CN108078569A - The Dynamic Blood Glucose Monitoring instrument and its control method of a kind of cell phone application direct monitoring - Google Patents

The Dynamic Blood Glucose Monitoring instrument and its control method of a kind of cell phone application direct monitoring Download PDF

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Publication number
CN108078569A
CN108078569A CN201611022085.9A CN201611022085A CN108078569A CN 108078569 A CN108078569 A CN 108078569A CN 201611022085 A CN201611022085 A CN 201611022085A CN 108078569 A CN108078569 A CN 108078569A
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China
Prior art keywords
blood glucose
module
transmitter
monitoring
mobile phone
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CN201611022085.9A
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Chinese (zh)
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吴伟华
肖林春
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Nantong Nine Connaught Medical Technology Co Ltd
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Nantong Nine Connaught Medical Technology Co Ltd
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Priority to CN201611022085.9A priority Critical patent/CN108078569A/en
Publication of CN108078569A publication Critical patent/CN108078569A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14532Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0002Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network
    • A61B5/0004Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network characterised by the type of physiological signal transmitted
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0002Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network
    • A61B5/0015Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network characterised by features of the telemetry system
    • A61B5/0022Monitoring a patient using a global network, e.g. telephone networks, internet
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/103Detecting, measuring or recording devices for testing the shape, pattern, colour, size or movement of the body or parts thereof, for diagnostic purposes
    • A61B5/11Measuring movement of the entire body or parts thereof, e.g. head or hand tremor, mobility of a limb
    • A61B5/1116Determining posture transitions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1455Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/68Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6846Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/74Details of notification to user or communication with user or patient ; user input means
    • A61B5/746Alarms related to a physiological condition, e.g. details of setting alarm thresholds or avoiding false alarms
    • HELECTRICITY
    • H04ELECTRIC COMMUNICATION TECHNIQUE
    • H04MTELEPHONIC COMMUNICATION
    • H04M1/00Substation equipment, e.g. for use by subscribers
    • H04M1/72Mobile telephones; Cordless telephones, i.e. devices for establishing wireless links to base stations without route selection
    • H04M1/724User interfaces specially adapted for cordless or mobile telephones
    • H04M1/72403User interfaces specially adapted for cordless or mobile telephones with means for local support of applications that increase the functionality
    • HELECTRICITY
    • H04ELECTRIC COMMUNICATION TECHNIQUE
    • H04MTELEPHONIC COMMUNICATION
    • H04M1/00Substation equipment, e.g. for use by subscribers
    • H04M1/72Mobile telephones; Cordless telephones, i.e. devices for establishing wireless links to base stations without route selection
    • H04M1/724User interfaces specially adapted for cordless or mobile telephones
    • H04M1/72403User interfaces specially adapted for cordless or mobile telephones with means for local support of applications that increase the functionality
    • H04M1/72409User interfaces specially adapted for cordless or mobile telephones with means for local support of applications that increase the functionality by interfacing with external accessories
    • H04M1/72415User interfaces specially adapted for cordless or mobile telephones with means for local support of applications that increase the functionality by interfacing with external accessories for remote control of appliances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2560/00Constructional details of operational features of apparatus; Accessories for medical measuring apparatus
    • A61B2560/02Operational features
    • A61B2560/0204Operational features of power management
    • A61B2560/0214Operational features of power management of power generation or supply
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/02Details of sensors specially adapted for in-vivo measurements
    • A61B2562/0219Inertial sensors, e.g. accelerometers, gyroscopes, tilt switches

Abstract

The Dynamic Blood Glucose Monitoring instrument and its control method of a kind of cell phone application direct monitoring, it is related to the wearable device and its control method for medical science, including Wearable blood glucose transmitter, the high in the clouds storage that mobile phone APP terminal is connected with by mobile phone APP terminal, blood glucose transmitter is connected with emitter assemblies by blood glucose sensor component and formed, and mobile phone APP terminal is connected to blood glucose transmitter by bluetooth mode;Mobile phone APP terminal is connected to high in the clouds by mobile communication network and stores;The network share of glucose monitor data is realized by being pushed to authorized user, it can be while continuous acquisition and record blood sugar for human body, movement and the sleep info of wearer is obtained by 3-axis acceleration sensor, the identification for providing hypoglycemic coma is saved oneself with wake-up, glucose monitor data is sent to the intelligent handheld device of radio transmission-receiving function or other external reception terminals by wireless transmission mode, displays data analysis and remote-end alarm emergency service.

Description

The Dynamic Blood Glucose Monitoring instrument and its control method of a kind of cell phone application direct monitoring
Technical field
The present invention relates to the wearable device for medical science and its control methods more particularly to one kind to be used to move State blood glucose measurement and the electronic circuit and its body-worn device of athletic posture detection.
Background technology
Blood sugar monitoring is the important component in diabetes management, and the result of blood sugar monitoring helps to assess patient of diabetes The degree of person's carbohydrate metabolism disturbance specifies hypoglycemic scheme, while the effect for showing treatment and guides the adjustment to therapeutic scheme.Blood glucose Concentration is related with several factors, such as moves, diet, medication etc..Traditional blood sugar monitoring methods are that acquisition refers to blood monitoring, but this Method can not react patient's whole day blood glucose collection of illustrative plates, and there are monitoring blind areas.Therefore, developed recently goes out a kind of Dynamic Blood Glucose Monitoring production Product can realize the blood sugar monitoring of whole day.For example, Chinese invention patent application " implanted low-consumption wireless blood sugar monitoring instrument " (application for a patent for invention number:201410277574.3 publication number:CN104055525A a kind of implanted low-consumption wireless) is disclosed Blood sugar monitoring instrument, including et al. Ke component and external component, the et al. Ke component includes implantable glucose sensor, The implantable glucose sensor is connected with signal processing circuit, and the signal processing circuit is connected with microprocessor, described Microprocessor is connected with the first wireless communication module, the implantable glucose sensor, and the signal processing circuit is described micro- Processor and first wireless communication module are all connected with power supply module, the signal processing circuit, the microprocessor institute It states wireless communication module and the power supply module all coats inside the shell;The external component include the second wireless communication module and Host computer, second wireless communication module are connected with the host computer.A kind of Chinese utility model patent " wireless, real-time blood Sugared recorder " (utility model patent number:ZL201520192338.1 Authorization Notice No.:CN204618248U a kind of nothing) is disclosed Line, real time blood sugar recorder, are mainly made of monitoring side and APP terminals, and the monitoring side includes glucose inductive probe And wireless data transmitter;The wireless data transmitter is connected with glucose inductive probe, and by glucose inductive probe The blood glucose level data of offer reaches APP terminals;The APP terminals can analyze blood glucose level data and be shown on APP terminal screens Blood sugar concentration.When glucose inductive probe detects electric current, electric signal numerical value is closely sent to APP by wireless data transmitter Terminal, APP terminals can analyze blood glucose level data and blood sugar concentration, generation data and curves shown on APP terminal screens, are provided just True insulin dosage.The technical solution can realize 24 it is small when monitor blood sugar concentration in real time;By wireless transmission, can effectively solve Implantation subcutaneous position is too low to cause the problem of loosening of popping one's head in;Pass through APP terminal data processings, it is possibility to have effect solves equipment and carries Inconvenient, flimsy problem.
