CN107966582A - A kind of sample collection detector - Google Patents
A kind of sample collection detector Download PDFInfo
- Publication number
- CN107966582A CN107966582A CN201711106194.3A CN201711106194A CN107966582A CN 107966582 A CN107966582 A CN 107966582A CN 201711106194 A CN201711106194 A CN 201711106194A CN 107966582 A CN107966582 A CN 107966582A
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- sample
- chamber
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- sampling
- valve
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1009—Characterised by arrangements for controlling the aspiration or dispense of liquids
- G01N35/1016—Control of the volume dispensed or introduced
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N2035/1027—General features of the devices
- G01N2035/103—General features of the devices using disposable tips
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- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Sampling And Sample Adjustment (AREA)
Abstract
A kind of sample collection detector, has sampling mechanism, testing agency and means of communication, and sampling mechanism has sampling cavity and sample transfer bar, and sample transfer bar insertion sampling cavity completes sampling；Means of communication has connection sampling cavity and the sample presentation passage of testing agency, there is valve module between sample presentation passage and sampling cavity, is closed when valve module is initial, sample presentation passage is isolated with sampling cavity, the unlatching of sample transfer bar triggering valve module, connection sample presentation passage and sampling cavity.The present invention has the advantages that quantitatively sample can be chosen and take into account detection efficiency and operation healthy requirement.
Description
Technical field
The present invention relates to biological monitoring technical field, and in particular to a kind of sample collection detector.
Background technology
In field of medical biotechnology, the analysis of sample is detected through in whole process, and the analysis detection of sample is numerous examinations
The basis tested and treated.But there is the problem of detection is inconvenient in current sample monitor in detection process.The inspection of sample
Survey need with detection liquid reacted, and sample with detection liquid mixed process due to cumbersome, it is large batch of or requirement
In the case of detection efficiency, limitation is just shown, be inconvenient in addition, for some samples with pollution property itself
What operating personnel were directly contacted, detection for such sample is, it is necessary to which that takes into account detection efficiency and safe operation health will
Ask.And current sample detector quantitatively cannot be chosen sample, easily to be mixed with detection liquid to be detected.
The content of the invention
Quantitatively sample can be chosen it is an object of the invention to provide one kind and take into account detection efficiency and operation
The sample collection detector of healthy requirement.
A kind of sample collection detector, has sampling mechanism, testing agency and means of communication, and sampling mechanism has sampling cavity
And sample transfer bar, sample transfer bar insertion sampling cavity complete sampling；Means of communication has connection sampling cavity and the sample presentation passage of testing agency,
There is valve module between sample presentation passage and sampling cavity, closed when valve module is initial, sample presentation passage is isolated with sampling cavity, sample transfer bar triggering
Valve module is opened, connects sample presentation passage and sampling cavity.
Further, valve module has valve chamber, push rod and closure member, valve chamber connection sampling cavity and sample presentation passage, closure member
Seal the outlet of valve chamber；Means of communication has the space for providing push rod insertion.
The concrete structure of push rod is：Push rod has carrier, sealing and the bottom for crossing sample portion, carrier and sample transfer bar
End matches, and when sample transfer bar triggering valve module is opened, crosses the outlet that sample portion makes closure member open valve chamber, after quantitative sample presentation, sealing
The outlet of closeding valve cavity.
Sealing position is between carrier and excessively sample portion, the outlet interference fit of sealing and valve chamber, crosses the appearance in sample portion
Face is provided with axial sample groove excessively；Alternatively, crossing sample portion and valve chamber has gap.Cross sample groove or the gap shape excessively between sample portion and valve chamber
Into runner, sample mixed liquor enters means of communication through runner.By the length, the excessively size of sample groove or the mistake sample portion that set sample portion
The size in the gap between valve chamber, realizes the quantitative conveying to liquid sample.
