CN107440925A - A kind of compound method of disposable hand sanitizing fluid - Google Patents
A kind of compound method of disposable hand sanitizing fluid Download PDFInfo
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- CN107440925A CN107440925A CN201610367015.0A CN201610367015A CN107440925A CN 107440925 A CN107440925 A CN 107440925A CN 201610367015 A CN201610367015 A CN 201610367015A CN 107440925 A CN107440925 A CN 107440925A
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- compound method
- sanitizing fluid
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- hand sanitizing
- agitator tank
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/43—Guanidines
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/10—Washing or bathing preparations
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- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
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- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Dermatology (AREA)
- Chemical & Material Sciences (AREA)
- Inorganic Chemistry (AREA)
- Cosmetics (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Abstract
The invention discloses a kind of compound method of disposable hand sanitizing fluid, the product belongs to disinfectant field；The raw material that the present invention uses includes：Medicinal alcohol 70.0 71.0%, acetic acid chlorhexidine 0.8%, water 27.0 28.0%, sorbitan monostearate 0.2%, polyoxyethylene sorbitan fatty acid ester 0.1%, medicinal glycerin 0.4%, dipropylene glycol 0.2%, silver nitrate 0.1%, pigment 0.1%, essence 0.1%；Trichlorine hydramine, tartaric acid, appropriate citric acid and the percentage for being not counted in reaction raw materials；The advantages of compound method is：Simple, the good quality of product using common apparatus, technique；Product is the disposable hand sanitizing fluid of a kind of ICU rooms and public ward, can kill various viruses after dry hand use rapidly, effectively killing includes G+, G bacterium, tubercle bacillus etc., 6 hours long-acting residual activities；Can efficient skin care；Faintly acid formula, meet skin surface weak acid environment, without with water, without rinsing.
Description
Technical field
The invention belongs to disinfectant field, more particularly to the compound method of a kind of hospital ICU rooms and the disposable hand sanitizing fluid of public ward.
Background technology
Disposable hand sanitizing fluid is directly used in and washed one's hands, major advantage is without using towel, water and soap：Non-water washing, can clean both hands whenever and wherever possible, and advantage is：1. effect duration is grown, most long up to 6 hours up to 4-5 hours；2. having the function that gentle skin care, controllable hand oxidative stress, prevent skin injury, moisten care hand skin；3. it can effectively sterilize antivirus.Disposable hand sanitizing fluid species is various, is applicable to the places such as hospital, bank, supermarket, public place of entertainment, school, kindergarten, but product of the present invention is mainly used in the doctor, nurse, the hand disinfection of patient of hospital ICU rooms and public ward.The main component of product has：1. ethanol, specially concentration are 95% medicinal alcohol, it is sterilization that it, which is acted on, and sterilizing mechanismses are：Alcohol molecule has two ends, and one end is hydrophobic, the attraction that can be destroyed between protein interior hydrophobic group；One end is hydrophilic, but it is difficult to the attraction destroyed between the hydrophilic radical outside protein, only alcohol and water exists jointly, the various attractions of holding protein geometry are made to relax simultaneously, protein can just lose physiologically active, therefore, only certain density alcoholic solution, it can be only achieved good disinfection purpose；2. acetic acid chlorhexidine, effect is disinfectant, and outward appearance is white crystalline powder, is dissolved in ethanol, can suppress most of silver nitrate of Gram-negative bacteria and gram-positive bacteria 3., effect is disinfectant；4. medicinal glycerin, effect is NMF；5. dipropylene glycol, effect is NMF；6. sorbitan monostearate, effect is surfactant；7. polyoxyethylene sorbitan fatty acid ester, effect is surfactant；8. pigment, effect is toner；9. essence, effect is deodorant tune.The pH value of hand cleanser need to be such as adjusted in production, the pH value regulators such as trichlorine hydramine, tartaric acid, citric acid can be used, and needed pH value regulation arriving 5-7 according to actual conditions.Product main component is the thimerosal using ethanol and acetic acid chlorhexidine as principle active component, pathogenic entero becteria, pyococcus, saccharomytes, mycobacterium etc. can be killed, appropriate this product can be pressed to hand in the environment of dry cleansing, firmly rubbed after moistening uniform, until drying after covering watch face, reach the effect of quick hand-wrist bones.