Although above-mentioned prior art solves the continuous real-time test problems of blood glucose, realize blood sugar in diabetic patients Horizontal dynamic monitoring.But such dynamic glucose product function is single, is only used for monitoring blood sugar for human body.And with blood glucose phase The information such as the movement of pass, diet, medication can only be recorded manually.Chinese utility model patent " wireless blood glucose meter walks instrument " (utility model patent number:ZL201220166396.3 Authorization Notice No.:CN202568265U) disclose a kind of with wireless biography The blood-glucose meter step instrument of transmission function.It is to connect Keysheet module and display module, main control module respectively through main control module by power module Blood glucose measurement module, note step module wireless transport module and memory module are connected respectively, and power module is above-mentioned module for power supply.Note Step records simultaneously with glucose monitor data, and data are wirelessly transmitted to host computer according to one day or week age interval stores With analysis.Blood glucose value and amount of exercise are monitored simultaneously, and with wireless transmission function, not only contribute to user to blood glucose value Long term monitoring and tracking can also be diabetic and its people at highest risk by analyzing the relation between blood glucose and amount of exercise Kinesiatrics is formulated, so as to delay or reduce the generation of diabetes and its complication.
Although above-mentioned prior art solves blood glucose value and some technical problems of amount of exercise monitoring respectively, These prior arts perform blood sugar test using according to default time interval, and note step module therein is also only will The function of pedometer is simply integrated into blood glucose meter, is used to implement the amount of exercise record of wearer, does not embody the two in function On mutual support.
On the other hand, hypoglycemic coma is most common and most important complication in Course of Diabetes Treatment.Hypoglycemia Stupor is that venous plasma concentration of glucose is less than patient's stupor caused during 2.8mmol/L (50mg/dl).With diabetes disease The day for human beings becomes to increasing and aging of population old age hypoglycemic coma patient increases year by year, is counted according to certain emergency department of institute over 5 years, emergency treatment is just The old stupor person examined accounts for 9%-12%, and which part patient obtains due to medical morning and treats in time, and another part patient is but because of hair Now with medical delay treatment not in time, cause irreversible cerebral lesion even dead.Therefore, hypoglycemic coma must carry out promptly A kind of wearable smart machine that disclosure satisfy that diabetic's nursing need is badly in need of in processing.
The content of the invention
The object of the present invention is to provide a kind of Dynamic Blood Glucose Monitoring instrument of cell phone application direct monitoring, can be in continuous acquisition While with record blood sugar for human body, movement and the sleep info of wearer are obtained, provides the identification of hypoglycemic coma with waking up certainly Rescue, and by way of wireless transmission by glucose monitor data be sent to the intelligent handheld device of radio transmission-receiving function or its His host computer terminal displays data analysis and remote-end alarm emergency service.
Technical solution is used by the present invention solves above-mentioned technical problem:
A kind of Dynamic Blood Glucose Monitoring instrument of cell phone application direct monitoring, including a Wearable blood glucose transmitter, as dynamic At least one mobile phone APP terminal of state blood sugar monitoring exterior terminal and the high in the clouds connected by mobile phone APP terminal store, It is characterized in that:
The blood glucose transmitter is connected with emitter assemblies by the blood glucose sensor component of built-in blood glucose sensor and formed; The emitter assemblies include sensor excitation module, sample conditioning module, ADC module, wireless SoC modules and acceleration It spends sensor assembly and motor wakes up alarm module;The sensor excitation module applies driving voltage to blood glucose sensor On;The sampling conditioning module by the conditioning of the current signal of blood glucose sensor into the matched voltage signal of ADC module;ADC Voltage signal after conditioning is converted into being sent to the main control chip of the wireless SoC modules of transmitter, master control core after digital signal by module Piece calculates blood sugar concentration according to the digital signal of sample conversion, is sent out by being integrated in wireless SoC moulds bluetooth BLE modules in the block It is sent to mobile phone APP terminal;The acceleration sensor module is connected to wireless SoC modules, obtains the movement and sleep of human body Information realizes that the identification of hypoglycemic coma and wake-up are saved oneself and alert help function;
The mobile phone APP terminal is connected to blood glucose transmitter by bluetooth mode, realizes the dynamic monitoring of blood sugar concentration; The mobile phone APP terminal is connected to high in the clouds by mobile communication network and stores;
The high in the clouds storage is used for storing the blood glucose level data of blood glucose transmitter acquisition, and by being pushed to authorized user Realize the network share of glucose monitor data.
A kind of preferable technical solution of the Dynamic Blood Glucose Monitoring instrument of the cell phone application direct monitoring of the present invention, feature exist In further including at least one distal end APP terminals as Dynamic Blood Glucose Monitoring exterior terminal;The distal end APP terminals are at least wrapped Include blood glucose level data monitoring module, blood glucose level data statistical analysis module and nursing relief alarm module;When mobile phone APP terminal licenses to After the APP terminals of distal end, distal end APP terminals receive the data that blood glucose transmitter is uploaded by mobile phone APP terminal, realize blood glucose hair The strange land monitoring and statistical analysis of emitter;The nursing relief alarm module receives the nursing relief that mobile phone APP terminal is sent Warning message realizes the distal end nursing relief alert service of hypoglycemic coma.
A kind of superior technique scheme of the Dynamic Blood Glucose Monitoring instrument of the cell phone application direct monitoring of the present invention, feature exist Include following functions module in the mobile phone APP terminal:User's registration logins module, blood glucose level data monitoring module, and event is defeated Enter module, data memory module, blood glucose level data sharing module, blood glucose level data statistical analysis module, nursing salvage service module;Institute The user's registration stated logins module for the management of the system user account and user data authorized agreement;The blood glucose level data Monitoring module is used to control the action of blood glucose transmitter, and receives the blood sugar concentration data of blood glucose transmitter transmission, aobvious in real time Show blood sugar concentration data;The event input module supports word input and speech recognition input, being capable of various dimensions record disease The life event of people provides medical information for diagnosis, and the life event includes motion exercise, medication, diet and rises Occupy information;The data memory module record blood sugar monitoring historical data and the life event, for understanding to blood glucose Horizontal favourable habits and customs;The blood glucose level data sharing module is stored blood glucose level data real time propelling movement by high in the clouds to family Member or medical staff realize the long-range monitoring to wearer's dynamic glucose;The blood glucose level data statistical analysis module is used for Count blood sugar history data, obtain blood sugar monitoring during change of blood sugar statistical law;The nursing salvage service mould Block is used to receive the tumble alert help signal of blood glucose transmitter transmission and low sugar stupor distress signal, is sent out to distal end APP terminals Send nursing alert help information.
A kind of improved technical solution of the Dynamic Blood Glucose Monitoring instrument of the cell phone application direct monitoring of the present invention, feature exist In the blood glucose sensor component and emitter assemblies using separable structure, all circuit portions of the emitter assemblies Part is packed using biocompatible materials, external contact V+, V-, S+, the S- for leaving connecting portion is packed, for connecting Blood glucose sensor component;The blood glucose sensor component is connected with emitter assemblies by connecting portion, is formed for dynamic blood The Wearable blood glucose transmitter of glucose monitor.