Carrier is piston, and piston has outwardly extending dish-shaped fin, and dish-shaped fin is flexible piece.Butterfly fin is pressed into
The deformation during entrance of valve chamber, the entrance of closeding valve cavity, piston realize the dual-seal to valve chamber with sealing.
Further, the concrete structure of closure member is：Closure member includes the plug for independently clogging valve chamber.In use, use sample presentation
Bar triggers push rod, and the sample portion of crossing of push rod pushes away plug from valve chamber, and liquid sample enters testing agency by crossing sample portion.
Alternatively, closure member includes the plug in push rod.Sample portion is crossed between sealing and plug.In use,
Push rod is triggered with sample transfer bar, when plug leaves valve chamber outlet, sample portion is crossed and reaches valve chamber outlet, liquid sample is entered by crossing sample portion
Testing agency, push rod continue to run with, and sealing closeding valve cavity outlet, sample presentation is completed.
To improve the reliability of closure member, closure member further includes the Obstruct membrane for being arranged at valve chamber outlet.Including plug, barrier
Outside, double-layer seal isolates sampling cavity and testing agency to film.Referred to inside and outside herein with respect to inside and outside for valve chamber.Push rod
During operation, plug breaks Obstruct membrane completely, avoid Obstruct membrane completely enclose or partially enclosed sample presentation passage and cause sample to determine
The problem of amount is inaccurate.
Further, is equipped with partition plate in sampling cavity, the region formation sample between partition plate and valve module mixes sub- chamber, on partition plate
Set allow sample transfer bar to be inserted into cross sample hole；Sample transfer bar has load sample portion and insertion section, and load sample portion determines with crossing sample hole and being formed to sample
Unit is measured, the diameter of insertion section increases along the direction away from load sample portion, and sample hole was closed in insertion section.By setting load sample portion and mistake
The clearance distance in sample hole, can quantitatively enter the sample that sample mixes sub- intracavitary.
Further, testing agency has test chamber, and test block mounting bracket is plugged in test chamber, and test block mounting bracket will detect
Chamber is divided into receiving test block（Such as test paper）The sub- chamber of test and accommodate the sub- chamber of sample of sample, the sub- chamber of sample connects with sample presentation passage
It is logical；Test block mounting bracket is equipped with the jack for allowing test block to be inserted into the sub- chamber of sample；Test block mounting bracket is connected as a single entity with valve chamber,
There is through hole on test block mounting bracket.The through hole can be used as demoulding hole.
Further, test chamber is separated and places annex product by test block mounting bracket（Such as drier）The sub- chamber of annex, annex
Chamber is adjacent with detecting sub- chamber, and the through hole connection sub- chamber of annex is with detecting sub- chamber.
Further, sample transfer bar is connected with sample presentation lid, and sample presentation lid coordinates with sampling cavity, the detachably connected anti-error behaviour of sample presentation lid
Make component, anti-misoperation component is made of limited cover and connection unit, and connection unit is combined by elastic bayonet lock-buckle and pin-hole
Bit combination is formed.Elastic bayonet lock is located at sample presentation lid, and buckle is located at limited cover；Or elastic bayonet lock is located at limited cover, be buckled position
In sample presentation lid.Pin is located at sample presentation lid, and hole is located at limited cover；Or pin is located at limited cover, hole is located at sample presentation lid.
The invention reside in：
The 1st, sample portion and sealing were set in push rod, realize the quantitative conveying of sample.
2nd, sample dosing unit and realize accurately limiting to sampling quantity.
3rd, valve chamber is sealed with plug, plug can completely disengage valve chamber, fully open valve chamber, avoid Obstruct membrane interference sample
The problem of this flow, ensure the quantitative conveying of sample.
4th, through hole is set on test mounting bracket, easy to demould.
Brief description of the drawings
Fig. 1 is the schematic diagram of the present invention.
Fig. 2 is the A portions enlarged drawing of Fig. 1.
