted and for providing the non-limitative example of embodiment of the present disclosure, and the disclosure
It is not limited to such example.Being intended that all affairs for including in the foregoing description or be shown in the accompanying drawings should be interpreted only
It is illustrative rather than restrictive.The variation in details or structure can be made without departing from the disclosure.
The above is merely preferred embodiments of the present invention, be not intended to limit the invention, it is all in spirit of the invention and
Made any modifications, equivalent replacements, and improvements etc., should all be included in the protection scope of the present invention within principle.
Claims (10)
1. a kind of optical fiber type bimodal imaging system characterized by comprising
For issuing the optical fiber laser of laser pulse；
It is connect with the optical fiber laser, is used for transmission the optical fiber transmission module of the laser pulse；
It is connect with the optical fiber transmission module, for being split the laser pulse to obtain terahertz laser pulse and fluorescence
First beam splitter of laser pulse；
It is connect with first beam splitter, for the terahertz laser pulse to be split and transmitted to obtain Terahertz
Wave, and the THz wave and sample are had an effect to obtain the Terahertz module of terahertz signal；
It connect with first beam splitter, exists for receiving the Fluorescence laser pulse, and by the Fluorescence laser pulse concentration
The sample is to generate the fluorescent moieties of fluorescence signal；And
It is connect with the Terahertz module and the fluorescent moieties, for being carried out to the terahertz signal and the fluorescence signal
It couples to obtain the imaging device of the multidimensional information of the sample.
2. optical fiber type bimodal imaging system according to claim 1, which is characterized in that the optical fiber transmission module packet
It includes: a plurality of the first transmission fiber that is sequentially connected, being used for transmission the laser pulse；
The Terahertz module include: it is a plurality of sequentially connected, be used for transmission the terahertz laser pulse second transmission light
It is fine；
The fluorescent moieties include: it is a plurality of sequentially connected, be used for transmission the third transmission fiber of the Fluorescence laser pulse.
3. optical fiber type bimodal imaging system according to claim 2, which is characterized in that the optical fiber transmission module also wraps
It includes:
At least one, be connected between first transmission fiber of adjacent two, for being compatible with to the laser pulse
First fiber interface module of transmission and fixed first transmission fiber；
At least one, be connected between first transmission fiber of adjacent two, the light function for the laser pulse of decaying
First optical attenuator of rate；And
At least one, be connected between first transmission fiber of adjacent two, for adjusting the polarization of the laser pulse
First optical fiber polarization controller of state；
The Terahertz module further include:
At least one, be connected between second transmission fiber of adjacent two, for the terahertz laser pulse into
Second fiber interface module of row compatible transmission and fixed second transmission fiber；
At least one, be connected between second transmission fiber of adjacent two, for adjusting the terahertz laser pulse
Optical power the second optical attenuator；And
At least one, be connected between second transmission fiber of adjacent two, for adjusting the terahertz laser pulse
Polarization state the second optical fiber polarization controller；
The fluorescent moieties further include:
At least one, be connected between the third transmission fiber of adjacent two, for the Fluorescence laser pulse carry out
The third fiber interface module of compatible transmission and the fixed third transmission fiber.
4. optical fiber type bimodal imaging system according to claim 3, which is characterized in that first fiber interface module
It include: sequentially connected first fibre-optical splice, the first optical fiber matching casing and the second fibre-optical splice；Wherein first optical fiber
Connector connects first transmission fiber, and second fibre-optical splice connects another first transmission fiber；
The first optical fiber matching casing is for fixing first fibre-optical splice and second fibre-optical splice；
Second fiber interface module includes: sequentially connected third fibre-optical splice, the second optical fiber matching casing and the 4th
Fibre-optical splice；Wherein the third fibre-optical splice connects second transmission fiber, and the 4th fibre-optical splice connects another described
Two transmission fibers；
The second optical fiber matching casing is for fixing the third fibre-optical splice and the 4th fibre-optical splice；
The third fiber interface module includes: sequentially connected 5th fibre-optical splice, third optical fiber matching casing and the 6th
Fibre-optical splice, wherein the 5th fibre-optical splice connects a third transmission fiber, the six fibers connector connects another described
Third transmission fiber；
The third optical fiber matching casing is for fixing the 5th fibre-optical splice and the six fibers connector.
5. optical fiber type bimodal imaging system according to claim 4, which is characterized in that the Terahertz module includes:
It is connected between two second transmission fibers, for being split to obtain pump light to the terahertz laser pulse
With the second beam splitter of detection light；
It is connected between two second transmission fibers, for receiving the pump light, and under the driving of the pump light
Give off the terahertz emission module of the THz wave；
It is connected between two second transmission fibers, is used for transmission the detection light, and receive and act on the sample
The terahertz detection module of THz wave afterwards；And
It is connect by the first cable with the terahertz detection module, and is connect by the second cable with the imaging device,
For acquiring the THz wave after acting on the sample, and according to act on the THz wave after the sample generate it is described too
The lock-in amplifier module of hertz signal.