A kind of further improved technical solution of the Dynamic Blood Glucose Monitoring instrument of the cell phone application direct monitoring of the present invention, It is characterized in that the emitter assemblies further include battery charging module, lithium battery and power management module;The blood glucose passes The contact V '+and V ' of sensor component connecting portion-between be connected with switch element;When emitter assemblies and blood glucose sensor component it Between connecting portion when disconnecting, the contact V+ and V- of connecting portion forms the charging input end of emitter assemblies, can access charging voltage It is charged by battery charging module to lithium battery;Terminate to remove charging voltage and not connected blood glucose when emitter assemblies charge During sensor module, the lithium battery of emitter assemblies is connected to power management module power supply with being disconnected inside power management module Each circuit module of output terminal is in power failure state;When needing to carry out blood sugar monitoring, in the blood glucose sensor component The blood glucose sensor put is connected to emitter assemblies by the contact S+ and S- of connecting portion, and lithium battery passes through blood glucose sensor component Internal switch element is connected to power management module, and each circuit module of emitter assemblies powers on start-up operation.
A kind of preferred technical solution of the Dynamic Blood Glucose Monitoring circuit of the built-in acceleration sensor of the present invention, feature Be the switch element be connected to the contact V '+and V ' of the connecting portion-between touch switch, the switch element For negative logic pattern, blood glucose transmitter works on power when switch element disconnects;Blood glucose transmitter loses when the switching element is closed Electricity is stopped, and transmitter remains powered off state;It by the closure of the switch element and backs off, realizes to wireless SoC The power on reset operation of module.
It is a further object to provide a kind of Dynamic Blood Glucose Monitoring controls for above-mentioned Dynamic Blood Glucose Monitoring instrument Method, used technical solution are:
A kind of Dynamic Blood Glucose Monitoring control method for above-mentioned Dynamic Blood Glucose Monitoring instrument, it is characterised in that including following step Suddenly;
S100:The acquisition and pretreatment of dynamic glucose Concentration Testing data;
S200:The acquisition of human body attitude data and behavior act identification;
S300:The identification of hypoglycemic coma is saved oneself with wake-up and alert help;
S400:The wireless transmission of glucose monitor data.
A kind of preferable technical solution of the Dynamic Blood Glucose Monitoring control method of the present invention, it is characterised in that the step S100 includes following action:
S110:Blood glucose transmitter power-up initializing;
S120:Bluetooth BLE modules built in blood glucose transmitter establish data by bluetooth BLE modes and mobile phone APP terminal Communication connection;
S130:Start blood glucose sensor, current time, synchronous blood glucose sampling period are write to blood glucose transmitter;
S140:Blood glucose transmitter applies predetermined voltage drive to blood glucose sensor;
S150:Blood glucose sensor enters the polarization stand-by period;After the completion of polarization, mobile phone APP terminal writes reference blood glucose Enter to blood glucose sensor;
S160:Blood glucose transmitter starts to gather the current signal in blood glucose sensor, after sampled conditioning module conditioning, leads to It crosses ADC module sample conversion and is transmitted to wireless SoC modules into digital signal, calculate the blood glucose value for being converted to and representing blood sugar concentration;
S170:Blood glucose value is sent to mobile phone APP terminal by built-in bluetooth BLE modules by bluetooth approach.
A kind of superior technique scheme of the Dynamic Blood Glucose Monitoring control method of the present invention, it is characterised in that:
The step S200 includes following action:
S210:Blood glucose transmitter reads 3-axis acceleration by acceleration transducer and detects data;
S220:Data are detected according to 3-axis acceleration and carry out posture analysis and human action identification, by wearer's posture or Operating state is sent to mobile phone APP terminal;
S230:If recognition result is walking or running state, gathers and send wearer's exercise data to cell phone application end End, the exercise data include at least the step number of walking or running;
S240:If recognition result is wearer's tumble event, tumble alert help signal is sent by mobile phone APP terminal To distal end APP terminals;
The step S300 includes following action:
S310:If recognition result is stupor or sleep state, S320 is gone to step;Otherwise return to step S210;
S320:If blood sugar monitoring result is hypoglycemia, judge that wearer there are hypoglycemic coma risk, goes to step S330;Otherwise return to step S210;
S330:Alarm module is waken up by the motor built in blood glucose transmitter and starts the wake-up service of saving oneself;
S340:If wake-up is saved oneself effectively, return to step S210;Otherwise, low sugar stupor is sent by mobile phone APP terminal to ask Signal is rescued to distal end APP terminals.
A kind of improved technical solution of the Dynamic Blood Glucose Monitoring control method of the present invention, it is characterised in that the step S400 includes following action:
S410:Blood glucose transmitter judges connection status, if bluetooth connection is in connection status, goes to step S420 and otherwise returns Blood glucose transmitter and mobile phone APP terminal is waited to re-establish connection;Since blood glucose signal can not be sent to cell phone application in real time at this time Blood glucose value in acquisition is usually first stored temporarily in the flash memory module of SOC by terminal;
S420:Mobile phone APP terminal inquires about and reads historical data from flash memory module first;
S430:If historical data is all sent completely, into state is sent in real time, blood glucose transmitter will be most freshly harvested Glucose monitor data is sent to mobile phone APP terminal.
The beneficial effects of the invention are as follows:
1st, the Dynamic Blood Glucose Monitoring instrument and its control method of cell phone application direct monitoring of the invention, can be in continuous acquisition While with record blood sugar for human body, movement and the sleep info of wearer are obtained by 3-axis acceleration sensor, low blood is provided The identification of sugar stupor is saved oneself with wake-up, and glucose monitor data is sent to wireless receiving and dispatching by way of wireless transmission The intelligent handheld device of function or other external reception terminals display data analysis and remote-end alarm emergency service.
Motor is waken up and alarmed by the 2nd, the Dynamic Blood Glucose Monitoring instrument and its control method of cell phone application direct monitoring of the invention Module is placed in the emitter assemblies of blood glucose transmitter, is directly worn on human body;When detecting dangerous blood glucose signal, even if Departing from wireless receiver, it is appreciable that blood glucose transmitter still can directly send human body by motor wake-up alarm module Alarm improves the reliability for waking up self-rescue function.
3rd, the Dynamic Blood Glucose Monitoring instrument of cell phone application direct monitoring of the invention, blood glucose sensor component and emitter assemblies Using separable structure, disposable blood glucose sensor component and the repeatable emitter assemblies utilized are separated, emitted Device assembly is reusable after charging, and can greatly save cost, and glucose monitor data is transmitted to mobile phone by transmitting wirelessly APP terminals pass through mobile phone APP terminal software and realize blood Sugar Monitoring and statistical analysis, it is convenient to omit special blood glucose monitor terminal Cost, further mitigate patient medical burden.