Fig. 3 is the schematic diagram of push rod,（a）It is the schematic diagram without plug in push rod,（b）It is that plug is installed on push rod
On schematic diagram.
Fig. 4 is the schematic diagram of sampling cavity.
Fig. 5 is the schematic diagram of test block mounting bracket and valve chamber one.
Fig. 6 is the schematic diagram of sample transfer bar.
Embodiment
Embodiment 1
As shown in Figure 1, a kind of sample collection detector, has sampling mechanism 1, testing agency 2 and means of communication 3, sampling mechanism 1
With sampling cavity 1-1 and sample transfer bar 1-2, sample transfer bar 1-2 insertion sampling cavities 1-1 completes sampling；There is means of communication 3 connection to sample
The chamber 1-1 and sample presentation passage 3-1 of testing agency 2, has valve module 4, valve module 4 is initial between sample presentation passage 3-1 and sampling cavity 1-1
When close, sample presentation passage 3-1 isolate with sampling cavity 1-1, sample transfer bar 1-2 trigger valve module 4 open, connect sample presentation passage 3-1 and
Sampling cavity 1-1.
Valve module 4 has valve chamber 4-1, push rod 4-2 and closure member 4-3, and valve chamber 4-1 connection sampling cavity 1-1 and sample presentation lead to
The outlet of road 3-1, closure member 4-3 sealing valve chamber 4-1；Means of communication 3, which has, provides the push rod 4-2 space 3-2 of insertion.
Such as Fig. 3（a）Shown, the concrete structure of push rod 4-2 is：Push rod 4-2 has carrier 4-21, sealing 4-
22 and cross the bottom of sample portion 4-23, carrier 4-21 and sample transfer bar 1-2 and match, during the sample transfer bar 1-2 triggering unlatchings of valve module 4, mistake
Sample portion 4-23 makes closure member 4-3 open the outlet 4-11 of valve chamber 4-1, and after quantitative sample presentation, sealing 4-22 closeding valve cavities 4-1 goes out
Mouth 4-11.
Sealing 4-22 is located at carrier 4-21 and crosses between sample portion 4-23, the outlet 4- of sealing 4-22 and valve chamber 4-1
11 interference fits, the outer surface of sample portion 4-23 excessively are provided with axial sample groove 4-231 excessively.Can also be：Cross sample portion 4-23 and valve chamber
4-1 has gap.The gap crossed sample groove 4-231 or crossed between sample portion 4-23 and valve chamber 4-1 forms runner, and sample mixed liquor is through stream
Road enters means of communication 3.By the length, the excessively size of sample groove 4-231 or mistake sample portion 4-23 and the valve chamber that set sample portion 4-23
The size in the gap between 4-1, realizes the quantitative conveying to liquid sample.
As shown in figure 3, carrier 4-21 is piston, piston has outwardly extending dish-shaped fin 4-211, and dish-shaped fin is
Flexible piece.The deformation during entrance of butterfly fin press-in valve chamber 4-1, the entrance of closeding valve cavity 4-1.After sample presentation, piston and
Sealing dual-seal valve module, ensures the accuracy of quantitative sample presentation.
As shown in Fig. 2, the concrete structure of closure member 4-3 is：Closure member 4-3 is the plug for clogging valve chamber 4-1.Such as Fig. 3
（b）Shown, plug crosses sample portion 4-23 between sealing 4-22 and plug on push rod 4-2.In use, use sample presentation
Bar 1-2 triggers push rod 4-2, when plug leaves valve chamber 4-1 outlets 4-11, crosses sample portion 4-23 and reaches valve chamber 4-1 outlets 4-11, liquid
Body sample enters testing agency 2 by crossing sample portion 4-23, and push rod 4-2 is continued to run with, sealing 4-22 closeding valve cavities 4-1 outlets 4-
11, sample presentation is completed.Means of communication 3, which has, provides the push rod 4-2 space 3-2 of operation.