6. optical fiber type bimodal imaging system according to claim 5, which is characterized in that the lock-in amplifier module packet
It includes:
It is connect by first cable with the terahertz detection module, for acquiring the Terahertz after acting on the sample
Wave generates current signal under the driving for acting on the THz wave after the sample, and the current signal is amplified
Preamplifier；
It is connect with the preamplifier, the lock-in amplifier of the amplitude for detecting the current signal；And
It connect with the lock-in amplifier, and is connect by second cable with the imaging device, for according to
The amplitude of current signal obtains the adc data capture card of the terahertz signal.
7. optical fiber type bimodal imaging system according to claim 5, which is characterized in that the terahertz emission module packet
It includes:
A plurality of sequentially connected second transmission fiber, second transmission fiber are used for transmission the pump light；
At least one, second fiber interface module being connected between second transmission fiber of adjacent two, it is described
Second fiber interface module is used to carry out the pump light compatible transmission and fixed second transmission fiber；
At least one, be connected between second transmission fiber of adjacent two, for match and eliminate it is described second pass
Lose the first dispersion compensating fiber of fine dispersion；
It is connect with the lock-in amplifier module, the modulating frequency for being exported according to the lock-in amplifier module generates biasing
The bias voltage module of voltage；And
Connect with second transmission fiber, connect by third cable with the bias voltage module, and with sample bin phase
To setting, for receiving the pump light, and the photoconduction of the THz wave is given off under the driving of the bias voltage
Radiating antenna；Wherein, the sample bin is for accommodating the sample.
8. according to optical fiber type bimodal imaging system described in claim 5 to 7 any one, which is characterized in that the terahertz
Hereby detecting module includes:
A plurality of sequentially connected second transmission fiber, second transmission fiber are used for transmission the detection light；
At least one, second fiber interface module being connected between second transmission fiber of adjacent two, it is described
Second fiber interface module is used to carry out the detection light compatible transmission and fixed second transmission fiber；
At least one, be connected between second transmission fiber of adjacent two, for match and eliminate it is described second pass
Lose the second dispersion compensating fiber of fine dispersion；
It is connected between second transmission fiber of adjacent two, for adjusting between the pump light and the detection light
The delay line device of relative delay；And
It connect with second transmission fiber, and is oppositely arranged with sample bin, for being acted on according to the detection light-receiving
The photoconductive exploring antenna of THz wave after the sample；Wherein, the sample bin is for accommodating the sample.
9. optical fiber type bimodal imaging system according to claim 3, which is characterized in that the fluorescent moieties further include:
It is connected between two third transmission fibers, of the dispersion for matching and eliminating the third transmission fiber
Three dispersion compensating fibers；
It is connect with the third transmission fiber, the optical-fiber bundling device for the Fluorescence laser pulse to be synthesized and transmitted；
Wherein, the optical-fiber bundling device is also used to collect described in the sample issues under the excitation of the Fluorescence laser pulse
Fluorescence signal；
The optical-fiber bundling device is connected by doubly clad optical fiber, the light for transmitting after collimating to the Fluorescence laser pulse
Fine collimator；
It connect with the optical fiber collimator, and is oppositely arranged with the sample bin, for the Fluorescence laser pulse after collimating
Focus to the optical imaging objective being imaged on the sample；Wherein the sample bin is for accommodating the sample；
It is connect with the optical-fiber bundling device, is used for transmission the multimode signal optical fiber of the fluorescence signal；
It is connect with the multimode signal optical fiber, the bandpass filter being filtered for the wavelength to the fluorescence signal；And
It is connect with the bandpass filter, is connect by the 4th cable with the imaging device, filtered for acquiring wavelength through band logical
The photomultiplier tube of the filtered fluorescence signal of mating plate.
10. a kind of optical fiber type bimodal imaging method characterized by comprising
It obtains and transmits laser pulse；
The laser pulse is split to obtain terahertz laser pulse and Fluorescence laser pulse；
The terahertz laser pulse is split and is transmitted to obtain THz wave, and the THz wave and sample are sent out
Raw interaction is to generate terahertz signal；
Receive the Fluorescence laser pulse, and by the Fluorescence laser pulse concentration in the sample to generate fluorescence signal；With
And
The terahertz signal and the fluorescence signal are coupled to obtain the multidimensional information of the sample.
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