Description of the drawings
Fig. 1 is for the circuit block diagram of the Wearable blood glucose transmitter of the Dynamic Blood Glucose Monitoring instrument of the present invention;
Fig. 2 is the structure diagram of the Dynamic Blood Glucose Monitoring instrument of the cell phone application direct monitoring of the present invention;
Fig. 3 is the cell phone application functional block diagram of the Dynamic Blood Glucose Monitoring instrument of cell phone application direct monitoring;
Fig. 4 is the control method flow chart of the Dynamic Blood Glucose Monitoring instrument of the cell phone application direct monitoring for the present invention;
Fig. 5 is dynamic glucose Concentration Testing data acquisition process flow chart;
Fig. 6 is human body attitude detection and Activity recognition and the control flow chart for waking up relief;
Fig. 7 is the flow chart of glucose monitor data wireless transmission;
Fig. 8 is the battery charging module of the Wearable blood glucose transmitter of the present invention;
Fig. 9 is the power management module of the Wearable blood glucose transmitter of the present invention;
Figure 10 is the blood glucose Acquisition Circuit of the Wearable blood glucose transmitter of the present invention;
Figure 11 is the ADC module of the Wearable blood glucose transmitter of the present invention;
Figure 12 is the acceleration sensor module of the Wearable blood glucose transmitter of the present invention;
Figure 13 is that the motor of the Wearable blood glucose transmitter of the present invention wakes up alarm module;
Figure 14 is the wireless SoC modules of the Wearable blood glucose transmitter of the present invention.
In figure, 100- blood glucose transmitters, 110- blood glucose sensor components, 120- emitter assemblies, 111- switch elements, 112- blood glucose sensors, 113- connecting portions, 121- sensor excitation modules, 122- sampling conditioning modules, 123- battery charging moulds Block, 124- lithium batteries, 125- power management modules, 126- flash memory modules, 127- motors wake-up alarm module, 128-ADC modules, SoC modules that 129- is wireless, 130- acceleration sensor modules, 200- mobile phone APP terminals, 210- user's registrations login module, 220- blood glucose level data monitoring modules, 230- event input modules, 240- data memory modules, 250- blood glucose level data sharing modules, 260- blood glucose level data statistical analysis modules, 270- nursing salvage service modules, the storage of 300- high in the clouds, 400- distal ends APP terminals.
Specific embodiment
For better understanding of the above-mentioned technical proposal of the present invention, carry out with reference to the accompanying drawings and examples further It is described in detail.
For the present invention Dynamic Blood Glucose Monitoring instrument Wearable blood glucose transmitter one embodiment as shown in Figure 1, The Wearable blood glucose transmitter is by the blood glucose sensor component 110 of built-in blood glucose sensor 112 and emitter assemblies 120 Connection composition.The blood glucose sensor component 110 and emitter assemblies 130 are using separable structure, the transmitter group All circuit blocks of part 120 are packed using biocompatible materials, pack the external contact for leaving connecting portion 113 V+, V-, S+, S-, for connecting blood glucose sensor component 110;The blood glucose sensor component 110 is right by connecting portion 113 The contact V ' answered+, V '-, S '+, S '-be connected to emitter assemblies 120, form the present invention cell phone application direct monitoring dynamic The Wearable blood glucose transmitter 100 of blood sugar monitoring instrument.The present invention is by being used as the blood glucose sensor group of disposable consumptive material Part 110 is separated with as repeatable using the emitter assemblies 120 of component, can be greatly saved client cost.V+ in Fig. 1, V-, S+, S- be 120 one side of emitter assemblies connecting portion 113 contact, V '+, V '-, S '+, S '-be connecting portion 113 and blood glucose The electrical contact that sensor module 110 is correspondingly connected with.
Embodiment according to figure 1, the emitter assemblies 120 include sensor excitation module 121, sampling conditioning Module 122, ADC module 128, wireless SoC modules 129, flash memory module 126;The emitter assemblies 120 further include acceleration Sensor assembly 130 and motor wake up alarm module 127.
The emitter assemblies 120 further include battery charging module 123, lithium battery 124 and power management module 125; The connecting portion contact V '+and V ' of the blood glucose sensor component 110-between be connected with switch element 111;Work as emitter assemblies When connecting portion 113 between 120 and blood glucose sensor component 110 disconnects, the electrical contact V+ and V- of connecting portion 113 are formed The charging input end of emitter assemblies 120 can access 5V charging voltages, pass through the battery charging module 123 of emitter assemblies 120 It charges to lithium battery 124;
After 124 charging complete of lithium battery of emitter assemblies 120, remove 5V charging voltages, emitter assemblies 120 due to It is not connected with blood glucose sensor component 110, lithium battery 124 and 125 inside of power management module disconnect, and are connected to power management Each circuit module of the power supply output terminal of module 125 is in power failure state.This connection mode of emitter assemblies 120 can be real Existing emitter assemblies 120 automatically power off, and so as to extend the stand-by time of emitter assemblies 120, extend 100 product of blood glucose transmitter Stock's shelf cycle;
When needing to carry out blood sugar monitoring, the blood glucose sensor component 110 of blood glucose transmitter 100 is implanted into human body, blood glucose Sensor module 110 is connected to by connecting portion 113 in emitter assemblies 120, and lithium battery 124 passes through blood glucose sensor component Switch element 111 inside 110 is connected to power management module 125, and each circuit module of emitter assemblies 120 powers on beginning work Make.
One embodiment of blood glucose sensor component 110 according to the present invention, the switch element 111 is is connected to State the contact V '+and V ' of connecting portion 113-between PCB short-circuit lines.
Another embodiment of blood glucose sensor component 110 according to the present invention, the switch element 111 are to be connected to The contact V '+and V ' of the connecting portion 113-between contact-making switch, the switch element 111 is operated in negative logic pattern:When When switch element 111 disconnects, blood glucose transmitter 100 works on power;When the switching element is closed, blood glucose emits 100 dead electricity and stops Work, emitter assemblies 110 remain powered off state;It by the closure of the switch element 111 and backs off, can realize pair The power on reset operation of wireless SoC modules 129.In the present embodiment, the emitter assemblies 120 set short-circuit line equipped with interior Contact protection lid, when the connecting portion 113 of the contact protection lid closing emitter assemblies 120, the short-circuit line will touch Point V+ and V- short circuits, make emitter assemblies 120 remain powered off state, so as to extend the stand-by time of emitter assemblies 120, extend Stock's shelf cycle of 100 product of blood glucose transmitter.
The wireless SoC modules 129 send instructions to sensor excitation module 121, it are made to apply sensor suitable Voltage, the blood glucose sensor 112 in blood glucose sensor component 110 starts to work, and blood glucose sensor 112 generates faint electric current Signal, this current signal reflect human body level.
The sampled conditioning module 122 of current signal that blood glucose sensor 112 generates is converted into voltage signal, filtered, send To 128 circuit analog-to-digital conversion of ADC module, it is converted into digital signal and sends the wireless SoC modules 129 of governor circuit to, pass through fortune Calculate and calculate human blood glucose concentration value, be stored in flash memory module 126 or cell phone application is sent to by wireless connection in real time Terminal 200.