The content of the invention
Present invention mainly solves the problem of be to provide a kind of compound method of disposable hand sanitizing fluid, the raw material that this method uses includes：Medicinal alcohol 70.0-71.0 %, acetic acid chlorhexidine 0.8%, water 27.0-28.0%, sorbitan monostearate 0.2%, polyoxyethylene sorbitan fatty acid ester 0.1%, medicinal glycerin 0.4%, dipropylene glycol 0.2%, silver nitrate 0.1%, pigment 0.1%, essence 0.1%；Trichlorine hydramine, tartaric acid, appropriate citric acid and the percentage for being not counted in reaction raw materials.
The present invention can be achieved through the following technical solutions：
A kind of compound method of disposable hand sanitizing fluid, its feature are made up of following steps：
（1）At normal temperatures into the first agitator tank add formula ratio acetic acid chlorhexidine and ethanol, stir to acetic acid chlorhexidine be completely dissolved it is rear stand-by.
（2）Sorbitan monostearate, polyoxyethylene sorbitan fatty acid ester and the water of formula ratio are sequentially added into the second agitator tank at normal temperatures, is stirred, adds the medicinal glycerin of formula ratio, dipropylene glycol stirs.
（3）Whole materials in the first agitator tank are added in the second agitator tank at normal temperatures and blended uniformly, the silver nitrate, essence, pigment for adding formula ratio stir.
（4）PH value is tested, can be filling between can to adjust pH value with a kind of in trichlorine hydramine, tartaric acid, citric acid be 5-7 as between pH value no longer 5-7.
The present invention further technical scheme be：
Step（1）Described medicinal alcohol purity is 95%.
Step（2）Described water is distilled water.
Step（3）Described silver nitrate is pure to analyze.
Step（1）, step（2）, step（3）Described normal temperature is 5-30 DEG C.
The beneficial effects of the invention are as follows：Provide a kind of compound method of disposable hand sanitizing fluid, be the advantages of this method：Simple, the good quality of product using common apparatus, technique；Product is the disposable hand sanitizing fluid of a kind of ICU rooms and public ward, can kill various viruses after dry hand use rapidly, effectively killing includes G+, G- bacterium, tubercle bacillus etc., 6 hours long-acting residual activities；Can efficient skin care, ensure skin integrity, increase sterilizing security and medical personnel safety；Faintly acid formula, meet skin surface weak acid environment, it is compatible with other faintly acid sterile products to use；Without using water, without rinsing, shorten clinical disinfection and wash one's hands the time, improve operating efficiency, reduce cost.
Embodiment
Embodiment 1
Add that to account for acetic acid chlorhexidine that total amount is 0.8% and account for total amount be 70.0% ethanol into the first agitator tank at normal temperatures, stir to acetic acid chlorhexidine be completely dissolved it is rear stand-by；Sequentially added at normal temperatures into the second agitator tank and account for sorbitan monostearate that total amount is 0.2%, account for polyoxyethylene sorbitan fatty acid ester and account for the water that total amount is 28.0% that total amount is 0.1%, stir, add and account for medicinal glycerin that total amount is 0.4%, account for the dipropylene glycol that total amount is 0.2% and stir；Whole materials in the first agitator tank are added in the second agitator tank at normal temperatures and blend uniform, is added and is accounted for silver nitrate that total amount is 0.1%, account for essence that total amount is 0.1%, account for the pigment that total amount is 0.1% and stir；PH value is tested, can be filling between can to adjust pH value with a kind of in trichlorine hydramine, tartaric acid, citric acid be 5-7 as between pH value no longer 5-7.