To improve the reliability of closure member 4-3, closure member 4-3 further includes the Obstruct membrane for being arranged at valve chamber 4-1 outlets 4-11,
As shown in Figure 2.Including plug, outside, double-layer seal isolates sampling cavity 1-1 and testing agency 2 to Obstruct membrane.Inside and outside finger herein
It is inside and outside for opposite valve chamber 4-1.For plug plug in valve chamber 4-1, therefore during push rod 4-2 operations, plug can be by Obstruct membrane
Break completely, avoid the problem that Obstruct membrane completely enclose or partially enclosed sample presentation passage 3-1 and cause the quantitative inaccuracy of sample.
Plug can also be alone plug valve chamber 4-1 outlet 4-11, without being combined in push rod.In use, use sample presentation
Bar 1-2 triggers push rod 4-2, and the sample portion 4-23 that crosses of push rod 4-2 pushes away plug from valve chamber 4-1, and liquid sample is by crossing sample portion
4-23 enters testing agency 2, and plug falls, and does not interfere the flow of sample presentation passage 3-1.
As shown in figure 4, being equipped with partition plate 1-3 in sampling cavity 1-1, the region between partition plate 1-3 and valve module 4 forms sample and mixes
Zygote chamber 1-4, sample mix and solution are contained in sub- chamber 1-4, set allow sample transfer bar 1-2 to be inserted into cross sample hole 1- on partition plate 1-3
5。
As shown in fig. 6, sample transfer bar 1-2 has load sample portion 1-21 and insertion section 1-22, load sample portion 1-21 is with crossing sample hole 1-5 shapes
Into sampling dosing unit, the diameter of insertion section 1-22 increases along the direction away from load sample portion 1-21, when sample transfer bar 1-2 makes push rod
When 4-2 stops sample presentation, insertion section 1-22 closed sample hole 1-5.Load sample portion 1-21 is equipped with tooth, sample be attached to tooth surface and
In the groove of adjacent dentification.By setting the width and depth of the shape of tooth and the groove of adjacent dentification, with reference to load sample portion 1-
21 clearance distance with crossing sample hole 1-5, can quantify the sample entered in the sub- chamber 1-4 of sample mixing.Sample is mixed into sample
After sub- chamber 1-4, sample is set to be substantially dissolved in formation sample mixed liquor in solution.Injecting sample can accurately be set and mix the molten of sub- chamber
Liquid, therefore concentration of the sample in sample mixed liquor accurately controls.
There are sample presentation lid 1-6, sample presentation lid 1-6 and sampling cavity 1-1 matching on sample transfer bar 1-2.
As shown in Figure 1, there is test chamber 2-1, test chamber 2-1 to have venthole 2-2, be plugged in test chamber 2-1 for testing agency 2
Test chamber is divided into receiving test block by test block mounting bracket 2-3, test block mounting bracket（Such as test paper）The sub- chamber 2-11 of test and
The sub- chamber 2-12 of sample of sample is accommodated, the sub- chamber 2-12 of sample is connected with sample presentation passage 3-1.As shown in figure 5, test block mounting bracket 2-
3 are equipped with the jack for allowing test block to be inserted into the sub- chamber 2-12 of sample；Test block mounting bracket 2-3 is connected as a single entity with valve chamber 4-1, test
There is through hole 2-31 on part mounting bracket 2-3.The through hole can be used as demoulding hole.
As shown in Figure 1, test block mounting bracket, which separates test chamber, places annex product（Such as drier）The sub- chamber 2-13 of annex,
The sub- chamber 2-13 of annex is adjacent with detecting sub- chamber 2-11, and the through hole 2-31 connection sub- chamber 2-13 of annex are with detecting sub- chamber 2-11.It can fit
With the whole test chamber 2-1 of desiccant dryness.