One embodiment of the battery charging module 123 is as shown in figure 8, be rechargeable lithium battery between wherein J1 and J2 124.U1 is charging management chip, preferably BQ24041, selects the resistance value setting battery charging rated current of resistance R18.Selection electricity The resistance value setting battery charge cutoff electric current of R21 is hindered, selects R22 that the maximum current amplitude limit to charge is set.R23 pull down resistors, make It can charging chip./ SHDN signals open shut-off for electric power management circuit, and specific logic is to work as V+, during V- short circuits ,/SHDN Low level, turning off system power supply are pulled down to by R4 and D1;Charge power supply meets V+, during V- or hanging ,/SHDN outputs by R1 and R4 is pulled to high voltage, and signal is sent to electric power management circuit, open system power supply.When in charging, CHG_PG output signals are Height, CHG output signals are low.CHG exports high level when charging is complete;When CHG_PG is high, expression does not access charge power supply. Pass through CHG_PG signals and CHG signal state, it can be determined that the working condition and charged state of transmitter, these states are sent to SOC computings, it is then bright by the breath light progress connected on SOC, it goes out, flickers to indicate corresponding state.
One embodiment of the power management module 125 is as shown in Figure 9:The rated output voltage of lithium battery 124 is 3.7V or so, but the power supply of wireless SOC and the power supply of amplifier are 3V, and the reference voltage of transducer excitation voltage For 1.25V.So the effect of power management module 125 is by power supply chip U2 (preferably UM1560DB) that 3.7V lithium batteries is defeated Go out and be depressured to 3V, and accurately 1.25V reference voltages are given for utilization Precision reference power supply chip U3 (preferably REF3312) generations one Sensor excitation circuit.Due to circuit, there are analog portions and numerical portion.In order to improve sampling precision and Immunity Performance, power supply The PCB of management module 125 is using the measure of simulation ground/power supply and digitally/isolated from power, and using inductance L1, L2, L3 are isolation Numerical portion and analog portion afterwards connects, and C2, C3, C4, C5 are power filtering capacitor.
According to embodiment shown in Fig. 10, the blood glucose Acquisition Circuit of Wearable blood glucose transmitter of the invention includes sensing Device encourages module 121 and sampling conditioning module 122:Blood glucose sensor 112 is worked based on electrochemical principle, normal work When, it is necessary to apply the voltage drive of different stalls to sensor positive electrode S+, wherein, Q2, R10, R12 composition voltage gear selections Circuit.The gate pole V_SEL of Q2 is connected to the I/O pin of SoC chip, and voltage gear is selected by microcontroller.When Q2 is turned on, R10 does not join Add operational amplifier circuit computing, generate voltage V1 to sensor anode S+.When Q2 is not turned on, R10 will participate in operational amplifier circuit computing, S+ meetings Generate voltage V2 to sensor anode S+.If also needing to the voltage of more grades, the selection of voltage order one gear can be further added by Circuit.:The signal that blood glucose sensor 112 exports be current signal, it is necessary to sampled conditioning module 122 is handled, could generate directly It connects for the input voltage signal of ADC module 128.It is nA ranks since the current level of blood glucose sensor 112 is very faint, because This nurses one's health signal using current/voltage operational amplifier circuit.R5 is feedback resistance in figure, and C7 is feedback capacity, and C7 is used to support The influence for the input capacitance that disappears improves the response time, while regular hour constant is also provided together with R5.U4 should select low biasing The accurate amplifier of electric current, the preferred 1M~2M Europe precision resistances of U4 preferred TSV712, wherein R5, it is contemplated that band needed for sensor signal Not high, the preferred 10nF~100nF of C7 of width.Into after voltage signal, output ADC_GLU is connected to the conditioned circuit conversion of current signal Adc circuit carries out analog-to-digital conversion.According to the short principle of void of amplifier, the Pin5 of amplifier connects 1.25V voltages, is equivalent to sensor cathode S- is connected on reference potential 1.25V.
One embodiment of the ADC module 128 is as shown in figure 11:In order to improve AD sampling precisions, the present embodiment uses A piece of dedicated Differential Input high resolution A/D C conversion chips, preferably ADS1220, the output ADC_GLU of over-sampling modulate circuit and The reference voltage 1.25V of sensor cathode S- can effectively reduce sampling noise as two Differential Inputs of ADC, this mode, Improve the reliability of sampled result.The result of ADS1220 is output to SOC governor circuits by way of SPI and carries out computing.R14, R16, C22, C27, C28 form signal filter circuit, can effectively filter out the common mode and differential mode noise of sampled signal.C20 and C21 are Power filtering capacitor.According to another embodiment of the invention, the ADC module 128 is using built in wireless SoC modules 129 ADC function modules.
The acceleration sensor module 130 is connected to wireless SoC modules 129, and wireless SoC modules 129 pass through acceleration It spends sensor assembly 130 and detects three-dimensional acceleration signal, the steric acceleration data of 100 wearer of acquisition blood glucose transmitter, warp Attitude measurement feature and movement statistics feature are extracted in data processing, obtain movement and the sleep info of human body;By being based on posture The tumble for measuring feature judges, before and after human body, it is lateral fall and stand rapidly after falling in the case of, can send and fall in time The signal of falling alert help, and relevant information is recorded in flash memory module 126 or is sent to mobile phone APP terminal 200 in real time. In view of influence of noise and fall detection algorithm to the high request of detection accuracy, can also be carried using Kalman filter algorithm High algorithm accuracy.
One embodiment of acceleration sensor module 130 is as shown in figure 12:It is sensed in this example using 3-axis acceleration Device U7 can be transported as acceleration test components, preferably model LSH3DH, 3-axis acceleration sensor not knowing object in advance Under the occasion in dynamic direction, by detecting the steric acceleration of three-dimensional acceleration signal measurement object, so as to accurately reflect object comprehensively The kinetic property of body, for example, extracting attitude measurement feature and movement system by the processing of the steric acceleration data to collecting Feature is counted, including standard deviation, threshold value, the degree of bias, kurtosis etc., calculates standing, seat, prone position state and walking, race, the jump of identification wearer Action obtains movement and the sleep info of human body.The data communication interface of acceleration transducer and wireless SOC circuits supports SPI Or I2C interface, the present embodiment selection SPI interface, because the rate of SPI is far above I2C.C29 and C30 is power filter electricity Hold.
The embodiment of the Wearable blood glucose transmitter of the present invention according to figure 1, the emitter assemblies 120 are also wrapped It includes motor and wakes up alarm module 127;The motor wakes up alarm module 127 and is connected to wireless SoC modules 129, when discovery is worn There are during hypoglycemic coma risk, the Wearable blood glucose transmitter wakes up alarm module 127 by motor and starts wearer Wake-up is saved oneself, and low sugar stupor distress signal is sent by external reception terminal.
One embodiment that the motor wakes up alarm module 127 is as shown in figure 13:The pull down resistor of metal-oxide-semiconductor input terminal R26 is for ensureing restarting momentary motor remains stationary, because pin is high level to chip after the power is turned on, MOS is in the conduction state, So that there are of short duration vibrations for motor.M+, M- connect eccentric vibrating motor.Pin Motor is connected to wireless SoC modules 129 Corresponding pin.D3 is fly-wheel diode when motor Q3 is disconnected.