Embodiment 2
Add that to account for acetic acid chlorhexidine that total amount is 0.8% and account for total amount be 70.25 % ethanol into the first agitator tank at normal temperatures, stir to acetic acid chlorhexidine be completely dissolved it is rear stand-by；Sequentially added at normal temperatures into the second agitator tank and account for sorbitan monostearate that total amount is 0.2%, account for polyoxyethylene sorbitan fatty acid ester and account for the water that total amount is 27.75% that total amount is 0.1%, stir, add and account for medicinal glycerin that total amount is 0.4%, account for the dipropylene glycol that total amount is 0.2% and stir；Whole materials in the first agitator tank are added in the second agitator tank at normal temperatures and blend uniform, is added and is accounted for silver nitrate that total amount is 0.1%, account for essence that total amount is 0.1%, account for the pigment that total amount is 0.1% and stir；PH value is tested, can be filling between can to adjust pH value with a kind of in trichlorine hydramine, tartaric acid, citric acid be 5-7 as between pH value no longer 5-7.
Embodiment 3
Add that to account for acetic acid chlorhexidine that total amount is 0.8% and account for total amount be 70.5 % ethanol into the first agitator tank at normal temperatures, stir to acetic acid chlorhexidine be completely dissolved it is rear stand-by；Sequentially added at normal temperatures into the second agitator tank and account for sorbitan monostearate that total amount is 0.2%, account for polyoxyethylene sorbitan fatty acid ester and account for the water that total amount is 27.5% that total amount is 0.1%, stir, add and account for medicinal glycerin that total amount is 0.4%, account for the dipropylene glycol that total amount is 0.2% and stir；Whole materials in the first agitator tank are added in the second agitator tank at normal temperatures and blend uniform, is added and is accounted for silver nitrate that total amount is 0.1%, account for essence that total amount is 0.1%, account for the pigment that total amount is 0.1% and stir；PH value is tested, can be filling between can to adjust pH value with a kind of in trichlorine hydramine, tartaric acid, citric acid be 5-7 as between pH value no longer 5-7.
Embodiment 4
Add that to account for acetic acid chlorhexidine that total amount is 0.8% and account for total amount be 70.75 % ethanol into the first agitator tank at normal temperatures, stir to acetic acid chlorhexidine be completely dissolved it is rear stand-by；Sequentially added at normal temperatures into the second agitator tank and account for sorbitan monostearate that total amount is 0.2%, account for polyoxyethylene sorbitan fatty acid ester and account for the water that total amount is 27.25% that total amount is 0.1%, stir, add and account for medicinal glycerin that total amount is 0.4%, account for the dipropylene glycol that total amount is 0.2% and stir；Whole materials in the first agitator tank are added in the second agitator tank at normal temperatures and blend uniform, is added and is accounted for silver nitrate that total amount is 0.1%, account for essence that total amount is 0.1%, account for the pigment that total amount is 0.1% and stir；PH value is tested, can be filling between can to adjust pH value with a kind of in trichlorine hydramine, tartaric acid, citric acid be 5-7 as between pH value no longer 5-7.
Embodiment 5
Add that to account for acetic acid chlorhexidine that total amount is 0.8% and account for total amount be 71.0 % ethanol into the first agitator tank at normal temperatures, stir to acetic acid chlorhexidine be completely dissolved it is rear stand-by；Sequentially added at normal temperatures into the second agitator tank and account for sorbitan monostearate that total amount is 0.2%, account for polyoxyethylene sorbitan fatty acid ester and account for the water that total amount is 27.0% that total amount is 0.1%, stir, add and account for medicinal glycerin that total amount is 0.4%, account for the dipropylene glycol that total amount is 0.2% and stir；Whole materials in the first agitator tank are added in the second agitator tank at normal temperatures and blend uniform, is added and is accounted for silver nitrate that total amount is 0.1%, account for essence that total amount is 0.1%, account for the pigment that total amount is 0.1% and stir；PH value is tested, can be filling between can to adjust pH value with a kind of in trichlorine hydramine, tartaric acid, citric acid be 5-7 as between pH value no longer 5-7.
Certainly, the present invention also has other embodiments, the improvement of any technology, principle and the technique done under the spiritual background without departing from the present invention, is within the scope of the present invention.