As shown in figure 4, valve chamber 4-1 has with the sub- chamber 1-4 of sample mixing the first sub- chambers being connected and is connected with means of communication 3
The second sub- chamber, the entrance of the first sub- chamber is the entrance of valve chamber 4-1, the outlet of the second sub- chamber for valve chamber 4-1 outlet.Push rod
The entrance interference fit of the sub- chambers of the carrier 4-21 of 4-2 and first, so that the entrance of closeding valve cavity 4-1.
In specific actual mechanical process, the load sample portion of sample transfer bar 1-2 carries sample, under the thrust of sample presentation lid 1-3,
It is inserted into the sampling cavity 1-1 in sampling mechanism, partition plate 1-3 is separated out sample from sampling cavity and mixes sub- chamber 1-4, by sending
Sample bar 1-2 and the cooperation for crossing sample hole 1-31, can prevent sample mixed liquor from leaking outside.Sample transfer bar 1-2 passes through the mistake being arranged on partition plate
Sample hole 1-5, load sample portion 1-21 pass through sample hole 1-5, and the sample that sub- intracavitary 1-4 is mixed into sample is quantified.Sample mixes sub- chamber
Solution is loaded with 1-4, after sample transfer bar 1-2 enters wherein, under the action of liquid, sample uniformly spreads out in a liquid,
Form the mixed liquor of sample.By certain time give sample in a liquid disperse after, continue to sample presentation lid 1-6 press, send
Sample bar 1-2 is touched to the carrier 4-21 of push rod 4-2, and under the action of sample transfer bar 1-2, push rod 4-2 is run, push rod 4-
Plug on 2 leaves valve chamber 4-1, and sample mixed liquor is from the means of communication 3 crossed sample portion 4-22 and entered, and through sample presentation passage 3-1
In the sub- chamber 2-12 of sample for reaching testing agency, sample chamber storage sample mixed liquor, sample mixed liquor and test block reaction,
Realize the detection of sample.Meanwhile push rod 4-2 continues to run until the outlet of sealing 4-23 closeding valve cavities 4-1, sample is prevented
This mixed liquor is gone successively in the sub- chamber of sample, quantitatively into the sample mixed liquor of the sub- chamber of sample, can make the sample of the sub- intracavitary of sample
This mixed liquor is reacted with test block enough, and only excessive.
The process is clean, sanitary, easy to operate, realizes quick load and the detection of sample.
Embodiment 2
Difference lies in add the anti-misoperation component being connected with sample presentation lid 1-3 with embodiment 1 for the present embodiment.Remaining structure is equal
It is same as Example 1.
The detachably connected anti-misoperation components of sample presentation lid 1-6, when anti-misoperation component is combined with sample presentation lid 1-6, detection
Mechanism props up anti-misoperation component, prevents sample transfer bar 1-2 from being run towards the direction of valve module 4.
Anti-misoperation component is made of limited cover and connection unit, and connection unit is combined by elastic bayonet lock-buckle and pin-hole
Bit combination is formed.Elastic bayonet lock is located at sample presentation lid 1-6, and buckle is located at limited cover；Or elastic bayonet lock is located at limited cover, buckle
Positioned at sample presentation lid 1-6.Pin is located at sample presentation lid 1-3, and hole is located at limited cover；Or pin is located at limited cover, hole is located at sample presentation lid 1-6.
After anti-misoperation component is disengaged from sample presentation lid 1-6, sample presentation lid 1-6 could promote sample transfer bar under external force
The direction operation of the super close valve modules 4 of 1-2.
Content described in this specification embodiment is only enumerating to the way of realization of inventive concept, protection of the invention
Scope is not construed as being only limitted to the concrete form that embodiment is stated, protection scope of the present invention is also and in art technology
Personnel conceive according to the present invention it is conceivable that equivalent technologies mean.