It is extremely dangerous that at night hypoglycemia, which occurs, for diabetic.After especially patient sleep soundly, caused by hypoglycemia Hypoglycemic coma cannot find that patient is powerless to save oneself or cry for help to others, and may be delayed rescue opportunity can even endanger in time And life.Warning circuit is usually placed in wireless receiver by the existing blood glucose meter with warning function, but due to wirelessly connecing The connection received between device and blood glucose transmitter may disconnect, even if blood glucose transmitter detects dangerous blood glucose signal at this time, the blood Sugared data can be because connection, which disconnects, cannot be timely transmitted to wireless receiver;Wireless receiver not can know that patient is currently at In dangerous blood sugar condition, thus alarm cannot be sent.The Wearable blood glucose transmitter of the present invention, alarm module is waken up by motor 127 are placed in the emitter assemblies 120 of blood glucose transmitter 100, are directly worn on human body;When detecting dangerous blood glucose signal When, even if departing from wireless receiver, blood glucose transmitter 100 still can wake up alarm module 127 by motor and directly send The appreciable alarm of human body.
Technical scheme takes gradual wake-up mode according to sleep state, can greatly improve user experience, Patient is avoided because existing warning function often wakes up directly by it from sleep generates unhealthy emotion, and then it is low to close night Blood glucose warning function and generate potential risk.
Embodiment according to Figure 14, the wireless SoC modules 129 are integrated with microprocessor cotex-M0 and bluetooth Low energy consumption module (bluetooth BLE modules).Y2, C12, C14 composition low-frequency clock source, Y1, C10, C11 composition high frequency clocks source. Pin19~Pin23 is the data communication interface of SOC and adc circuit, and Pin8~Pin11, Pin25, Pin26 is SOC and acceleration The data communication interface of sensor assembly 130.Pin4 selects for the voltage gear of sensor excitation module 121.It is gone here and there on Pin5 R17 and D2 have been met, as the breath light of whole system, has realized the instruction of 100 simple state of blood glucose transmitter.Pin6, Pin7 are The detection of battery status can detect that battery is in charging, charges and does not completely still access the states such as charge power supply.TP1~TP4 For program burn writing and emulation input port.L4, L5, L6, C17, C18, C19, C26 are balun circuit, while play antenna impedance With effect.E1 is antenna.R13 and R15 is connected to the AD pin Pin48 of SOC by partial pressure, for the detection of battery capacity.
Although the wireless transmit/receive units in the present embodiment built in wireless SoC modules are preferably bluetooth BLE modules, in fact, Wireless transmit/receive units can also be using zigbee, wifi or based on the ISM433/868/915Mhz frequency ranges for exempting to license Communication;The near-field communication modes that NFC/RFID can also be used similar.
Technical scheme can also utilize acceleration sensor module 130 to provide step function and derivative energy Function is consumed, and is applied it in glycemic control.For example, being counted for a period of time to certain, this section of time disease is counted The step number and energy expenditure number of people excavates the step number of patient itself and the rule of change of blood sugar amount to the relation of change of blood sugar amount Rule.If current blood glucose is higher, patient, which knows, needs how many step number that could blood glucose be dropped to safe range.
Fig. 2 is one embodiment of the Dynamic Blood Glucose Monitoring instrument of the cell phone application direct monitoring of the present invention, can be worn including one Belt blood glucose transmitter 100, as Dynamic Blood Glucose Monitoring exterior terminal at least one mobile phone APP terminal 200 and pass through hand The high in the clouds storage 300 that machine APP terminals 200 connect;
The blood glucose transmitter 100 is as shown in Figure 1,110 He of blood glucose sensor component by built-in blood glucose sensor 112 The connection composition of emitter assemblies 120;The emitter assemblies 120 include sensor excitation module 121, sample conditioning module 122, ADC module 128, wireless SoC modules 129 and acceleration sensor module 130 and motor wake up alarm module 127;Institute The sensor excitation module 121 stated applies driving voltage to blood glucose sensor 112;The sampling conditioning module 122 is by blood Sugared sensor 112 current signal conditioning into 128 matched voltage signal of ADC module;ADC module 128 is by the electricity after conditioning Pressure signal is converted into being sent to after digital signal the main control chip of the wireless SoC modules 129 of transmitter, and main control chip is according to sample conversion Digital signal calculate blood sugar concentration, cell phone application is sent to by the bluetooth BLE modules being integrated in wireless SoC modules 129 Terminal 200;The acceleration sensor module 130 is connected to wireless SoC modules 129, obtains the movement of human body and sleep letter Breath, realizes that the identification of hypoglycemic coma and wake-up are saved oneself and alert help function;
The mobile phone APP terminal 200 is connected to blood glucose transmitter 100 by bluetooth mode, realizes the dynamic of blood sugar concentration State monitors;The mobile phone APP terminal 200 is connected to high in the clouds storage 300 by mobile communication network;
Described high in the clouds storage 300 is used for storing the blood glucose level datas of blood glucose transmitter acquisition, and by authorized user The network share of glucose monitor data is realized in push.
According to the embodiment of the Dynamic Blood Glucose Monitoring instrument of the cell phone application direct monitoring of the present invention shown in Fig. 2, work is further included For at least one distal end APP terminals 400 of Dynamic Blood Glucose Monitoring exterior terminal;The distal end APP terminals 400 include at least blood Sugared data monitoring module, blood glucose level data statistical analysis module and nursing relief alarm module;When mobile phone APP terminal 200 licenses to After distal end APP terminals 400, distal end APP terminals 400 receive the number that blood glucose transmitter 100 is uploaded by mobile phone APP terminal 200 According to the strange land monitoring and statistical analysis of realization blood glucose transmitter;The nursing relief alarm module receives mobile phone APP terminal The 200 nursing relief warning messages sent realize the distal end nursing relief alert service of hypoglycemic coma.The distal end APP Terminal 400 includes the kinsfolk of wearer or mobile phone, tablet computer or the desktop computer of medical staff.
One implementation of the Dynamic Blood Glucose Monitoring instrument of cell phone application direct monitoring according to the present invention, as shown in figure 3, described Mobile phone APP terminal 200 include following functions module:User's registration logins module 210, blood glucose level data monitoring module 220, event Input module 230, data memory module 240, blood glucose level data sharing module 250, blood glucose level data statistical analysis module 260, nursing Salvage service module 270;
The user's registration logins module 210 for the management of the system user account and user data authorized agreement; The blood glucose level data monitoring module 220 is used to control the action of blood glucose transmitter 100, and receives blood glucose transmitter 100 and send out The blood sugar concentration data sent, real-time display blood sugar concentration data;
The event input module 230 supports word input and speech recognition input, is capable of various dimensions record patient's Life event provides medical information for diagnosis, and the life event includes motion exercise, medication, diet and daily life letter Breath;
The data memory module 240 records blood sugar monitoring historical data and the life event, for understanding pair The favourable habits and customs of blood glucose level;
The blood glucose level data sharing module 250 is by high in the clouds storage 300 by blood glucose level data real time propelling movement to kinsfolk Or medical staff, realize the long-range monitoring to wearer's dynamic glucose;
The blood glucose level data statistical analysis module 260 is for counting blood sugar history data, during obtaining blood sugar monitoring Change of blood sugar statistical law;
The nursing salvage service module 270 is used to receive the tumble alert help signal of the transmission of blood glucose transmitter 100 With low sugar stupor distress signal, nursing alert help information is sent to distal end APP terminals 400.
Fig. 4 be for the flow chart of the control method of the Dynamic Blood Glucose Monitoring instrument of above-mentioned cell phone application direct monitoring, including with Lower step;
S100:The acquisition and pretreatment of dynamic glucose Concentration Testing data;
S200:The acquisition of human body attitude data and behavior act identification;
S300:The identification of hypoglycemic coma is saved oneself with wake-up and alert help;
S400:The wireless transmission of glucose monitor data.