Claims (5)
1. a kind of compound method of disposable hand sanitizing fluid, its raw material used include：Medicinal alcohol 70.0-71.0 %, acetic acid chlorhexidine 0.8%, water 27.0-28.0%, sorbitan monostearate 0.2%, polyoxyethylene sorbitan fatty acid ester 0.1%, medicinal glycerin 0.4%, dipropylene glycol 0.2%, silver nitrate 0.1%, pigment 0.1%, essence 0.1%；Trichlorine hydramine, tartaric acid, appropriate citric acid and the percentage for being not counted in reaction raw materials, it is characterised in that：
（1）At normal temperatures into the first agitator tank add formula ratio acetic acid chlorhexidine and ethanol, stir to acetic acid chlorhexidine be completely dissolved it is rear stand-by；
（2）Sorbitan monostearate, polyoxyethylene sorbitan fatty acid ester and the water of formula ratio are sequentially added into the second agitator tank at normal temperatures, is stirred, adds the medicinal glycerin of formula ratio, dipropylene glycol stirs；
（3）Whole materials in the first agitator tank are added in the second agitator tank at normal temperatures and blended uniformly, the silver nitrate, essence, pigment for adding formula ratio stir；
（4）PH value is tested, can be filling between can to adjust pH value with a kind of in trichlorine hydramine, tartaric acid, citric acid be 5-7 as between pH value no longer 5-7.
2. a kind of compound method of disposable hand sanitizing fluid according to claim 1, it is characterized in that：Step（1）Described medicinal alcohol purity is 95%.
3. a kind of compound method of disposable hand sanitizing fluid according to claim 1, it is characterized in that：Step（2）Described water is distilled water.
4. a kind of compound method of disposable hand sanitizing fluid according to claim 1, it is characterized in that：Step（3）Described silver nitrate is pure to analyze.
5. a kind of compound method of disposable hand sanitizing fluid according to claim 1, it is characterized in that：Step（1）, step（2）, step（3）Described normal temperature is 5-30 DEG C.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610367015.0A CN107440925A (en) | 2016-05-30 | 2016-05-30 | A kind of compound method of disposable hand sanitizing fluid |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610367015.0A CN107440925A (en) | 2016-05-30 | 2016-05-30 | A kind of compound method of disposable hand sanitizing fluid |
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| Publication Number | Publication Date |
|---|---|
| CN107440925A true CN107440925A (en) | 2017-12-08 |
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| CN201610367015.0A Pending CN107440925A (en) | 2016-05-30 | 2016-05-30 | A kind of compound method of disposable hand sanitizing fluid |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110613620A (en) * | 2019-10-22 | 2019-12-27 | 佛山市时孖现代家居科技有限公司 | Washing-free alcohol disinfectant, using device and application thereof |
| CN111617103A (en) * | 2020-04-15 | 2020-09-04 | 温军海 | Silver ion graphene oxide-containing antibacterial and disinfectant protective cleaning solution |
| CN111944617A (en) * | 2020-08-19 | 2020-11-17 | 河南昇阳生物科技有限公司 | Composite water-free hand sanitizer containing amino acid |
| EP4032403A1 (en) | 2021-01-20 | 2022-07-27 | Galaxy Surfactants Ltd. | Safe and ecofriendly persistent sanitizing gel for topical application |
-
2016
- 2016-05-30 CN CN201610367015.0A patent/CN107440925A/en active Pending
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110613620A (en) * | 2019-10-22 | 2019-12-27 | 佛山市时孖现代家居科技有限公司 | Washing-free alcohol disinfectant, using device and application thereof |
| CN111617103A (en) * | 2020-04-15 | 2020-09-04 | 温军海 | Silver ion graphene oxide-containing antibacterial and disinfectant protective cleaning solution |
| CN111944617A (en) * | 2020-08-19 | 2020-11-17 | 河南昇阳生物科技有限公司 | Composite water-free hand sanitizer containing amino acid |
| EP4032403A1 (en) | 2021-01-20 | 2022-07-27 | Galaxy Surfactants Ltd. | Safe and ecofriendly persistent sanitizing gel for topical application |
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Application publication date: 20171208 |