Claims (7)
1. a kind of sample collection detector, it is characterised in that the sample collection detector has sampling mechanism, testing agency and company
Logical mechanism, sampling mechanism have sampling cavity and sample transfer bar, and sample transfer bar insertion sampling cavity completes sampling；Means of communication takes with connection
Sample chamber and the sample presentation passage of testing agency, there is a valve module between sample presentation passage and sampling cavity, valve module has a valve chamber, push rod and
Plug, valve chamber connection sampling cavity and sample presentation passage, plug clogs valve chamber when initial；Push rod has carrier, sealing and mistake
The bottom of sample portion, carrier and sample transfer bar matches, and sample transfer bar triggering plug departs from valve chamber, crosses to be formed between sample portion and valve chamber and flow
Road, after quantitative sample presentation, the outlet of sealing closeding valve cavity；Means of communication has the space for providing push rod operation.
2. sample collection detector as claimed in claim 1, it is characterised in that：Sealing position in carrier with cross sample portion it
Between, sealing is interference fitted with valve chamber, and the outer surface in sample portion excessively is provided with axial sample groove excessively；Alternatively, between sample portion and valve chamber have excessively
Gap.
3. sample collection detector as claimed in claim 2, it is characterised in that：Carrier is piston, and piston has to extension
The dish-shaped fin stretched, dish-shaped fin are flexible piece.
4. the sample collection detector as described in one of claim 1-3, it is characterised in that：Testing agency has test chamber, inspection
Survey intracavitary and plug test block mounting bracket, test chamber is divided into the sub- chamber of test for accommodating test block and accommodates sample by test block mounting bracket
This sub- chamber of sample, the sub- chamber of sample are connected with sample presentation passage；Test block mounting bracket, which is equipped with, allows test block to be inserted into the sub- chamber of sample
Jack；Test block mounting bracket is connected as a single entity with valve chamber, has through hole on test block mounting bracket.
5. sample collection detector as claimed in claim 4, it is characterised in that：Test chamber is separated placement by test block mounting bracket
The sub- chamber of annex of annex product, the sub- chamber of annex is adjacent with detecting sub- chamber, and the through hole connection sub- chamber of annex is with detecting sub- chamber.
6. sample collection detector as claimed in claim 5, it is characterised in that：Partition plate, partition plate and valve group are equipped with sampling cavity
Region between part forms sample and mixes sub- chamber, sets allow sample transfer bar to be inserted into cross sample hole on partition plate；Sample transfer bar has load sample
Portion and insertion section, load sample portion form sampling dosing unit with crossing sample hole, and the diameter of insertion section increases along the direction away from load sample portion,
Closed sample hole in insertion section.
7. sample collection detector as claimed in claim 6, it is characterised in that：Sample transfer bar is connected with sample presentation lid, sample presentation lid with
Sampling cavity coordinates, and the detachably connected anti-misoperation component of sample presentation lid, anti-misoperation component is made of limited cover and connection unit,
Connection unit is combined by elastic bayonet lock-buckle and pin-hole bit combination is formed.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711106194.3A CN107966582A (en) | 2017-11-10 | 2017-11-10 | A kind of sample collection detector |
| US15/899,852 US10772610B2 (en) | 2017-02-22 | 2018-02-20 | Sample collection detector |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711106194.3A CN107966582A (en) | 2017-11-10 | 2017-11-10 | A kind of sample collection detector |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107966582A true CN107966582A (en) | 2018-04-27 |
Family
ID=62000991
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201711106194.3A Pending CN107966582A (en) | 2017-02-22 | 2017-11-10 | A kind of sample collection detector |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN107966582A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2021147352A1 (en) * | 2020-01-23 | 2021-07-29 | 广州万孚生物技术股份有限公司 | In-vitro diagnostic analyzer, reagent card, and mounting structure |
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| WO2021147352A1 (en) * | 2020-01-23 | 2021-07-29 | 广州万孚生物技术股份有限公司 | In-vitro diagnostic analyzer, reagent card, and mounting structure |
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