Dynamic glucose Concentration Testing data acquisition process flow chart according to Fig. 5, the step S100 include with Lower action:
S110:Blood glucose transmitter power-up initializing;
S120:Bluetooth BLE modules built in blood glucose transmitter establish data by bluetooth BLE modes and mobile phone APP terminal Communication connection;
S130:Start blood glucose sensor, current time, synchronous blood glucose sampling period are write to blood glucose transmitter;
S140:Blood glucose transmitter applies predetermined voltage drive to blood glucose sensor;
S150:Blood glucose sensor enters the polarization stand-by period;After the completion of polarization, mobile phone APP terminal 200 is by reference blood glucose It is written to blood glucose sensor;
S160:Blood glucose transmitter starts to gather the current signal in blood glucose sensor, after sampled conditioning module conditioning, leads to It crosses ADC module sample conversion and is transmitted to wireless SoC modules into digital signal, calculate the blood glucose value for being converted to and representing blood sugar concentration;
S170:Blood glucose value is sent to mobile phone APP terminal by built-in bluetooth BLE modules by bluetooth approach.
The embodiment of the control method of Dynamic Blood Glucose Monitoring instrument according to Fig. 6, the step S200 include following Action:
S210:Blood glucose transmitter reads 3-axis acceleration by acceleration transducer and detects data;
S220:Data are detected according to 3-axis acceleration and carry out posture analysis and human action identification, by wearer's posture or Operating state is sent to mobile phone APP terminal;
S230:If recognition result is walking or running state, gathers and send wearer's exercise data to cell phone application end End, the exercise data include at least the step number of walking or running;
S240:If recognition result is wearer's tumble event, tumble alert help signal is sent by mobile phone APP terminal To distal end APP terminals;
The step S300 includes following action:
S310:If recognition result is stupor or sleep state, S320 is gone to step;Otherwise return to step S210;
S320:If blood sugar monitoring result is hypoglycemia, judge that wearer there are hypoglycemic coma risk, goes to step S330;Otherwise return to step S210;
S330:Alarm module is waken up by the motor built in blood glucose transmitter and starts the wake-up service of saving oneself;
S340:If wake-up is saved oneself effectively, return to step S210;Otherwise, low sugar stupor is sent by mobile phone APP terminal to ask Signal is rescued to distal end APP terminals.
According to embodiment shown in Fig. 7, the wireless transmission of glucose monitor data uses bluetooth mode.Since Bluetooth signal subtracts The reason for weak loss or software requirement, in euglycemia gatherer process, the Bluetooth transmission module built in blood glucose transmitter 100 Connection status or off-state are likely to be at mobile phone APP terminal 200.Therefore, glucose monitor data is sent by two ways To mobile phone APP terminal 200.The step S400 includes following action:
S410:Blood glucose transmitter judges connection status, if bluetooth connection is in connection status, goes to step S420 and otherwise returns Blood glucose transmitter 100 and mobile phone APP terminal 200 is waited to re-establish connection;Since blood glucose signal can not be sent in real time at this time Blood glucose value in acquisition is usually first stored temporarily in the flash memory module 126 of SOC by mobile phone APP terminal 200;
S420:Mobile phone APP terminal inquires about and reads historical data from flash memory module 126 first;
S430:If historical data is all sent completely, into state is sent in real time, blood glucose transmitter 100 is adopted newest The glucose monitor data of collection is sent to mobile phone APP terminal.
After mobile phone APP terminal 200 receives the blood glucose concentration value of transmitter, real-time display is on mobile phone, while data are sent out It is sent to high in the clouds storage 300.After blood glucose concentration value samples certain amount, APP user can select the side with precession diagram Formula is shown so Historical Monitoring value.
When life event occurs for user, user can directly use word input or voice mode by the life thing Part typing mobile phone APP terminal 200, the life event include diet, take exercise, the medication life thing related with blood glucose level Part.Mobile phone APP terminal 200 can on the basis of the time point of event typing, before and after display event 3~5 it is small when blood glucose collection of illustrative plates, For judging influence of the life event to blood sugar concentration.And each corresponding continuous blood sugar collection of illustrative plates of life event can be folded Add, to compare observation.
After the completion of monitoring, mobile phone APP terminal 200 sends the order for terminating monitoring, blood glucose transmitter to blood glucose transmitter 100 100 are stopped, and blood glucose transmitter 100 from human body can be removed or disconnected emitter assemblies 120 and be passed with blood glucose by user Connecting portion 113 between sensor component 110, emitter assemblies 120 are removed from human body, terminate entire blood sugar monitoring process.
Those of ordinary skill in the art it should be appreciated that more than embodiment be intended merely to illustrate the present invention's Technical solution, and be not used as limitation of the invention, any connotation based on the present invention is to embodiment described above Variation, the modification made will all fall in the scope of the claims of the present invention.

Claims (10)

1. a kind of Dynamic Blood Glucose Monitoring instrument of cell phone application direct monitoring, including a Wearable blood glucose transmitter, as dynamic At least one mobile phone APP terminal of blood sugar monitoring exterior terminal and the high in the clouds connected by mobile phone APP terminal store, special Sign is:
The blood glucose transmitter is connected with emitter assemblies by the blood glucose sensor component of built-in blood glucose sensor and formed;It is described Emitter assemblies include sensor excitation module, sample conditioning module, ADC module, wireless SoC modules and acceleration pass Sensor module and motor wake up alarm module;The sensor excitation module applies driving voltage to blood glucose sensor;Institute The sampling conditioning module stated by the conditioning of the current signal of blood glucose sensor into the matched voltage signal of ADC module;ADC module will Voltage signal after conditioning is converted into being sent to after digital signal the main control chip of the wireless SoC modules of transmitter, main control chip according to The digital signal of sample conversion calculates blood sugar concentration, in one's hands by being integrated in the bluetooth BLE modules transmission in the block of wireless SoC moulds Machine APP terminals;The acceleration sensor module is connected to wireless SoC modules, obtains movement and the sleep info of human body, real The identification and wake-up of existing hypoglycemic coma are saved oneself and alert help function;
The mobile phone APP terminal is connected to blood glucose transmitter by bluetooth mode, realizes the dynamic monitoring of blood sugar concentration;
The mobile phone APP terminal is connected to high in the clouds by mobile communication network and stores;
The high in the clouds storage is used for storing the blood glucose level data of blood glucose transmitter acquisition, and is realized by being pushed to authorized user The network share of glucose monitor data.
2. the Dynamic Blood Glucose Monitoring instrument of cell phone application direct monitoring according to claim 1, it is characterised in that further include conduct At least one distal end APP terminals of Dynamic Blood Glucose Monitoring exterior terminal;The distal end APP terminals are supervised including at least blood glucose level data Control module, blood glucose level data statistical analysis module and nursing relief alarm module;When mobile phone APP terminal licenses to distal end APP terminals Afterwards, APP terminals in distal end receive the data that blood glucose transmitter is uploaded by mobile phone APP terminal, realize the strange land of blood glucose transmitter Monitoring and statistical analysis;The nursing relief alarm module receives the nursing relief warning message that mobile phone APP terminal is sent, real The distal end nursing relief alert service of existing hypoglycemic coma.
3. the Dynamic Blood Glucose Monitoring instrument of cell phone application direct monitoring according to claim 1, it is characterised in that it is characterized in that The mobile phone APP terminal includes following functions module:User's registration logins module, blood glucose level data monitoring module, event input Module, data memory module, blood glucose level data sharing module, blood glucose level data statistical analysis module nurse salvage service module;It is described User's registration login module for the management of the system user account and user data authorized agreement;The blood glucose level data prison Control module is used to control the action of blood glucose transmitter, and receives the blood sugar concentration data of blood glucose transmitter transmission, real-time display Blood sugar concentration data;The event input module supports word input and speech recognition input, being capable of various dimensions record patient Life event, provide medical information for diagnosis, the life event includes motion exercise, medication, diet and daily life Information;The data memory module record blood sugar monitoring historical data and the life event, for understanding to blood glucose water Flat favourable habits and customs;The blood glucose level data sharing module by high in the clouds store by blood glucose level data real time propelling movement to family into Member or medical staff, realize the long-range monitoring to wearer's dynamic glucose;The blood glucose level data statistical analysis module is used to unite Count blood sugar history data, obtain blood sugar monitoring during change of blood sugar statistical law;The nursing salvage service module For receiving the tumble alert help signal of blood glucose transmitter transmission and low sugar stupor distress signal, sent to distal end APP terminals Nurse alert help information.
4. the Dynamic Blood Glucose Monitoring instrument of cell phone application direct monitoring according to claim 1, it is characterised in that the blood glucose Using separable structure, all circuit blocks of the emitter assemblies use biofacies for sensor module and emitter assemblies Capacitive material packs, and external contact V+, V-, S+, the S- for leaving connecting portion is packed, for connecting blood glucose sensor group Part;The blood glucose sensor component is connected with emitter assemblies by connecting portion, forms wearing for Dynamic Blood Glucose Monitoring Belt blood glucose transmitter.
5. the Dynamic Blood Glucose Monitoring instrument of cell phone application direct monitoring according to claim 4, it is characterised in that the transmitting Device assembly further includes battery charging module, lithium battery and power management module;The blood glucose sensor component connecting portion touches Point V '+and V '-between be connected with switch element;When the connecting portion between emitter assemblies and blood glucose sensor component disconnects, The contact V+ and V- of connecting portion form the charging input end of emitter assemblies, can access charging voltage and pass through battery charging module pair Lithium battery charges;Terminate to remove charging voltage and during not connected blood glucose sensor component when emitter assemblies charge, transmitting The lithium battery of device assembly is connected to each circuit module of power management module power supply output terminal with being disconnected inside power management module It is in power failure state;When needing to carry out blood sugar monitoring, the blood glucose sensor built in the blood glucose sensor component passes through The contact S+ and S- of connecting portion are connected to emitter assemblies, and lithium battery is connected by the switch element of blood glucose sensor component internal To power management module, each circuit module of emitter assemblies powers on start-up operation.
6. the Dynamic Blood Glucose Monitoring instrument of cell phone application direct monitoring according to claim 5, it is characterised in that it is characterized in that The switch element be connected to the contact V '+and V ' of the connecting portion-between touch switch, the switch element is negative Logical schema, blood glucose transmitter works on power when switch element disconnects;Blood glucose transmitter dead electricity is stopped when the switching element is closed It only works, transmitter remains powered off state;It by the closure of the switch element and backs off, realizes to wireless SoC modules Power on reset operation.
7. a kind of Dynamic Blood Glucose Monitoring control of the Dynamic Blood Glucose Monitoring instrument described in any claim for claim 1 to 6 Method processed, it is characterised in that comprise the following steps:
S100:The acquisition and pretreatment of dynamic glucose Concentration Testing data;
S200:The acquisition of human body attitude data and behavior act identification;
S300:The identification of hypoglycemic coma is saved oneself with wake-up and alert help;
S400:The wireless transmission of glucose monitor data.
8. Dynamic Blood Glucose Monitoring control method according to claim 7, it is characterised in that the step S100 include with Lower action:
S110:Blood glucose transmitter power-up initializing;
S120:Bluetooth BLE modules built in blood glucose transmitter establish data communication by bluetooth BLE modes and mobile phone APP terminal Connection;
S130:Start blood glucose sensor, current time, synchronous blood glucose sampling period are write to blood glucose transmitter;
S140:Blood glucose transmitter applies predetermined voltage drive to blood glucose sensor;
S150:Blood glucose sensor enters the polarization stand-by period;After the completion of polarization, reference blood glucose is written to by mobile phone APP terminal Blood glucose sensor;
S160:Blood glucose transmitter starts to gather the current signal in blood glucose sensor, after sampled conditioning module conditioning, passes through ADC module sample conversion is transmitted to wireless SoC modules into digital signal, calculates the blood glucose value for being converted to and representing blood sugar concentration;
S170:Blood glucose value is sent to mobile phone APP terminal by built-in bluetooth BLE modules by bluetooth approach.
9. Dynamic Blood Glucose Monitoring control method according to claim 7, it is characterised in that:
The step S200 includes following action:
S210:Blood glucose transmitter reads 3-axis acceleration by acceleration transducer and detects data;
S220:Data are detected according to 3-axis acceleration and carry out posture analysis and human action identification, by wearer's posture or action State is sent to mobile phone APP terminal;
S230:If recognition result is walking or running state, gathers and send wearer's exercise data to mobile phone APP terminal, The exercise data includes at least the step number of walking or running;
S240:If recognition result is wearer's tumble event, tumble alert help signal is sent to far by mobile phone APP terminal Hold APP terminals;
The step S300 includes following action:
S310:If recognition result is stupor or sleep state, S320 is gone to step;Otherwise return to step S210;
S320:If blood sugar monitoring result is hypoglycemia, judge that wearer there are hypoglycemic coma risk, goes to step S330;It is no Then return to step S210;
S330:Alarm module is waken up by the motor built in blood glucose transmitter and starts the wake-up service of saving oneself;
S340:If wake-up is saved oneself effectively, return to step S210;Otherwise, low sugar stupor emergency letter is sent by mobile phone APP terminal Number to distal end APP terminals.
10. Dynamic Blood Glucose Monitoring control method according to claim 7, it is characterised in that the step S400 include with Lower action:
S410:Blood glucose transmitter judges connection status, if bluetooth connection is in connection status, goes to step S420 and otherwise returns to waiting for Blood glucose transmitter and mobile phone APP terminal re-establish connection;Since blood glucose signal can not be sent to cell phone application end in real time at this time Blood glucose value in acquisition, is usually first stored temporarily in the flash memory module of SOC by end;
S420:Mobile phone APP terminal inquires about and reads historical data from flash memory module first;
S430:If historical data is all sent completely, into state is sent in real time, blood glucose transmitter will most freshly harvested blood glucose Monitoring data are sent to mobile phone APP terminal.
CN201611022085.9A 2016-11-21 2016-11-21 The Dynamic Blood Glucose Monitoring instrument and its control method of a kind of cell phone application direct monitoring Pending CN108078569A (en)

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